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class="vector-toc-numb">2</span> <span>Interactions</span> </div> </a> <ul id="toc-Interactions-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Associated_genetic_disorders" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Associated_genetic_disorders"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Associated genetic disorders</span> </div> </a> <button aria-controls="toc-Associated_genetic_disorders-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Associated genetic disorders subsection</span> </button> <ul id="toc-Associated_genetic_disorders-sublist" class="vector-toc-list"> <li id="toc-Beta_thalassemia" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Beta_thalassemia"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.1</span> <span>Beta thalassemia</span> </div> </a> <ul id="toc-Beta_thalassemia-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Sickle_cell_disease" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Sickle_cell_disease"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.2</span> <span>Sickle cell disease</span> </div> </a> <ul id="toc-Sickle_cell_disease-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Haemoglobin_C" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Haemoglobin_C"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.3</span> <span>Haemoglobin C</span> </div> </a> <ul id="toc-Haemoglobin_C-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Haemoglobin_E" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Haemoglobin_E"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.4</span> <span>Haemoglobin E</span> </div> </a> <ul id="toc-Haemoglobin_E-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Human_evolution" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Human_evolution"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Human evolution</span> </div> </a> <ul id="toc-Human_evolution-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Further_reading" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Further_reading"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Further reading</span> </div> </a> <ul id="toc-Further_reading-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav 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class="firstHeading mw-first-heading"><span class="mw-page-title-main">Hemoglobin subunit beta</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. 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hreflang="bs" data-title="HBB" data-language-autonym="Bosanski" data-language-local-name="Bosnian" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/%CE%92-Globin" title="Β-Globin – German" lang="de" hreflang="de" data-title="Β-Globin" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/HBB" title="HBB – Spanish" lang="es" hreflang="es" data-title="HBB" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/HBB" title="HBB – Basque" lang="eu" hreflang="eu" data-title="HBB" data-language-autonym="Euskara" data-language-local-name="Basque" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Subunidade_beta_da_hemoglobina" title="Subunidade beta da hemoglobina – Galician" lang="gl" hreflang="gl" data-title="Subunidade beta da hemoglobina" data-language-autonym="Galego" data-language-local-name="Galician" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%AC%E0%A5%80%E0%A4%9F%E0%A4%BE-%E0%A4%97%E0%A5%8D%E0%A4%B2%E0%A5%8B%E0%A4%AC%E0%A4%BF%E0%A4%A8" title="बीटा-ग्लोबिन – Hindi" lang="hi" hreflang="hi" data-title="बीटा-ग्लोबिन" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Subunit_hemoglobin_beta" title="Subunit hemoglobin beta – Malay" lang="ms" hreflang="ms" data-title="Subunit hemoglobin beta" data-language-autonym="Bahasa Melayu" data-language-local-name="Malay" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%91%D0%B5%D1%82%D0%B0-%D0%B3%D0%B5%D0%BC%D0%BE%D0%B3%D0%BB%D0%BE%D0%B1%D1%96%D0%BD" title="Бета-гемоглобін – Ukrainian" lang="uk" hreflang="uk" data-title="Бета-гемоглобін" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q424422#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> 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data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">"HBB" redirects here. For other uses, see <a href="/wiki/HBB_(disambiguation)" class="mw-disambig" title="HBB (disambiguation)">HBB (disambiguation)</a>.</div> <table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">HBB</th></tr><tr><td colspan="4" style="text-align:center"><span typeof="mw:File"><a href="/wiki/File:Protein_HBB_PDB_1a00.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Protein_HBB_PDB_1a00.png/250px-Protein_HBB_PDB_1a00.png" decoding="async" width="250" height="216" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Protein_HBB_PDB_1a00.png/375px-Protein_HBB_PDB_1a00.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Protein_HBB_PDB_1a00.png/500px-Protein_HBB_PDB_1a00.png 2x" data-file-width="929" data-file-height="804" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Available structures</th></tr><tr><th rowspan="2" style="background-color:#c3fdb8;width:43px"><a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a></th><td colspan="2" style="background-color:#eee">Ortholog search: <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/searchResults.html?display=both&term=P02088%20or%20P68871">PDBe</a> <a rel="nofollow" class="external text" href="https://www.rcsb.org/search?q=rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_name:UniProt%20AND%20rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_accession:P02088,P68871">RCSB</a> </span></td></tr><tr><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr style="background-color:#ddd;text-align:center"><th colspan="2">List of PDB id codes</th></tr><tr><td colspan="2" style="background-color:#eee"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/6HBW">6HBW</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1A00">1A00</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1A01">1A01</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1A0U">1A0U</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1A0Z">1A0Z</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1A3N">1A3N</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1A3O">1A3O</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1ABW">1ABW</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1ABY">1ABY</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1AJ9">1AJ9</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1B86">1B86</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1BAB">1BAB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1BBB">1BBB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1BIJ">1BIJ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1BUW">1BUW</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1BZ0">1BZ0</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1BZ1">1BZ1</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1BZZ">1BZZ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1C7B">1C7B</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1C7C">1C7C</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1C7D">1C7D</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1CBL">1CBL</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1CBM">1CBM</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1CH4">1CH4</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1CLS">1CLS</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1CMY">1CMY</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1COH">1COH</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1DKE">1DKE</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1DXT">1DXT</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1DXU">1DXU</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1DXV">1DXV</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1FN3">1FN3</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1G9V">1G9V</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1GBU">1GBU</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1GBV">1GBV</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1GLI">1GLI</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1GZX">1GZX</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HAB">1HAB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HAC">1HAC</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HBA">1HBA</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HBB">1HBB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HBS">1HBS</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HCO">1HCO</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HDB">1HDB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HGA">1HGA</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HGB">1HGB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HGC">1HGC</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HHO">1HHO</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1IRD">1IRD</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1J3Y">1J3Y</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1J3Z">1J3Z</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1J40">1J40</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1J41">1J41</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1J7S">1J7S</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1J7W">1J7W</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1J7Y">1J7Y</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1JY7">1JY7</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1K0Y">1K0Y</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1K1K">1K1K</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1KD2">1KD2</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LFL">1LFL</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LFQ">1LFQ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LFT">1LFT</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LFV">1LFV</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LFY">1LFY</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LFZ">1LFZ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1LJW">1LJW</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1M9P">1M9P</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1MKO">1MKO</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1NEJ">1NEJ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1NIH">1NIH</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1NQP">1NQP</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1O1I">1O1I</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1O1J">1O1J</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1O1K">1O1K</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1O1L">1O1L</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1O1M">1O1M</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1O1N">1O1N</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1O1O">1O1O</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1O1P">1O1P</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1QI8">1QI8</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1QSH">1QSH</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1QSI">1QSI</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1QXD">1QXD</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1QXE">1QXE</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1R1X">1R1X</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1R1Y">1R1Y</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1RPS">1RPS</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1RQ3">1RQ3</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1RQ4">1RQ4</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1RQA">1RQA</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1RVW">1RVW</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1SDK">1SDK</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1SDL">1SDL</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1THB">1THB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1UIW">1UIW</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1VWT">1VWT</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XXT">1XXT</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XY0">1XY0</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XYE">1XYE</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XZ2">1XZ2</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XZ4">1XZ4</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XZ5">1XZ5</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XZ7">1XZ7</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XZU">1XZU</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1XZV">1XZV</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y09">1Y09</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y0A">1Y0A</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y0C">1Y0C</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y0D">1Y0D</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y0T">1Y0T</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y0W">1Y0W</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y22">1Y22</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y2Z">1Y2Z</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y31">1Y31</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y35">1Y35</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y45">1Y45</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y46">1Y46</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y4B">1Y4B</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y4F">1Y4F</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y4G">1Y4G</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y4P">1Y4P</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y4Q">1Y4Q</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y4R">1Y4R</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y4V">1Y4V</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y5F">1Y5F</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y5J">1Y5J</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y5K">1Y5K</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y7C">1Y7C</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y7D">1Y7D</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y7G">1Y7G</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y7Z">1Y7Z</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y83">1Y83</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y85">1Y85</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1Y8W">1Y8W</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YDZ">1YDZ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YE0">1YE0</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YE1">1YE1</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YE2">1YE2</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YEN">1YEN</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YEO">1YEO</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YEQ">1YEQ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YEU">1YEU</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YEV">1YEV</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YFF">1YFF</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YG5">1YG5</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YGD">1YGD</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YGF">1YGF</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YH9">1YH9</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YHE">1YHE</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YHR">1YHR</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YIE">1YIE</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YIH">1YIH</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YVQ">1YVQ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YVT">1YVT</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1YZI">1YZI</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2D5Z">2D5Z</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2D60">2D60</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2DN1">2DN1</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2DN2">2DN2</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2DN3">2DN3</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2DXM">2DXM</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2H35">2H35</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2HBC">2HBC</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2HBD">2HBD</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2HBE">2HBE</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2HBF">2HBF</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2HBS">2HBS</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2HCO">2HCO</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2HHD">2HHD</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2HHE">2HHE</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2M6Z">2M6Z</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2W6V">2W6V</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2W72">2W72</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2YRS">2YRS</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3B75">3B75</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3D17">3D17</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3D7O">3D7O</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3DUT">3DUT</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3HXN">3HXN</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3IC0">3IC0</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3IC2">3IC2</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3KMF">3KMF</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3NL7">3NL7</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3NMM">3NMM</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3ODQ">3ODQ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3ONZ">3ONZ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3OO4">3OO4</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3OO5">3OO5</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3P5Q">3P5Q</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3QJB">3QJB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3QJC">3QJC</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3QJD">3QJD</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3QJE">3QJE</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3R5I">3R5I</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3S65">3S65</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3S66">3S66</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3SZK">3SZK</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3W4U">3W4U</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3WCP">3WCP</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3WHM">3WHM</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4FC3">4FC3</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4HHB">4HHB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4IJ2">4IJ2</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4L7Y">4L7Y</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4M4A">4M4A</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4M4B">4M4B</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4MQC">4MQC</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4MQG">4MQG</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4MQH">4MQH</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4MQI">4MQI</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4N7N">4N7N</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4N7O">4N7O</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4N7P">4N7P</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4N8T">4N8T</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4NI0">4NI0</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4NI1">4NI1</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4ROL">4ROL</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4ROM">4ROM</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4WJG">4WJG</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4X0L">4X0L</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4XS0">4XS0</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5E29">5E29</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5E6E">5E6E</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5EE4">5EE4</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5HU6">5HU6</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5JDO">5JDO</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5KDQ">5KDQ</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/5E83">5E83</a></span></p></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd">Identifiers</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/4827">HBB</a></span>, CD113t-C, beta-globin, hemoglobin subunit beta, ECYT6</td></tr><tr><th scope="row" style="background-color:#c3fdb8">External IDs</th><td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/141900">141900</a>; <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:5474850">5474850</a>; <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=68066">68066</a>; <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=HBB">HBB</a>; <a href="/wiki/Orthologous_MAtrix" title="Orthologous MAtrix">OMA</a>:<a rel="nofollow" class="external text" href="https://omabrowser.org/oma/vps/ENSG00000244734">HBB - orthologs</a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_human_chromosome_11.svg" class="mw-file-description" title="Chromosome 11 (human)"><img alt="Chromosome 11 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/300px-Ideogram_human_chromosome_11.