vib.be - Discovery Sciences

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class="region__inner"> <div class="block block--system block--system-main-block" id="block-system-main-block" id=""> <article class="node node--type-page node--view-mode-full"> <div class="node__content"> <div class="layout--layout-onecol tocbotized"> <div class="layout__region layout__region--content"> <div class="block block--entityone-layout-builder block--layout-builder-entity-labelnodepage container container--large block-layout-builder-entity-label page-title--hidden" id=""> <h1 class="page-title visually-hidden">Discovery Sciences</h1> </div> <div class="small-banner full-width block-header-banner-block text-white overlay-dark image-focus--" id="banner-block-218"> <div class="text-wrapper"> <div class="header-title"> <h1 class="spoof-h2 field field--name-field-title field--type-string title field__item">Discovery Sciences</h1> </div> <div class="clearfix text-formatted field field--name-field-banner-intro field--type-text-long field--label-hidden field__item"><p><span>Het VIB Discovery Sciences team richt zich op het beschikbaar maken van specifieke expertise voor veelbelovende projecten in VIB labs die vertaald kunnen worden.</span></p></div> </div> <div class="image-background"> <picture> <source srcset="/sites/vib.sites.vib.be/files/styles/small_header_image/public/2023-01/banner_business_Discovery%20Sciences_1500%C3%97560px.png.webp?itok=4v4-xWq8 1x, /sites/vib.sites.vib.be/files/styles/small_header_image_x2/public/2023-01/banner_business_Discovery%20Sciences_1500%C3%97560px.png.webp?itok=44-iRWWd 2x" media="(min-width: 1024px)" type="image/webp" width="1340" height="250"/> <source srcset="/sites/vib.sites.vib.be/files/styles/small_header_image_small/public/2023-01/banner_business_Discovery%20Sciences_1500%C3%97560px.png.webp?itok=rRoQVaUj 1x, /sites/vib.sites.vib.be/files/styles/small_header_image/public/2023-01/banner_business_Discovery%20Sciences_1500%C3%97560px.png.webp?itok=4v4-xWq8 2x" media="(min-width: 768px)" type="image/webp" width="670" height="125"/> <img src="/sites/vib.sites.vib.be/files/styles/small_header_image_small/public/2023-01/banner_business_Discovery%20Sciences_1500%C3%97560px.png.webp?itok=rRoQVaUj" width="670" height="125" alt="Discovery Sciences" title="" loading="lazy" /> </picture> </div> </div> <div class="block block--layout-builder block--inline-blockbreadcrumbs" id="breadcrumbs-de3"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"><h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2><ol><li><a href="/nl" class="primary-color">Home</a><span class="divider">></span></li><li><a href="/nl/business" class="primary-color">Business</a><span class="divider">></span></li><li><span>Discovery sciences</span></li></ol></nav> </div> <div class="block block--layout-builder block--inline-blocktext-one-col aos-init" data-aos=fade-down id="text-one-col-a30"> <h2 class="field field--name-field-title field--type-string title field__item">Van Target tot Toepassing</h2> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>Het vertalen van wetenschappelijk basisonderzoek naar nieuwe geneesmiddelen en agro-biotech innovaties is een onvoorspelbaar proces. Hoewel het potentieel van zulke innovaties voor de samenleving enorm hoog is, is het slaagpercentage vaak frustrerend laag. In een vroeg stadium aarzelt de private sector om zich te engageren omdat het risico te groot is. Industrie spelers dringen aan op robuuste target validatie, d.w.z. bewijs dat het moduleren van specifieke targets tot gunstige effecten zal leiden. Aan de andere kant hebben bedrijven vaak niet de diepgaande expertise in de biologie zoals VIB.</p></div> </div> <div class="block block--layout-builder block--inline-blockimage-with-text media-position--right media-width--one-third has-text" id="image-with-text-444"> <div class="layout"> <div class="layout__item layout__item-image aos-init" data-aos=fade-left> <a class="non-crop-lightbox" href="/sites/vib.sites.vib.be/files/styles/max_1200x1400/public/2022-05/infographic_discoverySciences_drugAgroDiscovery.png.webp?itok=PBYJglek" data-lightbox="161"> <div class="primary-bg svg-wrapper"> <svg class="icon icon--search"> <use xlink:href="#icon--search"></use> </svg> </div> <picture> <source srcset="/sites/vib.sites.vib.be/files/styles/max_width_950/public/2022-05/infographic_discoverySciences_drugAgroDiscovery.png.webp?itok=Mmu_0hcS 1x, /sites/vib.sites.vib.be/files/styles/max_width_950_x2/public/2022-05/infographic_discoverySciences_drugAgroDiscovery.png.webp?itok=snRsSmHE 