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Accelerate your research. Let BioAgilytix help you meet the different vaccines quality requirements in all production stages." /><link rel="canonical" href="https://www.bioagilytix.com/solutions/modalities/vaccine-development/" /><meta property="og:locale" content="en_US" /><meta property="og:type" content="article" /><meta property="og:title" content="Vaccine Development | BioAgilytix" /><meta property="og:description" content="Streamline your vaccine development. Accelerate your research. 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-o-transition-property: border-color; transition-property: border-color; } /* Style new checked item */ ul.inputs-list.multi-container li.hs-form-checkbox label span::after, .hs-form-booleancheckbox-display span::after { content: ""; border: 2px solid #d9d9d9; border-radius: 3px; height: 20px; left: 0px; position: absolute; top: 0px; width: 20px; background: #fff; z-index: 0; display: block; transition-property: background-color, border-color, -webkit-box-shadow; -o-transition-property: background-color, border-color, box-shadow; transition-property: background-color, border-color, box-shadow; transition-property: background-color, border-color, box-shadow, -webkit-box-shadow; } /* Show when checked */ ul.inputs-list.multi-container li.hs-form-checkbox label input:checked + span::after, .hs-form-booleancheckbox-display input:checked + span::after, ul.inputs-list.multi-container li.hs-form-checkbox label input:checked + span::before, .hs-form-booleancheckbox-display input:checked + span::before{ opacity: 1; } .hs-form-booleancheckbox-display input:checked+label:after, .hs-form-booleancheckbox-display input:checked+label:after { background: #fff; border-color: #157479; } /* Style when focused */ ul.inputs-list.multi-container li.hs-form-checkbox label input:focus + span::after, .hs-form-booleancheckbox-display input:focus + span::after { outline: 3px solid transparent; /* For Windows high contrast mode. */ box-shadow: 0 0 .3125rem rgba(0, 0, 0, .3); border-color: #157479; } .hs_contact_country{ clear: both; } .hs-button { border-radius: 65px !important; font-size: 14px; line-height: 1.3; letter-spacing: 1.12px; font-family: "Roboto Slab", helvetica, arial, sans-serif; font-weight: 700 !important; padding: 19px 23px !important; border: 2px solid; display: inline-block; text-decoration: none; text-transform: uppercase; -webkit-appearance: none !important; -moz-appearance: none !important; appearance: none !important; } .hbspt-form textarea{max-width: 100% !important; height: 186px !important; resize: none;} .hbspt-form textarea:focus{border: 1px solid #74cbc8 !important;} .hs-fieldtype-textarea .invalid.error{border: 2px solid #E74949 !important;} .hbspt-form fieldset{max-width: 100% !important; margin-bottom: 60px;} .hbspt-form .field {margin-bottom: 27px} .hs_recaptcha{ margin-top: 23px !important; margin-bottom: 27px !important; } .hs-button, .hs-form-field input[type=text], .hs-form-field input[type=email], .hs-form-field input[type=phone], .hs-form-field input[type=number], .hs-form-field input[type=tel], .hs-form-field input[type=date], .hs-form-field textarea { appearance: none; -webkit-appearance: none; -moz-appearance: none; } .hs-default-font-element, .hs-main-font-element { font-family: "Roboto Slab", helvetica, arial, sans-serif; } .hbspt-form .hs-button { white-space: pre-wrap } .hbspt-form .hs-richtext { word-break: break-word } .hbspt-form.submitted-message { overflow: auto } .hbspt-form fieldset.form-columns-1 .hs-input { width: 95% } .hbspt-form fieldset.form-columns-1 .input { margin-right: 0px !important } .hbspt-form fieldset.form-columns-1 input[type=checkbox], .hbspt-form fieldset.form-columns-1 input[type=radio] { width: auto } .hbspt-form fieldset.form-columns-2 .hs-form-field { width: 50%; float: left } .hbspt-form fieldset.form-columns-2 .input { margin-right: 0px !important; } .hbspt-form fieldset.form-columns-3 .hs-form-field { width: 32.7%; float: left } .hbspt-form fieldset.form-columns-3 .input { margin-right: 8px } .hbspt-form label.hs-hidden { visibility: hidden } .hbspt-form .hs-field-desc { width: 100% } .hs-custom-style .hs-input, .hs-custom-style fieldset { max-width: 100% } .hs-custom-style>div.form-columns-3 .hs-form-field, .hs-custom-style fieldset.form-columns-3 .hs-form-field { width: 33.3% } .hs-custom-style>div>div:last-of-type .hs-input:not([type=checkbox]):not([type=radio]), .hs-custom-style fieldset>div:last-of-type .hs-input:not([type=checkbox]):not([type=radio]) { width: 100%; max-width: 100% } .hs-custom-style>div input:not([type=image]):not([type=submit]):not([type=button]):not([type=radio]):not([type=checkbox]):not([type=file]), .hs-custom-style fieldset input:not([type=image]):not([type=submit]):not([type=button]):not([type=radio]):not([type=checkbox]):not([type=file]) { box-sizing: border-box; padding: 0 15px; min-height: 27px } .hs-custom-style>div textarea, .hs-custom-style fieldset textarea { padding: 10px 15px } .hs-custom-style .hs-dependent-field>div .hs-input:not([type=checkbox]):not([type=radio]) { width: 100% } .legal-consent-container .field.hs-form-field { margin-bottom: 8px } .legal-consent-container .hs-field-desc.checkbox-desc { margin: -12px 0 0 21px } .legal-consent-container .hs-form-booleancheckbox-display input { float: left } .legal-consent-container .hs-form-booleancheckbox-display>span { display: block !important; margin-left: 30px !important; } .legal-consent-container .hs-form-booleancheckbox-display p { margin: 0; display: inline } .legal-consent-container .hs-error-msgs label { color: #f2545b } .legal-consent-container~.hs_recaptcha { margin-top: 18px } .cookie-reset-container { font-size: 14px; margin-bottom: 10px; text-align: right } #hs-outer-captcha-target, #hs-outer-captcha-target * { display: none; height: 0; width: 0 } .hubspot-link__container { font-size: 14px; padding-bottom: 40px; position: relative; color: #9fa0a2; font-family: "Roboto Slab", helvetica, arial, sans-serif; } .hubspot-link-text { color: #00a4bd; font-weight: 400 } .hubspot-link__container.sproket { color: #9fa0a2 } .hubspot-link { color: #9fa0a2 } .hubspot-link, .hubspot-link:hover { text-decoration: none } .hubspot-link:hover .hubspot-link-text { text-decoration: underline } .hubspot-link__icon { margin-bottom: -1px; margin-right: 5px } .hubspot-link__container.sproket .hubspot-link__icon { width: 30px; margin-right: 0; float: left; margin-top: -9px; margin-left: -5px } .hubspot_signup_form .hs_email{margin-bottom: 0px !important; width: 80% !important; float: left !important;} .hubspot_signup_form .hs_submit{width: 20% !important; float: left !important; } .hubspot_signup_form .hs-button{padding: 12.5px 15px !important;} .hubspot_signup_form .hs_email label{display: none !important;} .hubspot_signup_form ul.no-list{position: absolute !important; top: 48px !important;} .hubspot_signup_form {position: relative !important;} .hubspot_signup_form .submitted-message{color: #ab8940 !important; font-size: 22px !important; } .hubspot_white .hbspt-form label, .hubspot_white .hs-form-required { color: #fff; } .hubspot_white .hs-input, .hubspot_white ul.inputs-list.multi-container li.hs-form-checkbox label span::before, .hubspot_white .hs-form-booleancheckbox-display span::before{ background-color: #fff !important; } .hubspot_white .hs_submit { text-align: center; } .hubspot_white .hs-form select.is-placeholder { opacity: 1; } .hubspot_white ul.inputs-list.multi-container li.hs-form-checkbox label span::after, .hubspot_white .hs-form-booleancheckbox-display span::after { border-color: #3f4852; } input[type=submit].hs-button.primary.large{ color: #fff; background: #00181e; border-color: #00181e !important; } input[type=submit].hs-button.primary.large:hover { background: #74cbc8 !important; border-color: #74cbc8 !important; } /***/ .hbspt-form .hs-input[type=checkbox]{ cursor: pointer; } .hs-form-booleancheckbox-display input:checked + span::after{ background: #fff; border-color: #157479; } .hbspt-form .form-columns-2 { display: flex; flex-flow: row wrap; -webkit-box-direction: normal; } .hbspt-form .hs_firstname { flex: 1; -webkit-box-flex: 1; } .hbspt-form .hs_submit{ margin-top: 60px; } .newsletter-form .hs_submit{margin-top: 45px;} .newsletter-form form .gfield_consent_description { border: none !important; } /*New Landing page*/ .landing-middle-section{ padding-right: 0px !important; } .left-col{max-width:93%} .left-col-para{padding-right:30px;} .left-col