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<!DOCTYPE html> <html lang="en" dir="ltr"> <head>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-P63WKM1TM1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-P63WKM1TM1'); </script>  <script type="text/javascript" > (function(m,e,t,r,i,k,a){m[i]=m[i]||function(){(m[i].a=m[i].a||[]).push(arguments)}; m[i].l=1*new Date(); for (var j = 0; j < document.scripts.length; j++) {if (document.scripts[j].src === r) { return; }} k=e.createElement(t),a=e.getElementsByTagName(t)[0],k.async=1,k.src=r,a.parentNode.insertBefore(k,a)}) (window, document, "script", "https://mc.yandex.ru/metrika/tag.js", "ym"); ym(55165297, "init", { clickmap:false, trackLinks:true, accurateTrackBounce:true, webvisor:false }); </script> <noscript><div><img src="https://mc.yandex.ru/watch/55165297" style="position:absolute; left:-9999px;" alt="" /></div></noscript>    <title>Search results for: Nikolai V. Tkachenko</title> <meta name="description" content="Search results for: Nikolai V. Tkachenko"> <meta name="keywords" content="Nikolai V. Tkachenko"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="Nikolai V. 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Tkachenko"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 22</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Nikolai V. Tkachenko</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">22</span> Femtochemistry of Iron(III) Carboxylates in Aqueous Solutions</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ivan%20P.%20Pozdnyakov">Ivan P. Pozdnyakov</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexey%20A.%20Melnikov"> Alexey A. Melnikov</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20V.%20Tkachenko"> Nikolai V. Tkachenko</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Photochemical reactions with participation of iron (III) carboxylates are important for environmental photochemistry and have a great potential of application in water purification (Advanced Oxidation Processes, photo-Fenton and Fenton-like processes). In spite of this information about excited states and primary intermediates in photochemistry of Fe(III) complexes with carboxylic acids is scarce. This talk presents and discusses the results of several recent authors' publications in a field of ultra fast spectroscopy of natural Fe(III) carboxylates. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carboxylates" title="carboxylates">carboxylates</a>, <a href="https://publications.waset.org/abstracts/search?q=iron%20complexes" title=" iron complexes"> iron complexes</a>, <a href="https://publications.waset.org/abstracts/search?q=photochemistry" title=" photochemistry"> photochemistry</a>, <a href="https://publications.waset.org/abstracts/search?q=radical%20complexes" title=" radical complexes"> radical complexes</a>, <a href="https://publications.waset.org/abstracts/search?q=ultrafast%20processes" title=" ultrafast processes"> ultrafast processes</a> </p> <a href="https://publications.waset.org/abstracts/26936/femtochemistry-of-ironiii-carboxylates-in-aqueous-solutions" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/26936.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">456</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">21</span> Developing Research Involving Different Species: Opportunities and Empirical Foundations</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20V.%20Varfolomeeva">A. V. Varfolomeeva</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20S.%20Tkachenko"> N. S. Tkachenko</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20G.%20Tishchenko"> A. G. Tishchenko</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The problem of violation of internal validity in studies of psychological structures is considered. The role of epistemological attitudes of researchers in the planning of research within the methodology of the system-evolutionary approach is assessed. Alternative programs of psychological research involving representatives of different biological species are presented. On the example of the results of two research series the variants of solving the problem are discussed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=epistemological%20attitudes" title="epistemological attitudes">epistemological attitudes</a>, <a href="https://publications.waset.org/abstracts/search?q=experimental%20design" title="experimental design">experimental design</a>, <a href="https://publications.waset.org/abstracts/search?q=validity" title="validity">validity</a>, <a href="https://publications.waset.org/abstracts/search?q=psychological%20structure" title="psychological structure">psychological structure</a>, <a href="https://publications.waset.org/abstracts/search?q=learning" title="learning">learning</a> </p> <a href="https://publications.waset.org/abstracts/143662/developing-research-involving-different-species-opportunities-and-empirical-foundations" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/143662.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">115</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">20</span> Forecasting Free Cash Flow of an Industrial Enterprise Using Fuzzy Set Tools</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elena%20Tkachenko">Elena Tkachenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Elena%20Rogova"> Elena Rogova</a>, <a href="https://publications.waset.org/abstracts/search?q=Daria%20Koval"> Daria Koval</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper examines the ways of cash flows forecasting in the dynamic external environment. The so-called new reality in economy lowers the predictability of the companies’ performance indicators due to the lack of long-term steady trends in external conditions of development and fast changes in the markets. The traditional methods based on the trend analysis lead to a very high error of approximation. The macroeconomic situation for the last 10 years is defined by continuous consequences of financial crisis and arising of another one. In these conditions, the instruments of forecasting on the basis of fuzzy sets show good results. The fuzzy sets based models turn out to lower the error of approximation to acceptable level and to provide the companies with reliable cash flows estimation that helps to reach the financial stability. In the paper, the applicability of the model of cash flows forecasting based on fuzzy logic was analyzed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cash%20flow" title="cash flow">cash flow</a>, <a href="https://publications.waset.org/abstracts/search?q=industrial%20enterprise" title=" industrial enterprise"> industrial enterprise</a>, <a href="https://publications.waset.org/abstracts/search?q=forecasting" title=" forecasting"> forecasting</a>, <a href="https://publications.waset.org/abstracts/search?q=fuzzy%20sets" title=" fuzzy sets"> fuzzy sets</a> </p> <a href="https://publications.waset.org/abstracts/95525/forecasting-free-cash-flow-of-an-industrial-enterprise-using-fuzzy-set-tools" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/95525.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">208</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">19</span> Commercialization of Technologies, Productivity and Problems of Technological Audit in the Russian Economy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=E.%20A.%20Tkachenko">E. A. Tkachenko</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20M.%20Rogova"> E. M. Rogova</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20S.%20Osipenko"> A. S. Osipenko</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The problems of technological development for the Russian Federation take on special significance in the context of modernization of the production base. The complexity of the position of the Russian economy is that it cannot be attributed fully to developing ones. Russia is a strong industrial power that has gone through the processes of destructive de-industrialization in the conditions of changing its economic and political structure. The need to find ways for re-industrialization is not a unique task for the economies of industrially developed countries. Under the influence of production outsourcing for 20 years, the industrial potential of leading economies of the world was regressed against the backdrop of the ascent of China, a new industrial giant. Therefore, methods, tools, and techniques utilized for industrial renaissance in EU may be used to achieve a technological leap in the Russian Federation, especially since the temporary gap of 5-7 years makes it possible to analyze best practices and use those technological transfer tools that have shown the greatest efficiency. In this article, methods of technological transfer are analyzed, the role of technological audit is justified, and factors are analyzed that influence the successful process of commercialization of technologies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=technological%20transfer" title="technological transfer">technological transfer</a>, <a href="https://publications.waset.org/abstracts/search?q=productivity" title=" productivity"> productivity</a>, <a href="https://publications.waset.org/abstracts/search?q=technological%20audit" title=" technological audit"> technological audit</a>, <a href="https://publications.waset.org/abstracts/search?q=commercialization%20of%20technologies" title=" commercialization of technologies"> commercialization of technologies</a> </p> <a href="https://publications.waset.org/abstracts/85326/commercialization-of-technologies-productivity-and-problems-of-technological-audit-in-the-russian-economy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85326.