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KEGG MODULE: M00823
<!doctype html> <html><head> <title>KEGG MODULE: M00823</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1745798809"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1745798809"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1745798809" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « '+hide; } 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form.setAttribute(key,params[key]); } else{ var obj = document.createElement('input'); obj.setAttribute('type','hidden'); obj.setAttribute('name',key); obj.setAttribute('value',params[key]); form.appendChild(obj); } } form.submit(); } window.onload=function(){window.focus();init();}; //---> </script> </head> <body> <div> <table border=0 cellpadding=0 cellspacing=0><tr><td> <table border=0 cellpadding=0 cellspacing=0 width="650"><tr><td width=70><a href="/kegg/kegg2.html"><img align="middle" alt="KEGG" border=0 src="/Fig/bget/kegg3.gif"></a></td><td> </td><td><a name="module:M00823"></a><font class="title3">MODULE: M00823</font></td><td class="tar vbot"><button class="btn" onclick="javascript:void(window.open('/kegg/document/help_bget_module.html','KEGG_Help','toolbar=no,location=no,directories=no,width=720,height=640,resizable=yes,scrollbars=yes'));return false;">Help</button></td></tr></table><form method="post" action="/entry/" enctype="application/x-www-form-urlencoded" id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr3 w1"> <table width="650" class="w2"> <tr><th class="th30 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td30 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">M00823 Pathway Module <br> </span></code></td></tr></table></td></tr> <tr><th class="th31 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td31 defd"><div class="cel"><div class="cel">Chlortetracycline biosynthesis, pretetramide => chlortetracycline<br> </div></div></td></tr> <tr><th class="th30 deft tal vtop"><span class="nowrap">Definition</span></th> <td class="td30 defd"><div class="cel"><div class="cel">K14251 K14252 K14253 K14254 K14255 K14256 K21301 K14257+<wbr>K21297<br> </div></div></td></tr> <tr><th class="th31 deft tal vtop"><span class="nowrap">Diagram</span></th> <td class="td31 defd"><div class="mdthumb"><a href="/module/M00823"><img class="center" src="/kegg/misc/thumbnail/M00823.gif" alt="M00823"></a></div><br></td></tr> <tr><th class="th30 deft tal vtop"><span class="nowrap">Orthology</span></th> <td class="td30 defd"><div class="cel"><div class="fll"><a href="/entry/K14251">K14251</a> </div><div style="margin-left:16.8px">oxyF; C-methyltransferase [EC:2.1.1.-] [RN:<a href="/entry/R09189">R09189</a>]</div><div class="fcb"></div><div class="fll"><a href="/entry/K14252">K14252</a> </div><div style="margin-left:16.8px">oxyL; 6-methylpretetramide 4-monooxygenase / 4-hydroxy-6-methylpretetramide 12a-monooxygenase [EC:<a href="/entry/1.14.13.232">1.14.13.232</a> <a href="/entry/1.14.13.233">1.14.13.233</a>] [RN:<a href="/entry/R09190">R09190</a> <a href="/entry/R05462">R05462</a>]</div><div class="fcb"></div><div class="fll"><a href="/entry/K14253">K14253</a> </div><div style="margin-left:16.8px">oxyE; 6-methylpretetramide 4-monooxygenase [EC:<a href="/entry/1.14.13.232">1.14.13.232</a>] [RN:<a href="/entry/R05463">R05463</a>]</div><div class="fcb"></div><div class="fll"><a href="/entry/K14254">K14254</a> </div><div style="margin-left:16.8px">oxyQ; aminotransferase [RN:<a href="/entry/R09197">R09197</a>]</div><div class="fcb"></div><div class="fll"><a href="/entry/K14255">K14255</a> </div><div style="margin-left:16.8px">oxyT, ctcO, cts6; 4-amino-anhydrotetracycline N4-methyltransferase [EC:<a href="/entry/2.1.1.335">2.1.1.335</a>] [RN:<a href="/entry/R09191">R09191</a>]</div><div class="fcb"></div><div class="fll"><a href="/entry/K14256">K14256</a> </div><div style="margin-left:16.8px">oxyS, cts8; anhydrotetracycline 6-monooxygenase / 5a,11a-dehydrotetracycline 5-monooxygenase [EC:<a href="/entry/1.14.13.38">1.14.13.38</a> <a href="/entry/1.14.13.234">1.14.13.234</a>] [RN:<a href="/entry/R04060">R04060</a> <a href="/entry/R09198">R09198</a>]</div><div class="fcb"></div><div class="fll"><a href="/entry/K21301">K21301</a> </div><div style="margin-left:16.8px">oxyR; 5a,11a-dehydrotetracycline reductase [EC:<a href="/entry/1.3.98.4">1.3.98.4</a>] [RN:<a href="/entry/R09192">R09192</a> <a href="/entry/R05459">R05459</a>]</div><div class="fcb"></div><div class="fll"><a href="/entry/K14257">K14257</a> </div><div style="margin-left:16.8px">ctcP; tetracycline 7-halogenase [EC:<a href="/entry/1.14.19.49">1.14.19.49</a>] [RN:<a href="/entry/R11478">R11478</a>]</div><div class="fcb"></div><div class="fll"><a href="/entry/K21297">K21297</a> </div><div style="margin-left:16.8px">ctcQ; flavin reductase (NADH) [EC:<a href="/entry/1.5.1.36">1.5.1.36</a>]</div><div class="fcb"></div></div><button