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KEGG ORTHOLOGY: K18076
<!doctype html> <html><head> <title>KEGG ORTHOLOGY: K18076</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1732411411"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1732411411"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1732411411" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « '+hide; 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} } } function Link_XtrctSeq2(form) { var dna_from; var dna_to; var dna_len; var plus_up = Number(form.XtrctSeq_UP.value) ; var plus_down = Number(form.XtrctSeq_DOWN.value); var vector = Number(form.VECTOR.value); var org = form.ORG.value; var chr = form.CHR.value; var kid = form.KEGGID.value; var url; if (plus_up == 0 && plus_down == 0) { url = "/entry/-f+-n+n+" + kid; } else { if (vector == 1) { dna_from = Number(form.FROM.value) - plus_up; dna_to = Number(form.TO.value) + plus_down; } else { dna_from = Number(form.FROM.value) - plus_down; dna_to = Number(form.TO.value) + plus_up; } url = "/dbget-bin/cut_sequence_genes.pl?FROM=" + dna_from + "&TO=" + dna_to +"&VECTOR=" + vector + "&ORG=" + org; if (chr) url += "&CHR=" + chr; } //window.open( url, "_self" ); location.href = url; } function go_taxonomy(form,params){ for(var key in params){ if(form[key]){ form.setAttribute(key,params[key]); } else{ var obj = document.createElement('input'); obj.setAttribute('type','hidden'); obj.setAttribute('name',key); obj.setAttribute('value',params[key]); form.appendChild(obj); } } form.submit(); } window.onload=function(){window.focus();init();}; //---> </script> </head> <body> <div> <table border=0 cellpadding=0 cellspacing=0><tr><td> <table border=0 cellpadding=0 cellspacing=0 width="650"><tr><td width=70><a href="/kegg/kegg2.html"><img align="middle" alt="KEGG" border=0 src="/Fig/bget/kegg4.gif"></a></td><td> </td><td><a name="orthology:K18076"></a><font class="title4">ORTHOLOGY: K18076</font></td><td class="tar vbot"><button class="btn" onclick="javascript:void(window.open('/kegg/document/help_bget_ko.html','KEGG_Help','toolbar=no,location=no,directories=no,width=720,height=640,resizable=yes,scrollbars=yes'));return false;">Help</button></td></tr></table><form method="post" action="/kegg-bin/search_htext" enctype="application/x-www-form-urlencoded" id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr4 w1"> <table width="650" class="w2"> <tr><th class="th40 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td40 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">K18076 KO <br> </span></code></td></tr></table></td></tr> <tr><th class="th41 deft tal vtop"><span class="nowrap">Symbol</span></th> <td class="td41 defd"><div class="cel">tphB<br> </div></td></tr> <tr><th class="th40 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td40 defd"><div class="cel"><div class="cel">1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase [EC:<a href="/entry/1.3.1.53">1.3.1.53</a>]<br> </div></div></td></tr> <tr><th class="th41 deft tal vtop"><span class="nowrap">Pathway</span></th> <td class="td41 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map00624+K18076">map00624</a> </span></td><td>Polycyclic aromatic hydrocarbon degradation</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01100+K18076">map01100</a> </span></td><td>Metabolic pathways</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01120+K18076">map01120</a> </span></td><td>Microbial metabolism in diverse environments</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01220+K18076">map01220</a> </span></td><td>Degradation of aromatic compounds</td></tr></table></td></tr> <tr><th class="th40 deft tal vtop"><span class="nowrap">Module</span></th> <td class="td40 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/module/M00624+K18076">M00624</a> </span></td><td>Terephthalate degradation, terephthalate => 3,4-dihydroxybenzoate</td></tr></table></td></tr> <tr><th class="th41 deft tal vtop"><span class="nowrap">Reaction</span></th> <td class="td41 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/R01633">R01633</a> </span></td><td>(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase</td></tr></table></td></tr> <tr><th class="th40 deft tal vtop"><span class="nowrap">Brite</span></th> <td class="td40 defd"><div class="cel"><span class="nowrap">KEGG Orthology (KO) [BR:<a href="/brite/ko00001+K18076">ko00001</a>]<br> 09100 Metabolism<br> 09111 Xenobiotics biodegradation and metabolism<br> 00624 Polycyclic aromatic hydrocarbon degradation<br> K18076 tphB; 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase<br> Enzymes [BR:<a href="/brite/ko01000+K18076">ko01000</a>]<br> 1. Oxidoreductases<br> 1.3 Acting on the CH-CH group of donors<br> 1.3.1 With NAD+ or NADP+ as acceptor<br> 1.3.1.53 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase<br> K18076 tphB; 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase<br> Dioxygenases [<a href="/kegg/annotation/br01602.html?id=K18076">br01602.html</a>]<br> Dioxygenases in aromatic ring cleavage<br> K18076<br> </span></div><button class="btn" onclick="location.href='/kegg-bin/search_brite?option=-a&search_string=K18076';return false;">BRITE hierarchy</button></td></tr> <tr><th class="th41 deft tal vtop"><span class="nowrap">Other DBs</span></th> <td class="td41 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">GO: </span></td><td><a href="http://amigo.geneontology.org/amigo/term/GO:0047120">0047120</a></td></tr></table></td></tr> <tr><th class="th40 deft tal vtop"><span class="nowrap">Genes</span></th> <td class="td40 defd"><style>.g1{display:none;}</style><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">RHOB: </span></td><td><a href="/entry/rhob:HTY51_11720">HTY51_11720</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">VPD: </span></td><td><a href="/entry/vpd:VAPA_2c09680">VAPA_2c09680</a>(pdxA)</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">CTT: </span></td><td><a href="/entry/ctt:CtCNB1_1495">CtCNB1_1495</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">CTES: </span></td><td><a href="/entry/ctes:O987_22465">O987_22465</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">RTA: </span></td><td><a href="/entry/rta:Rta_16730">Rta_16730</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">RTEA: </span></td><td><a href="/entry/rtea:HK414_12000">HK414_12000</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">HYR: </span></td><td><a href="/entry/hyr:BSY239_2687">BSY239_2687</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">HYB: </span></td><td><a href="/entry/hyb:Q5W_19725">Q5W_19725</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">HTN: </span></td><td><a href="/entry/htn:KI616_03575">KI616_03575</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">HCZ: </span></td><td><a href="/entry/hcz:G9Q37_15440">G9Q37_15440</a></td></tr></table><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">HYY: </span></td><td><a href="/entry/hyy:JNX00_14770">JNX00_14770</a></td></tr></table></div><a href="javascript:void(0)" onclick="javascript:toggleField(this,"g1","show all","hide")"> » show all</a><br> <button class="btn" onclick="location.href='/kegg-bin/show_taxonomy?ko=K18076';return false;">Taxonomy</button><button class="btn" onclick="location.href='/kegg-bin/uniprot_list?ko=K18076';return false;">UniProt</button></td></tr> <tr><th class="th41 deft tal vtop"><span class="nowrap">Reference</span></th> <td class="td41 defd"><div class="cel">PMID:<a href="https://www.ncbi.nlm.nih.gov/pubmed/16517628">16517628</a></div></td></tr> <tr><th class="th40 rept tal vtop"><span class="nowrap"> Authors</span></th> <td class="td40 repd"><div class="cel">Sasoh M, Masai E, Ishibashi S, Hara H, Kamimura N, Miyauchi K, Fukuda M</div></td></tr> <tr><th class="th41 rept tal vtop"><span class="nowrap"> Title</span></th> <td class="td41 repd"><div class="cel">Characterization of the terephthalate degradation genes of Comamonas sp. strain E6.</div></td></tr> <tr><th class="th40 rept tal vtop"><span class="nowrap"> Journal</span></th> <td class="td40 repd"><div class="cel">Appl Environ Microbiol 72:1825-32 (2006)<br>DOI:<a href="https://doi.org/10.1128/AEM.72.3.1825-1832.2006">10.1128/AEM.72.3.1825-1832.2006</a></div></td></tr> <tr><th class="th41 rept tal vtop"><span class="nowrap"> Sequence</span></th> <td class="td41 repd"><div class="cel">[ctt:<a href="/entry/ctt:CtCNB1_1495">CtCNB1_1495</a>]</div></td></tr> <tr><th class="th40 deft tal vtop"><span class="nowrap">Reference</span></th> <td class="td40 defd"><div class="cel">PMID:<a href="https://www.ncbi.nlm.nih.gov/pubmed/8565920">8565920</a></div></td></tr> <tr><th class="th41 rept tal vtop"><span class="nowrap"> Authors</span></th> <td class="td41 repd"><div class="cel">Wang YZ, Zhou Y, Zylstra GJ</div></td></tr> <tr><th class="th40 rept tal vtop"><span class="nowrap"> Title</span></th> <td class="td40 repd"><div class="cel">Molecular analysis of isophthalate and terephthalate degradation by Comamonas testosteroni YZW-D.</div></td></tr> <tr><th class="th41 rept tal vtop"><span class="nowrap"> Journal</span></th> <td class="td41 repd"><div class="cel">Environ Health Perspect 103 Suppl 5:9-12 (1995)<br>DOI:<a href="https://doi.org/10.1289/ehp.95103s49">10.1289/ehp.95103s49</a></div></td></tr> <tr><th class="th40 rept tal vtop"><span class="nowrap"> Sequence</span></th> <td class="td40 repd"><div class="cel">[ctt:<a href="/entry/ctt:CtCNB1_1495">CtCNB1_1495</a>]</div></td></tr> <tr><th class="th41 deft tal vmid"><span class="nowrap">LinkDB</span></th> <td class="td41 defd"><button class="btn" onclick="location.href='https://www.genome.jp/dbget-bin/get_linkdb?orthology+K18076';return false;">All DBs</button></td></tr> </table></td></tr></table> <br></td></tr></table> <a href="/dbget/">DBGET</a> integrated database retrieval system</div> </body> </html>