CINXE.COM
Page Not Found | OXLUMO® (lumasiran)
<!DOCTYPE html> <html lang="en" dir="ltr" prefix="content: http://purl.org/rss/1.0/modules/content/ dc: http://purl.org/dc/terms/ foaf: http://xmlns.com/foaf/0.1/ og: http://ogp.me/ns# rdfs: http://www.w3.org/2000/01/rdf-schema# schema: http://schema.org/ sioc: http://rdfs.org/sioc/ns# sioct: http://rdfs.org/sioc/types# skos: http://www.w3.org/2004/02/skos/core# xsd: http://www.w3.org/2001/XMLSchema# "> <head> <meta charset="utf-8" /> <link rel="canonical" href="https://www.oxlumohcp.com/Page-Not-Found" /> <meta name="robots" content="noindex, noarchive" /> <link rel="image_src" href="/sites/default/files/2022-04/oxlumo-logo-large.png" /> <meta property="og:site_name" content="OXLUMO® (lumasiran)" /> <meta property="og:url" content="https://www.oxlumohcp.com/Page-Not-Found" /> <meta property="og:title" content="Page Not Found | OXLUMO® (lumasiran)" /> <meta property="og:image" content="https://www.oxlumohcp.com/sites/default/files/2022-04/oxlumo-logo-large.png" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:title" content="Page Not Found | OXLUMO® (lumasiran)" /> <meta name="twitter:url" content="https://www.oxlumohcp.com/Page-Not-Found" /> <meta name="twitter:image" content="https://www.oxlumohcp.com/sites/default/files/2022-04/oxlumo-logo-large.png" /> <meta name="Generator" content="Drupal 9 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <title>Page Not Found | OXLUMO® (lumasiran)</title> <link rel="stylesheet" href="https://use.typekit.net/zxa7yax.css"> <link rel="apple-touch-icon" sizes="180x180" href="/themes/oxlumo/images/apple-touch-icon.png"> <link rel="icon" type="image/png" sizes="32x32" href="/themes/oxlumo/images/favicon-32x32.png"> <link rel="manifest" href="/site.webmanifest"> <meta name="theme-color" content="#006b5b" /> <meta name="google-site-verification" content="1Qft166SM8zZatykeopxyPDONoIkgdOrCrQ3PUngiNU" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/ajax-progress.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/align.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/autocomplete-loading.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/fieldgroup.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/container-inline.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/clearfix.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/details.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/hidden.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/item-list.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/js.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/nowrap.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/position-container.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/progress.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/reset-appearance.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/resize.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/sticky-header.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/system-status-counter.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/system-status-report-counters.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/system-status-report-general-info.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/tabledrag.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/tablesort.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/tree-child.module.css?so31y4" /> <link rel="stylesheet" media="all" href="/modules/paragraphs/css/paragraphs.unpublished.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/core/assets/vendor/normalize-css/normalize.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/core/normalize-fixes.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/action-links.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/breadcrumb.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/button.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/collapse-processed.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/container-inline.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/details.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/exposed-filters.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/field.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/form.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/icons.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/inline-form.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/item-list.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/link.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/links.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/menu.