video{border-radius:4px;} /* Kit asssesment */ .kits_form_col .hbspt-form .hs-input[type=checkbox] { height: 20px !important; width: 20px !important; } .kits_form_col {padding-bottom: 45px;} .hs-richtext h4 {margin-bottom: 15px !important;} .kits_form_col label.hs-form-checkbox-display {margin-bottom: 15px;} .kits_form_col .hbspt-form li.hs-form-checkbox label span{ margin-left: 0px !important; padding-left: 31px; } .hbspt-form label.hs-form-radio-display { position: relative; padding: 4px 31px; } .hbspt-form .hs-form-radio-display span, .hbspt-form .hs-form-checkbox-display span { position: relative; cursor: pointer; font-size: 15px; font-weight: 300; } .hbspt-form .hs-input[type=radio] { position: absolute; left: 0; z-index: 2; width: 20px !important; height: 20px !important; outline: none; cursor: pointer; background-color: transparent !important; border-radius: 50%; } .hbspt-form .hs_protocol_synopsis_upload .input{position: relative;} .hbspt-form input[type="file"]::-webkit-file-upload-button { cursor: pointer; background-color: #157479; padding: 10px 20px !important; border: 1px solid #157479; border-top-left-radius: 0px; border-bottom-left-radius: 0px; border-top-right-radius: 6px; border-bottom-right-radius: 6px; color: #fff; position: absolute; top: 0; bottom: 0; right: 0; } .hbspt-form input[type="file"] { cursor: pointer; padding: 10px 20px !important; position: relative; top: 0; bottom: 0; right: 0; } /*Form Responsive CSS*/ @media only screen and (min-width: 1024px) and (max-width: 1366px){ .hs_email, .hs_contact_country { clear: both; } } @media only screen and (min-width: 992px) and (max-width: 1024px){ .hs_email, .hs_contact_country { clear: both; } } @media (min-width: 640px) and (max-width: 1120px) { .hbspt-form h1{font-size: 36px !important;} } @media screen and (min-width: 1120px) { .hbspt-form h1{font-size: 45px !important;margin-bottom: 17px !important;} .hbspt-form .gform_heading p{font-size: 17px !important;} } @media only screen and (min-width: 768px) and (max-width: 992px){ .hs_email, .hs_contact_country{ clear: both; } } @media (min-width: 767px) and (max-width: 1024px) { body .hubspot_signup_form .hs_email{width: 66% !important; float: left !important;} } @media screen and (max-width: 992px){ .assay-kit-hbspt-form .fl-col { width: 100%; } } @media screen and (max-width:812px){ .assay-kit-hbspt-form .fl-col { max-width: 100%; } .hbspt-form .hs-fieldtype-select .input:before{ right: 20px !important; } } @media screen and (max-width: 767px){ .hs_submit .actions{padding-top: 0px !important; margin-top: 0px !important;} body .hbspt-form fieldset.form-columns-2 .input {margin-right: 0px !important;} body fieldset.form-columns-3 .input{margin-right: 0px !important;} .hs-form-field .hs-input { width: 100% !important; } .hs-fieldtype-textarea .input{margin-right: 0px !important;} .hs_firstname, .hs_phone, .hs_development_area{ width: 100% !important; } } @media screen and (min-width: 640px){ .hbspt-form .hs_firstname, .kits_form_col .hs_email{ padding-right: 10px; } .hbspt-form .hs-lastname, .kits_form_col .hs_confirm_email{ padding-left: 10px; } .kits_form_col {padding-bottom: 108px;} .hs-richtext h4 {margin-bottom: 30px !important;} .kits_form_col label.hs-form-checkbox-display {margin-bottom: 20px;} } @media screen and (max-width: 640px){ .hbspt-form h1{font-size: 32px !important;} .hbspt-form .gform_heading p{font-size: 16px !important;} .hbspt-form .form-columns-2 .field{ -webkit-box-flex: 0; -ms-flex: 0 0 100%; flex: 0 0 100%; margin-bottom: .5rem; padding-left: 0; } } @media screen and (max-width: 540px){ .event-hero-section > div{ justify-items: flex-start !important; } } @media screen and (max-width: 414px){ body .hubspot_signup_form .hs_email {width: 66% !important;} body .hubspot_signup_form ul.no-list{top: 65px !important;} } @media screen and (max-width: 320px){ body .hubspot_signup_form .hs_email {width: 61% !important;} }</style> <style type="text/css">.about-presenter-section{display:none;} .space-hero-section{margin-bottom:0px !important;} .partner_bioAgilytix {padding-right: 2.5rem !important;} @media screen and (max-width: 540px){ .event-hero-section > div{ justify-items: flex-start !important; } }</style> <style type="text/css">/* Add your CSS code here. 