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elementor-element-f641055" data-id="f641055" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-a4342f3 elementor-view-stacked elementor-position-right elementor-vertical-align-middle elementor-mobile-position-left elementor-shape-circle elementor-widget elementor-widget-icon-box" data-id="a4342f3" data-element_type="widget" data-widget_type="icon-box.default"> <div class="elementor-widget-container"> <div class="elementor-icon-box-wrapper"> <div class="elementor-icon-box-icon"> <span class="elementor-icon elementor-animation-"> <i aria-hidden="true" class="far fa-calendar-alt"></i> </span> </div> <div class="elementor-icon-box-content"> <h4 class="elementor-icon-box-title"> <span > Date </span> </h4> <p class="elementor-icon-box-description"> November 18-20, 2024 </p> </div> </div> </div> </div> </div> </div> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element 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elementor-element-a6f9e49 elementor-align-center elementor-mobile-align-left elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-invisible elementor-widget elementor-widget-icon-list" data-id="a6f9e49" data-element_type="widget" data-settings="{"_animation":"fadeInUp","_animation_delay":1000}" data-widget_type="icon-list.default"> <div class="elementor-widget-container"> <ul class="elementor-icon-list-items"> <li class="elementor-icon-list-item"> <span class="elementor-icon-list-icon"> <i aria-hidden="true" class="far fa-arrow-alt-circle-right"></i> </span> <span class="elementor-icon-list-text">Abstract Submission Opens: February 20, 2024</span> </li> <li class="elementor-icon-list-item"> <span class="elementor-icon-list-icon"> <i aria-hidden="true" class="far fa-arrow-alt-circle-right"></i> </span> <span class="elementor-icon-list-text"> Early Bird Registration Start: March 01, 2024</span> </li> </ul> </div> </div> <div class="elementor-element elementor-element-1dd4bae elementor-align-center elementor-invisible elementor-widget elementor-widget-button" data-id="1dd4bae" data-element_type="widget" data-settings="{"_animation":"fadeInUp","_animation_delay":1500}" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://cognitionconferences.com/cellscience/registration/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-long-arrow-alt-right"></i> </span> <span class="elementor-button-text">Register Now</span> </span> </a> </div> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-top-section elementor-element elementor-element-0fc8139 home-sec elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="0fc8139" data-element_type="section" data-settings="{"background_background":"classic"}"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-22f51fc" data-id="22f51fc" data-element_type="column" data-settings="{"background_background":"classic"}"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-background-overlay"></div> <div class="elementor-element elementor-element-2452581 elementor-widget elementor-widget-heading" data-id="2452581" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">Conference Start In... </h2> </div> </div> <div class="elementor-element elementor-element-c83f849 elementor-widget__width-initial elementor-widget elementor-widget-heading" data-id="c83f849" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h4 class="elementor-heading-title elementor-size-default">Best networking and one-to-one meeting opportunity </h4> </div> </div> <div class="elementor-element elementor-element-31d3da1 elementor-widget elementor-widget-shortcode" data-id="31d3da1" data-element_type="widget" data-widget_type="shortcode.default"> <div class="elementor-widget-container"> <div class="elementor-shortcode"><script> $(document).ready(function() { function updateCountdown() { // Set the target date to December 31, 2023, at midnight in the Asia/Kolkata timezone (IST) // Get the target date from PHP const targetDate = new Date(1731868200000); // Get the current date and time in the Asia/Kolkata timezone (IST) const currentDate = new Date(); // Calculate the time difference in milliseconds const timeDifference = targetDate - currentDate; if (timeDifference <= 0) { // The countdown has ended $('#days').html('0 days'); $('#hours').html('0 hours'); $('#minutes').html('0 minutes'); $('#seconds').html('0 seconds'); } else { // Calculate days, hours, minutes, and seconds const days = Math.floor(timeDifference / (1000 * 60 * 60 * 24)); const hours = Math.floor((timeDifference % (1000 * 60 * 60 * 24)) / (1000 * 60 * 60)); const minutes = Math.floor((timeDifference % (1000 * 60 * 60)) / (1000 * 60)); const seconds = Math.floor((timeDifference % (1000 * 60)) / 1000); // Display the countdown in separate div elements $('#edays').html(days + ' days'); $('#hours').html(hours + ' hours'); $('#minutes').html(minutes + ' minutes'); $('#seconds').html(seconds + ' seconds'); } } // Update the countdown every second setInterval(updateCountdown, 1000); }); </script> <div class="customcounter"> <div id="edays">0 days</div> <div id="hours">0 hours</div> <div id="minutes">0 minutes</div> <div id="seconds">0 seconds</div> </div> </div> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-top-section elementor-element elementor-element-85c2d62 home-sec elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="85c2d62" data-element_type="section"> <div class="elementor-container elementor-column-gap-custom"> <div class="elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-748a794" data-id="748a794" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <section class="elementor-section elementor-inner-section elementor-element elementor-element-85eba35 columnbox elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="85eba35" data-element_type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-b740dd3" data-id="b740dd3" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-271e98c elementor-widget elementor-widget-heading" data-id="271e98c" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h3 class="elementor-heading-title elementor-size-default">Conference Details</h3> </div> </div> <div class="elementor-element elementor-element-a80e238 elementor-view-stacked elementor-position-left elementor-vertical-align-middle elementor-mobile-position-left elementor-shape-circle elementor-widget elementor-widget-icon-box" data-id="a80e238" data-element_type="widget" data-widget_type="icon-box.default"> <div class="elementor-widget-container"> <div class="elementor-icon-box-wrapper"> <div class="elementor-icon-box-icon"> <span class="elementor-icon elementor-animation-"> <i aria-hidden="true" class="far fa-calendar-alt"></i> </span> </div> <div class="elementor-icon-box-content"> <h4 class="elementor-icon-box-title"> <span > Date </span> </h4> <p class="elementor-icon-box-description"> November 18-20, 2024 </p> </div> </div> </div> </div> <div class="elementor-element elementor-element-96ec8bc elementor-view-stacked elementor-position-left elementor-vertical-align-middle elementor-mobile-position-left elementor-shape-circle elementor-widget elementor-widget-icon-box" data-id="96ec8bc" data-element_type="widget" data-widget_type="icon-box.default"> <div class="elementor-widget-container"> <div class="elementor-icon-box-wrapper"> <div class="elementor-icon-box-icon"> <span class="elementor-icon elementor-animation-"> <i aria-hidden="true" class="fas fa-map-marker-alt"></i> </span> </div> <div class="elementor-icon-box-content"> <h4 class="elementor-icon-box-title"> <span > Venue </span> </h4> <p class="elementor-icon-box-description"> Rome, Italy </p> </div> </div> </div> </div> </div> </div> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c2d5cba" data-id="c2d5cba" data-element_type="column" data-settings="{"background_background":"classic","animation":"none"}"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-5d324de elementor-position-top elementor-widget elementor-widget-image-box" data-id="5d324de" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><img fetchpriority="high" decoding="async" width="500" height="500" src="https://cognitionconferences.com/cellscience/wp-content/uploads/2023/09/download-broucher.png" class="elementor-animation-grow attachment-full size-full wp-image-5474" alt="" /></figure><div class="elementor-image-box-content"><h4 class="elementor-image-box-title">Download Brochure</h4></div></div> </div> </div> <div class="elementor-element elementor-element-929ab39 elementor-align-center elementor-widget elementor-widget-button" data-id="929ab39" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://cognitionconferences.com/cellscience/brochure-form/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">Download Brochure</span> </span> </a> </div> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-inner-section elementor-element elementor-element-02d3672 columnbox samllgap elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="02d3672" data-element_type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c3e97df" data-id="c3e97df" data-element_type="column" data-settings="{"background_background":"classic","animation":"none","animation_delay":1000}"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-b49432d elementor-position-top elementor-widget elementor-widget-image-box" data-id="b49432d" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><img decoding="async" width="500" height="500" src="https://cognitionconferences.com/cellscience/wp-content/uploads/2023/09/temtative-programe.png" class="elementor-animation-grow attachment-full size-full wp-image-5476" alt="" /></figure><div class="elementor-image-box-content"><h4 class="elementor-image-box-title">Final Program</h4></div></div> </div> </div> <div