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Prednisolone Research Papers - Academia.edu
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overflow: hidden; text-overflow: ellipsis; -webkit-line-clamp: 3; -webkit-box-orient: vertical; }</style><div class="col-xs-12 clearfix"><div class="u-floatLeft"><h1 class="PageHeader-title u-m0x u-fs30">Prednisolone</h1><div class="u-tcGrayDark">19 Followers</div><div class="u-tcGrayDark u-mt2x">Recent papers in <b>Prednisolone</b></div></div></div></div></div></div><div class="TabbedNavigation"><div class="container"><div class="row"><div class="col-xs-12 clearfix"><ul class="nav u-m0x u-p0x list-inline u-displayFlex"><li class="active"><a href="https://www.academia.edu/Documents/in/Prednisolone">Top Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Prednisolone/MostCited">Most Cited Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Prednisolone/MostDownloaded">Most Downloaded Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Prednisolone/MostRecent">Newest Papers</a></li><li><a class="" href="https://www.academia.edu/People/Prednisolone">People</a></li></ul></div><style type="text/css">ul.nav{flex-direction:row}@media(max-width: 567px){ul.nav{flex-direction:column}.TabbedNavigation li{max-width:100%}.TabbedNavigation li.active{background-color:var(--background-grey, #dddde2)}.TabbedNavigation li.active:before,.TabbedNavigation li.active:after{display:none}}</style></div></div></div><div class="container"><div class="row"><div class="col-xs-12"><div class="u-displayFlex"><div class="u-flexGrow1"><div class="works"><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_49272850" data-work_id="49272850" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/49272850/Resolution_of_Eosinophilic_Peritonitis_with_Oral_Prednisolone_in_a_Child_Receiving_Peritoneal_Dialysis">Resolution of Eosinophilic Peritonitis with Oral Prednisolone in a Child Receiving Peritoneal Dialysis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Editor: Eosinophilic peritonitis is defined as the presence of an absolute eosinophil count exceeding 30 per cubic millimeter of dialysis fluid in patients receiving mainte-nance peritoneal dialysis (PD) (1,2). In adult patients, the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_49272850" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Editor: Eosinophilic peritonitis is defined as the presence of an absolute eosinophil count exceeding 30 per cubic millimeter of dialysis fluid in patients receiving mainte-nance peritoneal dialysis (PD) (1,2). In adult patients, the incidence has been reported to range from 16% – 30% in intermittent PD to as high as 60% in continuous ambulatory PD (CAPD) (1,2). It usually occurs within the first 3 months after dialysis initiation, although it has been reported to occur even later (2). A 7-year-old boy with end-stage renal disease second-ary to focal segmental glomerulosclerosis who had been on automated PD (APD) for 3 months was admitted to our hospital for evaluation of a malfunctioning PD catheter and a history of turbid peritoneal effluent. We observed no fever, rash, or abdominal pain, and no past history of atopy or allergies. Physical examination was unre-markable. Radiography of the abdomen showed upward migration of the distal part of the catheter. 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In adult patients, the incidence has been reported to range from 16% – 30% in intermittent PD to as high as 60% in continuous ambulatory PD (CAPD) (1,2). It usually occurs within the first 3 months after dialysis initiation, although it has been reported to occur even later (2). A 7-year-old boy with end-stage renal disease second-ary to focal segmental glomerulosclerosis who had been on automated PD (APD) for 3 months was admitted to our hospital for evaluation of a malfunctioning PD catheter and a history of turbid peritoneal effluent. We observed no fever, rash, or abdominal pain, and no past history of atopy or allergies. Physical examination was unre-markable. Radiography of the abdomen showed upward migration of the distal part of the catheter. Intravenous first-generat...","downloadable_attachments":[{"id":67656560,"asset_id":49272850,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":81314331,"first_name":"Burhan","last_name":"Edrees","domain_name":"independent","page_name":"BurhanEdrees","display_name":"Burhan Edrees","profile_url":"https://independent.academia.edu/BurhanEdrees?f_ri=168358","photo":"https://0.academia-photos.com/81314331/77890102/66433615/s65_burhan.edrees.jpeg"}],"research_interests":[{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=168358","nofollow":false},{"id":168358,"name":"Prednisolone","url":"https://www.academia.edu/Documents/in/Prednisolone?f_ri=168358","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=168358","nofollow":false},{"id":447741,"name":"Peritoneal 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class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Formulation of a new Prednisolone acetate (1%) ophthalmic suspension to obtain a better contactibility of the drug at the site of action. The formulation