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masthead__title">Vaccines</div><div class="masthead__content-body"><h1>Vaccine Development: Advancements and Challenges</h1></div></div><div class="breadcrumbs"><span><span><a href="https://www.bioagilytix.com/"><i class="home-icon"></i><span class="screen-reader-text">Home</span></a></span> <span class="breadcrumb-separator"></span> <span><a href="https://www.bioagilytix.com/solutions/">Solutions</a></span> <span class="breadcrumb-separator"></span> <span><a href="https://www.bioagilytix.com/solutions/modalities/">Modalities</a></span> <span class="breadcrumb-separator"></span> <span class="breadcrumb_last" aria-current="page">Vaccines</span></span></div></div></section><div class="wp-block-group alignwide is-layout-constrained wp-container-core-group-is-layout-1 wp-block-group-is-layout-constrained"><p class="has-text-align-center has-large-font-size">Vaccine development is one of the most diverse and fastest growing areas in pharmaceuticals and biotechnology. The serious impacts of infectious diseases like Ebola, Malaria, HIV, and COVID-19 on world health have continued to make vaccines.</p></div><div class="wp-block-emagine-background alignfull has-em-white-background-color has-background-dim em-pt--lg em-pb--lg em-mt--lg em-mb--none"><div class="wp-block-emagine-background__content"><div class="wp-block-emagine-background__content-inner"><div class="wp-block-emagine-grid alignwide wp-block-emagine-grid--halves"><div class="wp-block-emagine-grid__inner em-grid-2_sm-1-equalHeight-left"><div class="wp-block-emagine-column em-col"><h2 class="h2">Vaccine development: support for a broad range of formats</h2><p class="">BioAgilytix’s deep experience in cell-based assays, immunology, and potency assay development for biologics enables us to effectively collaborate with sponsors on complex bioanalytical assessments for<s> </s>various vaccine. Generation 1 vaccines, which are infectious agent-based, still hold a significant position in disease prevention and require bioanalytical support strategies to provide characterization of immunologic responses. Our expertise in developing a range of immune-based methods on a broad set of platforms allows us to efficiently develop these assays under GLP, GCLP, and GMP regulatory expectations. </p><p class="">The development of Generation 2 and 3 vaccines, which can include recombinant proteins, virus-like particles (VLPs), nucleic acid- or vector-based vaccines, and emerging virus neutralization approaches such as monoclonal antibodies directed at the target virus, have grown significantly owing to their relative control, reduced risk, and targeted effectiveness. Early pre-clinical testing of these vaccine product and characterization of immune responses is traditionally supported using animal models<s>.</s> Industry focus to address the ‘3Rs‘ – replace, reduce, refine – to minimize the use of animal testing has resulted in a shift from large scale animal testing to implementation of various potency and mechanistic assays which can be performed in vitro<s> </s>using immune-based methods. Additionally, cell-based assays using cell lines or primary cells are typically required to demonstrate mode of action (i.e. particle or protein interaction with a target cell) during vaccine development.</p></div><div class="wp-block-emagine-column em-col"><div class="wp-block-image size-full"><div><figure class=""><img fetchpriority="high" decoding="async" width="1000" height="987" src="https://www.bioagilytix.com/wp-content/uploads/2023/08/shutterstock_1698967894.png" alt="" class="wp-image-3249" srcset="https://www.bioagilytix.com/wp-content/uploads/2023/08/shutterstock_1698967894.png 1000w, https://www.bioagilytix.com/wp-content/uploads/2023/08/shutterstock_1698967894-300x296.png 300w, https://www.bioagilytix.com/wp-content/uploads/2023/08/shutterstock_1698967894-768x758.png 768w, https://www.bioagilytix.com/wp-content/uploads/2023/08/shutterstock_1698967894-100x99.png 100w" sizes="(max-width: 1000px) 100vw, 1000px" /></figure></div></div></div></div></div></div></div></div><div class="wp-block-emagine-grid alignwide wp-block-emagine-grid--halves em-mt--md em-mb--md"><div