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id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Case fatality rate</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 29 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-29" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">29 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%85%D8%B9%D8%AF%D9%84_%D8%A5%D9%85%D8%A7%D8%AA%D8%A9_%D8%A7%D9%84%D8%AD%D8%A7%D9%84%D8%A7%D8%AA" title="معدل إماتة الحالات – Arabic" lang="ar" hreflang="ar" data-title="معدل إماتة الحالات" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%86%E0%A6%95%E0%A7%8D%E0%A6%B0%E0%A6%BE%E0%A6%A8%E0%A7%8D%E0%A6%A4%E0%A7%87%E0%A6%B0_%E0%A6%AE%E0%A7%83%E0%A6%A4%E0%A7%8D%E0%A6%AF%E0%A7%81%E0%A6%B9%E0%A6%BE%E0%A6%B0" title="আক্রান্তের মৃত্যুহার – Bangla" lang="bn" hreflang="bn" data-title="আক্রান্তের মৃত্যুহার" data-language-autonym="বাংলা" data-language-local-name="Bangla" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Taxa_de_letalitat" title="Taxa de letalitat – Catalan" lang="ca" hreflang="ca" data-title="Taxa de letalitat" data-language-autonym="Català" data-language-local-name="Catalan" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Hrub%C3%A1_m%C3%ADra_smrtelnosti" title="Hrubá míra smrtelnosti – Czech" lang="cs" hreflang="cs" data-title="Hrubá míra smrtelnosti" data-language-autonym="Čeština" data-language-local-name="Czech" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-dag mw-list-item"><a href="https://dag.wikipedia.org/wiki/Case_fatality_rate" title="Case fatality rate – Dagbani" lang="dag" hreflang="dag" data-title="Case fatality rate" data-language-autonym="Dagbanli" data-language-local-name="Dagbani" class="interlanguage-link-target"><span>Dagbanli</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Case_fatality_rate" title="Case fatality rate – Danish" lang="da" hreflang="da" data-title="Case fatality rate" data-language-autonym="Dansk" data-language-local-name="Danish" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Fall-Verstorbenen-Anteil" title="Fall-Verstorbenen-Anteil – German" lang="de" hreflang="de" data-title="Fall-Verstorbenen-Anteil" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Surmavusm%C3%A4%C3%A4r" title="Surmavusmäär – Estonian" lang="et" hreflang="et" data-title="Surmavusmäär" data-language-autonym="Eesti" data-language-local-name="Estonian" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%98%CE%BD%CE%B7%CF%84%CF%8C%CF%84%CE%B7%CF%84%CE%B1" title="Θνητότητα – Greek" lang="el" hreflang="el" data-title="Θνητότητα" data-language-autonym="Ελληνικά" data-language-local-name="Greek" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Tasa_de_letalidad" title="Tasa de letalidad – Spanish" lang="es" hreflang="es" data-title="Tasa de letalidad" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%85%DB%8C%D8%B2%D8%A7%D9%86_%DA%A9%D8%B4%D9%86%D8%AF%DA%AF%DB%8C_%D9%85%D9%88%D8%B1%D8%AF%DB%8C" title="میزان کشندگی موردی – Persian" lang="fa" hreflang="fa" data-title="میزان کشندگی موردی" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Taux_de_l%C3%A9talit%C3%A9" title="Taux de létalité – French" lang="fr" hreflang="fr" data-title="Taux de létalité" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%B9%98%EB%AA%85%EB%A5%A0" title="치명률 – Korean" lang="ko" hreflang="ko" data-title="치명률" data-language-autonym="한국어" data-language-local-name="Korean" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Tingkat_kematian_kasus" title="Tingkat kematian kasus – Indonesian" lang="id" hreflang="id" data-title="Tingkat kematian kasus" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Tasso_di_letalit%C3%A0" title="Tasso di letalità – Italian" lang="it" hreflang="it" data-title="Tasso di letalità" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%A9%D7%99%D7%A2%D7%95%D7%A8_%D7%A7%D7%98%D7%9C%D7%A0%D7%99%D7%95%D7%AA" title="שיעור קטלניות – Hebrew" lang="he" hreflang="he" data-title="שיעור קטלניות" data-language-autonym="עברית" data-language-local-name="Hebrew" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Mir%C5%A1tamumas" title="Mirštamumas – Lithuanian" lang="lt" hreflang="lt" data-title="Mirštamumas" data-language-autonym="Lietuvių" data-language-local-name="Lithuanian" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Kadar_kematian_kes" title="Kadar kematian kes – Malay" lang="ms" hreflang="ms" data-title="Kadar kematian kes" data-language-autonym="Bahasa Melayu" data-language-local-name="Malay" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E8%87%B4%E5%91%BD%E7%8E%87" title="致命率 – Japanese" lang="ja" hreflang="ja" data-title="致命率" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Letallik" title="Letallik – Uzbek" lang="uz" hreflang="uz" data-title="Letallik" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="Uzbek" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Taxa_de_letalidade" title="Taxa de letalidade – Portuguese" lang="pt" hreflang="pt" data-title="Taxa de letalidade" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9B%D0%B5%D1%82%D0%B0%D0%BB%D1%8C%D0%BD%D0%BE%D1%81%D1%82%D1%8C" title="Летальность – Russian" lang="ru" hreflang="ru" data-title="Летальность" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-si mw-list-item"><a href="https://si.wikipedia.org/wiki/%E0%B7%83%E0%B7%92%E0%B6%AF%E0%B7%8A%E0%B6%B0%E0%B7%92_%E0%B6%B8%E0%B6%BB%E0%B6%AB_%E0%B6%85%E0%B6%B1%E0%B7%94%E0%B6%B4%E0%B7%8F%E0%B6%AD%E0%B6%BA" title="සිද්ධි මරණ අනුපාතය – Sinhala" lang="si" hreflang="si" data-title="සිද්ධි මරණ අනුපාතය" data-language-autonym="සිංහල" data-language-local-name="Sinhala" class="interlanguage-link-target"><span>සිංහල</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Tapauskuolleisuus" title="Tapauskuolleisuus – Finnish" lang="fi" hreflang="fi" data-title="Tapauskuolleisuus" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Vaka_%C3%B6l%C3%BCm_oran%C4%B1" title="Vaka ölüm oranı – Turkish" lang="tr" hreflang="tr" data-title="Vaka ölüm oranı" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9B%D0%B5%D1%82%D0%B0%D0%BB%D1%8C%D0%BD%D1%96%D1%81%D1%82%D1%8C" title="Летальність – Ukrainian" lang="uk" hreflang="uk" data-title="Летальність" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/T%E1%BB%B7_l%E1%BB%87_t%E1%BB%AD_vong_ca_b%E1%BB%87nh" title="Tỷ lệ tử vong ca bệnh – Vietnamese" lang="vi" hreflang="vi" data-title="Tỷ lệ tử vong ca bệnh" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-wa mw-list-item"><a href="https://wa.wikipedia.org/wiki/Morance_pa_mal%C3%A5de" title="Morance pa malåde – Walloon" lang="wa" hreflang="wa" data-title="Morance pa malåde" data-language-autonym="Walon" data-language-local-name="Walloon" class="interlanguage-link-target"><span>Walon</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E8%87%B4%E6%AD%BB%E7%8E%87" title="致死率 – Chinese" lang="zh" hreflang="zh" data-title="致死率" 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dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Medical measurement formula</div> <style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">Not to be confused with <a href="/wiki/Mortality_rate" title="Mortality rate">mortality rate</a>.