<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns="http://purl.org/rss/1.0/" xmlns:admin="http://webns.net/mvcb/"> <channel rdf:about="http://feeds.nature.com/nbt/rss/current"> <title>Nature Biotechnology</title> <description>Nature Biotechnology is a monthly journal publishing new concepts in biological technology of relevance to bioengineering, medicine, energy, agriculture, food and the environment. It has a magazine covering the commercial, political, ethical, legal and societal aspects of this research.</description> <link>http://feeds.nature.com/nbt/rss/current</link> <admin:generatorAgent rdf:resource="https://www.nature.com/"/> <admin:errorReportsTo rdf:resource="mailto:feedback@nature.com"/> <dc:publisher>Nature Publishing Group</dc:publisher> <dc:language>en</dc:language> <dc:rights>© 2025 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.</dc:rights> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:copyright>© 2025 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.</prism:copyright> <prism:rightsAgent>permissions@nature.com</prism:rightsAgent> <image rdf:resource="https://www.nature.com/uploads/product/nbt/rss.png"/> <items> <rdf:Seq> <rdf:li rdf:resource="https://www.nature.com/articles/s41587-025-02580-5"/> <rdf:li rdf:resource="https://www.nature.com/articles/s41587-025-02561-8"/> <rdf:li rdf:resource="https://www.nature.com/articles/s41587-025-02560-9"/> <rdf:li rdf:resource="https://www.nature.com/articles/s41587-024-02540-5"/> <rdf:li rdf:resource="https://www.nature.com/articles/s41587-025-02570-7"/> <rdf:li rdf:resource="https://www.nature.com/articles/s41587-025-02590-3"/> <rdf:li rdf:resource="https://www.nature.com/articles/s41587-025-02568-1"/> <rdf:li rdf:resource="https://www.nature.com/articles/s41587-024-02547-y"/> </rdf:Seq> </items> </channel> <image rdf:about="https://www.nature.com/uploads/product/nbt/rss.png"> <title>Nature Biotechnology</title> <url>https://www.nature.com/uploads/product/nbt/rss.png</url> <link>http://feeds.nature.com/nbt/rss/current</link> </image> <item rdf:about="https://www.nature.com/articles/s41587-025-02580-5"> <title><![CDATA[Covalently or non-covalently attached m⁷G cap enhances protein production from circular mRNA]]></title> <link>https://www.nature.com/articles/s41587-025-02580-5</link> <content:encoded> <![CDATA[<p>Nature Biotechnology, Published online: 19 February 2025; <a href="https://www.nature.com/articles/s41587-025-02580-5">doi:10.1038/s41587-025-02580-5</a></p>The mechanism of translation initiation in linear and circular mRNAs influences translation efficiency. Covalent attachment of an N7-methylguanosine (m7G) cap increases protein production from circular mRNAs in mice. Hybridization with capped endogenous RNAs also promotes protein production in cells, suggesting that this interaction might also occur between endogenous RNAs.]]></content:encoded> <dc:title><![CDATA[Covalently or non-covalently attached m⁷G cap enhances protein production from circular mRNA]]></dc:title> <dc:identifier>doi:10.1038/s41587-025-02580-5</dc:identifier> <dc:source>Nature Biotechnology, Published online: 2025-02-19; | doi:10.1038/s41587-025-02580-5</dc:source> <dc:date>2025-02-19</dc:date> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:doi>10.1038/s41587-025-02580-5</prism:doi> <prism:url>https://www.nature.com/articles/s41587-025-02580-5</prism:url> </item> <item rdf:about="https://www.nature.com/articles/s41587-025-02561-8"> <title><![CDATA[Internal cap-initiated translation for efficient protein production from circular mRNA]]></title> <link>https://www.nature.com/articles/s41587-025-02561-8</link> <content:encoded> <![CDATA[<p>Nature Biotechnology, Published online: 19 February 2025; <a href="https://www.nature.com/articles/s41587-025-02561-8">doi:10.1038/s41587-025-02561-8</a></p>Placement of an m7G cap internally on circular RNAs promotes their translation in vivo.]]