Über Alnylam | Alnylam-de

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class="" href="https://capella.alnylam.com/our-science/capella-rnai-innovation"><span> Capella (Scientific Presentations) </span></a></li> </ul></div></div></li> </ul> </nav> <div class="second-mobile-menu"> <div class="container_inner"> <nav class="mobile_menu"> <ul> <li class="menu-item has_sub"> <p>Investoren</p> <a class="d-none hide" href="/">Investoren</a> <span class="mobile_arrow"></span> <ul class="sub_menu"> <li class="menu-item"><a class="" href="https://investors.alnylam.com/"><span> Investoren </span></a></li> </ul></li> <li class="menu-item has_sub"> <p>Medizinische Fachkreise</p> <a class="d-none hide" href="/">Medizinische Fachkreise</a> <span class="mobile_arrow"></span> <ul class="sub_menu"> <li class="menu-item"><a class="" href="/node/17"><span> Fachkreise </span></a></li> </ul></li> <li class="menu-item has_sub"> <p>Karriere bei Alnylam</p> <a class="d-none hide" href="/">Karriere bei Alnylam</a> <span class="mobile_arrow"></span> <ul class="sub_menu"> <li 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class="flow-icon"> <img class="img-fluid" src="/themes/custom/alnylam/img/social-icons/mobile-youtube.svg"> </a> <a target="_blank" href="https://www.facebook.com/AlnylamPharma/" class="flow-icon"> <img class="img-fluid" src="/themes/custom/alnylam/img/social-icons/facebook.svg"> </a> <a target="_blank" href="https://twitter.com/alnylam" class="flow-icon"> <img class="img-fluid" src="/themes/custom/alnylam/img/social-icons/mobile-twitter.png"> </a> <a target="_blank" href="https://www.linkedin.com/company/alnylam-pharmaceuticals/" class="flow-icon"> <img class="img-fluid" src="/themes/custom/alnylam/img/social-icons/mobile-likedin.png"> </a> <a target="_blank" href="https://www.instagram.com/alnylampharma/" class="flow-icon"> <img class="img-fluid" src="/themes/custom/alnylam/img/social-icons/mobile-instagram.svg"> </a> <a target="_blank" href="https://www.alnylam.com/signup-for-updates" class="flow-icon"> <img class="img-fluid" src="/themes/custom/alnylam/img/icon-social-email-mobile.svg"> </a> </div> </div> </div> </header> </div> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="container-fluid p-0"> <div class="row g-0"> <div class="order-1 order-lg-2 col-12">     <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div>     <div id="block-alnylam-content" class="block block-system block-system-main-block">     <article data-history-node-id="5" class="node node--type-page node--view-mode-full"> <div class="node__content">     <div class="field field--name-field-sections field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item">     <div class="paragraph paragraph--type--sim paragraph-id--8 paragraph--view-mode--default"> <div id="simple-banner-wrapper"> <div class="simple-banner" style="">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/About_Alnylam_header_v2.jpg" width="1280" height="384" alt="" loading="lazy" class="img-fluid" />   </div>  </div> </div> </div>  </div> <div class="field__item">     <div class="paragraph paragraph--type--banner-overlay-html-content paragraph-id--9 paragraph--view-mode--default"> <div class="about-alnylam-section banner-overlay-html-content-description--component " style="width:1130px; margin:auto;">     <div class="clearfix text-formatted field field--name-field-body field--type-text-with-summary field--label-hidden field__item"><p class="mobile-eyebrow"><span class="our-company">Unser Unternehmen</span></p><div class="about-alnylam text-center"><div class="row"><div class="col-sm-12"><h1 class="our-company">Über Alnylam</h1><h2>Unsere Forschung verändert die Art und Weise, wie Krankheiten medizinisch behandelt werden können.