CINXE.COM

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<img class="img-banner" src="https://acdbio.com/sites/default/files/science-banner.jpg"><h1 class="general-title">Wnt / β-Catenin Signaling Pathway</h1><h2 class="banner-sub-title-seo">RNAscope™ Applications</h2></div><div class="content-container container newapplication"><div id="node-112519" class="node node-application" about="/science/applications/research-areas/wnt-%CE%B2-catenin-signaling-pathway" typeof="sioc:Item foaf:Document"><div class="nav-tab-container"><ul class="nav nav-tabs page-tabs application-bxslider" id="myTab"><li class="active"><a href="/science/applications/research-areas/wnt-%CE%B2-catenin-signaling-pathway" class="active">Wnt / β-Catenin Signaling Pathway</a></li><li><a href="/science/applications/research-areas/jak-stat-signaling-pathway">JAK STAT Signaling Pathway</a></li><li><a href="/science/applications/research-areas/akt-signaling-pathway">Akt Signaling Pathway</a></li></ul></div><div class="tab-content"><div id="tab0" class="tab-pane fade in active profile"><h1 class="top-profile">Wnt / β-Catenin Signaling Pathway</h1><div class="sample-image"><div class="loader-image-gallery"></div><div id="film_roll" class="sample-slider"><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Human_Renal%20cell%20carcinoma_CTNNB1_LS%202.5%20Brown.jpg?itok=GTNXQsUn" width="765" height="451" alt="WNT/β-catenin signaling pathway expression analysis RNA Expression CTNNB1 gene human renal carcinoma RNAscope LS 2.5 HD Brown Assay"><p class="slider-below-text"> RNA Expression of CTNNB1 in human renal carcinoma using RNAscope LS 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/8fd7f14ab6d5a84419cb0c04f3ece85b.jpg?itok=39ir5o4t" width="765" height="451" alt="Expression of REST in Human ovarian cancer sample using RNAscope™ 2.5 HD Assay Brown RNA in situ hybridization (ISH)"><p class="slider-below-text"> Expression of REST in Human ovarian cancer sample using RNAscope™ 2.5 HD Assay Brown</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/mSkin_Wnt4-Axin2_CC15-P15_40x.jpg?itok=5Ia_JsmV" width="765" height="451" alt="RNA expression of Wnt4 (green) and Axin2 (red) (WNT B-Catenin signaling pathway) in mouse skin using RNAscope™ Duplex Assay."><p class="slider-below-text"> RNA expression of Wnt4 (green) and Axin2 (red) in mouse skin using RNAscope™ Duplex Assay.</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-REST-ESO-ACD617.jpg?itok=l3rHfm6E" width="765" height="451" alt="RNA expression of REST gene (WNT B-Catenin signaling pathway) in human esophageal cancer sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of REST gene in human esophageal cancer sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-REST-GLI-ACD820_001.jpg?itok=kaPfBwUS" width="765" height="451" alt="RNA expression of REST gene (WNT B-Catenin signaling pathway) in human glioma sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of REST gene in human glioma sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/mPancreas_Wnt4-C1_Brown_0_0.jpg?itok=ABgPPtP6" width="765" height="451" alt="RNAscope™ 2.5 - Mouse Pancreas - Wnt4 (WNT B-Catenin signaling pathway) in situ hybridization"><p class="slider-below-text"> RNAscope™ 2.5 - Mouse Pancreas - Wnt4</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-REST-LIV-ACD654_001.jpg?itok=J4bGfaJa" width="765" height="451" alt="RNA expression of REST gene (WNT B-Catenin signaling pathway) in human liver cancer sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of REST gene in human liver cancer sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-REST-MEN-ACD369.jpg?itok=en2VzwSg" width="765" height="451" alt="RNA expression of REST gene (WNT B-Catenin signaling pathway) in human meningioma sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of REST gene in human meningioma sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-JUN-hs-TMA004-14-OVA-ACD373.jpg?itok=Gg56I-UP" width="765" height="451" alt="RNA expression of JUN gene in human ovarian cancer TMA sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of JUN gene in human ovarian cancer TMA sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-JUN-hs-TMA004-14-ESO-ACD617.jpg?itok=hXQPR0dl" width="765" height="451" alt="RNA expression of JUN gene in human esophageal cancer TMA sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of JUN gene in