></content:encoded> <dc:title><![CDATA[Internal cap-initiated translation for efficient protein production from circular mRNA]]></dc:title> <dc:creator>Kosuke Fukuchi</dc:creator><dc:creator>Yuko Nakashima</dc:creator><dc:creator>Naoko Abe</dc:creator><dc:creator>Seigo Kimura</dc:creator><dc:creator>Fumitaka Hashiya</dc:creator><dc:creator>Yuichi Shichino</dc:creator><dc:creator>Yiwei Liu</dc:creator><dc:creator>Ryoko Ogisu</dc:creator><dc:creator>Satomi Sugiyama</dc:creator><dc:creator>Daisuke Kawaguchi</dc:creator><dc:creator>Masahito Inagaki</dc:creator><dc:creator>Zheyu Meng</dc:creator><dc:creator>Shiryu Kajihara</dc:creator><dc:creator>Mizuki Tada</dc:creator><dc:creator>Satoshi Uchida</dc:creator><dc:creator>Ting-Ting Li</dc:creator><dc:creator>Ramkrishna Maity</dc:creator><dc:creator>Tairin Kawasaki</dc:creator><dc:creator>Yasuaki Kimura</dc:creator><dc:creator>Shintaro Iwasaki</dc:creator><dc:creator>Hiroshi Abe</dc:creator> <dc:identifier>doi:10.1038/s41587-025-02561-8</dc:identifier> <dc:source>Nature Biotechnology, Published online: 2025-02-19; | doi:10.1038/s41587-025-02561-8</dc:source> <dc:date>2025-02-19</dc:date> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:doi>10.1038/s41587-025-02561-8</prism:doi> <prism:url>https://www.nature.com/articles/s41587-025-02561-8</prism:url> </item> <item rdf:about="https://www.nature.com/articles/s41587-025-02560-9"> <title><![CDATA[A ‘CRISPR’ way to visualize RNA in live cells]]></title> <link>https://www.nature.com/articles/s41587-025-02560-9</link> <content:encoded> <![CDATA[<p>Nature Biotechnology, Published online: 18 February 2025; <a href="https://www.nature.com/articles/s41587-025-02560-9">doi:10.1038/s41587-025-02560-9</a></p>Visualizing RNA molecules in live cells remains a challenge, and existing methods require genetic manipulation or have limited resolution. Our study overcomes these limitations by using the programmable CRISPR–Csm tool to bind and track individual transcripts in their native state.]]></content:encoded> <dc:title><![CDATA[A ‘CRISPR’ way to visualize RNA in live cells]]></dc:title> <dc:identifier>doi:10.1038/s41587-025-02560-9</dc:identifier> <dc:source>Nature Biotechnology, Published online: 2025-02-18; | doi:10.1038/s41587-025-02560-9</dc:source> <dc:date>2025-02-18</dc:date> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:doi>10.1038/s41587-025-02560-9</prism:doi> <prism:url>https://www.nature.com/articles/s41587-025-02560-9</prism:url> </item> <item rdf:about="https://www.nature.com/articles/s41587-024-02540-5"> <title><![CDATA[Single-molecule live-cell RNA imaging with CRISPR–Csm]]></title> <link>https://www.nature.com/articles/s41587-024-02540-5</link> <content:encoded> <![CDATA[<p>Nature Biotechnology, Published online: 18 February 2025; <a href="https://www.nature.com/articles/s41587-024-02540-5">doi:10.1038/s41587-024-02540-5</a></p>Single-molecule live-cell fluorescence in situ hybridization uses an RNA-targeting CRISPR–Csm complex to image and track endogenous RNAs.]]></content:encoded> <dc:title><![CDATA[Single-molecule live-cell RNA imaging with CRISPR–Csm]]></dc:title> <dc:creator>Chenglong Xia</dc:creator><dc:creator>David Colognori</dc:creator><dc:creator>Xueyang Stephen Jiang</dc:creator><dc:creator>Ke Xu</dc:creator><dc:creator>Jennifer A. Doudna</dc:creator> <dc:identifier>doi:10.1038/s41587-024-02540-5</dc:identifier> <dc:source>Nature Biotechnology, Published online: 2025-02-18; | doi:10.1038/s41587-024-02540-5</dc:source> <dc:date>2025-02-18</dc:date> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:doi>10.1038/s41587-024-02540-5</prism:doi> <prism:url>https://www.nature.com/articles/s41587-024-02540-5</prism:url> </item> <item rdf:about="https://www.nature.com/articles/s41587-025-02570-7"> <title><![CDATA[Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage]]></title> <link>https://www.nature.com/articles/s41587-025-02570-7</link> <content:encoded> <![CDATA[<p>Nature Biotechnology, Published online: 18 February 2025; <a href="https://www.nature.com/articles/s41587-025-02570-7">doi:10.1038/s41587-025-02570-7</a></p>Biologics are delivered to the gut using phage that infects resident commensal bacteria.]]