2x" media="(min-width: 768px)" type="image/webp" width="800" height="416"/> <source srcset="/sites/vib.sites.vib.be/files/styles/max_width_700/public/2022-05/infographic_discoverySciences_drugAgroDiscovery.png.webp?itok=0L7O-m4I 1x, /sites/vib.sites.vib.be/files/styles/max_width_700_x2/public/2022-05/infographic_discoverySciences_drugAgroDiscovery.png.webp?itok=fTZIxVWu 2x" media="(min-width: 0px)" type="image/webp" width="700" height="364"/> <img src="/sites/vib.sites.vib.be/files/styles/max_width_700/public/2022-05/infographic_discoverySciences_drugAgroDiscovery.png.webp?itok=0L7O-m4I" alt="" /> </picture> </a> </div> <div class="layout__item layout__item-text aos-init" data-aos=fade-right> <h2 class="field field--name-field-title field--type-string title field__item">Het faciliteren van nieuwe geneesmiddelen en landbouwproducten</h2> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>Het VIB Discovery Sciences team stelt specifieke expertise ter beschikking aan veelbelovende projecten in VIB labo's die zich lenen tot translatie.</p> <p>Met andere woorden, VIB Discovery Sciences initieert en begeleidt de transformatie van wetenschappelijke inzichten in projecten die nieuwe therapie毛n of landbouwproducten kunnen opleveren.</p></div> </div> </div> </div> <div class="block block--layout-builder block--inline-blockimage-with-text media-position--left media-width--fifty-fifty has-text" id="image-with-text-70b"> <div class="layout"> <div class="layout__item layout__item-image aos-init" data-aos=fade-right> <a class="non-crop-lightbox" href="/sites/vib.sites.vib.be/files/styles/max_1200x1400/public/2022-05/infographic_discoverySciences_partnering.png.webp?itok=_zUew1dz" data-lightbox="162"> <div class="primary-bg svg-wrapper"> <svg class="icon icon--search"> <use xlink:href="#icon--search"></use> </svg> </div> <picture> <source srcset="/sites/vib.sites.vib.be/files/styles/max_width_950/public/2022-05/infographic_discoverySciences_partnering.png.webp?itok=tJMqecCw 1x, /sites/vib.sites.vib.be/files/styles/max_width_950_x2/public/2022-05/infographic_discoverySciences_partnering.png.webp?itok=aVdz_FkP 2x" media="(min-width: 768px)" type="image/webp" width="800" height="516"/> <source srcset="/sites/vib.sites.vib.be/files/styles/max_width_700/public/2022-05/infographic_discoverySciences_partnering.png.webp?itok=cSrUZ-uS 1x, /sites/vib.sites.vib.be/files/styles/max_width_700_x2/public/2022-05/infographic_discoverySciences_partnering.png.webp?itok=3scLyAtF 2x" media="(min-width: 0px)" type="image/webp" width="700" height="452"/> <img src="/sites/vib.sites.vib.be/files/styles/max_width_700/public/2022-05/infographic_discoverySciences_partnering.png.webp?itok=cSrUZ-uS" alt="" /> </picture> </a> </div> <div class="layout__item layout__item-text aos-init" data-aos=fade-left> <h2 class="field field--name-field-title field--type-string title field__item">Samenwerken</h2> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>VIB Discovery Sciences bestaat uit een doorgewinterd team wetenschappers en technici met ervaring in de industrie en aanzienlijke expertise in verschillende aspecten van translationeel onderzoek. Het team is volledig ge茂ntegreerd in het Innovation & Business team van VIB en assisteert bij de uitwerking en uitvoering van translationele projecten.</p> <p>Het team gaat proactief te werk en begint aan het translationele werk na een valorisatieanalyse door de Innovation & Business unit.</p> <p>Een nauwe samenwerking met de PI, de VIB Core Facilities en externe partners met aanvullende expertise zijn daarbij van essentieel belang.</p> <p>Bij VIB streven we ernaar om in te spelen op onvervulde maatschappelijke noden en zoeken we hiervoor non-profitpartners zoals liefdadigheidsinstellingen. Op die manier tracht VIB Discovery Sciences projecten vooruit te helpen die tegemoetkomen aan kritieke onvervulde behoeften waar te weinig aandacht aan wordt geschonken door de industrie.</p></div> </div> </div> </div> <div class="block block--layout-builder block--inline-blocktext-one-col aos-init" data-aos=fade-down id="text-one-col-49b"> <h2 class="field field--name-field-title field--type-string title field__item">Derisking</h2> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>Het VIB Discovery Sciences team bedenkt en plant vroege projecten voor het ontwikkelen van geneesmiddelen en landbouwproducten, voert <em>in vitro</em> assayontwikkeling uit en ontwerpt en optimaliseert biologics en kleine moleculen. Ze nemen het projectbeheer voor hun rekening, werken samen met partners met complementaire expertise, en ontwerpen proof-of-concept studies voor nieuwe kandidaat-producten. Bovendien overlegt het team met het bredere VIB ecosysteem over verschillende aspecten van de ontwikkeling van geneesmiddelen en landbouwproducten. De targets en concepten worden volgens industriestandaarden ge毛valueerd.