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</div> </div> </div> </div> </header> <main class="main-content"> <article id="post-7279" class="post-7279 product type-product status-publish hentry product_category-cell-culture"> <div class="page-title-wrap intro-section hide"> <div class="row"> <h1 class="columns mb-0 entry-title">G-Rex</h1> </div> </div> <div class="entry-content"> <div class="st-lazy-load-bg bg-cover p-intro intro-section position-relative zIndex-2 " data-src='https://www.scaleready.com/wp-content/uploads/2021/08/Group-214.png'> <div class="row"> <div class="columns small-12"> <div class="h1"> <p>G-Rex® closed-system bioreactors:<br /> Predictable, scalable cell expansion</p> </div> <div class="single-link h4 small-text-24-32 smb-0 mt-30"> <a href="#manufacturer_items" target="" >Full Product Line-Up ></a> </div> </div> </div> </div> <div class="row"> <div class="columns small-12"> <div class="sr-main-content"> <div class="wpb-content-wrapper"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-227.png'> <div class="corner-image bottom-right"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/figure-cell-4.png" alt="figure-cell-4"> </div> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/403x663-G-Rex.png" alt="403×663 G-Rex"> </div> </div> </div> <div class="columns small-12 medium-6 content color-white "> <h2 class="title color-navy-blue mb-40">G-Rex scales cell therapies intelligently.</h2> <div class="text last-no-margin"><p>G-Rex is the only cell culture bioreactor equipped to meet current and future patient demand for immune cell therapies. G-Rex was designed for predictable, efficient, and scalable cell expansion. It enables parallel patient processing and can produce the large numbers of cells needed for cell-based therapeutics, from preclinical through commercial scale manufacturing.</p> <h3>Simplicity enables rapid scale up with consistent phenotypic profiles.</h3> <p>G-Rex is ushering in a new era of simplicity for cell therapy manufacturing. By giving cells unlimited and undisturbed access to nutrients and oxygen, G-Rex bioreactors eliminate media exchanges and the complex and expensive hardware required in integrated systems.</p> </div> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-239.png'> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 small-order-1 medium-order-2 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/ice.png" alt="Multiple G-Rex Bioreactors in Incubator"> </div> </div> </div> <div class="columns small-12 medium-6 content color-black small-order-2 medium-order-1"> <h2 class="title color-navy-blue mb-40">Greater cell throughput in a smaller footprint.</h2> <div class="text last-no-margin"></p> <div>Maximize the therapeutic potential of your cell therapy through efficient and practical scale out. With one G-Rex bioreactor per patient and a small footprint per bioreactor, you can serve a high volume of patients in parallel—potentially treating 10,000 patients a year in 8x less space than conventional bioreactors.</div> <p> </div> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-269.png'> <div class="corner-image bottom-left"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/figure-molecule.png" alt="figure-molecule"> </div> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Final_uncropped-00035.png" alt="Final_uncropped-00035"> </div> </div> </div> <div class="columns small-12 medium-6 content color-white "> <h2 class="title color-navy-blue mb-40">G-Rex minimizes process development risk by using your preclinical protocols in large scale manufacturing.</h2> <div class="text last-no-margin"><p>Linear and predictable cell expansion in G-Rex bioreactors means a streamlined path to the clinic. Using G-Rex, the preclinical protocol and cell quality you develop directly transfers up into a large-scale closed-system process. In doing so you eliminate unnecessary process changes that often plague scale-up into complex bioreactors.</p> </div> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div data-vc-full-width="true" data-vc-full-width-init="false" class="vc_row wpb_row vc_row-fluid bg-cover vc_custom_1631172403028 vc_row-has-fill"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"><div id="manufacturer_items" class="sr_full_width_content bg-cover st-lazy-load-bg p-bioreactor" > <div class="section-title-wrapper v-2 mb-40 position-relative zIndex-2"> <h2 class="title mb-40 smb-20 color-deep-blue">Bioreactor sizes from small scale research to commercial scale manufacturing.