was evaluated and optimized based on physiological, physicochemical and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_12640201" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Formulation of a new Prednisolone acetate (1%) ophthalmic suspension to obtain a better contactibility of the drug at the site of action. The formulation was evaluated and optimized based on physiological, physicochemical and pharmaceutical parameters and prepared aseptically, keeping particle size between 1-3 microm, while viscosity enhancer, preservative, chelating agent were used to increase the transient residence time, antimicrobial preservation respectively. Isotonicity of the formulation was maintained. Buffering agents used were having buffering capacity NMT 0.05%. pH adjusted at which Prednisolone acetate was stable. The finished product subjected to stress conditions to check the physical stability of the formulation. The formulation was packed in LDPE plastic vials, and subjected to accelerated stability studies at 40 degrees C and the kinetic and predictive method was employed for the determination of degradation rate constant and shelf life. The results showed that the ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12640201" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7c87a55c0aa9e9d201261b9940e02c0d" rel="nofollow" data-download="{"attachment_id":46033377,"asset_id":12640201,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46033377/download_file?st=MTczMzM2OTk2Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31618849" href="https://independent.academia.edu/MuhammadAkramPhd">Muhammad Akram Phd</a><script data-card-contents-for-user="31618849" type="text/json">{"id":31618849,"first_name":"Muhammad","last_name":"Akram Phd","domain_name":"independent","page_name":"MuhammadAkramPhd","display_name":"Muhammad Akram Phd","profile_url":"https://independent.academia.edu/MuhammadAkramPhd?f_ri=168358","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12640201 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12640201"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12640201, container: ".js-paper-rank-work_12640201", }); 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The formulation was evaluated and optimized based on physiological, physicochemical and pharmaceutical parameters and prepared aseptically, keeping particle size between 1-3 microm, while viscosity enhancer, preservative, chelating agent were used to increase the transient residence time, antimicrobial preservation respectively. Isotonicity of the formulation was maintained. Buffering agents used were having buffering capacity NMT 0.05%. pH adjusted at which Prednisolone acetate was stable. The finished product subjected to stress conditions to check the physical stability of the formulation. The formulation was packed in LDPE plastic vials, and subjected to accelerated stability studies at 40 degrees C and the kinetic and predictive method was employed for the determination of degradation rate constant and shelf life. 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href="https://www.academia.edu/21449807/Efficacy_and_safety_of_intravenous_cyclophosphamide_pulse_therapy_with_oral_prednisolone_in_the_treatment_of_interstitial_lung_disease_with_systemic_sclerosis_4_year_follow_up">Efficacy and safety of intravenous cyclophosphamide pulse therapy with oral prednisolone in the treatment of interstitial lung disease with systemic sclerosis: 4-year follow-up</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/21449807" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ff1cb7d4b5ed4332a90bdd8f3c67bb7a" rel="nofollow" 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studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=168358","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="137516" href="https://www.academia.edu/Documents/in/Follow-up_studies">Follow-up studies</a>, <script data-card-contents-for-ri="137516" type="text/json">{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=168358","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="168358" href="https://www.academia.edu/Documents/in/Prednisolone">Prednisolone</a><script data-card-contents-for-ri="168358" type="text/json">{"id":168358,"name":"Prednisolone","url":"https://www.academia.edu/Documents/in/Prednisolone?f_ri=168358","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=21449807]'), work: {"id":21449807,"title":"Efficacy and safety of intravenous cyclophosphamide pulse therapy with oral prednisolone in the treatment of interstitial lung disease with systemic sclerosis: 4-year follow-up","created_at":"2016-02-02T03:23:39.379-08:00","url":"https://www.academia.edu/21449807/Efficacy_and_safety_of_intravenous_cyclophosphamide_pulse_therapy_with_oral_prednisolone_in_the_treatment_of_interstitial_lung_disease_with_systemic_sclerosis_4_year_follow_up?f_ri=168358","dom_id":"work_21449807","summary":null,"downloadable_attachments":[{"id":41882894,"asset_id":21449807,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":42525721,"first_name":"Takahisa","last_name":"Gono","domain_name":"independent","page_name":"TakahisaGono","display_name":"Takahisa