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/more-link.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/pager.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/tabledrag.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/tableselect.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/tablesort.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/tabs.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/textarea.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/ui-dialog.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/messages.css?so31y4" /> <link rel="stylesheet" media="all" href="/core/themes/classy/css/components/node.css?so31y4" /> <link rel="stylesheet" media="all" href="/themes/oxlumo/css/styles.min.css?so31y4" /> <link rel="stylesheet" media="all" href="/themes/oxlumo/css/vendor/select2.min.css?so31y4" /> <link rel="stylesheet" media="all" href="/themes/oxlumo/css/vendor/slick.css?so31y4" /> <script src="https://use.fontawesome.com/releases/v5.13.1/js/all.js" defer crossorigin="anonymous"></script> <script src="https://use.fontawesome.com/releases/v5.13.1/js/v4-shims.js" defer crossorigin="anonymous"></script> </head> <body class="page-node-14 page-node-type-page 404 day14 hcp path-tel1-833-256-2748"> <a href="#main-content" class="visually-hidden focusable skip-link"> Skip to main content </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <header role="banner"> <div class="header_top"> <div class="wrapper"> <div class="region region-header-top"> <nav role="navigation" aria-labelledby="block-utilitynavigation-mobile-menu" id="block-utilitynavigation-mobile" class="mobile block block-menu navigation menu--utility-navigation"> <p class="visually-hidden" id="block-utilitynavigation-mobile-menu">Utility Navigation (mobile)</p> <ul class="menu menu--utility-navigation"> <li class="first"> <span class="residents_mobile">For US Healthcare Professionals Only</span> </li> <li> <a href="tel:1-833-256-2748" class="hide_mobile">Questions? Call 1‑833‑256‑2748</a> </li> <li> <a href="#ISI" class="js-open-isi">Important Safety Information </a> </li> <li> <a href="https://www.alnylam.com/oxlumo-us-prescribing-information" target="_blank" class="fpi">Full Prescribing Information</a> </li> <li class="last"> <a href="https://www.oxlumo.com" class="patient-link show-hcp">Patient Site</a> </li> </ul> </nav> </div> </div> </div> <div class="header_middle"> <div class="wrapper"> <div class="region region-header-first"> <div id="block-oxlumologo" class="block block-block-content block-block-content46d02fd2-1f4e-4bdc-82ea-1dac714c5c84"> <div class="field--item"><div class="logo"><a href="/"><img alt="OXLUMO® (lumasiran) Logo" src="/themes/oxlumo/images/oxlumo-lumasiran-logo.png" /></a></div> </div> </div> </div> <div class="region region-header-second"> <nav role="navigation" aria-labelledby="block-utilitynavigation-menu" id="block-utilitynavigation" class="block block-menu navigation menu--utility-navigation"> <p class="visually-hidden" id="block-utilitynavigation-menu">Utility Navigation (desktop)</p> <ul class="menu menu--utility-navigation"> <li class="first"> <span class="residents_mobile">For US Healthcare Professionals Only</span> </li> <li> <a href="tel:1-833-256-2748" class="hide_mobile">Questions? Call 1‑833‑256‑2748</a> </li> <li> <a href="#ISI" class="js-open-isi">Important Safety Information </a> </li> <li> <a href="https://www.alnylam.com/oxlumo-us-prescribing-information" target="_blank" class="fpi">Full Prescribing Information</a> </li> <li class="last"> <a href="https://www.oxlumo.com" class="patient-link show-hcp">Patient Site</a> </li> </ul> </nav> <nav role="navigation" aria-labelledby="block-mainnavigation-menu" id="block-mainnavigation" class="block block-menu navigation menu--main"> <p class="visually-hidden" id="block-mainnavigation-menu">Main navigation</p> <input type="checkbox" name="mobile_btn" class="mobile_btn_ckbox"> <div class="mobile_btn"> <label for="mobile_btn"> <span></span> <span></span> <span></span> </label> </div> <ul class="menu menu--main"> <li class="first"> <a href="/primary-hyperoxaluria-type-1-background" class="hide-day1 show-hcp" data-drupal-link-system-path="node/16">About PH1</a> </li> <li> <a href="/how-oxlumo-works" class="hide-day1 show-hcp" data-drupal-link-system-path="node/17">About OXLUMO<span class="hide_desktop">®</span></a> </li> <li> <a href="/efficacy-and-safety" data-drupal-link-system-path="node/18">Efficacy & Safety</a> </li> <li> <a href="/dosing-and-administration" data-drupal-link-system-path="node/19">Dosing & Administration</a> </li> <li> <a href="/patient-support" data-drupal-link-system-path="node/20">Patient Support