</p></div> </div> <div class="block block--layout-builder block--inline-blocktext-two-col" id="text-two-col-b6f"> <div class="layout aos-init" data-aos=fade-right> <div class="layout__item"> <h2 class="field field--name-field-title field--type-string title field__item">Succesverhalen</h2> </div> </div> <div class="layout"> <div class="layout__item layout__item-text aos-init" data-aos=fade-right> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>Oncurious - In 2015 richtte VIB samen met Oxurion Oncurious op. Deze spin-off richt zich op de ontwikkeling van innovatieve kankerbehandelingen. Het portfolio van Oncurious is gebaseerd op het preklinisch onderzoek van de VIB teams van Peter Carmeliet, Massimiliano Mazzone, Gabriele Bergers, en Jo Van Ginderachter. VIB Discovery Sciences heeft de leiding over de preklinische ontwikkeling van de nieuwe immuno-oncologische therapie毛n van de spin-off.</p> </div> <div class="field field--name-field-link field--type-link field--label-hidden btn-wrapper field__item"> <a href="https://www.oncurious.com/" class="btn btn--dark btn--invert">Oncurious</a> </div> </div> <div class="layout__item layout__item-text aos-init" data-aos=fade-left> <div class="clearfix text-formatted field field--name-field-text-two field--type-text-long field--label-hidden field__item"><p>Augustine Therapeutics - Een project om nieuwe geneesmiddelen te ontdekken voor de ziekte van Charcot-Marie-Tooth (CMT), gebaseerd op het onderzoek van Ludo Van Den Bosch, Joris de Wit, en Bart De Strooper. CMT wordt gekenmerkt door de progressieve denervatie van spieren en treft eerst de ledematen. Er zijn momenteel geen specifieke therapie毛n beschikbaar voor deze neurologische aandoening.</p> </div> <div class="field field--name-field-link-two field--type-link field--label-hidden btn-wrapper field__item"> <a href="https://www.augustinetx.com/" class="btn btn--dark btn--invert">Augustine Therapeutics</a> </div> </div> </div> </div> <div class="block block--layout-builder block--inline-blocktext-one-col aos-init" id="text-one-col-745"> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>De afgelopen jaren hebben de VIB wetenschappers verschillende biologische processen ontdekt in perifere neuropathie毛n die mogelijks veelbelovende therapeutische targets zijn voor CMT. VIB Discovery Sciences tracht het project nu tot in de preklinische fase te krijgen om nieuwe therapie毛n te ontwikkelen op basis van die nieuwe targets. Bovendien was het team in staat om externe financiering aan te trekken, waardoor het project aanzienlijk kan worden versneld.</p> </div> </div> <div class="block block--layout-builder block--inline-blocktext-one-col aos-init" data-aos=fade-down id="text-one-col-289"> <h2 class="field field--name-field-title field--type-string title field__item">Oefenterrein</h2> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>Daarnaast doet VIB Discovery Sciences dienst als oefenterrein voor jonge wetenschappers die de overstap willen maken naar de industrie. Pas-afgestudeerde doctoraatsstudenten leren wat een goede target is voor geneesmiddelenontwikkeling, welke aspecten relevant zijn bij de evaluatie van een nieuwe target, wat de grootste risico's zijn, en welke experimenten nodig zijn om die onzekerheden weg te werken. Om dit trainingsaspect verder te versterken heeft de afdeling Innovatie & Business nu ook een <a href="/node/16903">stageprogramma</a> gelanceerd. Hierbij gaan de stagiairs aan de slag in de verschillende afdelingen, waaronder het VIB Discovery Sciences team.</p></div> <div class="field field--name-field-link field--type-link field--label-hidden btn-wrapper field__item"> <a href="/nl/business/discovery-sciences/stageprogramma" class="btn btn--dark btn--invert">Stageprogramma</a> </div> </div> <div class="block block--layout-builder block--inline-blockquotes has-no-image primary-bg has-full-width-bg bg-primary bg-light-text" id="quotes-6dc"> <div class="field field--name-field-quote field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--quote paragraph--view-mode--default" id="quote-ec0"> <div class="field field--name-field-quote field--type-string-long field--label-hidden field__items"> <div class="field__item">In het VIB Discovery Sciences team krijg je de kans om nauw samen te werken met experts die veel ervaring hebben in de biotechsector en die je een inkijk geven in de wereld van antilichamen, nanobodies庐, recombinante eiwitten en kleine moleculen. Ik leer enorm veel bij op het vlak van strategisch denken, targets en farmacokinetiek. Je krijgt veel verantwoordelijkheid over je projecten, ontwikkelt tijdlijnen, bepaalt mijlpalen en werkt samen met CRO's en partners.