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skin","url":"https://www.academia.edu/Documents/in/Human_skin-1?f_ri=162553"},{"id":4384029,"name":"NG-nitroarginine methyl ester","url":"https://www.academia.edu/Documents/in/NG_nitroarginine_methyl_ester?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125957529" data-work_id="125957529" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125957529/A_Case_of_Epidermodysplasia_Verruciformis_A_First_Case_Report_from_Yemen">A Case of Epidermodysplasia Verruciformis: A First Case Report from Yemen</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Epidermodysplasia verruciformis (EV) is a rare genodermatosis associated with decreased immunity against certain types of human papillomaviruses that are associated with a high risk for cutaneous dysplasia and skin cancer. Herein, we... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125957529" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Epidermodysplasia verruciformis (EV) is a rare genodermatosis<br />associated with decreased immunity against certain types of human papillomaviruses that are associated with a high risk for cutaneous dysplasia and skin cancer. Herein, we present the case of a<br />35-year-old man with seborrheic keratosis-like lesions on his face,<br />plane wart-like lesions on both hands, erythematous macules bilaterally on his neck, and pityriasis versicolor-like lesions on both<br />arms. The onset occurred in the second decade of his life, at which<br />time he reported similar lesions affecting his father and brother.<br />Histopathological findings confirmed the diagnosis of EV. Interestingly, this is the first such case to be reported in Yemen.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125957529" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ba9f4a2ba79e73d047e3e6f0b188fdac" rel="nofollow" data-download="{&quot;attachment_id&quot;:119909491,&quot;asset_id&quot;:125957529,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119909491/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="270458791" href="https://independent.academia.edu/unitedprime">united prime</a><script data-card-contents-for-user="270458791" type="text/json">{"id":270458791,"first_name":"united","last_name":"prime","domain_name":"independent","page_name":"unitedprime","display_name":"united prime","profile_url":"https://independent.academia.edu/unitedprime?f_ri=162553","photo":"https://0.academia-photos.com/270458791/120854747/110183129/s65_united.prime.png"}</script></span></span></li><li class="js-paper-rank-work_125957529 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125957529"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125957529, container: ".js-paper-rank-work_125957529", }); 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Herein, we present the case of a\n35-year-old man with seborrheic keratosis-like lesions on his face,\nplane wart-like lesions on both hands, erythematous macules bilaterally on his neck, and pityriasis versicolor-like lesions on both\narms. The onset occurred in the second decade of his life, at which\ntime he reported similar lesions affecting his father and brother.\nHistopathological findings confirmed the diagnosis of EV. Interestingly, this is the first such case to be reported in Yemen.","downloadable_attachments":[{"id":119909491,"asset_id":125957529,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":270458791,"first_name":"united","last_name":"prime","domain_name":"independent","page_name":"unitedprime","display_name":"united prime","profile_url":"https://independent.academia.edu/unitedprime?f_ri=162553","photo":"https://0.academia-photos.com/270458791/120854747/110183129/s65_united.prime.png"}],"research_interests":[{"id":63886,"name":"Case Report","url":"https://www.academia.edu/Documents/in/Case_Report?f_ri=162553","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125956854" data-work_id="125956854" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a 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u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="125954374"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">20</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="159" href="https://www.academia.edu/Documents/in/Microbiology">Microbiology</a>,&nbsp;<script data-card-contents-for-ri="159" type="text/json">{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="164" href="https://www.academia.edu/Documents/in/Parasitology">Parasitology</a>,&nbsp;<script data-card-contents-for-ri="164" type="text/json">{"id":164,"name":"Parasitology","url":"https://www.academia.edu/Documents/in/Parasitology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="6947" href="https://www.academia.edu/Documents/in/Medical_Microbiology">Medical Microbiology</a>,&nbsp;<script data-card-contents-for-ri="6947" type="text/json">{"id":6947,"name":"Medical Microbiology","url":"https://www.academia.edu/Documents/in/Medical_Microbiology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a><script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125954374]'), work: {"id":125954374,"title":"Behavioural strategies used by the hookworms Necator americanus and Ancylostoma duodenale to find, recognize and invade the human 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Duodenale","url":"https://www.academia.edu/Documents/in/Ancylostoma_Duodenale?f_ri=162553"},{"id":1111007,"name":"Necator Americanus","url":"https://www.academia.edu/Documents/in/Necator_Americanus?f_ri=162553"},{"id":1251210,"name":"Blood Vessel","url":"https://www.academia.edu/Documents/in/Blood_Vessel?f_ri=162553"},{"id":3826324,"name":"Human skin","url":"https://www.academia.edu/Documents/in/Human_skin-1?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125954362" data-work_id="125954362" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125954362/Behavioural_strategies_used_by_the_hookworms_Necator_americanus_and_Ancylostoma_duodenale_to_find_recognize_and_invade_the_human_host">Behavioural strategies used by the hookworms Necator americanus and Ancylostoma duodenale to find, recognize and invade the human host</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125954362" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="80cc30ad061fdfe84ec154d43ae76d04" rel="nofollow" data-download="{&quot;attachment_id&quot;:119907045,&quot;asset_id&quot;:125954362,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119907045/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="306973090" href="https://independent.academia.edu/DennisKallert">Dennis Kallert</a><script data-card-contents-for-user="306973090" type="text/json">{"id":306973090,"first_name":"Dennis","last_name":"Kallert","domain_name":"independent","page_name":"DennisKallert","display_name":"Dennis Kallert","profile_url":"https://independent.academia.edu/DennisKallert?f_ri=162553","photo":"https://0.academia-photos.com/306973090/151502163/141090972/s65_dennis.kallert.jpeg"}</script></span></span></li><li class="js-paper-rank-work_125954362 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125954362"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125954362, container: ".js-paper-rank-work_125954362", }); });</script></li><li class="js-percentile-work_125954362 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 125954362; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var 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u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="125954362"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">20</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="159" href="https://www.academia.edu/Documents/in/Microbiology">Microbiology</a>,&nbsp;<script data-card-contents-for-ri="159" type="text/json">{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="164" href="https://www.academia.edu/Documents/in/Parasitology">Parasitology</a>,&nbsp;<script data-card-contents-for-ri="164" type="text/json">{"id":164,"name":"Parasitology","url":"https://www.academia.edu/Documents/in/Parasitology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="6947" href="https://www.academia.edu/Documents/in/Medical_Microbiology">Medical Microbiology</a>,&nbsp;<script data-card-contents-for-ri="6947" type="text/json">{"id":6947,"name":"Medical Microbiology","url":"https://www.academia.edu/Documents/in/Medical_Microbiology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a><script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125954362]'), work: {"id":125954362,"title":"Behavioural strategies used by the hookworms Necator americanus and Ancylostoma duodenale to find, recognize and invade the human 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Saving","url":"https://www.academia.edu/Documents/in/Energy_Saving?f_ri=162553"},{"id":128057,"name":"Light","url":"https://www.academia.edu/Documents/in/Light?f_ri=162553"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin?f_ri=162553"},{"id":442493,"name":"Larva","url":"https://www.academia.edu/Documents/in/Larva?f_ri=162553"},{"id":469102,"name":"Feces","url":"https://www.academia.edu/Documents/in/Feces?f_ri=162553"},{"id":486713,"name":"Fatty Acid","url":"https://www.academia.edu/Documents/in/Fatty_Acid?f_ri=162553"},{"id":585573,"name":"Amino Acid Profile","url":"https://www.academia.edu/Documents/in/Amino_Acid_Profile?f_ri=162553"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences?f_ri=162553"},{"id":784076,"name":"Species Specificity","url":"https://www.academia.edu/Documents/in/Species_Specificity?f_ri=162553"},{"id":1111006,"name":"Ancylostoma Duodenale","url":"https://www.academia.edu/Documents/in/Ancylostoma_Duodenale?f_ri=162553"},{"id":1111007,"name":"Necator Americanus","url":"https://www.academia.edu/Documents/in/Necator_Americanus?f_ri=162553"},{"id":1251210,"name":"Blood Vessel","url":"https://www.academia.edu/Documents/in/Blood_Vessel?f_ri=162553"},{"id":3826324,"name":"Human skin","url":"https://www.academia.edu/Documents/in/Human_skin-1?