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Lupus erythematosus panniculitis - Wikipedia

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searchaux" style="display:none">Medical condition</div><style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox ib-medical-condition"><tbody><tr><th colspan="2" class="infobox-above" style="background:#ccc">Lupus erythematosus panniculitis</th></tr><tr><th scope="row" class="infobox-label">Other names</th><td class="infobox-data">Lupus erythematosus profundus,<sup id="cite_ref-Andrews_1-0" class="reference"><a href="#cite_note-Andrews-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Lupus panniculitis,<sup id="cite_ref-Bolognia_2-0" class="reference"><a href="#cite_note-Bolognia-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> "Lupus profundus",<sup id="cite_ref-Bolognia_2-1" class="reference"><a href="#cite_note-Bolognia-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> and Subcutaneous lupus erythematosus<sup id="cite_ref-Bolognia_2-2" class="reference"><a href="#cite_note-Bolognia-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Medical_specialty" title="Medical specialty">Specialty</a></th><td class="infobox-data"><a href="/wiki/Dermatology" title="Dermatology">Dermatology</a></td></tr></tbody></table> <style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">Not to be confused with <a href="/wiki/Subacute_cutaneous_lupus_erythematosus" title="Subacute cutaneous lupus erythematosus">Subacute cutaneous lupus erythematosus</a> or <a href="/wiki/Lupus_erythematosus" title="Lupus erythematosus">Lupus erythematosus</a>.</div> <p><b>Lupus erythematosus panniculitis</b> presents with subcutaneous <a href="/wiki/Nodule_(medicine)" title="Nodule (medicine)">nodules</a> that are commonly firm, sharply defined and nontender.<sup id="cite_ref-Andrews_1-1" class="reference"><a href="#cite_note-Andrews-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Signs_and_symptoms">Signs and symptoms</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=1" title="Edit section: Signs and symptoms"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Lupus erythematosus panniculitis consists of soft, deep subcutaneous plaques or <a href="/wiki/Nodule_(medicine)" title="Nodule (medicine)">nodules</a> that can occasionally appear in crops. Proximal extremities, in particular the lateral aspects of the arms and shoulders, face,&#160;trunk, buttocks&#160;breast,&#160;and scalp, are typically involved. Lesions can affect several areas at once or just one.<sup id="cite_ref-Fraga_2008_3-0" class="reference"><a href="#cite_note-Fraga_2008-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> Very few generalized forms exist.<sup id="cite_ref-deficiency_of_C4_4-0" class="reference"><a href="#cite_note-deficiency_of_C4-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup> There is a preference for the face in pediatric patients.<sup id="cite_ref-Cribier_2005_pp._243–248_5-0" class="reference"><a href="#cite_note-Cribier_2005_pp._243–248-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup> In cases of <a href="/wiki/Discoid_lupus_erythematosus" title="Discoid lupus erythematosus">discoid lupus erythematosus</a>, the skin surface may exhibit scaling, <a href="/wiki/Atrophy" title="Atrophy">atrophy</a>,&#160;follicular plugging, <a href="/wiki/Telangiectasia" title="Telangiectasia">telangiectasias</a>,&#160;<a href="/wiki/Depigmentation" title="Depigmentation">depigmentation</a>, or <a href="/wiki/Ulcer_(dermatology)" title="Ulcer (dermatology)">ulceration</a>. <a href="/wiki/Erythema" title="Erythema">Erythema</a> is a common clinical feature in the overlying skin.<sup id="cite_ref-a_case_series_6-0" class="reference"><a href="#cite_note-a_case_series-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup> The clinical course of lupus erythematosus panniculitis lesions is chronic and relapsing. There are areas of lipoatrophic depression left behind after the <a href="/wiki/Nodule_(medicine)" title="Nodule (medicine)">nodules</a> resolve.