</h2><p class="font-20">Alnylam war Vorreiter bei der Umsetzung der Nobelpreis-gekrönten Entdeckung der RNAi (RNA-Interferenz) in eine innovative, völlig neue Klasse von Medikamenten. Alnylam wurde 2002 von einem Team herausragender Wissenschaftler gegründet. Die Vision von Alnylam ist es, das Potenzial von RNAi-Therapeutika für Menschen nutzbar zu machen, für deren Krankheiten es nur begrenzte oder unzureichende Behandlungsmöglichkeiten gibt. Dank unserer Pionierarbeit sind die weltweit ersten und bisher einzigen zugelassenen RNAi-Therapeutika entwickelt worden. Zwischen 2018 und 2022 wurden bereits vier Medikamente aus unserer Entwicklung zugelassen. Wir verfügen über eine umfangreiche Produktpipeline innovativer RNAi-basierter Medikamente, die vier Therapiebereiche abdecken: genetische Erkrankungen, kardio-metabolische Erkrankungen, Infektionskrankheiten sowie Erkrankungen des zentralen Nervensystems (ZNS) und des Auges.</p></div></div></div></div>  </div> </div>  </div> <div class="field__item">     <div class="paragraph paragraph--type--body paragraph-id--139 paragraph--view-mode--default"> <div class="light-blue ptb-64 mb-64"> <div class="description--component" style="width:1130px; margin:auto; ">     <div class="clearfix text-formatted field field--name-field-body field--type-text-with-summary field--label-hidden field__item"><div class="inner-bg-light-blue text-center" style="margin:auto;width:1130px;"><h2>Was verbirgt sich hinter dem Namen „Alnylam“?</h2><p class="text-start">AL-NY-LAM. Unser Name ist nicht einfach auszusprechen, aber einmal gelernt, vergisst man ihn nicht mehr. Alnylam ist abgeleitet von “Alnilam” dem hellen Zentralstern im Gürtel des Sternbildes Orion. Er wird seit Jahrtausenden von Seefahrern zur Orientierung genutzt. Dieser Stern steht symbolisch für unsere Leidenschaft für Entdeckungen.</p></div></div>  </div> </div> </div>  </div> <div class="field__item">     <div class="paragraph paragraph--type--body paragraph-id--140 paragraph--view-mode--default"> <div class="mb-32"> <div class="description--component" style="width:1130px; margin:auto; ">     <div class="clearfix text-formatted field field--name-field-body field--type-text-with-summary field--label-hidden field__item"><div class="about-alnylam text-center"><div class="row"><div class="col-sm-12"><h2>RNAi-Therapeutika – eine innovative, neue Klasse von Medikamenten</h2><p class="text-start">RNAi-basierte Medikamente wirken, indem sie die Produktion (“Expression”) derjenigen Gene, die bestimmte Krankheiten verursachen, “zum Schweigen bringen”, also reversibel deaktivieren. Auf diese Weise arbeiten RNAi-Therapeutika sozusagen “gegen den Strom” der meisten Arzneimittelklassen, wie etwa kleine chemische Moleküle oder monoklonale Antikörper: Sie setzen bei der eigentlichen, genetischen Ursache einer Krankheit an, anstatt nur auf die Krankheitssymptome abzuzielen. Für mehr Informationen zu unserem wissenschaftlichen Verfahren, <a href="/unsere-wissenschaft">klicken Sie bitte hier</a>.</p><p class="text-start mt-24">RNAi ist die zentrale Entdeckung, auf der die von Alnylam entwickelten Therapien beruhen. Sie gilt als großer wissenschaftlicher Durchbruch. Aber wie funktioniert das genau?</p></div></div></div></div>  </div> </div> </div>  </div> <div class="field__item">     <div class="paragraph paragraph--type--video-popup paragraph-id--10 paragraph--view-mode--default"> <div class="video-popup-content " style="width:850px; margin:auto;"> <a data-colorbox-inline=".video-box-10" style="width: 571px; height:326px;"> <div class="three-column-image-box">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/For-patients_Understanding-RNAi.jpg" width="850" height="480" alt="" loading="lazy" class="img-fluid" />   </div>  <div class="three-column-video-play-button popup-video"></div> <div class="popup-iframe"> <div class="video-wrapper"> <span class="close-btn"> </span>     <div class="field field--name-field-embed-video field--type-video-embed-field field--label-hidden field__item">    <div class="video-embed-field-provider-youtube video-embed-field-responsive-video">     <iframe width="854" height="480" frameborder="0" allowfullscreen="allowfullscreen" src="https://www.youtube.com/embed/VnlutE2X7C4?autoplay=1&start=0&rel=0"></iframe>  </div>  </div>  </div> </div> </div> </a> <div class="video-popup-desc">     <div class="clearfix text-formatted field field--name-field-video-desc field--type-text-long field--label-hidden field__item"><div><p>Erfahren Sie mehr über die Wirkungsweise von <strong>RNAi-basierten Medikamenten</strong></p></div></div>  </div> </div> </div>  </div> <div class="field__item">     <div class="paragraph paragraph--type--_-column-card paragraph-id--14 paragraph--view-mode--default"> <div class="three-column-card-content" style="background-color:#f8f8f8;"> <div style="width:1170px; margin:auto; "> <div class="three-column-card-title">     <div class="field field--name-field-heading-1 field--type-string field--label-hidden field__item">Vision, Mission und Werte</div>  </div> <div class="three-column-card-box">     <div class="field field--name-field-3-column-card field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item">     <div class="paragraph paragraph--type--image-title-description paragraph-id--11 paragraph--view-mode--default"> <div class="image-title-desc-box"> <div class="image-box">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/Aln_Icons_Vision.png" width="146" height="146" alt="" loading="lazy" class="img-fluid" />   </div>  </div> <h3 class="title-text">     <div class="field field--name-field-title field--type-string field--label-hidden field__item">Unsere Vision</div>  </h3> <div class="desc-box">     <div class="clearfix text-formatted field field--name-field-body field--type-text-with-summary field--label-hidden field__item"><p>Unsere Vision ist es, eine Revolution in der Biologie zum Wohle der menschlichen Gesundheit zu nutzen®.</p></div>  </div> </div> </div>  </div> <div class="field__item">     <div class="paragraph paragraph--type--image-title-description paragraph-id--12 paragraph--view-mode--default"> <div class="image-title-desc-box"> <div class="image-box">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/Aln_Icons_Mission.png" width="146" height="146" alt="" loading="lazy" class="img-fluid" />   </div>  </div> <h3 class="title-text">     <div class="field field--name-field-title field--type-string field--label-hidden field__item">Unsere Mission</div>  </h3> <div class="desc-box">     <div class="clearfix text-formatted field field--name-field-body field--type-text-with-summary field--label-hidden field__item"><p>Wir wollen ein erstklassiges, globales, unabhängiges biopharmazeutisches Unternehmen auf Basis der RNAi-Technologie aufbauen.</p></div>  </div> </div> </div>  </div> <div class="field__item">     <div class="paragraph paragraph--type--image-title-description paragraph-id--13 paragraph--view-mode--default"> <div class="image-title-desc-box"> <div class="image-box">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/Aln_Icons_Values.png" width="146" height="146" alt="" loading="lazy" class="img-fluid" />   </div>  </div> <h3 class="title-text">     <div class="field field--name-field-title field--type-string field--label-hidden field__item">Unsere Grundwerte</div>  </h3> <div class="desc-box">     <div class="clearfix text-formatted field field--name-field-body field--type-text-with-summary field--label-hidden field__item"><p>Engagement für die Menschen, leidenschaftlich innovativ, zielgerichtete Dringlichkeit, eine offene Unternehmenskultur und die Leidenschaft für Spitzenleistungen</p></div>  </div> </div> </div>  </div> </div>  </div> </div> </div> </div>  </div> <div class="field__item">     <section class="whole-video-with-content-area" style="width:1170px; margin:auto; padding:64px 0px;"> <div class="video-with-conten-title">     <div class="field field--name-field-heading-1 field--type-string field--label-hidden field__item">Die Alnylam-Story—Von der Entdeckung zum Patienten</div>  </div> <div class="video-with-content-box">     <div class="field field--name-field-title-description-video-vi field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item">     <div> <div class="whole-title-description-video-video-th-area video-right" style="overflow:hidden;"> <div class="row"> <div class="col-sm-6"> <a data-colorbox-inline=".video-box-15" style="width: 650px; height:400px;"> <div class="three-column-image-box">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/RNAi_Boom_image_about_alnylam-1_2.png" width="535" height="301" alt="" loading="lazy" class="img-fluid" />   </div>  <div class="three-column-video-play-button popup-video"> <img class="normal-video" src="/themes/custom/alnylam/images/play-button-56-px.svg"> <img