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125952696" data-work_id="125952696" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125952696/Acute_complex_traumas_of_the_lower_limbs_a_modern_reconstructive_approach_with_negative_pressure_therapy">Acute complex traumas of the lower limbs: a modern reconstructive approach with negative pressure therapy</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">ABSTRACTAcute traumas of the lower limbs cause complex functional damage for the association of skin loss with exposed tendons, bones, and/or vessels, requiring a multidisciplinary approach. Once bone fixation and vascular repair have... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125952696" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">ABSTRACTAcute traumas of the lower limbs cause complex functional damage for the association of skin loss with exposed tendons, bones, and/or vessels, requiring a multidisciplinary approach. Once bone fixation and vascular repair have been carried out, the surgical treatment for skin damage is usually based on early coverage with conventional or microsurgical flaps. Negative pressure therapy can play a primary role in the management of the elderly or intensive care patients, where wounds are secondary to life‐threatening problems. A total of 35 patients with 37 acute traumatic wounds of the lower limbs were treated with vacuum‐assisted closure (VAC®) therapy for an average of 22 days (range 3–46 days). The sponge was applied the day after bone fixation, vascular repair, and surgical debridement of nonviable tissues, so as to obtain a better control of bleeding. After VAC® treatment, all patients quickly developed healthy granulation tissue and a significant reduction in both extent ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125952696" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0aa561b2c617241b11d1b10d76f592be" rel="nofollow" data-download="{&quot;attachment_id&quot;:119905844,&quot;asset_id&quot;:125952696,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119905844/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="279402128" href="https://independent.academia.edu/MaurizioStella2">Maurizio Stella</a><script data-card-contents-for-user="279402128" type="text/json">{"id":279402128,"first_name":"Maurizio","last_name":"Stella","domain_name":"independent","page_name":"MaurizioStella2","display_name":"Maurizio Stella","profile_url":"https://independent.academia.edu/MaurizioStella2?f_ri=162553","photo":"https://0.academia-photos.com/279402128/127956851/117345410/s65_maurizio.stella.jpeg"}</script></span></span></li><li class="js-paper-rank-work_125952696 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125952696"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125952696, container: ".js-paper-rank-work_125952696", }); 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Once bone fixation and vascular repair have been carried out, the surgical treatment for skin damage is usually based on early coverage with conventional or microsurgical flaps. Negative pressure therapy can play a primary role in the management of the elderly or intensive care patients, where wounds are secondary to life‐threatening problems. A total of 35 patients with 37 acute traumatic wounds of the lower limbs were treated with vacuum‐assisted closure (VAC®) therapy for an average of 22 days (range 3–46 days). The sponge was applied the day after bone fixation, vascular repair, and surgical debridement of nonviable tissues, so as to obtain a better control of bleeding. After VAC® treatment, all patients quickly developed healthy granulation tissue and a significant reduction in both extent ...","downloadable_attachments":[{"id":119905844,"asset_id":125952696,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":279402128,"first_name":"Maurizio","last_name":"Stella","domain_name":"independent","page_name":"MaurizioStella2","display_name":"Maurizio Stella","profile_url":"https://independent.academia.edu/MaurizioStella2?f_ri=162553","photo":"https://0.academia-photos.com/279402128/127956851/117345410/s65_maurizio.stella.jpeg"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=162553","nofollow":false},{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing?f_ri=162553","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553","nofollow":false},{"id":160877,"name":"Vacuum","url":"https://www.academia.edu/Documents/in/Vacuum?f_ri=162553","nofollow":false},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin?f_ri=162553"},{"id":243489,"name":"Leg Ulcer","url":"https://www.academia.edu/Documents/in/Leg_Ulcer?f_ri=162553"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=162553"},{"id":372622,"name":"Granulation Tissue","url":"https://www.academia.edu/Documents/in/Granulation_Tissue?f_ri=162553"},{"id":448603,"name":"Necrosis","url":"https://www.academia.edu/Documents/in/Necrosis?f_ri=162553"},{"id":561006,"name":"Soft Tissue Injuries","url":"https://www.academia.edu/Documents/in/Soft_Tissue_Injuries?f_ri=162553"},{"id":561304,"name":"Lower limb","url":"https://www.academia.edu/Documents/in/Lower_limb?f_ri=162553"},{"id":687277,"name":"Pressure Ulcer","url":"https://www.academia.edu/Documents/in/Pressure_Ulcer?f_ri=162553"},{"id":810564,"name":"Negative Pressure Wound Therapy","url":"https://www.academia.edu/Documents/in/Negative_Pressure_Wound_Therapy?f_ri=162553"},{"id":1404065,"name":"Bandages","url":"https://www.academia.edu/Documents/in/Bandages?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125948164" data-work_id="125948164" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125948164/The_Pex1_G844D_mouse_A_model_for_mild_human_Zellweger_spectrum_disorder">The Pex1-G844D mouse: A model for mild human Zellweger spectrum disorder</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125948164" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fc4b2ae628a6ae1327fae181aa539359" rel="nofollow" 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{"id":125948164,"title":"The Pex1-G844D mouse: A model for mild human Zellweger spectrum disorder","created_at":"2024-11-29T17:29:42.652-08:00","url":"https://www.academia.edu/125948164/The_Pex1_G844D_mouse_A_model_for_mild_human_Zellweger_spectrum_disorder?f_ri=162553","dom_id":"work_125948164","summary":null,"downloadable_attachments":[{"id":119902012,"asset_id":125948164,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33311356,"first_name":"Donald","last_name":"Zack","domain_name":"jhusom","page_name":"DonaldZack","display_name":"Donald Zack","profile_url":"https://jhusom.academia.edu/DonaldZack?f_ri=162553","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=162553","nofollow":false},{"id":10610,"name":"Survival Analysis","url":"https://www.academia.edu/Documents/in/Survival_Analysis?f_ri=162553","nofollow":false},{"id":11298,"name":"Membrane 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development","url":"https://www.academia.edu/Documents/in/Growth_and_development?f_ri=162553"},{"id":117200,"name":"Retina","url":"https://www.academia.edu/Documents/in/Retina?f_ri=162553"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin?f_ri=162553"},{"id":213897,"name":"Phenotype","url":"https://www.academia.edu/Documents/in/Phenotype?f_ri=162553"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=162553"},{"id":534463,"name":"Peroxisome","url":"https://www.academia.edu/Documents/in/Peroxisome?f_ri=162553"},{"id":785265,"name":"Animal Sexual Behavior","url":"https://www.academia.edu/Documents/in/Animal_Sexual_Behavior?f_ri=162553"},{"id":1810445,"name":"Gene expression profiling","url":"https://www.academia.edu/Documents/in/Gene_expression_profiling?f_ri=162553"},{"id":2533047,"name":"fibroblasts","url":"https://www.academia.edu/Documents/in/fibroblasts?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125947561" data-work_id="125947561" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125947561/Exposure_to_PCBs_through_inhalation_dermal_contact_and_dust_ingestion_at_Taizhou_China_A_major_site_for_recycling_transformers">Exposure to PCBs, through inhalation, dermal contact and dust ingestion at Taizhou, China – A major site for recycling transformers</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125947561" data-share-source="work_strip" 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type="text/json">{"id":5104,"name":"Photochemistry","url":"https://www.academia.edu/Documents/in/Photochemistry?