class="elementor-element elementor-element-f1fe5c7 elementor-align-center elementor-widget elementor-widget-button" data-id="f1fe5c7" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://cognitionconferences.com/cellscience/tentative-program/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">Download Here</span> </span> </a> </div> </div> </div> </div> </div> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-e16902b" data-id="e16902b" data-element_type="column" data-settings="{"background_background":"classic","animation":"none","animation_delay":500}"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-5d0df97 elementor-position-top elementor-widget elementor-widget-image-box" data-id="5d0df97" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><img decoding="async" width="500" height="500" src="https://cognitionconferences.com/cellscience/wp-content/uploads/2023/11/speaker-guidelines-img.webp" class="elementor-animation-grow attachment-full size-full wp-image-6796" alt="" srcset="https://cognitionconferences.com/cellscience/wp-content/uploads/2023/11/speaker-guidelines-img.webp 500w, https://cognitionconferences.com/cellscience/wp-content/uploads/2023/11/speaker-guidelines-img-300x300.webp 300w, https://cognitionconferences.com/cellscience/wp-content/uploads/2023/11/speaker-guidelines-img-150x150.webp 150w" sizes="(max-width: 500px) 100vw, 500px" /></figure><div class="elementor-image-box-content"><h4 class="elementor-image-box-title">Speaker Guidelines</h4></div></div> </div> </div> <div class="elementor-element elementor-element-d75f5da elementor-align-center elementor-widget elementor-widget-button" data-id="d75f5da" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://cognitionconferences.com/cellscience/speaker-guidelines/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">Download Now</span> </span> </a> </div> </div> </div> </div> </div> </div> </section> </div> </div> <div class="elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-ea2816f" data-id="ea2816f" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-8b61f82 elementor-widget elementor-widget-heading" data-id="8b61f82" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h3 class="elementor-heading-title elementor-size-default">About </h3> </div> </div> <div class="elementor-element elementor-element-8eaf3ab elementor-widget elementor-widget-heading" data-id="8eaf3ab" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">Cell Science Conference</h2> </div> </div> <div class="elementor-element elementor-element-31d4b60 elementor-widget elementor-widget-text-editor" data-id="31d4b60" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <p>You’re cordially invited to join us at the upcoming <a href="https://cognitionconferences.com/cellscience/">International Conference on Cell Science & Molecular Biology</a>, hosted by <a href="https://cognitionconferences.com/conferences/">Cognition Conferences</a> in the enchanting city of Rome, Italy, from November 18th to 20th, 2024. Under the theme, “<a href="https://cognitionconferences.com/cellscience/scientific-sessions/">Cellular Insights: Unraveling the Mechanisms of Life</a>,” this event promises a deep dive into the fascinating world of cellular exploration. Prepare to be captivated by a lineup of engaging activities, including keynote presentations by esteemed experts, interactive oral sessions, illuminating plenary talks, invigorating young research forums, visually compelling poster presentations, collaborative student forums, hands-on technical workshops, insightful symposia, and exciting start-up opportunities.</p><p><a href="https://cognitionconferences.com/">Cognition Conferences serves</a> as more than just a gathering—it’s a dynamic platform where researchers converge to share their insights, unveil groundbreaking outcomes, and chart strategic roadmaps. By fostering collaboration and nurturing a sense of shared responsibility, we aim to catalyze positive change and contribute to building a brighter world together.</p> </div> </div> <div class="elementor-element elementor-element-b9d0129 darkbtn elementor-widget elementor-widget-button" data-id="b9d0129" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://cognitionconferences.com/cellscience/about-us/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-long-arrow-alt-right"></i> </span> <span class="elementor-button-text">More About Conference</span> </span> </a> </div> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-top-section elementor-element elementor-element-c51b0aa elementor-section-content-middle home-session home-sec elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="c51b0aa" data-element_type="section" data-settings="{"background_background":"classic","animation":"none"}"> <div