class="active-video" src="/themes/custom/alnylam/images/play-button-active-56-px.svg"> </div> <div class="popup-iframe"> <div class="video-wrapper"> <span class="close-btn"> </span>     <div class="field field--name-field-embed-video field--type-video-embed-field field--label-hidden field__item">    <div class="video-embed-field-provider-youtube video-embed-field-responsive-video">     <iframe width="854" height="480" frameborder="0" allowfullscreen="allowfullscreen" src="https://www.youtube.com/embed/U8wGObcV5hg?autoplay=1&start=0&rel=0"></iframe>  </div>  </div>  </div> </div> </div> </a> <div class="video-desc">     <div class="clearfix text-formatted field field--name-field-video-desc field--type-text-long field--label-hidden field__item"><p>Von der Entdeckung zum Patienten: <strong>Der Heureka-Moment</strong></p></div>  </div> </div> <div class="col-sm-6 text-content"> <div class="title-text">     <div class="field field--name-field-title field--type-string field--label-hidden field__item">Der Heureka-Moment</div>  </div> <div class="description">     <div class="clearfix text-formatted field field--name-field-description-text-area field--type-text-long field--label-hidden field__item"><p>In der wegweisenden Forschung gibt es oft einen besonderen Moment – einen Moment, in dem klar wird, dass eine Entdeckung das Potenzial hat, Wissenschaft und Medizin, so wie wir sie kennen, grundlegend zu verändern. Dies ist der Heureka-Moment, auf dem Alnylam aufgebaut wurde.</p></div>  </div> </div> </div> </div> </div>  </div> <div class="field__item">     <div> <div class="whole-title-description-video-video-th-area video-left" style="overflow:hidden;"> <div class="row"> <div class="col-sm-6"> <a data-colorbox-inline=".video-box-16" style="width: 650px; height:400px;"> <div class="three-column-image-box">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/RNAi_Boom_image_about_alnylam-1_2%20%281%29.png" width="436" height="245" alt="" loading="lazy" class="img-fluid" />   </div>  <div class="three-column-video-play-button popup-video"> <img class="normal-video" src="/themes/custom/alnylam/images/play-button-56-px.svg"> <img class="active-video" src="/themes/custom/alnylam/images/play-button-active-56-px.svg"> </div> <div class="popup-iframe"> <div class="video-wrapper"> <span class="close-btn"> </span>     <div class="field field--name-field-embed-video field--type-video-embed-field field--label-hidden field__item">    <div class="video-embed-field-provider-youtube video-embed-field-responsive-video">     <iframe width="854" height="480" frameborder="0" allowfullscreen="allowfullscreen" src="https://www.youtube.com/embed/GwP_gSe45SM?autoplay=1&start=0&rel=0"></iframe>  </div>  </div>  </div> </div> </div> </a> <div class="video-desc">     <div class="clearfix text-formatted field field--name-field-video-desc field--type-text-long field--label-hidden field__item"><p>Von der Entdeckung zum Patienten: Die Odyssee der Wissenschaft—<strong>der RNAi-Boom</strong></p></div>  </div> </div> <div class="col-sm-6 text-content"> <div class="title-text">     <div class="field field--name-field-title field--type-string field--label-hidden field__item">DER RNAi-BOOM</div>  </div> <div class="description">     <div class="clearfix text-formatted field field--name-field-description-text-area field--type-text-long field--label-hidden field__item"><p>Es gab eine Zeit, in der das Interesse an RNAi boomte. Jeder wollte mitmachen. Die Begeisterung für diesen vielversprechenden neuen Ansatz zur Behandlung von Krankheiten zog viele Pharmaunternehmen in ihren Bann, führte zur Investition von Millionen von Dollar und entzündete den Ehrgeiz, als Erster das Potential dieser neuen Entdeckung zu erschließen.