class="wp-block-emagine-grid__inner em-grid-2_sm-1-left-middle"><div class="wp-block-emagine-column em-col-middle"><div class="wp-block-image size-full"><div><figure class=""><noscript><img decoding="async" width="1000" height="971" src="https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell.png" alt="" class="wp-image-3259" srcset="https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell.png 1000w, https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell-300x291.png 300w, https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell-768x746.png 768w, https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell-100x97.png 100w" sizes="(max-width: 1000px) 100vw, 1000px" /></noscript><img decoding="async" width="1000" height="971" src='data:image/svg+xml,%3Csvg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%201000%20971%22%3E%3C/svg%3E' data-src="https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell.png" alt="" class="lazyload wp-image-3259" data-srcset="https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell.png 1000w, https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell-300x291.png 300w, https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell-768x746.png 768w, https://www.bioagilytix.com/wp-content/uploads/2023/08/virus-cell-100x97.png 100w" data-sizes="(max-width: 1000px) 100vw, 1000px" /></figure></div></div></div><div class="wp-block-emagine-column em-col-middle"><h2 class="h2">Assessments</h2><p class="">BioAgilytix, working with an array of both emerging and large pharmabio customers, provides robust, compliant bioanalytical assessments for the diverse range of vaccine varieties in development today. With leading expertise in complex biologics and a broad suite of advanced platforms, we can apply the optimal, phase-appropriate method to meet your unique vaccine program needs. </p></div></div></div><div id="block_c1b73cb6b20e5aece3f117d58b4a31cf" class="wp-block em-media-content em-mt--md em-mb--sm alignfull"><div class="em-media-content__inner em-media-content__inner--media-right has-gray-xxl-background-color em-media-content__inner--content-has-padding"><div class="em-media-content__media em-media-content__media--right"> <noscript><img decoding="async" src="https://www.bioagilytix.com/wp-content/uploads/2023/08/square-image-template-1200x776.jpg" alt="scientist on tablet" class="object-fit--cover" srcset="" width="1200" height="776"></noscript><img decoding="async" src='data:image/svg+xml,%3Csvg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%201200%20776%22%3E%3C/svg%3E' data-src="https://www.bioagilytix.com/wp-content/uploads/2023/08/square-image-template-1200x776.jpg" alt="scientist on tablet" class="lazyload object-fit--cover" data-srcset="" width="1200" height="776"></div><div class="em-media-content__content em-media-content__content--left em-media-content__content--add-padding"><div class="wp-block-emagine-spacer wp-block-emagine-spacer--md" aria-hidden="true"></div><h2 class="h2">Expertise</h2><p class="">BioAgilytix’s GLP, GCLP, and GMP staff have more than 100 years of collective experience in developing immune-based methods and cell-based assays to measure potency, efficacy, and safety endpoints which we leverage in testing for a myriad of vaccine types. We validate assays to ICH standards and apply phase-appropriate criteria to support your vaccine program lifecycle from early phase development through pre-commercial/Phase III efforts. We’ll work closely to define your specific assay requirements and facilitate selection of the best platform for everything from short-term feasibility studies to long-term robust product release testing. </p><div class="wp-block-emagine-spacer wp-block-emagine-spacer--md" aria-hidden="true"></div></div></div></div><div class="wp-block-emagine-background alignfull has-gray-xxl-background-color has-background-dim em-mt--lg"><div class="wp-block-emagine-background__content"><div class="wp-block-emagine-background__content-inner"></div></div></div><h2 class="h2">Full range of phase appropriate methods for vaccine assessments</h2><p class="">Our experience is deep across the range of assays below performed under GxP regulations. Through these comprehensive assessments we are able to