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Other protein target families | IUPHAR/BPS Guide to PHARMACOLOGY
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CONTENT START ==================== --> <div class="grid_12"> <!-- ==================== GRID 16 START ==================== --> <!-- --> <!-- ==================== GRID 16 START ==================== --> <div class="grid_16 alpha"> <a name="top"></a> <h4>Other protein targets</h4> <div class="contentboxfullhelp"> <div class="textright"> <p></p> <div style="text-align:right;"> <button class="button_gtoimmupdb_off" onClick='window.location.href="http://www.guidetoimmunopharmacology.org/GRAC/ReceptorFamiliesForward?type=OTHER&CGTP=false"; return false;'>GtoImmuPdb View OFF</button> <button onClick="expandTree('family_tree');return false;">Expand all nodes</button> <button onClick="collapseTree('family_tree'); return false;">Collapse all nodes</button> </div> <ul class="mktree" id ="family_tree"><li class="liOpen" ID="node864"><span class="tree_root_node">Other protein targets</span><span class="cgtp"> C</span><ul style="margin-bottom:0px;"><li class="liOpen" ID="node1021"><a id="link1021" href="FamilyDisplayForward?familyId=1021">Abscisic acid receptor complex</a></li><li class="liOpen" ID="node106"><a id="link106" href="FamilyDisplayForward?familyId=106">Adiponectin receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node982">Anti-infective targets<span class="cgtp"> C</span> <a href="FamilyDisplayForward?familyId=982&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node970">Antimalarial targets <a href="FamilyDisplayForward?familyId=970&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node1050"><a id="link1050" href="FamilyDisplayForward?familyId=1050">Aminoacyl-tRNA synthetases</a></li><li ID="node1059"><a id="link1059" href="FamilyDisplayForward?familyId=1059">Chromatin modifying enzymes (<i>Plasmodium</i> spp.)</a></li><li ID="node1053"><a id="link1053" href="FamilyDisplayForward?familyId=1053">Coenzyme A synthesis pathway enzymes</a></li><li ID="node1056"><a id="link1056" href="FamilyDisplayForward?familyId=1056">Cyclic nucleotide turnover/signalling (<i>Plasmodium spp.</i>)</a></li><li ID="node1051"><a id="link1051" href="FamilyDisplayForward?familyId=1051">Folate biosynthesis enzymes</a></li><li ID="node1052"><a id="link1052" href="FamilyDisplayForward?familyId=1052">Haemoglobin degradation pathway enzymes</a></li><li ID="node1055"><a id="link1055" href="FamilyDisplayForward?familyId=1055">Isoprenoid biosynthesis enzymes </a></li><li ID="node1054"><a id="link1054" href="FamilyDisplayForward?familyId=1054">Kinases (<i>Plasmodium</i> spp.)</a></li><li ID="node1060"><a id="link1060" href="FamilyDisplayForward?familyId=1060">Nucleoside synthesis and metabolism (<i>Plasmodium</i> spp.)</a></li><li ID="node1065"><a id="link1065" href="FamilyDisplayForward?familyId=1065">Mitochondrial function/Mitochondrial electron flow</a></li><li ID="node1061"><a id="link1061" href="FamilyDisplayForward?familyId=1061">Other antimalarial targets</a></li><li ID="node1063"><a id="link1063" href="FamilyDisplayForward?familyId=1063">Peptidases and proteinases (<i>Plasmodium</i> spp.)</a></li><li ID="node1057"><a id="link1057" href="FamilyDisplayForward?familyId=1057">Ribosomal factors (<i>Plasmodium</i> spp.)</a></li><li ID="node1064"><a id="link1064" href="FamilyDisplayForward?familyId=1064">Transporters (<i>Plasmodium</i> spp.)