human esophageal cancer TMA sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-MYC-BLA-ACD097.jpg?itok=KuruHrRL" width="765" height="451" alt="RNA expression of MYC gene (WNT B-Catenin signaling pathway) in human bladder cancer sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of MYC gene in human bladder cancer sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-MYC-CER-ACD234.jpg?itok=nS1YYiYR" width="765" height="451" alt="RNA expression of MYC gene (WNT B-Catenin signaling pathway) in human cervical cancer sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of MYC gene in human cervical cancer sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-MYC-COL-ACD291.jpg?itok=OrrJfbDw" width="765" height="451" alt="RNA expression of MYC gene (WNT B-Catenin signaling pathway) in human colorectal cancer sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of MYC gene in human colorectal cancer sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-MYC-LIV-ACD206.jpg?itok=kOsn3Ckg" width="765" height="451" alt="RNA expression of MYC gene (WNT B-Catenin signaling pathway) in human liver cancer sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of MYC gene in human liver cancer sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-GSK3B-hs-TMA004-12-ESO-ACD617.jpg?itok=1bLRvlT2" width="765" height="451" alt="RNA expression of GSK3B gene (WNT B-Catenin signaling pathway) in human esophageal cancer TMA sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of GSK3B gene in human esophageal cancer TMA sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-GSK3B-hs-TMA004-12-OVA-ACD373.jpg?itok=QuywB2iU" width="765" height="451" alt="RNA expression of GSK3B gene (WNT B-Catenin signaling pathway) in human ovarian cancer TMA sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of GSK3B gene in human ovarian cancer TMA sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-GSK3A-hs-TMA004-11-ESO-ACD617.jpg?itok=JzfUiyDE" width="765" height="451" alt="WNT/β-catenin signaling pathway expression analysis RNA expression of GSK3A in human esophageal cancer RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of GSK3A gene in human esophageal cancer TMA sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/Hs-GSK3A-hs-TMA004-11-OVA-ACD373.jpg?itok=2K_yWIlt" width="765" height="451" alt="RNA expression of GSK3A gene (WNT B-Catenin signaling pathway) in human ovarian cancer TMA sample using RNAscope™ 2.5 HD Brown Assay"><p class="slider-below-text"> RNA expression of GSK3A gene in human ovarian cancer TMA sample using RNAscope™ 2.5 HD Brown Assay</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/mEye_Wnt4_C1_Brown_0_1_1.jpg?itok=TeEUNkdG" width="765" height="451" alt="RNAscope™ 2.5 Brown - Mouse Eye - Wnt4 (WNT B-Catenin signaling pathway)"><p class="slider-below-text"> RNAscope™ 2.5 Brown - Mouse Eye - Wnt4</p></div><div><img src="https://acdbio.com/sites/default/files/styles/film_roll_slider/public/pnas.1601599113fig03_Lim2016_WntGenes_1.jpg?itok=MYCPMhsK" width="765" height="451" alt="WNT B-Catenin Pathway mRNAs"><p class="slider-below-text"> Lim et al (2016) PNAS 16599113 Figure 3</p></div></div><style type="text/css"> .loader-image-gallery { position: absolute; left: 0px; top: 0px; width: 100%; height: 100%; z-index: 9999; background: url('/sites/default/files/loading_apple.gif') 50% 35% no-repeat rgb(249,249,249); background-size: 100px; opacity: .8; } .sample-image { position: relative; } </style> <script type="text/javascript"> jQuery(document).ready(function($) { // $('#film_roll').hide(); function preloader(){ $('.loader-image-gallery').hide(); $('#film_roll').show(); } window.onload = preloader; }); </script> </div><div class="profile-content application_node_112519"><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p><img alt="WNT B-Catenin Pathway" src="/sites/default/files/WNT%20Image.JPG" style="margin: 0px auto; width: 382px; height: 493px; display: block;" /></p><p> </p><h4><strong>Pathway information and image are provided courtesy of <a href="https://www.rndsystems.com/">R&D Systems, a Bio-Techne Brand.