help ensure your vaccine products are well-positioned to successfully advance down the development and approval pathways. </p><div class="wp-block-emagine-grid alignwide wp-block-emagine-grid--quarters em-mt--md em-mb--md"><div class="wp-block-emagine-grid__inner em-grid-4_sm-2_xs-1-smGutter-left"><div class="wp-block-emagine-column em-col"><div id="block_8f2bea04a9300cea2eefa4860da689f4" class="wp-block em-icon-content aligndefault"><div class="em-icon-content__container align--left"><div class="em-icon-content__icon has-primary-l-background-color""> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="60px" height="52px" viewBox="0 0 60 52" version="1.1" class=""><title>002 – Laptop Dashboard</title> <desc>Created with Sketch.</desc> <defs></defs> <g id="6745a9c2e4c85-Page-1" stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g id="6745a9c2e4c85-002---Laptop-Dashboard" fill="#000000" fill-rule="nonzero"> <path d="M7,52 L53,52 C56.86,52 60,48.86 60,45 L60,42 C60,40.897 59.103,40 58,40 L58,5 C58,2.243 55.757,0 53,0 L7,0 C4.243,0 2,2.243 2,5 L2,40 C0.897,40 0,40.897 0,42 L0,45 C0,48.86 3.14,52 7,52 Z M4,5 C4,3.346 5.346,2 7,2 L53,2 C54.654,2 56,3.346 56,5 L56,40 L4,40 L4,5 Z M21,42 L39,42 L39,43 C39,44.103 38.103,45 37,45 L23,45 C21.897,45 21,44.103 21,43 L21,42 Z M2,42 L19,42 L19,43 C19,45.206 20.794,47 23,47 L37,47 C39.206,47 41,45.206 41,43 L41,42 L58,42 L58,45 C58,47.757 55.757,50 53,50 L7,50 C4.243,50 2,47.757 2,45 L2,42 Z" id="6745a9c2e4c85-Shape"></path> <path d="M13,46 L16,46 C16.552,46 17,45.552 17,45 C17,44.448 16.552,44 16,44 L13,44 C12.448,44 12,44.448 12,45 C12,45.552 12.448,46 13,46 Z"></path> <circle id="6745a9c2e4c85-Oval" cx="5" cy="45" r="1"></circle> <circle cx="9" cy="45" r="1"></circle> <path d="M9,23 L30,23 C30.552,23 31,22.552 31,22 C31,21.448 30.552,21 30,21 L29,21 L29,14 C29,12.897 28.103,12 27,12 L25,12 L25,9 C25,7.897 24.103,7 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id="block-b458d5cb-58c0-4d39-876e-ec51e872b5de">Neutralizing Antibodies (NAb) </p><p class="" id="block-5a4e511e-fbd5-49ef-b86a-95893c7de8a3">Potency Assays </p></div></div></div></div><div class="wp-block-emagine-column em-col"><div id="block_e1dfec9e1eb0a35d51b04cb156dbdbb4" class="wp-block em-icon-content aligndefault"><div class="em-icon-content__container align--left"><div class="em-icon-content__icon has-primary-l-background-color""> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="60px" height="60px" viewBox="0 0 60 60" version="1.1" class=""><title>017 – Chromosomes</title> <desc>Created with Sketch.</desc> <defs></defs> <g id="6745a9c2e5862-Page-1" stroke="none" stroke-width="1" fill="none" fill-rule="evenodd" stroke-linecap="round" stroke-linejoin="round"> <g id="6745a9c2e5862-017---Chromosomes" transform="translate(1.000000, 1.000000)" stroke="#000000" stroke-width="2"> <path d="M38,21 C38,19.3431458 36.6568542,18 35,18 C33.3431458,18 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class=""></p></div></div></div></div><div class="wp-block-emagine-column em-col"><div id="block_a0e704d9452b84e0d3bff79da9ab3da0" class="wp-block em-icon-content aligndefault"><div class="em-icon-content__container align--left"><div class="em-icon-content__icon has-primary-l-background-color""> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="60px" height="60px" viewBox="0 0 60 60" version="1.1" class=""><title>020 – DNA Research</title> <desc>Created with Sketch.</desc> <defs></defs> <g id="6745a9c2e5c13-Page-1" stroke="none" stroke-width="1" fill="none" fill-rule="evenodd" stroke-linecap="round" stroke-linejoin="round"> <g id="6745a9c2e5c13-020---DNA-Research" transform="translate(1.000000, 1.000000)" stroke="#000000" stroke-width="2"> <path d="M11,32 C8.24,32 6,34.54 6,37.67 C6,40.8 8.24,43.33 11,43.33 C13.76,43.33 16,40.79 16,37.67 C16,34.55 13.76,32 11,32 Z M18.37,46.33 C20.3514149,44.4024888 21.6025799,41.8471435 21.91,39.1 L18.37,46.33 Z" 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aligndefault"><div class="em-icon-content__container align--left"><div class="em-icon-content__icon has-primary-l-background-color""> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="60px" height="60px" viewBox="0 0 60 60" version="1.1" class=""><title>069 – Virus Dish</title> <desc>Created with Sketch.