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(PDF) Optimizing Tubular Centrifuges for Fine Particle Separation
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[{"id":40563612,"identifier":"Attachment_40563612","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":19335921,"created_at":"2015-12-01T23:18:09.833-08:00","from_world_paper_id":145460875,"updated_at":"2025-02-01T13:38:46.369-08:00","_data":{"ai_title_tag":"Optimizing Tubular Centrifuges for Fine Particle Separation","grobid_abstract":"The demand for instruments that are suitable for the separation of fine particles and biological cells is steadily increasing. Various innovative particles have already implemented in bulk products and many others are close to commercial availability. Tubular bowl centrifuges offer high centrifugal forces at reasonable throughputs. There is a high potential for the optimisation of existing processes and in the design of new tubular centrifuges especially for the separation of nanoscale materials. The separation of fine particulates and biological cells in a semibatch tubular bowl centrifuge at high rotational speeds is described in this work. Furthermore, the influence of the sediment on the process outcome and possibilities to enhance the separation efficiency were investigated. A boundary layer flow was indirectly detected. Structures inside the rotor of the centrifuge cause defined liquid flow patterns, which influence the separation efficiency. A comparison of the separation behaviour with an unimpaired flow and the redirected flow yielded conclusions about the actual flow patterns.","publication_date":"2010,,","publication_name":"Chemical Engineering Science","grobid_abstract_attachment_id":"40563612"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Processing of dispersions containing fine particles or biological products in tubular bowl centrifuges","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [39599176]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loginModal = {}; window.loginModal.appleClientId = 'edu.academia.applesignon'; window.userInChina = "false";</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":40563612,"attachmentType":"pdf"}"><img alt="First page of “Processing of dispersions containing fine particles or biological products in tubular bowl centrifuges”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/40563612/mini_magick20190220-16283-1o6i4pu.png?1550723222" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/images/single_work_splash/adobe_icon.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Processing of dispersions containing fine particles or biological products in tubular bowl centrifuges</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="39599176" href="https://kit.academia.edu/HermannNirschl"><img alt="Profile image of Hermann Nirschl" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Hermann Nirschl</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2010, Chemical Engineering Science</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">9 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 19335921; const worksViewsPath = "/v0/works/views?subdomain_param=api&work_ids%5B%5D=19335921"; const getWorkViews = async (workId) => { const response = await fetch(worksViewsPath); if (!response.ok) { throw new Error('Failed to load work views'); } const data = await response.json(); return data.views[workId]; }; // Get the view count for the work - we send this immediately rather than waiting for // the DOM to load, so it can be available as soon as possible (but without holding up // the backend or other resource requests, because it's a bit expensive and not critical). const viewCount = await getWorkViews(workId); const updateViewCount = (viewCount) => { try { const viewCountNumber = parseInt(viewCount, 10); if (viewCountNumber === 0) { // Remove the whole views element if there are zero views. document.getElementById('work-metadata-view-count')?.parentNode?.remove(); return; } const commaizedViewCount = viewCountNumber.toLocaleString(); const viewCountBody = document.getElementById('work-metadata-view-count'); if (!viewCountBody) { throw new Error('Failed to find work views element'); } viewCountBody.textContent = `${commaizedViewCount} views`; } catch (error) { // Remove the whole views element if there was some issue parsing. document.getElementById('work-metadata-view-count')?.parentNode?.remove(); throw new Error(`Failed to parse view count: ${viewCount}`, error); } }; // If the DOM is still loading, wait for it to be ready before updating the view count. if (document.readyState === "loading") { document.addEventListener('DOMContentLoaded', () => { updateViewCount(viewCount); }); // Otherwise, just update it immediately. } else { updateViewCount(viewCount); } })();</script></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">The demand for instruments that are suitable for the separation of fine particles and biological cells is steadily increasing. Various innovative particles have already implemented in bulk products and many others are close to commercial availability. Tubular bowl centrifuges offer high centrifugal forces at reasonable throughputs. There is a high potential for the optimisation of existing processes and in the design of new tubular centrifuges especially for the separation of nanoscale materials. The separation of fine particulates and biological cells in a semibatch tubular bowl centrifuge at high rotational speeds is described in this work. Furthermore, the influence of the sediment on the process outcome and possibilities to enhance the separation efficiency were investigated. A boundary layer flow was indirectly detected. Structures inside the rotor of the centrifuge cause defined liquid flow patterns, which influence the separation efficiency. A comparison of the separation behaviour with an unimpaired flow and the redirected flow yielded conclusions about the actual flow patterns.