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dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Patient-reported outcome questionnaire</div> <p>The <b>Ankylosing Spondylitis Quality of Life</b> (<b>ASQoL</b>) questionnaire is a <a href="/wiki/Patient-reported_outcome" title="Patient-reported outcome">patient-reported outcome</a> (PRO) measure which assesses the <a href="/wiki/Quality_of_life" title="Quality of life">quality of life</a> of patients with <a href="/wiki/Ankylosing_spondylitis" title="Ankylosing spondylitis">ankylosing spondylitis</a>.<sup id="cite_ref-DowardSp_1-0" class="reference"><a href="#cite_note-DowardSp-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> The ASQoL is based on the needs-based quality of life model.<sup id="cite_ref-Poster_2-0" class="reference"><a href="#cite_note-Poster-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> It is a self-administered questionnaire which contains 18 items<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> and takes up to four minutes to complete.<sup id="cite_ref-DowardSp_1-1" class="reference"><a href="#cite_note-DowardSp-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>Developed by Galen Research and published in 2003,<sup id="cite_ref-DowardSp_1-2" class="reference"><a href="#cite_note-DowardSp-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> the ASQoL has been used in clinical studies worldwide. The content for the measure was drawn from <a href="/wiki/Qualitative_research" title="Qualitative research">qualitative</a> interviews that were conducted with ankylosing spondylitis (AS) patients. The draft version of the ASQoL was created and then went through several stages of testing to ensure it had good face validity, content validity, reproducibility and construct validity.<sup id="cite_ref-DowardSp_1-3" class="reference"><a href="#cite_note-DowardSp-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Content">Content</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ankylosing_Spondylitis_Quality_of_Life&action=edit&section=1" title="Edit section: Content"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1251242444">.mw-parser-output .ambox{border:1px solid #a2a9b1;border-left:10px solid #36c;background-color:#fbfbfb;box-sizing:border-box}.mw-parser-output .ambox+link+.ambox,.mw-parser-output .ambox+link+style+.ambox,.mw-parser-output .ambox+link+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+style+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+link+.ambox{margin-top:-1px}html body.mediawiki .mw-parser-output .ambox.mbox-small-left{margin:4px 1em 4px 0;overflow:hidden;width:238px;border-collapse:collapse;font-size:88%;line-height:1.25em}.mw-parser-output .ambox-speedy{border-left:10px solid #b32424;background-color:#fee7e6}.mw-parser-output .ambox-delete{border-left:10px solid #b32424}.mw-parser-output .ambox-content{border-left:10px solid #f28500}.mw-parser-output .ambox-style{border-left:10px solid #fc3}.mw-parser-output .ambox-move{border-left:10px solid #9932cc}.mw-parser-output .ambox-protection{border-left:10px solid #a2a9b1}.mw-parser-output .ambox .mbox-text{border:none;padding:0.25em 0.5em;width:100%}.mw-parser-output .ambox .mbox-image{border:none;padding:2px 0 2px 0.5em;text-align:center}.mw-parser-output .ambox .mbox-imageright{border:none;padding:2px 0.5em 2px 0;text-align:center}.mw-parser-output .ambox .mbox-empty-cell{border:none;padding:0;width:1px}.mw-parser-output .ambox .mbox-image-div{width:52px}@media(min-width:720px){.mw-parser-output .ambox{margin:0 10%}}@media print{body.ns-0 .mw-parser-output .ambox{display:none!important}}</style><table class="box-Expand_section plainlinks metadata ambox mbox-small-left ambox-content" role="presentation"><tbody><tr><td class="mbox-image"><span typeof="mw:File"><a href="/wiki/File:Wiki_letter_w_cropped.svg" class="mw-file-description"><img alt="[icon]" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/1c/Wiki_letter_w_cropped.svg/20px-Wiki_letter_w_cropped.svg.png" decoding="async" width="20" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/1c/Wiki_letter_w_cropped.svg/30px-Wiki_letter_w_cropped.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/1c/Wiki_letter_w_cropped.svg/40px-Wiki_letter_w_cropped.svg.png 2x" data-file-width="44" data-file-height="31" /></a></span></td><td class="mbox-text"><div class="mbox-text-span">This section <b>needs expansion</b>. You can help by <a class="external text" href="https://en.wikipedia.org/w/index.php?title=Ankylosing_Spondylitis_Quality_of_Life&action=edit&section=">adding to it</a>. <span class="date-container"><i>(<span class="date">November 2013</span>)</i></span></div></td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Language_adaptations">Language adaptations</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ankylosing_Spondylitis_Quality_of_Life&action=edit&section=2" title="Edit section: Language adaptations"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The ASQoL was initially developed in UK English and Dutch, but to date a total of 37 language versions have been adapted. The language adaptations can be broken down into waves: </p> <table class="wikitable"> <tbody><tr> <th>Wave</th> <th>Language Adaptation </th></tr> <tr> <td>First Wave</td> <td>US English, Canadian French, Canadian English, French, German, Italian, Spanish and Swedish<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Second Wave</td> <td>Argentinian Spanish, Belgian Flemish, Belgian French, US Spanish, Czech, Hungarian, Mexican Spanish, Turkish, Polish, New Zealand English and Brazilian Portuguese.