</a> A high resolution and interactive image of this pathway is available on<a href="https://www.rndsystems.com/pathways/wnt-signaling-pathways-beta-catenin-dependent-wnt-signaling"> their website</a>. </strong></h4><p> </p><div class="show-hide"><div class="r-show"><p>WNT/ β-catenin signaling is involved in a variety of cellular processes related to development, including differentiation, homeostasis, genetic stability, and proliferation. Aberrant signaling of the WNT/ β-catenin pathway is also associated with many types of cancer. Secreted proteins, like WNTs, are challenging for antibody detection using immunohistochemistry (IHC) and require alternative methods to identify their cellular localization. The RNAscope™ <em>in situ</em> hybridization (ISH) assay provides single-cell gene expression resolution with spatial and morphological context.</p><p> </p><p><strong>The RNAscope™ ISH assay is ideal for expression analysis of the WNT/ </strong>β<strong>-catenin signaling pathway:</strong></p><p> </p><p><strong>Proven ultra-high sensitivity for the detection of secreted proteins - </strong>Accurate detection of secreted proteins like WNTs require highly sensitive assays. RNAscope ISH, known for its ultra-sensitivity, has been referenced in over 40 WNT signaling pathway publications.</p><p><strong>ANY Gene and WNT family member - </strong>When analyzing this pathway, researchers typically examine the expression of multiple WNT genes. RNAscope probes can be designed for virtually ANY GENE, enabling researchers to apply a single detection method across all members of the WNT family as well as other genes in the pathway.</p><p><strong>ANY Species and model systems - </strong>Studies of the WNT/ β-catenin pathway are often performed in human and also in model organisms such as mouse, <em>C. elegans</em>, Xenopus, Zebrafish and Drosophila. RNAscope probes can be designed for virtually ANY SPECIES so examination of genes in the WNT/ β-catenin pathway across multiple model organisms can be conducted seamlessly.</p><p><strong>RNAscope™ WISH in embryos</strong>—The <a href="https://acdbio.com/innovations-rnascope">wholemount <em>in situ</em> hybridization (WISH) methodology in zebrafish</a> with the RNAscope assay was published in 2014 by <a href="http://bmcbiol.biomedcentral.com/articles/10.1186/s12915-014-0055-7">Gross-Thebing, <em>et al.</em></a>. This customer-derived innovation enables the study of the WNT/β-catenin pathway in wholemount embryos from species such as Xenopus, Zebrafish and Drosophila.</p><p><strong>BaseScope™ Assay and WNT/ </strong><strong>β-catenin pathway mutations - </strong>ACD’s recently introduced BaseScope Assay enables detection of splice variants, mutations and more within the tissue environment. This assay offers researchers a unique method to examine mutations in WNT pathway genes <em>in situ</em> and more thoroughly understand their roles in developmental defects. </p></div></div></div></div></div><div class="view view-application view-id-application view-display-id-block_8 view-dom-id-3958abb1ae9f29550e0832f45a3355ff"></div><div class="view view-application view-id-application view-display-id-block_9 view-dom-id-334d2dbc39e5e622f5471937dc3a0dbd"><div class="view-content"><style type="text/css"> .view-id-application.view-display-id-block_9 .row.immuno-watch { margin-top: 15px; margin-bottom: 15px; } </style></div></div></div><div class="sample-image"><div class="profile-bottom"></div></div><div id="animal-models"><div class="immuno-content animalmodels-bottom-wrap"><div class="animalmodels-bottom"><div class="container"><div class="row viruses"><div class="col-lg-12 col-md-12 col-sm-12 col-xs-12"><div class="sec-title" style="border-bottom-color: currentColor; border-bottom-width: medium; border-bottom-style: none;">Wnt / β-Catenin Signaling Pathway Genes</div><p>(Click on the name to access corresponding RNAscope™ Catalog Probes)</p><p> </p><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12"><ul><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT1">WNT1</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT2">WNT2</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT2B">WNT2B</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT3">WNT3</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT3A">WNT3A</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT4">WNT4</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT5A">WNT5A</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT5B">WNT5B</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT6">WNT6</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT7A">WNT7A</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT7B">WNT7B</a></li><li> </li></ul></div><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12"><ul><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT8A**">WNT8A</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT8B**">WNT8B</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT9A">WNT9A</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT9B">WNT9B</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT10A">WNT10A</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT10B">WNT10B</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT11">WNT11</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WNT16">WNT16</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/AXIN2">AXIN2</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/CALM1">CALM1</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/CTNNB1">CTNNB1</a> (B-catenin)</li></ul></div><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12"><ul><li><a href="/search/site/%252A%252A/cms/probes/gene/DVL1">DVL1</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/FZD4">FZD4</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/FZD5">FZD5</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/FZD7">FZD7</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/FZD8">FZD8</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/FZD9">FZD9</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/GSK3A">GSK3A</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/GSK3B">GSK3B</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/JUN">JUN</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/LGR4">LGR4</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/LGR5">LGR5</a></li></ul></div><div class="col-lg-3 col-md-3 col-sm-3 col-xs-12"><ul><li><a href="/search/site/%252A%252A/cms/probes/gene/LRP5">LRP5</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/LRP6">LRP6</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/MAP3K7">MAP3K7(TAK1)</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/MYC">MYC</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/PTK7">PTK7</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/REST">REST</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/ROR1">ROR1</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/ROR2">ROR2</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/WIF1">WIF1</a></li><li><a href="/search/site/%252A%252A/cms/probes/gene/ZNRF3">ZNRF3</a></li></ul></div><div class="clear"> </div><p> </p><p>** If your gene of interest is not listed or is listed above but there is no catalog probe targeting your species of choice,  ACD can design and manufacture new probes in 2 weeks.</p><p><a class="blue-link" href="/target-probes-made-order">Request New Probes</a></p><p> </p></div></div></div></div></div></div><div class="gene-search"><div class="profile-bottom"><h2>Search RNAscope™ ISH Catalog Target Probes:</h2><p>ACD's probe list is continuously evolving, adding new probes frequently to our catalog, enter your gene of interest to see more.</p><div class="gene-search-form search-app-form"> <input type="hidden" class="search-app-url" value=""/> <input class="search-app-text" type="text"/> <input type="submit" class="search-app-submit" value="search"/><div class="clear"></div></div><div class="download-pdf"></div></div></div><div class="spotlight"><div class="profile-bottom publication"><h2>Related Publications</h2><p>There are over 40 publications citing both the WNT gene and RNAscope ISH.</p><div class="download-pdf"> <a href="https://acdbio.com/science/scientific-resources/publications/wnt"> Read Abstracts Here </a></div></div></div></div></div></div></div></div> <script type="text/javascript"> jQuery(document).ready(function($) { var windowsize = $(window).width(); 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more details in the Contact Sales form below</p></div><div class="needhelp-tab"><div class="nav-tab-container"><ul class="nav nav-tabs page-tabs" id="help-tictab"><li class="active"><a data-toggle="tab" href="#contactsales">Contact Sales</a></li><li><a data-toggle="tab" href="#contactsupport">Contact Support</a></li><li><a data-toggle="tab" href="#contactpharma">Contact Services</a></li><li><a data-toggle="tab" href="#contactinfo">Offices</a></li></ul></div><div class="tab-content"><div class="needhelp-tab-container tab-pane fade in active" id="contactsales"><div