</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":40563612,"attachmentType":"pdf","workUrl":"https://www.academia.edu/19335921/Processing_of_dispersions_containing_fine_particles_or_biological_products_in_tubular_bowl_centrifuges"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":40563612,"attachmentType":"pdf","workUrl":"https://www.academia.edu/19335921/Processing_of_dispersions_containing_fine_particles_or_biological_products_in_tubular_bowl_centrifuges"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div><div class="ds-signup-banner-trigger-container"><div class="ds-signup-banner-trigger ds-signup-banner-trigger-control"></div></div><div class="ds-signup-banner ds-signup-banner-control"><div id="ds-signup-banner-close-button"><button class="ds2-5-button ds2-5-button--secondary ds2-5-button--inverse"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">close</span></button></div><div class="ds-signup-banner-ctas"><img src="//a.academia-assets.com/images/academia-logo-capital-white.svg" /><h4 class="ds2-5-heading-serif-sm">Sign up for access to the world's latest research</h4><button class="ds2-5-button ds2-5-button--inverse ds2-5-button--full-width js-swp-download-button" data-signup-modal="{"location":"signup-banner"}">Sign up for free<span class="material-symbols-outlined" style="font-size: 20px" translate="no">arrow_forward</span></button></div><div class="ds-signup-banner-divider"></div><div class="ds-signup-banner-reasons"><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Get notified about relevant papers</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Save papers to use in your research</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Join the discussion with peers</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Track your impact</span></div></div></div><script>(() => { // Set up signup banner show/hide behavior: // 1. 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On the other hand, inertial microfluidics (spiral and multi-orifice) showed various advantages such as simple design and fabrication, the ability to process large sample volume, high throughput, high recovery rate, and the ability for multiplexing for improved performance. However, the utilization of syringe pump can reduce the portability options of the platform. In conclusion, the requirement of each application should be carefully considered prior to platform selection.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Particle/cell separation on microfluidic platforms based on centrifugation effect: a review","attachmentId":113272604,"attachmentType":"pdf","work_url":"https://www.academia.edu/117407578/Particle_cell_separation_on_microfluidic_platforms_based_on_centrifugation_effect_a_review","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/117407578/Particle_cell_separation_on_microfluidic_platforms_based_on_centrifugation_effect_a_review"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="44788588" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/44788588/Centrifugation_Separation">Centrifugation Separation</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="179043118" href="https://independent.academia.edu/HendAhmed76">Hend A Abdelfatah</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="180374028" href="https://independent.academia.edu/SZwaid">Safaa Zwaid</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Research Paper , 2020</p><p class="ds-related-work--abstract ds2-5-body-sm">It is well known that the world suffers from many grand challenges that hinder its wheel of development. water pollution is a serious challenge facing it because of Widely spreading microplastics. The problem with microplastics is that they do not disappear in the environment, Plastic takes an extremely long time to degrade completely and during this long period, these particles of different sizes risk causing harm to a variety of organisms including humans. This study will decrease the number of microplastics in drinking water and prevent many diseases from spreading through it. The proposed idea is to utilize the centrifugal force technique in a simple machine that looks like a washing machine in the internal structure, it will apply at the bottom of a ship to purify water from microplastics. After the prototype was tested, the results showed the prototype fulfilled the design requirements of Cost reduction and efficiency preservation as the prototype efficiency is 99.75%. The project also proved to be safe for the marine creature and ready to be used. In conclusion, the project is valid and offers the world a huge opportunity to decrease water pollution. Key words: Microplastics -Centrifugal force-pollution</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Centrifugation Separation","attachmentId":65283583,"attachmentType":"pdf","work_url":"https://www.academia.edu/44788588/Centrifugation_Separation","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/44788588/Centrifugation_Separation"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="23540735" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23540735/Microfluidic_centrifuge_of_nano_particles_using_rotating_flow_in_a_microchamber">Microfluidic centrifuge of nano-particles using rotating flow in a microchamber</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="45563590" href="https://independent.academia.edu/ShinBoSung">Bo-Sung Shin</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="45580415" href="https://independent.academia.edu/JHa11">J. Ha</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2008</p><p class="ds-related-work--abstract ds2-5-body-sm">This paper presents the centrifugation of the nano-particles using the rotating flow in the microchamber. The feasibility of the microfluidic centrifuge was demonstrated numerically and experimentally. The centrifugation of the nano-particles of 300 and 500 nm was visualized by using a high-speed CCD camera and a micro-PIV. In addition, its performance was characterized quantitatively. The experimental results of the mechanical contact-free microfluidic centrifuge showed the same physical phenomena with the conventional one even in its small size. Also, a new finding was obtained that the transient motion influenced the stable operation of the microfluidic centrifuge.