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">214</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18</span> Temperature Dependence of the Optoelectronic Properties of InAs(Sb)-Based LED Heterostructures</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Antonina%20Semakova">Antonina Semakova</a>, <a href="https://publications.waset.org/abstracts/search?q=Karim%20Mynbaev"> Karim Mynbaev</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Bazhenov"> Nikolai Bazhenov</a>, <a href="https://publications.waset.org/abstracts/search?q=Anton%20Chernyaev"> Anton Chernyaev</a>, <a href="https://publications.waset.org/abstracts/search?q=Sergei%20Kizhaev"> Sergei Kizhaev</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Stoyanov"> Nikolai Stoyanov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> At present, heterostructures are used for fabrication of almost all types of optoelectronic devices. Our research focuses on the optoelectronic properties of InAs(Sb) solid solutions that are widely used in fabrication of light emitting diodes (LEDs) operating in middle wavelength infrared range (MWIR). This spectral range (2-6 μm) is relevant for laser diode spectroscopy of gases and molecules, for systems for the detection of explosive substances, medical applications, and for environmental monitoring. The fabrication of MWIR LEDs that operate efficiently at room temperature is mainly hindered by the predominance of non-radiative Auger recombination of charge carriers over the process of radiative recombination, which makes practical application of LEDs difficult. However, non-radiative recombination can be partly suppressed in quantum-well structures. In this regard, studies of such structures are quite topical. In this work, electroluminescence (EL) of LED heterostructures based on InAs(Sb) epitaxial films with the molar fraction of InSb ranging from 0 to 0.09 and multi quantum-well (MQW) structures was studied in the temperature range 4.2-300 K. The growth of the heterostructures was performed by metal-organic chemical vapour deposition on InAs substrates. On top of the active layer, a wide-bandgap InAsSb(Ga,P) barrier was formed. At low temperatures (4.2-100 K) stimulated emission was observed. As the temperature increased, the emission became spontaneous. The transition from stimulated emission to spontaneous one occurred at different temperatures for structures with different InSb contents in the active region. The temperature-dependent carrier lifetime, limited by radiative recombination and the most probable Auger processes (for the materials under consideration, CHHS and CHCC), were calculated within the framework of the Kane model. The effect of various recombination processes on the carrier lifetime was studied, and the dominant role of Auger processes was established. For MQW structures quantization energies for electrons, light and heavy holes were calculated. A characteristic feature of the experimental EL spectra of these structures was the presence of peaks with energy different from that of calculated optical transitions between the first quantization levels for electrons and heavy holes. The obtained results showed strong effect of the specific electronic structure of InAsSb on the energy and intensity of optical transitions in nanostructures based on this material. For the structure with MQWs in the active layer, a very weak temperature dependence of EL peak was observed at high temperatures (>150 K), which makes it attractive for fabricating temperature-resistant gas sensors operating in the middle-infrared range. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Electroluminescence" title="Electroluminescence">Electroluminescence</a>, <a href="https://publications.waset.org/abstracts/search?q=InAsSb" title=" InAsSb"> InAsSb</a>, <a href="https://publications.waset.org/abstracts/search?q=light%20emitting%20diode" title=" light emitting diode"> light emitting diode</a>, <a href="https://publications.waset.org/abstracts/search?q=quantum%20wells" title=" quantum wells"> quantum wells</a> </p> <a href="https://publications.waset.org/abstracts/122314/temperature-dependence-of-the-optoelectronic-properties-of-inassb-based-led-heterostructures" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/122314.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">212</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> Evolution of Performance Measurement Methods in Conditions of Uncertainty: The Implementation of Fuzzy Sets in Performance Measurement</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=E.%20A.%20Tkachenko">E. A. Tkachenko</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20M.%20Rogova"> E. M. Rogova</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20V.%20Klimov"> V. V. Klimov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> One of the basic issues of development management is connected with performance measurement as a prerequisite for identifying the achievement of development objectives. The aim of our research is to develop an improved model of assessing a company’s development results. The model should take into account the cyclical nature of development and the high degree of uncertainty in dealing with numerous management tasks. Our hypotheses may be formulated as follows: Hypothesis 1. The cycle of a company’s development may be studied from the standpoint of a project cycle. To do that, methods and tools of project analysis are to be used. Hypothesis 2. The problem of the uncertainty when justifying managerial decisions within the framework of a company’s development cycle can be solved through the use of the mathematical apparatus of fuzzy logic. The reasoned justification of the validity of the hypotheses made is given in the suggested article. The fuzzy logic toolkit applies to the case of technology shift within an enterprise. It is proven that some restrictions in performance measurement that are incurred to conventional methods could be eliminated by implementation of the fuzzy logic apparatus in performance measurement models. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=logic" title="logic">logic</a>, <a href="https://publications.waset.org/abstracts/search?q=fuzzy%20sets" title=" fuzzy sets"> fuzzy sets</a>, <a href="https://publications.waset.org/abstracts/search?q=performance%20measurement" title=" performance measurement"> performance measurement</a>, <a href="https://publications.waset.org/abstracts/search?q=project%20analysis" title=" project analysis"> project analysis</a> </p> <a href="https://publications.waset.org/abstracts/40744/evolution-of-performance-measurement-methods-in-conditions-of-uncertainty-the-implementation-of-fuzzy-sets-in-performance-measurement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40744.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">381</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> Dependence of the Electro-Stimulation of Saccharomyces cerevisiae by Pulsed Electric Field at the Yeast Growth Phase</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jessy%20Mattar">Jessy Mattar</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamad%20Turk"> Mohamad Turk</a>, <a href="https://publications.waset.org/abstracts/search?q=Maurice%20Nonus"> Maurice Nonus</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Lebovka"> Nikolai Lebovka</a>, <a href="https://publications.waset.org/abstracts/search?q=Henri%20El%20Zakhem"> Henri El Zakhem</a>, <a href="https://publications.waset.org/abstracts/search?q=Eugene%20Vorobiev"> Eugene Vorobiev</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The effects of electro-stimulation of S. cerevisiae cells in colloidal suspension by Pulsed Electric Fields ‎‎(PEF) with electric field strength E = 20 – 2000 V.cm-1 and effective PEF treatment time tPEF = 10^−5 – 1 s were ‎investigated. The applied experimental procedure includes variations in the preliminary fermentation time and ‎electro-stimulation by PEF-treatment. Plate counting was performed.‎ At relatively high electric fields (E ≥ 1000 V.cm-1) and moderate PEF treatment time (tPEF > 100 µs), the ‎extraction of ionic components from yeast was observed by conductivity measurements, which can be related to ‎electroporation of cell membranes. Cell counting revealed a dependency of the colonies’ size on the time of ‎preliminary fermentation tf and the power consumption W, however no dependencies were noticeable by varying the initial yeast concentration in the treated suspensions.