Gono","profile_url":"https://independent.academia.edu/TakahisaGono?f_ri=168358","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":12426,"name":"Treatment 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Practice","url":"https://www.academia.edu/Documents/in/Small_Animal_Practice?f_ri=168358"},{"id":1293308,"name":"Glucocorticoids","url":"https://www.academia.edu/Documents/in/Glucocorticoids?f_ri=168358"},{"id":1938454,"name":"Adverse effects","url":"https://www.academia.edu/Documents/in/Adverse_effects?f_ri=168358"},{"id":1938849,"name":"Arteritis","url":"https://www.academia.edu/Documents/in/Arteritis?f_ri=168358"},{"id":2483297,"name":"Immunoglobulin A","url":"https://www.academia.edu/Documents/in/Immunoglobulin_A?f_ri=168358"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_49397772" data-work_id="49397772" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/49397772/Corticosteroid_Therapy_for_Patients_With_Acute_Exacerbations_of_Chronic_Obstructive_Pulmonary_Disease">Corticosteroid Therapy for Patients With Acute Exacerbations of Chronic Obstructive Pulmonary Disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective: To determine whether systemic corticoste- roids are of benefit to patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). Methods: An English-language search of MEDLINE (1966 to February 2002) and the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_49397772" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective: To determine whether systemic corticoste- roids are of benefit to patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). Methods: An English-language search of MEDLINE (1966 to February 2002) and the Cochrane Library and a bibliographic review was performed to identify pub- lished clinical trials of systemic corticosteroid adminis- tration in acute exacerbations of COPD. All relevant En-</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/49397772" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b3aedeb4cf2e3d319c5613556ddd6e37" rel="nofollow" data-download="{"attachment_id":67762042,"asset_id":49397772,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67762042/download_file?st=MTczMzM2OTk2Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="2721501" href="https://utoronto.academia.edu/KennethChapman">Kenneth Chapman</a><script data-card-contents-for-user="2721501" type="text/json">{"id":2721501,"first_name":"Kenneth","last_name":"Chapman","domain_name":"utoronto","page_name":"KennethChapman","display_name":"Kenneth Chapman","profile_url":"https://utoronto.academia.edu/KennethChapman?f_ri=168358","photo":"https://0.academia-photos.com/2721501/5784728/6574075/s65_kenneth.chapman.jpg"}</script></span></span></li><li class="js-paper-rank-work_49397772 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="49397772"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 49397772, container: ".js-paper-rank-work_49397772", }); 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All relevant En-","downloadable_attachments":[{"id":67762042,"asset_id":49397772,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":2721501,"first_name":"Kenneth","last_name":"Chapman","domain_name":"utoronto","page_name":"KennethChapman","display_name":"Kenneth Chapman","profile_url":"https://utoronto.academia.edu/KennethChapman?f_ri=168358","photo":"https://0.academia-photos.com/2721501/5784728/6574075/s65_kenneth.chapman.jpg"}],"research_interests":[{"id":3979,"name":"English language","url":"https://www.academia.edu/Documents/in/English_language?f_ri=168358","nofollow":false},{"id":4531,"name":"Clinical 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type="text/json">{"id":88062,"name":"Vasculitis","url":"https://www.academia.edu/Documents/in/Vasculitis?f_ri=168358","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="168358" href="https://www.academia.edu/Documents/in/Prednisolone">Prednisolone</a>, <script data-card-contents-for-ri="168358" type="text/json">{"id":168358,"name":"Prednisolone","url":"https://www.academia.edu/Documents/in/Prednisolone?f_ri=168358","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="204350" href="https://www.academia.edu/Documents/in/Anti-inflammatory_agents">Anti-inflammatory agents</a><script data-card-contents-for-ri="204350" type="text/json">{"id":204350,"name":"Anti-inflammatory agents","url":"https://www.academia.edu/Documents/in/Anti-inflammatory_agents?f_ri=168358","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=34084681]'), work: 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href="https://www.academia.edu/16415950/Post_transplant_EBV_related_lymphoproliferative_disorder_complicating_umbilical_cord_blood_transplantation_in_patients_of_adrenoleukodystrophy">Post-transplant EBV-related lymphoproliferative disorder complicating umbilical cord blood transplantation in patients of adrenoleukodystrophy</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16415950" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c36b747d06c071fa13dbd3f4e891e791" rel="nofollow" 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A case report</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We present an extreme case of Toxic Epidermal Necrolysis, which corresponds to a severe form of Stevens Johnson Syndrome. This is a potentially fatal immune reaction that affects skin and mucosa, producing blisters and sloughing of the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_26811799" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We present an extreme case of Toxic Epidermal Necrolysis, which corresponds to a severe form of Stevens Johnson Syndrome. This is a potentially fatal immune reaction that affects skin and mucosa, producing blisters and sloughing of the epithelium. Severe sequelae, including blindness, hearing loss, tooth malformation and esophageal destruction are seen in this case.