</a></li></ul></li><li ID="node1033">Viral protein targets<ul style="margin-bottom:0px;"><li ID="node1034"><a id="link1034" href="FamilyDisplayForward?familyId=1034">Coronavirus (CoV) proteins</a><span class="cgtp"> C</span></li><li ID="node1035"><a id="link1035" href="FamilyDisplayForward?familyId=1035">Other viral proteins</a></li></ul></li><li ID="node1074"><a id="link1074" href="FamilyDisplayForward?familyId=1074">Bacterial protein targets</a><span class="cgtp"> C</span></li></ul></li><li class="liOpen" ID="node971"><a id="link971" href="FamilyDisplayForward?familyId=971">Aryl hydrocarbon receptor</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node1073"><a id="link1073" href="FamilyDisplayForward?familyId=1073">Autophagy receptors</a></li><li class="liOpen" ID="node1081"><a id="link1081" href="FamilyDisplayForward?familyId=1081">β-catenin destruction complex proteins</a></li><li class="liOpen" ID="node910"><a id="link910" href="FamilyDisplayForward?familyId=910">B-cell lymphoma 2 (Bcl-2) protein family</a></li><li class="liOpen" ID="node866">Bromodomain-containing proteins <a href="FamilyDisplayForward?familyId=866&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node884">Enzymatic bromodomain-containing proteins<span class="cgtp"> C</span><ul style="margin-bottom:0px;"><li ID="node558"><a id="link558" href="FamilyDisplayForward?familyId=558">Bromodomain kinase (BRDK) family</a></li><li ID="node626"><a id="link626" href="FamilyDisplayForward?familyId=626">TAF1 family</a></li><li ID="node631"><a id="link631" href="FamilyDisplayForward?familyId=631">TIF1 family</a></li></ul></li><li ID="node867"><a id="link867" href="FamilyDisplayForward?familyId=867">Non-enzymatic BRD containing proteins</a><span class="cgtp"> C</span></li></ul></li><li class="liOpen" ID="node966"><a id="link966" href="FamilyDisplayForward?familyId=966">Butyrophilin and butyrophilin-like proteins</a></li><li class="liOpen" ID="node852"><a id="link852" href="FamilyDisplayForward?familyId=852">CD molecules</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node997">Chaperone proteins<ul style="margin-bottom:0px;"><li ID="node998"><a id="link998" href="FamilyDisplayForward?familyId=998">Lipid binding chaperones</a></li></ul></li><li class="liOpen" ID="node986"><a id="link986" href="FamilyDisplayForward?familyId=986">Chitinase-like proteins</a></li><li class="liOpen" ID="node916"><a id="link916" href="FamilyDisplayForward?familyId=916">Circadian clock proteins</a></li><li class="liOpen" ID="node930"><a id="link930" href="FamilyDisplayForward?familyId=930">Claudins</a></li><li class="liOpen" ID="node1069"><a id="link1069" href="FamilyDisplayForward?familyId=1069">Complement system regulators</a></li><li class="liOpen" ID="node1028"><a id="link1028" href="FamilyDisplayForward?familyId=1028">Cytolytic pore-forming proteins</a></li><li class="liOpen" ID="node901">DNA and RNA reader proteins <a href="FamilyDisplayForward?familyId=901&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node1067"><a id="link1067" href="FamilyDisplayForward?familyId=1067">Acylated lysine reader proteins</a></li><li ID="node902"><a id="link902" href="FamilyDisplayForward?familyId=902">Methyllysine reader proteins</a><span class="cgtp"> C</span></li><li ID="node1101"><a id="link1101" href="FamilyDisplayForward?familyId=1101">N6-methyladenosine readers</a></li></ul></li><li class="liOpen" ID="node915"><a id="link915" href="FamilyDisplayForward?familyId=915">EF-hand domain containing proteins</a></li><li class="liOpen" ID="node783"><a id="link783" href="FamilyDisplayForward?familyId=783">Fatty acid-binding proteins</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node1097"><a id="link1097" href="FamilyDisplayForward?familyId=1097">Gasdermins (GSDM)</a></li><li class="liOpen" ID="node1024">Guanine nucleotide exchange factors (GEFs)<ul style="margin-bottom:0px;"><li ID="node1025"><a id="link1025" href="FamilyDisplayForward?familyId=1025">Rho GEFs</a></li></ul></li><li class="liOpen" ID="node784"><a id="link784" href="FamilyDisplayForward?familyId=784">Heat shock proteins</a></li><li class="liOpen" ID="node1098"><a id="link1098" href="FamilyDisplayForward?familyId=1098">High Mobility Group (HMG) proteins</a></li><li class="liOpen" ID="node1066"><a id="link1066" href="FamilyDisplayForward?familyId=1066">Human endogenous retrovirus (HERV) proteins</a></li><li class="liOpen" ID="node1043"><a id="link1043" href="FamilyDisplayForward?familyId=1043">Hypoxia-inducible factors</a></li><li class="liOpen" ID="node954">Immune checkpoint proteins <a href="FamilyDisplayForward?familyId=954&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node953"><a id="link953" href="FamilyDisplayForward?familyId=953">Immune checkpoint catalytic receptors</a></li><li ID="node949"><a id="link949" href="FamilyDisplayForward?familyId=949">Other immune checkpoint proteins</a></li></ul></li><li class="liOpen" ID="node985"><a id="link985" href="FamilyDisplayForward?familyId=985">Immunoglobulin C1-set domain-containing proteins</a></li><li class="liOpen" ID="node987"><a id="link987" href="FamilyDisplayForward?familyId=987">Immunoglobulin C2-set domain-containing proteins</a></li><li class="liOpen" ID="node984"><a id="link984" href="FamilyDisplayForward?familyId=984">Immunoglobulin like domain containing proteins</a></li><li class="liOpen" ID="node868"><a id="link868" href="FamilyDisplayForward?familyId=868">Immunoglobulins</a></li><li class="liOpen" ID="node889"><a id="link889" href="FamilyDisplayForward?familyId=889">Inhibitors of apoptosis (IAP) protein family</a></li><li class="liOpen" ID="node876"><a id="link876" href="FamilyDisplayForward?familyId=876">Kelch-like proteins</a></li><li class="liOpen" ID="node888"><a id="link888" href="FamilyDisplayForward?familyId=888">Kinesins</a></li><li class="liOpen" ID="node934"><a id="link934" href="FamilyDisplayForward?familyId=934">Leucine-rich repeat proteins</a></li><li class="liOpen" ID="node1088"><a id="link1088" href="FamilyDisplayForward?familyId=1088">Lipid transfer/lipopolysaccharide binding proteins</a></li><li class="liOpen" ID="node924"><a id="link924" href="FamilyDisplayForward?familyId=924">Lymphocyte antigens</a></li><li class="liOpen" ID="node919"><a id="link919" href="FamilyDisplayForward?familyId=919">Mitochondrial-associated proteins</a></li><li class="liOpen" ID="node921"><a id="link921" href="FamilyDisplayForward?familyId=921">Myosin binding proteins</a></li><li class="liOpen" ID="node991"><a id="link991" href="FamilyDisplayForward?familyId=991">Neuropilins and Plexins</a></li><li class="liOpen" ID="node941">Non-catalytic pattern recognition receptors <a href="FamilyDisplayForward?familyId=941&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node942"><a id="link942" href="FamilyDisplayForward?familyId=942">Absent in melanoma (AIM)-like receptors (ALRs)</a></li><li ID="node945"><a id="link945" href="FamilyDisplayForward?familyId=945">C-type lectin-like receptors (CLRs)</a></li><li ID="node929"><a id="link929" href="FamilyDisplayForward?familyId=929">Other pattern recognition receptors</a></li></ul></li><li class="liOpen" ID="node914"><a id="link914" href="FamilyDisplayForward?familyId=914">Notch receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node1001"><a id="link1001" href="FamilyDisplayForward?familyId=1001">Nuclear export proteins</a></li><li class="liOpen" ID="node906">Pentraxins <a href="FamilyDisplayForward?familyId=906&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node907"><a id="link907" href="FamilyDisplayForward?familyId=907">Serum pentraxins</a></li></ul></li><li class="liOpen" ID="node891">Regulators of G protein Signaling (RGS) proteins<span class="cgtp"> C</span> <a href="FamilyDisplayForward?familyId=891&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node892"><a id="link892" href="FamilyDisplayForward?familyId=892">RZ family</a><span class="cgtp"> C</span></li><li ID="node893"><a id="link893" href="FamilyDisplayForward?familyId=893">R4 family</a><span class="cgtp"> C</span></li><li