</div> <p>In <a href="/wiki/Epidemiology" title="Epidemiology">epidemiology</a>, <b>case fatality rate</b> (<b>CFR</b>) – or sometimes more accurately <b>case-fatality risk</b> – is the proportion of people who have been <a href="/wiki/Medical_diagnosis" title="Medical diagnosis">diagnosed</a> with a certain disease and end up <a href="/wiki/Cause_of_death" title="Cause of death">dying of it</a>. Unlike a disease's <a href="/wiki/Mortality_rate" title="Mortality rate">mortality rate</a>, the CFR does not take into account the time period between disease onset and death. A CFR is generally expressed as a percentage. It is a measure of disease <a href="/wiki/Lethality" title="Lethality">lethality</a>, and thus may change with different <a href="/wiki/Therapy" title="Therapy">treatments</a>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> CFRs are most often used for with discrete, limited-time courses, such as acute <a href="/wiki/Infection" title="Infection">infections</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Terminology">Terminology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Case_fatality_rate&action=edit&section=1" title="Edit section: Terminology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The <i><a href="/wiki/Mortality_rate" title="Mortality rate">mortality rate</a></i> – often confused with the CFR – is a measure of the relative number of deaths (either in general, or due to a specific cause) within the entire population per unit of time.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> A CFR, in contrast, is the number of deaths among the number of diagnosed cases only, regardless of time or total population.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p><p>From a mathematical point of view, by taking values between 0 and 1 or 0% and 100%, CFRs are actually a measure of <a href="/wiki/Risk" title="Risk">risk</a> (<b>case fatality risk</b>) – that is, they are a <a href="/wiki/Incidence_proportions" class="mw-redirect" title="Incidence proportions">proportion of incidence</a>, although they do not reflect a <a href="/wiki/Incidence_(epidemiology)" title="Incidence (epidemiology)">disease's incidence</a>. They are neither <a href="/wiki/Rate_(mathematics)" title="Rate (mathematics)">rates</a>, <a href="/wiki/Incidence_rate" class="mw-redirect" title="Incidence rate">incidence rates</a>, nor <a href="/wiki/Ratio" title="Ratio">ratios</a> (none of which are limited to the range 0–1). They do not take into account time from disease onset to death.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>Sometimes the term <b>case fatality ratio</b> is used interchangeably with <i>case fatality rate</i>, but they are not the same. A case fatality ratio is a comparison between two different case fatality rates, expressed as a ratio. It is used to compare the severity of different diseases or to assess the impact of interventions.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>Because the CFR is not an <a href="/wiki/Incidence_rate" class="mw-redirect" title="Incidence rate">incidence rate</a> by not measuring frequency, some authors note that a more appropriate term is <b>case fatality proportion</b>.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> We are to be believers of the third world rights and our own family beliefs, we section our controlling manners into places of interest and take some pleasure away from the beliefs we have. Strangely we care in care of our lives and sometimes attempt to be excessive in our religious news and matters, we conclude some of our professional costumers to take new trends in costumes and allow them to blame another for their over zested beliefs. We dress up to stand up like the Karttunen family may have deletion of MINNA a slogan of hate. </p> <div class="mw-heading mw-heading2"><h2 id="Example_calculation">Example calculation</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Case_fatality_rate&action=edit&section=2" title="Edit section: Example calculation"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>If 100 people in a community are diagnosed with the same disease, and 9 of them subsequently die from the effects of the disease, the CFR would be 9%. If some of the cases have not yet resolved (neither died nor fully recovered) at the time of analysis, a later analysis might take into account additional deaths and arrive at a higher estimate of the CFR, if the unresolved cases were included as recovered in the earlier analysis. Alternatively, it might later be established that a higher number of people were subclinically infected with the pathogen, resulting in an IFR below the CFR.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (May 2023)">citation needed</span></a></i>]</sup> </p><p>A CFR may only be calculated from cases that have been resolved through either death or recovery. The preliminary CFR, for example, of a newly occurring disease with a high daily increase and long resolution time would be substantially lower than the final CFR, if unresolved cases were not excluded from the calculation, but added to the denominator only. </p><p><span class="mwe-math-element"><span class="mwe-math-mathml-inline mwe-math-mathml-a11y" style="display: none;"><math xmlns="http://www.w3.org/1998/Math/MathML" alttext="{\displaystyle {\text{CFR in }}{\%}={\frac {\text{Number of deaths from disease}}{\text{Number of confirmed cases of disease}}}\times 100}"> <semantics> <mrow class="MJX-TeXAtom-ORD"> <mstyle displaystyle="true" scriptlevel="0"> <mrow class="MJX-TeXAtom-ORD"> <mtext>CFR in </mtext> </mrow> <mrow class="MJX-TeXAtom-ORD"> <mi mathvariant="normal">%</mi> </mrow> <mo>=</mo> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mtext>Number of deaths from disease</mtext> <mtext>Number of confirmed cases of disease</mtext> </mfrac> </mrow> <mo>×</mo> <mn>100</mn> </mstyle> </mrow> <annotation encoding="application/x-tex">{\displaystyle {\text{CFR in }}{\%}={\frac {\text{Number of deaths from disease}}{\text{Number of confirmed cases of disease}}}\times 100}</annotation> </semantics> </math></span><img src="https://wikimedia.org/api/rest_v1/media/math/render/svg/10f40c61f1597a303210cd0f115d81b2570eabd8" class="mwe-math-fallback-image-inline mw-invert skin-invert" aria-hidden="true" style="vertical-align: -2.005ex; width:57.143ex; height:5.509ex;" alt="{\displaystyle {\text{CFR in }}{\%}={\frac {\text{Number of deaths from disease}}{\text{Number of confirmed cases of disease}}}\times 100}"></span><sup id="cite_ref-:0_8-0" class="reference"><a href="#cite_note-:0-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Infection_fatality_rate">Infection fatality rate</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Case_fatality_rate&action=edit&section=3" title="Edit section: Infection fatality rate"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Like the case fatality rate, the term <b>infection fatality rate</b> (IFR) also applies to <a href="/wiki/Infectious_disease" class="mw-redirect" title="Infectious disease">infectious diseases</a>, but represents the proportion of deaths among all infected individuals, including all <a href="/wiki/Asymptomatic" title="Asymptomatic">asymptomatic</a> and undiagnosed subjects. It is closely related to the CFR, but attempts to additionally account for inapparent infections among healthy people.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> The IFR differs from the CFR in that it aims to estimate the fatality rate in both sick and healthy infected: the detected disease (cases) and those with an undetected disease (asymptomatic and not tested group).