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="44526" href="https://www.academia.edu/Documents/in/Feasibility_Study">Feasibility Study</a><script data-card-contents-for-ri="44526" type="text/json">{"id":44526,"name":"Feasibility Study","url":"https://www.academia.edu/Documents/in/Feasibility_Study?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125944890]'), work: {"id":125944890,"title":"Ultrasound measurements of 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href="https://www.academia.edu/125944648/Simple_evaluation_of_the_wound_healing_activity_of_a_crude_extract_of_Portulaca_oleracea_L_growing_in_Jordan_in_Mus_musculus_JVI_1">Simple evaluation of the wound healing activity of a crude extract of Portulaca oleracea L. (growing in Jordan) in Mus musculus JVI-1</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125944648" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="663c511024e73b6456fdf5028dcde6eb" rel="nofollow" data-download="{&quot;attachment_id&quot;:119899184,&quot;asset_id&quot;:125944648,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119899184/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="49142004" href="https://independent.academia.edu/FatmaUlkuYazarAfifi">Fatma Ulku Yazar Afifi</a><script data-card-contents-for-user="49142004" type="text/json">{"id":49142004,"first_name":"Fatma Ulku","last_name":"Yazar Afifi","domain_name":"independent","page_name":"FatmaUlkuYazarAfifi","display_name":"Fatma Ulku Yazar Afifi","profile_url":"https://independent.academia.edu/FatmaUlkuYazarAfifi?f_ri=162553","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_125944648 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125944648"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125944648, container: ".js-paper-rank-work_125944648", }); 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$(".js-view-count[data-work-id=125944648]").text(description); $(".js-view-count-work_125944648").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_125944648").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="125944648"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">16</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="3867" href="https://www.academia.edu/Documents/in/Folk_Medicine">Folk Medicine</a>,&nbsp;<script data-card-contents-for-ri="3867" type="text/json">{"id":3867,"name":"Folk Medicine","url":"https://www.academia.edu/Documents/in/Folk_Medicine?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4083" href="https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine">Complementary and Alternative Medicine</a>,&nbsp;<script data-card-contents-for-ri="4083" type="text/json">{"id":4083,"name":"Complementary and Alternative Medicine","url":"https://www.academia.edu/Documents/in/Complementary_and_Alternative_Medicine?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="5541" href="https://www.academia.edu/Documents/in/Plant_Biology">Plant Biology</a>,&nbsp;<script data-card-contents-for-ri="5541" type="text/json">{"id":5541,"name":"Plant Biology","url":"https://www.academia.edu/Documents/in/Plant_Biology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="8991" href="https://www.academia.edu/Documents/in/Wound_Healing">Wound Healing</a><script data-card-contents-for-ri="8991" type="text/json">{"id":8991,"name":"Wound Healing","url":"https://www.academia.edu/Documents/in/Wound_Healing?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125944648]'), work: {"id":125944648,"title":"Simple evaluation of the wound healing activity of a crude extract of Portulaca oleracea L. 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An immunoperoxidase study using anti</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125944450" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="31cc9e457f7e15837d49eb9ff6ff4acf" rel="nofollow" data-download="{&quot;attachment_id&quot;:119898992,&quot;asset_id&quot;:125944450,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119898992/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33792513" href="https://independent.academia.edu/FelixJTapia">Felix J Tapia</a><script data-card-contents-for-user="33792513" type="text/json">{"id":33792513,"first_name":"Felix","last_name":"Tapia","domain_name":"independent","page_name":"FelixJTapia","display_name":"Felix J Tapia","profile_url":"https://independent.academia.edu/FelixJTapia?f_ri=162553","photo":"https://0.academia-photos.com/33792513/10463986/11675776/s65_felix.tapia.jpg_oh_51d53b64ca3b15c9d5cf0ae3b0b80b75_oe_56bf2e2e___gda___1452466361_95ade53790c4db33b8d48922c7809d77"}</script></span></span></li><li class="js-paper-rank-work_125944450 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125944450"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125944450, container: ".js-paper-rank-work_125944450", }); 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$(".js-view-count[data-work-id=125944450]").text(description); $(".js-view-count-work_125944450").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_125944450").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="125944450"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">10</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a>,&nbsp;<script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12729" href="https://www.academia.edu/Documents/in/Dermatology">Dermatology</a>,&nbsp;<script data-card-contents-for-ri="12729" type="text/json">{"id":12729,"name":"Dermatology","url":"https://www.academia.edu/Documents/in/Dermatology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>,&nbsp;<script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="147196" href="https://www.academia.edu/Documents/in/Monoclonal_Antibodies">Monoclonal Antibodies</a><script data-card-contents-for-ri="147196" type="text/json">{"id":147196,"name":"Monoclonal Antibodies","url":"https://www.academia.edu/Documents/in/Monoclonal_Antibodies?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125944450]'), work: {"id":125944450,"title":"Density of epidermal Langerhans cells in psoriasis patients treated with an aromatic retinoid, RO 10 9359. An immunoperoxidase study using anti","created_at":"2024-11-29T13:37:38.689-08:00","url":"https://www.academia.edu/125944450/Density_of_epidermal_Langerhans_cells_in_psoriasis_patients_treated_with_an_aromatic_retinoid_RO_10_9359_An_immunoperoxidase_study_using_anti?f_ri=162553","dom_id":"work_125944450","summary":null,"downloadable_attachments":[{"id":119898992,"asset_id":125944450,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33792513,"first_name":"Felix","last_name":"Tapia","domain_name":"independent","page_name":"FelixJTapia","display_name":"Felix J Tapia","profile_url":"https://independent.academia.edu/FelixJTapia?f_ri=162553","photo":"https://0.academia-photos.com/33792513/10463986/11675776/s65_felix.tapia.jpg_oh_51d53b64ca3b15c9d5cf0ae3b0b80b75_oe_56bf2e2e___gda___1452466361_95ade53790c4db33b8d48922c7809d77"}],"research_interests":[{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=162553","nofollow":false},{"id":12729,"name":"Dermatology","url":"https://www.academia.edu/Documents/in/Dermatology?f_ri=162553","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553","nofollow":false},{"id":147196,"name":"Monoclonal Antibodies","url":"https://www.academia.edu/Documents/in/Monoclonal_Antibodies?f_ri=162553","nofollow":false},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin?f_ri=162553"},{"id":167295,"name":"Psoriasis","url":"https://www.academia.edu/Documents/in/Psoriasis?f_ri=162553"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=162553"},{"id":852944,"name":"Langerhans cells","url":"https://www.academia.edu/Documents/in/Langerhans_cells?f_ri=162553"},{"id":902717,"name":"Retinoid","url":"https://www.academia.edu/Documents/in/Retinoid?f_ri=162553"},{"id":2796077,"name":"Cell count","url":"https://www.academia.edu/Documents/in/Cell_count?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125941834" data-work_id="125941834" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125941834/EC_NUTRITION_EC_NUTRITION_Research_Article">EC NUTRITION EC NUTRITION Research Article</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The study aimed to assess the efficiency of fruit oil of Pistacia lentiscus for burn wounds healing, anti-inflammatory activity and to evaluate their potential in food industry. Dermal burn healing of fruit oil was evaluated by treating... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125941834" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The study aimed to assess the efficiency of fruit oil of Pistacia lentiscus for burn wounds healing, anti-inflammatory activity and to evaluate their potential in food industry. Dermal burn healing of fruit oil was evaluated by treating burn from random human voluntaries (women and man) using pure oil or ointment 10% of Pistacia lentiscus oil depends on burn degree. Ointment of oil was prepared in the laboratory under supervision of Specialist pharmacist. Phytochemicals content of Oil was determined by thin layer chromatography (TLC) and gas chromatography (GC) techniques. Pure oil of P. lentiscus can be directly applied on dermal burn, or as an ointment contains 10% of P. lentiscus oil. The results showed that oil and ointment oil (10%) accelerated wound healing activity. For dermal inflammatory our result revealed that oil of Pistacia lentiscus can be used in the case of child skin sensitive, eczema, dermal fungi infection, abscess and adult sensitive skin inflammatory. Essential oil and ointment of P. lentiscus contains an active compounds as eugenol, α terpineol, thus engorging wound healing and resistant skin infections. The bioactive compounds found in oil could have potential applications in food, cosmetics, medicine and pharmaceutical product.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125941834" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c05c1d5f5b4e57ed28d883523019f219" rel="nofollow" data-download="{&quot;attachment_id&quot;:119896664,&quot;asset_id&quot;:125941834,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119896664/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="27115922" href="https://misuratau.academia.edu/HudaShaabanElgubbi">Huda Shaaban Elgubbi</a><script data-card-contents-for-user="27115922" type="text/json">{"id":27115922,"first_name":"Huda Shaaban","last_name":"Elgubbi","domain_name":"misuratau","page_name":"HudaShaabanElgubbi","display_name":"Huda Shaaban Elgubbi","profile_url":"https://misuratau.academia.edu/HudaShaabanElgubbi?f_ri=162553","photo":"https://0.academia-photos.com/27115922/7653682/19760339/s65_hudashaaban.ali.jpg"}</script></span></span></li><li class="js-paper-rank-work_125941834 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125941834"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125941834, container: ".js-paper-rank-work_125941834", }); 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$(".js-view-count[data-work-id=125941834]").text(description); $(".js-view-count-work_125941834").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_125941834").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="125941834"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i></div><span class="InlineList-item-text u-textTruncate u-pl6x"><a class="InlineList-item-text" data-has-card-for-ri="156" href="https://www.academia.edu/Documents/in/Genetics">Genetics</a><script data-card-contents-for-ri="156" type="text/json">{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (false) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125941834]'), work: {"id":125941834,"title":"EC NUTRITION EC NUTRITION Research Article","created_at":"2024-11-29T11:01:04.504-08:00","url":"https://www.academia.edu/125941834/EC_NUTRITION_EC_NUTRITION_Research_Article?f_ri=162553","dom_id":"work_125941834","summary":"The study aimed to assess the efficiency of fruit oil of Pistacia lentiscus for burn wounds healing, anti-inflammatory activity and to evaluate their potential in food industry. Dermal burn healing of fruit oil was evaluated by treating burn from random human voluntaries (women and man) using pure oil or ointment 10% of Pistacia lentiscus oil depends on burn degree. Ointment of oil was prepared in the laboratory under supervision of Specialist pharmacist. Phytochemicals content of Oil was determined by thin layer chromatography (TLC) and gas chromatography (GC) techniques. Pure oil of P. lentiscus can be directly applied on dermal burn, or as an ointment contains 10% of P. lentiscus oil. The results showed that oil and ointment oil (10%) accelerated wound healing activity. For dermal inflammatory our result revealed that oil of Pistacia lentiscus can be used in the case of child skin sensitive, eczema, dermal fungi infection, abscess and adult sensitive skin inflammatory. Essential oil and ointment of P. lentiscus contains an active compounds as eugenol, α terpineol, thus engorging wound healing and resistant skin infections. The bioactive compounds found in oil could have potential applications in food, cosmetics, medicine and pharmaceutical product.","downloadable_attachments":[{"id":119896664,"asset_id":125941834,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":27115922,"first_name":"Huda Shaaban","last_name":"Elgubbi","domain_name":"misuratau","page_name":"HudaShaabanElgubbi","display_name":"Huda Shaaban Elgubbi","profile_url":"https://misuratau.academia.edu/HudaShaabanElgubbi?f_ri=162553","photo":"https://0.academia-photos.com/27115922/7653682/19760339/s65_hudashaaban.ali.jpg"}],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=162553","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125939310" data-work_id="125939310" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125939310/Necrosis_digital_inducida_por_gemcitabina_en_una_paciente_con_carcinoma_escamocelular_de_cuello_uterino_reporte_de_un_caso_y_revisi%C3%B3n_de_la_literatura">Necrosis digital inducida por gemcitabina en una paciente con carcinoma escamocelular de cuello uterino: reporte de un caso y revisión de la literatura</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objetivos: presentar el caso de una paciente con carcinoma escamocelular de cuello uterino que desarrolló necrosis distal tras tratamiento con gemcitabina, y realizar una revisión de la literatura para evaluar la asociación entre la dosis... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125939310" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objetivos: presentar el caso de una paciente con carcinoma escamocelular de cuello uterino que desarrolló necrosis distal tras tratamiento con gemcitabina, y realizar una revisión de la literatura para evaluar la asociación entre la dosis acumulada de gemcitabina, el diagnóstico y el manejo de esta complicación. <br /> <br />Materiales y métodos: paciente de 61 años tratada con gemcitabina (11.744 mg/m² acumulados) por enfermedad metastásica, en un hospital general de cuarto nivel, privado, no oncológico, donde venía siendo manejada de forma ambulatoria. Presentó necrosis distal del segundo dedo de la mano derecha, por lo que se suspendió el tratamiento y se requirió amputación de este dedo. Se realizó una búsqueda en Embase, Medline y Lilacs. Se buscaron estudios de reporte y series de casos sobre necrosis distal inducida por gemcitabina. Se extrajeron datos de dosis, diagnóstico y tratamiento. <br /> <br />Resultados: se incluyeron 15 reportes de caso con 19 casos de necrosis distal. Las dosis acumuladas de gemcitabina variaron entre 1.700 y 28.700 mg /m². El diagnóstico fue principalmente clínico, por angiografía y eco-Doppler; el tratamiento incluyó la suspensión de gemcitabina e inicio de vasodilatadores, anticoagulantes y manejo sintomático. <br /> <br />Conclusiones: es fundamental reconocer la toxicidad vascular como un posible efecto adverso de la gemcitabina y realizar una adecuada estratificación del riesgo en pacientes con cáncer avanzado y múltiples líneas de tratamiento previas. Se requiere incrementar la vigilancia de este efecto adverso con el uso de este medicamento.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125939310" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8eb05aa91d7e4f4dc50141c62d9ed175" rel="nofollow" data-download="{&quot;attachment_id&quot;:119894435,&quot;asset_id&quot;:125939310,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen 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type="text/json">{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="651" href="https://www.academia.edu/Documents/in/Plastic_Surgery">Plastic Surgery</a>,&nbsp;<script data-card-contents-for-ri="651" type="text/json">{"id":651,"name":"Plastic Surgery","url":"https://www.academia.edu/Documents/in/Plastic_Surgery?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="8942" href="https://www.academia.edu/Documents/in/Treatment">Treatment</a>,&nbsp;<script data-card-contents-for-ri="8942" type="text/json">{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="10126" href="https://www.academia.edu/Documents/in/Microsurgery">Microsurgery</a><script data-card-contents-for-ri="10126" 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Accidents","url":"https://www.academia.edu/Documents/in/Occupational_Accidents?f_ri=162553"},{"id":1837735,"name":"Scalp","url":"https://www.academia.edu/Documents/in/Scalp?f_ri=162553"},{"id":2125720,"name":"Vein","url":"https://www.academia.edu/Documents/in/Vein?f_ri=162553"},{"id":2432803,"name":"Facial Injuries","url":"https://www.academia.edu/Documents/in/Facial_Injuries?f_ri=162553"},{"id":2592809,"name":"Replantation","url":"https://www.academia.edu/Documents/in/Replantation?f_ri=162553"},{"id":4002193,"name":"Macho","url":"https://www.academia.edu/Documents/in/Macho?