class="btn" onclick="location.href='https://www.kegg.jp/kegg-bin/view_ortholog_table?md=M00823';return false;">Ortholog table</button><button class="btn" onclick="location.href='/kegg-bin/show_taxonomy?id=M00823';return false;">Taxonomy</button></td></tr> <tr><th class="th31 deft tal vtop"><span class="nowrap">Class</span></th> <td class="td31 defd"><div class="cel">Pathway modules; Biosynthesis of terpenoids and polyketides; Type II polyketide biosynthesis<br> <button class="btn" onclick="location.href='/kegg-bin/search_htext?htext=ko00002.keg&option=-a&query=M00823';return false;">BRITE hierarchy</button></div></td></tr> <tr><th class="th30 deft tal vtop"><span class="nowrap">Pathway</span></th> <td class="td30 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map00253+M00823">map00253</a> </span></td><td>Tetracycline biosynthesis</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01057+M00823">map01057</a> </span></td><td>Biosynthesis of type II polyketide products</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01100+M00823">map01100</a> </span></td><td>Metabolic pathways</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01110+M00823">map01110</a> </span></td><td>Biosynthesis of secondary metabolites</td></tr></table></td></tr> <tr><th class="th31 deft tal vtop"><span class="nowrap">Reaction</span></th> <td class="td31 defd"><div class="cel"><div class="fll"><a href="/entry/R09189">R09189</a> </div><div style="margin-left:16.8px"><a href="/entry/C18295">C18295</a> -> <a href="/entry/C06629">C06629</a></div><div class="fcb"></div><div class="fll"><a href="/entry/R05463">R05463</a> </div><div style="margin-left:16.8px"><a href="/entry/C06629">C06629</a> -> <a href="/entry/C06628">C06628</a></div><div class="fcb"></div><div class="fll"><a href="/entry/R05462">R05462</a> </div><div style="margin-left:16.8px"><a href="/entry/C06628">C06628</a> -> <a href="/entry/C06627">C06627</a></div><div class="fcb"></div><div class="fll"><a href="/entry/R09190">R09190</a> </div><div style="margin-left:16.8px"><a href="/entry/C06629">C06629</a> -> <a href="/entry/C06627">C06627</a></div><div class="fcb"></div><div class="fll"><a href="/entry/R09197">R09197</a> </div><div style="margin-left:16.8px"><a href="/entry/C06627">C06627</a> -> <a href="/entry/C06654">C06654</a></div><div class="fcb"></div><div class="fll"><a href="/entry/R09191">R09191</a> </div><div style="margin-left:16.8px"><a href="/entry/C06654">C06654</a> -> <a href="/entry/C02811">C02811</a></div><div class="fcb"></div><div class="fll"><a href="/entry/R04060">R04060</a> </div><div style="margin-left:16.8px"><a href="/entry/C02811">C02811</a> -> <a href="/entry/C03206">C03206</a></div><div class="fcb"></div><div class="fll"><a href="/entry/R05459">R05459</a> </div><div style="margin-left:16.8px"><a href="/entry/C03206">C03206</a> -> <a href="/entry/C06570">C06570</a></div><div class="fcb"></div><div class="fll"><a href="/entry/R11478">R11478</a> </div><div style="margin-left:16.8px"><a href="/entry/C06570">C06570</a> -> <a href="/entry/C06571">C06571</a></div><div class="fcb"></div></div></td></tr> <tr><th class="th30 deft tal vtop"><span class="nowrap">Compound</span></th> <td class="td30 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C18295">C18295</a> </span></td><td>Pretetramid</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C06629">C06629</a> </span></td><td>6-Methylpretetramide</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C06628">C06628</a> </span></td><td>4-Hydroxy-6-methylpretetramide</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C06627">C06627</a> </span></td><td>4-Keto-anhydrotetracycline</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C06654">C06654</a> </span></td><td>4-Amino-anhydrotetracycline</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C02811">C02811</a> </span></td><td>Anhydrotetracycline</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C03206">C03206</a> </span></td><td>5a,11a-Dehydrotetracycline</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C06570">C06570</a> </span></td><td>Tetracycline</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/C06571">C06571</a> </span></td><td>Chlortetracycline</td></tr></table></td></tr> <tr><th class="th31 deft tal vtop"><span class="nowrap">RModule</span></th> <td class="td31 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/kegg/reaction/rm035.html">RM035</a> </span></td><td>Transamination and N,N-dimethylation in polyketide biosynthesis</td></tr></table></td></tr> <tr><th class="th30 deft tal vmid"><span class="nowrap">LinkDB</span></th> <td class="td30 defd"><button class="btn" onclick="location.href='https://www.genome.jp/dbget-bin/get_linkdb?module+M00823';return false;">All DBs</button></td></tr> </table></td></tr></table> <br></td></tr></table> <a href="/dbget/">DBGET</a> integrated database retrieval system</div> </body> </html>