<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Individuals who are infected, but show no symptoms, are said to have <a href="/wiki/Subclinical_infection" title="Subclinical infection"><i>inapparent</i>, <i>silent</i> or <i>subclinical</i></a> infections and may inadvertently infect others. By definition, the IFR cannot exceed the CFR, because the former adds asymptomatic cases to its denominator. </p><p><span class="mwe-math-element"><span class="mwe-math-mathml-inline mwe-math-mathml-a11y" style="display: none;"><math xmlns="http://www.w3.org/1998/Math/MathML" alttext="{\displaystyle {\text{IFR in }}{\%}={\frac {\text{Number of deaths from disease}}{\text{Number of infected individuals}}}\times 100}"> <semantics> <mrow class="MJX-TeXAtom-ORD"> <mstyle displaystyle="true" scriptlevel="0"> <mrow class="MJX-TeXAtom-ORD"> <mtext>IFR in </mtext> </mrow> <mrow class="MJX-TeXAtom-ORD"> <mi mathvariant="normal">%</mi> </mrow> <mo>=</mo> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mtext>Number of deaths from disease</mtext> <mtext>Number of infected individuals</mtext> </mfrac> </mrow> <mo>×</mo> <mn>100</mn> </mstyle> </mrow> <annotation encoding="application/x-tex">{\displaystyle {\text{IFR in }}{\%}={\frac {\text{Number of deaths from disease}}{\text{Number of infected individuals}}}\times 100}</annotation> </semantics> </math></span><img src="https://wikimedia.org/api/rest_v1/media/math/render/svg/7bd0e8da8d34da3fdf8b3a71cefe6f617b6d0104" class="mwe-math-fallback-image-inline mw-invert skin-invert" aria-hidden="true" style="vertical-align: -2.005ex; width:50.2ex; height:5.509ex;" alt="{\displaystyle {\text{IFR in }}{\%}={\frac {\text{Number of deaths from disease}}{\text{Number of infected individuals}}}\times 100}"></span><sup id="cite_ref-:0_8-1" class="reference"><a href="#cite_note-:0-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Examples">Examples</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Case_fatality_rate&action=edit&section=4" title="Edit section: Examples"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/List_of_human_disease_case_fatality_rates" title="List of human disease case fatality rates">List of human disease case fatality rates</a></div> <p>Some examples will suggest the range of possible CFRs for diseases in the real world: </p> <ul><li>The CFR for the <a href="/wiki/1918_flu_pandemic" class="mw-redirect" title="1918 flu pandemic">Spanish (1918) flu</a> was greater than 2.5%, while the <a href="/wiki/Asian_flu" class="mw-redirect" title="Asian flu">Asian (1957-58)</a> and <a href="/wiki/Hong_Kong_flu" title="Hong Kong flu">Hong Kong (1968-69) flus</a> both had a CFR of about 0.2%.<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-taubenberger2006_12-0" class="reference"><a href="#cite_note-taubenberger2006-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-li2008_13-0" class="reference"><a href="#cite_note-li2008-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup></li> <li>As of 17 Feb 2025, <a href="/wiki/Coronavirus_disease_2019" class="mw-redirect" title="Coronavirus disease 2019">coronavirus disease 2019</a> has an overall CFR of 0.91%, although the CFRs of earlier strains of COVID-19 was around 2%, the CFRs for original <a href="/wiki/SARS" title="SARS">SARS</a> and <a href="/wiki/MERS" title="MERS">MERS</a> are about 11% and 34%, respectively.<sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup></li> <li>The CFR for <a href="/wiki/Yellow_fever" title="Yellow fever">yellow fever</a> is about 5-6% (but 40-50% in severe cases).<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup></li> <li><a href="/wiki/Legionnaires%27_disease" title="Legionnaires' disease">Legionnaires' disease</a> has a CFR of about 15%.<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup><sup class="reference nowrap"><span title="Page / location: 665">: 665 </span></sup></li> <li>Left untreated, <a href="/wiki/Bubonic_plague" title="Bubonic plague">bubonic plague</a> will have a CFR of up to 60%.<sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup><sup class="reference nowrap"><span title="Page / location: 57">: 57 </span></sup> With antibiotic treatment, the CFR for bubonic plague is 17%, <a href="/wiki/Pneumonic_plague" title="Pneumonic plague">pneumonic</a> 29% and <a href="/wiki/Septicaemic_plague" class="mw-redirect" title="Septicaemic plague">septicaemic</a> 45%.<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup></li> <li>Active <a href="/wiki/Tuberculosis" title="Tuberculosis">tuberculosis</a>, the infection with the highest mortality rate, has a CFR of 43% in the absence of <a href="/wiki/HIV" title="HIV">HIV</a>.<sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-25" class="reference"><a href="#cite_note-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup></li> <li><a href="/wiki/Ebola_virus_disease" class="mw-redirect" title="Ebola virus disease">Ebola virus disease</a>, one of the infections with the highest lethality, has a CFR as high as 90%.<sup id="cite_ref-emedicine.com_26-0" class="reference"><a href="#cite_note-emedicine.com-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup></li> <li><a href="/wiki/Naegleriasis" title="Naegleriasis">Naegleriasis</a> (also known as primary amoebic meningoencephalitis), has a CFR greater than 95%, with a few of the survivors having been treated with <a href="/wiki/Heroic_measure" title="Heroic measure">heroic doses</a> of amphotericin B and other <a href="/wiki/Off-label_use" title="Off-label use">off-label drugs</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (April 2023)">citation needed</span></a></i>]</sup></li> <li><a href="/wiki/Rabies" title="Rabies">Rabies</a> has a CFR greater than 99% in unvaccinated individuals.<sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> A few people have survived either by being vaccinated (but <a href="/wiki/Post-exposure_prophylaxis" title="Post-exposure prophylaxis">after symptoms started, or else later than ideal</a>), or more recently, by being put into a medically induced coma.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (April 2023)">citation needed</span></a></i>]</sup></li></ul> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Case_fatality_rate&action=edit&section=5" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1266661725">.mw-parser-output .portalbox{padding:0;margin:0.5em 0;display:table;box-sizing:border-box;max-width:175px;list-style:none}.mw-parser-output .portalborder{border:1px solid var(--border-color-base,#a2a9b1);padding:0.1em;background:var(--background-color-neutral-subtle,#f8f9fa)}.mw-parser-output .portalbox-entry{display:table-row;font-size:85%;line-height:110%;height:1.9em;font-style:italic;font-weight:bold}.mw-parser-output .portalbox-image{display:table-cell;padding:0.2em;vertical-align:middle;text-align:center}.mw-parser-output .portalbox-link{display:table-cell;padding:0.2em 0.2em 0.2em 0.3em;vertical-align:middle}@media(min-width:720px){.mw-parser-output .portalleft{margin:0.5em 1em 0.5em 0}.mw-parser-output .portalright{clear:right;float:right;margin:0.5em 0 0.5em 1em}}</style><ul role="navigation" aria-label="Portals" class="noprint portalbox portalborder portalright"> <li class="portalbox-entry"><span class="portalbox-image"><span class="noviewer" typeof="mw:File"><span><img alt="icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/12px-WHO_Rod.svg.png" decoding="async" width="12" height="28" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/18px-WHO_Rod.