</desc> <defs></defs> <g id="6745a9c2e6028-Page-1" stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g id="6745a9c2e6028-069---Virus-Dish" fill="#000000" fill-rule="nonzero"> <path d="M30,0 C13.4314575,-1.01453063e-15 2.02906125e-15,13.4314575 0,30 C-2.02906125e-15,46.5685425 13.4314575,60 30,60 C46.5685425,60 60,46.5685425 60,30 C59.981263,13.4392249 46.5607751,0.0187370435 30,0 Z M30,58 C14.536027,58 2,45.463973 2,30 C2,14.536027 14.536027,2 30,2 C45.463973,2 58,14.536027 58,30 C57.9823655,45.4566626 45.4566626,57.9823655 30,58 Z" id="6745a9c2e6028-Shape"></path> <path d="M30,4 C15.6405965,4 4,15.6405965 4,30 C4,44.3594035 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class="em-icon-content__content"><h4 class="h4">Virology </h4><p class="">Plaque reduction neutralization test (PRNT) </p><p class="">Plaque assay (PA) </p><p class="">Quantitative (TCID50) and qualitative culture (flask) virus subtyping </p><p class="">Microneutralization </p><p class="">Resistance characterization </p><p class="">Hemagglutinin inhibition (HAI) </p><p class=""></p></div></div></div></div></div></div><div id="block_da055db1ed5d28611a3e542542c1ad30" class="wp-block em-media-content em-mt--md em-mb--none alignfull"><div class="em-media-content__inner em-media-content__inner--media-right has-gray-xxl-background-color em-media-content__inner--content-has-padding"><div class="em-media-content__media em-media-content__media--right"> <noscript><img decoding="async" src="https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-1380x776.jpg" alt="vaccines" class="object-fit--cover" srcset="https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-1380x776.jpg 1380w, https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-2000x1125.jpg 2000w, https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-1120x630.jpg 1120w, https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-850x478.jpg 850w, https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-640x360.jpg 640w" width="1380" height="776"></noscript><img decoding="async" src='data:image/svg+xml,%3Csvg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%201380%20776%22%3E%3C/svg%3E' data-src="https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-1380x776.jpg" alt="vaccines" class="lazyload object-fit--cover" data-srcset="https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-1380x776.jpg 1380w, https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-2000x1125.jpg 2000w, https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-1120x630.jpg 1120w, https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-850x478.jpg 850w, https://www.bioagilytix.com/wp-content/uploads/2023/08/dna-strand-640x360.jpg 640w" width="1380" height="776"></div><div class="em-media-content__content em-media-content__content--left em-media-content__content--add-padding"><h2 class="h2"><strong>Optimal platforms for vaccine assays: plate-based methods</strong></h2><p class="">The science behind vaccines has advanced substantially in recent years – as have regulatory expectations. Potency assays have evolved from simple titers to relative potency determinations to demonstrate appropriate control of the product. The 3Rs initiative is also driving more vaccine testing to move from in vivo animal models to in vitro using epitope-targeted ELISAs or cell-based assays with immune-pertinent systems. </p><p class="">BioAgilytix’s expertise in developing a range of ELISA and cell-based assays for biologics and gene & cell therapies on a broad set of platforms, paired with our specialization in immunology and with ADA and NAb assays, ensures your vaccine products are well-positioned to successfully advance down the development and approval pathways. </p></div></div></div></article></main><footer class="site-footer site-footer--has-logo site-footer--align-brand-left"><div class="deep-footer clearfix"><div class="alignwide"><div class="em-grid"><div class="em-col-6_md-12"><div class="deep-footer__brand"><div class="deep-footer__logo" style="max-width: 300px"> <a href="https://www.bioagilytix.com"><div class="em-image"><div class="em-image__ratio" style="padding-top:21.420572708367%;"> <svg 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