<sup id="cite_ref-Fraga_2008_3-1" class="reference"><a href="#cite_note-Fraga_2008-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Causes">Causes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=2" title="Edit section: Causes"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Lupus erythematosus panniculitis may manifest independently or in conjunction with <a href="/wiki/Discoid_lupus_erythematosus" title="Discoid lupus erythematosus">discoid lupus erythematosus</a> (DLE) or <a href="/wiki/Systemic_lupus_erythematosus" class="mw-redirect" title="Systemic lupus erythematosus">systemic lupus erythematosus</a> (SLE).<sup id="cite_ref-a_case_series_6-1" class="reference"><a href="#cite_note-a_case_series-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup> Lupus erythematosus panniculitis occurs independently twice as often as when combined with SLE or DLE.<sup id="cite_ref-personal_approach_7-0" class="reference"><a href="#cite_note-personal_approach-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Diagnosis">Diagnosis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=3" title="Edit section: Diagnosis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The gold standard for diagnosing a lesioned skin specimen is its <a href="/wiki/Histopathology" title="Histopathology">histopathological</a> examination.<sup id="cite_ref-on_a_patient_8-0" class="reference"><a href="#cite_note-on_a_patient-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup> Two authors have outlines a histopathologic diagnostic criteria for lupus erythematosus panniculitis. The major criteria includes calcification, periseptal or lobular lymphocytic <a href="/wiki/Panniculitis" title="Panniculitis">panniculitis</a>, <a href="/wiki/Lymphocyte" title="Lymphocyte">lymphocytic</a> aggregates and lymphoid follicle formation, and <a href="/wiki/Hyaline" title="Hyaline">hyaline</a> fat <a href="/wiki/Necrosis" title="Necrosis">necrosis</a>. The minor criteria includes <a href="/wiki/Discoid_lupus_erythematosus" title="Discoid lupus erythematosus">discoid lupus erythematosus</a> alterations in the skin layer above, lymphocytic vascular inflammation, subepidermal zone hyalinization, <a href="/wiki/Mucin" title="Mucin">mucin</a> deposition, <a href="/wiki/Histiocyte" title="Histiocyte">histiocytes</a> and tiny <a href="/wiki/Granuloma" title="Granuloma">granulomas</a>, and <a href="/wiki/Plasma_cell" title="Plasma cell">plasma cell</a> and <a href="/wiki/Eosinophil" title="Eosinophil">eosinophil</a> infiltrates.<sup id="cite_ref-Peters_Su_1991_pp._189–192_9-0" class="reference"><a href="#cite_note-Peters_Su_1991_pp._189–192-9"><span class="cite-bracket">&#91;</span>9<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Peters_Daniel_Su_1989_pp._1113–1126_10-0" class="reference"><a href="#cite_note-Peters_Daniel_Su_1989_pp._1113–1126-10"><span class="cite-bracket">&#91;</span>10<span class="cite-bracket">&#93;</span></a></sup> </p><p>Although serologic analyses are frequently normal, it is occasionally possible to show a positive <a href="/wiki/Antinuclear_antibody" title="Antinuclear antibody">antinuclear antibody</a> titer. Antibodies against <a href="/wiki/Double-stranded_DNA" class="mw-redirect" title="Double-stranded DNA">double-stranded DNA</a> are less common. The serology for <a href="/wiki/Syphilis" title="Syphilis">syphilis</a> may give a false positive.<sup id="cite_ref-Fraga_2008_3-2" class="reference"><a href="#cite_note-Fraga_2008-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> Anemia, lowered C4 levels, positive <a href="/wiki/Rheumatoid_factor" title="Rheumatoid factor">rheumatoid factor</a>, <a href="/wiki/Lymphopenia" class="mw-redirect" title="Lymphopenia">lymphopenia</a>, and <a href="/wiki/Anemia" title="Anemia">anemia</a> are additional potential abnormalities in the laboratory.<sup id="cite_ref-a_case_series_6-2" class="reference"><a href="#cite_note-a_case_series-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Outlook">Outlook</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=4" title="Edit section: Outlook"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Despite being regarded as a benign form of <a href="/wiki/Lupus_erythematosus" title="Lupus erythematosus">lupus erythematosus</a>,<sup id="cite_ref-case_reports_11-0" class="reference"><a href="#cite_note-case_reports-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup> lupus erythematosus panniculitis&#160;can occasionally cause significant morbidity due to the disease's damaging cosmetic effects and disability caused by painful lesions.