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/24px-WHO_Rod.svg.png 2x" data-file-width="107" data-file-height="250" /></span></span></span><span class="portalbox-link"><a href="/wiki/Portal:Medicine" title="Portal:Medicine">Medicine portal</a></span></li></ul> <ul><li><a href="/wiki/List_of_human_disease_case_fatality_rates" title="List of human disease case fatality rates">List of human disease case fatality rates</a></li> <li><a href="/wiki/Mortality_rate" title="Mortality rate">Mortality rate</a> – Deaths per 1000 individuals per year</li> <li><a href="/wiki/Pandemic_severity_index" title="Pandemic severity index">Pandemic severity index</a> – Proposed measure of the severity of influenza</li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Case_fatality_rate&action=edit&section=6" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text">Rebecca A. Harrington, <a rel="nofollow" class="external text" href="https://www.britannica.com/EBchecked/topic/2059316">Case fatality rate</a> at the <i><a href="/wiki/Encyclop%C3%A6dia_Britannica" title="Encyclopædia Britannica">Encyclopædia Britannica</a></i></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text">For example, a <a href="/wiki/Diabetes" title="Diabetes">diabetes</a> mortality rate of 5 per 1,000 or 500 per 100,000 characterizes the observation of 50 deaths due to diabetes in a population of 10,000 in a given year, resulting in a yearly diabetes mortality rate of 0.5%, far below the actual diabetic individual's fatality risk. (See Harrington, <i><a href="/wiki/Op._cit." title="Op. cit.">Op. cit.</a></i>.)</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20200327171140/https://www.elsevier.com/__data/assets/pdf_file/0010/977698/Coronavirus-novel-coronavirus-COVID-19-infection_2020-03-25.pdf">"Coronavirus: novel coronavirus (COVID-19) infection"</a> <span class="cs1-format">(PDF)</span>. <i>Elsevier</i>. 2020-03-25. 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Retrieved <span class="nowrap">2020-03-27</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Elsevier&rft.atitle=Coronavirus%3A+novel+coronavirus+%28COVID-19%29+infection&rft.date=2020-03-25&rft_id=https%3A%2F%2Fwww.elsevier.com%2F__data%2Fassets%2Fpdf_file%2F0010%2F977698%2FCoronavirus-novel-coronavirus-COVID-19-infection_2020-03-25.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACase+fatality+rate" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text">Entry "Case fatality rate" in <a href="/wiki/John_M._Last" title="John M. 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Retrieved <span class="nowrap">2020-03-25</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Field+Epidemiology+Manual+Wiki&rft.atitle=Attack+rates+and+case+fatality&rft.date=2014-05-28&rft.aulast=Bosman&rft.aufirst=Arnold&rft_id=https%3A%2F%2Fwiki.ecdc.europa.eu%2Ffem%2FPages%2FAttack%2520rates%2520and%2520case%2520fatality.aspx&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACase+fatality+rate" class="Z3988"></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text">Peter Cummings: <a rel="nofollow" class="external text" href="https://books.google.com/books?id=y8ySDwAAQBAJ&dq=This+proportion+has+been+called+case+fatality&pg=PT44"><i>Analysis of Incidence Rates.</i></a> In: CRC Press (2019).</span> </li> <li id="cite_note-:0-8"><span class="mw-cite-backlink">^ <a href="#cite_ref-:0_8-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-:0_8-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.who.int/news-room/commentaries/detail/estimating-mortality-from-covid-19">"Estimating mortality from COVID-19"</a>. <i>www.who.int</i><span class="reference-accessdate">. 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class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10790329">10790329</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23245604">23245604</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:1541253">1541253</a>.</cite><span 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class="Z3988"></span></span> </li> <li id="cite_note-25"><span class="mw-cite-backlink"><b><a href="#cite_ref-25">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTiemersmavan_der_WerfBorgdorffWilliams2011" class="citation journal cs1">Tiemersma, Edine W.; van der Werf, Marieke J.; Borgdorff, Martien W.; Williams, Brian G.; Nagelkerke, Nico J. 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WebMd<span class="reference-accessdate">. Retrieved <span class="nowrap">2008-10-06</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=eMedicine&rft.atitle=Ebola+Virus&rft.date=2008-04-02&rft.au=King%2C+John+W&rft_id=http%3A%2F%2Fwww.emedicine.com%2FMED%2Ftopic626.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACase+fatality+rate" class="Z3988"></span></span> </li> <li id="cite_note-27"><span class="mw-cite-backlink"><b><a href="#cite_ref-27">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.who.int/mediacentre/factsheets/fs099/en/">"Rabies Fact Sheet N°99"</a>. <i>World Health Organization</i>. July 2013<span class="reference-accessdate">. Retrieved <span class="nowrap">28 February</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=World+Health+Organization&rft.atitle=Rabies+Fact+Sheet+N%C2%B099&rft.date=2013-07&rft_id=https%3A%2F%2Fwww.who.int%2Fmediacentre%2Ffactsheets%2Ffs099%2Fen%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ACase+fatality+rate" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Case_fatality_rate&action=edit&section=7" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20051228190215/http://www.ktl.fi/publications/monica/carpfish/appendd/cfdef.htm">Definitions of case fatality for coronary events in the WHO MONICA Project</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20090501034534/http://www.agoravox.com/article.php3?id_article=9820">Swine flu: what do CFR, virulence and mortality rate mean?</a></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul 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class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Death" title="Template:Death"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Death" title="Template talk:Death"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Death" title="Special:EditPage/Template:Death"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Death315" style="font-size:114%;margin:0 4em"><a href="/wiki/Death" title="Death">Death</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">In medicine</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Cell_death14" scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cell_death" title="Cell death">Cell death</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Necrosis" title="Necrosis">Necrosis</a> <ul><li><a href="/wiki/Avascular_necrosis" title="Avascular necrosis">Avascular necrosis</a></li> <li><a href="/wiki/Coagulative_necrosis" title="Coagulative necrosis">Coagulative necrosis</a></li> <li><a href="/wiki/Liquefactive_necrosis" title="Liquefactive necrosis">Liquefactive necrosis</a></li> <li><a href="/wiki/Gangrene" title="Gangrene">Gangrenous necrosis</a></li> <li><a href="/wiki/Caseous_necrosis" title="Caseous necrosis">Caseous necrosis</a></li> <li><a href="/wiki/Fat_necrosis" title="Fat necrosis">Fat necrosis</a></li> <li><a href="/wiki/Fibrinoid_necrosis" title="Fibrinoid necrosis">Fibrinoid necrosis</a></li> <li><a href="/wiki/Temporal_lobe_necrosis" title="Temporal lobe necrosis">Temporal lobe necrosis</a></li></ul></li> <li><a