class="supportform-con"><div class="contact-tab-form supportform-con"> <script src="//info.bio-techne.com/js/forms2/js/forms2.min.js"></script> <form id="mktoForm_9816"></form> <script>MktoForms2.loadForm("//info.bio-techne.com", "584-XSF-168", 9816);</script> </div></div></div><div class="needhelp-tab-container tab-pane fade" id="contactsupport"><div class="supportform-con"><form action="https://proteinsimple--obtfull.my.salesforce.com/servlet/servlet.WebToCase?encoding=UTF-8" id="web-to-case1" method="POST"><div class="row"><div class="col-md-6"> <label for="fname">First Name</label> <input id="fname" maxlength="80" name="fname" size="20" type="text"></div><div class="col-md-6"> <label for="lname">Last Name</label> <input id="lname" maxlength="80" name="lname" size="20" type="text"></div></div><div class="row"><div class="col-md-6"> <label for="email">Email</label> <input id="email" maxlength="80" name="email" size="20" type="text"></div><div class="col-md-6"> <label for="phone">Phone</label> <input id="phone" maxlength="40" name="phone" size="20" type="text"></div></div><div class="row"><div class="col-md-6"> <label for="company">Institution / Company</label> <input id="company" maxlength="80" name="company" size="20" type="text"></div></div><div class="row"><div class="col-md-12"> <label for="description">Message</label> <textarea name="description"></textarea> </div></div><div class="row captcha"><div class="col-lg-12 col-md-12 col-sm-12 col-xs-12"> <label>Type the characters that you see in the picture below</label> <input type="text" id="PageCaseCaptcha" disabled /> <a class="btnrefresh" onclick="DrawCaptcha();"></a></div></div><div class="row captcha"><div class="col-lg-12 col-md-12 col-sm-12 col-xs-12"> <input type="text" class="case_captcha" id="PageCaseInput" name="case_captcha"/><div id="pagecasecaptcha-error"></div></div></div> <input type="submit" name="submit" style="float:left;" onclick="ValidCaptcha('pagecase');"><div class="clear"></div></form></div></div><div class="needhelp-tab-container tab-pane fade" id="contactinfo"><div class="supportform-con contact-info"><div class="row"><h3>Advanced Cell Diagnostics</h3><p>Our new headquarters office starting May 2016:</p><p>7707 Gateway Blvd. <br />Newark, CA 94560<br />Toll Free: 1 (877) 576-3636<br />Phone: (510) 576-8800<br />Fax: (510) 576-8798</p></div><div class="row"><p> </p><div class="row"><h3>Bio-Techne</h3><p>19 Barton Lane <br />Abingdon Science Park<br />Abingdon<br />OX14 3NB<br />United Kingdom<br />Phone 2: +44 1235 529449<br />Fax: +44 1235 533420</p><p> </p></div><div class="row"><h3>Advanced Cell Diagnostics China</h3><p>20F, Tower 3,<br />Raffles City Changning Office,<br />1193 Changning Road, Shanghai 200051</p><p>021-52293200<br /><a href="mailto:info.cn@bio-techne.com">info.cn@bio-techne.com</a><br />Web: <a href="http://www.acdbio.com/cn">www.acdbio.com/cn</a></p></div><div class="row"><p>For general information: <a href="mailto:Info.ACD@bio-techne.com">Info.ACD@bio-techne.com</a><br />For place an order: <a href="mailto:order.ACD@bio-techne.com">order.ACD@bio-techne.com</a><br />For product support: <a href="mailto:support.ACD@bio-techne.com">support.ACD@bio-techne.com</a><br />For career opportunities: <a href="mailto:hr.ACD@bio-techne.com">hr.ACD@bio-techne.com</a></p></div></div><div class="row" style="border-bottom: none;"><div class="col-md-6"> <a href="/about/distributors" class="meet-out-sales-team" title="See Distributors">See Distributors</a></div></div></div></div><div class="needhelp-tab-container tab-pane fade" id="contactpharma"><div class="supportform-con"><div class="contact-tab-form supportform-con"><form id="mktoForm_9817"></form> <script>MktoForms2.loadForm("//info.bio-techne.com", "584-XSF-168", 9817);</script> </div></div></div></div></div></div></div></div></div></div> <script type="text/javascript"> jQuery(document).ready(function($) { $("#web-to-case1").validate({ // Specify the validation rules rules: { fname: "required", lname: "required", phone:"required", email: { required: true, email: true }, company: "required", case_captcha: "required" }, // Specify the validation error messages messages: { fname: "Please enter your First Name", lname: "Please enter your Last Name", email: "Please enter your email address", phone: "Please enter your 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