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/450px-Ideogram_human_chromosome_11.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/600px-Ideogram_human_chromosome_11.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Chromosome_11_(human)" class="mw-redirect" title="Chromosome 11 (human)">Chromosome 11 (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Human_chromosome_11_ideogram.svg" class="mw-file-description" title="Chromosome 11 (human)"><img alt="Chromosome 11 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/300px-Human_chromosome_11_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/450px-Human_chromosome_11_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/600px-Human_chromosome_11_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: 5.9820343113576px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for HBB"><img alt="Genomic location for HBB" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 12px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for HBB"><img alt="Genomic location for HBB" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">11p15.4</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">5,225,464 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">5,229,395 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_house_mouse_chromosome_7.svg" class="mw-file-description" title="Chromosome 7 (mouse)"><img alt="Chromosome 7 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png" decoding="async" width="260" height="111" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/390px-Ideogram_house_mouse_chromosome_7.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/520px-Ideogram_house_mouse_chromosome_7.svg.png 2x" data-file-width="470" data-file-height="200" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks">Chromosome 7 (mouse)<sup id="cite_ref-refGRCm38Ensembl_2-0" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Ideogram_of_house_mouse_chromosome_7.svg" class="mw-file-description" title="Chromosome 7 (mouse)"><img alt="Chromosome 7 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/300px-Ideogram_of_house_mouse_chromosome_7.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/450px-Ideogram_of_house_mouse_chromosome_7.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Ideogram_of_house_mouse_chromosome_7.svg/600px-Ideogram_of_house_mouse_chromosome_7.svg.png 2x" data-file-width="1200" data-file-height="231" /></a></span><div style="position: absolute; left: 203.83708210741px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for HBB"><img alt="Genomic location for HBB" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 209.8px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for HBB"><img alt="Genomic location for HBB" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">7 E3|7</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">103,461,731 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-1" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">103,463,203 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-2" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_expression" title="Gene expression">RNA expression</a> pattern</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="https://www.bgee.org/">Bgee</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th><b><a href="/wiki/Human_genome" title="Human genome">Human</a></b></th><th><b><a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a> (ortholog)</b></th></tr><tr><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000244734">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">trabecular bone</li><br /><li style="line-height: 137%;">vena cava</li><br /><li style="line-height: 137%;">periodontal fiber</li><br /><li style="line-height: 137%;">monocyte</li><br /><li style="line-height: 137%;">bone marrow</li><br /><li style="line-height: 137%;">triceps brachii muscle</li><br /><li style="line-height: 137%;">Skeletal muscle tissue of biceps brachii</li><br /><li style="line-height: 137%;">bone marrow cells</li><br /><li style="line-height: 137%;">glutes</li><br /><li style="line-height: 137%;">blood</li></ul></div></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSMUSG00000073940">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">bone marrow</li><br /><li style="line-height: 137%;">spleen</li><br /><li style="line-height: 137%;">neural tube</li><br /><li style="line-height: 137%;">heart</li><br /><li style="line-height: 137%;">lung</li><br /><li style="line-height: 137%;">ganglionic eminence</li><br /><li style="line-height: 137%;">ventricular zone</li><br /><li style="line-height: 137%;">mesencephalon</li><br /><li style="line-height: 137%;">esophagus</li><br /><li style="line-height: 137%;">zone of skin</li></ul></div></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000244734">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:#eee">n/a</td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_ontology" class="mw-redirect" title="Gene ontology">Gene ontology</a></th></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Molecular function</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005506">iron ion binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0019825">oxygen binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005344">oxygen carrier activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0004601">peroxidase activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046872">metal ion binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030492">hemoglobin binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005515">protein binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0020037">heme binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031720">haptoglobin binding</a></li></ul> </div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Cellular component</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005829">cytosol</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071682">endocytic vesicle lumen</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0072562">blood microparticle</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005576">extracellular region</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005833">hemoglobin complex</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0070062">extracellular exosome</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031838">haptoglobin-hemoglobin complex</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1904724">tertiary granule lumen</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1904813">ficolin-1-rich granule lumen</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005615">extracellular space</a></li></ul> </div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Biological process</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010942">positive regulation of cell death</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0051291">protein heterooligomerization</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030185">nitric oxide transport</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045429">positive regulation of nitric oxide biosynthetic process</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0015671">oxygen transport</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007596">blood coagulation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006898">receptor-mediated endocytosis</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008217">regulation of blood pressure</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0015701">bicarbonate transport</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042744">hydrogen peroxide catabolic process</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0070527">platelet aggregation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042542">response to hydrogen peroxide</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0070293">renal absorption</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0098869">cellular oxidant detoxification</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043312">neutrophil degranulation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006810">transport</a></li></ul> </div></td></tr><tr><td colspan="4" style="background-color:#eee;text-align:center">Sources:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:#c3fdb8">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=3043&rn=1">3043</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=101488143&rn=1">101488143</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000244734;db=core">ENSG00000244734</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000073940;db=core">ENSMUSG00000073940</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P68871">P68871</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P02088">P02088</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (mRNA)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_000518">NM_000518</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_008220">NM_008220</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (protein)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_000509">NP_000509</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_032246">NP_032246</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001188320">NP_001188320</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001265090">NP_001265090</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Location (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chr11:5225464-5229395">Chr 11: 5.23 – 5.23 Mb</a></span></td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm0&position=chr7:103461731-103463203">Chr 7: 103.46 – 103.46 Mb</a></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> search</th><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q14905542" class="extiw" title="d:Q14905542">View/Edit Human</a></td><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q18323639" class="extiw" title="d:Q18323639">View/Edit Mouse</a></td></tr></tbody></table></td></tr></tbody></table> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:HBB_location.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/07/HBB_location.png/220px-HBB_location.png" decoding="async" width="220" height="113" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/07/HBB_location.png/330px-HBB_location.png 1.5x, //upload.wikimedia.org/wikipedia/commons/0/07/HBB_location.png 2x" data-file-width="365" data-file-height="188" /></a><figcaption>In human, the HBB gene is located on <a href="/wiki/Chromosome_11_(human)" class="mw-redirect" title="Chromosome 11 (human)">chromosome 11</a> at position p15.5.</figcaption></figure> <p><b>Hemoglobin subunit beta</b> (<b>beta globin</b>, <b>β-globin</b>, <b>haemoglobin beta</b>, <b>hemoglobin beta</b>) is a <a href="/wiki/Globin" title="Globin">globin</a> <a href="/wiki/Protein" title="Protein">protein</a>, coded for by the <i>HBB</i> gene, which along with alpha globin (<a href="/wiki/HBA1" class="mw-redirect" title="HBA1">HBA</a>), makes up the most common form of <a href="/wiki/Haemoglobin" class="mw-redirect" title="Haemoglobin">haemoglobin</a> in adult humans, <a href="/wiki/Hemoglobin_A" title="Hemoglobin A">hemoglobin A</a> (HbA).<sup id="cite_ref-entrez_5-0" class="reference"><a href="#cite_note-entrez-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> It is 147 amino acids long and has a molecular weight of 15,867 <a href="/wiki/Dalton_(unit)" title="Dalton (unit)">Da</a>. Normal adult human HbA is a <a href="/wiki/Tetrameric_protein" title="Tetrameric protein">heterotetramer</a> consisting of two alpha chains and two beta chains. </p><p>β-globin is encoded by the <i>HBB</i> gene on <a href="/wiki/Chromosome_11_(human)" class="mw-redirect" title="Chromosome 11 (human)">human chromosome 11</a>. Mutations in the gene produce several variants of the proteins which are implicated with genetic disorders such as <a href="/wiki/Sickle-cell_disease" class="mw-redirect" title="Sickle-cell disease">sickle-cell disease</a> and <a href="/wiki/Beta_thalassemia" title="Beta thalassemia">beta thalassemia</a>, as well as beneficial traits such as <a href="/wiki/Genetic_resistance_to_malaria" class="mw-redirect" title="Genetic resistance to malaria">genetic resistance to malaria</a>.<sup id="cite_ref-sabeti_6-0" class="reference"><a href="#cite_note-sabeti-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-kwiat_7-0" class="reference"><a href="#cite_note-kwiat-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> At least 50 disease-causing mutations in this gene have been discovered.<sup id="cite_ref-Šimčíková_2019_-_supplementary_table_S7_8-0" class="reference"><a href="#cite_note-Šimčíková_2019_-_supplementary_table_S7-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Gene_locus">Gene locus</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=1" title="Edit section: Gene locus"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Human_%CE%B2-globin_locus" title="Human β-globin locus">Human β-globin locus</a></div> <p>HBB protein is produced by the gene <i>HBB</i> which is located in the multigene locus of <a href="/wiki/Human_%CE%B2-globin_locus" title="Human β-globin locus">β-globin locus</a> on <a href="/wiki/Chromosome_11_(human)" class="mw-redirect" title="Chromosome 11 (human)">chromosome 11</a>, specifically on the short arm position 15.4. <a href="/wiki/Gene_expression" title="Gene expression">Expression</a> of beta globin and the neighbouring globins in the β-globin locus is controlled by single <a href="/wiki/Locus_control_region" title="Locus control region">locus control region</a> (LCR), the most important regulatory element in the locus located upstream of the globin genes.<sup id="cite_ref-pmid11895428_9-0" class="reference"><a href="#cite_note-pmid11895428-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> The normal allelic variant is 1600 <a href="/wiki/Base_pair" title="Base pair">base pairs</a> (bp) long and contains three <a href="/wiki/Exon" title="Exon">exons</a>. The order of the genes in the beta-globin cluster is 5' - <a href="/wiki/HBE1" title="HBE1">epsilon</a> – <a href="/wiki/HBG2" title="HBG2">gamma-G</a> – <a href="/wiki/HBG1" title="HBG1">gamma-A</a> – <a href="/wiki/HBD" title="HBD">delta</a> – beta - 3'.<sup id="cite_ref-entrez_5-1" class="reference"><a href="#cite_note-entrez-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Interactions">Interactions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=2" title="Edit section: Interactions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>HBB <a href="/wiki/Protein-protein_interaction" class="mw-redirect" title="Protein-protein interaction">interacts</a> with <a href="/w/index.php?title=Haemoglobin,_alpha_1&action=edit&redlink=1" class="new" title="Haemoglobin, alpha 1 (page does not exist)">Haemoglobin, alpha 1</a> (HBA1) to form haemoglobin A, the major haemoglobin in adult humans.<sup id="cite_ref-pmid16169070_10-0" class="reference"><a href="#cite_note-pmid16169070-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid6644819_11-0" class="reference"><a href="#cite_note-pmid6644819-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> The interaction is two-fold. First, one HBB and one HBA1 combine, non-covalently, to form a dimer. Secondly, two dimers combine to form the four-chain tetramer, and this becomes the functional haemoglobin.<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Associated_genetic_disorders">Associated genetic disorders</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=3" title="Edit section: Associated genetic disorders"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Beta_thalassemia">Beta thalassemia</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=4" title="Edit section: Beta thalassemia"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Beta_thalassemia" title="Beta thalassemia">Beta thalassemia</a> is an inherited genetic mutation in one (Beta thalassemia minor) or both (Beta thalassemia major) of the Beta globin alleles on chromosome 11. The mutant alleles are subdivided into two groups: β0, in which no functional β-globin is made, and β+, in which a small amount of normal β-globin protein is produced. Beta thalassemia minor occurs when an individual inherits one normal Beta allele and one abnormal Beta allele (either β0, or β+). Beta thalassemia minor results in a mild microcytic anemia that is often asymptomatic or may cause fatigue and or pale skin. Beta thalassemia major occurs when a person inherits two abnormal alleles. This can be either two β+ alleles, two β0 alleles, or one of each. Beta thalassemia major is a severe medical condition. A severe anemia is seen starting at 6 months of age. Without medical treatment death often occurs before age 12. <sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> Beta thalassemia major can be treated by lifelong <a href="/wiki/Blood_transfusions" class="mw-redirect" title="Blood transfusions">blood transfusions</a> or <a href="/wiki/Bone_marrow_transplantation" class="mw-redirect" title="Bone marrow transplantation">bone marrow transplantation</a>.<sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p><p>According to a recent study, the stop gain mutation <b>Gln40stop</b> in <i><b>HBB</b></i> gene is a common cause of <a href="/wiki/Autosomal_recessive" class="mw-redirect" title="Autosomal recessive">autosomal recessive</a> <a href="/wiki/Beta_thalassemia" title="Beta thalassemia">Beta- thalassemia</a> in <a href="/wiki/Sardinian_people" title="Sardinian people">Sardinian people</a> (almost exclusive in Sardinia). Carriers of this mutation show an enhanced red blood cell count. As a curiosity, the same mutation was also associated to a decrease in serum <a href="/wiki/LDL" class="mw-redirect" title="LDL">LDL</a> levels in carriers, so the authors suggest that is due to the need of <a href="/wiki/Cholesterol" title="Cholesterol">cholesterol</a> to regenerate cell membranes.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Sickle_cell_disease">Sickle cell disease</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=5" title="Edit section: Sickle cell disease"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>More than a thousand naturally occurring <i>HBB</i> variants have been discovered. The most common is HbS, which causes <a href="/wiki/Sickle_cell_disease" title="Sickle cell disease">sickle cell disease</a>. HbS is produced by a <a href="/wiki/Point_mutation" title="Point mutation">point mutation</a> in <i>HBB</i> in which the <a href="/wiki/Codon" class="mw-redirect" title="Codon">codon</a> GAG is replaced by GTG. This results in the replacement of hydrophilic amino acid <a href="/wiki/Glutamic_acid" title="Glutamic acid">glutamic acid</a> with the hydrophobic amino acid <a href="/wiki/Valine" title="Valine">valine</a> at the seventh position (β6Glu→Val). This substitution creates a hydrophobic spot on the outside of the protein that sticks to the hydrophobic region of an adjacent hemoglobin molecule's beta chain. This further causes clumping of HbS molecules into rigid fibers, causing "sickling" of the entire <a href="/wiki/Red_blood_cell" title="Red blood cell">red blood cells</a> in the <a href="/wiki/Zygosity" title="Zygosity">homozygous</a> (<i>HbS/HbS</i>) condition.<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> The homozygous allele has become one of the deadliest genetic factors,<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> whereas people heterozygous for the mutant allele (<i>HbS/HbA</i>) are resistant to <a href="/wiki/Malaria" title="Malaria">malaria</a> and develop minimal effects of the anaemia.<sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Haemoglobin_C">Haemoglobin C</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=6" title="Edit section: Haemoglobin C"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Sickle cell disease is closely related to another mutant haemoglobin called <a href="/wiki/Haemoglobin_C" class="mw-redirect" title="Haemoglobin C">haemoglobin C</a> (HbC), because they can be inherited together.<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> HbC mutation is at the same position in HbS, but glutamic acid is replaced by <a href="/wiki/Lysine" title="Lysine">lysine</a> (β6Glu→Lys). The mutation is particularly prevalent in West African populations. HbC provides near full protection against <i><a href="/wiki/Plasmodium_falciparum" title="Plasmodium falciparum">Plasmodium falciparum</a> </i>in homozygous (CC) individuals and intermediate protection in heterozygous (AC) individuals.<sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> This indicates that HbC has stronger influence than HbS, and is predicted to replace HbS in malaria-endemic regions.<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Haemoglobin_E">Haemoglobin E</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=7" title="Edit section: Haemoglobin E"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Another point mutation in HBB, in which glutamic acid is replaced with lysine at position 26 (β26Glu→Lys), leads to the formation of <a href="/wiki/Haemoglobin_E" class="mw-redirect" title="Haemoglobin E">haemoglobin E</a> (HbE).<sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> HbE has a very unstable α- and β-globin association. Even though the unstable protein itself has mild effect, inherited with HbS and thalassemia traits, it turns into a life-threatening form of β-thalassemia. The mutation is of relatively recent origin suggesting that it resulted from selective pressure against severe falciparum malaria, as heterozygous allele prevents the development of malaria.<sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Human_evolution">Human evolution</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=8" title="Edit section: Human evolution"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Malaria due to <i>Plasmodium falciparum</i> is a major selective factor in <a href="/wiki/Human_evolution" title="Human evolution">human evolution</a>.<sup id="cite_ref-kwiat_7-1" class="reference"><a href="#cite_note-kwiat-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-25" class="reference"><a href="#cite_note-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> It has influenced mutations in <i>HBB</i> in various degrees resulting in the existence of numerous HBB variants. Some of these mutations are not directly lethal and instead confer resistance to malaria, particularly in Africa where malaria is epidemic.<sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup> People of African descent have evolved to have higher rates of the mutant HBB because the heterozygous individuals have a misshaped red blood cell that prevent attacks from malarial parasites. Thus, HBB mutants are the sources of positive selection in these regions and are important for their long-term survival.<sup id="cite_ref-sabeti_6-1" class="reference"><a href="#cite_note-sabeti-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> Such selection markers are important for tracing human ancestry and <a href="/wiki/Recent_African_origin_of_modern_humans" title="Recent African origin of modern humans">diversification from Africa</a>.<sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=9" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Hemoglobin_subunit_alpha" title="Hemoglobin subunit alpha">Hemoglobin subunit alpha</a></li> <li><a href="/wiki/Human_%CE%B2-globin_locus" title="Human β-globin locus">Human β-globin locus</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=10" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output 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duplication/insertion in exon II of the beta globin gene causing beta0-thalassemia"</a>. <i>Haematologica</i>. <b>92</b> (3): 423–4. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.3324%2Fhaematol.10785">10.3324/haematol.10785</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17339197">17339197</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Haematologica&rft.atitle=A+65+bp+duplication%2Finsertion+in+exon+II+of+the+beta+globin+gene+causing+beta0-thalassemia.&rft.volume=92&rft.issue=3&rft.pages=423-4&rft.date=2007&rft_id=info%3Adoi%2F10.3324%2Fhaematol.10785&rft_id=info%3Apmid%2F17339197&rft.aulast=Frischknecht&rft.aufirst=H&rft.au=Dutly%2C+F&rft_id=https%3A%2F%2Fdoi.org%2F10.3324%252Fhaematol.10785&rfr_id=info%3Asid%2Fen.wikipedia.org%3AHemoglobin+subunit+beta" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Hemoglobin_subunit_beta&action=edit&section=12" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>Overview of all the structural information available in the <a 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srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/34/PDB_1a00_EBI.jpg/270px-PDB_1a00_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/34/PDB_1a00_EBI.jpg/360px-PDB_1a00_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1a00</b>: HEMOGLOBIN (VAL BETA1 MET, TRP BETA37 TYR) MUTANT</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1a01_EBI.jpg" class="mw-file-description" title="1a01: HEMOGLOBIN (VAL BETA1 MET, TRP BETA37 ALA) MUTANT"><img alt="1a01: HEMOGLOBIN (VAL BETA1 MET, TRP BETA37 ALA) MUTANT" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/ca/PDB_1a01_EBI.jpg/180px-PDB_1a01_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/ca/PDB_1a01_EBI.jpg/270px-PDB_1a01_EBI.jpg 1.5x, 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srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/ae/PDB_1abw_EBI.jpg/270px-PDB_1abw_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/ae/PDB_1abw_EBI.jpg/360px-PDB_1abw_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1abw</b>: DEOXY RHB1.1 (RECOMBINANT HEMOGLOBIN)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1aby_EBI.jpg" class="mw-file-description" title="1aby: CYANOMET RHB1.1 (RECOMBINANT HEMOGLOBIN)"><img alt="1aby: CYANOMET RHB1.1 (RECOMBINANT HEMOGLOBIN)" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_1aby_EBI.jpg/180px-PDB_1aby_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_1aby_EBI.jpg/270px-PDB_1aby_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_1aby_EBI.jpg/360px-PDB_1aby_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1aby</b>: CYANOMET RHB1.1 (RECOMBINANT HEMOGLOBIN)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1aj9_EBI.jpg" class="mw-file-description" title="1aj9: R-STATE HUMAN CARBONMONOXYHEMOGLOBIN ALPHA-A53S"><img alt="1aj9: R-STATE HUMAN CARBONMONOXYHEMOGLOBIN ALPHA-A53S" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/PDB_1aj9_EBI.jpg/180px-PDB_1aj9_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/PDB_1aj9_EBI.jpg/270px-PDB_1aj9_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f6/PDB_1aj9_EBI.jpg/360px-PDB_1aj9_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1aj9</b>: R-STATE HUMAN CARBONMONOXYHEMOGLOBIN ALPHA-A53S</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1b86_EBI.jpg" class="mw-file-description" title="1b86: HUMAN DEOXYHAEMOGLOBIN-2,3-DIPHOSPHOGLYCERATE COMPLEX"><img alt="1b86: HUMAN DEOXYHAEMOGLOBIN-2,3-DIPHOSPHOGLYCERATE COMPLEX" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1b86_EBI.jpg/180px-PDB_1b86_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1b86_EBI.jpg/270px-PDB_1b86_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1b86_EBI.jpg/360px-PDB_1b86_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1b86</b>: HUMAN DEOXYHAEMOGLOBIN-2,3-DIPHOSPHOGLYCERATE COMPLEX</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1bab_EBI.jpg" class="mw-file-description" title="1bab: HEMOGLOBIN THIONVILLE: AN ALPHA-CHAIN VARIANT WITH A SUBSTITUTION OF A GLUTAMATE FOR VALINE AT NA-1 AND HAVING AN ACETYLATED METHIONINE NH2 TERMINUS"><img alt="1bab: HEMOGLOBIN THIONVILLE: AN ALPHA-CHAIN VARIANT WITH A SUBSTITUTION OF A GLUTAMATE FOR VALINE AT NA-1 AND HAVING AN ACETYLATED METHIONINE NH2 TERMINUS" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/19/PDB_1bab_EBI.jpg/180px-PDB_1bab_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/19/PDB_1bab_EBI.jpg/270px-PDB_1bab_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/19/PDB_1bab_EBI.jpg/360px-PDB_1bab_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1bab</b>: HEMOGLOBIN THIONVILLE: AN ALPHA-CHAIN VARIANT WITH A SUBSTITUTION OF A GLUTAMATE FOR VALINE AT NA-1 AND HAVING AN ACETYLATED METHIONINE NH2 TERMINUS</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1bbb_EBI.jpg" class="mw-file-description" title="1bbb: A THIRD QUATERNARY STRUCTURE OF HUMAN HEMOGLOBIN A AT 1.7-ANGSTROMS RESOLUTION"><img alt="1bbb: A THIRD QUATERNARY STRUCTURE OF HUMAN HEMOGLOBIN A AT 1.7-ANGSTROMS RESOLUTION" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5d/PDB_1bbb_EBI.jpg/180px-PDB_1bbb_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5d/PDB_1bbb_EBI.jpg/270px-PDB_1bbb_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/5d/PDB_1bbb_EBI.jpg/360px-PDB_1bbb_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1bbb</b>: A THIRD QUATERNARY STRUCTURE OF HUMAN HEMOGLOBIN A AT 1.7-ANGSTROMS RESOLUTION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1bij_EBI.jpg" class="mw-file-description" title="1bij: CROSSLINKED, DEOXY HUMAN HEMOGLOBIN A"><img alt="1bij: CROSSLINKED, DEOXY HUMAN HEMOGLOBIN A" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/PDB_1bij_EBI.jpg/180px-PDB_1bij_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/PDB_1bij_EBI.jpg/270px-PDB_1bij_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e7/PDB_1bij_EBI.jpg/360px-PDB_1bij_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1bij</b>: CROSSLINKED, DEOXY HUMAN HEMOGLOBIN A</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1buw_EBI.jpg" class="mw-file-description" title="1buw: CRYSTAL STRUCTURE OF S-NITROSO-NITROSYL HUMAN HEMOGLOBIN A"><img alt="1buw: CRYSTAL STRUCTURE OF S-NITROSO-NITROSYL HUMAN HEMOGLOBIN A" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/47/PDB_1buw_EBI.jpg/180px-PDB_1buw_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/47/PDB_1buw_EBI.jpg/270px-PDB_1buw_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/47/PDB_1buw_EBI.jpg/360px-PDB_1buw_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1buw</b>: CRYSTAL STRUCTURE OF S-NITROSO-NITROSYL HUMAN HEMOGLOBIN A</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1bz0_EBI.jpg" class="mw-file-description" title="1bz0: HEMOGLOBIN A (HUMAN, DEOXY, HIGH SALT)"><img alt="1bz0: HEMOGLOBIN A (HUMAN, DEOXY, HIGH SALT)" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6e/PDB_1bz0_EBI.jpg/180px-PDB_1bz0_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6e/PDB_1bz0_EBI.jpg/270px-PDB_1bz0_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6e/PDB_1bz0_EBI.jpg/360px-PDB_1bz0_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1bz0</b>: HEMOGLOBIN A (HUMAN, DEOXY, HIGH SALT)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1bz1_EBI.jpg" class="mw-file-description" title="1bz1: HEMOGLOBIN (ALPHA + MET) VARIANT"><img alt="1bz1: HEMOGLOBIN (ALPHA + MET) VARIANT" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1bz1_EBI.jpg/180px-PDB_1bz1_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1bz1_EBI.jpg/270px-PDB_1bz1_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1bz1_EBI.jpg/360px-PDB_1bz1_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1bz1</b>: HEMOGLOBIN (ALPHA + MET) VARIANT</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1bzz_EBI.jpg" class="mw-file-description" title="1bzz: HEMOGLOBIN (ALPHA V1M) MUTANT"><img alt="1bzz: HEMOGLOBIN (ALPHA V1M) MUTANT" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8c/PDB_1bzz_EBI.jpg/180px-PDB_1bzz_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8c/PDB_1bzz_EBI.jpg/270px-PDB_1bzz_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8c/PDB_1bzz_EBI.jpg/360px-PDB_1bzz_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1bzz</b>: HEMOGLOBIN (ALPHA V1M) MUTANT</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1c7b_EBI.jpg" class="mw-file-description" title="1c7b: DEOXY RHB1.0 (RECOMBINANT HEMOGLOBIN)"><img alt="1c7b: DEOXY RHB1.0 (RECOMBINANT HEMOGLOBIN)" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/97/PDB_1c7b_EBI.jpg/180px-PDB_1c7b_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/97/PDB_1c7b_EBI.jpg/270px-PDB_1c7b_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/97/PDB_1c7b_EBI.jpg/360px-PDB_1c7b_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1c7b</b>: DEOXY RHB1.0 (RECOMBINANT HEMOGLOBIN)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1c7c_EBI.jpg" class="mw-file-description" title="1c7c: DEOXY RHB1.1 (RECOMBINANT HEMOGLOBIN)"><img alt="1c7c: DEOXY RHB1.1 (RECOMBINANT HEMOGLOBIN)" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1c7c_EBI.jpg/180px-PDB_1c7c_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1c7c_EBI.jpg/270px-PDB_1c7c_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1c7c_EBI.jpg/360px-PDB_1c7c_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1c7c</b>: DEOXY RHB1.1 (RECOMBINANT HEMOGLOBIN)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1c7d_EBI.jpg" class="mw-file-description" title="1c7d: DEOXY RHB1.2 (RECOMBINANT HEMOGLOBIN)"><img alt="1c7d: DEOXY RHB1.2 (RECOMBINANT HEMOGLOBIN)" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c6/PDB_1c7d_EBI.jpg/180px-PDB_1c7d_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c6/PDB_1c7d_EBI.jpg/270px-PDB_1c7d_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c6/PDB_1c7d_EBI.jpg/360px-PDB_1c7d_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1c7d</b>: DEOXY RHB1.2 (RECOMBINANT HEMOGLOBIN)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1cbl_EBI.jpg" class="mw-file-description" title="1cbl: THE 1.9 ANGSTROM STRUCTURE OF DEOXY-BETA4 HEMOGLOBIN: ANALYSIS OF THE PARTITIONING OF QUATERNARY-ASSOCIATED AND LIGAND-INDUCED CHANGES IN TERTIARY STRUCTURE"><img alt="1cbl: THE 1.9 ANGSTROM STRUCTURE OF DEOXY-BETA4 HEMOGLOBIN: ANALYSIS OF THE PARTITIONING OF QUATERNARY-ASSOCIATED AND LIGAND-INDUCED CHANGES IN TERTIARY STRUCTURE" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/PDB_1cbl_EBI.jpg/180px-PDB_1cbl_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/PDB_1cbl_EBI.jpg/270px-PDB_1cbl_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/7e/PDB_1cbl_EBI.jpg/360px-PDB_1cbl_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1cbl</b>: THE 1.9 ANGSTROM STRUCTURE OF DEOXY-BETA4 HEMOGLOBIN: ANALYSIS OF THE PARTITIONING OF QUATERNARY-ASSOCIATED AND LIGAND-INDUCED CHANGES IN TERTIARY STRUCTURE</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1cbm_EBI.jpg" class="mw-file-description" title="1cbm: THE 1.8 ANGSTROM STRUCTURE OF CARBONMONOXY-BETA4 HEMOGLOBIN: ANALYSIS OF A HOMOTETRAMER WITH THE R QUATERNARY STRUCTURE OF LIGANDED ALPHA2BETA2 HEMOGLOBIN"><img alt="1cbm: THE 1.8 ANGSTROM STRUCTURE OF CARBONMONOXY-BETA4 HEMOGLOBIN: ANALYSIS OF A HOMOTETRAMER WITH THE R QUATERNARY STRUCTURE OF LIGANDED ALPHA2BETA2 HEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6e/PDB_1cbm_EBI.jpg/180px-PDB_1cbm_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6e/PDB_1cbm_EBI.jpg/270px-PDB_1cbm_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6e/PDB_1cbm_EBI.jpg/360px-PDB_1cbm_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1cbm</b>: THE 1.8 ANGSTROM STRUCTURE OF CARBONMONOXY-BETA4 HEMOGLOBIN: ANALYSIS OF A HOMOTETRAMER WITH THE R QUATERNARY STRUCTURE OF LIGANDED ALPHA2BETA2 HEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1cls_EBI.jpg" class="mw-file-description" title="1cls: CROSS-LINKED HUMAN HEMOGLOBIN DEOXY"><img alt="1cls: CROSS-LINKED HUMAN HEMOGLOBIN DEOXY" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/PDB_1cls_EBI.jpg/180px-PDB_1cls_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/PDB_1cls_EBI.jpg/270px-PDB_1cls_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/7e/PDB_1cls_EBI.jpg/360px-PDB_1cls_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1cls</b>: CROSS-LINKED HUMAN HEMOGLOBIN DEOXY</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1cmy_EBI.jpg" class="mw-file-description" title="1cmy: THE MUTATION BETA99 ASP-TYR STABILIZES Y-A NEW, COMPOSITE QUATERNARY STATE OF HUMAN HEMOGLOBIN"><img alt="1cmy: THE MUTATION BETA99 ASP-TYR STABILIZES Y-A NEW, COMPOSITE QUATERNARY STATE OF HUMAN HEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/30/PDB_1cmy_EBI.jpg/180px-PDB_1cmy_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/30/PDB_1cmy_EBI.jpg/270px-PDB_1cmy_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/30/PDB_1cmy_EBI.jpg/360px-PDB_1cmy_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1cmy</b>: THE MUTATION BETA99 ASP-TYR STABILIZES Y-A NEW, COMPOSITE QUATERNARY STATE OF HUMAN HEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1coh_EBI.jpg" class="mw-file-description" title="1coh: STRUCTURE OF HAEMOGLOBIN IN THE DEOXY QUATERNARY STATE WITH LIGAND BOUND AT THE ALPHA HAEMS"><img alt="1coh: STRUCTURE OF HAEMOGLOBIN IN THE DEOXY QUATERNARY STATE WITH LIGAND BOUND AT THE ALPHA HAEMS" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/51/PDB_1coh_EBI.jpg/180px-PDB_1coh_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/51/PDB_1coh_EBI.jpg/270px-PDB_1coh_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/51/PDB_1coh_EBI.jpg/360px-PDB_1coh_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1coh</b>: STRUCTURE OF HAEMOGLOBIN IN THE DEOXY QUATERNARY STATE WITH LIGAND BOUND AT THE ALPHA HAEMS</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1dke_EBI.jpg" class="mw-file-description" title="1dke: NI BETA HEME HUMAN HEMOGLOBIN"><img alt="1dke: NI BETA HEME HUMAN HEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/da/PDB_1dke_EBI.jpg/180px-PDB_1dke_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/da/PDB_1dke_EBI.jpg/270px-PDB_1dke_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/da/PDB_1dke_EBI.jpg/360px-PDB_1dke_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1dke</b>: NI BETA HEME HUMAN HEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1dxt_EBI.jpg" class="mw-file-description" title="1dxt: HIGH-RESOLUTION X-RAY STUDY OF DEOXY RECOMBINANT HUMAN HEMOGLOBINS SYNTHESIZED FROM BETA-GLOBINS HAVING MUTATED AMINO TERMINI"><img alt="1dxt: HIGH-RESOLUTION X-RAY STUDY OF DEOXY RECOMBINANT HUMAN HEMOGLOBINS SYNTHESIZED FROM BETA-GLOBINS HAVING MUTATED AMINO TERMINI" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/da/PDB_1dxt_EBI.jpg/180px-PDB_1dxt_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/da/PDB_1dxt_EBI.jpg/270px-PDB_1dxt_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/da/PDB_1dxt_EBI.jpg/360px-PDB_1dxt_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1dxt</b>: HIGH-RESOLUTION X-RAY STUDY OF DEOXY RECOMBINANT HUMAN HEMOGLOBINS SYNTHESIZED FROM BETA-GLOBINS HAVING MUTATED AMINO TERMINI</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1dxu_EBI.jpg" class="mw-file-description" title="1dxu: HIGH-RESOLUTION X-RAY STUDY OF DEOXY RECOMBINANT 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210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1fn3_EBI.jpg" class="mw-file-description" title="1fn3: CRYSTAL STRUCTURE OF NICKEL RECONSTITUTED HEMOGLOBIN-A CASE FOR PERMANENT, T-STATE HEMOGLOBIN"><img alt="1fn3: CRYSTAL STRUCTURE OF NICKEL RECONSTITUTED HEMOGLOBIN-A CASE FOR PERMANENT, T-STATE HEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8d/PDB_1fn3_EBI.jpg/180px-PDB_1fn3_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8d/PDB_1fn3_EBI.jpg/270px-PDB_1fn3_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8d/PDB_1fn3_EBI.jpg/360px-PDB_1fn3_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1fn3</b>: CRYSTAL STRUCTURE OF NICKEL RECONSTITUTED HEMOGLOBIN-A CASE FOR PERMANENT, T-STATE HEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1g9v_EBI.jpg" class="mw-file-description" title="1g9v: HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXY HEMOGLOBIN COMPLEXED WITH A POTENT ALLOSTERIC EFFECTOR"><img alt="1g9v: HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXY HEMOGLOBIN COMPLEXED WITH A POTENT ALLOSTERIC EFFECTOR" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/PDB_1g9v_EBI.jpg/180px-PDB_1g9v_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/PDB_1g9v_EBI.jpg/270px-PDB_1g9v_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3e/PDB_1g9v_EBI.jpg/360px-PDB_1g9v_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1g9v</b>: HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXY HEMOGLOBIN COMPLEXED WITH A POTENT ALLOSTERIC EFFECTOR</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1gbu_EBI.jpg" class="mw-file-description" title="1gbu: DEOXY (BETA-(C93A,C112G)) HUMAN HEMOGLOBIN"><img alt="1gbu: DEOXY (BETA-(C93A,C112G)) HUMAN HEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/87/PDB_1gbu_EBI.jpg/180px-PDB_1gbu_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/87/PDB_1gbu_EBI.jpg/270px-PDB_1gbu_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/87/PDB_1gbu_EBI.jpg/360px-PDB_1gbu_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1gbu</b>: DEOXY (BETA-(C93A,C112G)) HUMAN HEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1gbv_EBI.jpg" class="mw-file-description" title="1gbv: (ALPHA-OXY, BETA-(C112G)DEOXY) T-STATE HUMAN HEMOGLOBIN"><img alt="1gbv: (ALPHA-OXY, BETA-(C112G)DEOXY) T-STATE HUMAN HEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/92/PDB_1gbv_EBI.jpg/180px-PDB_1gbv_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/92/PDB_1gbv_EBI.jpg/270px-PDB_1gbv_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/92/PDB_1gbv_EBI.jpg/360px-PDB_1gbv_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1gbv</b>: (ALPHA-OXY, BETA-(C112G)DEOXY) T-STATE HUMAN HEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1gli_EBI.jpg" class="mw-file-description" title="1gli: DEOXYHEMOGLOBIN T38W (ALPHA CHAINS), V1G (ALPHA AND BETA CHAINS)"><img alt="1gli: DEOXYHEMOGLOBIN T38W (ALPHA CHAINS), V1G (ALPHA AND BETA CHAINS)" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/53/PDB_1gli_EBI.jpg/180px-PDB_1gli_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/53/PDB_1gli_EBI.jpg/270px-PDB_1gli_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/53/PDB_1gli_EBI.jpg/360px-PDB_1gli_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1gli</b>: DEOXYHEMOGLOBIN T38W (ALPHA CHAINS), V1G (ALPHA AND BETA CHAINS)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1gzx_EBI.jpg" class="mw-file-description" title="1gzx: OXY T STATE HAEMOGLOBIN: OXYGEN BOUND AT ALL FOUR HAEMS"><img alt="1gzx: OXY T STATE HAEMOGLOBIN: OXYGEN BOUND AT ALL FOUR HAEMS" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bb/PDB_1gzx_EBI.jpg/180px-PDB_1gzx_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bb/PDB_1gzx_EBI.jpg/270px-PDB_1gzx_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bb/PDB_1gzx_EBI.jpg/360px-PDB_1gzx_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1gzx</b>: OXY T STATE HAEMOGLOBIN: OXYGEN BOUND AT ALL FOUR HAEMS</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1hab_EBI.jpg" class="mw-file-description" title="1hab: CROSSLINKED HAEMOGLOBIN"><img alt="1hab: CROSSLINKED HAEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1hab_EBI.jpg/180px-PDB_1hab_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1hab_EBI.jpg/270px-PDB_1hab_EBI.jpg 1.5x, 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height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1hga_EBI.jpg" class="mw-file-description" title="1hga: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN"><img alt="1hga: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/18/PDB_1hga_EBI.jpg/180px-PDB_1hga_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/18/PDB_1hga_EBI.jpg/270px-PDB_1hga_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/18/PDB_1hga_EBI.jpg/360px-PDB_1hga_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1hga</b>: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1hgb_EBI.jpg" class="mw-file-description" title="1hgb: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN"><img alt="1hgb: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/35/PDB_1hgb_EBI.jpg/180px-PDB_1hgb_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/35/PDB_1hgb_EBI.jpg/270px-PDB_1hgb_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/35/PDB_1hgb_EBI.jpg/360px-PDB_1hgb_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1hgb</b>: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1hgc_EBI.jpg" class="mw-file-description" title="1hgc: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN"><img alt="1hgc: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/9c/PDB_1hgc_EBI.jpg/180px-PDB_1hgc_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/9c/PDB_1hgc_EBI.jpg/270px-PDB_1hgc_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/9c/PDB_1hgc_EBI.jpg/360px-PDB_1hgc_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1hgc</b>: HIGH RESOLUTION CRYSTAL STRUCTURES AND COMPARISONS OF T STATE DEOXYHAEMOGLOBIN AND TWO LIGANDED T-STATE HAEMOGLOBINS: T(ALPHA-OXY)HAEMOGLOBIN AND T(MET)HAEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1hho_EBI.jpg" class="mw-file-description" title="1hho: STRUCTURE OF HUMAN OXYHAEMOGLOBIN AT 2.1 ANGSTROMS RESOLUTION"><img alt="1hho: STRUCTURE OF HUMAN OXYHAEMOGLOBIN AT 2.1 ANGSTROMS RESOLUTION" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ea/PDB_1hho_EBI.jpg/180px-PDB_1hho_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ea/PDB_1hho_EBI.jpg/270px-PDB_1hho_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ea/PDB_1hho_EBI.jpg/360px-PDB_1hho_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1hho</b>: STRUCTURE OF HUMAN OXYHAEMOGLOBIN AT 2.1 ANGSTROMS RESOLUTION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1ird_EBI.jpg" class="mw-file-description" title="1ird: Crystal Structure of Human Carbonmonoxy-Haemoglobin at 1.25 A Resolution"><img alt="1ird: Crystal Structure of Human Carbonmonoxy-Haemoglobin at 1.25 A Resolution" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/97/PDB_1ird_EBI.jpg/180px-PDB_1ird_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/97/PDB_1ird_EBI.jpg/270px-PDB_1ird_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/97/PDB_1ird_EBI.jpg/360px-PDB_1ird_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1ird</b>: Crystal Structure of Human Carbonmonoxy-Haemoglobin at 1.25 A Resolution</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1j3y_EBI.jpg" class="mw-file-description" title="1j3y: Direct observation of photolysis-induced tertiary structural changes in human hemoglobin; Crystal structure of alpha(Fe)-beta(Ni) hemoglobin (laser photolysed)"><img alt="1j3y: Direct observation of photolysis-induced tertiary structural changes in human hemoglobin; Crystal structure of alpha(Fe)-beta(Ni) hemoglobin (laser photolysed)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/PDB_1j3y_EBI.jpg/180px-PDB_1j3y_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/PDB_1j3y_EBI.jpg/270px-PDB_1j3y_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e0/PDB_1j3y_EBI.jpg/360px-PDB_1j3y_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1j3y</b>: Direct observation of photolysis-induced tertiary structural changes in human hemoglobin; Crystal structure of alpha(Fe)-beta(Ni) hemoglobin (laser photolysed)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1j3z_EBI.jpg" class="mw-file-description" title="1j3z: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Fe-CO)-beta(Ni) hemoglobin (laser unphotolysed)"><img alt="1j3z: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Fe-CO)-beta(Ni) hemoglobin (laser unphotolysed)" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/62/PDB_1j3z_EBI.jpg/180px-PDB_1j3z_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/62/PDB_1j3z_EBI.jpg/270px-PDB_1j3z_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/62/PDB_1j3z_EBI.jpg/360px-PDB_1j3z_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1j3z</b>: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Fe-CO)-beta(Ni) hemoglobin (laser unphotolysed)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1j40_EBI.jpg" class="mw-file-description" title="1j40: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe-CO) hemoglobin (laser unphotolysed)"><img alt="1j40: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe-CO) hemoglobin (laser unphotolysed)" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a3/PDB_1j40_EBI.jpg/180px-PDB_1j40_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a3/PDB_1j40_EBI.jpg/270px-PDB_1j40_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a3/PDB_1j40_EBI.jpg/360px-PDB_1j40_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1j40</b>: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe-CO) hemoglobin (laser unphotolysed)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1j41_EBI.jpg" class="mw-file-description" title="1j41: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe) hemoglobin (laser photolysed)"><img alt="1j41: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe) hemoglobin (laser photolysed)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ea/PDB_1j41_EBI.jpg/180px-PDB_1j41_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ea/PDB_1j41_EBI.jpg/270px-PDB_1j41_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ea/PDB_1j41_EBI.jpg/360px-PDB_1j41_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1j41</b>: Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe) hemoglobin (laser photolysed)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1j7s_EBI.jpg" class="mw-file-description" title="1j7s: Crystal Structure of deoxy HbalphaYQ, a mutant of HbA"><img alt="1j7s: Crystal Structure of deoxy HbalphaYQ, a mutant of HbA" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/PDB_1j7s_EBI.jpg/180px-PDB_1j7s_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/PDB_1j7s_EBI.jpg/270px-PDB_1j7s_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/PDB_1j7s_EBI.jpg/360px-PDB_1j7s_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1j7s</b>: Crystal Structure of deoxy HbalphaYQ, a mutant of HbA</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1j7w_EBI.jpg" class="mw-file-description" title="1j7w: Crystal structure of deoxy HbbetaYQ, a site directed mutant of HbA"><img alt="1j7w: Crystal structure of deoxy HbbetaYQ, a site directed mutant of HbA" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/56/PDB_1j7w_EBI.jpg/180px-PDB_1j7w_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/56/PDB_1j7w_EBI.jpg/270px-PDB_1j7w_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/56/PDB_1j7w_EBI.jpg/360px-PDB_1j7w_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1j7w</b>: Crystal structure of deoxy HbbetaYQ, a site directed mutant of HbA</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1j7y_EBI.jpg" class="mw-file-description" title="1j7y: Crystal structure of partially ligated mutant of HbA"><img alt="1j7y: Crystal structure of partially ligated mutant of HbA" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1j7y_EBI.jpg/180px-PDB_1j7y_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1j7y_EBI.jpg/270px-PDB_1j7y_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1j7y_EBI.jpg/360px-PDB_1j7y_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1j7y</b>: Crystal structure of partially ligated mutant of HbA</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1jy7_EBI.jpg" class="mw-file-description" title="1jy7: THE STRUCTURE OF HUMAN METHEMOGLOBIN. THE VARIATION OF A THEME"><img alt="1jy7: THE STRUCTURE OF HUMAN METHEMOGLOBIN. THE VARIATION OF A THEME" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a6/PDB_1jy7_EBI.jpg/180px-PDB_1jy7_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a6/PDB_1jy7_EBI.jpg/270px-PDB_1jy7_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a6/PDB_1jy7_EBI.jpg/360px-PDB_1jy7_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1jy7</b>: THE STRUCTURE OF HUMAN METHEMOGLOBIN. THE VARIATION OF A THEME</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1k0y_EBI.jpg" class="mw-file-description" title="1k0y: X-ray Crystallographic Analyses of Symmetrical Allosteric Effectors of Hemoglobin. Compounds Designed to Link Primary and Secondary Binding Sites"><img alt="1k0y: X-ray Crystallographic Analyses of Symmetrical Allosteric Effectors of Hemoglobin. Compounds Designed to Link Primary and Secondary Binding Sites" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3c/PDB_1k0y_EBI.jpg/180px-PDB_1k0y_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3c/PDB_1k0y_EBI.jpg/270px-PDB_1k0y_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3c/PDB_1k0y_EBI.jpg/360px-PDB_1k0y_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1k0y</b>: X-ray Crystallographic Analyses of Symmetrical Allosteric Effectors of Hemoglobin. Compounds Designed to Link Primary and Secondary Binding Sites</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1k1k_EBI.jpg" class="mw-file-description" title="1k1k: Structure of Mutant Human Carbonmonoxyhemoglobin C (beta E6K) at 2.0 Angstrom Resolution in Phosphate Buffer."><img alt="1k1k: Structure of Mutant Human Carbonmonoxyhemoglobin C (beta E6K) at 2.0 Angstrom Resolution in Phosphate Buffer." src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8b/PDB_1k1k_EBI.jpg/180px-PDB_1k1k_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8b/PDB_1k1k_EBI.jpg/270px-PDB_1k1k_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8b/PDB_1k1k_EBI.jpg/360px-PDB_1k1k_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1k1k</b>: Structure of Mutant Human Carbonmonoxyhemoglobin C (beta E6K) at 2.0 Angstrom Resolution in Phosphate Buffer.