</div> </div> <div class="person-wrapper"> <div class="blazy blazy--field blazy--field-image blazy--field-image--default field field--name-field-image field--type-entity-reference field--label-hidden field__item" data-blazy=""> <div data-b-token="b-c466441c727" class="media media--blazy media--bundle--image media--image is-b-loading"><img alt="Isabelle Cambr茅" decoding="async" class="media__element b-lazy" loading="lazy" data-src="/sites/vib.sites.vib.be/files/styles/thumbnail_square/public/2022-05/IsabelleCambre.png.webp?itok=vGtgGaSa" src="data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E" width="100" height="100" /> </div> </div> <div class="credentials"> <div class="field field--name-field-name field--type-string field--label-hidden field__item">Isabelle Cambr茅</div> <div class="field field--name-field-function field--type-string field--label-hidden field__item">wetenschapper bij VIB Discovery Sciences</div> </div> </div> </div> </div> </div> <div class="block block--layout-builder block--inline-blockquotes has-no-image primary-bg has-full-width-bg bg-primary bg-light-text background primary-bg no-overlay"> </div> </div> <div class="block block--layout-builder block--inline-blocklocations" id="locations-1ce"> <div class="field field--name-field-locations field--type-entity-reference-revisions field--label-hidden field__item"><div class="views-element-container"> <div class="view view--locations view--locations--map view-display-id-map js-view-dom-id-d77b96224f16d61bd19951bb218cf666925cc36bd285a9c5152e95719c1697dd"> <div class="attachment attachment-before location-list"> <div class="views-element-container"> <div class="view view--locations view--locations--locations_list view-display-id-locations_list js-view-dom-id-8ccf7eaf4048b940a94d77bdcb1bac4d3f94d8db2e6b0ff082ebb5f29f12f364"> <div class="view-content aos-init" data-aos="fade-left"> <div class="views-row"> <div><h2>VIB's Discovery Sciences team - Gent</h2></div><div class="views-field views-field-rendered-entity"><span class="field-content"> <div class="paragraph paragraph--type--location paragraph--view-mode--default" id="location-e1a"> <div class="field field--name-field-location-address field--type-address field--label-hidden field__item"><p class="address" translate="no"><span class="organization">VIB</span><br> <span class="address-line1">Technologiepark-Zwijnaarde 104</span><br> <span class="postal-code">9052</span> <span class="locality">Gent</span><br> <span class="country">Belgi毛</span></p></div> <div class="field field--name-field-phone-number field--type-telephone field--label-hidden field__item"><a href="tel:%2B3292610631">+32 9 2610631</a></div> <div class="field field--name-field-email field--type-email field--label-hidden field__item"><a href="mailto:contactVDS@vib.be">contactVDS@vib.be</a></div> </div> </span></div> </div> </div> </div> </div> </div> <div class="view-content location-map"> <div id="leaflet-map-view-locations-map" style="min-width: 150px; height: 400px"></div> </div> </div> </div> </div> </div> <div class="block block--layout-builder block--inline-blocklocations" id="locations-43e"> <div class="field field--name-field-locations field--type-entity-reference-revisions field--label-hidden field__item"><div class="views-element-container"> <div class="view view--locations view--locations--map view-display-id-map js-view-dom-id-dd002370f36984446147f7e746dfb65060cd653edf4999aada72e945deaf3863"> <div class="attachment attachment-before location-list"> <div class="views-element-container"> <div class="view view--locations view--locations--locations_list view-display-id-locations_list js-view-dom-id-c6f64280b9528c367618f1d8b4c2c73fe89badfc343a92f065b0a93f5a9e8a7e"> <div class="view-content aos-init" data-aos="fade-left"> <div class="views-row"> <div><h2>VIB's Discovery Sciences team - Leuven</h2></div><div class="views-field views-field-rendered-entity"><span class="field-content"> <div class="paragraph paragraph--type--location