Melt reports outcomes from trial of MELT-300 for cataract surgery

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href="https://www.clinicaltrialsarena.com/newsletters/"><span>Newsletters</span></a></li><ul></div> <div class="initials"><a href="https://www.clinicaltrialsarena.com">CT</a></div> </nav> <div class="menu-bg"></div> </header> <main class="article-page gdm-opinion-article"> <article> <div class="grid-x"> <div class="cell large-8"> <header class="article-header"> <div class="breadcrumbs-container"> <ul class="breadcrumbs"> <li class="breadcrumbs-item"> <a href="https://www.clinicaltrialsarena.com/news/" class="c-post-content__category">News</a> </li> </ul> <div class="date"> <span class="date-published"></span> </div> </div>  <div class="article-header__content"> <h1 class="article-header__title">Melt reports topline outcomes from trial of MELT-300 for cataract surgery</h1> <p class="article-header__excerpt">MELT-300 leverages Catalent’s Zydis technology for sublingual delivery.</p> <div class="article-meta"> <span class="date-published">November 21, 2024</span>  </div>  <div 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</header> <section class="article-content"> <div class="main-content"> <div class="article-image"> <figure class="article-image__container"> <picture> <source media="(min-width: 990px)" srcset="https://www.clinicaltrialsarena.com/wp-content/uploads/sites/22/2024/11/CTA-2-Melt-Shutterstock_376844431-770x433.jpg" /> <source media="(min-width: 430px)" srcset="https://www.clinicaltrialsarena.com/wp-content/uploads/sites/22/2024/11/CTA-2-Melt-Shutterstock_376844431-940x528.jpg" /> <img src="https://www.clinicaltrialsarena.com/wp-content/uploads/sites/22/2024/11/CTA-2-Melt-Shutterstock_376844431-430x241.jpg" alt="" /> </picture> <figcaption class="c-featured-image__description">The trial involved over 530 patients across 13 US clinical sites. Credit: Lucky Business/Shutterstock.</figcaption> </figure> </div> <p class="drop-cap">Melt Pharmaceuticals has reported encouraging topline results from its Phase III trial of MELT-300, a non-intravenous, non-opioid sedation tablet for cataract surgery.</p> <p>The pivotal study’s design, aligned with a Special Protocol Assessment agreement with the US Food and Drug Administration (FDA), supports the objectives necessary for a regulatory submission.</p><div class="in-article-premium-insights mobile-useragent-scalar"><div class="cell large-2 sidebar-scalar mobile-only"> <div class="gdm-widget gdm-recommended-reports gdm-pi-recommended-reports gdm-orange-banner recommended-whitepapers"><h3>Go deeper with GlobalData</h3><ul><li class="grid-x"><div class="cell small-2"><figure><a href=""><img decoding="async" src="https://pr-fr-json-b2b-gdm-figaro1.pantheonsite.io/pharmaceutical-technology/wp-content/themes/goodlife-wp-B2B/assets/img/report.png" alt="ReportsLogo" /></a></figure></div><div class="cell small-10 details"><div class="category"><a href="https://www.globaldata.com/store/report/" target="_blank">Reports</a></div><h4><a href=https://www.globaldata.com/store/report/lyt-200-in-myelodysplastic-syndrome-loa-and-ptsr-drug-analysis-350589?utm_source=Company News&utm_medium=22-221319&utm_campaign=recommended-reports-nonlgp target="_blank">LOA and PTSR Model - LYT-200 in Myelodysplastic Syndrome </a></h4></div> </li><li class="grid-x"><div class="cell small-2"><figure><a href=""><img decoding="async" src="https://pr-fr-json-b2b-gdm-figaro1.pantheonsite.io/pharmaceutical-technology/wp-content/themes/goodlife-wp-B2B/assets/img/report.png" alt="ReportsLogo" /></a></figure></div><div class="cell small-10 details"><div class="category"><a href="https://www.globaldata.com/store/report/" target="_blank">Reports</a></div><h4><a href=https://www.globaldata.com/store/report/midazolam-odt-in-sedation-loa-and-ptsr-drug-analysis-471914?utm_source=Company News&utm_medium=22-221319&utm_campaign=recommended-reports-nonlgp target="_blank">LOA and PTSR Model - Midazolam Odt in Sedation </a></h4></div> </li></ul> <div class="about-premium-insights"> <h5> <svg xmlns="http://www.w3.org/2000/svg" width="12" height="14" viewBox="0 0 12 14" fill="none"> <path d="M3.05664 1.29896C3.14886 1.29896 3.24174 1.28141 3.33128 1.24506C3.50101 1.1755 3.63131 1.0489 3.69947 0.887834C3.76696 0.726141 3.76429 0.550034 3.69012 0.390848C3.61661 0.231662 3.48096 0.109452 3.30923 0.0455268C3.13683 -0.0177716 2.94906 -0.0152648 2.77933 0.0543008C2.42985 0.197192 2.26881 0.580116 2.42117 0.908516C2.5341 1.15294 2.78869 1.29896 3.05664 1.29896ZM9.57846 13.0925C9.42611 12.7641 9.01782 12.6131 8.66768 12.756C8.31753 12.8989 8.15649 13.2818 8.30884 13.6102C8.42244 13.854 8.67703 14 8.94432 14C9.03653 14 9.12942 13.9825 9.21896 13.9461C9.56977 13.8045 9.73081 13.4215 9.57846 13.0925ZM8.69908 11.4298L6.85079 7.44266C6.7833 7.29727 6.60288 7.23021 6.44785 7.29351L5.9233 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8.90855 9.35528 10.2272C9.26373 10.3105 9.237 10.4384 9.28778 10.548L9.53235 11.0757C9.57178 11.1603 9.65197 11.2224 9.74819 11.2418C9.76957 11.2462 9.79162 11.2481 9.813 11.2481C9.88785 11.2481 9.96135 11.2224 10.0181 11.1741C11.9339 9.55407 12.53 6.97513 11.5016 4.75718C10.8641 3.38029 9.69072 2.31863 8.19792 1.76712Z" fill="#27274C"></path> </svg> Data Insights </h5> <p> The gold standard of business intelligence. </p> <p class="find-out-more"><a href="https://www.clinicaltrialsarena.com/buy-reports/?utm_source=LGP-Article&utm_content=Find_out_more&utm_campaign=LGP_Premium-Insight-Landing-Page" target="_blank"> Find out more <svg xmlns="http://www.w3.org/2000/svg" width="16" height="10" viewBox="0 0 16 10" fill="none"> <path d="M1 1.48846L8.02309 8.51156L15.0462 1.48846" stroke="#FF5D2B" stroke-linecap="round"></path> </svg> </a> </p> </div> </div></div><div class="sidebar-content"><div class="gd-widget related-company-profiles"><header><h3>Related Company Profiles</h3></header><div 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These overwhelmingly positive results support our belief that MELT-300, if approved by the FDA, would be a safe and effective non-IV, and non-opioid alternative to current IV-based cataract surgery sedation protocols, which generally involve the administration of opioids.