</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1kd2_EBI.jpg" class="mw-file-description" title="1kd2: Crystal Structure of Human Deoxyhemoglobin in Absence of Any Anions"><img alt="1kd2: Crystal Structure of Human Deoxyhemoglobin in Absence of Any Anions" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/52/PDB_1kd2_EBI.jpg/180px-PDB_1kd2_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/52/PDB_1kd2_EBI.jpg/270px-PDB_1kd2_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/52/PDB_1kd2_EBI.jpg/360px-PDB_1kd2_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1kd2</b>: Crystal Structure of Human Deoxyhemoglobin in Absence of Any Anions</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1lfl_EBI.jpg" class="mw-file-description" title="1lfl: DEOXY HEMOGLOBIN (90% RELATIVE HUMIDITY)"><img alt="1lfl: DEOXY HEMOGLOBIN (90% RELATIVE HUMIDITY)" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/9d/PDB_1lfl_EBI.jpg/180px-PDB_1lfl_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/9d/PDB_1lfl_EBI.jpg/270px-PDB_1lfl_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/9d/PDB_1lfl_EBI.jpg/360px-PDB_1lfl_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1lfl</b>: DEOXY HEMOGLOBIN (90% RELATIVE HUMIDITY)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1lfq_EBI.jpg" class="mw-file-description" title="1lfq: OXY HEMOGLOBIN (93% RELATIVE HUMIDITY)"><img alt="1lfq: OXY HEMOGLOBIN (93% RELATIVE HUMIDITY)" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/99/PDB_1lfq_EBI.jpg/180px-PDB_1lfq_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/99/PDB_1lfq_EBI.jpg/270px-PDB_1lfq_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/99/PDB_1lfq_EBI.jpg/360px-PDB_1lfq_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1lfq</b>: OXY HEMOGLOBIN (93% RELATIVE HUMIDITY)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1lft_EBI.jpg" class="mw-file-description" title="1lft: OXY HEMOGLOBIN (90% RELATIVE HUMIDITY)"><img alt="1lft: OXY HEMOGLOBIN (90% RELATIVE HUMIDITY)" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/PDB_1lft_EBI.jpg/180px-PDB_1lft_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/PDB_1lft_EBI.jpg/270px-PDB_1lft_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/37/PDB_1lft_EBI.jpg/360px-PDB_1lft_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1lft</b>: OXY HEMOGLOBIN (90% RELATIVE HUMIDITY)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1lfv_EBI.jpg" class="mw-file-description" title="1lfv: OXY HEMOGLOBIN (88% RELATIVE HUMIDITY)"><img alt="1lfv: OXY HEMOGLOBIN (88% RELATIVE HUMIDITY)" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1lfv_EBI.jpg/180px-PDB_1lfv_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1lfv_EBI.jpg/270px-PDB_1lfv_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1lfv_EBI.jpg/360px-PDB_1lfv_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1lfv</b>: OXY HEMOGLOBIN (88% RELATIVE HUMIDITY)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1lfy_EBI.jpg" class="mw-file-description" title="1lfy: OXY HEMOGLOBIN (84% RELATIVE HUMIDITY)"><img alt="1lfy: OXY HEMOGLOBIN (84% RELATIVE HUMIDITY)" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1lfy_EBI.jpg/180px-PDB_1lfy_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1lfy_EBI.jpg/270px-PDB_1lfy_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1lfy_EBI.jpg/360px-PDB_1lfy_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1lfy</b>: OXY HEMOGLOBIN (84% RELATIVE HUMIDITY)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1lfz_EBI.jpg" class="mw-file-description" title="1lfz: OXY HEMOGLOBIN (25% METHANOL)"><img alt="1lfz: OXY HEMOGLOBIN (25% METHANOL)" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a9/PDB_1lfz_EBI.jpg/180px-PDB_1lfz_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a9/PDB_1lfz_EBI.jpg/270px-PDB_1lfz_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a9/PDB_1lfz_EBI.jpg/360px-PDB_1lfz_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1lfz</b>: OXY HEMOGLOBIN (25% METHANOL)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1ljw_EBI.jpg" class="mw-file-description" title="1ljw: Crystal Structure of Human Carbonmonoxy Hemoglobin at 2.16 A: A Snapshot of the Allosteric Transition"><img alt="1ljw: Crystal Structure of Human Carbonmonoxy Hemoglobin at 2.16 A: A Snapshot of the Allosteric Transition" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fd/PDB_1ljw_EBI.jpg/180px-PDB_1ljw_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fd/PDB_1ljw_EBI.jpg/270px-PDB_1ljw_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fd/PDB_1ljw_EBI.jpg/360px-PDB_1ljw_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1ljw</b>: Crystal Structure of Human Carbonmonoxy Hemoglobin at 2.16 A: A Snapshot of the Allosteric Transition</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1m9p_EBI.jpg" class="mw-file-description" title="1m9p: Crystalline Human Carbonmonoxy Hemoglobin C Exhibits The R2 Quaternary State at Neutral pH In The Presence of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure"><img alt="1m9p: Crystalline Human Carbonmonoxy Hemoglobin C Exhibits The R2 Quaternary State at Neutral pH In The Presence of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/79/PDB_1m9p_EBI.jpg/180px-PDB_1m9p_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/79/PDB_1m9p_EBI.jpg/270px-PDB_1m9p_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/79/PDB_1m9p_EBI.jpg/360px-PDB_1m9p_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1m9p</b>: Crystalline Human Carbonmonoxy Hemoglobin C Exhibits The R2 Quaternary State at Neutral pH In The Presence of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1mko_EBI.jpg" class="mw-file-description" title="1mko: A Fourth Quaternary Structure of Human Hemoglobin A at 2.18 A Resolution"><img alt="1mko: A Fourth Quaternary Structure of Human Hemoglobin A at 2.18 A Resolution" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_1mko_EBI.jpg/180px-PDB_1mko_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_1mko_EBI.jpg/270px-PDB_1mko_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_1mko_EBI.jpg/360px-PDB_1mko_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1mko</b>: A Fourth Quaternary Structure of Human Hemoglobin A at 2.18 A Resolution</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1nej_EBI.jpg" class="mw-file-description" title="1nej: Crystalline Human Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Exhibits The R2 Quaternary State At Neutral pH In The Presence Of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure"><img alt="1nej: Crystalline Human Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Exhibits The R2 Quaternary State At Neutral pH In The Presence Of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c9/PDB_1nej_EBI.jpg/180px-PDB_1nej_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c9/PDB_1nej_EBI.jpg/270px-PDB_1nej_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c9/PDB_1nej_EBI.jpg/360px-PDB_1nej_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1nej</b>: Crystalline Human Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Exhibits The R2 Quaternary State At Neutral pH In The Presence Of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1nih_EBI.jpg" class="mw-file-description" title="1nih: Structure of deoxy-quaternary haemoglobin with liganded beta subunits"><img alt="1nih: Structure of deoxy-quaternary haemoglobin with liganded beta subunits" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d2/PDB_1nih_EBI.jpg/180px-PDB_1nih_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d2/PDB_1nih_EBI.jpg/270px-PDB_1nih_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d2/PDB_1nih_EBI.jpg/360px-PDB_1nih_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1nih</b>: Structure of deoxy-quaternary haemoglobin with liganded beta subunits</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1nqp_EBI.jpg" class="mw-file-description" title="1nqp: Crystal structure of Human hemoglobin E at 1.73 A resolution"><img alt="1nqp: Crystal structure of Human hemoglobin E at 1.73 A resolution" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d5/PDB_1nqp_EBI.jpg/180px-PDB_1nqp_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d5/PDB_1nqp_EBI.jpg/270px-PDB_1nqp_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d5/PDB_1nqp_EBI.jpg/360px-PDB_1nqp_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1nqp</b>: Crystal structure of Human hemoglobin E at 1.73 A resolution</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1o1i_EBI.jpg" class="mw-file-description" title="1o1i: Cyanomet hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)"><img alt="1o1i: Cyanomet hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1o1i_EBI.jpg/180px-PDB_1o1i_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1o1i_EBI.jpg/270px-PDB_1o1i_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1o1i_EBI.jpg/360px-PDB_1o1i_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1o1i</b>: Cyanomet hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1o1j_EBI.jpg" class="mw-file-description" title="1o1j: Deoxy hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)"><img alt="1o1j: Deoxy hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/84/PDB_1o1j_EBI.jpg/180px-PDB_1o1j_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/84/PDB_1o1j_EBI.jpg/270px-PDB_1o1j_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/84/PDB_1o1j_EBI.jpg/360px-PDB_1o1j_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1o1j</b>: Deoxy hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1o1k_EBI.jpg" class="mw-file-description" title="1o1k: Deoxy hemoglobin (A,C:V1M; B,D:V1M,V67W)"><img alt="1o1k: Deoxy hemoglobin (A,C:V1M; B,D:V1M,V67W)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e6/PDB_1o1k_EBI.jpg/180px-PDB_1o1k_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e6/PDB_1o1k_EBI.jpg/270px-PDB_1o1k_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e6/PDB_1o1k_EBI.jpg/360px-PDB_1o1k_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1o1k</b>: Deoxy hemoglobin (A,C:V1M; B,D:V1M,V67W)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1o1l_EBI.jpg" class="mw-file-description" title="1o1l: Deoxy hemoglobin (A-GLY-C:V1M,L29W,H58Q; B,D:V1M)"><img alt="1o1l: Deoxy hemoglobin (A-GLY-C:V1M,L29W,H58Q; B,D:V1M)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1o1l_EBI.jpg/180px-PDB_1o1l_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1o1l_EBI.jpg/270px-PDB_1o1l_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1o1l_EBI.jpg/360px-PDB_1o1l_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1o1l</b>: Deoxy hemoglobin (A-GLY-C:V1M,L29W,H58Q; B,D:V1M)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1o1m_EBI.jpg" class="mw-file-description" title="1o1m: Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29F,H58Q B,D:V1M,V67W)"><img alt="1o1m: Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29F,H58Q B,D:V1M,V67W)" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d2/PDB_1o1m_EBI.jpg/180px-PDB_1o1m_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d2/PDB_1o1m_EBI.jpg/270px-PDB_1o1m_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d2/PDB_1o1m_EBI.jpg/360px-PDB_1o1m_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1o1m</b>: Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29F,H58Q B,D:V1M,V67W)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1o1n_EBI.jpg" class="mw-file-description" title="1o1n: Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29W; B,D:V1M)"><img alt="1o1n: Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29W; B,D:V1M)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1o1n_EBI.jpg/180px-PDB_1o1n_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1o1n_EBI.jpg/270px-PDB_1o1n_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1o1n_EBI.jpg/360px-PDB_1o1n_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1o1n</b>: Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29W; B,D:V1M)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1o1o_EBI.jpg" class="mw-file-description" title="1o1o: Deoxy hemoglobin (A,C:V1M,V62L; B,D:V1M,V67L)"><img alt="1o1o: Deoxy hemoglobin (A,C:V1M,V62L; B,D:V1M,V67L)" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3a/PDB_1o1o_EBI.jpg/180px-PDB_1o1o_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3a/PDB_1o1o_EBI.jpg/270px-PDB_1o1o_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3a/PDB_1o1o_EBI.jpg/360px-PDB_1o1o_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1o1o</b>: Deoxy hemoglobin (A,C:V1M,V62L; B,D:V1M,V67L)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1o1p_EBI.jpg" class="mw-file-description" title="1o1p: Deoxy hemoglobin (A-GLY-C:V1M; B,D:V1M,C93A,N108K)"><img alt="1o1p: Deoxy hemoglobin (A-GLY-C:V1M; B,D:V1M,C93A,N108K)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1o1p_EBI.jpg/180px-PDB_1o1p_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1o1p_EBI.jpg/270px-PDB_1o1p_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1o1p_EBI.jpg/360px-PDB_1o1p_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1o1p</b>: Deoxy hemoglobin (A-GLY-C:V1M; B,D:V1M,C93A,N108K)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1qi8_EBI.jpg" class="mw-file-description" title="1qi8: DEOXYGENATED STRUCTURE OF A DISTAL POCKET HEMOGLOBIN MUTANT"><img alt="1qi8: DEOXYGENATED STRUCTURE OF A DISTAL POCKET HEMOGLOBIN MUTANT" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/01/PDB_1qi8_EBI.jpg/180px-PDB_1qi8_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/01/PDB_1qi8_EBI.jpg/270px-PDB_1qi8_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/01/PDB_1qi8_EBI.jpg/360px-PDB_1qi8_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1qi8</b>: DEOXYGENATED STRUCTURE OF A DISTAL POCKET HEMOGLOBIN MUTANT</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1qsh_EBI.jpg" class="mw-file-description" title="1qsh: MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME"><img alt="1qsh: MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/cc/PDB_1qsh_EBI.jpg/180px-PDB_1qsh_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/cc/PDB_1qsh_EBI.jpg/270px-PDB_1qsh_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/cc/PDB_1qsh_EBI.jpg/360px-PDB_1qsh_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1qsh</b>: MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1qsi_EBI.jpg" class="mw-file-description" title="1qsi: MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME"><img alt="1qsi: MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3c/PDB_1qsi_EBI.jpg/180px-PDB_1qsi_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3c/PDB_1qsi_EBI.jpg/270px-PDB_1qsi_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3c/PDB_1qsi_EBI.jpg/360px-PDB_1qsi_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1qsi</b>: MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1qxd_EBI.jpg" class="mw-file-description" title="1qxd: Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds"><img alt="1qxd: Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1qxd_EBI.jpg/180px-PDB_1qxd_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1qxd_EBI.jpg/270px-PDB_1qxd_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1qxd_EBI.jpg/360px-PDB_1qxd_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1qxd</b>: Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1qxe_EBI.jpg" class="mw-file-description" title="1qxe: Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds"><img alt="1qxe: Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/PDB_1qxe_EBI.jpg/180px-PDB_1qxe_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/PDB_1qxe_EBI.jpg/270px-PDB_1qxe_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e4/PDB_1qxe_EBI.jpg/360px-PDB_1qxe_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1qxe</b>: Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1r1x_EBI.jpg" class="mw-file-description" title="1r1x: Crystal structure of oxy-human hemoglobin Bassett at 2.15 angstrom"><img alt="1r1x: Crystal structure of oxy-human hemoglobin Bassett at 2.15 angstrom" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b0/PDB_1r1x_EBI.jpg/180px-PDB_1r1x_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b0/PDB_1r1x_EBI.jpg/270px-PDB_1r1x_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b0/PDB_1r1x_EBI.jpg/360px-PDB_1r1x_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1r1x</b>: Crystal structure of oxy-human hemoglobin Bassett at 2.15 angstrom</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1r1y_EBI.jpg" class="mw-file-description" title="1r1y: Crystal structure of deoxy-human hemoglobin Bassett at 1.8 angstrom"><img alt="1r1y: Crystal structure of deoxy-human hemoglobin Bassett at 1.8 angstrom" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e2/PDB_1r1y_EBI.jpg/180px-PDB_1r1y_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e2/PDB_1r1y_EBI.jpg/270px-PDB_1r1y_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e2/PDB_1r1y_EBI.jpg/360px-PDB_1r1y_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1r1y</b>: Crystal structure of deoxy-human hemoglobin Bassett at 1.8 angstrom</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1rps_EBI.jpg" class="mw-file-description" title="1rps: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin. Hemoglobin exposed to NO under anerobic conditions"><img alt="1rps: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin. Hemoglobin exposed to NO under anerobic conditions" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PDB_1rps_EBI.jpg/180px-PDB_1rps_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PDB_1rps_EBI.jpg/270px-PDB_1rps_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PDB_1rps_EBI.jpg/360px-PDB_1rps_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1rps</b>: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin. Hemoglobin exposed to NO under anerobic conditions</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1rq3_EBI.jpg" class="mw-file-description" title="1rq3: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Deoxyhemoglobin, Deoxyhemoglobin"><img alt="1rq3: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Deoxyhemoglobin, Deoxyhemoglobin" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/52/PDB_1rq3_EBI.jpg/180px-PDB_1rq3_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/52/PDB_1rq3_EBI.jpg/270px-PDB_1rq3_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/52/PDB_1rq3_EBI.jpg/360px-PDB_1rq3_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1rq3</b>: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Deoxyhemoglobin, Deoxyhemoglobin</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1rq4_EBI.jpg" class="mw-file-description" title="1rq4: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin, HEMOGLOBIN EXPOSED TO NO UNDER AEROBIC CONDITIONS"><img alt="1rq4: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin, HEMOGLOBIN EXPOSED TO NO UNDER AEROBIC CONDITIONS" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b6/PDB_1rq4_EBI.jpg/180px-PDB_1rq4_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b6/PDB_1rq4_EBI.jpg/270px-PDB_1rq4_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b6/PDB_1rq4_EBI.jpg/360px-PDB_1rq4_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1rq4</b>: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin, HEMOGLOBIN EXPOSED TO NO UNDER AEROBIC CONDITIONS</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1rqa_EBI.jpg" class="mw-file-description" title="1rqa: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin. Beta W73E hemoglobin exposed to NO under anaerobic conditions"><img alt="1rqa: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin. Beta W73E hemoglobin exposed to NO under anaerobic conditions" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/PDB_1rqa_EBI.jpg/180px-PDB_1rqa_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/PDB_1rqa_EBI.jpg/270px-PDB_1rqa_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/83/PDB_1rqa_EBI.jpg/360px-PDB_1rqa_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1rqa</b>: Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin. Beta W73E hemoglobin exposed to NO under anaerobic conditions</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1rvw_EBI.jpg" class="mw-file-description" title="1rvw: R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY"><img alt="1rvw: R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f5/PDB_1rvw_EBI.jpg/180px-PDB_1rvw_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f5/PDB_1rvw_EBI.jpg/270px-PDB_1rvw_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f5/PDB_1rvw_EBI.jpg/360px-PDB_1rvw_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1rvw</b>: R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1sdk_EBI.jpg" class="mw-file-description" title="1sdk: CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A"><img alt="1sdk: CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/PDB_1sdk_EBI.jpg/180px-PDB_1sdk_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/PDB_1sdk_EBI.jpg/270px-PDB_1sdk_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/PDB_1sdk_EBI.jpg/360px-PDB_1sdk_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1sdk</b>: CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1sdl_EBI.jpg" class="mw-file-description" title="1sdl: CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A"><img alt="1sdl: CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6c/PDB_1sdl_EBI.jpg/180px-PDB_1sdl_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6c/PDB_1sdl_EBI.jpg/270px-PDB_1sdl_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6c/PDB_1sdl_EBI.jpg/360px-PDB_1sdl_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1sdl</b>: CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1shr_EBI.jpg" class="mw-file-description" title="1shr: Crystal structure of ferrocyanide bound human hemoglobin A2 at 1.88A resolution"><img