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125930346" data-work_id="125930346" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125930346/Development_and_validation_of_HPLC_method_for_imiquimod_determination_in_skin_penetration_studies">Development and validation of HPLC method for imiquimod determination in skin penetration studies</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A simple, rapid and sensitive analytical procedure for the measurement of imiquimod in skin samples after in vitro penetration studies has been developed and validated. In vitro penetration studies were carried out in Franz diffusion... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125930346" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A simple, rapid and sensitive analytical procedure for the measurement of imiquimod in skin samples after in vitro penetration studies has been developed and validated. In vitro penetration studies were carried out in Franz diffusion cells with porcine skin. Tape stripping technique was used to separate the stratum corneum (SC) from the viable epidermis and dermis. Imiquimod was extracted from skin samples using a 7:3 (v/v) methanol:acetate buffer (100 mm, pH 4.0) solution and ultrasonication. Imiquimod was analyzed by HPLC using C8 column and UV detection at 242 nm. The mobile phase used was acetonitrile:acetate buffer (pH 4.0, 100 mm):diethylamine (30:69.85:0.15, v/v) with flow rate 1 mL/min. Imiquimod eluted at 4.1 min and the running time was limited to 6.0 min. The procedure was linear across the following concentration ranges: 100–2500 ng/mL for both SC and tape‐stripped skin and 20–800 ng/mL for receptor solution. Intra‐day and inter‐day accuracy and precision values were low...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125930346" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ca51e6a770c874001c79235b37953e9f" rel="nofollow" data-download="{&quot;attachment_id&quot;:119887058,&quot;asset_id&quot;:125930346,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119887058/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26379860" href="https://haramaya.academia.edu/AhmedAbrahim">Ahmed Abrahim</a><script data-card-contents-for-user="26379860" type="text/json">{"id":26379860,"first_name":"Ahmed","last_name":"Abrahim","domain_name":"haramaya","page_name":"AhmedAbrahim","display_name":"Ahmed Abrahim","profile_url":"https://haramaya.academia.edu/AhmedAbrahim?f_ri=162553","photo":"https://0.academia-photos.com/26379860/87596802/76279304/s65_ahmed.abrahim.png"}</script></span></span></li><li class="js-paper-rank-work_125930346 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125930346"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125930346, container: ".js-paper-rank-work_125930346", }); 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In vitro penetration studies were carried out in Franz diffusion cells with porcine skin. Tape stripping technique was used to separate the stratum corneum (SC) from the viable epidermis and dermis. Imiquimod was extracted from skin samples using a 7:3 (v/v) methanol:acetate buffer (100 mm, pH 4.0) solution and ultrasonication. Imiquimod was analyzed by HPLC using C8 column and UV detection at 242 nm. The mobile phase used was acetonitrile:acetate buffer (pH 4.0, 100 mm):diethylamine (30:69.85:0.15, v/v) with flow rate 1 mL/min. Imiquimod eluted at 4.1 min and the running time was limited to 6.0 min. The procedure was linear across the following concentration ranges: 100–2500 ng/mL for both SC and tape‐stripped skin and 20–800 ng/mL for receptor solution. 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href="https://www.academia.edu/125929324/An_Adult_Case_of_Hydroa_Vacciniforme">An Adult Case of Hydroa Vacciniforme</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">7 : IRANIAN JOURNAL OF DERMATOLOGY SUMMER 2009; 12(2 (48)):64-66. AN ADULT CASE OF HYDROA VACCINIFORME ROUBATI RM*,SAEIDI MARJAN,SARAFIRAD N. * SKIN RESEARCH CENTER, SHOHADA-E ...</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125929324" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7e778cac8b7dbd3e8c60f26375e4ed1d" rel="nofollow" data-download="{&quot;attachment_id&quot;:119886252,&quot;asset_id&quot;:125929324,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119886252/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="329313300" href="https://independent.academia.edu/NimaSarrafirad">Nima Sarrafirad</a><script data-card-contents-for-user="329313300" type="text/json">{"id":329313300,"first_name":"Nima","last_name":"Sarrafirad","domain_name":"independent","page_name":"NimaSarrafirad","display_name":"Nima Sarrafirad","profile_url":"https://independent.academia.edu/NimaSarrafirad?f_ri=162553","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_125929324 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125929324"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125929324, container: ".js-paper-rank-work_125929324", }); 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12(2 (48)):64-66. AN ADULT CASE OF HYDROA VACCINIFORME ROUBATI RM*,SAEIDI MARJAN,SARAFIRAD N. * SKIN RESEARCH CENTER, SHOHADA-E ...","downloadable_attachments":[{"id":119886252,"asset_id":125929324,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":329313300,"first_name":"Nima","last_name":"Sarrafirad","domain_name":"independent","page_name":"NimaSarrafirad","display_name":"Nima Sarrafirad","profile_url":"https://independent.academia.edu/NimaSarrafirad?f_ri=162553","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553","nofollow":false},{"id":894286,"name":"Iranian","url":"https://www.academia.edu/Documents/in/Iranian?f_ri=162553","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125927697" data-work_id="125927697" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125927697/Microvenular_hemangioma_located_in_the_breast_a_case_report">Microvenular hemangioma located in the breast: a case report</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Microvenular hemangioma (MVH) is a rare, benign type of hemangioma that typically presents as a solitary, slow-growing, red-toviolaceous asymptomatic papule, plaque, or nodule. It most commonly locations of the lesions on the limbs and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125927697" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Microvenular hemangioma (MVH) is a rare, benign type of hemangioma that typically presents as a solitary, slow-growing, red-toviolaceous asymptomatic papule, plaque, or nodule. It most commonly locations of the lesions on the limbs and trunk, with no prior reports of MVH confined to the breast. We present the first reported case of multiple MVH confined to the breast in a 17-year-old female patient. The case is notable for its unique and atypical clinical features. Diagnosing MVH is challenging and requires routine pathological and immunohistochemical staining. Histological testing revealed typical features of MVH, irregularly branched small or medium vascular interstitial spaces lined with benign endothelial cells and positivity for CD34 and CD31. This case emphasizes the need to consider MVH in the differential diagnosis of breast vascular lesions, particularly in young patients. It also underscores the importance of histological and immunohistochemical analyses for an accurate diagnosis.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125927697" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3a124715679b5b7f7cdda83d4c9ea349" rel="nofollow" data-download="{&quot;attachment_id&quot;:119884942,&quot;asset_id&quot;:125927697,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119884942/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="312529315" href="https://independent.academia.edu/YeningWang1">Oncology and Translational Medicine</a><script data-card-contents-for-user="312529315" type="text/json">{"id":312529315,"first_name":"Oncology and","last_name":"Translational Medicine","domain_name":"independent","page_name":"YeningWang1","display_name":"Oncology and Translational Medicine","profile_url":"https://independent.academia.edu/YeningWang1?f_ri=162553","photo":"https://0.academia-photos.com/312529315/159391432/149108919/s65_yening.wang.jpeg"}</script></span></span></li><li class="js-paper-rank-work_125927697 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125927697"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125927697, container: ".js-paper-rank-work_125927697", }); 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It most commonly locations of the lesions on the limbs and trunk, with no prior reports of MVH confined to the breast. We present the first reported case of multiple MVH confined to the breast in a 17-year-old female patient. The case is notable for its unique and atypical clinical features. Diagnosing MVH is challenging and requires routine pathological and immunohistochemical staining. Histological testing revealed typical features of MVH, irregularly branched small or medium vascular interstitial spaces lined with benign endothelial cells and positivity for CD34 and CD31. This case emphasizes the need to consider MVH in the differential diagnosis of breast vascular lesions, particularly in young patients. It also underscores the importance of histological and immunohistochemical analyses for an accurate diagnosis.","downloadable_attachments":[{"id":119884942,"asset_id":125927697,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":312529315,"first_name":"Oncology and","last_name":"Translational Medicine","domain_name":"independent","page_name":"YeningWang1","display_name":"Oncology and Translational Medicine","profile_url":"https://independent.academia.edu/YeningWang1?f_ri=162553","photo":"https://0.academia-photos.com/312529315/159391432/149108919/s65_yening.wang.jpeg"}],"research_interests":[{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=162553","nofollow":false},{"id":76863,"name":"Histopathology","url":"https://www.academia.edu/Documents/in/Histopathology?f_ri=162553","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div 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id="dd2539f12e9c6b50570caa970530aec0" rel="nofollow" data-download="{&quot;attachment_id&quot;:119884069,&quot;asset_id&quot;:125926418,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119884069/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" 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Medicine","url":"https://www.academia.edu/Documents/in/Emergency_Medicine?