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Microfluidic centrifuge of nano-particles using rotating flow in a microchamber","attachmentId":43970968,"attachmentType":"pdf","work_url":"https://www.academia.edu/23540735/Microfluidic_centrifuge_of_nano_particles_using_rotating_flow_in_a_microchamber","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23540735/Microfluidic_centrifuge_of_nano_particles_using_rotating_flow_in_a_microchamber"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="27995503" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/27995503/Encyclopedia_of_separation_science_CENTRIFUGATION">Encyclopedia of separation science-CENTRIFUGATION</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="52495583" href="https://independent.academia.edu/cgarzillo">carmine garzillo</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Encyclopedia of separation science-CENTRIFUGATION","attachmentId":48301535,"attachmentType":"pdf","work_url":"https://www.academia.edu/27995503/Encyclopedia_of_separation_science_CENTRIFUGATION","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/27995503/Encyclopedia_of_separation_science_CENTRIFUGATION"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="53208464" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/53208464/Mechanism_of_centrifugal_filtration_for_separation_of_microbe_protein_bio_suspension">Mechanism of centrifugal filtration for separation of microbe/protein bio-suspension</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="87201738" href="https://independent.academia.edu/YiangChenChou">Yiang-Chen Chou</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Chemical Engineering and Processing: Process Intensification, 2008</p><p class="ds-related-work--abstract ds2-5-body-sm">The mechanism of centrifugal filtration of microbe/protein bio-suspension is studied. The bio-suspension is prepared by adding baker yeast and albumin bovine serum (BSA) into a buffer solution at pH 7.0; and the BSA molecules are purified from the mixture in a swing-arm centrifuge under rotational speeds ranging from 500 to 4000 rpm. A numerical program is established for estimating the concentration profiles of yeast cells in the filter chamber, the cake growth rate, the cake properties and filtration rate. The variations of the average specific filtration resistance and average porosity of cake are estimated based on a Voigt-in-series compression model. The simulated results of cake properties and filtrate rate agree fairly well with the available experimental data. In addition, the separation efficiency of BSA can be predicted accurately under various conditions once the BSA permeation through the cake and the filter septum is analyzed. To compare the separation efficiency of BSA in the centrifugal and cross-flow microfiltration systems, use of centrifugal filtration with a centrifugal effect just over the critical value is an optimum on the viewpoint of operating time, separation efficiency, and energy-saving.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Mechanism of centrifugal filtration for separation of microbe/protein bio-suspension","attachmentId":70105194,"attachmentType":"pdf","work_url":"https://www.academia.edu/53208464/Mechanism_of_centrifugal_filtration_for_separation_of_microbe_protein_bio_suspension","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/53208464/Mechanism_of_centrifugal_filtration_for_separation_of_microbe_protein_bio_suspension"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="109660809" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/109660809/Centrifugal_nanofiltration_for_small_volume_samples">Centrifugal nanofiltration for small-volume samples</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="17745727" href="https://lisboa.academia.edu/CarlosCompleto">Carlos Completo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Membrane Science, 2017</p><p class="ds-related-work--abstract ds2-5-body-sm">The concentration of small-volume samples containing substances with molecular weight below 1 kDa is usually done by expensive and tedious techniques, and, for this reason it is important to develop expedite and low cost methods. In this work we designed, manufactured and tested an innovative laboratorial centrifugal nanofiltration (CNF) device that accomplishes those targets. The influence of operational parameters on the CNF device performance was comprehensively evaluated, including the effects of: rotational speed, solute type, solute concentration, height of the filtration chamber and angle between the centrifugal force and the membrane surface. Using the developed device to nanofilter three model solute solutions (potassium sulfate, sucrose and polyethylene glycol) we were able to obtain concentration factors higher than 20, reducing the sample volume from 3.2 mL to less than 100 µL of concentrate. Experimental data suggest that the performance obtained is better for negative angles resulting in the disruption of the concentration polarization layer, whereas should lie between 0.2 mm and 0.6 mm. The CNF device proved to be a consistent technique to attain the nanofiltration of small-volume samples for further processing or analysis.