</p> <p>“With the number of cataract surgeries performed each year in the US expected to exceed five million in the coming years, we believe offering patients and physicians the ability to achieve an adequate sedation level without the need to start an IV or administer opioids is a very attractive proposition.”</p><div id="slot-two"></div> <p>Catalent’s fast-dissolve formulation, Zydis, is claimed to be known for its rapid disintegration in the mouth, offering a convenient and palatable dosage form.</p> <p>This technology is particularly beneficial for patients with swallowing disorders, as well as paediatric and geriatric populations, requiring quick dosing and absorption for various treatments.</p> <p>In a Phase II 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}, function() { jQuery(this).animate({ height: '100px' }, 300); }); var hoverTime = 1000; var elements = [].slice.apply(document.querySelectorAll('.company-hover-data')); elements.forEach(function (el) { var timeout; el.addEventListener('mouseover', function (){ var match = jQuery(this).attr('data-url'); var hovertitle = jQuery(this).find('h3').html(); var curpostid = jQuery(this).attr('id'); var getpostid = curpostid.replace('company', ''); (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,'script','//www.google-analytics.com/analytics.js','ga'); ga('create', '', {'allowAnchor': true}); ga('set', 'title', hovertitle); ga('send', 'pageview', match); /* if(!jQuery(this).hasClass("verify")){ jQuery(this).addClass("verify"); timeout = window.setTimeout(function () { permutive.track('TabClick', { article: { url: match, title:hovertitle } }); }, hoverTime); } */ }); }); </script> <script> //jQuery('.preview-old').show(); </script> <script> function setCookie(cname, cvalue, exdays) { var d = new Date(); d.setTime(d.getTime() + (exdays*24*60*60*1000)); var expires = "expires="+ d.toUTCString(); document.cookie = cname + "=" + cvalue + ";" + expires + ";path=/"; } function getCookie(cname) { var name = cname + "="; var decodedCookie = decodeURIComponent(document.cookie); var ca = decodedCookie.split(';'); for(var i = 0; i <ca.length; i++) { var c = ca[i]; while (c.charAt(0) == ' ') { c = c.substring(1); } if (c.indexOf(name) == 0) { return c.substring(name.length, c.length); } } return ""; } permutive.once('Clearbit', function(clearbit){ if((clearbit.properties.company)!= null){ var company_id = clearbit.properties.company.id; } else{ var company_id = 'NA'; } permutive.segment(23691, function(result){ if (result && getCookie('globaldata_report') !== "shown") { jQuery('#globaldata_report').css('display','block'); setCookie('globaldata_report', 'shown', 7) permutive.track('ipTarget', { company:company_id, target_reason: "Globaldata", content: "Download a free 10 page preview of our Mergers & Acquisitions in TMT – Thematic Research 2019 Report", content_type: "targeted popup", content_url: "https://www.verdict.co.uk/download-a-free-10-page-preview-of-our-mergers-acquisitions-in-tmt-thematic-research-2019-report/" }) } }); permutive.segment(24097, function(result){ if (result && getCookie('corporate_meed') !== "shown") { jQuery('#corporate_meed').css('display','block'); setCookie('corporate_meed', 'shown', 7) permutive.track('ipTarget', { company:company_id, target_reason: "CorporateHealthAndWellness", content: "Why we believe workplace health and wellness is important", content_type: "targeted popup", content_url: "https://www.corporatehealthandwellness.meed.com/why-we-believe-workplace-health-and-wellness-is-important/" }) } }); permutive.segment(33716, function(result){ if (result && getCookie('oracle_meed') !== "shown") { jQuery('#oracle_meed').css('display','block'); setCookie('oracle_meed', 'shown', 7) permutive.track('ipTarget', { company:company_id, target_reason: "Orcale", content: "Q&A with Baraq Hadi: Vice President Middle East, Oracle Construction and Engineering", content_type: "targeted popup", content_url: "https://innovation.meed.com/qa-with-baraq-hadi-vice-president-middle-east-oracle-construction-and-engineering/" }) } }); permutive.segment(40190, function(result){ if (result && getCookie('Smartstream') !== "shown") { jQuery('#Smartstream').css('display','block'); setCookie('Smartstream', 'shown', 7) permutive.track('ipTarget', { company:company_id, target_reason: "Smartstream", content: "Fit for the future, whatever it looks like", content_type: "targeted popup", content_url: "https://www.verdict.co.uk/private-banker-international/future-banking-technology/fit-for-the-future-whatever-it-looks-like/" }) } }); permutive.segment(30918, function(result){ if (result && getCookie('target-novotech') !