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/26811799" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="110b7c62d86a6f7d59fd7d2d63780d8a" rel="nofollow" data-download="{"attachment_id":47084696,"asset_id":26811799,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47084696/download_file?st=MTczMzM2OTk2Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="50810217" href="https://independent.academia.edu/VelezInes">Ines Velez</a><script data-card-contents-for-user="50810217" type="text/json">{"id":50810217,"first_name":"Ines","last_name":"Velez","domain_name":"independent","page_name":"VelezInes","display_name":"Ines Velez","profile_url":"https://independent.academia.edu/VelezInes?f_ri=168358","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-26811799">+2</span><div class="hidden js-additional-users-26811799"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/LinaMejia11">Lina Mejia</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/AnaOspina13">Ana Ospina</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-26811799'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-26811799').html(); 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Therapy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">ABSTRACT: We report the case of drug-induced, acrolocalized Kaposi sarcoma (KS), arising multicentrically in both palms and soles of a male patient who has had widespread psoriasis since 12 years of age. This 59-year-old man, of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_10220665" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">ABSTRACT: We report the case of drug-induced, acrolocalized Kaposi sarcoma (KS), arising multicentrically in both palms and soles of a male patient who has had widespread psoriasis since 12 years of age. This 59-year-old man, of Mediterranean origin, was HIV antibody-negative and had received oral prednisolone treatment over 5 months for chronic obstructive lung disease (initial dose: 75 mg/d). Eight months after discontinuing oral treatment the KS nodules regressed spontaneously and finally disappeared completely without additional treatment. Light and electron microscopic investigations confirmed the diagnosis of KS, whereas laboratory tests excluded HIV infection and suggested mild immune dysfunction. The existence of HLA loci predisposing to KS and to psoriasis (A1, DR5, DR7, DR11) was characteristic for the simultaneous occurrence of these two diseases. This case report demonstrates the complex interrelationships between genetic predisposition, drugs leading to immune suppression, and the evolution of an unusual neoplasm.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/10220665" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="6be62864aa2ba5d86ed69a19523ebedf" rel="nofollow" data-download="{"attachment_id":47479718,"asset_id":10220665,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47479718/download_file?st=MTczMzM2OTk2Myw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="24994381" href="https://lisboa.academia.edu/AugustoMayerdaSilva">Augusto Mayer-da-Silva</a><script data-card-contents-for-user="24994381" type="text/json">{"id":24994381,"first_name":"Augusto","last_name":"Mayer-da-Silva","domain_name":"lisboa","page_name":"AugustoMayerdaSilva","display_name":"Augusto Mayer-da-Silva","profile_url":"https://lisboa.academia.edu/AugustoMayerdaSilva?f_ri=168358","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_10220665 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="10220665"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 10220665, container: ".js-paper-rank-work_10220665", }); 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This 59-year-old man, of Mediterranean origin, was HIV antibody-negative and had received oral prednisolone treatment over 5 months for chronic obstructive lung disease (initial dose: 75 mg/d). Eight months after discontinuing oral treatment the KS nodules regressed spontaneously and finally disappeared completely without additional treatment. Light and electron microscopic investigations confirmed the diagnosis of KS, whereas laboratory tests excluded HIV infection and suggested mild immune dysfunction. The existence of HLA loci predisposing to KS and to psoriasis (A1, DR5, DR7, DR11) was characteristic for the simultaneous occurrence of these two diseases. 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