<sup id="cite_ref-Poster_2-1" class="reference"><a href="#cite_note-Poster-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td>Third Wave</td> <td>Bulgarian, Chilean Spanish, Greek, Croatian, Danish, Finnish, Swedish for Finland, Hebrew, Korean, Norwegian, Peruvian Spanish, Philippine Tagalog, Russian, Slovakian, UAE Arabic, Traditional Chinese-Taiwan, Simplified Chinese-China.<sup id="cite_ref-Poster_2-2" class="reference"><a href="#cite_note-Poster-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </td></tr> </tbody></table> <div class="mw-heading mw-heading2"><h2 id="Pharmaceutical_use">Pharmaceutical use</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ankylosing_Spondylitis_Quality_of_Life&action=edit&section=3" title="Edit section: Pharmaceutical use"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Pharmaceutical companies began utilizing the ASQoL to test the effectiveness of newly developed <a href="/wiki/TNF_inhibitor" title="TNF inhibitor">TNF inhibitors</a>, which aid in the treatment of ankylosing spondylitis.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> Abbott has utilized the ASQoL to evaluate the impact of <a href="/wiki/Adalimumab" title="Adalimumab">adalimumab</a><sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> and other organizations like <a href="/wiki/Wyeth" title="Wyeth">Wyeth</a> and the <a href="/wiki/Medical_Research_Council_(United_Kingdom)" title="Medical Research Council (United Kingdom)">Medical Research Council</a> have used it to evaluate the effect of <a href="/wiki/Etanercept" title="Etanercept">etanercept</a>.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Evaluation">Evaluation</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ankylosing_Spondylitis_Quality_of_Life&action=edit&section=4" title="Edit section: Evaluation"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Since the development of the ASQoL, several studies have been performed in order to evaluate and validate the measure. These studies include: </p> <ul><li>Validation studies for different language versions of the ASQoL which found good reliability and validity.<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ankylosing_Spondylitis_Quality_of_Life&action=edit&section=5" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-DowardSp-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-DowardSp_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-DowardSp_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-DowardSp_1-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-DowardSp_1-3"><sup><i><b>d</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFDowardSpoorenbergCookWhalley2003" class="citation journal cs1">Doward, L.C.; 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"Cross-cultural adaptation and validation of a Spanish version of a specific instrument to measure health-related quality of life in patients with ankylosing spondylitis". <i>Reumatologia Clinica</i>. <b>2</b> (2): 64–69. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS1699-258X%2806%2973024-8">10.1016/S1699-258X(06)73024-8</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21794306">21794306</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Reumatologia+Clinica&rft.atitle=Cross-cultural+adaptation+and+validation+of+a+Spanish+version+of+a+specific+instrument+to+measure+health-related+quality+of+life+in+patients+with+ankylosing+spondylitis&rft.volume=2&rft.issue=2&rft.pages=64-69&rft.date=2006&rft_id=info%3Adoi%2F10.1016%2FS1699-258X%2806%2973024-8&rft_id=info%3Apmid%2F21794306&rft.aulast=Ariza-Ariza&rft.aufirst=R.&rft.au=Hernandez-Cruz%2C+B.&rft.au=Lopez-Anteguera%2C+G&rft.au=Toyos%2C+F.J.&rft.au=Navarro-Sarabia%2C+F.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAnkylosing+Spondylitis+Quality+of+Life" class="Z3988"></span></span> </li> </ol></div></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Retrieved from "<a dir="ltr" href="https://en.wikipedia.org/w/index.php?title=Ankylosing_Spondylitis_Quality_of_Life&oldid=1187840654">https://en.wikipedia.org/w/index.php?title=Ankylosing_Spondylitis_Quality_of_Life&oldid=1187840654</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Help:Category" title="Help:Category">Categories</a>: <ul><li><a href="/wiki/Category:Ankylosing_spondylitis" title="Category:Ankylosing spondylitis">Ankylosing spondylitis</a></li><li><a href="/wiki/Category:Patient_reported_outcome_measures" title="Category:Patient reported outcome measures">Patient reported outcome measures</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Hidden categories: <ul><li><a href="/wiki/Category:Articles_with_short_description" title="Category:Articles with short description">Articles with short description</a></li><li><a href="/wiki/Category:Short_description_matches_Wikidata" title="Category:Short description matches Wikidata">Short description matches Wikidata</a></li><li><a href="/wiki/Category:Articles_to_be_expanded_from_November_2013" title="Category:Articles to be expanded from November 2013">Articles to be expanded from November 2013</a></li><li><a href="/wiki/Category:All_articles_to_be_expanded" title="Category:All articles to be expanded">All articles to be expanded</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> This page was last edited on 1 December 2023, at 19:22<span class="anonymous-show"> (UTC)</span>.</li> <li id="footer-info-copyright">Text is available under the <a href="/wiki/Wikipedia:Text_of_the_Creative_Commons_Attribution-ShareAlike_4.0_International_License" title="Wikipedia:Text of the Creative Commons Attribution-ShareAlike 4.0 International License">Creative Commons Attribution-ShareAlike 4.0 License</a>; additional terms may apply. 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