<sup id="cite_ref-not_a_benign_disease_12-0" class="reference"><a href="#cite_note-not_a_benign_disease-12"><span class="cite-bracket">&#91;</span>12<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Treatment">Treatment</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=5" title="Edit section: Treatment"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Antimalarials" class="mw-redirect" title="Antimalarials">Antimalarials</a> are regarded as the traditional course of care and, for certain patients, their first option.<sup id="cite_ref-Housman_Jorizzo_McCarty_Grummer_2003_p._50_13-0" class="reference"><a href="#cite_note-Housman_Jorizzo_McCarty_Grummer_2003_p._50-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Diltiazem" title="Diltiazem">Diltiazem</a> in combination can be beneficial for patients with calcified <a href="/wiki/Nodule_(medicine)" title="Nodule (medicine)">nodules</a>.<sup id="cite_ref-Morgan_Callen_2001_pp._2129–2132_14-0" class="reference"><a href="#cite_note-Morgan_Callen_2001_pp._2129–2132-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Topical_corticosteroids" class="mw-redirect" title="Topical corticosteroids">Topical corticosteroids</a>, primarily <a href="/wiki/Clobetasol_propionate" title="Clobetasol propionate">clobetasol propionate</a>, may be added occasionally.<sup id="cite_ref-Yell_Burge_1993_pp._103–103_15-0" class="reference"><a href="#cite_note-Yell_Burge_1993_pp._103–103-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> </p><p><a href="/wiki/Thalidomide" title="Thalidomide">Thalidomide</a> is regarded as the most effective treatment for lupus erythematosus panniculitis.<sup id="cite_ref-Housman_Jorizzo_McCarty_Grummer_2003_p._50_13-1" class="reference"><a href="#cite_note-Housman_Jorizzo_McCarty_Grummer_2003_p._50-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-BURROWS_WALPORT_HAMMOND_DAVEY_1991_pp._62–67_16-0" class="reference"><a href="#cite_note-BURROWS_WALPORT_HAMMOND_DAVEY_1991_pp._62–67-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Epidemiology">Epidemiology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=6" title="Edit section: Epidemiology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Lupus erythematosus panniculitis may impact both sexes, but women are more likely to experience it. The percentages of frequency in case series vary, with different reports&#160;having female-to-male&#160;ratios of 2:1, 3:1, 4:1, and 9:1.<sup id="cite_ref-spectrum_of_subcuticular_T‐cell_17-0" class="reference"><a href="#cite_note-spectrum_of_subcuticular_T‐cell-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Fraga_2008_3-3" class="reference"><a href="#cite_note-Fraga_2008-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p><p>Although the age at which the disease manifests itself varies as well, most patients are between 30 and 60 years old.<sup id="cite_ref-Fraga_2008_3-4" class="reference"><a href="#cite_note-Fraga_2008-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> The median age was 41 years old in a set of 40 cases,<sup id="cite_ref-a_case_series_6-3" class="reference"><a href="#cite_note-a_case_series-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup> and 42 years old in another Spanish series.<sup id="cite_ref-Fraga_2008_3-5" class="reference"><a href="#cite_note-Fraga_2008-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> Asian patients appear to be affected by lupus erythematosus panniculitis at a slightly younger age group, with a mean age of 31.<sup id="cite_ref-cutaneous_marker_18-0" class="reference"><a href="#cite_note-cutaneous_marker-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-clinicopathologic_study_19-0" class="reference"><a href="#cite_note-clinicopathologic_study-19"><span class="cite-bracket">&#91;</span>19<span class="cite-bracket">&#93;</span></a></sup> Cases involving children are uncommon.