‎ <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=intensification" title="intensification">intensification</a>, <a href="https://publications.waset.org/abstracts/search?q=yeast" title=" yeast"> yeast</a>, <a href="https://publications.waset.org/abstracts/search?q=fermentation" title=" fermentation"> fermentation</a>, <a href="https://publications.waset.org/abstracts/search?q=electroporation" title=" electroporation"> electroporation</a>, <a href="https://publications.waset.org/abstracts/search?q=biotechnology" title=" biotechnology"> biotechnology</a> </p> <a href="https://publications.waset.org/abstracts/10470/dependence-of-the-electro-stimulation-of-saccharomyces-cerevisiae-by-pulsed-electric-field-at-the-yeast-growth-phase" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/10470.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">469</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Evolution of Approaches to Cost Calculation in the Conditions of the Modern Russian Economy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elena%20Tkachenko">Elena Tkachenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Vladimir%20Kokh"> Vladimir Kokh</a>, <a href="https://publications.waset.org/abstracts/search?q=Alina%20Osipenko"> Alina Osipenko</a>, <a href="https://publications.waset.org/abstracts/search?q=Vladislav%20Surkov"> Vladislav Surkov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The modern period of development of Russian economy is fraught with a number of problems related to limitations in the use of traditional planning and financial management tools. Restrictions in the use of foreign software when performing an order of the Russian Government, on the one hand, and sanctions limiting the support of the major ERP and MRP II systems in the Russian Federation, on the other hand, entail the necessity to appeal to the basics of developing budgeting and analysis systems for industrial enterprises. Thus, cost calculation theory becomes the theoretical foundation for the development of industrial cost management systems. Based on the foregoing, it would be fair to make an assumption that the development of a working managerial accounting model on an industrial enterprise using an automated enterprise resource management system should rest upon the concept of the inevitability of alterations of business processes. On the other hand, optimized business processes make the architecture of financial analytics more transparent and permit the use of all the benefits of data cubes. The metrics and indicator slices provide online assessment of the state of key business processes at a given moment of time, which improves the quality of managerial decisions considerably. Therefore, the bilateral sanctions situation boosted the development of corporate business analytics and took industrial companies to the next level of understanding of business processes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cost%20culculation" title="cost culculation">cost culculation</a>, <a href="https://publications.waset.org/abstracts/search?q=ERP" title=" ERP"> ERP</a>, <a href="https://publications.waset.org/abstracts/search?q=OLAP" title=" OLAP"> OLAP</a>, <a href="https://publications.waset.org/abstracts/search?q=modern%20Russian%20economy" title=" modern Russian economy"> modern Russian economy</a> </p> <a href="https://publications.waset.org/abstracts/106821/evolution-of-approaches-to-cost-calculation-in-the-conditions-of-the-modern-russian-economy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/106821.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">221</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Paying Less and Getting More: Evidence on the Effect of Corporate Purpose from Two Natural Field Experiments</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Brosch">Nikolai Brosch</a>, <a href="https://publications.waset.org/abstracts/search?q=Alwine%20Mohnen"> Alwine Mohnen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Academics and business leaders increasingly call for a (re)definition of a corporate purpose beyond profit-maximization to contribute to the welfare of society. This study investigates the effect of communicating such a pro-social corporate purpose on three employee-level outcomes that constitute major cost components for most organizations: workers reservation wage, work quality, and work misbehavior. To provide causal evidence, two natural field experiments were conducted with almost 2,000 workers recruited from different online labor marketplaces. Workers were randomly assigned to treatments manipulating whether or not they received information about the employer’s corporate purpose and subsequently performed a short, real-effort task for payment. The main findings in both experiments show that receiving information about an employer’s pro-social corporate purpose causes workers to accept lower wages (9% lower in the first experiment and 28% lower in the second experiment) for the same job. Workers that personally assess high importance to organizations having a pro-social purpose are most responsive. At the same time, sacrificing wage for a corporate purpose comes at no cost of quality and even decreases the likelihood of engaging in work misbehavior. In a broader context, the results provide some evidence that the (re)definition of corporate purpose in commercial organizations is not ultimately at odds with creating profits. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=corporate%20purpose" title="corporate purpose">corporate purpose</a>, <a href="https://publications.waset.org/abstracts/search?q=natural%20field%20experiment" title=" natural field experiment"> natural field experiment</a>, <a href="https://publications.waset.org/abstracts/search?q=reservation%20wage" title=" reservation wage"> reservation wage</a>, <a href="https://publications.waset.org/abstracts/search?q=work%20misbehavior" title=" work misbehavior"> work misbehavior</a>, <a href="https://publications.waset.org/abstracts/search?q=work%20quality" title=" work quality"> work quality</a> </p> <a href="https://publications.waset.org/abstracts/133629/paying-less-and-getting-more-evidence-on-the-effect-of-corporate-purpose-from-two-natural-field-experiments" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/133629.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">238</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Nietzsche's 'Will to Power' as a Potentially Irrational-Rational Psychopathology: How and Why Amor Fati May Prove to Be Its 'Horse Whisperer'</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20David%20Blaskow">Nikolai David Blaskow</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nietzsche's scholarship in the main has never quite resolved its deeply divided, at times self-contradictory responses to what Friedrich Nietzsche might have actually meant by his notion of the 'will to power'. Yet, in the context of the current global pandemic and climate change crisis, never has there been a more urgent need to investigate and resolve that contradiction. This paper argues for the 'will to power' as being a potentially irrational-rational psychopathology, one that can properly be understood only by means of Nietzsche's agonistic insights into another psychopathology—that of ressentiment. The argument also makes a case for the contention that amor fati (Nietzsche’s positive affirmation of life) may prove to be ressentiment's cure. In addition, as an integral part of the case’s methodology, the lens defined as the Mimetic and Scapegoat theory of Rene Girard (1923-2015) is brought to bear on resolving the contradiction. Ressentiment and Mimetic Theory will prove to be key players in the investigation, in as much as they expose the reasons for a modernity in crisis. The major finding of this study is that when the explanatory power of the two theories is applied, an understanding of the dynamics of the crisis in which we find ourselves emerges. The keys to that insight will include: (1) how these two psychopathologies closely resemble the contemporary neurologically defined 'borderline conditions' and their implications for culture (2) how identity politics stifle exemplary leadership, and so create toxic cultures (3) a critical assessment of Achille Mbembe's (2019) re-working of Frantz Fanon's 'ethics of the passerby' and its resonances with Nietzsche's amor fati. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=agon" title="agon">agon</a>, <a href="https://publications.waset.org/abstracts/search?q=amor%20fati" title=" amor fati"> amor fati</a>, <a href="https://publications.waset.org/abstracts/search?q=borderline%20conditions" title=" borderline conditions"> borderline conditions</a>, <a href="https://publications.waset.org/abstracts/search?q=ethics%20of%20the%20passer%20by" title=" ethics of the passer by"> ethics of the passer by</a>, <a href="https://publications.waset.org/abstracts/search?q=exemplary%20leadership" title=" exemplary leadership"> exemplary leadership</a>, <a href="https://publications.waset.org/abstracts/search?q=identity%20politics" title=" identity politics"> identity politics</a>, <a href="https://publications.waset.org/abstracts/search?q=mimesis" title=" mimesis"> mimesis</a>, <a href="https://publications.waset.org/abstracts/search?q=ressentiment" title=" ressentiment"> ressentiment</a>, <a href="https://publications.waset.org/abstracts/search?q=scapegoat%20mechanism" title=" scapegoat mechanism"> scapegoat mechanism</a> </p> <a href="https://publications.waset.org/abstracts/133526/nietzsches-will-to-power-as-a-potentially-irrational-rational-psychopathology-how-and-why-amor-fati-may-prove-to-be-its-horse-whisperer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/133526.