Services</a> </li> <li> <a href="/sign-up-for-updates" class="hide-day1" data-drupal-link-system-path="node/4">Get Updates</a> </li> <li> <a href="" class="show-hcp-only hide-day14">Connect With a Representative</a> </li> <li> <a href="tel:1-833-256-2748" class="mobile_call"><span class="title">For Alnylam Assist™</span> <span class="call_box"> <strong>Call <span class="number">1-833-256-2748</span></strong><br> <span class="hours">Monday-Friday, 8<sub> AM</sub>-6<sub> PM</sub></span></a> </li> <li class="last"> <a href="https://www.oxlumo.com" class="patient_site">PATIENT SITE</a> </li> </ul> </nav> </div> <div class="region region-header-third"> <div id="block-connectbutton" class="block block-block-content block-block-contentac762462-41f1-4379-a040-8cb090514b2c"> <div class="field--item"><p><a class="btn js-close-isi js-close-mobile js-open-corp-inter" href="https://alnylamconnect.com/oxlumo">CONNECT WITH A REPRESENTATIVE</a></p> </div> </div> </div> </div> </div> <div class="header_bottom"> <div class="wrapper"> </div> </div> </header> <main role="main" class="main-container js-quickedit-main-content"> <div class="region region-content-top"> <div data-drupal-messages-fallback class="hidden"></div> </div> <section> <a id="main-content"></a> <div class="region region-content"> <div id="block-oxlumo-content" class="block block-system block-system-main-block"> <article data-history-node-id="14" role="article" about="/Page-Not-Found" typeof="schema:WebPage" class="node node--type-page node--view-mode-full"> <span property="schema:name" content="Page Not Found" class="rdf-meta hidden"></span> <div class="node__content"> <div class="field field--name-field-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <section class="hero green smaller_mobile oops" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><div class="h2"><span><strong>OOPS</strong></span> WE COULDN'T FIND THE PAGE YOU ARE LOOKING FOR.</div> <div class="caption">Grace*<br /> Person with PH1</div> </div> </div> </div> </div> </div> </div> </section> </div> <div class="field--item"> <section class="callout white bigger_btns pt-16 pb-64" > <div class="wrapper"> <div class="field field--name-field-sub-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--full-html-content paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-content field--type-text-long field--label-hidden field--items"> <div class="field--item"><p class="hero_note">*Alnylam is proud to feature real patients in our advertising. Patients may or may not be on an Alnylam therapy.</p> <h1 style="margin-bottom: 18px;">The page you are looking for might have been removed or had its name change, or is temporarily unavailable</h1> <p>Please try the following:</p> <ul style="border-bottom: 1px solid transparent;"> <li>If you typed the page’s URL in the address bar, make sure that it was entered correctly</li> <li>Open the home page and then use the navigation bar to locate the page</li> <li>Use the Back button to try another link</li> </ul> <p><a class="btn arrow" href="/" style="margin-bottom: 24px; border-bottom: 1px solid transparent;">Return to Home Page</a><span class="hide_mobile"> </span><a class="btn btn-secondary arrow" href="/" onclick="history.go(-1); return false;">Go Back</a></p> </div> </div> </div> </div> </div> </div> </section> </div> </div> </div> </article> </div> </div> </section> <div class="region region-content-bottom"> <div id="block-importantsafetyinformation" class="isi block block-block-content block-block-content63d76fc1-b7f0-475f-917b-98825b6fba84"> <span class="close-isi"></span> <span class="open-isi"></span> <div class="field--item"><p class="h3">IMPORTANT SAFETY INFORMATION</p> <p><strong>Adverse Reactions</strong><br /> The most common (≥20%) adverse reaction reported in patients treated with OXLUMO was injection site reaction. Injection site reactions included erythema, swelling, pain, hematoma, pruritus, and discoloration.</p> <p><strong>Pregnancy and Lactation</strong><br /> No data are available on the use of OXLUMO in pregnant women. No data are available on the presence of OXLUMO in human milk or its effects on breastfed infants or milk production. Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for OXLUMO and any potential adverse effects on the breastfed child from OXLUMO or the underlying maternal condition.</p> <p class="h3">INDICATION</p> <p>OXLUMO is indicated for the treatment of primary hyperoxaluria type 1 (PH1) to lower urinary and plasma oxalate levels in children and adults.</p> <p><strong style="color: inherit;">For additional information about OXLUMO, please see the full <a href="https://www.alnylam.com/oxlumo-us-prescribing-information" target="_blank">Prescribing Information</a>.