<sup id="cite_ref-Lupus_Profundus_in_Childhood_20-0" class="reference"><a href="#cite_note-Lupus_Profundus_in_Childhood-20"><span class="cite-bracket">&#91;</span>20<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-unusual_manifestations_21-0" class="reference"><a href="#cite_note-unusual_manifestations-21"><span class="cite-bracket">&#91;</span>21<span class="cite-bracket">&#93;</span></a></sup> Rarely, <a href="/wiki/Neonatal_lupus_erythematosus" title="Neonatal lupus erythematosus">neonatal lupus</a> has been linked to lupus erythematosus panniculitis.<sup id="cite_ref-neonatal_lupus_22-0" class="reference"><a href="#cite_note-neonatal_lupus-22"><span class="cite-bracket">&#91;</span>22<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=7" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Lupus_erythematosus" title="Lupus erythematosus">Lupus erythematosus</a></li> <li><a href="/wiki/List_of_cutaneous_conditions" class="mw-redirect" title="List of cutaneous conditions">List of cutaneous conditions</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=8" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-Andrews-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-Andrews_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Andrews_1-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"> <style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFWilliam_D._JamesTimothy_G._BergerDirk_M._Elston2015" class="citation book cs1">William D. James; Timothy G. Berger; Dirk M. Elston (2015). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=Np6cCQAAQBAJ&amp;pg=PA156"><i>Andrews' Diseases of the Skin: Clinical Dermatology</i></a> (12th&#160;ed.). <a href="/wiki/Elsevier" title="Elsevier">Elsevier</a>. p.&#160;156. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-0-323-31967-6" title="Special:BookSources/978-0-323-31967-6"><bdi>978-0-323-31967-6</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Andrews%27+Diseases+of+the+Skin%3A+Clinical+Dermatology&amp;rft.pages=156&amp;rft.edition=12th&amp;rft.pub=Elsevier&amp;rft.date=2015&amp;rft.isbn=978-0-323-31967-6&amp;rft.au=William+D.+James&amp;rft.au=Timothy+G.+Berger&amp;rft.au=Dirk+M.+Elston&amp;rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DNp6cCQAAQBAJ%26pg%3DPA156&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ALupus+erythematosus+panniculitis" class="Z3988"></span></span> </li> <li id="cite_note-Bolognia-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-Bolognia_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Bolognia_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Bolognia_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRapini,_Ronald_P.Bolognia,_Jean_L.Jorizzo,_Joseph_L.2007" class="citation book cs1">Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). <i>Dermatology: 2-Volume Set</i>. St. Louis: Mosby. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a>&#160;<a href="/wiki/Special:BookSources/978-1-4160-2999-1" title="Special:BookSources/978-1-4160-2999-1"><bdi>978-1-4160-2999-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Dermatology%3A+2-Volume+Set&amp;rft.place=St.+Louis&amp;rft.pub=Mosby&amp;rft.date=2007&amp;rft.isbn=978-1-4160-2999-1&amp;rft.au=Rapini%2C+Ronald+P.&amp;rft.au=Bolognia%2C+Jean+L.&amp;rft.au=Jorizzo%2C+Joseph+L.&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ALupus+erythematosus+panniculitis" class="Z3988"></span></span> </li> <li id="cite_note-Fraga_2008-3"><span class="mw-cite-backlink">^ <a href="#cite_ref-Fraga_2008_3-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Fraga_2008_3-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Fraga_2008_3-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-Fraga_2008_3-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-Fraga_2008_3-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-Fraga_2008_3-5"><sup><i><b>f</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFragaGarcía-Díez2008" class="citation journal cs1">Fraga, Javier; García-Díez, Amaro (2008). "Lupus Erythematosus Panniculitis". <i>Dermatologic Clinics</i>. <b>26</b> (4). Elsevier BV: 453–463. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.det.2008.06.002">10.1016/j.det.2008.06.002</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0733-8635">0733-8635</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18793977">18793977</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Dermatologic+Clinics&amp;rft.atitle=Lupus+Erythematosus+Panniculitis&amp;rft.volume=26&amp;rft.issue=4&amp;rft.pages=453-463&amp;rft.date=2008&amp;rft.issn=0733-8635&amp;rft_id=info%3Apmid%2F18793977&amp;rft_id=info%3Adoi%2F10.1016%2Fj.det.2008.06.002&amp;rft.aulast=Fraga&amp;rft.aufirst=Javier&amp;rft.au=Garc%C3%ADa-D%C3%ADez%2C+Amaro&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ALupus+erythematosus+panniculitis" class="Z3988"></span></span> </li> <li id="cite_note-deficiency_of_C4-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-deficiency_of_C4_4-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNousariKimyai-AsadiProvost1999" class="citation journal cs1">Nousari, Hossein C.; Kimyai-Asadi, Arash; Provost, Thomas T. (1999). "Generalized lupus erythematosus profundus in a patient with genetic partial deficiency of C4". <i>Journal of the American Academy of Dermatology</i>. <b>41</b> (2). Elsevier BV: 362–364. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fs0190-9622%2899%2970389-0">10.1016/s0190-9622(99)70389-0</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0190-9622">0190-9622</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10426934">10426934</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Journal+of+the+American+Academy+of+Dermatology&amp;rft.atitle=Generalized+lupus+erythematosus+profundus+in+a+patient+with+genetic+partial+deficiency+of+C4&amp;rft.volume=41&amp;rft.issue=2&amp;rft.pages=362-364&amp;rft.date=1999&amp;rft.issn=0190-9622&amp;rft_id=info%3Apmid%2F10426934&amp;rft_id=info%3Adoi%2F10.1016%2Fs0190-9622%2899%2970389-0&amp;rft.aulast=Nousari&amp;rft.aufirst=Hossein+C.&amp;rft.au=Kimyai-Asadi%2C+Arash&amp;rft.au=Provost%2C+Thomas+T.&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ALupus+erythematosus+panniculitis" class="Z3988"></span></span> </li> <li id="cite_note-Cribier_2005_pp._243–248-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-Cribier_2005_pp._243–248_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFCribier2005" class="citation journal cs1 cs1-prop-foreign-lang-source">Cribier, Bernard (2005). 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SAGE Publications: 403–405. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1191%2F0961203305lu2088cr">10.1191/0961203305lu2088cr</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0961-2033">0961-2033</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15934442">15934442</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a>&#160;<a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:8871456">8871456</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Lupus&amp;rft.atitle=A+case+of+lupus+erythematosus+profundus+with+unusual+manifestations&amp;rft.volume=14&amp;rft.issue=5&amp;rft.pages=403-405&amp;rft.date=2005&amp;rft.issn=0961-2033&amp;rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A8871456%23id-name%3DS2CID&amp;rft_id=info%3Apmid%2F15934442&amp;rft_id=info%3Adoi%2F10.1191%2F0961203305lu2088cr&amp;rft.aulast=Bacanli&amp;rft.aufirst=A&amp;rft.au=Uzun%2C+S&amp;rft.au=Ciftcioglu%2C+M+A&amp;rft.au=Alpsoy%2C+E&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ALupus+erythematosus+panniculitis" class="Z3988"></span></span> </li> <li id="cite_note-neonatal_lupus-22"><span class="mw-cite-backlink"><b><a href="#cite_ref-neonatal_lupus_22-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNitta1997" class="citation journal cs1">Nitta, Y. (1997). "Lupus erythematosus profundus associated with neonatal lupus erythematosus". <i>British Journal of Dermatology</i>. <b>136</b> (1): 112–114. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1046%2Fj.1365-2133.1997.d01-1154.x">10.1046/j.1365-2133.1997.d01-1154.x</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9039307">9039307</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a>&#160;<a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:2491393">2491393</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=British+Journal+of+Dermatology&amp;rft.atitle=Lupus+erythematosus+profundus+associated+with+neonatal+lupus+erythematosus&amp;rft.volume=136&amp;rft.issue=1&amp;rft.pages=112-114&amp;rft.date=1997&amp;rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A2491393%23id-name%3DS2CID&amp;rft_id=info%3Apmid%2F9039307&amp;rft_id=info%3Adoi%2F10.1046%2Fj.1365-2133.1997.d01-1154.x&amp;rft.aulast=Nitta&amp;rft.aufirst=Y.