class="elementor-background-overlay"></div> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e516cdc" data-id="e516cdc" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-1874833 elementor-widget elementor-widget-heading" data-id="1874833" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">Scientific Session</h2> </div> </div> <section class="elementor-section elementor-inner-section elementor-element elementor-element-56f7e91 elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="56f7e91" data-element_type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-5097225" data-id="5097225" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-9b210d1 elementor-widget__width-initial elementor-widget elementor-widget-heading" data-id="9b210d1" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h4 class="elementor-heading-title elementor-size-default">Below are the scientific sessions of the conference</h4> </div> </div> </div> </div> </div> </section> <div class="elementor-element elementor-element-4c547c6 elementor-widget elementor-widget-shortcode" data-id="4c547c6" data-element_type="widget" data-widget_type="shortcode.default"> <div class="elementor-widget-container"> <div class="elementor-shortcode"> <div class="container"> <div class="row"> <ul class="session-lists"> <li><span>Session 1</span> Stem Cells: Regenerative Potential</li> <li><span>Session 2</span> Chromatin Dynamics: Epigenetic Regulation</li> <li><span>Session 3</span> Signaling Pathways: Cellular Communication</li> <li><span>Session 4</span> Single-Cell Analysis: Diversity Profiling</li> <li><span>Session 5</span> Cancer Biology: Therapeutic Targets</li> <li><span>Session 6</span> Aging Mechanisms: Cellular Senescence</li> <li><span>Session 7</span> Neurobiology: Brain Disorder Insights</li> <li><span>Session 8</span> RNA Regulation: Gene Expression</li> <li><span>Session 9</span> Mitochondrial Biology: Energy Production</li> <li><span>Session 10</span> Genome Editing: Precision Engineering</li> <li><span>Session 11</span> Cell Cycle: Regulation Mechanisms</li> <li><span>Session 12</span> Immunology: Host Defense Understanding</li> </ul> </div> </div> </div> </div> </div> <section class="elementor-section elementor-inner-section elementor-element elementor-element-69aeedc elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="69aeedc" data-element_type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-9783c9e" data-id="9783c9e" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-8e694e1 elementor-align-right elementor-mobile-align-center elementor-widget elementor-widget-button" data-id="8e694e1" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://cognitionconferences.com/cellscience/abstract-submission/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-long-arrow-alt-right"></i> </span> <span class="elementor-button-text">Submit Abstract</span> </span> </a> </div> </div> </div> </div> </div> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-9265bad" data-id="9265bad" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-e7c4b46 elementor-align-left elementor-mobile-align-center darkbtn elementor-widget elementor-widget-button" data-id="e7c4b46" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://cognitionconferences.com/cellscience/registration/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-long-arrow-alt-right"></i> </span> <span class="elementor-button-text">Register Now</span> </span> </a> </div> </div> </div> </div> </div> </div> </section> </div> </div> </div> </section> <section class="elementor-section elementor-top-section elementor-element elementor-element-cd94c89 regcate home-sec elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="cd94c89" data-element_type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ee82a30" data-id="ee82a30" data-element_type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-722b687 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-heading" data-id="722b687" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">Speakers</h2> </div> </div> <div class="elementor-element elementor-element-151b87b elementor-widget elementor-widget-heading" data-id="151b87b" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h4 class="elementor-heading-title elementor-size-default">There have been many eminent speakers and researchers in the field of cell science who have made significant contributions to our understanding of molecular biology and their impact on various aspects of life. Here are some well-known figures in the field..