Maturing Pharma 4.0: How Digital Transformation Continues To Reshape Pharmaceuticals

<!DOCTYPE html> <html lang="en"> <head> <meta charset="UTF-8"> <title> Maturing Pharma 4.0: How Digital Transformation Continues To Reshape Pharmaceuticals </title> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link rel="canonical" href="https://www.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/" />  <script async src="https://www.googletagmanager.com/gtag/js?id=G-YK7FCK71TD"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-YK7FCK71TD'); </script> <meta name="description" content="" /> <meta name="keywords" content="" />  <meta name="twitter:card" content="summary_large_image"> <meta name="twitter:title" content="Maturing Pharma 4.0: How Digital Transformation Continues To Reshape Pharmaceuticals"> <meta name="twitter:description" content=""> <meta name="twitter:image" content="https://www.biopharmatrend.com/files/blog/social/blog/post-cover-109_fNqD9C5.jpg">  <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/" /> <meta property="og:title" content="Maturing Pharma 4.0: How Digital Transformation Continues To Reshape Pharmaceuticals" /> <meta property="og:description" content="" /> <meta property="article:published_time" content="2023-11-07T00:09:59+00:00"> <meta property="article:modified_time" content="2023-11-07T00:09:59+00:00"> <meta name="author" content="Tim Sandle"> <meta property="og:image" content="https://www.biopharmatrend.com/files/blog/social/blog/post-cover-109_fNqD9C5.jpg"> <script type="application/ld+json">{ "@context": "https://schema.org", "@type": "Article", "headline": "Maturing Pharma 4.0: How Digital Transformation Continues To Reshape Pharmaceuticals", "datePublished": "2023-11-07T00:09:59+00:00", "dateModified": "2023-11-07T00:09:59+00:00", "description": "The digital transformation of biopharmaceutical manufacturing has continued at a rapid pace as companies mine the rich sources of data available. The requirement for more people to maintain \u2018physical distance\u2019 during the coronavirus pandemic has helped to further fuel interest in digital solutions as companies sought to avoid delays and disruption to development, production and distribution. Innovations that enable data capture and review include predictive analytics, big data analytics, and building upon the digital plant. These forms of digital transformation offer mechanisms to revise its business model, to improve production processes, to design new drugs faster by using artificial intelligence (such as to screen compounds), and to increase responsiveness to customers. Furthermore, the volume of data processed by pharmaceutical firms shows no sign of slowing down. This means pharmaceutical companies must continue to act quickly in terms of building core internal digital capabilities and moving beyond their traditional IT functions to all areas of the business.", "image": "https://www.biopharmatrend.com/files/blog/social/blog/post-cover-109_fNqD9C5.jpg", "url": "https://www.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/", "mainEntityOfPage": { "@type": "WebPage", "@id": "https://www.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/" }, "publisher": { "@type": "Organization", "name": "BiopharmaTrend", "url": "https://www.biopharmatrend.com", "logo": { "@type": "ImageObject", "url": "https://www.biopharmatrend.com/static/img/bpt_logo.png" } }, "author": [ { "@type": "Person", "name": "Tim Sandle", "url": "https://www.biopharmatrend.com/contributor/41/" } ] }</script> <style type="text/css"> .ap-chart-load svg { width: 100%; } .post-meta 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</header> <footer class="post-meta"> <div class="tooltip"> <span class="glyphicon glyphicon-pencil"></span> by <a href="/contributor/41/">Tim Sandle</a> <a href="https://www.linkedin.com/in/timsandle/" rel="nofollow" target="_blank"> <img src="/static/img/linkedin_icon_50x50.71dcf83d1029.png" class="author-linkein-icon" /> </a> <span class="tooltip-trigger" onclick="this.parentElement.classList.toggle('tooltip-show')"> Contributor <i class="glyphicon glyphicon-info-sign"></i> </span>    <span style="white-space: nowrap;"> <span class="glyphicon glyphicon-folder-open"></span>   Biopharma insight / Biopharma Insights </span> <div class="tooltip-text"> <div class="tooltip-close" onclick="this.parentElement.parentElement.classList.toggle('tooltip-show');"></div> <p><b>Disclaimer</b>: All opinions expressed by Contributors are their own and do not represent those of their employers, or BiopharmaTrend.com. <br> Contributors are fully responsible for assuring they own any required copyright for any content they submit to BiopharmaTrend.com. This website and its owners shall not be liable for neither information and content submitted for publication by Contributors, nor its accuracy.</p> </div> </div> <div> <span class="glyphicon glyphicon-calendar" title="Published on"></span> <time datetime="2023-11-07">Nov. 7, 2023</time>    </em> </div> <div class="tags"> <b>Topics: </b> <a href="/topic/biopharma-manufacturing/">Manufacturing & Pharma 4.0</a>    </div> <div> <strong>Share: </strong>   <a target="_blank" rel="nofollow" href="https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Fwww.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/"> <img alt="Share in LinkedIn" src="/static/img/soc-in.7bc286fd757e.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://www.reddit.com/submit?url=https%3A%2F%2Fwww.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/"> <img alt="Share in Reddit" src="/static/img/soc-reddit.342e87a07115.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://twitter.com/intent/tweet?url=https%3A%2F%2Fwww.