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">252</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Inactivation Kinetics of DNA and RNA Viruses by Ozone-Air Mixture in a Flow Mixer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Nosik">Nikolai Nosik</a>, <a href="https://publications.waset.org/abstracts/search?q=Vladislav%20Podmasterjev"> Vladislav Podmasterjev</a>, <a href="https://publications.waset.org/abstracts/search?q=Nina%20Kondrashina"> Nina Kondrashina</a>, <a href="https://publications.waset.org/abstracts/search?q=Marina%20Chataeva"> Marina Chataeva</a>, <a href="https://publications.waset.org/abstracts/search?q=Olga%20Lobach"> Olga Lobach</a>, <a href="https://publications.waset.org/abstracts/search?q=Dmitry%20Noosik"> Dmitry Noosik</a>, <a href="https://publications.waset.org/abstracts/search?q=Sergei%20Razumovskii"> Sergei Razumovskii</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Virucidal activity of ozone is well known: dissolved in water it kill viruses very fast. The virucidal capacity of ozone in ozone-air mixture is less known. The goal of the study was to investigate the virucidal potentials of the ozone–air mixture and kinetics of virus inactivation. Materials and methods. Ozone (O3 ) was generated from oxygen with ozonizer ( 1.0 – 75.0 mg\l). The ozone concentration was determined by the spectrophotometric methods. Virus contaminated samples were placed into the flowing reactor. Viruses: poliovirus type 1, vaccine strain (Sabin) and adenovirus, type 5, were obtained from the State virus collection. Titrations of viruses were carried out in appropriate cell cultures. CxT value ( mg\l x min) was calculated. Results. Metallic, polycarbonic and fiber “Kevlar” samples were contaminated with virus, dried and treated with ozone-air mixture in the flowing reactor. Kinetics of poliovirus inactivation: in 15 min at 5.0 mg\l -2.0 lg TCID50 inhibition , in 15 min at 10 mg\l – 2.5 lg TCID50 , 4.0 lg TCID50 inactivation of poliovirus was achieved after 75min at ozone concentration 20.0mg\l (99.99%). ( CxT = 75, 150 and 1500 mg\l x min on all three types of surfaces). It was found that the inactivation of poliovirus was more effective when the virus contaminated samples were wet (in 15 min at 20mg\l inhibition of virus in dry samples was 2.0 TCID50 , in wet samples – 4.0 TCID50). Adenovirus was less resistant to ozone treatment then poliovirus: 4.0 lg TCID50 inhibition was observed after 30 min of the treatment with ozone at 20mg\l ( CxT mg\l x min = 300 for adenovirus as for poliovirus it was 1500). Conclusion. It was found that ozone-air mixture inactivates viruses at rather high concentrations (compared to the reported effect of ozone dissolved in water). Despite of that there is a difference in the resistance to ozone action between viruses – poliovirus is more resistant then adenovirus-ozone-air mixture can be used for disinfection of large rooms. The maintaining of the virus-contaminated surfaces in wet condition allow to decrease the ozone load for virus inactivation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adenovirus" title="adenovirus">adenovirus</a>, <a href="https://publications.waset.org/abstracts/search?q=disinfection" title=" disinfection"> disinfection</a>, <a href="https://publications.waset.org/abstracts/search?q=ozone" title=" ozone"> ozone</a>, <a href="https://publications.waset.org/abstracts/search?q=poliovirus" title=" poliovirus"> poliovirus</a> </p> <a href="https://publications.waset.org/abstracts/68910/inactivation-kinetics-of-dna-and-rna-viruses-by-ozone-air-mixture-in-a-flow-mixer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/68910.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">355</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> An Investigation of the Use of Visible Spectrophotometric Analysis of Lead in an Herbal Tea Supplement</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Salve%20Alessandria%20Alcantara">Salve Alessandria Alcantara</a>, <a href="https://publications.waset.org/abstracts/search?q=John%20Armand%20E.%20Aquino"> John Armand E. Aquino</a>, <a href="https://publications.waset.org/abstracts/search?q=Ma.%20Veronica%20Aranda"> Ma. Veronica Aranda</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikki%20Francine%20Balde"> Nikki Francine Balde</a>, <a href="https://publications.waset.org/abstracts/search?q=Angeli%20Therese%20F.%20Cruz"> Angeli Therese F. Cruz</a>, <a href="https://publications.waset.org/abstracts/search?q=Elise%20Danielle%20Garcia"> Elise Danielle Garcia</a>, <a href="https://publications.waset.org/abstracts/search?q=Antonie%20Kyna%20Lim"> Antonie Kyna Lim</a>, <a href="https://publications.waset.org/abstracts/search?q=Divina%20Gracia%20Lucero"> Divina Gracia Lucero</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Thadeus%20Mappatao"> Nikolai Thadeus Mappatao</a>, <a href="https://publications.waset.org/abstracts/search?q=Maylan%20N.%20Ocat"> Maylan N. Ocat</a>, <a href="https://publications.waset.org/abstracts/search?q=Jamille%20Dyanne%20L.%20Pajarillo"> Jamille Dyanne L. Pajarillo</a>, <a href="https://publications.waset.org/abstracts/search?q=Jane%20Mierial%20A.%20Pesigan"> Jane Mierial A. Pesigan</a>, <a href="https://publications.waset.org/abstracts/search?q=Grace%20Kristin%20Viva"> Grace Kristin Viva</a>, <a href="https://publications.waset.org/abstracts/search?q=Jasmine%20Arielle%20C.%20Yap"> Jasmine Arielle C. Yap</a>, <a href="https://publications.waset.org/abstracts/search?q=Kathleen%20Michelle%20T.%20Yu"> Kathleen Michelle T. Yu</a>, <a href="https://publications.waset.org/abstracts/search?q=Joanna%20J.%20Orejola"> Joanna J. Orejola</a>, <a href="https://publications.waset.org/abstracts/search?q=Joanna%20V.%20Toralba"> Joanna V. Toralba </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Lead is a neurotoxic metallic element that is slowly accumulated in bones and tissues especially if present in products taken in a regular basis such as herbal tea supplements. Although sensitive analytical instruments are already available, the USP limit test for lead is still widely used. However, because of its serious shortcomings, Lang Lang and his colleagues developed a spectrophotometric method for determination of lead in all types of samples. This method was the one adapted in this study. The actual procedure performed was divided into three parts: digestion, extraction and analysis. For digestion, HNO3 and CH3COOH were used. Afterwards, masking agents, 0.003% and 0.001% dithizone in CHCl3 were added and used for the extraction. For the analysis, standard addition method and colorimetry were performed. This was done in triplicates under two conditions. The 1st condition, using 25µg/mL of standard, resulted to very low absorbances with an r2 of 0.551. This led to the use of a higher concentration, 1mg/mL, for condition 2. Precipitation of lead cyanide was observed and the absorbance readings were relatively higher but between 0.15-0.25, resulting to a very low r2 of 0.429. LOQ and LOD were not computed due to the limitations of the Milton-Roy Spectrophotometer. The method performed has a shorter digestion time, and used less but more accessible reagents. However, the optimum ratio of dithizone-lead complex must be observed in order to obtain reliable results while exploring other concentration of standards. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=herbal%20tea%20supplement" title="herbal tea supplement">herbal tea supplement</a>, <a href="https://publications.waset.org/abstracts/search?q=lead-dithizone%20complex" title=" lead-dithizone complex"> lead-dithizone complex</a>, <a href="https://publications.waset.org/abstracts/search?q=standard%20addition" title=" standard addition"> standard addition</a>, <a href="https://publications.waset.org/abstracts/search?q=visible%20spectroscopy" title=" visible spectroscopy"> visible spectroscopy</a> </p> <a href="https://publications.waset.org/abstracts/10463/an-investigation-of-the-use-of-visible-spectrophotometric-analysis-of-lead-in-an-herbal-tea-supplement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/10463.