href="/wiki/Programmed_cell_death" title="Programmed cell death">Programmed cell death</a> <ul><li><a href="/wiki/Activation-induced_cell_death" title="Activation-induced cell death">AICD</a></li> <li><a href="/wiki/Anoikis" title="Anoikis">Anoikis</a></li> <li><a href="/wiki/Apoptosis" title="Apoptosis">Apoptosis</a></li> <li><a href="/wiki/Autophagy" title="Autophagy">Autophagy</a></li> <li><a href="/wiki/Intrinsic_apoptosis" class="mw-redirect" title="Intrinsic apoptosis">Intrinsic apoptosis</a></li> <li><a href="/wiki/Necroptosis" title="Necroptosis">Necroptosis</a></li> <li><a href="/wiki/Paraptosis" title="Paraptosis">Paraptosis</a></li> <li><a href="/wiki/Parthanatos" title="Parthanatos">Parthanatos</a></li> <li><a href="/wiki/Phenoptosis" title="Phenoptosis">Phenoptosis</a></li> <li><a href="/wiki/Pseudoapoptosis" title="Pseudoapoptosis">Pseudoapoptosis</a></li> <li><a href="/wiki/Pyroptosis" title="Pyroptosis">Pyroptosis</a></li></ul></li> <li><a href="/wiki/Autolysis_(biology)" title="Autolysis (biology)">Autolysis</a></li> <li><a href="/wiki/Autoschizis" title="Autoschizis">Autoschizis</a></li> <li><a href="/wiki/Eschar" title="Eschar">Eschar</a></li> <li><a href="/wiki/Immunogenic_cell_death" title="Immunogenic cell death">Immunogenic cell death</a></li> <li><a href="/wiki/Ischemic_cell_death" title="Ischemic cell death">Ischemic cell death</a></li> <li><a href="/wiki/Pyknosis" title="Pyknosis">Pyknosis</a></li> <li><a href="/wiki/Karyorrhexis" title="Karyorrhexis">Karyorrhexis</a></li> <li><a href="/wiki/Karyolysis" title="Karyolysis">Karyolysis</a></li> <li><a href="/wiki/Mitotic_catastrophe" title="Mitotic catastrophe">Mitotic catastrophe</a></li> <li><a href="/wiki/Suicide_gene" title="Suicide gene">Suicide gene</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion" title="Abortion">Abortion</a></li> <li><a href="/wiki/Accidental_death" title="Accidental death">Accidental death</a></li> <li><a href="/wiki/Autopsy" title="Autopsy">Autopsy</a></li> <li><a href="/wiki/Brain_death" title="Brain death">Brain death</a> <ul><li><a href="/wiki/Brainstem_death" title="Brainstem death">Brainstem death</a></li></ul></li> <li><a href="/wiki/Clinical_death" title="Clinical death">Clinical death</a> <ul><li><a href="/wiki/Dead_on_arrival" title="Dead on arrival">DOA</a></li></ul></li> <li><a href="/wiki/Manner_of_death" title="Manner of death">Death by natural causes</a></li> <li><a href="/wiki/Death_rattle" title="Death rattle">Death rattle</a></li> <li><a href="/wiki/Dysthanasia" title="Dysthanasia">Dysthanasia</a></li> <li><a href="/wiki/End-of-life_care" title="End-of-life care">End-of-life care</a></li> <li><a href="/wiki/Euthanasia" title="Euthanasia">Euthanasia</a></li> <li><a href="/wiki/Lazarus_sign" title="Lazarus sign">Lazarus sign</a></li> <li><a href="/wiki/Lazarus_syndrome" title="Lazarus syndrome">Lazarus syndrome</a></li> <li><a href="/wiki/Legal_death#Medical_declaration" title="Legal death">Medical declaration of death</a></li> <li><a href="/wiki/Organ_donation" title="Organ donation">Organ donation</a></li> <li><a href="/wiki/Terminal_illness" title="Terminal illness">Terminal illness</a></li> <li><a href="/wiki/Manner_of_death" title="Manner of death">Unnatural death</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Category:Death-related_lists" title="Category:Death-related lists">Lists</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/List_of_causes_of_death_by_rate" title="List of causes of death by rate">Causes of death by rate</a></li> <li><a href="/wiki/Lists_of_deaths_by_year" title="Lists of deaths by year">Notable deaths by year</a></li> <li><a href="/wiki/List_of_expressions_related_to_death" class="mw-redirect" title="List of expressions related to death">Expressions related to death</a></li> <li><a href="/wiki/List_of_natural_disasters_by_death_toll" title="List of natural disasters by death toll">Natural disasters</a></li> <li><a href="/wiki/Lists_of_people_by_cause_of_death" title="Lists of people by cause of death">People by cause of death</a></li> <li><a href="/wiki/List_of_premature_obituaries" class="mw-redirect" title="List of premature obituaries">Premature obituaries</a></li> <li><a href="/wiki/Preventable_causes_of_death" title="Preventable causes of death">Preventable causes of death</a></li> <li><a href="/wiki/List_of_unusual_deaths" class="mw-redirect" title="List of unusual deaths">Unusual deaths</a></li> <li><a href="/wiki/List_of_ways_people_dishonor_the_dead" title="List of ways people dishonor the dead">List of ways people dishonor the dead</a></li> <li><a href="/wiki/List_of_ways_people_honor_the_dead" class="mw-redirect" title="List of ways people honor the dead">List of ways people honor the dead</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Mortality</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Birthday_effect" title="Birthday effect">Birthday effect</a></li> <li><a href="/wiki/Child_mortality" title="Child mortality">Child mortality</a></li> <li><a href="/wiki/Excess_mortality" title="Excess mortality">Excess mortality</a></li> <li><a href="/wiki/Gompertz%E2%80%93Makeham_law_of_mortality" title="Gompertz–Makeham law of mortality">Gompertz–Makeham law of mortality</a></li> <li><a href="/wiki/Infant_mortality" title="Infant mortality">Infant mortality</a></li> <li><a href="/wiki/Karoshi" title="Karoshi">Karoshi</a></li> <li><a href="/wiki/Maternal_death" title="Maternal death">Maternal death</a></li> <li><a href="/wiki/Maternal_mortality_in_fiction" title="Maternal mortality in fiction">Maternal mortality in fiction</a></li> <li><i><a href="/wiki/Memento_mori" title="Memento mori">Memento mori</a></i></li> <li><a href="/wiki/Micromort" title="Micromort">Micromort</a></li> <li><a href="/wiki/Mortality_rate" title="Mortality rate">Mortality rate</a> <ul><li><a href="/wiki/Risk_adjusted_mortality_rate" title="Risk adjusted mortality rate">RAMR</a></li></ul></li> <li><a href="/wiki/Mortality_salience" title="Mortality salience">Mortality salience</a></li> <li><a href="/wiki/Perinatal_mortality" title="Perinatal mortality">Perinatal mortality</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">After death</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><b><a href="/wiki/Cadaver" title="Cadaver">Body</a></b></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Stages</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Pallor_mortis" title="Pallor mortis">Pallor mortis</a></li> <li><a href="/wiki/Livor_mortis" title="Livor mortis">Livor mortis</a></li> <li><a href="/wiki/Algor_mortis" title="Algor mortis">Algor mortis</a></li> <li><a href="/wiki/Rigor_mortis" title="Rigor mortis">Rigor mortis</a></li> <li><a href="/wiki/Putrefaction" title="Putrefaction">Putrefaction</a></li> <li><a href="/wiki/Decomposition" title="Decomposition">Decomposition</a></li> <li><a href="/wiki/Skeletonization" title="Skeletonization">Skeletonization</a></li> <li><a href="/wiki/Fossil" title="Fossil">Fossilization</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Preservation</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cryopreservation" title="Cryopreservation">Cryopreservation</a> <ul><li><a href="/wiki/Cryonics" title="Cryonics">Cryonics</a></li> <li><a href="/wiki/Neuropreservation" class="mw-redirect" title="Neuropreservation">Neuropreservation</a></li></ul></li> <li><a href="/wiki/Embalming" title="Embalming">Embalming</a></li> <li><a