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="12729" href="https://www.academia.edu/Documents/in/Dermatology">Dermatology</a>,&nbsp;<script data-card-contents-for-ri="12729" type="text/json">{"id":12729,"name":"Dermatology","url":"https://www.academia.edu/Documents/in/Dermatology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>,&nbsp;<script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" 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href="https://www.academia.edu/125918099/Crystal_structures_of_wild_type_and_mutated_cyclophilin_B_that_causes_hyperelastosis_cutis_in_the_American_quarter_horse">Crystal structures of wild-type and mutated cyclophilin B that causes hyperelastosis cutis in the American quarter horse</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125918099" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="94c02a7b00944df3cc7d5d5352254805" rel="nofollow" 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$(".js-view-count[data-work-id=125914138]").text(description); $(".js-view-count-work_125914138").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_125914138").removeClass('hidden') })</script></div></li></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125909975" data-work_id="125909975" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125909975/Rare_Malignant_Skin_Tumours_of_the_Head_and_Neck">Rare Malignant Skin Tumours of the Head and Neck</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Introduction: Malignant skin tumors in the majority of cases arise from the squamous epithelium, although they may occur in other accompanying skin structures, such as skin adnexa (hair follicle, sweat and sebaceous glands), as well as... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125909975" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Introduction: Malignant skin tumors in the majority of cases arise from the squamous epithelium, although they may occur in other accompanying skin structures, such as skin adnexa (hair follicle, sweat and sebaceous glands), as well as soft tissues participating in the building of skin structure, such as muscles, fibrous, fatty tissue and cartilagå. Those tumors may also have a neuroendocrine origin or may arise from a premalignant lesion (solar keratosis and lentigo maligna). Regardless of their origin, they usually present as a nodule or longstanding, non-healing ulceration. Their early recognition enhances the treatment results and decreases the possibility of complications (invasion of deeper tissue structures and occurrence of regional and distant metastases). Material and methods: Our retrospective study included 100 patients of both sexes surgically treated for skin malignancy in the Department for Otorhinolaryngology and Maxillofacial surgery of the Clinical Hospital Centre ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125909975" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1ac649853d4615f7ddac76470c8f5e6c" rel="nofollow" data-download="{&quot;attachment_id&quot;:119870295,&quot;asset_id&quot;:125909975,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119870295/download_file?st=MTczMzAzMzQ4Nyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="312244203" href="https://independent.academia.edu/OgnjenCukic">Ognjen Cukic</a><script data-card-contents-for-user="312244203" type="text/json">{"id":312244203,"first_name":"Ognjen","last_name":"Cukic","domain_name":"independent","page_name":"OgnjenCukic","display_name":"Ognjen Cukic","profile_url":"https://independent.academia.edu/OgnjenCukic?f_ri=162553","photo":"https://0.academia-photos.com/312244203/155957097/145583557/s65_ognjen.cukic.png"}</script></span></span></li><li class="js-paper-rank-work_125909975 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125909975"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125909975, container: ".js-paper-rank-work_125909975", }); 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Those tumors may also have a neuroendocrine origin or may arise from a premalignant lesion (solar keratosis and lentigo maligna). Regardless of their origin, they usually present as a nodule or longstanding, non-healing ulceration. Their early recognition enhances the treatment results and decreases the possibility of complications (invasion of deeper tissue structures and occurrence of regional and distant metastases). Material and methods: Our retrospective study included 100 patients of both sexes surgically treated for skin malignancy in the Department for Otorhinolaryngology and Maxillofacial surgery of the Clinical Hospital Centre ...","downloadable_attachments":[{"id":119870295,"asset_id":125909975,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":312244203,"first_name":"Ognjen","last_name":"Cukic","domain_name":"independent","page_name":"OgnjenCukic","display_name":"Ognjen Cukic","profile_url":"https://independent.academia.edu/OgnjenCukic?f_ri=162553","photo":"https://0.academia-photos.com/312244203/155957097/145583557/s65_ognjen.cukic.png"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553","nofollow":false},{"id":53661,"name":"Head and Neck","url":"https://www.academia.edu/Documents/in/Head_and_Neck?f_ri=162553","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div 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href="https://www.academia.edu/125890203/Design_and_evaluation_of_novel_topical_formulation_with_olive_oil_as_natural_functional_active">Design and evaluation of novel topical formulation with olive oil as natural functional active</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Currently, the innovative skin research is focused on the development of novel topical formulations loaded with natural functional actives. The health benefits of olive oil are unsurpassed and many others are revealed as research studies... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125890203" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Currently, the innovative skin research is focused on the development of novel topical formulations loaded with natural functional actives. The health benefits of olive oil are unsurpassed and many others are revealed as research studies allow the understanding of its unlimited properties. Olive oil has a protective toning effect on skin, but it is not transported effectively into its layers. Aiming the development of a cosmetic formulation for skin photoprotection and hydration, we have prepared and characterized macro-sized particles, made of a hydrogel polymer, loaded with olive oil. Alginate beads were uniform in shape, with minimal oil leakage, offering interesting prospects for encapsulation of lipophilic and poorly stable molecules, like olive oil. In vitro photoprotection and in vivo tolerance tests were in favor of this application. Thus, this study suggests that the incorporation of the olive oil-loaded particles into a cream formulation provides strong moisturizing proper...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125890203" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8494c425a523f779a01bcac582066a10" rel="nofollow" data-download="{&quot;attachment_id&quot;:119853715,&quot;asset_id&quot;:125890203,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119853715/download_file?st=MTczMzAzMzQ4OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="309335267" href="https://independent.academia.edu/NicolaiMarisa">Marisa Nicolai</a><script data-card-contents-for-user="309335267" type="text/json">{"id":309335267,"first_name":"Marisa","last_name":"Nicolai","domain_name":"independent","page_name":"NicolaiMarisa","display_name":"Marisa Nicolai","profile_url":"https://independent.academia.edu/NicolaiMarisa?f_ri=162553","photo":"https://0.academia-photos.com/309335267/153486349/143092719/s65_marisa.nicolai.png"}</script></span></span></li><li class="js-paper-rank-work_125890203 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125890203"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125890203, container: ".js-paper-rank-work_125890203", }); 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The health benefits of olive oil are unsurpassed and many others are revealed as research studies allow the understanding of its unlimited properties. Olive oil has a protective toning effect on skin, but it is not transported effectively into its layers. Aiming the development of a cosmetic formulation for skin photoprotection and hydration, we have prepared and characterized macro-sized particles, made of a hydrogel polymer, loaded with olive oil. Alginate beads were uniform in shape, with minimal oil leakage, offering interesting prospects for encapsulation of lipophilic and poorly stable molecules, like olive oil. In vitro photoprotection and in vivo tolerance tests were in favor of this application. 