ID="node894"><a id="link894" href="FamilyDisplayForward?familyId=894">R7 family</a><span class="cgtp"> C</span></li><li ID="node895"><a id="link895" href="FamilyDisplayForward?familyId=895">R12 family</a><span class="cgtp"> C</span></li></ul></li><li class="liOpen" ID="node932"><a id="link932" href="FamilyDisplayForward?familyId=932">Repulsive guidance molecules</a></li><li class="liOpen" ID="node905"><a id="link905" href="FamilyDisplayForward?familyId=905">Reticulons and associated proteins</a></li><li class="liOpen" ID="node875"><a id="link875" href="FamilyDisplayForward?familyId=875">Ribosomal factors</a></li><li class="liOpen" ID="node1087"><a id="link1087" href="FamilyDisplayForward?familyId=1087">Scavenger receptors</a></li><li class="liOpen" ID="node1093">Sialic acid binding Ig like lectins (SIGLECS) <a href="FamilyDisplayForward?familyId=1093&familyType=OTHER"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node1000"><a id="link1000" href="FamilyDisplayForward?familyId=1000">CD33-related SIGLECs</a></li><li ID="node1094"><a id="link1094" href="FamilyDisplayForward?familyId=1094">SIGLECs (conserved)</a></li></ul></li><li class="liOpen" ID="node785"><a id="link785" href="FamilyDisplayForward?familyId=785">Sigma receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node989"><a id="link989" href="FamilyDisplayForward?familyId=989">Signal regulatory proteins</a></li><li class="liOpen" ID="node1100"><a id="link1100" href="FamilyDisplayForward?familyId=1100">Synuclein proteins</a></li><li class="liOpen" ID="node1047"><a id="link1047" href="FamilyDisplayForward?familyId=1047">Tetraspanins</a></li><li class="liOpen" ID="node972">Transcription factors<ul style="margin-bottom:0px;"><li ID="node1019"><a id="link1019" href="FamilyDisplayForward?familyId=1019">Basic leucine zipper domain TFs</a></li><li ID="node973"><a id="link973" href="FamilyDisplayForward?familyId=973">BTB (POZ) domain containing TFs</a></li><li ID="node974"><a id="link974" href="FamilyDisplayForward?familyId=974">Forkhead box TFs</a></li><li ID="node1099"><a id="link1099" href="FamilyDisplayForward?familyId=1099">NF-kappa B TF proteins</a></li><li ID="node990"><a id="link990" href="FamilyDisplayForward?familyId=990">STAT transcription factors</a></li><li ID="node1085"><a id="link1085" href="FamilyDisplayForward?familyId=1085">TEAD (transcriptional enhanced associate domain) transcription factors</a></li><li ID="node1102"><a id="link1102" href="FamilyDisplayForward?familyId=1102">Zinc finger TFs</a></li></ul></li><li class="liOpen" ID="node995">Transcription factor regulators<ul style="margin-bottom:0px;"><li ID="node996"><a id="link996" href="FamilyDisplayForward?familyId=996">Inhibitors of NF-kappaB (IκB) family proteins</a></li></ul></li><li class="liOpen" ID="node911"><a id="link911" href="FamilyDisplayForward?familyId=911">Transthyretin</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node858"><a id="link858" href="FamilyDisplayForward?familyId=858">Tubulins</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node904"><a id="link904" href="FamilyDisplayForward?familyId=904">Tumour-associated antigens</a></li><li class="liOpen" ID="node903"><a id="link903" href="FamilyDisplayForward?familyId=903">WD repeat-containing proteins</a></li><li class="liOpen" ID="node1058"><a id="link1058" href="FamilyDisplayForward?familyId=1058">Plasmodium multidrug resistance family</a></li></ul></li></ul> </div> </div> </div> <!-- ==================== GRID 16 END ========================================--> </div> <!-- ==================== CONTENT END ============================================ --> <!-- ====== Script to make help pop-up work ====== --> <script> // Popup Window var scrollTop = ''; var newHeight = '100'; /* $(window).bind('scroll', function() { 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