href="/wiki/Maceration_(bone)" title="Maceration (bone)">Maceration</a></li> <li><a href="/wiki/Mummy" title="Mummy">Mummification</a></li> <li><a href="/wiki/Plastination" title="Plastination">Plastination</a></li> <li><a href="/wiki/Prosection" title="Prosection">Prosection</a></li> <li><a href="/wiki/Taxidermy" title="Taxidermy">Taxidermy</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Disposal_of_human_corpses" title="Disposal of human corpses">Disposal</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Burial" title="Burial">Burial</a> <ul><li><a href="/wiki/Natural_burial" title="Natural burial">Natural burial</a></li> <li><a href="/wiki/Sky_burial" title="Sky burial">Sky burial</a></li></ul></li> <li><a href="/wiki/Cremation" title="Cremation">Cremation</a></li> <li><a href="/wiki/Dismemberment" title="Dismemberment">Dismemberment</a></li> <li><a href="/wiki/Excarnation" title="Excarnation">Excarnation</a></li> <li><a href="/wiki/Promession" title="Promession">Promession</a></li> <li><a href="/wiki/Alkaline_hydrolysis_(body_disposal)" class="mw-redirect" title="Alkaline hydrolysis (body disposal)">Resomation</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Beating_heart_cadaver" title="Beating heart cadaver">Beating heart cadaver</a></li> <li><a href="/wiki/Body_donation" title="Body donation">Body donation</a></li> <li><a href="/wiki/Cadaveric_spasm" title="Cadaveric spasm">Cadaveric spasm</a></li> <li><a href="/wiki/Coffin_birth" title="Coffin birth">Coffin birth</a></li> <li><a href="/wiki/Death_erection" title="Death erection">Death erection</a></li> <li><a href="/wiki/Dissection" title="Dissection">Dissection</a></li> <li><a href="/wiki/Gibbeting" title="Gibbeting">Gibbeting</a></li> <li><a href="/wiki/Postmortem_caloricity" title="Postmortem caloricity">Postmortem caloricity</a></li> <li><a href="/wiki/Post-mortem_interval" title="Post-mortem interval">Post-mortem interval</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;font-weight:normal;"><b>Other aspects</b></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Carrion" title="Carrion">Carrion</a></li> <li><a href="/wiki/Cemetery" title="Cemetery">Cemetery</a></li> <li><a href="/wiki/Consciousness_after_death" class="mw-redirect" title="Consciousness after death">Consciousness after death</a> <ul><li><a href="/wiki/Afterlife" title="Afterlife">Afterlife</a></li> <li><a href="/wiki/Tukdam" title="Tukdam">Tukdam</a></li></ul></li> <li><a href="/wiki/Category:Death_customs" title="Category:Death customs">Customs</a></li> <li><a href="/wiki/Crematorium" title="Crematorium">Crematorium</a></li> <li><a href="/wiki/Desecration_of_graves" class="mw-redirect" title="Desecration of graves">Desecration of graves</a></li> <li><a href="/wiki/Eternal_oblivion" title="Eternal oblivion">Eternal oblivion</a></li> <li><a href="/wiki/Medical_examiner" title="Medical examiner">Examination</a></li> <li><a href="/wiki/Funeral" title="Funeral">Funeral</a></li> <li><a href="/wiki/Grief" title="Grief">Grief</a></li> <li><a href="/wiki/Death_and_the_Internet" title="Death and the Internet">Internet</a></li> <li><a href="/wiki/Death_midwife" title="Death midwife">Midwife</a></li> <li><a href="/wiki/Mourning" title="Mourning">Mourning</a> <ul><li><a href="/wiki/Online_mourning" title="Online mourning">Online mourning</a></li></ul></li> <li><a href="/wiki/Obituary" title="Obituary">Obituary</a></li> <li><a href="/wiki/Reincarnation" title="Reincarnation">Reincarnation</a> <ul><li><a href="/wiki/Palingenesis" title="Palingenesis">Palingenesis</a></li> <li><a href="/wiki/Sa%E1%B9%83s%C4%81ra" title="Saṃsāra">Saṃsāra</a></li></ul></li> <li><a href="/wiki/Resurrection" title="Resurrection">Resurrection</a></li> <li><a href="/wiki/Underworld" title="Underworld">Underworld</a></li> <li><a href="/wiki/Vigil" title="Vigil">Vigil</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Paranormal</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ghost" title="Ghost">Ghosts</a></li> <li><a href="/wiki/Near-death_experience" title="Near-death experience">Near-death experience</a></li> <li><a href="/wiki/Near-death_studies" title="Near-death studies">Near-death studies</a></li> <li><a href="/wiki/Necromancy" title="Necromancy">Necromancy</a></li> <li><a href="/wiki/Out-of-body_experience" title="Out-of-body experience">Out-of-body experience</a></li> <li><a href="/wiki/Template:Reincarnation_research" title="Template:Reincarnation research">Reincarnation research</a></li> <li><a href="/wiki/S%C3%A9ance" title="Séance">Séance</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Legal</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion_law" title="Abortion law">Abortion law</a></li> <li><a href="/wiki/Administration_(probate_law)" title="Administration (probate law)">Administration</a></li> <li><a href="/wiki/Capital_punishment" title="Capital punishment">Capital punishment</a></li> <li><a href="/wiki/Cause_of_death" title="Cause of death">Cause of death</a></li> <li><a href="/wiki/Civil_death" title="Civil death">Civil death</a></li> <li><a href="/wiki/Coroner" title="Coroner">Coroner</a></li> <li><a href="/wiki/Death-qualified_jury" title="Death-qualified jury">Death-qualified jury</a></li> <li><a href="/wiki/Death_certificate" title="Death certificate">Death certificate</a></li> <li><a href="/wiki/Presumption_of_death" title="Presumption of death">Declared death <i>in absentia</i></a></li> <li><a href="/wiki/Death_row" title="Death row">Death row</a></li> <li><a href="/wiki/Dying_declaration" title="Dying declaration">Dying declaration</a></li> <li><a href="/wiki/Inquest" title="Inquest">Inquest</a></li> <li><a href="/wiki/Legal_death" title="Legal death">Legal death</a></li> <li><a href="/wiki/Murder" title="Murder">Murder</a></li> <li><a href="/wiki/Necropolitics" title="Necropolitics">Necropolitics</a></li> <li><a href="/wiki/Prohibition_of_dying" title="Prohibition of dying">Prohibition of dying</a></li> <li><a href="/wiki/Right_to_die" title="Right to die">Right to die</a></li> <li><a href="/wiki/Suspicious_death" title="Suspicious death">Suspicious death</a></li> <li><a href="/wiki/Trust_(law)" title="Trust (law)">Trust law</a></li> <li><a href="/wiki/Will_and_testament" title="Will and testament">Will</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Fields</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=Death_tech&action=edit&redlink=1" class="new" title="Death tech (page does not exist)">Death tech</a><span class="noprint" style="font-size:85%; font-style: normal;"> [<a href="https://pt.wikipedia.org/wiki/Death_Tech" class="extiw" title="pt:Death Tech">pt</a>]</span></li> <li><a href="/wiki/Forensic_pathology" title="Forensic pathology">Forensic pathology</a></li> <li><a href="/wiki/Funeral_director" title="Funeral director">Funeral director</a></li> <li><a href="/wiki/Mortuary_science" title="Mortuary science">Mortuary science</a></li> <li><a href="/wiki/Cell_death" title="Cell death">Necrobiology</a></li> <li><a href="/wiki/Post-mortem_chemistry" title="Post-mortem chemistry">Post-mortem chemistry</a></li> <li><a href="/wiki/Post-mortem_photography" title="Post-mortem photography">Post-mortem photography</a></li> <li><a href="/wiki/Taphonomy" title="Taphonomy">Taphonomy</a> <ul><li><a href="/wiki/Biostratinomy" title="Biostratinomy">Biostratinomy</a></li></ul></li> <li><a href="/wiki/Thanatology" title="Thanatology">Thanatology</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Apparent_death" title="Apparent