== "shown") { jQuery('#target-novotech').css('display','block'); setCookie('target-novotech', 'shown', 1) permutive.track('ipTarget', { company:company_id, target_reason: "Accelerating Clinical Trials", content: "Clinical Trial Continuity in Asia-Pacific during the COVID-19 pandemic", content_type: "targeted popup", content_url: "https://www.pharmaceutical-technology.com/sponsored/clinical-trial-continuity-in-asia-pacific-during-the-covid-19-pandemic/" }) } }); permutive.segment(21482, function(result){ if (result && getCookie('target-normet') !== "shown") { jQuery('#target-normet').css('display','block'); setCookie('target-normet', 'shown', 1) permutive.track('ipTarget', { company:company_id, target_reason: "Normet", content: "A sneak peek into Canada’s largest transit expansion", content_type: "targeted popup", content_url: "https://www.mining-technology.com/future-of-mining/a-sneak-peek-into-canadas-largest-transit-expansion" }) } }); permutive.segment(33196, function(result){ if (result && getCookie('target-sandvik') !== "shown") { jQuery('#target-sandvik').css('display','block'); setCookie('target-sandvik', 'shown', 1) permutive.track('ipTarget', { company:company_id, target_reason: "Sandvik", content: "Precision wire for vascular therapy: How EXERA® rises to the challenge", content_type: "targeted popup", content_url: "https://www.medicaldevice-network.com/precision-medical-wire/precision-wire-for-vascular-therapy-how-exera-rises-to-the-challenge" }) } }); }) </script> <script> jQuery( document ).ready(function() { function vmsnewTargetpopup(p1,p2,p3){ if( p1 != null && p2 !== null ) { jQuery.ajax({ type: "POST", url: "https://www.clinicaltrialsarena.com/wp-content/themes/goodlife-wp-B2B/target_modal.php", dataType: "html", data: { "segmentid": p1, "blogid": p2, }, success: function(data){ if( data.indexOf("false_partner") >= 0 ){ return false; //setCookie("target-"+p1+"_"+'22', 'shown', 1); }else{ jQuery(p3).html(data); //setCookie("target-"+p1+"_"+'22', 'shown', 1); } } }); } } var per_loop =1; permutive.segment(176648, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(176648); if(per_loop==1){ vmsnewTargetpopup(176648, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(176648, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(176648, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(199185, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(199185); if(per_loop==1){ vmsnewTargetpopup(199185, 30, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(199185, 30,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(199185, 30, '#resultnew_third'); } per_loop++; } } }); permutive.segment(47155, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(47155); if(per_loop==1){ vmsnewTargetpopup(47155, 26, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(47155, 26,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(47155, 26, '#resultnew_third'); } per_loop++; } } }); permutive.segment(122205, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(122205); if(per_loop==1){ vmsnewTargetpopup(122205, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(122205, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(122205, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(155983, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(155983); if(per_loop==1){ vmsnewTargetpopup(155983, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(155983, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(155983, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(83486, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(83486); if(per_loop==1){ vmsnewTargetpopup(83486, 17, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(83486, 17,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(83486, 17, '#resultnew_third'); } per_loop++; } } }); permutive.segment(81525, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(81525); if(per_loop==1){ vmsnewTargetpopup(81525, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(81525, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(81525, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(181571, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(181571); if(per_loop==1){ vmsnewTargetpopup(181571, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(181571, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(181571, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(104754, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(104754); if(per_loop==1){ vmsnewTargetpopup(104754, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(104754, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(104754, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(44460, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(44460); if(per_loop==1){ vmsnewTargetpopup(44460, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(44460, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(44460, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(98259, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(98259); if(per_loop==1){ vmsnewTargetpopup(98259, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(98259, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(98259, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(164191, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(164191); if(per_loop==1){ vmsnewTargetpopup(164191, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(164191, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(164191, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(99632, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(99632); if(per_loop==1){ vmsnewTargetpopup(99632, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(99632, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(99632, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(178673, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(178673); if(per_loop==1){ vmsnewTargetpopup(178673, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(178673, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(178673, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(162272, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(162272); if(per_loop==1){ vmsnewTargetpopup(162272, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(162272, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(162272, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(207295, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(207295); if(per_loop==1){ vmsnewTargetpopup(207295, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(207295, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(207295, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(39494, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(39494); if(per_loop==1){ vmsnewTargetpopup(39494, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(39494, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(39494, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(126060); if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(172149, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(172149); if(per_loop==1){ vmsnewTargetpopup(172149, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(172149, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(172149, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(124429, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(124429); if(per_loop==1){ vmsnewTargetpopup(124429, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(124429, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(124429, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(199290, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(199290); if(per_loop==1){ vmsnewTargetpopup(199290, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(199290, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(199290, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(131507, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(131507); if(per_loop==1){ vmsnewTargetpopup(131507, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(131507, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(131507, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(185678, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(185678); if(per_loop==1){ vmsnewTargetpopup(185678, 2, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(185678, 2,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(185678, 2, '#resultnew_third'); } per_loop++; } } }); permutive.segment(141355, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(141355); if(per_loop==1){ vmsnewTargetpopup(141355, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(141355, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(141355, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(103918, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(103918); if(per_loop==1){ vmsnewTargetpopup(103918, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(103918, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(103918, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(2491, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(2491); if(per_loop==1){ vmsnewTargetpopup(2491, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(2491, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(2491, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(187596, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(187596); if(per_loop==1){ vmsnewTargetpopup(187596, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(187596, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(187596, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(126060); if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(176357, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(176357); if(per_loop==1){ vmsnewTargetpopup(176357, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(176357, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(176357, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(187960, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(187960); if(per_loop==1){ vmsnewTargetpopup(187960, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(187960, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(187960, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(167527, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(167527); if(per_loop==1){ vmsnewTargetpopup(167527, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(167527, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(167527, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(126060); if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(190006, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(190006); if(per_loop==1){ vmsnewTargetpopup(190006, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(190006, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(190006, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(189369, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(189369); if(per_loop==1){ vmsnewTargetpopup(189369, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(189369, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(189369, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(199243, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(199243); if(per_loop==1){ vmsnewTargetpopup(199243, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(199243, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(199243, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(39494, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(39494); if(per_loop==1){ vmsnewTargetpopup(39494, 24, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(39494, 24,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(39494, 24, '#resultnew_third'); } per_loop++; } } }); permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(126060); if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(164848, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(164848); if(per_loop==1){ vmsnewTargetpopup(164848, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(164848, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(164848, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(33196, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(33196); if(per_loop==1){ vmsnewTargetpopup(33196, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(33196, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(33196, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(71444, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(71444); if(per_loop==1){ vmsnewTargetpopup(71444, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(71444, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(71444, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(126060); if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(61894, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(61894); if(per_loop==1){ vmsnewTargetpopup(61894, 24, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(61894, 24,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(61894, 24, '#resultnew_third'); } per_loop++; } } }); permutive.segment(106166, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(106166); if(per_loop==1){ vmsnewTargetpopup(106166, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(106166, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(106166, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(39494, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(39494); if(per_loop==1){ vmsnewTargetpopup(39494, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(39494, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(39494, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(88696, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(88696); if(per_loop==1){ vmsnewTargetpopup(88696, 26, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(88696, 26,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(88696, 26, '#resultnew_third'); } per_loop++; } } }); permutive.segment(106931, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(106931); if(per_loop==1){ vmsnewTargetpopup(106931, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(106931, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(106931, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(126060); if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(124429, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(124429); if(per_loop==1){ vmsnewTargetpopup(124429, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(124429, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(124429, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(195099, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(195099); if(per_loop==1){ vmsnewTargetpopup(195099, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(195099, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(195099, 22, '#resultnew_third'); } per_loop++; } } }); permutive.segment(193412, function(result){ if(per_loop<4){ if (result) { console.log(result); //console.log(193412); if(per_loop==1){ vmsnewTargetpopup(193412, 22, '#resultnew'); }if(per_loop==2){ vmsnewTargetpopup(193412, 22,'#resultnew_secondary'); }if(per_loop==3){ vmsnewTargetpopup(193412, 22, '#resultnew_third'); } per_loop++; } } }); }); </script>  <script> document.addEventListener("DOMContentLoaded", function(event) { let preFooter = document.createElement('div'); preFooter.className= 'pre-footer-subscribe'; preFooter.innerHTML = ` <a class="pre-footer-subscribe__all-newsletters" href="https://www.clinicaltrialsarena.com/all-newsletters"> <img src='https://www.clinicaltrialsarena.com/wp-content/themes/goodlife-wp-B2B/images/eye.svg' alt=''> <span class="text">View all newsletters</span> <span class="icon-chevron-right"></span> </a> <div class="pre-footer-subscribe__click" onclick="showPopUp('newsletter')"> <figure class="pre-footer-subscribe__figure"> <div class="lines"></div> </figure> <span class="text"> Receive our newsletter - data, insights and analysis delivered to you <span class="icon-chevron-right"></span></span> </div> ` var cfooterExist = document.getElementsByClassName('c-footer'); if (cfooterExist.length > 0) { document.querySelector('footer.c-footer').before(preFooter); } }) </script>  <script> jQuery('.c-related-companies-article__single').hover(function() { var hoverTime = 1000; var elements = [].slice.apply(document.querySelectorAll('.c-related-companies-article__single')); elements.forEach(function (el) { var timeout; el.addEventListener('mouseover', function (){ var match = jQuery(this).attr('data-url'); var hovertitle = jQuery(this).attr('data-target'); var curpostid = jQuery(this).attr('id'); var getpostid = curpostid.replace('company', ''); if(!jQuery(this).hasClass("verify")){ jQuery(this).addClass("verify"); timeout = window.setTimeout(function () { permutive.track('TabClick', { article: { url: match, title:hovertitle } }); }, hoverTime); } }); }); }); </script>  <script src="https://platform.twitter.com/oct.js" type="text/javascript"></script> <script type="text/javascript">if(typeof twttr !