paragraph--view-mode--default" id="location-f7c"> <div class="field field--name-field-location-address field--type-address field--label-hidden field__item"><p class="address" translate="no"><span class="organization">VIB</span><br> <span class="address-line1">Gaston Geenslaan 1</span><br> <span class="postal-code">3001</span> <span class="locality">Leuven</span><br> <span class="country">Belgi毛</span></p></div> <div class="field field--name-field-phone-number field--type-telephone field--label-hidden field__item"><a href="tel:%2B3216852660">+32 16 852660</a></div> <div class="field field--name-field-email field--type-email field--label-hidden field__item"><a href="mailto:contactVDS@vib.be">contactVDS@vib.be</a></div> </div> </span></div> </div> </div> </div> </div> </div> <div class="view-content location-map"> <div id="leaflet-map-view-locations-map--2" style="min-width: 150px; 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input.classList.remove("phone-input-error"); }; var initializePhoneInput = function(input, defaultCountry) { return window.intlTelInput(input, { utilsScript: "https://unpkg.com/intl-tel-input@17.0.18/build/js/utils.js", autoHideDialCode: false, separateDialCode: true, initialCountry: defaultCountry, preferredCountries: [] }); } var setPhoneInputEventListeners = function(inputId, input, iti) { input.addEventListener('blur', function() { var errorMessage = document.getElementById("error-msg-" + inputId); if (input.value.trim()) { if (iti.isValidNumber()) { iti.setNumber(iti.getNumber()); if (errorMessage.classList.contains("phone-error")){ hidePhoneInputError(inputId); } } else { showPhoneInputError(inputId) } } else { if (errorMessage.classList.contains("phone-error")){ hidePhoneInputError(inputId); } } }); input.addEventListener("countrychange", function() { iti.setNumber(''); }); input.addEventListener("keydown", function(e) { var charCode = (e.which) ? e.which : e.keyCode; if (charCode > 31 && (charCode < 48 || charCode > 57) && charCode !== 8) { e.preventDefault(); } }); }; var showPhoneInputError = function(inputId) { var errorMessage = document.getElementById("error-msg-" + inputId); var input = document.getElementById(inputId); errorMessage.classList.add("phone-error"); errorMessage.classList.remove("phone-error-hidden"); input.classList.add("phone-input-error"); }; window['recaptcha_callback'] = function() { // Get all recaptchas in the DOM (there may be more than one form on the page). var recaptchas = document.getElementsByClassName("g-recaptcha"); for (var i in recaptchas) { // Set the recaptcha element ID, so the recaptcha can be applied to each element. var recaptcha_id = "recaptcha_" + i; recaptchas[i].id = recaptcha_id; var el = document.getElementById(recaptcha_id); if (el != null) { var sitekey = el.getAttribute("data-sitekey"); var stoken = el.getAttribute("data-stoken"); grecaptcha.render(recaptcha_id, {"sitekey":sitekey,"stoken":stoken}); } } }; _load_script("https://www.google.com/recaptcha/api.js?onload=recaptcha_callback&render=explicit"); var _form_serialize = function(form){if(!form||form.nodeName!=="FORM"){return }var i,j,q=[];for(i=0;i<form.elements.length;i++){if(form.elements[i].name===""){continue}switch(form.elements[i].nodeName){case"INPUT":switch(form.elements[i].type){case"tel":q.push(form.elements[i].name+"="+encodeURIComponent(form.elements[i].previousSibling.querySelector('div.iti__selected-dial-code').innerText)+encodeURIComponent(" 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q.join("&")}; var form_submit = function(e) { e.preventDefault(); if (validate_form()) { // use this trick to get the submit button & disable it using plain javascript document.querySelector('#_form_9_submit').disabled = true; var serialized = _form_serialize(document.getElementById('_form_9_')).replace(/%0A/g, '\\n'); var err = form_to_submit.querySelector('._form_error'); err ? err.parentNode.removeChild(err) : false; _load_script('https://vib.activehosted.com/proc.php?' + serialized + '&jsonp=true'); } return false; }; addEvent(form_to_submit, 'submit', form_submit); })(); </script> </div> </div> </div> </div> </div> </div> </section> <section class="footer"> <div class="region__inner"> <div class="footer__content"> <div class="region region--footer-top"> <div class="region__inner"> <div class="block block--system block--system-breadcrumb-block" id="block-system-breadcrumb-block" id=""> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"><h2 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