death">Apparent death</a></li> <li><a href="/wiki/Chinese_burial_money" title="Chinese burial money">Chinese burial money</a></li> <li><a href="/wiki/Coins_for_the_dead" title="Coins for the dead">Coins for the dead</a></li> <li><a href="/wiki/Dark_tourism" title="Dark tourism">Dark tourism</a></li> <li><a href="/wiki/Darwin_Awards" title="Darwin Awards">Darwin Awards</a></li> <li><a href="/wiki/Death_and_culture" title="Death and culture">Death and culture</a></li> <li><a href="/wiki/Death_anniversary" title="Death anniversary">Death anniversary</a></li> <li><a href="/wiki/Death_anxiety" title="Death anxiety">Death anxiety</a></li> <li><a href="/wiki/List_of_death_deities" title="List of death deities">Death deity</a> <ul><li><a href="/wiki/Personifications_of_death" title="Personifications of death">Personification of death</a></li> <li><a href="/wiki/Dying-and-rising_deity" class="mw-redirect" title="Dying-and-rising deity">Dying-and-rising god</a></li> <li><a href="/wiki/Psychopomp" title="Psychopomp">Psychopomp</a></li></ul></li> <li><a href="/wiki/Extermination_camp" title="Extermination camp">Death camp</a></li> <li><a href="/wiki/Death_drive" title="Death drive">Death drive</a></li> <li><a href="/wiki/Death_education" title="Death education">Death education</a></li> <li><a href="/wiki/Death_from_laughter" title="Death from laughter">Death from laughter</a></li> <li><a href="/wiki/Death_hoax" title="Death hoax">Death hoax</a></li> <li><a href="/wiki/Death_knell" title="Death knell">Death knell</a></li> <li><a href="/wiki/Death_march" title="Death march">Death march</a></li> <li><a href="/wiki/Death_messenger" title="Death messenger">Death messenger</a></li> <li><a href="/wiki/Death_notification" title="Death notification">Death notification</a></li> <li><a href="/wiki/Death_panel" title="Death panel">Death panel</a></li> <li><a href="/wiki/Death_poem" title="Death poem">Death poem</a></li> <li><a href="/wiki/Opisthotonic_death_pose" title="Opisthotonic death pose">Death pose</a></li> <li><a href="/wiki/Death-positive_movement" class="mw-redirect" title="Death-positive movement">Death-positive movement</a></li> <li><a href="/wiki/Death_squad" title="Death squad">Death squad</a></li> <li><a href="/wiki/Death_threat" title="Death threat">Death threat</a></li> <li><a href="/wiki/Death_trajectory" title="Death trajectory">Death trajectory</a></li> <li><a href="/wiki/Dignified_death" title="Dignified death">Dignified death</a></li> <li><a href="/wiki/Extinction" title="Extinction">Extinction</a></li> <li><a href="/wiki/Festival_of_the_Dead" title="Festival of the Dead">Festival of the Dead</a></li> <li><a href="/wiki/Fascination_with_death" title="Fascination with death">Fascination with death</a></li> <li><a href="/wiki/Hierarchy_of_death" title="Hierarchy of death">Hierarchy of death</a></li> <li><a href="/wiki/Homicide" title="Homicide">Homicide</a></li> <li><a href="/wiki/Immortality" title="Immortality">Immortality</a></li> <li><a href="/wiki/Last_rites" title="Last rites">Last rites</a></li> <li><a href="/wiki/Longevity" title="Longevity">Longevity</a></li> <li><a href="/wiki/Martyr" title="Martyr">Martyr</a></li> <li><a href="/wiki/Museum_of_Death" title="Museum of Death">Museum of Death</a></li> <li><a href="/wiki/Necronym" title="Necronym">Necronym</a></li> <li><a href="/wiki/Necrophilia" title="Necrophilia">Necrophilia</a></li> <li><a href="/wiki/Necrophobia" title="Necrophobia">Necrophobia</a></li> <li><a href="/wiki/Philosophy_of_death" title="Philosophy of death">Philosophy of death</a></li> <li><a href="/wiki/Predation" title="Predation">Predation</a></li> <li><a href="/wiki/Sacrifice" title="Sacrifice">Sacrifice</a> <ul><li><a href="/wiki/Human_sacrifice" title="Human sacrifice">human</a></li></ul></li> <li><a href="/wiki/Suicide" title="Suicide">Suicide</a> <ul><li><a href="/wiki/Assisted_suicide" title="Assisted suicide">Assisted suicide</a></li></ul></li> <li><a href="/w/index.php?title=Thanabot&action=edit&redlink=1" class="new" title="Thanabot (page does not exist)">Thanabot</a><span class="noprint" style="font-size:85%; font-style: normal;"> [<a href="https://ca.wikipedia.org/wiki/Grief_bot" class="extiw" title="ca:Grief bot">ca</a>]</span></li> <li><a href="/wiki/Thanatosensitivity" title="Thanatosensitivity">Thanatosensitivity</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><span class="noviewer" typeof="mw:File"><span title="Category"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /></span></span> <a href="/wiki/Category:Death" title="Category:Death">Category</a></li> <li><span class="noviewer" typeof="mw:File"><span title="Outline"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Global_thinking.svg/10px-Global_thinking.svg.png" decoding="async" width="10" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Global_thinking.svg/15px-Global_thinking.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/41/Global_thinking.svg/21px-Global_thinking.svg.png 2x" data-file-width="130" data-file-height="200" /></span></span> <a href="/wiki/Outline_of_death" title="Outline of death">Outline</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Clinical_research_and_experimental_design505" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Medical_research_studies" title="Template:Medical research studies"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Medical_research_studies" title="Template talk:Medical research studies"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Medical_research_studies" title="Special:EditPage/Template:Medical research studies"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Clinical_research_and_experimental_design505" style="font-size:114%;margin:0 4em"><a href="/wiki/Clinical_research" title="Clinical research">Clinical research</a> and <a href="/wiki/Design_of_experiments" title="Design of experiments">experimental design</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Overview</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trial</a> <ul><li><a href="/wiki/Protocol_(science)" title="Protocol (science)">Trial protocols</a></li> <li><a href="/wiki/Adaptive_clinical_trial" class="mw-redirect" title="Adaptive clinical trial">Adaptive clinical trial</a></li></ul></li> <li><a href="/wiki/Academic_clinical_trials" class="mw-redirect" title="Academic clinical trials">Academic clinical trials</a></li> <li><a href="/wiki/Clinical_study_design" title="Clinical study design">Clinical study design</a></li> <li><a href="/wiki/Evidence-based_medicine" title="Evidence-based medicine">Evidence-based medicine</a></li> <li><a href="/wiki/Real_world_evidence" title="Real world evidence">Real world evidence</a></li> <li><a href="/wiki/Patient_and_public_involvement" title="Patient and public involvement">Patient and public involvement</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Scientific_control" title="Scientific control">Controlled study</a><br />(<a href="/wiki/Hierarchy_of_evidence#USA" title="Hierarchy of evidence">EBM I to II-1</a>)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Randomized_controlled_trial" title="Randomized controlled trial">Randomized controlled trial</a> <ul><li><a href="/wiki/Experiment" title="Experiment">Scientific experiment</a></li> <li><a href="/wiki/Blind_experiment" class="mw-redirect" title="Blind experiment">Blind experiment</a></li> <li><a