alt="1shr: Crystal structure of ferrocyanide bound human hemoglobin A2 at 1.88A resolution" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_1shr_EBI.jpg/180px-PDB_1shr_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_1shr_EBI.jpg/270px-PDB_1shr_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PDB_1shr_EBI.jpg/360px-PDB_1shr_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1shr</b>: Crystal structure of ferrocyanide bound human hemoglobin A2 at 1.88A resolution</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1si4_EBI.jpg" class="mw-file-description" title="1si4: Crystal structure of Human hemoglobin A2 (in R2 state) at 2.2 A resolution"><img alt="1si4: Crystal structure of Human hemoglobin A2 (in R2 state) at 2.2 A resolution" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0a/PDB_1si4_EBI.jpg/180px-PDB_1si4_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0a/PDB_1si4_EBI.jpg/270px-PDB_1si4_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0a/PDB_1si4_EBI.jpg/360px-PDB_1si4_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1si4</b>: Crystal structure of Human hemoglobin A2 (in R2 state) at 2.2 A resolution</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1thb_EBI.jpg" class="mw-file-description" title="1thb: REFINEMENT OF A PARTIALLY OXYGENATED T STATE HAEMOGLOBIN AT 1.5 ANGSTROMS RESOLUTION"><img alt="1thb: REFINEMENT OF A PARTIALLY OXYGENATED T STATE HAEMOGLOBIN AT 1.5 ANGSTROMS RESOLUTION" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/ae/PDB_1thb_EBI.jpg/180px-PDB_1thb_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/ae/PDB_1thb_EBI.jpg/270px-PDB_1thb_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/ae/PDB_1thb_EBI.jpg/360px-PDB_1thb_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1thb</b>: REFINEMENT OF A PARTIALLY OXYGENATED T STATE HAEMOGLOBIN AT 1.5 ANGSTROMS RESOLUTION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1uiw_EBI.jpg" class="mw-file-description" title="1uiw: Crystal Structures of Unliganded and Half-Liganded Human Hemoglobin Derivatives Cross-Linked between Lys 82beta1 and Lys 82beta2"><img alt="1uiw: Crystal Structures of Unliganded and Half-Liganded Human Hemoglobin Derivatives Cross-Linked between Lys 82beta1 and Lys 82beta2" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/23/PDB_1uiw_EBI.jpg/180px-PDB_1uiw_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/23/PDB_1uiw_EBI.jpg/270px-PDB_1uiw_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/23/PDB_1uiw_EBI.jpg/360px-PDB_1uiw_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1uiw</b>: Crystal Structures of Unliganded and Half-Liganded Human Hemoglobin Derivatives Cross-Linked between Lys 82beta1 and Lys 82beta2</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1vwt_EBI.jpg" class="mw-file-description" title="1vwt: T STATE HUMAN HEMOGLOBIN [ALPHA V96W], ALPHA AQUOMET, BETA DEOXY"><img alt="1vwt: T STATE HUMAN HEMOGLOBIN [ALPHA V96W], ALPHA AQUOMET, BETA DEOXY" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/75/PDB_1vwt_EBI.jpg/180px-PDB_1vwt_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/75/PDB_1vwt_EBI.jpg/270px-PDB_1vwt_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/75/PDB_1vwt_EBI.jpg/360px-PDB_1vwt_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1vwt</b>: T STATE HUMAN HEMOGLOBIN [ALPHA V96W], ALPHA AQUOMET, BETA DEOXY</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xxt_EBI.jpg" class="mw-file-description" title="1xxt: The T-to-T High Transitions in Human Hemoglobin: wild-type deoxy Hb A (low salt, one test set)"><img alt="1xxt: The T-to-T High Transitions in Human Hemoglobin: wild-type deoxy Hb A (low salt, one test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/9b/PDB_1xxt_EBI.jpg/180px-PDB_1xxt_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/9b/PDB_1xxt_EBI.jpg/270px-PDB_1xxt_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/9b/PDB_1xxt_EBI.jpg/360px-PDB_1xxt_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xxt</b>: The T-to-T High Transitions in Human Hemoglobin: wild-type deoxy Hb A (low salt, one test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xy0_EBI.jpg" class="mw-file-description" title="1xy0: T-to-THigh Transitions in Human Hemoglobin: alphaK40G deoxy low-salt"><img alt="1xy0: T-to-THigh Transitions in Human Hemoglobin: alphaK40G deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/41/PDB_1xy0_EBI.jpg/180px-PDB_1xy0_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/41/PDB_1xy0_EBI.jpg/270px-PDB_1xy0_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/41/PDB_1xy0_EBI.jpg/360px-PDB_1xy0_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xy0</b>: T-to-THigh Transitions in Human Hemoglobin: alphaK40G deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xye_EBI.jpg" class="mw-file-description" title="1xye: T-to-THigh Transitions in Human Hemoglobin: alpha Y42A deoxy low salt"><img alt="1xye: T-to-THigh Transitions in Human Hemoglobin: alpha Y42A deoxy low salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/PDB_1xye_EBI.jpg/180px-PDB_1xye_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/PDB_1xye_EBI.jpg/270px-PDB_1xye_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f3/PDB_1xye_EBI.jpg/360px-PDB_1xye_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xye</b>: T-to-THigh Transitions in Human Hemoglobin: alpha Y42A deoxy low salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xz2_EBI.jpg" class="mw-file-description" title="1xz2: wild-type hemoglobin deoxy no-salt"><img alt="1xz2: wild-type hemoglobin deoxy no-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_1xz2_EBI.jpg/180px-PDB_1xz2_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_1xz2_EBI.jpg/270px-PDB_1xz2_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_1xz2_EBI.jpg/360px-PDB_1xz2_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xz2</b>: wild-type hemoglobin deoxy no-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xz4_EBI.jpg" class="mw-file-description" title="1xz4: Intersubunit Interactions Associated with Tyr42alpha Stabilize the Quaternary-T Tetramer but are not Major Quaternary Constraints in Deoxyhemoglobin: alphaY42A deoxyhemoglobin no-salt"><img alt="1xz4: Intersubunit Interactions Associated with Tyr42alpha Stabilize the Quaternary-T Tetramer but are not Major Quaternary Constraints in Deoxyhemoglobin: alphaY42A deoxyhemoglobin no-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6d/PDB_1xz4_EBI.jpg/180px-PDB_1xz4_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6d/PDB_1xz4_EBI.jpg/270px-PDB_1xz4_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6d/PDB_1xz4_EBI.jpg/360px-PDB_1xz4_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xz4</b>: Intersubunit Interactions Associated with Tyr42alpha Stabilize the Quaternary-T Tetramer but are not Major Quaternary Constraints in Deoxyhemoglobin: alphaY42A deoxyhemoglobin no-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xz5_EBI.jpg" class="mw-file-description" title="1xz5: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaL91A deoxy low-salt"><img alt="1xz5: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaL91A deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f9/PDB_1xz5_EBI.jpg/180px-PDB_1xz5_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f9/PDB_1xz5_EBI.jpg/270px-PDB_1xz5_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f9/PDB_1xz5_EBI.jpg/360px-PDB_1xz5_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xz5</b>: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaL91A deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xz7_EBI.jpg" class="mw-file-description" title="1xz7: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaR92A deoxy low-salt"><img alt="1xz7: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaR92A deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/95/PDB_1xz7_EBI.jpg/180px-PDB_1xz7_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/95/PDB_1xz7_EBI.jpg/270px-PDB_1xz7_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/95/PDB_1xz7_EBI.jpg/360px-PDB_1xz7_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xz7</b>: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaR92A deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xzu_EBI.jpg" class="mw-file-description" title="1xzu: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaD94G deoxy low-salt"><img alt="1xzu: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaD94G deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a8/PDB_1xzu_EBI.jpg/180px-PDB_1xzu_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a8/PDB_1xzu_EBI.jpg/270px-PDB_1xzu_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a8/PDB_1xzu_EBI.jpg/360px-PDB_1xzu_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xzu</b>: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaD94G deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1xzv_EBI.jpg" class="mw-file-description" title="1xzv: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaP95A deoxy low-salt"><img alt="1xzv: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaP95A deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1xzv_EBI.jpg/180px-PDB_1xzv_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1xzv_EBI.jpg/270px-PDB_1xzv_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1xzv_EBI.jpg/360px-PDB_1xzv_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1xzv</b>: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaP95A deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y09_EBI.jpg" class="mw-file-description" title="1y09: T-to-T(High) Quaternary Transitions in Human Hemoglobin: alphaN97A deoxy low-salt"><img alt="1y09: T-to-T(High) Quaternary Transitions in Human Hemoglobin: alphaN97A deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/1a/PDB_1y09_EBI.jpg/180px-PDB_1y09_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/1a/PDB_1y09_EBI.jpg/270px-PDB_1y09_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/1a/PDB_1y09_EBI.jpg/360px-PDB_1y09_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y09</b>: T-to-T(High) Quaternary Transitions in Human Hemoglobin: alphaN97A deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y0a_EBI.jpg" class="mw-file-description" title="1y0a: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaY140A deoxy low-salt"><img alt="1y0a: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaY140A deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bc/PDB_1y0a_EBI.jpg/180px-PDB_1y0a_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bc/PDB_1y0a_EBI.jpg/270px-PDB_1y0a_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bc/PDB_1y0a_EBI.jpg/360px-PDB_1y0a_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y0a</b>: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaY140A deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y0c_EBI.jpg" class="mw-file-description" title="1y0c: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaY140F deoxy low-salt"><img alt="1y0c: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaY140F deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/93/PDB_1y0c_EBI.jpg/180px-PDB_1y0c_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/93/PDB_1y0c_EBI.jpg/270px-PDB_1y0c_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/93/PDB_1y0c_EBI.jpg/360px-PDB_1y0c_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y0c</b>: T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaY140F deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y0d_EBI.jpg" class="mw-file-description" title="1y0d: T-to-THigh Quaternary Transitions in Human Hemoglobin: desArg141alpha deoxy low-salt"><img alt="1y0d: T-to-THigh Quaternary Transitions in Human Hemoglobin: desArg141alpha deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_1y0d_EBI.jpg/180px-PDB_1y0d_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_1y0d_EBI.jpg/270px-PDB_1y0d_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_1y0d_EBI.jpg/360px-PDB_1y0d_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y0d</b>: T-to-THigh Quaternary Transitions in Human Hemoglobin: desArg141alpha deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y0t_EBI.jpg" class="mw-file-description" title="1y0t: T-to-T(High) Quaternary Transitions in Human Hemoglobin: betaV1M deoxy low-salt (1 test set)"><img alt="1y0t: T-to-T(High) Quaternary Transitions in Human Hemoglobin: betaV1M deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/PDB_1y0t_EBI.jpg/180px-PDB_1y0t_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/PDB_1y0t_EBI.jpg/270px-PDB_1y0t_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dc/PDB_1y0t_EBI.jpg/360px-PDB_1y0t_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y0t</b>: T-to-T(High) Quaternary Transitions in Human Hemoglobin: betaV1M deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y0w_EBI.jpg" class="mw-file-description" title="1y0w: T-to-THigh quaternary Transitions in Human Hemoglobin: betaV1M deoxy low-salt (10 test sets)"><img alt="1y0w: T-to-THigh quaternary Transitions in Human Hemoglobin: betaV1M deoxy low-salt (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/PDB_1y0w_EBI.jpg/180px-PDB_1y0w_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/PDB_1y0w_EBI.jpg/270px-PDB_1y0w_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/37/PDB_1y0w_EBI.jpg/360px-PDB_1y0w_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y0w</b>: T-to-THigh quaternary Transitions in Human Hemoglobin: betaV1M deoxy low-salt (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y22_EBI.jpg" class="mw-file-description" title="1y22: T-To-T(High) quaternary transitions in human hemoglobin: betaV33A deoxy low-salt (1 test set)"><img alt="1y22: T-To-T(High) quaternary transitions in human hemoglobin: betaV33A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bf/PDB_1y22_EBI.jpg/180px-PDB_1y22_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bf/PDB_1y22_EBI.jpg/270px-PDB_1y22_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bf/PDB_1y22_EBI.jpg/360px-PDB_1y22_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y22</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaV33A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y2z_EBI.jpg" class="mw-file-description" title="1y2z: T-To-T(High) quaternary transitions in human hemoglobin: betaV34G deoxy low-salt (1 test set)"><img alt="1y2z: T-To-T(High) quaternary transitions in human hemoglobin: betaV34G deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/PDB_1y2z_EBI.jpg/180px-PDB_1y2z_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/PDB_1y2z_EBI.jpg/270px-PDB_1y2z_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a5/PDB_1y2z_EBI.jpg/360px-PDB_1y2z_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y2z</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaV34G deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y31_EBI.jpg" class="mw-file-description" title="1y31: T-To-T(High) quaternary transitions in human hemoglobin: betaY35A deoxy low-salt (1 test set)"><img alt="1y31: T-To-T(High) quaternary transitions in human hemoglobin: betaY35A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c2/PDB_1y31_EBI.jpg/180px-PDB_1y31_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c2/PDB_1y31_EBI.jpg/270px-PDB_1y31_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c2/PDB_1y31_EBI.jpg/360px-PDB_1y31_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y31</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaY35A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y35_EBI.jpg" class="mw-file-description" title="1y35: T-To-T(High) quaternary transitions in human hemoglobin: betaY35F deoxy low-salt (1 test set)"><img alt="1y35: T-To-T(High) quaternary transitions in human hemoglobin: betaY35F deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1y35_EBI.jpg/180px-PDB_1y35_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1y35_EBI.jpg/270px-PDB_1y35_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_1y35_EBI.jpg/360px-PDB_1y35_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y35</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaY35F deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y45_EBI.jpg" class="mw-file-description" title="1y45: T-To-T(high) quaternary transitions in human hemoglobin: betaP36A deoxy low-salt (10 test sets)"><img alt="1y45: T-To-T(high) quaternary transitions in human hemoglobin: betaP36A deoxy low-salt (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1y45_EBI.jpg/180px-PDB_1y45_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1y45_EBI.jpg/270px-PDB_1y45_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ed/PDB_1y45_EBI.jpg/360px-PDB_1y45_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y45</b>: T-To-T(high) quaternary transitions in human hemoglobin: betaP36A deoxy low-salt (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y46_EBI.jpg" class="mw-file-description" title="1y46: T-To-T(High) quaternary transitions in human hemoglobin: betaW37Y deoxy low-salt (10 test sets)"><img alt="1y46: T-To-T(High) quaternary transitions in human hemoglobin: betaW37Y deoxy low-salt (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/24/PDB_1y46_EBI.jpg/180px-PDB_1y46_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/24/PDB_1y46_EBI.jpg/270px-PDB_1y46_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/24/PDB_1y46_EBI.jpg/360px-PDB_1y46_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y46</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaW37Y deoxy low-salt (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y4b_EBI.jpg" class="mw-file-description" title="1y4b: T-To-T(High) quaternary transitions in human hemoglobin: betaW37H deoxy low-salt (10 test sets)"><img alt="1y4b: T-To-T(High) quaternary transitions in human hemoglobin: betaW37H deoxy low-salt (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d0/PDB_1y4b_EBI.jpg/180px-PDB_1y4b_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d0/PDB_1y4b_EBI.jpg/270px-PDB_1y4b_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d0/PDB_1y4b_EBI.jpg/360px-PDB_1y4b_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y4b</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaW37H deoxy low-salt (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y4f_EBI.jpg" class="mw-file-description" title="1y4f: T-To-T(High) quaternary transitions in human hemoglobin: betaW37A deoxy low-salt (10 test sets)"><img alt="1y4f: T-To-T(High) quaternary transitions in human hemoglobin: betaW37A deoxy low-salt (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/29/PDB_1y4f_EBI.jpg/180px-PDB_1y4f_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/29/PDB_1y4f_EBI.jpg/270px-PDB_1y4f_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/29/PDB_1y4f_EBI.jpg/360px-PDB_1y4f_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y4f</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaW37A deoxy low-salt (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y4g_EBI.jpg" class="mw-file-description" title="1y4g: T-To-T(High) quaternary transitions in human hemoglobin: betaW37G deoxy low-salt (10 test sets)"><img alt="1y4g: T-To-T(High) quaternary transitions in human hemoglobin: betaW37G deoxy low-salt (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1y4g_EBI.jpg/180px-PDB_1y4g_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1y4g_EBI.jpg/270px-PDB_1y4g_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1y4g_EBI.jpg/360px-PDB_1y4g_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y4g</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaW37G