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Lichen Planopilaris / Frontal Fibrosing Alopecia Due to Incidental Chemotherapy for Breast Carcinoma</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125888395" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e571c44ec85487c8dfb3975057e063d1" rel="nofollow" data-download="{&quot;attachment_id&quot;:119852136,&quot;asset_id&quot;:125888395,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button 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type="text/json">{"id":159,"name":"Microbiology","url":"https://www.academia.edu/Documents/in/Microbiology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="6947" href="https://www.academia.edu/Documents/in/Medical_Microbiology">Medical Microbiology</a>,&nbsp;<script data-card-contents-for-ri="6947" type="text/json">{"id":6947,"name":"Medical Microbiology","url":"https://www.academia.edu/Documents/in/Medical_Microbiology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a>,&nbsp;<script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="13919" href="https://www.academia.edu/Documents/in/Fish_Diseases">Fish Diseases</a><script data-card-contents-for-ri="13919" 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pandemic outbreak. Influenza virus-like particles (VLPs) have been suggested as promising vaccine candidates... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125876720" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">ABSTRACTA simple method suitable for self-administration of vaccine would improve mass immunization, particularly during a pandemic outbreak. Influenza virus-like particles (VLPs) have been suggested as promising vaccine candidates against potentially pandemic influenza viruses, as they confer long-lasting immunity but are not infectious. We investigated the immunogenicity and protective efficacy of influenza H5 VLPs containing the hemagglutinin (HA) of A/Vietnam/1203/04 (H5N1) virus delivered into the skin of mice using metal microneedle patches and also studied the response of Langerhans cells in a human skin model. Prime-boost microneedle vaccinations with H5 VLPs elicited higher levels of virus-specific IgG1 and IgG2a antibodies, virus-specific antibody-secreting cells, and cytokine-producing cells up to 8 months after vaccination compared to the same antigen delivered intramuscularly. Both prime-boost microneedle and intramuscular vaccinations with H5 VLPs induced similar hemag...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125876720" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8472ff4bf69eb554c33b70704d639428" rel="nofollow" data-download="{&quot;attachment_id&quot;:119842494,&quot;asset_id&quot;:125876720,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119842494/download_file?st=MTczMzAzMzQ4OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="256140953" href="https://independent.academia.edu/FuShiQuan">Fu-Shi Quan</a><script data-card-contents-for-user="256140953" type="text/json">{"id":256140953,"first_name":"Fu-Shi","last_name":"Quan","domain_name":"independent","page_name":"FuShiQuan","display_name":"Fu-Shi Quan","profile_url":"https://independent.academia.edu/FuShiQuan?f_ri=162553","photo":"https://0.academia-photos.com/256140953/163653701/153449570/s65_fu-shi.quan.png"}</script></span></span></li><li class="js-paper-rank-work_125876720 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125876720"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125876720, container: ".js-paper-rank-work_125876720", }); 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Macromolecules","url":"https://www.academia.edu/Documents/in/Biological_Macromolecules?f_ri=162553"},{"id":1014765,"name":"Phaeophyta","url":"https://www.academia.edu/Documents/in/Phaeophyta?f_ri=162553"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology?f_ri=162553"},{"id":2066316,"name":"Pepsin","url":"https://www.academia.edu/Documents/in/Pepsin?f_ri=162553"},{"id":2764772,"name":"emulsifying agents","url":"https://www.academia.edu/Documents/in/emulsifying_agents?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125873158" data-work_id="125873158" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125873158/Reduced_Inflammation_and_Tissue_Damage_in_Transgenic_Rabbits_Overexpressing_15_Lipoxygenase_and_Endogenous_Anti_inflammatory_Lipid_Mediators">Reduced Inflammation and Tissue Damage in Transgenic Rabbits Overexpressing 15-Lipoxygenase and Endogenous Anti-inflammatory Lipid Mediators</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">PGs and leukotrienes (LTs) mediate cardinal signs of inflammation; hence, their enzymes are targets of current anti-inflammatory therapies. Products of arachidonate 15-lipoxygenases (LO) types I and II display both beneficial roles, such... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125873158" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">PGs and leukotrienes (LTs) mediate cardinal signs of inflammation; hence, their enzymes are targets of current anti-inflammatory therapies. Products of arachidonate 15-lipoxygenases (LO) types I and II display both beneficial roles, such as lipoxins (LXs) that stereoselectively signal counterregulation, as well as potential deleterious actions (i.e., nonspecific phospholipid degradation). In this study, we examined transgenic (TG) rabbits overexpressing 15-LO type I and their response to inflammatory challenge. Skin challenges with either LTB4 or IL-8 showed that 15-LO TG rabbits give markedly reduced neutrophil (PMN) recruitment and plasma leakage at dermal sites with LTB4. PMN from TG rabbits also exhibited a dramatic reduction in LTB4-stimulated granular mobilization that was not evident with peptide chemoattractants. Leukocytes from 15-LO TG rabbits gave enhanced LX production, underscoring differences in lipid mediator profiles compared with non-TG rabbits. Microbe-associated i...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125873158" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0ff40fa888052bc3330fed552450c776" rel="nofollow" data-download="{&quot;attachment_id&quot;:119839569,&quot;asset_id&quot;:125873158,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119839569/download_file?st=MTczMzAzMzQ4OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="73475622" href="https://independent.academia.edu/AshishJain206">Ashish Jain</a><script data-card-contents-for-user="73475622" type="text/json">{"id":73475622,"first_name":"Ashish","last_name":"Jain","domain_name":"independent","page_name":"AshishJain206","display_name":"Ashish Jain","profile_url":"https://independent.academia.edu/AshishJain206?f_ri=162553","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_125873158 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125873158"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125873158, container: ".js-paper-rank-work_125873158", }); 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$(".js-view-count[data-work-id=125873158]").text(description); $(".js-view-count-work_125873158").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_125873158").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="125873158"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>&nbsp;&nbsp;<a class="InlineList-item-text u-positionRelative">13</a>&nbsp;&nbsp;</div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="523" href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a>,&nbsp;<script data-card-contents-for-ri="523" type="text/json">{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1290" href="https://www.academia.edu/Documents/in/Immunology">Immunology</a>,&nbsp;<script data-card-contents-for-ri="1290" type="text/json">{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="9334" href="https://www.academia.edu/Documents/in/Inflammation">Inflammation</a>,&nbsp;<script data-card-contents-for-ri="9334" type="text/json">{"id":9334,"name":"Inflammation","url":"https://www.academia.edu/Documents/in/Inflammation?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="18327" href="https://www.academia.edu/Documents/in/Immunology_of_the_Gut">Immunology of the Gut</a><script data-card-contents-for-ri="18327" type="text/json">{"id":18327,"name":"Immunology of the Gut","url":"https://www.academia.edu/Documents/in/Immunology_of_the_Gut?