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">387</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Experimental Architectural Pedagogy: Discipline Space and Its Role in the Modern Teaching Identity</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Matthew%20Armitt">Matthew Armitt</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The revolutionary school of architectural teaching – VKhUTEAMAS (1923-1926) was a new approach for a new society bringing architectural education to the masses and masses to the growing industrial production. The school's pedagogical contribution of the 1920s made it an important school of the modernist movement, engaging pedagogy as a mode of experimentation. The teachers and students saw design education not just as a process of knowledge transfer but as a vehicle for design innovation developing an approach without precedent. This process of teaching and learning served as a vehicle for venturing into the unknown through a discipline of architectural teaching called “Space” developed by the Soviet architect Nikolai Ladovskii (1881-1941). The creation of “Space” was paramount not only for its innovative pedagogy but also as an experimental laboratory for developing new architectural language. This paper discusses whether the historical teaching of “Space” can function in the construction of the modern teaching identity today to promote value, richness, quality, and diversity inherent in architectural design education. The history of “Space” teaching remains unknown within academic circles and separate from the current architectural teaching debate. Using VKhUTEMAS and the teaching of “Space” as a pedagogical lens and drawing upon research carried out in the Russian Federation, America, Canada, Germany, and the UK, this paper discusses how historically different models of teaching and learning can intersect through examining historical based educational research by exploring different design studio initiatives; pedagogical methodologies; teaching and learning theories and problem-based projects. There are strong arguments and desire for pedagogical change and this paper will promote new historical and educational research to widen the current academic debate by exposing new approaches to architectural teaching today. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=VKhUTEMAS" title="VKhUTEMAS">VKhUTEMAS</a>, <a href="https://publications.waset.org/abstracts/search?q=discipline%20space" title=" discipline space"> discipline space</a>, <a href="https://publications.waset.org/abstracts/search?q=modernist%20pedagogy" title=" modernist pedagogy"> modernist pedagogy</a>, <a href="https://publications.waset.org/abstracts/search?q=teaching%20identity" title=" teaching identity "> teaching identity </a> </p> <a href="https://publications.waset.org/abstracts/128941/experimental-architectural-pedagogy-discipline-space-and-its-role-in-the-modern-teaching-identity" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/128941.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">127</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Numerical Simulation of Aeroelastic Influence Exerted by Kinematic and Geometrical Parameters on Oscillations' Frequencies and Phase Shift Angles in a Simulated Compressor of Gas Transmittal Unit</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Liliia%20N.%20Butymova">Liliia N. Butymova</a>, <a href="https://publications.waset.org/abstracts/search?q=Vladimir%20Y.%20Modorsky"> Vladimir Y. Modorsky</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20A.%20Shevelev"> Nikolai A. Shevelev</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Prediction of vibration processes in gas transmittal units (GTU) is an urgent problem. Despite numerous scientific publications on the problem of vibrations in general, there are not enough works concerning FSI-modeling interaction processes between several deformable blades in gas-dynamic flow. Since it is very difficult to solve the problem in full scope, with all factors considered, a unidirectional dynamic coupled 1FSI model is suggested for use at the first stage, which would include, from symmetry considerations, two blades, which might be considered as the first stage of solving more general bidirectional problem. ANSYS CFX programmed multi-processor was chosen as a numerical computation tool. The problem was solved on PNRPU high-capacity computer complex. At the first stage of the study, blades were believed oscillating with the same frequency, although oscillation phases could be equal and could be different. At that non-stationary gas-dynamic forces distribution over the blades surfaces is calculated in run of simulation experiment. Oscillations in the “gas — structure” dynamic system are assumed to increase if the resultant of these gas-dynamic forces is in-phase with blade oscillation, and phase shift (φ=0). Provided these oscillation occur with phase shift, then oscillations might increase or decrease, depending on the phase shift value. The most important results are as follows: the angle of phase shift in inter-blade oscillation and the gas-dynamic force depends on the flow velocity, the specific inter-blade gap, and the shaft rotation speed; a phase shift in oscillation of adjacent blades does not always correspond to phase shift of gas-dynamic forces affecting the blades. Thus, it was discovered, that asynchronous oscillation of blades might cause either attenuation or intensification of oscillation. It was revealed that clocking effect might depend not only on the mutual circumferential displacement of blade rows and the gap between the blades, but also on the blade dynamic deformation nature. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aeroelasticity" title="aeroelasticity">aeroelasticity</a>, <a href="https://publications.waset.org/abstracts/search?q=ANSYS%20CFX" title=" ANSYS CFX"> ANSYS CFX</a>, <a href="https://publications.waset.org/abstracts/search?q=oscillation" title=" oscillation"> oscillation</a>, <a href="https://publications.waset.org/abstracts/search?q=phase%20shift" title=" phase shift"> phase shift</a>, <a href="https://publications.waset.org/abstracts/search?q=clocking%20effect" title=" clocking effect"> clocking effect</a>, <a href="https://publications.waset.org/abstracts/search?q=vibrations" title=" vibrations"> vibrations</a> </p> <a href="https://publications.waset.org/abstracts/45119/numerical-simulation-of-aeroelastic-influence-exerted-by-kinematic-and-geometrical-parameters-on-oscillations-frequencies-and-phase-shift-angles-in-a-simulated-compressor-of-gas-transmittal-unit" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45119.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">269</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Intrastromal Donor Limbal Segments Implantation as a Surgical Treatment of Progressive Keratoconus: Clinical and Functional Results</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mikhail%20Panes">Mikhail Panes</a>, <a href="https://publications.waset.org/abstracts/search?q=Sergei%20Pozniak"> Sergei Pozniak</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Pozniak"> Nikolai Pozniak</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: To evaluate the effectiveness of intrastromal donor limbal segments implantation for treatment of progressive keratoconus considering on main characteristics of corneal endothelial cells. Setting: Outpatient ophthalmic clinic. Methods: Twenty patients (20 eyes) with progressive keratoconus II-III of Amsler classification were recruited. The worst eye was treated with the transplantation of donor limbal segments in the recipient corneal stroma, while the fellow eye was left untreated as a control of functional and morphological changes. Furthermore, twenty patients (20 eyes) without progressive keratoconus was used as a control of corneal endothelial cells changes. All patients underwent a complete ocular examination including uncorrected and corrected distance visual acuity (UDVA, CDVA), slit lamp examination fundus examination, corneal topography and pachymetry, auto-keratometry, Anterior Segment Optical Coherence Tomography and Corneal Endothelial Specular Microscopy. Results: After two years, statistically significant improvement in the UDVA and CDVA (on the average on two lines for UDVA and three-four lines for CDVA) were noted. Besides corneal astigmatism decreased from 5.82 ± 2.64 to 1.92 ± 1.4 D. Moreover there were no statistically significant differences in the changes of mean spherical equivalent, keratometry and pachymetry indicators. It should be noted that after two years there were no significant differences in the changes of the number and form of corneal endothelial cells. It can be regarded as a process stabilization. In untreated control eyes, there was a general trend towards worsening of UDVA, CDVA and corneal thickness, while corneal astigmatism was increased. Conclusion: Intrastromal donor segments implantation is a safe technique for keratoconus treatment. Intrastromal donor segments implantation is an efficient procedure to stabilize and improve progressive keratoconus. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=corneal%20endothelial%20cells" title="corneal endothelial cells">corneal endothelial cells</a>, <a href="https://publications.waset.org/abstracts/search?q=intrastromal%20donor%20limbal%20segments" title=" intrastromal donor limbal segments"> intrastromal donor limbal segments</a>, <a href="https://publications.waset.org/abstracts/search?q=progressive%20keratoconus" title=" progressive keratoconus"> progressive keratoconus</a>, <a href="https://publications.waset.org/abstracts/search?q=surgical%20treatment%20of%20keratoconus" title=" surgical treatment of keratoconus"> surgical treatment of keratoconus</a> </p> <a href="https://publications.waset.org/abstracts/50386/intrastromal-donor-limbal-segments-implantation-as-a-surgical-treatment-of-progressive-keratoconus-clinical-and-functional-results" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/50386.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">281</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> A Tool Tuning Approximation Method: Exploration of the System Dynamics and Its Impact on Milling Stability When Amending Tool Stickout</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Bertelsen">Nikolai Bertelsen</a>, <a href="https://publications.waset.org/abstracts/search?q=Robert%20A.