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/"> <img alt="Share in X" src="/static/img/soc-x.3c80e8291cba.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://news.ycombinator.com/submitlink?u=https%3A%2F%2Fwww.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/"> <img alt="Share in Hacker News" src="/static/img/soc-y.587f16a5f3f3.png" width="28" height="28"></a>  <a target="_blank" rel="nofollow" href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/&display=page"> <img alt="Share in Facebook" src="/static/img/soc-fb.3031a5a810f0.png" width="28" height="28" /></a>  <a target="_blank" rel="nofollow" href="mailto:?subject=Biopharmatrend.com&body=https%3A%2F%2Fwww.biopharmatrend.com/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/"> <img alt="Send by email" src="/static/img/soc-mail.41ce3608f438.png" width="28" height="28"></a> </div> </footer> <section> <p style="text-align: justify;">The digital transformation of biopharmaceutical manufacturing has continued at a rapid pace as companies mine the rich sources of data available. The requirement for more people to maintain ‘physical distance’ during the coronavirus pandemic has helped to further fuel interest in digital solutions as companies sought to avoid delays and disruption to development, production and distribution. Innovations that enable data capture and review include predictive analytics, big data analytics, and building upon the digital plant. These forms of digital transformation offer mechanisms to revise its business model, to improve production processes, to design new drugs faster by using artificial intelligence (such as to screen compounds), and to increase responsiveness to customers. Furthermore, the volume of data processed by pharmaceutical firms shows no sign of slowing down. This means pharmaceutical companies must continue to act quickly in terms of building core internal digital capabilities and moving beyond their traditional IT functions to all areas of the business.</p> <div style="overflow: hidden;"><h3 style="text-align: justify;">Regulatory interest</h3><p style="text-align: justify;">It is not only pharmaceutical companies who are driving digital technologies, there are expression of interest from regulators as well, as with undertaking more assessments of new products and clinical trials <a href="https://www2.deloitte.com/content/dam/Deloitte/uk/Documents/life-sciences-health-care/deloitte-uk-measuring-the-return-from-pharmaceutical-innovation-2021.pdf">through digital portals</a>. Perhaps the most important step is the U.S. FDA’s embracing of new methods to enhance the safety and security of the pharmaceutical distribution supply chain under the <a href="https://www.accessdata.fda.gov/scripts/fdatrack/view/track_project.cfm?program=cder&id=CDER-OC-Pilot-Project-Program">Drug Supply Chain Security Act (DSCSA)</a>. The continual application of the DSCSA initiative is intended to enhance the security of the pharmaceutical distribution supply chain and evaluate any pilot projects conducted prior to enactment of the law.</p><h3 style="text-align: justify;">Blockchain</h3><p style="text-align: justify;">One example of a new technology that was piloted and evaluated through the process was blockchain. Blockchain is software that provides a digital ledger system for records and log transactions, by grouping them into chronologically-ordered blocks. This makes it ideal for tracking supplies and ensuring that required storage conditions have been achieved and that goods have not been tampered with. Based on success stories relating to other sectors of the economy like financial services and energy suppliers, blockchain became seen as a suitable technology to meet the DSCSA requirement for an interoperable, electronic tracing of pharmaceutical products at the packaging level. This was demonstrated through a pilot program <a href="https://www.coindesk.com/markets/2020/05/04/ibm-merck-declare-fda-backed-drug-tracing-blockchain-a-success/">run jointly between IBM, KPMG, Merck and Walmart</a>, who worked closely with the FDA’s DSCSA pilot program. This is leading towards wider adoption in 2023 once the DSCA requirements for medicinal distribution come into force and with it the necessity to demonstrate full unit level traceability across the supply chain.</p><p style="text-align: justify;">To facilitate blockchain, competing solutions are available, each of which <a href="https://www.in-pharmatechnologist.com/Article/2019/03/11/TraceLink-submits-blockchain-solution-to-DSCSA-pilot-program">seeks to integrate directly into a healthcare company’s existing global infrastructure</a>. These integrations allow for the secure exchange of critical and confidential information with authorized partners in an open, interoperable format. the final 2023 DSCSA deadline requiring full unit level traceability across the supply chain.</p><p style="text-align: justify;">Outside of regulatory drivers, a number of pharmaceutical companies have been exploring other innovative technologies.</p></div> <div class="access-premium text-center"> <h3>Continue reading</h3> <p><big>This content available exclusively for BPT Mebmers</big></p> <div><a href="/membership/?success_page=/post/109-becoming-pharma-40-how-digital-transformation-is-reshaping-pharmaceuticals/&utm_source=website&utm_medium=post&utm_campaign=post_109" class="btn btn-bpt-white"> BPT Membership </a></div> <div><button type="button" onclick="document.getElementById('login-popup').classList.toggle('hidden')" class="btn btn-link" style="color:white; vertical-align: middle;"> Sign in </button></div> </div> <p> <b>Topics: </b> 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Maturing Pharma 4.0: How Digital Transformation Continues To Reshape Pharmaceuticals