&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ALupus+erythematosus+panniculitis" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=9" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation journal cs1">Patel, RakshaM; Marfatia, YS (2010). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856385">"Lupus panniculitis as an initial manifestation of systemic lupus erythematosus"</a>. <i>Indian Journal of Dermatology</i>. <b>55</b> (1). Medknow: 99. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.4103%2F0019-5154.60364">10.4103/0019-5154.60364</a></span>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0019-5154">0019-5154</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a>&#160;<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856385">2856385</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20418989">20418989</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Indian+Journal+of+Dermatology&amp;rft.atitle=Lupus+panniculitis+as+an+initial+manifestation+of+systemic+lupus+erythematosus&amp;rft.volume=55&amp;rft.issue=1&amp;rft.pages=99&amp;rft.date=2010&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2856385%23id-name%3DPMC&amp;rft.issn=0019-5154&amp;rft_id=info%3Apmid%2F20418989&amp;rft_id=info%3Adoi%2F10.4103%2F0019-5154.60364&amp;rft.aulast=Patel&amp;rft.aufirst=RakshaM&amp;rft.au=Marfatia%2C+YS&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2856385&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ALupus+erythematosus+panniculitis" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation journal cs1">Sari, Agnes Rosarina Prita; Ferronika, Paranita; Soebono, Hardyanto; Yogianti, Flandiana (July 6, 2022). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099288">"Lupus Panniculitis: a rare bilateral and symmetrical manifestation of cutaneous Lupus Erythematosus in an adolescent girl"</a>. <i>Dermatology Reports</i>. <b>15</b> (1). PAGEPress Publications: 9515. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.4081%2Fdr.2022.9515">10.4081/dr.2022.9515</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a>&#160;<a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/2036-7406">2036-7406</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a>&#160;<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099288">10099288</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a>&#160;<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/37063393">37063393</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.jtitle=Dermatology+Reports&amp;rft.atitle=Lupus+Panniculitis%3A+a+rare+bilateral+and+symmetrical+manifestation+of+cutaneous+Lupus+Erythematosus+in+an+adolescent+girl&amp;rft.volume=15&amp;rft.issue=1&amp;rft.pages=9515&amp;rft.date=2022-07-06&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10099288%23id-name%3DPMC&amp;rft.issn=2036-7406&amp;rft_id=info%3Apmid%2F37063393&amp;rft_id=info%3Adoi%2F10.4081%2Fdr.2022.9515&amp;rft.aulast=Sari&amp;rft.aufirst=Agnes+Rosarina+Prita&amp;rft.au=Ferronika%2C+Paranita&amp;rft.au=Soebono%2C+Hardyanto&amp;rft.au=Yogianti%2C+Flandiana&amp;rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC10099288&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ALupus+erythematosus+panniculitis" class="Z3988"></span></li></ul> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lupus_erythematosus_panniculitis&amp;action=edit&amp;section=10" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://www.pathologyoutlines.com/topic/skinnontumorlupuspanniculitis.html">Pathology Outlines</a></li> <li><a rel="nofollow" class="external text" href="https://www.visualdx.com/visualdx/diagnosis/lupus+panniculitis?diagnosisId=51888&amp;moduleId=101">VisualDx</a></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output 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ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist dd dd:first-child::before,.mw-parser-output .hlist dd dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:")";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:" "counter(listitem)"\a0 "}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:" ("counter(listitem)"\a0 "}</style><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"></div><div role="navigation" class="navbox" aria-label="Navbox" style="width:100%; margin:0.5em 0 0.5em 0;;padding:3px"><table class="nowraplinks navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background: #EAECF0;color:black;">Classification</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><div style="position:relative; float:right; font-size:0.8em;"><a href="https://www.wikidata.org/wiki/Q6704853" class="extiw" title="d:Q6704853">D</a></div><div class="hlist" style="text-align:left;"><ul><li><b><a href="/wiki/International_Statistical_Classification_of_Diseases_and_Related_Health_Problems" class="mw-redirect" title="International Statistical Classification of Diseases and Related Health Problems">ICD</a>-<a href="/wiki/ICD-11" title="ICD-11">11</a></b>: <a rel="nofollow" class="external text" href="https://icd.who.int/browse/latest-release/mms/en#1849568465%2Fother">EB51.Y</a></li><li><b><a href="/wiki/International_Statistical_Classification_of_Diseases_and_Related_Health_Problems" class="mw-redirect" title="International Statistical Classification of Diseases and Related Health Problems">ICD</a>-<a href="/wiki/ICD-10" title="ICD-10">10</a></b>: <a rel="nofollow" class="external text" href="https://icd.who.int/browse10/2019/en#/L93.2">L93.2</a></li><li><b><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a></b>: <a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D015435">D015435</a></li><li><b><a href="/wiki/SNOMED_CT" title="SNOMED CT">SNOMED CT</a></b>: <a rel="nofollow" class="external text" href="http://snomed.info/id/239888002">239888002</a></li></ul></div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: #EAECF0;color:black;">External resources</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><div class="hlist" style="text-align:left;"><ul><li><b><a href="/wiki/Orphanet" title="Orphanet">Orphanet</a></b>: <a rel="nofollow" class="external text" href="https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&amp;Expert=90285">90285</a></li><li><b>Scholia</b>: <a class="external text" href="https://tools.wmflabs.org/scholia/topic/Q6704853">Q6704853</a></li></ul></div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Disorders_of_subcutaneous_fat" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Disorders_of_subcutaneous_fat" title="Template:Disorders of subcutaneous fat"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Disorders_of_subcutaneous_fat" title="Template talk:Disorders of subcutaneous fat"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Disorders_of_subcutaneous_fat" title="Special:EditPage/Template:Disorders of subcutaneous fat"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Disorders_of_subcutaneous_fat" style="font-size:114%;margin:0 4em">Disorders of <a href="/wiki/Subcutaneous_fat" class="mw-redirect" title="Subcutaneous fat">subcutaneous fat</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Panniculitis" title="Panniculitis">Panniculitis</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Lobular</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>without vasculitis <ul><li><a href="/wiki/Cold_panniculitis" class="mw-redirect" title="Cold panniculitis">Cold</a></li> <li><a href="/wiki/Cytophagic_histiocytic_panniculitis" class="mw-redirect" title="Cytophagic histiocytic panniculitis">Cytophagic histiocytic</a></li> <li><a href="/wiki/Factitial_panniculitis" class="mw-redirect" title="Factitial panniculitis">Factitial</a></li> <li><a href="/wiki/Gouty_panniculitis" class="mw-redirect" title="Gouty panniculitis">Gouty</a></li> <li><a href="/wiki/Pancreatic_panniculitis" class="mw-redirect" title="Pancreatic panniculitis">Pancreatic</a></li> <li><a href="/wiki/Traumatic_panniculitis" class="mw-redirect" title="Traumatic panniculitis">Traumatic</a></li></ul></li></ul> <ul><li><i>needle-shaped clefts</i> <ul><li><a href="/wiki/Subcutaneous_fat_necrosis_of_the_newborn" title="Subcutaneous fat necrosis of the newborn">Subcutaneous fat necrosis of the newborn</a></li> <li><a href="/wiki/Sclerema_neonatorum" title="Sclerema neonatorum">Sclerema