== undefined) twttr.conversion.trackPid('ocdmp', { tw_sale_amount: 0, tw_order_quantity: 0 });</script> <noscript> <img height="1" width="1" style="display:none;" alt="" src="https://analytics.twitter.com/i/adsct?txn_id=ocdmp&p_id=Twitter&tw_sale_amount=0&tw_order_quantity=0" /> <img height="1" width="1" style="display:none;" alt="" src="//t.co/i/adsct?txn_id=ocdmp&p_id=Twitter&tw_sale_amount=0&tw_order_quantity=0" /> </noscript>  <script> jQuery( document ).ready(function() { function vmsnewTargetpopup(p1,p2,p3){ jQuery.ajax({ type: "POST", url: "https://www.clinicaltrialsarena.com/wp-admin/admin-ajax.php", data: { action: 'In_Article_Ad_Slots', segmentid: p1, blogid: p2, }, success: function(data){ if(!jQuery.trim(data)){ }else{ jQuery(p3).html(data); } } }); } var per_loop =1; if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(162272, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(162272, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(162272, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(162272, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(47155, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(47155, 26, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(47155, 26, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(47155, 26, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(39494, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(39494, 24, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(39494, 24, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(39494, 24, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(176357, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(176357, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(176357, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(176357, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(2491, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(2491, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(2491, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(2491, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(189369, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(189369, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(189369, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(189369, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(185678, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(185678, 2, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(185678, 2, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(185678, 2, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(199185, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(199185, 30, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(199185, 30, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(199185, 30, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(178673, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(178673, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(178673, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(178673, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(131507, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(131507, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(131507, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(131507, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(104754, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(104754, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(104754, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(104754, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(124429, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(124429, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(124429, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(124429, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(195099, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(195099, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(195099, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(195099, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(103918, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(103918, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(103918, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(103918, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(126060, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(61894, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(61894, 24, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(61894, 24, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(61894, 24, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(71444, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(71444, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(71444, 22, '#slot-two'); }if(per_loop==3){ vmsnewTargetpopup(71444, 22, '#slot-three'); } per_loop++; } } }); } if(typeof(crbTracker.permutive.workspaceID) != "undefined" && crbTracker.permutive.workspaceID !== null && typeof(crbTracker.permutive.publicAPIKey) != "undefined" && crbTracker.permutive.publicAPIKey !== null) { permutive.segment(126060, function(result){ if(per_loop<4){ if (result) { if(per_loop==1){ vmsnewTargetpopup(126060, 22, '#slot-one'); }if(per_loop==2){ vmsnewTargetpopup(126060, 22, '#slot-two'); 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Melt reports outcomes from trial of MELT-300 for cataract surgery