</h4> </div> </div> <div class="elementor-element elementor-element-652f37f elementor-widget elementor-widget-shortcode" data-id="652f37f" data-element_type="widget" data-widget_type="shortcode.default"> <div class="elementor-widget-container"> <div class="elementor-shortcode"> <div class="speakerbox"> <div class="speakerboxes"> <div class="image-container" style="background: url('https://cognitionconferences.com/cellscience/wp-content/uploads/2024/10/Joseph-J.Tartaglia.png');"> </div> <div class="speakerbox-text"> <p class="c-title"><span>Name:</span> Joseph J.Tartaglia</p> <p class="c-coun"><span>Country:</span> United States </p> <p class="desp">Abstract: Adult stem cell therapy via intramyocardial injection of autologous CD34+ stem cells has been…</p> <div class="profilebtn"> <i class="fa-solid fa-arrow-right-long"></i> <a id="#member7263" href="#" data-bs-toggle="modal" data-bs-target="#member7263">View Profile</a> </div> </div> </div> <div class="modal fade" id="member7263"> <div class="modal-dialog"> <div class="modal-content">  <div class="modal-header"> <div class="mem-img" style="background: url('https://cognitionconferences.com/cellscience/wp-content/uploads/2024/10/Joseph-J.Tartaglia.png');"> </div> <div class="modal-title"> <p class="member-title"><span class="member-name">Name </span> : Joseph J.Tartaglia</p> <p class="member-university"><span class="member-uni">University </span> : </p> <p class="member-country"><span class="modal-title-heading">Country </span> : United States </p> </div> <button type="button" class="btn-close" data-bs-dismiss="modal"></button> </div> <div class="modal-body"> <p style="text-align: left;"><strong>Abstract:</strong></p> <p>Adult stem cell therapy via intramyocardial injection of autologous CD34+ stem cells has been shown to improve exercise capacity and reduce angina frequency and mortality in patients with refractory angina (RA). However, the cost of such therapy is a limitation to its adoption in clinical practice. Our goal was to determine whether the less costly, less invasive, and widely accessible, FDA-approved alternative treatment for RA patients, known as enhanced external counter pulsation (EECP), mobilizes endogenous CD34+ stem cells and whether such mobilization is associated with the clinical benefits seen with intramyocardial injections. We monitored changes in circulating levels of CD34+/CD133+ and CD34+/KDR+ cells in RA patients undergoing EECP therapy and in a comparator cohort of RA patients undergoing an exercise regimen known as cardiac rehabilitation. Changes in exercise capacity in both cohorts were monitored by measuring treadmill times (TT), double product (DP) scores, and Canadian Cardiovascular Society (CCS) angina scores between pre- and post-treatment treadmill stress tests. Circulating levels of CD34+/CD133+ cells increased in patients undergoing EECP and were significant (β = −2.38, <em>p</em> = 0.012) predictors of improved exercise capacity in these patients. CD34+/CD133+ cells isolated from RA patients could differentiate into endothelial cells, and their numbers increased during EECP therapy. Our results support the hypothesis that mobilized CD34+/CD133+ cells repair vascular damage and increase collateral circulation in RA patients. They further support clinical interventions that can mobilize adult CD34+ stem cells as therapy for patients with RA and other vascular diseases.</p> </div> <div class="modal-footer"> <button type="button" class="btn btn-danger" data-bs-dismiss="modal">Close</button> </div> </div> </div> </div> <div class="speakerboxes"> <div class="image-container" style="background: url('https://cognitionconferences.com/cellscience/wp-content/uploads/2024/05/Copy-of-Copy-of-Untitled-Design-1.png');"> </div> <div class="speakerbox-text"> <p class="c-title"><span>Name:</span> Yongchun Cui</p> <p class="c-coun"><span>Country:</span> China</p> <p class="desp">Abstract Objective: Clinically, there is an urgent need for small-diameter artificial vascular grafts (SDAVGs) meeting…</p> <div class="profilebtn"> <i class="fa-solid fa-arrow-right-long"></i> <a id="#member7195" href="#" data-bs-toggle="modal" data-bs-target="#member7195">View Profile</a> </div> </div> </div> <div class="modal fade" id="member7195"> <div class="modal-dialog"> <div class="modal-content">  <div class="modal-header"> <div class="mem-img" style="background: url('https://cognitionconferences.com/cellscience/wp-content/uploads/2024/05/Copy-of-Copy-of-Untitled-Design-1.png');"> </div> <div class="modal-title"> <p class="member-title"><span class="member-name">Name </span> : Yongchun Cui</p> <p class="member-university"><span class="member-uni">University </span> : </p> <p class="member-country"><span class="modal-title-heading">Country </span> : China</p> </div> <button type="button" class="btn-close" data-bs-dismiss="modal"></button> </div> <div class="modal-body"> <p><strong>Abstract</strong></p> <p style="text-align: left;"><strong>Objective: </strong>Clinically, there is an urgent need for small-diameter artificial vascular grafts (SDAVGs) meeting the requirements of rapid endothelialization and thrombotic resistance, and poor vascular remodeling is one of the bottlenecks affecting the clinical transformation of SDAVGs. This study aims to design and fabricate a three-layer biomimetic SDAVG,and utilize single cell RNA-sequencing to explore the mechanism of the vascular remodeling after SDAVG implantation.