%20Alphinas"> Robert A. Alphinas</a>, <a href="https://publications.waset.org/abstracts/search?q=Klaus%20B.%20Orskov"> Klaus B. Orskov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The shortest possible tool stickout has been the traditional go-to approach with expectations of increased stability and productivity. However, experimental studies at Danish Advanced Manufacturing Research Center (DAMRC) have proven that for some tool stickout lengths, there exist local productivity optimums when utilizing the Stability Lobe Diagrams for chatter avoidance. This contradicts with traditional logic and the best practices taught to machinists. This paper explores the vibrational characteristics and behaviour of a milling system over the tool stickout length. The experimental investigation has been conducted by tap testing multiple endmills where the tool stickout length has been varied. For each length, the modal parameters have been recorded and mapped to visualize behavioural tendencies. Furthermore, the paper explores the correlation between the modal parameters and the Stability Lobe Diagram to outline the influence and importance of each parameter in a multi-mode system. The insights are conceptualized into a tool tuning approximation solution. It builds on an almost linear change in the natural frequencies when amending tool stickout, which results in changed positions of the Chatter-free Stability Lobes. Furthermore, if the natural frequency of two modes become too close, it will onset of the dynamic absorber effect phenomenon. This phenomenon increases the critical stable depth of cut, allowing for a more stable milling process. Validation tests on the tool tuning approximation solution have shown varying success of the solution. This outlines the need for further research on the boundary conditions of the solution to understand at which conditions the tool tuning approximation solution is applicable. If the conditions get defined, the conceptualized tool tuning approximation solution outlines an approach for quick and roughly approximating tool stickouts with the potential for increased stiffness and optimized productivity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=milling" title="milling">milling</a>, <a href="https://publications.waset.org/abstracts/search?q=modal%20parameters" title=" modal parameters"> modal parameters</a>, <a href="https://publications.waset.org/abstracts/search?q=stability%20lobes" title=" stability lobes"> stability lobes</a>, <a href="https://publications.waset.org/abstracts/search?q=tap%20testing" title=" tap testing"> tap testing</a>, <a href="https://publications.waset.org/abstracts/search?q=tool%20tuning" title=" tool tuning"> tool tuning</a> </p> <a href="https://publications.waset.org/abstracts/128047/a-tool-tuning-approximation-method-exploration-of-the-system-dynamics-and-its-impact-on-milling-stability-when-amending-tool-stickout" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/128047.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">157</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> NanoSat MO Framework: Simulating a Constellation of Satellites with Docker Containers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=C%C3%A9sar%20Coelho">César Coelho</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Wiegand"> Nikolai Wiegand</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The advancement of nanosatellite technology has opened new avenues for cost-effective and faster space missions. The NanoSat MO Framework (NMF) from the European Space Agency (ESA) provides a modular and simpler approach to the development of flight software and operations of small satellites. This paper presents a methodology using the NMF together with Docker for simulating constellations of satellites. By leveraging Docker containers, the software environment of individual satellites can be easily replicated within a simulated constellation. This containerized approach allows for rapid deployment, isolation, and management of satellite instances, facilitating comprehensive testing and development in a controlled setting. By integrating the NMF lightweight simulator in the container, a comprehensive simulation environment was achieved. A significant advantage of using Docker containers is their inherent scalability, enabling the simulation of hundreds or even thousands of satellites with minimal overhead. Docker's lightweight nature ensures efficient resource utilization, allowing for deployment on a single host or across a cluster of hosts. This capability is crucial for large-scale simulations, such as in the case of mega-constellations, where multiple traditional virtual machines would be impractical due to their higher resource demands. This ability for easy horizontal scaling based on the number of simulated satellites provides tremendous flexibility to different mission scenarios. Our results demonstrate that leveraging Docker containers with the NanoSat MO Framework provides a highly efficient and scalable solution for simulating satellite constellations, offering not only significant benefits in terms of resource utilization and operational flexibility but also enabling testing and validation of ground software for constellations. The findings underscore the importance of taking advantage of already existing technologies in computer science to create new solutions for future satellite constellations in space. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=containerization" title="containerization">containerization</a>, <a href="https://publications.waset.org/abstracts/search?q=docker%20containers" title=" docker containers"> docker containers</a>, <a href="https://publications.waset.org/abstracts/search?q=NanoSat%20MO%20framework" title=" NanoSat MO framework"> NanoSat MO framework</a>, <a href="https://publications.waset.org/abstracts/search?q=satellite%20constellation%20simulation" title=" satellite constellation simulation"> satellite constellation simulation</a>, <a href="https://publications.waset.org/abstracts/search?q=scalability" title=" scalability"> scalability</a>, <a href="https://publications.waset.org/abstracts/search?q=small%20satellites" title=" small satellites"> small satellites</a> </p> <a href="https://publications.waset.org/abstracts/186837/nanosat-mo-framework-simulating-a-constellation-of-satellites-with-docker-containers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/186837.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">49</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Resonant Fluorescence in a Two-Level Atom and the Terahertz Gap</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20N.%20Bogolubov">Nikolai N. Bogolubov</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrey%20V.%20Soldatov"> Andrey V. Soldatov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Terahertz radiation occupies a range of frequencies somewhere from 100 GHz to approximately 10 THz, just between microwaves and infrared waves. This range of frequencies holds promise for many useful applications in experimental applied physics and technology. At the same time, reliable, simple techniques for generation, amplification, and modulation of electromagnetic radiation in this range are far from been developed enough to meet the requirements of its practical usage, especially in comparison to the level of technological abilities already achieved for other domains of the electromagnetic spectrum. This situation of relative underdevelopment of this potentially very important range of electromagnetic spectrum is known under the name of the 'terahertz gap.' Among other things, technological progress in the terahertz area has been impeded by the lack of compact, low energy consumption, easily controlled and continuously radiating terahertz radiation sources. Therefore, development of new techniques serving this purpose as well as various devices based on them is of obvious necessity. No doubt, it would be highly advantageous to employ the simplest of suitable physical systems as major critical components in these techniques and devices. The purpose of the present research was to show by means of conventional methods of non-equilibrium statistical mechanics and the theory of open quantum systems, that a thoroughly studied two-level quantum system, also known as an one-electron two-level 'atom', being driven by external classical monochromatic high-frequency (e.g. laser) field, can radiate continuously at much lower (e.g. terahertz) frequency in the fluorescent regime if the transition dipole moment operator of this 'atom' possesses permanent non-equal diagonal matrix elements. This assumption contradicts conventional assumption routinely made in quantum optics that only the non-diagonal matrix elements persist. The conventional assumption is pertinent to natural atoms and molecules and stems from the property of spatial inversion symmetry of their eigenstates. At the same time, such an assumption is justified no more in regard to artificially manufactured quantum systems of reduced dimensionality, such as, for example, quantum dots, which are often nicknamed 'artificial atoms' due to striking similarity of their optical properties to those ones of the real atoms. Possible ways to experimental observation and practical implementation of the predicted effect are discussed too. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=terahertz%20gap" title="terahertz gap">terahertz gap</a>, <a href="https://publications.waset.org/abstracts/search?q=two-level%20atom" title=" two-level atom"> two-level atom</a>, <a href="https://publications.waset.org/abstracts/search?q=resonant%20fluorescence" title=" resonant fluorescence"> resonant fluorescence</a>, <a href="https://publications.waset.org/abstracts/search?q=quantum%20dot" title=" quantum dot"> quantum dot</a>, <a href="https://publications.waset.org/abstracts/search?q=resonant%20fluorescence" title=" resonant fluorescence"> resonant fluorescence</a>, <a href="https://publications.waset.org/abstracts/search?q=two-level%20atom" title=" two-level atom"> two-level atom</a> </p> <a href="https://publications.waset.org/abstracts/70294/resonant-fluorescence-in-a-two-level-atom-and-the-terahertz-gap" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70294.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">271</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Anti-Gravity to Neo-Concretism: The Epodic Spaces of Non-Objective Art</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alexandra%20Kennedy">Alexandra Kennedy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Making use of the notion of ‘epodic spaces’ this paper presents a reconsideration of non-objective art practices, proposing alternatives to established materialist, formalist, process-based conceptualist approaches to such work. In his Neo-Concrete Manifesto (1959) Ferreira Gullar (1930-2016) sought to create a distinction between various forms of non-objective art. He distinguished the ‘geometric’ arts of neoplasticism, constructivism, and suprematism – which he described as ‘dangerously acute rationalism’ – from other non-objective practices. These alternatives, he proposed, have an expressive potential lacking in the former and this formed the basis for their categorisation as neo-concrete. Gullar prioritized the phenomenological over the rational, with an emphasis on the role of the spectator (a key concept of minimalism). Gullar highlighted the central role of sensual experience, colour and the poetic in such work. In the early twentieth century, Russian Cosmism – an esoteric philosophical movement – was highly influential on Russian avant-garde artists and can account for suprematist artists’ interest in, and approach to, planar geometry and four-dimensional space as demonstrated in the abstract paintings of Kasimir Malevich (1879-1935). Nikolai Fyodorov (1823-1903) promoted the idea of anti-gravity and cosmic space as the field for artistic activity. The artist and writer Kuzma Petrov-Vodkin (1878-1939) wrote on the concept of Euclidean space, the overcoming of such rational conceptions of space and the breaking free from the gravitational field and the earth’s sphere. These imaginary spaces, which also invoke a bodily experience, present a poetic dimension to the work of the suprematists. It is a dimension that arguably aligns more with Gullar’s formulation of his neo-concrete rather than that of his alignment of Suprematism with rationalism. While found in experiments with planar geometry, the interest in forms suggestive of an experience of breaking free–both physically from the earth and conceptually from rational, mathematical space (in a pre-occupation with non-Euclidean space and anti-geometry) and in their engagement with the spatial properties of colour, Suprematism presents itself as imaginatively epodic. The paper discusses both historical and contemporary non-objective practices in this context, drawing attention to the manner in which the category of the non-objective is used to categorise art works which are, arguably, qualitatively different. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anti-gravity" title="anti-gravity">anti-gravity</a>, <a href="https://publications.waset.org/abstracts/search?q=neo-concrete" title=" neo-concrete"> neo-concrete</a>, <a href="https://publications.waset.org/abstracts/search?q=non-Euclidian%20geometry" title=" non-Euclidian geometry"> non-Euclidian geometry</a>, <a href="https://publications.waset.org/abstracts/search?q=non-objective%20painting" title=" non-objective painting"> non-objective painting</a> </p> <a href="https://publications.waset.org/abstracts/82452/anti-gravity-to-neo-concretism-the-epodic-spaces-of-non-objective-art" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/82452.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">178</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Phase Synchronization of Skin Blood Flow Oscillations under Deep Controlled Breathing in Human</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Arina%20V.%20Tankanag">Arina V. Tankanag</a>, <a href="https://publications.waset.org/abstracts/search?q=Gennady%20V.%20Krasnikov"> Gennady V. Krasnikov</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20K.%20Chemeris"> Nikolai K. Chemeris</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The development of respiration-dependent oscillations in the peripheral blood flow may occur by at least two mechanisms. The first mechanism is related to the change of venous pressure due to mechanical activity of lungs. This phenomenon is known as ‘respiratory pump’ and is one of the mechanisms of venous return of blood from the peripheral vessels to the heart. The second mechanism is related to the vasomotor reflexes controlled by the respiratory modulation of the activity of centers of the vegetative nervous system. Early high phase synchronization of respiration-dependent blood flow oscillations of left and right forearm skin in healthy volunteers at rest was shown. The aim of the work was to study the effect of deep controlled breathing on the phase synchronization of skin blood flow oscillations. 29 normotensive non-smoking young women (18-25 years old) of the normal constitution without diagnosed pathologies of skin, cardiovascular and respiratory systems participated in the study. For each of the participants six recording sessions were carried out: first, at the spontaneous breathing rate; and the next five, in the regimes of controlled breathing with fixed breathing depth and different rates of enforced breathing regime. The following rates of controlled breathing regime were used: 0.25, 0.16, 0.10, 0.07 and 0.05 Hz. The breathing depth amounted to 40% of the maximal chest excursion. Blood perfusion was registered by laser flowmeter LAKK-02 (LAZMA, Russia) with two identical channels (wavelength 0.63 µm; emission power, 0.5 mW). The first probe was fastened to the palmar surface of the distal phalanx of left forefinger; the second probe was attached to the external surface of the left forearm near the wrist joint. These skin zones were chosen as zones with different dominant mechanisms of vascular tonus regulation. The degree of phase synchronization of the registered signals was estimated from the value of the wavelet phase coherence. The duration of all recording was 5 min. The sampling frequency of the signals was 16 Hz. The increasing of synchronization of the respiratory-dependent skin blood flow oscillations for all controlled breathing regimes was obtained. Since the formation of respiration-dependent oscillations in the peripheral blood flow is mainly caused by the respiratory modulation of system blood pressure, the observed effects are most likely dependent on the breathing depth. It should be noted that with spontaneous breathing depth does not exceed 15% of the maximal chest excursion, while in the present study the breathing depth was 40%. Therefore it has been suggested that the observed significant increase of the phase synchronization of blood flow oscillations in our conditions is primarily due to an increase of breathing depth. This is due to the enhancement of both potential mechanisms of respiratory oscillation generation: venous pressure and sympathetic modulation of vascular tone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=deep%20controlled%20breathing" title="deep controlled breathing">deep controlled breathing</a>, <a href="https://publications.waset.org/abstracts/search?q=peripheral%20blood%20flow%20oscillations" title=" peripheral blood flow oscillations"> peripheral blood flow oscillations</a>, <a href="https://publications.waset.org/abstracts/search?q=phase%20synchronization" title=" phase synchronization"> phase synchronization</a>, <a href="https://publications.waset.org/abstracts/search?q=wavelet%20phase%20coherence" title=" wavelet phase coherence"> wavelet phase coherence</a> </p> <a href="https://publications.waset.org/abstracts/98130/phase-synchronization-of-skin-blood-flow-oscillations-under-deep-controlled-breathing-in-human" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98130.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">213</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Precursor Synthesis of Carbon Materials with Different Aggregates Morphologies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20A.%20Khlebnikov">Nikolai A. Khlebnikov</a>, <a href="https://publications.waset.org/abstracts/search?q=Vladimir%20N.