></content:encoded> <dc:title><![CDATA[Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage]]></dc:title> <dc:creator>Zachary R. Baker</dc:creator><dc:creator>Yao Zhang</dc:creator><dc:creator>Haiyan Zhang</dc:creator><dc:creator>Hollyn C. Franklin</dc:creator><dc:creator>Priscila B. S. Serpa</dc:creator><dc:creator>Teresa Southard</dc:creator><dc:creator>Liwu Li</dc:creator><dc:creator>Bryan B. Hsu</dc:creator> <dc:identifier>doi:10.1038/s41587-025-02570-7</dc:identifier> <dc:source>Nature Biotechnology, Published online: 2025-02-18; | doi:10.1038/s41587-025-02570-7</dc:source> <dc:date>2025-02-18</dc:date> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:doi>10.1038/s41587-025-02570-7</prism:doi> <prism:url>https://www.nature.com/articles/s41587-025-02570-7</prism:url> </item> <item rdf:about="https://www.nature.com/articles/s41587-025-02590-3"> <title><![CDATA[Vertex’s opioid-free drug for acute pain wins FDA approval]]></title> <link>https://www.nature.com/articles/s41587-025-02590-3</link> <content:encoded> <![CDATA[<p>Nature Biotechnology, Published online: 17 February 2025; <a href="https://www.nature.com/articles/s41587-025-02590-3">doi:10.1038/s41587-025-02590-3</a></p>Society, patients and clinicians welcome a much-needed non-opioid pain medication. Vertex’s first-in-class analgesic Journavx could soon be followed by a new generation of addiction-free pain drugs acting at NaV1.8 sodium channels.]]></content:encoded> <dc:title><![CDATA[Vertex’s opioid-free drug for acute pain wins FDA approval]]></dc:title> <dc:creator>Charlotte Harrison</dc:creator> <dc:identifier>doi:10.1038/s41587-025-02590-3</dc:identifier> <dc:source>Nature Biotechnology, Published online: 2025-02-17; | doi:10.1038/s41587-025-02590-3</dc:source> <dc:date>2025-02-17</dc:date> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:doi>10.1038/s41587-025-02590-3</prism:doi> <prism:url>https://www.nature.com/articles/s41587-025-02590-3</prism:url> </item> <item rdf:about="https://www.nature.com/articles/s41587-025-02568-1"> <title><![CDATA[The reverse transcriptase domain of prime editors contributes to DNA repair in mammalian cells]]></title> <link>https://www.nature.com/articles/s41587-025-02568-1</link> <content:encoded> <![CDATA[<p>Nature Biotechnology, Published online: 17 February 2025; <a href="https://www.nature.com/articles/s41587-025-02568-1">doi:10.1038/s41587-025-02568-1</a></p>DNA repair activity of reverse transcriptase may negatively affect prime editing precision.]]></content:encoded> <dc:title><![CDATA[The reverse transcriptase domain of prime editors contributes to DNA repair in mammalian cells]]></dc:title> <dc:creator>Chunwei Zheng</dc:creator><dc:creator>Gangming Zhang</dc:creator><dc:creator>Lilia J. Dean</dc:creator><dc:creator>Erik J. Sontheimer</dc:creator><dc:creator>Wen Xue</dc:creator> <dc:identifier>doi:10.1038/s41587-025-02568-1</dc:identifier> <dc:source>Nature Biotechnology, Published online: 2025-02-17; | doi:10.1038/s41587-025-02568-1</dc:source> <dc:date>2025-02-17</dc:date> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:doi>10.1038/s41587-025-02568-1</prism:doi> <prism:url>https://www.nature.com/articles/s41587-025-02568-1</prism:url> </item> <item rdf:about="https://www.nature.com/articles/s41587-024-02547-y"> <title><![CDATA[Antibodies]]></title> <link>https://www.nature.com/articles/s41587-024-02547-y</link> <content:encoded> <![CDATA[<p>Nature Biotechnology, Published online: 14 February 2025; <a href="https://www.nature.com/articles/s41587-024-02547-y">doi:10.1038/s41587-024-02547-y</a></p>Recent patents relating to antibody compositions and methods of use.]]></content:encoded> <dc:title><![CDATA[Antibodies]]></dc:title> <dc:identifier>doi:10.1038/s41587-024-02547-y</dc:identifier> <dc:source>Nature Biotechnology, Published online: 2025-02-14; | doi:10.1038/s41587-024-02547-y</dc:source> <dc:date>2025-02-14</dc:date> <prism:publicationName>Nature Biotechnology</prism:publicationName> <prism:doi>10.1038/s41587-024-02547-y</prism:doi> <prism:url>https://www.nature.com/articles/s41587-024-02547-y</prism:url> </item> </rdf:RDF>