</h2> <div class="intro-text"> G-Rex cell culture bioreactors are offered with varying footprints and media fill volumes. The portfolio is designed to accommodate the diverse needs associated with cell therapy manufacturing, supporting small scale research protocols, RUO and open systems all the way through commercial scale manufacturing, GMP and closed-system. </div> </div> <div class="row position-relative zIndex-3 has-shadow"> <div class="columns small-12 medium-3 mb-30 g-box"> <div class="img-wrapper small-text-center position-relative"> <div class="revealator-zoomin rev-item"></div> <img class="st-lazy-load-bg zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/10/80660M_MWP-6-Well-Tall_catalog-nobackground.png" alt="G-Rex®6M Well Plate"> </div> <div class="matchHeight text-center mb-20"> <h5 class="small-text-26-36">G-Rex®6M Well Plate</h5> <div class="text-18-24 l-24 ff-pnsb">Yields 200-400x10<sup>6</sup><br /> cells/well</div> </div> <div class="text-16-21 matchHeight">Individual well specifications: 10cm² gas permeable membrane with a 100mL media capacity. Expand 5 million cells into between 200 to 400 million cells in about 10 days with NO medium exchange.</div> </div> <div class="columns small-12 medium-3 mb-30 g-box"> <div class="img-wrapper small-text-center position-relative"> <div class="revealator-zoomin rev-item"></div> <img class="st-lazy-load-bg zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/G-Rex10M-CSGen2-png-1024x1024-1.png" alt="G-Rex®10M Series"> </div> <div class="matchHeight text-center mb-20"> <h5 class="small-text-26-36">G-Rex®10M Series</h5> <div class="text-18-24 l-24 ff-pnsb">Yields 200-400x10<sup>6</sup><br /> cells/bioreactor</div> </div> <div class="text-16-21 matchHeight">10cm² membrane with 100 mL media capacity. Closed system with semi-automated liquid handling. Expand 5 million cells into between 200 to 400 million cells in about 10 days with NO medium exchange.</div> </div> <div class="columns small-12 medium-3 mb-30 g-box"> <div class="img-wrapper small-text-center position-relative"> <div class="revealator-zoomin rev-item"></div> <img class="st-lazy-load-bg zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/G-Rex100M-CSGen2-png-1024x1024-1.png" alt="G-Rex®100M Series"> </div> <div class="matchHeight text-center mb-20"> <h5 class="small-text-26-36">G-Rex®100M Series</h5> <div class="text-18-24 l-24 ff-pnsb">Yields 2-4x10<sup>9</sup><br /> cells/bioreactor</div> </div> <div class="text-16-21 matchHeight">100cm² gas permeable membrane surface area with 1000 mL fill volume. Closed system with semi-automated liquid handling. Expand 50 million cells into between 2 to 4 billion cells in about 10 days with NO medium exchange.</div> </div> <div class="columns small-12 medium-3 mb-30 g-box"> <div class="img-wrapper small-text-center position-relative"> <div class="revealator-zoomin rev-item"></div> <img class="st-lazy-load-bg zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/G-Rex500M-CSGen2-png-1024x1024-1.png" alt="G-Rex®500M Series"> </div> <div class="matchHeight text-center mb-20"> <h5 class="small-text-26-36">G-Rex®500M Series</h5> <div class="text-18-24 l-24 ff-pnsb">Yields 10-20x10<sup>9</sup><br /> cells/bioreactor</div> </div> <div class="text-16-21 matchHeight">500cm² gas permeable membrane surface area with 5000 mL media capacity. Closed system with semi-automated liquid handling. Expand 250 million cells into between 10 to 20 billion cells in about 10 days with NO medium exchange.</div> </div> </div> <div class="text-26-33 small-text-26-36 sl-42 ff-barlow fw-700 text-center mb-10 smb-0 color-deep-blue"> G-Rex Bioreactors are a product of Wilson Wolf </div> <div> <div class="text-26-33 small-text-26-36 sl-42 ff-barlow fw-700 text-center"> <a class="" href="https://www.scaleready.com/g-rex-product-ordering-information/" > View full product portfolio > </a> </div> </div> </div> <div class="row align-center"> <div class="column small-12 medium-12 large-9 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-smoke box-shadow-20 border-radius-32 l-box mb-50 smb-55 su"> <h3 class="color-deep-blue title small-text-36-42">How to order</h3> <div class="row"> <div class="columns smb-22">Contact us directly to place an order, request assistance in tracking a previous shipment, or to obtain a lot-specific CoC.</div> <div class="columns shrink small-full-width"> <div><span class="ff-pnsb color-deep-blue">Phone:</span> 651-628-9259</div> <div><span class="ff-pnsb color-deep-blue">Email:</span> info@scaleready.com</div> <div><span class="ff-pnsb color-deep-blue">Fax:</span> 651-628-9507</div> </div> </div> </div> </div> </div> <div class="row"> <div class="column"> <h2 class="color-deep-blue h3 small-text-36-42 title mb-40 smb-30">Testimonials</h2> <div class="position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-smoke box-shadow-20 border-radius-32 l-box mb-50 smb-55 color-deep-blue ff-pnsb paragraph-last-no-margin su"> <div>“The Cell Processing Lab has shown that the culture of Tumor Infiltrating Lymphocytes (TIL), Natural Killer (NK) cells and LCL cells when using G-Rex are superior to growth bags. G-Rex allows for cell growth at higher densities and therefore less media, growth factors, cytokine and serum additives are required.”