%20Krasilnikov"> Vladimir N. Krasilnikov</a>, <a href="https://publications.waset.org/abstracts/search?q=Evgenii%20V.%20Polyakov"> Evgenii V. Polyakov</a>, <a href="https://publications.waset.org/abstracts/search?q=Anastasia%20A.%20Maltceva"> Anastasia A. Maltceva</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Carbon materials with advanced surfaces are widely used both in modern industry and in environmental protection. The physical-chemical nature of these materials is determined by the morphology of primary atomic and molecular carbon structures, which are the basis for synthesizing the following materials: zero-dimensional (fullerenes), one-dimensional (fiber, tubes), two-dimensional (graphene) carbon nanostructures, three-dimensional (multi-layer graphene, graphite, foams) with unique physical-chemical and functional properties. Experience shows that the microscopic morphological level is the basis for the creation of the next mesoscopic morphological level. The dependence of the morphology on the chemical way and process prehistory (crystallization, colloids formation, liquid crystal state and other) is the peculiarity of the last called level. These factors determine the consumer properties of carbon materials, such as specific surface area, porosity, chemical resistance in corrosive environments, catalytic and adsorption activities. Based on the developed ideology of thin precursor synthesis, the authors discuss one of the approaches of the porosity control of carbon-containing materials with a given aggregates morphology. The low-temperature thermolysis of precursors in a gas environment of a given composition is the basis of the above-mentioned idea. The processes of carbothermic precursor synthesis of two different compounds: tungsten carbide WC:nC and zinc oxide ZnO:nC containing an impurity phase in the form of free carbon were selected as subjects of the research. In the first case, the transition metal (tungsten) forming carbides was the object of the synthesis. In the second case, there was selected zinc that does not form carbides. The synthesis of both kinds of transition metals compounds was conducted by the method of precursor carbothermic synthesis from the organic solution. ZnO:nC composites were obtained by thermolysis of succinate Zn(OO(CH2)2OO), formate glycolate Zn(HCOO)(OCH2CH2O)1/2, glycerolate Zn(OCH2CHOCH2OH), and tartrate Zn(OOCCH(OH)CH(OH)COO). WC:nC composite was synthesized from ammonium paratungstate and glycerol. In all cases, carbon structures that are specific for diamond- like carbon forms appeared on the surface of WC and ZnO particles after the heat treatment. Tungsten carbide and zinc oxide were removed from the composites by selective chemical dissolution preserving the amorphous carbon phase. This work presents the results of investigating WC:nC and ZnO:nC composites and carbon nanopowders with tubular, tape, plate and onion morphologies of aggregates that are separated by chemical dissolution of WC and ZnO from the composites by the following methods: SEM, TEM, XPA, Raman spectroscopy, and BET. The connection between the carbon morphology under the conditions of synthesis and chemical nature of the precursor and the possibility of regulation of the morphology with the specific surface area up to 1700-2000 m2/g of carbon-structured materials are discussed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbon%20morphology" title="carbon morphology">carbon morphology</a>, <a href="https://publications.waset.org/abstracts/search?q=composite%20materials" title=" composite materials"> composite materials</a>, <a href="https://publications.waset.org/abstracts/search?q=precursor%20synthesis" title=" precursor synthesis"> precursor synthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=tungsten%20carbide" title=" tungsten carbide"> tungsten carbide</a>, <a href="https://publications.waset.org/abstracts/search?q=zinc%20oxide" title=" zinc oxide"> zinc oxide</a> </p> <a href="https://publications.waset.org/abstracts/32660/precursor-synthesis-of-carbon-materials-with-different-aggregates-morphologies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/32660.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">335</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Analysis of Potential Associations of Single Nucleotide Polymorphisms in Patients with Schizophrenia Spectrum Disorders</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tatiana%20Butkova">Tatiana Butkova</a>, <a href="https://publications.waset.org/abstracts/search?q=Nikolai%20Kibrik"> Nikolai Kibrik</a>, <a href="https://publications.waset.org/abstracts/search?q=Kristina%20Malsagova"> Kristina Malsagova</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexander%20Izotov"> Alexander Izotov</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexander%20Stepanov"> Alexander Stepanov</a>, <a href="https://publications.waset.org/abstracts/search?q=Anna%20Kaysheva"> Anna Kaysheva</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Relevance. The genetic risk of developing schizophrenia is determined by two factors: single nucleotide polymorphisms and gene copy number variations. The search for serological markers for early diagnosis of schizophrenia is driven by the fact that the first five years of the disease are accompanied by significant biological, psychological, and social changes. It is during this period that pathological processes are most amenable to correction. The aim of this study was to analyze single nucleotide polymorphisms (SNPs) that are hypothesized to potentially influence the onset and development of the endogenous process. Materials and Methods It was analyzed 73 single nucleotide polymorphism variants. The study included 48 patients undergoing inpatient treatment at "Psychiatric Clinical Hospital No. 1" in Moscow, comprising 23 females and 25 males. Inclusion criteria: - Patients aged 18 and above. - Diagnosis according to ICD-10: F20.0, F20.2, F20.8, F21.8, F25.1, F25.2. - Voluntary informed consent from patients. Exclusion criteria included: - The presence of concurrent somatic or neurological pathology, neuroinfections, epilepsy, organic central nervous system damage of any etiology, and regular use of medication. - Substance abuse and alcohol dependence. - Women who were pregnant or breastfeeding. Clinical and psychopathological assessment was complemented by psychometric evaluation using the PANSS scale at the beginning and end of treatment. The duration of observation during therapy was 4-6 weeks. Total DNA extraction was performed using QIAamp DNA. Blood samples were processed on Illumina HiScan and genotyped for 652,297 markers on the Infinium Global Chips Screening Array-24v2.0 using the IMPUTE2 program with parameters Ne=20,000 and k=90. Additional filtration was performed based on INFO>0.5 and genotype probability>0.5. Quality control of the obtained DNA was conducted using agarose gel electrophoresis, with each tested sample having a volume of 100 µL. Results. It was observed that several SNPs exhibited gender dependence. We identified groups of single nucleotide polymorphisms with a membership of 80% or more in either the female or male gender. These SNPs included rs2661319, rs2842030, rs4606, rs11868035, rs518147, rs5993883, and rs6269.Another noteworthy finding was the limited combination of SNPs sufficient to manifest clinical symptoms leading to hospitalization. Among all 48 patients, each of whom was analyzed for deviations in 73 SNPs, it was discovered that the combination of involved SNPs in the manifestation of pronounced clinical symptoms of schizophrenia was 19±3 out of 73 possible. In study, the frequency of occurrence of single nucleotide polymorphisms also varied. The most frequently observed SNPs were rs4849127 (in 90% of cases), rs1150226 (86%), rs1414334 (75%), rs10170310 (73%), rs2857657, and rs4436578 (71%). Conclusion. Thus, the results of this study provide additional evidence that these genes may be associated with the development of schizophrenia spectrum disorders. However, it's impossible cannot rule out the hypothesis that these polymorphisms may be in linkage disequilibrium with other functionally significant polymorphisms that may actually be involved in schizophrenia spectrum disorders. It has been shown that missense SNPs by themselves are likely not causative of the disease but are in strong linkage disequilibrium with non-functional SNPs that may indeed contribute to disease predisposition. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=gene%20polymorphisms" title="gene polymorphisms">gene polymorphisms</a>, <a href="https://publications.waset.org/abstracts/search?q=genotyping" title=" genotyping"> genotyping</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20nucleotide%20polymorphisms" title=" single nucleotide polymorphisms"> single nucleotide polymorphisms</a>, <a href="https://publications.waset.org/abstracts/search?q=schizophrenia." title=" schizophrenia."> schizophrenia.</a> </p> <a href="https://publications.waset.org/abstracts/174190/analysis-of-potential-associations-of-single-nucleotide-polymorphisms-in-patients-with-schizophrenia-spectrum-disorders" class="btn btn-primary 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