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Centrifugal nanofiltration for small-volume samples","attachmentId":107719081,"attachmentType":"pdf","work_url":"https://www.academia.edu/109660809/Centrifugal_nanofiltration_for_small_volume_samples","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/109660809/Centrifugal_nanofiltration_for_small_volume_samples"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="104166386" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/104166386/Further_Development_of_a_Centrifugal_Solids_Separator_Prototype">Further Development of a Centrifugal Solids Separator Prototype</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="254016113" href="https://independent.academia.edu/REYNOSOPRISCILA">PRISCILA REYNOSO</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2016</p><p class="ds-related-work--abstract ds2-5-body-sm">This thesis was made for SansOx Ltd, part of the Finnish Cleantech cluster of companies, whose innovative ideas in the water treatment area have been awarded the WssTP Water Innovation SME Award for two consecutive years. The purpose of the thesis was to make a deeper theoretical research of the physical aspects related to solids separation in one of SansOx's innovations, a centrifugal solids separation device. Based on this research, it was aimed to make a review of the previous tests of the pilot-scale prototypes of the device as well as to develop a plan that would be the base for testing a prototype in a laboratory-scale. The theory of solids separation in the device is strongly linked to hydraulics and particle settling, so the theoretical research was divided into three main subjects: physics and hydraulics, particle separation, and solid separation methods. Some basic principles of physics, such as vectors and forces, are the base for explaining the hydraulics related to fluid flow through pipes as well as for explaining the basic theory of particle settling. Solids separation methods were studied for a comparison between the commonly used methods in water treatment and SansOx's device. With the information of the theoretical research, a review of the conditions of the previous tests of the prototype could be made, as well as finding a cause for the results obtained in the tests. Lastly, the same calculations were used to develop the sizing and testing plan of a laboratory-scale prototype. The results of the calculations showed that the main challenge in the previous testing of the prototypes was to achieve a discharge that would be high enough for separation. The parameters and calculations related to the solids separation were gathered into one single Excel workbook that would serve as a tool for designing a prototype depending on the characteristics of the solution to be treated. Finally, with this tool, a plan for the laboratory-scale prototype was developed.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Further Development of a Centrifugal Solids Separator Prototype","attachmentId":103964761,"attachmentType":"pdf","work_url":"https://www.academia.edu/104166386/Further_Development_of_a_Centrifugal_Solids_Separator_Prototype","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/104166386/Further_Development_of_a_Centrifugal_Solids_Separator_Prototype"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="19353536" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/19353536/2_dimensional_separation_of_biomimetic_particles_by_stopped_flow_centrifugo_magnetophoresis">2-dimensional separation of biomimetic particles by stopped-flow centrifugo-magnetophoresis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39540712" href="https://dcu.academia.edu/JensDucr%C3%A9e">Jens Ducrée</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, 2011</p><p class="ds-related-work--abstract ds2-5-body-sm">This paper presents a centrifugo-magnetophoretic principle for the 2-dimensional separation of particles towards cell separation applications. Multi-force particle separation is achieved through the favorable combination of centrifugal sedimentation and magnetic deflection, while a stopped-flow mode (i.e., no fluid flow, mere sedimentation) is implemented to minimize divergent flow-lines and hydrodynamic instabilities typical in pressure-driven microfluidic platforms. The results demonstrate immuno-capture of biomimetic elements by magnetic particles and subsequent routing of these particle tandems to a designated outlet. During separation, shear stresses and forces that can unfavorably alter biological cells are reduced as compared to more common pressure-driven systems. Hence, the novel, stopped-flow, centrifugo-magnetophoretic separation system enables a possible post-separation analysis of mechanically undisturbed cells.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"2-dimensional separation of biomimetic particles by stopped-flow centrifugo-magnetophoresis","attachmentId":40573809,"attachmentType":"pdf","work_url":"https://www.academia.edu/19353536/2_dimensional_separation_of_biomimetic_particles_by_stopped_flow_centrifugo_magnetophoresis","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/19353536/2_dimensional_separation_of_biomimetic_particles_by_stopped_flow_centrifugo_magnetophoresis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="27761793" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/27761793/Fluid_dynamic_analysis_of_the_solid_liquid_separation_process_by_centrifugation">Fluid dynamic analysis of the solid-liquid separation process by centrifugation</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="47558748" href="https://poliba.academia.edu/RiccardoAmirante">Riccardo Amirante</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="52089173" href="https://independent.academia.edu/CatalanoP">P. Catalano</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Agricultural Engineering Research</p><p class="ds-related-work--abstract ds2-5-body-sm">In this paper, a theoretical analysis and preliminary experimental trials of the solid}liquid separation process by centrifugation has been carried out to evaluate the modi"cations which would improve the performance of the centrifuge.