deoxy low-salt (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y4p_EBI.jpg" class="mw-file-description" title="1y4p: T-To-T(high) quaternary transitions in human hemoglobin: betaW37E deoxy low-salt (10 test sets)"><img alt="1y4p: T-To-T(high) quaternary transitions in human hemoglobin: betaW37E deoxy low-salt (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/55/PDB_1y4p_EBI.jpg/180px-PDB_1y4p_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/55/PDB_1y4p_EBI.jpg/270px-PDB_1y4p_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/55/PDB_1y4p_EBI.jpg/360px-PDB_1y4p_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y4p</b>: T-To-T(high) quaternary transitions in human hemoglobin: betaW37E deoxy low-salt (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y4q_EBI.jpg" class="mw-file-description" title="1y4q: T-To-T(High) quaternary transitions in human hemoglobin: betaF42A deoxy low-salt (1 test set)"><img alt="1y4q: T-To-T(High) quaternary transitions in human hemoglobin: betaF42A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/PDB_1y4q_EBI.jpg/180px-PDB_1y4q_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/PDB_1y4q_EBI.jpg/270px-PDB_1y4q_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/83/PDB_1y4q_EBI.jpg/360px-PDB_1y4q_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y4q</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaF42A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y4r_EBI.jpg" class="mw-file-description" title="1y4r: T-To-T(High) quaternary transitions in human hemoglobin: betaF45A deoxy low-salt (1 test set)"><img alt="1y4r: T-To-T(High) quaternary transitions in human hemoglobin: betaF45A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/19/PDB_1y4r_EBI.jpg/180px-PDB_1y4r_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/19/PDB_1y4r_EBI.jpg/270px-PDB_1y4r_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/19/PDB_1y4r_EBI.jpg/360px-PDB_1y4r_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y4r</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaF45A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y4v_EBI.jpg" class="mw-file-description" title="1y4v: T-To-T(High) quaternary transitions in human hemoglobin: betaC93A deoxy low-salt (1 test set)"><img alt="1y4v: T-To-T(High) quaternary transitions in human hemoglobin: betaC93A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c5/PDB_1y4v_EBI.jpg/180px-PDB_1y4v_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c5/PDB_1y4v_EBI.jpg/270px-PDB_1y4v_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c5/PDB_1y4v_EBI.jpg/360px-PDB_1y4v_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y4v</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaC93A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y5f_EBI.jpg" class="mw-file-description" title="1y5f: T-To-T(High) quaternary transitions in human hemoglobin: betaL96A deoxy low-salt (1 test set)"><img alt="1y5f: T-To-T(High) quaternary transitions in human hemoglobin: betaL96A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e3/PDB_1y5f_EBI.jpg/180px-PDB_1y5f_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e3/PDB_1y5f_EBI.jpg/270px-PDB_1y5f_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e3/PDB_1y5f_EBI.jpg/360px-PDB_1y5f_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y5f</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaL96A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y5j_EBI.jpg" class="mw-file-description" title="1y5j: T-To-T(High) quaternary transitions in human hemoglobin: betaH97A deoxy low-salt (1 test set)"><img alt="1y5j: T-To-T(High) quaternary transitions in human hemoglobin: betaH97A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/31/PDB_1y5j_EBI.jpg/180px-PDB_1y5j_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/31/PDB_1y5j_EBI.jpg/270px-PDB_1y5j_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/31/PDB_1y5j_EBI.jpg/360px-PDB_1y5j_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y5j</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaH97A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y5k_EBI.jpg" class="mw-file-description" title="1y5k: T-To-T(High) quaternary transitions in human hemoglobin: betaD99A deoxy low-salt (10 test sets)"><img alt="1y5k: T-To-T(High) quaternary transitions in human hemoglobin: betaD99A deoxy low-salt (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1y5k_EBI.jpg/180px-PDB_1y5k_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1y5k_EBI.jpg/270px-PDB_1y5k_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_1y5k_EBI.jpg/360px-PDB_1y5k_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y5k</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaD99A deoxy low-salt (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y7c_EBI.jpg" class="mw-file-description" title="1y7c: T-To-T(High) quaternary transitions in human hemoglobin: betaP100A deoxy low-salt (1 test set)"><img alt="1y7c: T-To-T(High) quaternary transitions in human hemoglobin: betaP100A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d3/PDB_1y7c_EBI.jpg/180px-PDB_1y7c_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d3/PDB_1y7c_EBI.jpg/270px-PDB_1y7c_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d3/PDB_1y7c_EBI.jpg/360px-PDB_1y7c_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y7c</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaP100A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y7d_EBI.jpg" class="mw-file-description" title="1y7d: T-To-T(High) quaternary transitions in human hemoglobin: betaP100G deoxy low-salt (1 test set)"><img alt="1y7d: T-To-T(High) quaternary transitions in human hemoglobin: betaP100G deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3a/PDB_1y7d_EBI.jpg/180px-PDB_1y7d_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3a/PDB_1y7d_EBI.jpg/270px-PDB_1y7d_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3a/PDB_1y7d_EBI.jpg/360px-PDB_1y7d_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y7d</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaP100G deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y7g_EBI.jpg" class="mw-file-description" title="1y7g: T-To-T(high) quaternary transitions in human hemoglobin: betaN102A deoxy low-salt (1 test set)"><img alt="1y7g: T-To-T(high) quaternary transitions in human hemoglobin: betaN102A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/31/PDB_1y7g_EBI.jpg/180px-PDB_1y7g_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/31/PDB_1y7g_EBI.jpg/270px-PDB_1y7g_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/31/PDB_1y7g_EBI.jpg/360px-PDB_1y7g_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y7g</b>: T-To-T(high) quaternary transitions in human hemoglobin: betaN102A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y7z_EBI.jpg" class="mw-file-description" title="1y7z: T-To-T(High) quaternary transitions in human hemoglobin: betaN108A deoxy low-salt (1 test set)"><img alt="1y7z: T-To-T(High) quaternary transitions in human hemoglobin: betaN108A deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/92/PDB_1y7z_EBI.jpg/180px-PDB_1y7z_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/92/PDB_1y7z_EBI.jpg/270px-PDB_1y7z_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/92/PDB_1y7z_EBI.jpg/360px-PDB_1y7z_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y7z</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaN108A deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y83_EBI.jpg" class="mw-file-description" title="1y83: T-To-T(High) quaternary transitions in human hemoglobin: betaY145G deoxy low-salt (1 test set)"><img alt="1y83: T-To-T(High) quaternary transitions in human hemoglobin: betaY145G deoxy low-salt (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/15/PDB_1y83_EBI.jpg/180px-PDB_1y83_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/15/PDB_1y83_EBI.jpg/270px-PDB_1y83_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/15/PDB_1y83_EBI.jpg/360px-PDB_1y83_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y83</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaY145G deoxy low-salt (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y85_EBI.jpg" class="mw-file-description" title="1y85: T-To-T(High) quaternary transitions in human hemoglobin: desHIS146beta deoxy low-salt"><img alt="1y85: T-To-T(High) quaternary transitions in human hemoglobin: desHIS146beta deoxy low-salt" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/7b/PDB_1y85_EBI.jpg/180px-PDB_1y85_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/7b/PDB_1y85_EBI.jpg/270px-PDB_1y85_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/7b/PDB_1y85_EBI.jpg/360px-PDB_1y85_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y85</b>: T-To-T(High) quaternary transitions in human hemoglobin: desHIS146beta deoxy low-salt</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1y8w_EBI.jpg" class="mw-file-description" title="1y8w: T-To-T(High) quaternary transitions in human hemoglobin: alphaR92A oxy (2mM IHP, 20% PEG) (10 test sets)"><img alt="1y8w: T-To-T(High) quaternary transitions in human hemoglobin: alphaR92A oxy (2mM IHP, 20% PEG) (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/PDB_1y8w_EBI.jpg/180px-PDB_1y8w_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/PDB_1y8w_EBI.jpg/270px-PDB_1y8w_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/5b/PDB_1y8w_EBI.jpg/360px-PDB_1y8w_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1y8w</b>: T-To-T(High) quaternary transitions in human hemoglobin: alphaR92A oxy (2mM IHP, 20% PEG) (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1ydz_EBI.jpg" class="mw-file-description" title="1ydz: T-To-T(High) quaternary transitions in human hemoglobin: alphaY140F oxy (2MM IHP, 20% PEG) (1 test set)"><img alt="1ydz: T-To-T(High) quaternary transitions in human hemoglobin: alphaY140F oxy (2MM IHP, 20% PEG) (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/9a/PDB_1ydz_EBI.jpg/180px-PDB_1ydz_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/9a/PDB_1ydz_EBI.jpg/270px-PDB_1ydz_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/9a/PDB_1ydz_EBI.jpg/360px-PDB_1ydz_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1ydz</b>: T-To-T(High) quaternary transitions in human hemoglobin: alphaY140F oxy (2MM IHP, 20% PEG) (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1ye0_EBI.jpg" class="mw-file-description" title="1ye0: T-To-T(High) quaternary transitions in human hemoglobin: betaV33A oxy (2MM IHP, 20% PEG) (1 test set)"><img alt="1ye0: T-To-T(High) quaternary transitions in human hemoglobin: betaV33A oxy (2MM IHP, 20% PEG) (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1ye0_EBI.jpg/180px-PDB_1ye0_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1ye0_EBI.jpg/270px-PDB_1ye0_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0d/PDB_1ye0_EBI.jpg/360px-PDB_1ye0_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1ye0</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaV33A oxy (2MM IHP, 20% PEG) (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1ye1_EBI.jpg" class="mw-file-description" title="1ye1: T-To-T(High) quaternary transitions in human hemoglobin: betaY35A oxy (2MM IHP, 20% PEG) (1 test set)"><img alt="1ye1: T-To-T(High) quaternary transitions in human hemoglobin: betaY35A oxy 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betaY35F oxy (2MM IHP, 20% PEG) (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/PDB_1ye2_EBI.jpg/180px-PDB_1ye2_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/PDB_1ye2_EBI.jpg/270px-PDB_1ye2_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3e/PDB_1ye2_EBI.jpg/360px-PDB_1ye2_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1ye2</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaY35F oxy (2MM IHP, 20% PEG) (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yen_EBI.jpg" class="mw-file-description" title="1yen: T-To-T(High) quaternary transitions in human hemoglobin: betaP36A oxy (2MM IHP, 20% PEG) (10 test sets)"><img alt="1yen: T-To-T(High) quaternary transitions in human 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hemoglobin: betaW37A OXY (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/17/PDB_1yeo_EBI.jpg/180px-PDB_1yeo_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/17/PDB_1yeo_EBI.jpg/270px-PDB_1yeo_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/17/PDB_1yeo_EBI.jpg/360px-PDB_1yeo_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yeo</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaW37A OXY (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yeq_EBI.jpg" class="mw-file-description" title="1yeq: T-To-T(High) quaternary transitions in human hemoglobin: betaW37Y OXY (10 test sets)"><img alt="1yeq: T-To-T(High) quaternary transitions in human hemoglobin: betaW37Y OXY (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/PDB_1yeq_EBI.jpg/180px-PDB_1yeq_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/PDB_1yeq_EBI.jpg/270px-PDB_1yeq_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4c/PDB_1yeq_EBI.jpg/360px-PDB_1yeq_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yeq</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaW37Y OXY (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yeu_EBI.jpg" class="mw-file-description" title="1yeu: T-To-T(High) quaternary transitions in human hemoglobin: betaW37G OXY (10 test sets)"><img alt="1yeu: T-To-T(High) quaternary transitions in human hemoglobin: betaW37G OXY (10 test sets)" 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src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c4/PDB_1yff_EBI.jpg/180px-PDB_1yff_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c4/PDB_1yff_EBI.jpg/270px-PDB_1yff_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c4/PDB_1yff_EBI.jpg/360px-PDB_1yff_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yff</b>: STRUCTURE OF HUMAN CARBONMONOXYHEMOGLOBIN C (BETA E6K): TWO QUATERNARY STATES (R2 and R3) IN ONE CRYSTAL</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yg5_EBI.jpg" class="mw-file-description" title="1yg5: T-To-T(High) quaternary transitions in human hemoglobin: betaW37H OXY (2MM IHP, 20% PEG) (10 test sets)"><img alt="1yg5: T-To-T(High) quaternary transitions in human hemoglobin: betaW37H OXY (2MM IHP, 20% PEG) (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/80/PDB_1yg5_EBI.jpg/180px-PDB_1yg5_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/80/PDB_1yg5_EBI.jpg/270px-PDB_1yg5_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/80/PDB_1yg5_EBI.jpg/360px-PDB_1yg5_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yg5</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaW37H OXY (2MM IHP, 20% PEG) (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1ygd_EBI.jpg" class="mw-file-description" title="1ygd: T-To-T(High) quaternary transitions in human hemoglobin: betaW37E alpha zinc beta oxy (10 TEST SETS)"><img alt="1ygd: T-To-T(High) quaternary transitions in human hemoglobin: betaW37E alpha zinc beta oxy (10 TEST SETS)" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/59/PDB_1ygd_EBI.jpg/180px-PDB_1ygd_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/59/PDB_1ygd_EBI.jpg/270px-PDB_1ygd_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/59/PDB_1ygd_EBI.jpg/360px-PDB_1ygd_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1ygd</b>: T-To-T(High) quaternary transitions in human hemoglobin: betaW37E alpha zinc beta oxy (10 TEST SETS)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1ygf_EBI.jpg" class="mw-file-description" title="1ygf: T-to-T(high) quaternary transitions in human hemoglobin: betaH97A oxy (2MM IHP, 20% PEG) (1 test set)"><img alt="1ygf: T-to-T(high) quaternary transitions in human hemoglobin: betaH97A oxy (2MM IHP, 20% PEG) (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/67/PDB_1ygf_EBI.jpg/180px-PDB_1ygf_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/67/PDB_1ygf_EBI.jpg/270px-PDB_1ygf_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/67/PDB_1ygf_EBI.jpg/360px-PDB_1ygf_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1ygf</b>: T-to-T(high) quaternary transitions in human hemoglobin: betaH97A oxy (2MM IHP, 20% PEG) (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yh9_EBI.jpg" class="mw-file-description" title="1yh9: T-to-T(High) quaternary transitions in human hemoglobin: HbA OXY (2MM IHP, 20% PEG) (10 test sets)"><img alt="1yh9: T-to-T(High) quaternary transitions in human hemoglobin: HbA OXY 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HbA OXY (10.0MM IHP, 20% PEG) (10 test sets)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1yhr_EBI.jpg/180px-PDB_1yhr_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1yhr_EBI.jpg/270px-PDB_1yhr_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1yhr_EBI.jpg/360px-PDB_1yhr_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yhr</b>: T-To-T(High) quaternary transitions in human hemoglobin: HbA OXY (10.0MM IHP, 20% PEG) (10 test sets)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yie_EBI.jpg" class="mw-file-description" title="1yie: T-to-thigh quaternary transitions in human hemoglobin: betaW37A oxy (2.2MM IHP, 13% PEG) (1 test set)"><img alt="1yie: T-to-thigh quaternary transitions in human hemoglobin: betaW37A oxy (2.2MM IHP, 13% PEG) (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/db/PDB_1yie_EBI.jpg/180px-PDB_1yie_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/db/PDB_1yie_EBI.jpg/270px-PDB_1yie_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/db/PDB_1yie_EBI.jpg/360px-PDB_1yie_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yie</b>: T-to-thigh quaternary transitions in human hemoglobin: betaW37A oxy (2.2MM IHP, 13% PEG) (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yih_EBI.jpg" class="mw-file-description" title="1yih: T-to-T(High) quaternary transitions in human hemoglobin: betaP100A oxy (2.2MM IHP, 20% PEG) (1 test set)"><img alt="1yih: T-to-T(High) quaternary transitions in human hemoglobin: betaP100A oxy (2.2MM IHP, 20% PEG) (1 test set)" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f4/PDB_1yih_EBI.jpg/180px-PDB_1yih_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f4/PDB_1yih_EBI.jpg/270px-PDB_1yih_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f4/PDB_1yih_EBI.jpg/360px-PDB_1yih_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yih</b>: T-to-T(High) quaternary transitions in human hemoglobin: betaP100A oxy (2.2MM IHP, 20% PEG) (1 test set)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yvq_EBI.jpg" class="mw-file-description" title="1yvq: The low salt (PEG) crystal structure of CO Hemoglobin E (betaE26K) approaching physiological pH (pH 7.5)"><img alt="1yvq: The low salt (PEG) crystal structure of CO Hemoglobin E (betaE26K) approaching physiological pH (pH 7.5)" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/28/PDB_1yvq_EBI.jpg/180px-PDB_1yvq_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/28/PDB_1yvq_EBI.jpg/270px-PDB_1yvq_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/28/PDB_1yvq_EBI.jpg/360px-PDB_1yvq_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yvq</b>: The low salt (PEG) crystal structure of CO Hemoglobin E (betaE26K) approaching physiological pH (pH 7.5)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yvt_EBI.jpg" class="mw-file-description" title="1yvt: The high salt (phosphate) crystal structure of CO Hemoglobin E (Glu26Lys) at physiological pH (pH 7.35)"><img alt="1yvt: The high salt (phosphate) crystal structure of CO Hemoglobin E (Glu26Lys) at physiological pH (pH 7.35)" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/PDB_1yvt_EBI.jpg/180px-PDB_1yvt_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/PDB_1yvt_EBI.jpg/270px-PDB_1yvt_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/08/PDB_1yvt_EBI.jpg/360px-PDB_1yvt_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yvt</b>: The high salt (phosphate) crystal structure of CO Hemoglobin E (Glu26Lys) at physiological pH (pH 7.35)</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1yzi_EBI.jpg" class="mw-file-description" title="1yzi: A novel quaternary structure of human carbonmonoxy hemoglobin"><img alt="1yzi: A novel quaternary structure of human carbonmonoxy hemoglobin" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/PDB_1yzi_EBI.jpg/180px-PDB_1yzi_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/PDB_1yzi_EBI.jpg/270px-PDB_1yzi_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/PDB_1yzi_EBI.jpg/360px-PDB_1yzi_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1yzi</b>: A novel quaternary structure of human carbonmonoxy hemoglobin</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2d5z_EBI.jpg" class="mw-file-description" title="2d5z: Crystal structure of T-state human hemoglobin complexed with three L35 molecules"><img alt="2d5z: Crystal structure of T-state human hemoglobin complexed with three L35 molecules" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/51/PDB_2d5z_EBI.jpg/180px-PDB_2d5z_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/51/PDB_2d5z_EBI.jpg/270px-PDB_2d5z_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/51/PDB_2d5z_EBI.jpg/360px-PDB_2d5z_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2d5z</b>: Crystal structure of T-state human hemoglobin complexed with three L35 molecules</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2d60_EBI.jpg" class="mw-file-description" title="2d60: Crystal structure of deoxy human hemoglobin complexed with two L35 molecules"><img alt="2d60: Crystal structure of deoxy human hemoglobin complexed with two L35 molecules" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/PDB_2d60_EBI.jpg/180px-PDB_2d60_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/PDB_2d60_EBI.jpg/270px-PDB_2d60_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e5/PDB_2d60_EBI.jpg/360px-PDB_2d60_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2d60</b>: Crystal structure of deoxy human hemoglobin complexed with two L35 molecules</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2dn1_EBI.jpg" class="mw-file-description" title="2dn1: 1.25A resolution crystal structure of human hemoglobin in the oxy form"><img alt="2dn1: 1.25A resolution crystal structure of human hemoglobin in the oxy form" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0e/PDB_2dn1_EBI.jpg/180px-PDB_2dn1_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0e/PDB_2dn1_EBI.jpg/270px-PDB_2dn1_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0e/PDB_2dn1_EBI.jpg/360px-PDB_2dn1_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2dn1</b>: 1.25A resolution crystal structure of human hemoglobin in the oxy form</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2dn2_EBI.jpg" class="mw-file-description" title="2dn2: 1.25A resolution crystal structure of human hemoglobin in the deoxy form"><img alt="2dn2: 1.25A resolution crystal structure of human hemoglobin in the deoxy form" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/1e/PDB_2dn2_EBI.jpg/180px-PDB_2dn2_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/1e/PDB_2dn2_EBI.jpg/270px-PDB_2dn2_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/1e/PDB_2dn2_EBI.jpg/360px-PDB_2dn2_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2dn2</b>: 1.25A resolution crystal structure of human hemoglobin in the deoxy form</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2dn3_EBI.jpg" class="mw-file-description" title="2dn3: 1.25A resolution crystal structure of human hemoglobin in the carbonmonoxy form"><img alt="2dn3: 1.25A resolution crystal structure of human hemoglobin in the carbonmonoxy form" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_2dn3_EBI.jpg/180px-PDB_2dn3_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_2dn3_EBI.jpg/270px-PDB_2dn3_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/78/PDB_2dn3_EBI.jpg/360px-PDB_2dn3_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2dn3</b>: 1.25A resolution crystal structure of human hemoglobin in the carbonmonoxy form</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2h35_EBI.jpg" class="mw-file-description" title="2h35: Solution structure of Human normal adult hemoglobin"><img alt="2h35: Solution structure of Human normal adult hemoglobin" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/48/PDB_2h35_EBI.jpg/180px-PDB_2h35_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/48/PDB_2h35_EBI.jpg/270px-PDB_2h35_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/48/PDB_2h35_EBI.jpg/360px-PDB_2h35_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2h35</b>: Solution structure of Human normal adult hemoglobin</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hbc_EBI.jpg" class="mw-file-description" title="2hbc: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"><img alt="2hbc: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_2hbc_EBI.jpg/180px-PDB_2hbc_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_2hbc_EBI.jpg/270px-PDB_2hbc_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_2hbc_EBI.jpg/360px-PDB_2hbc_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hbc</b>: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hbd_EBI.jpg" class="mw-file-description" title="2hbd: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"><img alt="2hbd: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/PDB_2hbd_EBI.jpg/180px-PDB_2hbd_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/PDB_2hbd_EBI.jpg/270px-PDB_2hbd_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f3/PDB_2hbd_EBI.jpg/360px-PDB_2hbd_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hbd</b>: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hbe_EBI.jpg" class="mw-file-description" title="2hbe: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"><img alt="2hbe: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f9/PDB_2hbe_EBI.jpg/180px-PDB_2hbe_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f9/PDB_2hbe_EBI.jpg/270px-PDB_2hbe_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f9/PDB_2hbe_EBI.jpg/360px-PDB_2hbe_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hbe</b>: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hbf_EBI.jpg" class="mw-file-description" title="2hbf: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"><img alt="2hbf: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d1/PDB_2hbf_EBI.jpg/180px-PDB_2hbf_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d1/PDB_2hbf_EBI.jpg/270px-PDB_2hbf_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d1/PDB_2hbf_EBI.jpg/360px-PDB_2hbf_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hbf</b>: HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hbs_EBI.jpg" class="mw-file-description" title="2hbs: THE HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXYHEMOGLOBIN S"><img alt="2hbs: THE HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXYHEMOGLOBIN S" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_2hbs_EBI.jpg/180px-PDB_2hbs_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_2hbs_EBI.jpg/270px-PDB_2hbs_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a4/PDB_2hbs_EBI.jpg/360px-PDB_2hbs_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hbs</b>: THE HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXYHEMOGLOBIN S</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hco_EBI.jpg" class="mw-file-description" title="2hco: THE STRUCTURE OF HUMAN CARBONMONOXY HAEMOGLOBIN AT 2.7 ANGSTROMS RESOLUTION"><img alt="2hco: THE STRUCTURE OF HUMAN CARBONMONOXY HAEMOGLOBIN AT 2.7 ANGSTROMS RESOLUTION" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_2hco_EBI.jpg/180px-PDB_2hco_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_2hco_EBI.jpg/270px-PDB_2hco_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_2hco_EBI.jpg/360px-PDB_2hco_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hco</b>: THE STRUCTURE OF HUMAN CARBONMONOXY HAEMOGLOBIN AT 2.7 ANGSTROMS RESOLUTION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hhb_EBI.jpg" class="mw-file-description" title="2hhb: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION"><img alt="2hhb: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/PDB_2hhb_EBI.jpg/180px-PDB_2hhb_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/PDB_2hhb_EBI.jpg/270px-PDB_2hhb_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/aa/PDB_2hhb_EBI.jpg/360px-PDB_2hhb_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hhb</b>: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hhd_EBI.jpg" class="mw-file-description" title="2hhd: OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA-CHAINS IN HUMAN AND BOVINE HEMOGLOBIN"><img alt="2hhd: OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA-CHAINS IN HUMAN AND BOVINE HEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/PDB_2hhd_EBI.jpg/180px-PDB_2hhd_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/PDB_2hhd_EBI.jpg/270px-PDB_2hhd_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4e/PDB_2hhd_EBI.jpg/360px-PDB_2hhd_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hhd</b>: OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA-CHAINS IN HUMAN AND BOVINE HEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_2hhe_EBI.jpg" class="mw-file-description" title="2hhe: OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA CHAINS IN HUMAN AND BOVINE HEMOGLOBIN"><img alt="2hhe: OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA CHAINS IN HUMAN AND BOVINE HEMOGLOBIN" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_2hhe_EBI.jpg/180px-PDB_2hhe_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_2hhe_EBI.jpg/270px-PDB_2hhe_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/04/PDB_2hhe_EBI.jpg/360px-PDB_2hhe_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>2hhe</b>: OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA CHAINS IN HUMAN AND BOVINE HEMOGLOBIN</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_3hhb_EBI.jpg" class="mw-file-description" title="3hhb: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION"><img alt="3hhb: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_3hhb_EBI.jpg/180px-PDB_3hhb_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_3hhb_EBI.jpg/270px-PDB_3hhb_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/94/PDB_3hhb_EBI.jpg/360px-PDB_3hhb_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>3hhb</b>: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_4hhb_EBI.jpg" class="mw-file-description" title="4hhb: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION"><img alt="4hhb: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/PDB_4hhb_EBI.jpg/180px-PDB_4hhb_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/PDB_4hhb_EBI.jpg/270px-PDB_4hhb_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/PDB_4hhb_EBI.jpg/360px-PDB_4hhb_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>4hhb</b>: THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_6hbw_EBI.jpg" class="mw-file-description" title="6hbw: Crystal structure of deoxy-human hemoglobin beta6 glu->trp"><img alt="6hbw: Crystal structure of deoxy-human hemoglobin beta6 glu->trp" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_6hbw_EBI.jpg/180px-PDB_6hbw_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_6hbw_EBI.jpg/270px-PDB_6hbw_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_6hbw_EBI.jpg/360px-PDB_6hbw_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>6hbw</b>: Crystal structure of deoxy-human hemoglobin beta6 glu->trp</div> </li> </ul></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Proteins_that_contain_heme_(hemoproteins)" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Hemeproteins" title="Template:Hemeproteins"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Hemeproteins" title="Template talk:Hemeproteins"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Hemeproteins" title="Special:EditPage/Template:Hemeproteins"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Proteins_that_contain_heme_(hemoproteins)" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein" title="Protein">Proteins</a> that contain <a href="/wiki/Heme" title="Heme">heme</a> (<a href="/wiki/Hemoprotein" title="Hemoprotein">hemoproteins</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Globin" title="Globin">Globins</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Hemoglobin" title="Hemoglobin">Hemoglobin</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Subunits</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i>Alpha locus on <a href="/wiki/Chromosome_16" title="Chromosome 16">16</a>:</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>α</i> <ul><li><a href="/wiki/Hemoglobin_subunit_alpha" title="Hemoglobin subunit alpha">HBA1</a></li> <li><a href="/wiki/Hemoglobin,_alpha_2" title="Hemoglobin, alpha 2">HBA2</a></li> <li><a href="/wiki/HBAP1" title="HBAP1">pseudo</a></li></ul></li> <li><i>ζ</i> <ul><li><a href="/wiki/Hemoglobin_subunit_zeta" title="Hemoglobin subunit zeta">HBZ</a></li></ul></li> <li><i>θ</i> <ul><li><a href="/wiki/HBQ1" title="HBQ1">HBQ1</a></li></ul></li> <li><i>μ</i> <ul><li><a href="/wiki/Mu_hemoglobin" title="Mu hemoglobin">HBM</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Human_%CE%B2-globin_locus" title="Human β-globin locus">Beta locus</a> on <a href="/wiki/Chromosome_11" title="Chromosome 11">11</a>:</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>β</i> <ul><li><a class="mw-selflink selflink">HBB</a></li></ul></li> <li><i>δ</i> <ul><li><a href="/wiki/HBD" title="HBD">HBD</a></li></ul></li> <li><i>γ</i> <ul><li><a href="/wiki/HBG1" title="HBG1">HBG1</a></li> <li><a href="/wiki/HBG2" title="HBG2">HBG2</a></li></ul></li> <li><i>ε</i> <ul><li><a href="/wiki/HBE1" title="HBE1">HBE1</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tetrameric_protein" title="Tetrameric protein">Tetramers</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i>stages of <br />development:</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Embryonic</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Embryonic_hemoglobin" title="Embryonic hemoglobin">HbE Gower 1</a> (ζ<sub>2</sub>ε<sub>2</sub>)</li> <li><a href="/wiki/Embryonic_hemoglobin" title="Embryonic hemoglobin">HbE Gower 2</a> (α<sub>2</sub>ε<sub>2</sub>)</li> <li><a href="/wiki/Embryonic_hemoglobin" title="Embryonic hemoglobin">HbE Portland I</a> (ζ<sub>2</sub>γ<sub>2</sub>)</li> <li><a href="/wiki/Embryonic_hemoglobin" title="Embryonic hemoglobin">HbE Portland II</a> (ζ<sub>2</sub>β<sub>2</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Fetal</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Fetal_hemoglobin" title="Fetal hemoglobin">HbF/Fetal</a> (α<sub>2</sub>γ<sub>2</sub>)</li> <li><a href="/wiki/Hemoglobin_A" title="Hemoglobin A">HbA</a> (α<sub>2</sub>β<sub>2</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Adult</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Hemoglobin_A" title="Hemoglobin A">HbA</a> (α<sub>2</sub>β<sub>2</sub>)</li> <li><a href="/wiki/Hemoglobin_A2" title="Hemoglobin A2">HbA<sub>2</sub></a> (α<sub>2</sub>δ<sub>2</sub>)</li> <li><a href="/wiki/Fetal_hemoglobin" title="Fetal hemoglobin">HbF/Fetal</a> (α<sub>2</sub>γ<sub>2</sub>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i>pathology:</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Alpha-thalassemia" title="Alpha-thalassemia">HbH</a> (β<sub>4</sub>)</li> <li><a href="/wiki/Hemoglobin_Barts" title="Hemoglobin Barts">Barts</a> (γ<sub>4</sub>)</li> <li><a href="/wiki/HbD" class="mw-redirect" title="HbD">HbD</a> (α<sub>2</sub>β<sup>D</sup><sub>2</sub>)</li> <li><a href="/wiki/Sickle_cell_disease" title="Sickle cell disease">HbS</a> (α<sub>2</sub>β<sup>S</sup><sub>2</sub>)</li> <li><a href="/wiki/Hemoglobin_C" title="Hemoglobin C">HbC</a> (α<sub>2</sub>β<sup>C</sup><sub>2</sub>)</li> <li><a href="/wiki/Hemoglobin_E" title="Hemoglobin E">HbE</a> (α<sub>2</sub>β<sup>E</sup><sub>2</sub>)</li> <li><a href="/wiki/Hemoglobin_O" title="Hemoglobin O">HbO</a> (α<sub>2</sub>β<sup>O</sup><sub>2</sub>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Compounds</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Carboxyhemoglobin" title="Carboxyhemoglobin">Carboxyhemoglobin</a></li> <li><a href="/wiki/Carbaminohemoglobin" title="Carbaminohemoglobin">Carbaminohemoglobin</a></li> <li><a href="/wiki/Hemoglobin" title="Hemoglobin">Oxyhemoglobin</a>/<a href="/wiki/Deoxyhemoglobin" class="mw-redirect" title="Deoxyhemoglobin">Deoxyhemoglobin</a></li> <li><a href="/wiki/Sulfhemoglobinemia" title="Sulfhemoglobinemia">Sulfhemoglobin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other human</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Glycated_hemoglobin" title="Glycated hemoglobin">Glycated hemoglobin</a></li> <li><a href="/wiki/Methemoglobin" title="Methemoglobin">Methemoglobin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Nonhuman</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Erythrocruorin" title="Erythrocruorin">Chlorocruorin</a></li> <li><a href="/wiki/Erythrocruorin" title="Erythrocruorin">Erythrocruorin</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i>human:</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Myoglobin" title="Myoglobin">Myoglobin</a> <ul><li><a href="/wiki/Metmyoglobin" title="Metmyoglobin">Metmyoglobin</a></li></ul></li> <li><a href="/wiki/Neuroglobin" title="Neuroglobin">Neuroglobin</a></li> <li><a href="/wiki/Cytoglobin" title="Cytoglobin">Cytoglobin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i>plant:</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Leghemoglobin" title="Leghemoglobin">Leghemoglobin</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cytochrome" title="Cytochrome">Cytochrome</a> <ul><li><a href="/wiki/Cytochrome_b" title="Cytochrome b">Cytochrome b</a></li> <li><a href="/wiki/Cytochrome_P450" title="Cytochrome P450">Cytochrome P450</a></li></ul></li> <li><a href="/wiki/Methemalbumin" title="Methemalbumin">Methemalbumin</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><i>see also <a href="/wiki/Template:Disorders_of_globin_and_globulin_proteins" title="Template:Disorders of globin and globulin proteins">disorders of globin and globulin proteins</a></i></div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Retrieved from "<a dir="ltr" href="https://en.wikipedia.org/w/index.php?title=Hemoglobin_subunit_beta&oldid=1255061577">https://en.wikipedia.org/w/index.php?title=Hemoglobin_subunit_beta&oldid=1255061577</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Help:Category" title="Help:Category">Categories</a>: <ul><li><a href="/wiki/Category:Genes_on_human_chromosome_11" title="Category:Genes on human chromosome 11">Genes on human chromosome 11</a></li><li><a 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