</p> <p style="text-align: left;"><strong>Methods: </strong>To ensure the safety of the novel three-layer biomimetic SDAVGs in vivo, we evaluated their biocompatibility and hemocompatibility firstly. Then, a porcine carotid artery replacement model was established to analyze the biological performance of the three-layer biomimetic small-diameter artificial vascular graft, and histopathological analysis of tissue sections of vascular grafts was performed by HE and immunohistochemical staining. Additionally, single cell transcriptome sequencing was used to investigate the cell composition and changes after blood vessel implantation.</p> <p style="text-align: left;"><strong>Results: </strong>In all in vitro experiments, the small-diameter artificial blood vessel exhibited excellent biocompatibility and hemocompatibility. Furthermore, in vivo transplantation experiments demonstrated favorable anti-thrombotic properties and minimal intimal hyperplasia. And the small-diameter artificial blood caused no evident inflammatory reaction in tissue in vivo implantation experiments. What’s more, single-cell RNA sequencing revealed that endothelial cells (ECs), vascular smooth cells (SMCs), and myeloid cells were the main cell type in the small-diameter artificial blood, and endothelial-to-mesenchymal transition (EndMT) occurred. RNA velocity showed that ECs subtype transitions from quiescent to proliferating phenotype</p> <p style="text-align: left;"><strong>Conclusion: </strong>The biomimetic small-diameter artificial blood vessel has potential clinical application prospects, and the results of single-cell RNA sequencing provide support for its optimization and clinical translation.</p> </div> <div class="modal-footer"> <button type="button" class="btn btn-danger" data-bs-dismiss="modal">Close</button> </div> </div> </div> </div> <div class="speakerboxes"> <div class="image-container" style="background: url('https://cognitionconferences.com/cellscience/wp-content/uploads/2024/03/Shakhnozakhon-Gaipovaa-1.png');"> </div> <div class="speakerbox-text"> <p class="c-title"><span>Name:</span> Shakhnozakhon Gaipovaa</p> <p class="c-coun"><span>Country:</span> Uzbekistan</p> <p class="desp">Abstract : Today, the recipe for mayonnaise sauces is constantly evolving, considering the high global…</p> <div class="profilebtn"> <i class="fa-solid fa-arrow-right-long"></i> <a id="#member7121" href="#" data-bs-toggle="modal" data-bs-target="#member7121">View Profile</a> </div> </div> </div> <div class="modal fade" id="member7121"> <div class="modal-dialog"> <div class="modal-content">  <div class="modal-header"> <div class="mem-img" style="background: url('https://cognitionconferences.com/cellscience/wp-content/uploads/2024/03/Shakhnozakhon-Gaipovaa-1.png');"> </div> <div class="modal-title"> <p class="member-title"><span class="member-name">Name </span> : Shakhnozakhon Gaipovaa</p> <p class="member-university"><span class="member-uni">University </span> : </p> <p class="member-country"><span class="modal-title-heading">Country </span> : Uzbekistan</p> </div> <button type="button" class="btn-close" data-bs-dismiss="modal"></button> </div> <div class="modal-body"> <p><strong>Abstract :<br /> </strong></p> <p style="text-align: left;">Today, the recipe for mayonnaise sauces is constantly evolving, considering the high global consumption of mayonnaise products and modern concerns about their health value, along with improving the quality of food products. In addition to emulsion products, we can increase the preventive properties of mayonnaise by enriching it with biological substances and functional oils. In the ongoing scientific research, we have studied the proximal analysis and toxicological evaluation of prepared mayonnaise based on new patented biologically active substances, and it has been determined that it has beneficial properties. Based on the latest recipe, the widely-used starch component, was replaced with sesame, and lemon peel was added as a natural antioxidant. Compared to the conventional mayonnaise recipe, fortified mayonnaise has a higher protein and lower fat content, offering a healthier product with functional properties. In addition, fresh mayonnaise has lower peroxide and anisidine values, indicating higher resistance to oxidative damage. Mayonnaise enriched with biologically active raw materials, sesame, and lemon peel proved safe in the conducted studies and met safety requirements regarding toxicological parameters.