</strong></p> </div> </div><div id="block-corporateinterstitial" class="block block-block-content block-block-content6e2edfba-b157-4b45-b715-dc959aab885e"> <div class="field--item"><div class="popup" id="corp_inter"> <div class="wrapper"><a class="close js-close-popup" href="#">×</a> <p class="h3">You are now leaving OXLUMOHCP.com</p> <p>You are now being directed to another Alnylam website.</p> <p><a class="btn link js-close-popup" href="#">Visit Site</a> <a class="btn btn-secondary js-close-popup" href="#">Cancel</a></p> </div> </div> <div class="popup" id="inter"> <div class="wrapper"><a class="close js-close-popup" href="#">×</a> <p class="h3">You are now leaving OXLUMOHCP.com</p> <p>Links to all outside sites are provided as a reference for our visitors. Alnylam Pharmaceuticals does not endorse and is not responsible for the content on sites that are not owned and operated by Alnylam Pharmaceuticals.</p> <p><a class="btn link js-close-popup" href="#">Visit Site</a> <a class="btn btn-secondary js-close-popup" href="#">Cancel</a></p> </div> </div> </div> </div> <div id="block-duplicateemailmodal" class="block block-block-content block-block-contentbde43fa6-261b-4b45-abb2-197faa4ceae3"> <div class="field--item"><div class="popup" id="dupe_email"> <div class="wrapper"><a class="close" href="#">×</a> <p class="h3">This email address is already in use</p> <p>Please select Cancel to enter another email address, or select Update to receive an email that will allow you to update your preferences.</p> <p><a class="btn update" href="#">Update</a> <a class="btn btn-secondary js-close-popup" href="#">Cancel</a></p> </div> </div> </div> </div> <div id="block-hcpprompt" class="block block-block-content block-block-content552afe24-b840-4397-928c-749ec5060ddf"> <div class="field--item"><div class="popup" id="hcp_prompt"> <div class="wrapper"><a class="close" href="#">×</a> <p class="text-align-center"><strong>This site is intended for US healthcare professionals. Please confirm you are a US healthcare professional. </strong></p> <p class="text-align-center"><a class="js-close-hcp btn" href="#">I am a US Healthcare Professional</a> <a class="btn" href="https://www.oxlumo.com/">I am NOT a US Healthcare Professional</a></p> </div> </div> </div> </div> </div> </main> <footer role="contentinfo"> <div class="wrapper"> <div class="region region-footer-first"> <div id="block-alnylamlogo" class="logo block block-block-content block-block-contentdc1898bc-1cea-4624-9e06-ae6b4ddbf394"> <div class="field--item"><p><a class="js-open-corp-inter" href="https://www.alnylam.com" target="_blank"><img alt="Alnylam Logo" src="/themes/oxlumo/images/alnylam-pharmaceuticals-logo.png" /></a></p> <p><a> </a></p> </div> </div> </div> <div class="region region-footer-second"> <div id="block-legalnoticehcp" class="block block-block-content block-block-contenta04ac597-1bf8-49b2-8ea6-32a41c10f916"> <div class="field--item"><p>OXLUMO, Alnylam Assist, and their associated logos are trademarks of Alnylam Pharmaceuticals, Inc.<br /> © 2024 Alnylam Pharmaceuticals, Inc. All rights reserved.</p> <p>This site is intended for US audiences. GO1-USA-00248</p> </div> </div> </div> <div class="region region-footer-third"> <nav role="navigation" aria-labelledby="block-footer-menu" id="block-footer" class="block block-menu navigation menu--footer"> <p class="visually-hidden" id="block-footer-menu">Footer</p> <ul class="menu menu--footer"> <li class="first"> <a href="https://alnylampolicies.com/privacy" class="js-open-corp-inter">Privacy Policy</a> </li> <li> <a href="https://alnylampolicies.com/legal" class="js-open-corp-inter">Legal Notice</a> </li> <li> <a href="https://www.alnylam.com/contact-us/" class="js-open-corp-inter">Contact Us</a> </li> <li class="last"> <a href="/sitemap" data-drupal-link-system-path="node/10">Site Map</a> </li> </ul> </nav> </div> </div> </footer> </div> <script src="/core/assets/vendor/jquery/jquery.min.js?v=3.6.3"></script> <script src="/themes/oxlumo/js/scripts.min.js?so31y4"></script> <script src="/themes/oxlumo/js/vendor/select2.min.js?so31y4"></script> <script src="/themes/oxlumo/js/vendor/jquery.visible.min.js?so31y4"></script> <script src="/themes/oxlumo/js/vendor/slick.min.js?so31y4"></script> <script src="/themes/oxlumo/js/vendor/jquery-input-mask-phone-number.js?so31y4"></script> <script src="https://cdnjs.cloudflare.com/ajax/libs/babel-polyfill/7.4.4/polyfill.min.js"></script> <script src="https://maps.googleapis.com/maps/api/js?key=AIzaSyCzCVntPd9dh1pZK5BxW6bikUg0kU5ibAA&libraries=geometry" async defer></script> </body> </html>