neonatorum</a></li> <li><a href="/wiki/Post-steroid_panniculitis" class="mw-redirect" title="Post-steroid panniculitis">Post-steroid panniculitis</a></li></ul></li> <li><a href="/wiki/Lipodermatosclerosis" title="Lipodermatosclerosis">Lipodermatosclerosis</a></li> <li><a href="/wiki/Weber%E2%80%93Christian_disease" title="Weber–Christian disease">Weber–Christian disease</a></li> <li><a class="mw-selflink selflink">Lupus erythematosus panniculitis</a></li> <li><a href="/wiki/Sclerosing_lipogranuloma" class="mw-redirect" title="Sclerosing lipogranuloma">Sclerosing lipogranuloma</a></li></ul> <ul><li><i>with vasculitis:</i> <a href="/wiki/Nodular_vasculitis" class="mw-redirect" title="Nodular vasculitis">Nodular vasculitis</a>/<a href="/wiki/Erythema_induratum" title="Erythema induratum">Erythema induratum</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Septal_panniculitis" title="Septal panniculitis">Septal</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>without vasculitis:</i> <a href="/wiki/Alpha-1_antitrypsin_deficiency_panniculitis" class="mw-redirect" title="Alpha-1 antitrypsin deficiency panniculitis">Alpha-1 antitrypsin deficiency panniculitis</a></li> <li><a href="/wiki/Erythema_nodosum" title="Erythema nodosum">Erythema nodosum</a> <ul><li><a href="/wiki/Acute_erythema_nodosum" class="mw-redirect" title="Acute erythema nodosum">Acute</a></li> <li><a href="/wiki/Chronic_erythema_nodosum" class="mw-redirect" title="Chronic erythema nodosum">Chronic</a></li></ul></li></ul> <ul><li><i>with vasculitis:</i> <a href="/wiki/Superficial_thrombophlebitis" title="Superficial thrombophlebitis">Superficial thrombophlebitis</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Lipodystrophy" title="Lipodystrophy">Lipodystrophy</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Acquired</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>generalized:</i> <a href="/wiki/Acquired_generalized_lipodystrophy" title="Acquired generalized lipodystrophy">Acquired generalized lipodystrophy</a></li></ul> <ul><li><i>partial:</i> <a href="/wiki/Barraquer%E2%80%93Simons_syndrome" title="Barraquer–Simons syndrome">Acquired partial lipodystrophy</a></li> <li><a href="/wiki/Centrifugal_lipodystrophy" title="Centrifugal lipodystrophy">Centrifugal lipodystrophy</a></li> <li><a href="/wiki/HIV-associated_lipodystrophy" title="HIV-associated lipodystrophy">HIV-associated lipodystrophy</a></li> <li><a href="/wiki/Lipoatrophia_annularis" title="Lipoatrophia annularis">Lipoatrophia annularis</a></li></ul> <ul><li><i>localized:</i> <a href="/wiki/Localized_lipodystrophy" title="Localized lipodystrophy">Localized lipodystrophy</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Congenital</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Congenital_generalized_lipodystrophy" title="Congenital generalized lipodystrophy">Congenital generalized lipodystrophy</a></li> <li><a href="/wiki/Familial_partial_lipodystrophy" title="Familial partial lipodystrophy">Familial partial lipodystrophy</a></li> <li><a href="/wiki/Marfanoid%E2%80%93progeroid%E2%80%93lipodystrophy_syndrome" title="Marfanoid–progeroid–lipodystrophy syndrome">Marfanoid–progeroid–lipodystrophy syndrome</a></li> <li><a href="/wiki/Poland_syndrome" title="Poland syndrome">Poland syndrome</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <!-- NewPP limit report Parsed by mw‐web.codfw.main‐f69cdc8f6‐9nxpb Cached time: 20241122145147 Cache expiry: 2592000 Reduced expiry: false Complications: [vary‐revision‐sha1, show‐toc] CPU time usage: 0.660 seconds Real time usage: 0.811 seconds Preprocessor visited node count: 2485/1000000 Post‐expand include size: 87280/2097152 bytes Template argument size: 1358/2097152 bytes Highest expansion depth: 12/100 Expensive parser function count: 3/500 Unstrip recursion depth: 1/20 Unstrip post‐expand size: 112643/5000000 bytes Lua time usage: 0.455/10.000 seconds Lua memory usage: 17697552/52428800 bytes Number of Wikibase entities loaded: 1/400 --> <!-- Transclusion expansion time report (%,ms,calls,template) 100.00% 748.379 1 -total 36.97% 276.704 1 Template:Reflist 29.15% 218.125 4 Template:Navbox 25.49% 190.784 1 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