href="/wiki/Open-label_trial" title="Open-label trial">Open-label trial</a></li></ul></li> <li><a href="/wiki/Adaptive_clinical_trial" class="mw-redirect" title="Adaptive clinical trial">Adaptive clinical trial</a> <ul><li><a href="/wiki/Platform_trial" title="Platform trial">Platform trial</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Observational_study" title="Observational study">Observational study</a><br />(<a href="/wiki/Hierarchy_of_evidence#USA" title="Hierarchy of evidence">EBM II-2 to II-3</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cross-sectional_study" title="Cross-sectional study">Cross-sectional study</a> vs. <a href="/wiki/Longitudinal_study" title="Longitudinal study">Longitudinal study</a>, <a href="/wiki/Ecological_study" title="Ecological study">Ecological study</a></li> <li><a href="/wiki/Cohort_study" title="Cohort study">Cohort study</a> <ul><li><a href="/wiki/Retrospective_cohort_study" title="Retrospective cohort study">Retrospective</a></li> <li><a href="/wiki/Prospective_cohort_study" title="Prospective cohort study">Prospective</a></li></ul></li> <li><a href="/wiki/Case%E2%80%93control_study" title="Case–control study">Case–control study</a> (<a href="/wiki/Nested_case%E2%80%93control_study" title="Nested case–control study">Nested case–control study</a>)</li> <li><a href="/wiki/Case_series" title="Case series">Case series</a></li> <li><a href="/wiki/Case_study" title="Case study">Case study</a></li> <li><a href="/wiki/Case_report" title="Case report">Case report</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Outcome_measure" title="Outcome measure">Measures</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Epidemiological_methods#Measures_of_occurrence" class="mw-redirect" title="Epidemiological methods">Occurrence</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Incidence_(epidemiology)" title="Incidence (epidemiology)">Incidence</a>, <a href="/wiki/Cumulative_incidence" class="mw-redirect" title="Cumulative incidence">Cumulative incidence</a>, <a href="/wiki/Prevalence" title="Prevalence">Prevalence</a>, <a href="/wiki/Point_prevalence" class="mw-redirect" title="Point prevalence">Point prevalence</a>, <a href="/wiki/Period_prevalence" class="mw-redirect" title="Period prevalence">Period prevalence</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Epidemiological_methods#Measures_of_association" class="mw-redirect" title="Epidemiological methods">Association</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Risk_difference" title="Risk difference">Risk difference</a>, <a href="/wiki/Number_needed_to_treat" title="Number needed to treat">Number needed to treat</a>, <a href="/wiki/Number_needed_to_harm" title="Number needed to harm">Number needed to harm</a>, <a href="/wiki/Risk_ratio" class="mw-redirect" title="Risk ratio">Risk ratio</a>, <a href="/wiki/Relative_risk_reduction" title="Relative risk reduction">Relative risk reduction</a>, <a href="/wiki/Odds_ratio" title="Odds ratio">Odds ratio</a>, <a href="/wiki/Hazard_ratio" title="Hazard ratio">Hazard ratio</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Population_impact_measure" title="Population impact measure">Population impact</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Attributable_fraction_among_the_exposed" title="Attributable fraction among the exposed">Attributable fraction among the exposed</a>, <a href="/wiki/Attributable_fraction_for_the_population" title="Attributable fraction for the population">Attributable fraction for the population</a>, <a href="/wiki/Preventable_fraction_among_the_unexposed" title="Preventable fraction among the unexposed">Preventable fraction among the unexposed</a>, <a href="/wiki/Preventable_fraction_for_the_population" title="Preventable fraction for the population">Preventable fraction for the population</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Epidemiological_methods#Other_measures" class="mw-redirect" title="Epidemiological methods">Other</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Clinical_endpoint" title="Clinical endpoint">Clinical endpoint</a>, <a href="/wiki/Virulence" title="Virulence">Virulence</a>, <a href="/wiki/Infectivity" title="Infectivity">Infectivity</a>, <a href="/wiki/Mortality_rate" title="Mortality rate">Mortality rate</a>, <a href="/wiki/Morbidity" class="mw-redirect" title="Morbidity">Morbidity</a>, <a class="mw-selflink selflink">Case fatality rate</a>, <a href="/wiki/Specificity_and_sensitivity" class="mw-redirect" title="Specificity and sensitivity">Specificity and sensitivity</a>, <a href="/wiki/Likelihood_ratios_in_diagnostic_testing" title="Likelihood ratios in diagnostic testing">Likelihood-ratios</a>, <a href="/wiki/Pre-_and_post-test_probability" title="Pre- and post-test probability">Pre- and post-test probability</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Trial/test types</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/In_vitro" title="In vitro">In vitro</a></li> <li><a href="/wiki/In_vivo" title="In vivo">In vivo</a></li> <li><a href="/wiki/Animal_testing" title="Animal testing">Animal testing</a></li> <li><a href="/wiki/Animal_testing_on_non-human_primates" title="Animal testing on non-human primates">Animal testing on non-human primates</a></li> <li><a href="/wiki/First-in-man_study" class="mw-redirect" title="First-in-man study">First-in-man study</a></li> <li><a href="/wiki/Multicenter_trial" title="Multicenter trial">Multicenter trial</a></li> <li><a href="/wiki/Seeding_trial" title="Seeding trial">Seeding trial</a></li> <li><a href="/wiki/Vaccine_trial" title="Vaccine trial">Vaccine trial</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Analysis_of_clinical_trials" title="Analysis of clinical trials">Analysis of clinical trials</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Risk%E2%80%93benefit_ratio" title="Risk–benefit ratio">Risk–benefit ratio</a></li> <li><a href="/wiki/Systematic_review" title="Systematic review">Systematic review</a></li> <li><a href="/wiki/Reproducibility" title="Reproducibility">Replication</a></li> <li><a href="/wiki/Meta-analysis" title="Meta-analysis">Meta-analysis</a></li> <li><a href="/wiki/Intention-to-treat_analysis" title="Intention-to-treat analysis">Intention-to-treat analysis</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Interpretation of results</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Selection_bias" title="Selection bias">Selection bias</a></li> <li><a href="/wiki/Survivorship_bias" title="Survivorship bias">Survivorship bias</a></li> <li><a href="/wiki/Correlation_does_not_imply_causation" title="Correlation does not imply causation">Correlation does not imply causation</a></li> <li><a href="/wiki/Null_result" title="Null result">Null result</a></li> <li><a href="/wiki/Sex_as_a_biological_variable" title="Sex as a biological variable">Sex as a biological variable</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><b><a href="/wiki/Category:Clinical_research" title="Category:Clinical research">Category</a></b></li> <li><b><a href="/wiki/Glossary_of_clinical_research" title="Glossary of clinical research">Glossary</a></b></li> <li><b><a href="/wiki/List_of_clinical_research_topics" class="mw-redirect" title="List of clinical research topics">List of topics</a></b></li></ul> </div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" 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