</p> <p style="text-align: left;"><strong>Keywords:</strong> Mayonnaise; Sesame meal; Lemon zest; Emulsion system</p> </div> <div class="modal-footer"> <button type="button" class="btn btn-danger" data-bs-dismiss="modal">Close</button> </div> </div> </div> </div> <div class="speakerboxes"> <div class="image-container" style="background: url('https://cognitionconferences.com/cellscience/wp-content/uploads/2024/03/Shantha-Selva-Kumari.png');"> </div> <div class="speakerbox-text"> <p class="c-title"><span>Name:</span> Wei Li</p> <p class="c-coun"><span>Country:</span> USA</p> <p class="desp">Abstract: Sperm-associated antigen 6 (SPAG6) is the mammalian orthologue of Chlamydomonas PF16, a protein localizing…</p> <div class="profilebtn"> <i class="fa-solid fa-arrow-right-long"></i> <a id="#member7119" href="#" data-bs-toggle="modal" data-bs-target="#member7119">View Profile</a> </div> </div> </div> <div class="modal fade" id="member7119"> <div class="modal-dialog"> <div class="modal-content">  <div class="modal-header"> <div class="mem-img" style="background: url('https://cognitionconferences.com/cellscience/wp-content/uploads/2024/03/Shantha-Selva-Kumari.png');"> </div> <div class="modal-title"> <p class="member-title"><span class="member-name">Name </span> : Wei Li</p> <p class="member-university"><span class="member-uni">University </span> : </p> <p class="member-country"><span class="modal-title-heading">Country </span> : USA</p> </div> <button type="button" class="btn-close" data-bs-dismiss="modal"></button> </div> <div class="modal-body"> <p><strong>Abstract:<br /> </strong></p> <p style="text-align: left;">Sperm-associated antigen 6 (SPAG6) is the mammalian orthologue of <em>Chlamydomonas</em> PF16, a protein localizing within the central pair of the axoneme and involved in flagellar motility of the algae. In mice, two <em>Spag6</em> genes have been identified. The ancestral gene, located on mouse chromosome 2, is named <em>Spag6</em>. A related gene, located on mouse chromosome 16 and evolved from the ancient <em>Spag6</em> gene, has been named <em>Spag6</em>-like (<em>Spag6l</em>). Global <em>Spag6</em> knockout mice (C57 background) are grossly normal, and fertility was not shown to be affected in both males and females. In particular, the homozygous males had normal sperm parameters, including sperm count, motility, and morphology. Examination of testis histology also revealed normal spermatogenesis. In contrast, the global <em>Spag6l</em> knockout mouse model (C57 background) was previously generated and showed lethality. Most homozygous <em>Spag6l</em> knockout mice died before 4-weeks of age; the few males which survived to sexual maturity were infertile, and the fertility of the females was also affected. However, fertility of the heterozygous <em>Spag6l</em> knockout mice was normal. We have crossed the two knockout lines to generate <em>Spag6</em>/<em>Spag6l</em> double knockout mice. The compound heterozygous (<em>Spag6</em><sup>+/-</sup>; <em>Spag6l</em><sup>+/-</sup>) mice showed normal fertility, and all the mice carrying Spag6l homozygous mutation (<em>Spag6l</em><sup>-/-</sup>), either with heterozygous (<em>Spag6</em><sup>+/-</sup>) or homozygous (<em>Spag6</em><sup>-/-</sup>) <em>Spag6</em> mutation died before 4-weeks of age. However, even though all <em>Spag6</em><sup>-/-</sup>; <em>Spag6l</em><sup>+/-</sup> mice were grossly normal, all the males were completely infertile. Compared to the controls (<em>Spag6</em><sup>-/-</sup>; <em>Spag6</em>l<sup>+/+</sup> or <em>Spag6</em><sup>+/-</sup>; <em>Spag6l</em><sup>+/-</sup>) males, the <em>Spag6</em><sup>-/-</sup>; <em>Spag6l</em><sup>+/-</sup> males had significantly reduced sperm number, and the sperm that were formed were morphologically abnormal and motility was significantly reduced. Histologic examination of the testes by light microscopy also revealed impaired spermiogenesis. Analysis by Transmission Electron Microscopy revealed abnormal sperm ultrastructure with both head/chromatin and tail formation defects. The <em>Spag6</em><sup>-/-</sup>; <em>Spag6l</em><sup>+/-</sup> females sired normal number of pups compared to the control females but the time from breeding to delivery was longer than normal, suggesting gestation defects. Overall, our findings indicate that in mouse, both genes, <em>Spag6</em> and <em>Spag6l</em>, coordinate to modulate sperm formation and male fertility and are also likely required for proper female fertility.</p> <p><strong> </strong></p> </div> <div class="modal-footer"> <button type="button" class="btn btn-danger" data-bs-dismiss="modal">Close</button> </div> </div> </div> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-5a86f71 elementor-align-center elementor-widget elementor-widget-button" data-id="5a86f71" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://cognitionconferences.com/cellscience/speakers/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-long-arrow-alt-right"></i> </span> <span 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