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Fluid dynamic analysis of the solid-liquid separation process by centrifugation","attachmentId":48038673,"attachmentType":"pdf","work_url":"https://www.academia.edu/27761793/Fluid_dynamic_analysis_of_the_solid_liquid_separation_process_by_centrifugation","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/27761793/Fluid_dynamic_analysis_of_the_solid_liquid_separation_process_by_centrifugation"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="19000367" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/19000367/Decanter_centrifugal_machines_for_mixture_separation">Decanter centrifugal machines for mixture separation</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38009530" href="https://independent.academia.edu/TheodoreCostopoulos">Theodore Costopoulos</a></div><p class="ds-related-work--abstract ds2-5-body-sm">The Decanters are centrifugal machines used to separate mixtures of two or more liquid and solid constituents of different densities. In this paper the kinetic and dynamic analysis of these machines is presented, in order to determine the developed forces (needed for the separation of the input mixture) and the power flow paths through the different parts of the machine. The involved physical quantities are formulated into flexible functions, in order to make this modeling applicable to all types of decanters (wide variety of use and dimensions). This project comprises the base of a threefold optimization: a) the separation quality, b) the mixture's capacity and c) the design of the centrifugal machines. The separation chamber is formed by the shell containing the screw conveyor (to drive the constituents to the appropriate exits), for which the correct operation calls for a relative motion between the shell and the conveyor. This is possible by using a two-stage planetary mechanism. The planetary gearbox is of vital importance for the decanter and it is analyzed to determine a) the ratio of power between the inputs of the gearbox and b) the ratio of power between the chamber shell and the conveyor. Modeling of separation chamber is achieved by dividing the chamber into three compartments: a) the separation compartment (removal of the lighter constituents of the mixture) b) the cylindrical compartment (transfer of the heavier constituent) and c) the truncated-conical compartment (the drainage of the heavier constituent due to the continuous change of cross sectional area of the shell). It is concluded that the basic power in each compartment depends on : i) the quantity of the constituents which enter each compartment, ii) the geometry of the shell in each compartment, iii) the geometry of the screw conveyor in each compartment, iv) the nature of the mixture (coefficient of friction, viscosity), and v) the square of the peripheral velocity of both the conveyor and shell. Finally, for the cylindrical compartment it is notable that the ratio of the developed centrifugal force to the force of propulsion depends exclusively on the coefficient of friction of the solid constituent. Specifically, for low values of the coefficient of friction, this ratio increases linearly whereas for higher values the ratio increases non-linearly. Therefore, the maximum permissible coefficient of friction can be determined.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Decanter centrifugal machines for mixture separation","attachmentId":40733369,"attachmentType":"pdf","work_url":"https://www.academia.edu/19000367/Decanter_centrifugal_machines_for_mixture_separation","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/19000367/Decanter_centrifugal_machines_for_mixture_separation"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":40563612,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":40563612,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_40563612" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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js-related-work-grid-card-view-pdf" href="https://www.academia.edu/15668159/Centrifugo_magnetophoretic_separation_and_routing_of_particles"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="3" data-entity-id="19353413" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/19353413/Handling_and_analysis_of_cells_and_bioparticles_on_centrifugal_microfluidic_platforms">Handling and analysis of cells and bioparticles on centrifugal microfluidic platforms</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39540712" href="https://dcu.academia.edu/JensDucr%C3%A9e">Jens Ducrée</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Expert Review of Molecular Diagnostics, 2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Handling and analysis of cells and bioparticles on centrifugal microfluidic platforms","attachmentId":40573743,"attachmentType":"pdf","work_url":"https://www.academia.edu/19353413/Handling_and_analysis_of_cells_and_bioparticles_on_centrifugal_microfluidic_platforms","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/19353413/Handling_and_analysis_of_cells_and_bioparticles_on_centrifugal_microfluidic_platforms"><span 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class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="5" data-entity-id="51249919" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/51249919/Centrifugation_Techniques">Centrifugation Techniques</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="41903024" href="https://essex.academia.edu/DRickwood">David Rickwood</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Encyclopedia of Life Sciences, 2001</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Centrifugation 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