</p> <p>— Clinical Center, National Institutes of Health</div> </div> </div> </div> </div> <h2 class="color-deep-blue h3 small-text-36-42 title mb-40 smb-30">Additional G-Rex Resources</h2> <div class="row medium-type"> <div class="columns small-12 medium-6 large-4 mb-50 smb-50 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-smoke box-shadow-20 border-radius-32 l-box small full-height su"> <h3 class="text-26-32 color-deep-blue title">G-Rex – Revolutionizing Cell Therapy Manufacturing</h3> <div class="text-18-24 mb-15 smb-40 text"> <div></div> In this video you will learn how G-Rex bioreactors solve the limitations of flask and bag-based cell therapy manufacturing. By providing cells with uninterrupted access to oxygen and nutrients, the G-Rex cell culture device is the only accessible cell expansion technology that linearly scales to meet the demands of cell therapy manufacturers. </div> <div class="flex-container align-right text-21-28 ff-pnsb"> <a target="_blank" href="https://youtu.be/tpuOklz60yQ">Watch Video</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-50 smb-50 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-smoke box-shadow-20 border-radius-32 l-box small full-height su"> <h3 class="text-26-32 color-deep-blue title">On Demand Symposium: Defining Intelligent Scale-up and Scale-out</h3> <div class="text-18-24 mb-15 smb-40 text"> <div>In this recorded symposium, cell therapy manufacturing leaders speak about defining and planning for intelligent commercial scale up and scale out. Recorded at ISCT 2021.</div> </div> <div class="flex-container align-right text-21-28 ff-pnsb"> <a target="_blank" href="https://www.youtube.com/watch?v=MJ1J52zFDsg&t=1324s">Watch Symposium</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-50 smb-50 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-smoke box-shadow-20 border-radius-32 l-box small full-height su"> <h3 class="text-26-32 color-deep-blue title">Determining Optimal Seeding Density for Human T Cell Expansion in G-Rex</h3> <div class="text-18-24 mb-15 smb-40 text"> This scientific poster investigates the kinetics of human T cell expansion in small scale G-Rex6M bioreactors using ScaleReady reagents. Data show the affect of seeding density on fold expansion, total cell yield, and phenotypic phenotypic composition of expanded T cells, including total and memory CD4<sup>+</sup> and CD8<sup>+</sup> cells. </div> <div class="flex-container align-right text-21-28 ff-pnsb"> <a target="_blank" href="https://www.scaleready.com/wp-content/uploads/2021/08/Determining-Optimal-Seeding-Density-for-Human-T-Cell-poster.pdf">View Poster</a> </div> </div> </div> </div> <div> <div class="ptb-110 padding-top-0"> <a class="button mb-0" href="https://www.scaleready.com/knowledge-hq/" target=""> View All Resources </a> </div> </div> </div></div></div></div><div class="vc_row-full-width vc_clearfix"></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"><div class="st-lazy-load-bg sr_full_width_content bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-269.png'> <div class="callout-container flex-container align-middle full-width ptb-60"> <div class="row position-relative zIndex-2"> <div class="columns small-12 medium-7 "> <h3 class="title color-white small-text-36-42 smb-35">See how G-Rex Bioreactors fit into the ScaleReady™ workflow.</h3> </div> <div class="columns small-12 medium-5 text-right"> <a class="button mb-0 mt-15" href="/scaleready-platform/workflow" > Explore the Workflow </a> </div> </div> </div> </div> </div></div></div></div> </div> </div> </div> </div> </div> <div> </div> </article> </main> <footer class="footer color-white"> <div class="row position-relative zIndex-2"> <div class="columns small-12"> <section id="custom_html-2" class="widget_text widget widget_custom_html"><div class="textwidget custom-html-widget"><div class="row align-middle footer-top"> <div class="columns"> <div class="f-logo"> <img src="/wp-content/uploads/2021/08/Logo-White.png" alt="ScaleReady"> </div> </div> <div class="columns shrink flex-container"> <div class="ff-barlow fw-500 text"> <div class="fw-700">General Inquiries:</div> <a href="mailto:info@scaleready.com">info@scaleready.com</a> </div> <div class="ff-barlow fw-500 text"> <div class="fw-700">Career Opportunities:</div> <a href="mailto:careers@scaleready.com">careers@scaleready.com</a> </div> </div> </div> <hr /></div></section><section id="custom_html-3" class="widget_text widget widget_custom_html"><div class="textwidget custom-html-widget"><div class="row align-middle footer-middle"> <div class="columns"> <a class="f-social" href="https://www.linkedin.com/company/wearescaleready" title="Visit ScaleReady on LinkedIn" target="_blank" rel="noopener"> <img src="/wp-content/uploads/2021/08/Linkedin-Logo.png" alt="LinkedIn"> </a> </div> <div class="columns shrink flex-container"> <div class="ff-barlow fw-700 text"><a href="/terms-of-use">Terms of Use</a></div> <div class="ff-barlow fw-700 text"><a href="/privacy-policy">Privacy Policy</a></div> </div> </div></div></section><section id="text-2" class="widget widget_text"> <div class="textwidget"><div class="text-18-24 copyright">© 2024 ScaleReady USA</div> </div> </section> </div> </div> </footer> </div>  <script type='text/javascript'> piAId = '976203'; piCId = ''; piHostname = 'go.scaleready.com'; (function() { function async_load(){ var s = document.createElement('script'); s.type = 'text/javascript'; s.src = ('https:' == document.location.protocol ? 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