</p></div>  </div> </div> </div> </div> </div>  </div> <div class="field__item">     <div> <div class="whole-title-description-video-video-th-area video-right" style="overflow:hidden;"> <div class="row"> <div class="col-sm-6"> <a data-colorbox-inline=".video-box-17" style="width: 650px; height:400px;"> <div class="three-column-image-box">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/RNAi_Boom_image_about_alnylam.jpg" width="436" height="245" alt="" loading="lazy" class="img-fluid" />   </div>  <div class="three-column-video-play-button popup-video"> <img class="normal-video" src="/themes/custom/alnylam/images/play-button-56-px.svg"> <img class="active-video" src="/themes/custom/alnylam/images/play-button-active-56-px.svg"> </div> <div class="popup-iframe"> <div class="video-wrapper"> <span class="close-btn"> </span>     <div class="field field--name-field-embed-video field--type-video-embed-field field--label-hidden field__item">    <div class="video-embed-field-provider-youtube video-embed-field-responsive-video">     <iframe width="854" height="480" frameborder="0" allowfullscreen="allowfullscreen" src="https://www.youtube.com/embed/HptpAZ5QhgY?autoplay=1&start=0&rel=0"></iframe>  </div>  </div>  </div> </div> </div> </a> <div class="video-desc">     <div class="clearfix text-formatted field field--name-field-video-desc field--type-text-long field--label-hidden field__item"><p>Von der Entdeckung zum Patienten: Die wissenschaftliche Odyssee—<strong>Die dunklen Zeiten</strong></p></div>  </div> </div> <div class="col-sm-6 text-content"> <div class="title-text">     <div class="field field--name-field-title field--type-string field--label-hidden field__item">Die dunklen Zeiten</div>  </div> <div class="description">     <div class="clearfix text-formatted field field--name-field-description-text-area field--type-text-long field--label-hidden field__item"><p>Alnylam stand in seiner frühen Geschichte vor vielen Herausforderungen. Die Auflösung wichtiger Partnerschaften führte zu Unsicherheiten im Unternehmen und außerhalb Alnylams zu einem Vertrauensverlust in die Technologie. Innerhalb von Alnylam blieben aber der unerschütterliche Glaube, der starke Wille, die Begeisterung und der Antrieb, RNAi-Therapeutika Wirklichkeit werden zu lassen, bestehen.</p></div>  </div> </div> </div> </div> </div>  </div> <div class="field__item">     <div> <div class="whole-title-description-video-video-th-area video-left" style="overflow:hidden;"> <div class="row"> <div class="col-sm-6"> <a data-colorbox-inline=".video-box-18" style="width: 650px; height:400px;"> <div class="three-column-image-box">     <div class="field field--name-field-upload-image field--type-image field--label-hidden field__item">       <img src="/sites/default/files/2023-08/the_slope_of_enlightenment.jpg" width="436" height="245" alt="" loading="lazy" class="img-fluid" />   </div>  <div class="three-column-video-play-button popup-video"> <img class="normal-video" src="/themes/custom/alnylam/images/play-button-56-px.svg"> <img class="active-video" src="/themes/custom/alnylam/images/play-button-active-56-px.svg"> </div> <div class="popup-iframe"> <div class="video-wrapper"> <span class="close-btn"> </span>     <div class="field field--name-field-embed-video field--type-video-embed-field field--label-hidden field__item">    <div class="video-embed-field-provider-youtube video-embed-field-responsive-video">     <iframe width="854" height="480" frameborder="0" allowfullscreen="allowfullscreen" src="https://www.youtube.com/embed/85WpO4hfN2o?autoplay=1&start=0&rel=0"></iframe>  </div>  </div>  </div> </div> </div> </a> <div class="video-desc">     <div class="clearfix text-formatted field field--name-field-video-desc field--type-text-long field--label-hidden field__item"><p>Von der Entdeckung zum Patienten: Die wissenschaftliche Odyssee—<strong>Der Weg zur Erleuchtung</strong></p></div>  </div> </div> <div class="col-sm-6 text-content"> <div class="title-text">     <div class="field field--name-field-title field--type-string field--label-hidden field__item">Der Weg zur Erleuchtung</div>  </div> <div class="description">     <div class="clearfix text-formatted field field--name-field-description-text-area field--type-text-long field--label-hidden field__item"><p>Nach der Bewältigung scheinbar unüberwindbarer Herausforderungen, hat Alnylam einen robusten Forschungs- und Entwicklungs- „Motor“ sowie eine umfangreiche Produktpipeline von RNAi-Therapeutika aufgebaut. Sie haben das Potenzial, ein breites Spektrum an Krankheiten zu behandeln. 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