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125873158]'), work: {"id":125873158,"title":"Reduced Inflammation and Tissue Damage in Transgenic Rabbits Overexpressing 15-Lipoxygenase and Endogenous Anti-inflammatory Lipid Mediators","created_at":"2024-11-26T21:32:41.730-08:00","url":"https://www.academia.edu/125873158/Reduced_Inflammation_and_Tissue_Damage_in_Transgenic_Rabbits_Overexpressing_15_Lipoxygenase_and_Endogenous_Anti_inflammatory_Lipid_Mediators?f_ri=162553","dom_id":"work_125873158","summary":"PGs and leukotrienes (LTs) mediate cardinal signs of inflammation; hence, their enzymes are targets of current anti-inflammatory therapies. Products of arachidonate 15-lipoxygenases (LO) types I and II display both beneficial roles, such as lipoxins (LXs) that stereoselectively signal counterregulation, as well as potential deleterious actions (i.e., nonspecific phospholipid degradation). In this study, we examined transgenic (TG) rabbits overexpressing 15-LO type I and their response to inflammatory challenge. Skin challenges with either LTB4 or IL-8 showed that 15-LO TG rabbits give markedly reduced neutrophil (PMN) recruitment and plasma leakage at dermal sites with LTB4. PMN from TG rabbits also exhibited a dramatic reduction in LTB4-stimulated granular mobilization that was not evident with peptide chemoattractants. Leukocytes from 15-LO TG rabbits gave enhanced LX production, underscoring differences in lipid mediator profiles compared with non-TG rabbits. Microbe-associated i...","downloadable_attachments":[{"id":119839569,"asset_id":125873158,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":73475622,"first_name":"Ashish","last_name":"Jain","domain_name":"independent","page_name":"AshishJain206","display_name":"Ashish Jain","profile_url":"https://independent.academia.edu/AshishJain206?f_ri=162553","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=162553","nofollow":false},{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=162553","nofollow":false},{"id":9334,"name":"Inflammation","url":"https://www.academia.edu/Documents/in/Inflammation?f_ri=162553","nofollow":false},{"id":18327,"name":"Immunology of the Gut","url":"https://www.academia.edu/Documents/in/Immunology_of_the_Gut?f_ri=162553","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553"},{"id":106428,"name":"Eicosanoids","url":"https://www.academia.edu/Documents/in/Eicosanoids?f_ri=162553"},{"id":161176,"name":"The","url":"https://www.academia.edu/Documents/in/The?f_ri=162553"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin?f_ri=162553"},{"id":295260,"name":"Neutrophils","url":"https://www.academia.edu/Documents/in/Neutrophils?f_ri=162553"},{"id":375078,"name":"Topical Drug Administration","url":"https://www.academia.edu/Documents/in/Topical_Drug_Administration?f_ri=162553"},{"id":552210,"name":"Periodontitis","url":"https://www.academia.edu/Documents/in/Periodontitis?f_ri=162553"},{"id":788677,"name":"Rabbits","url":"https://www.academia.edu/Documents/in/Rabbits?f_ri=162553"},{"id":1121353,"name":"Esters","url":"https://www.academia.edu/Documents/in/Esters?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125868135" data-work_id="125868135" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125868135/A_Randomized_Controlled_Trial_of_Incision_and_Drainage_Versus_Ultrasonographically_Guided_Needle_Aspiration_for_Skin_Abscesses_and_the_Effect_of_Methicillin_Resistant_Staphylococcus_aureus">A Randomized Controlled Trial of Incision and Drainage Versus Ultrasonographically Guided Needle Aspiration for Skin Abscesses and the Effect of Methicillin-Resistant Staphylococcus aureus</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125868135" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4d0d84046d8640918a8b4ce52c83e236" 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href="https://independent.academia.edu/MichelleMendoza216">Michelle Mendoza</a><script data-card-contents-for-user="203340462" type="text/json">{"id":203340462,"first_name":"Michelle","last_name":"Mendoza","domain_name":"independent","page_name":"MichelleMendoza216","display_name":"Michelle Mendoza","profile_url":"https://independent.academia.edu/MichelleMendoza216?f_ri=162553","photo":"https://0.academia-photos.com/203340462/64311720/52631369/s65_michelle.mendoza.jpeg"}</script></span></span></li><li class="js-paper-rank-work_125868135 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125868135"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125868135, container: ".js-paper-rank-work_125868135", }); });</script></li><li class="js-percentile-work_125868135 InlineList-item InlineList-item--bordered hidden 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data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>,&nbsp;<script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="23890" href="https://www.academia.edu/Documents/in/Comparative_Study">Comparative Study</a>,&nbsp;<script data-card-contents-for-ri="23890" type="text/json">{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125868135]'), work: {"id":125868135,"title":"A Randomized Controlled Trial of Incision and Drainage Versus Ultrasonographically Guided Needle Aspiration for Skin Abscesses and the Effect of Methicillin-Resistant Staphylococcus aureus","created_at":"2024-11-26T13:59:28.773-08:00","url":"https://www.academia.edu/125868135/A_Randomized_Controlled_Trial_of_Incision_and_Drainage_Versus_Ultrasonographically_Guided_Needle_Aspiration_for_Skin_Abscesses_and_the_Effect_of_Methicillin_Resistant_Staphylococcus_aureus?f_ri=162553","dom_id":"work_125868135","summary":null,"downloadable_attachments":[{"id":119834965,"asset_id":125868135,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":203340462,"first_name":"Michelle","last_name":"Mendoza","domain_name":"independent","page_name":"MichelleMendoza216","display_name":"Michelle Mendoza","profile_url":"https://independent.academia.edu/MichelleMendoza216?f_ri=162553","photo":"https://0.academia-photos.com/203340462/64311720/52631369/s65_michelle.mendoza.jpeg"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=162553","nofollow":false},{"id":12426,"name":"Treatment 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Trial","url":"https://www.academia.edu/Documents/in/Randomized_Controlled_Trial?f_ri=162553"},{"id":424621,"name":"Drainage","url":"https://www.academia.edu/Documents/in/Drainage?f_ri=162553"},{"id":988280,"name":"Abscess","url":"https://www.academia.edu/Documents/in/Abscess?f_ri=162553"},{"id":989950,"name":"Aspiration","url":"https://www.academia.edu/Documents/in/Aspiration?f_ri=162553"},{"id":1381991,"name":"Methicillin Resistant Staphylococcus Aureus","url":"https://www.academia.edu/Documents/in/Methicillin_Resistant_Staphylococcus_Aureus?f_ri=162553"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_125864035" data-work_id="125864035" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125864035/Solution_Blow_Spinning_of_Food_Grade_Gelatin_Nanofibers">Solution Blow Spinning of Food-Grade Gelatin Nanofibers</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The primary advantage of nanofibers over larger diameter fibers is the larger surface area to volume ratio. This study evaluated solution blow spinning (SBS) processing conditions for obtaining food-grade gelatin nanofibers from mammalian... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125864035" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The primary advantage of nanofibers over larger diameter fibers is the larger surface area to volume ratio. This study evaluated solution blow spinning (SBS) processing conditions for obtaining food-grade gelatin nanofibers from mammalian and fishery byproducts, such as pork skin gelatins (PGs) and high molecular weight fish skin gelatin (HMWFG). HMWFG had a highest intact collagen structure compared to PGs. PGs with different Bloom values, solution viscosities, and surface tensions were compared with HMWFG for their ability to produce nanofibers through SBS. Only HMWFG fibers were obtained irrespective of processing conditions, which looked like fluffy cotton candy. HMWFG nanofibers had round morphologies with a narrower diameter distribution and lower average fiber diameter (AFD) under medium gelatin concentrations, medium air pressures, and medium feed rates. The highest glass transition temperature (Tg ) values were obtained at medium concentrations, medium air pressure, and eit...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125864035" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a49f1733ec19c5139a805bff5f94d902" rel="nofollow" data-download="{&quot;attachment_id&quot;:119831344,&quot;asset_id&quot;:125864035,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119831344/download_file?st=MTczMzAzMzQ4OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38211579" href="https://independent.academia.edu/CristinaBilbaosainz">Cristina Bilbao-sainz</a><script data-card-contents-for-user="38211579" type="text/json">{"id":38211579,"first_name":"Cristina","last_name":"Bilbao-sainz","domain_name":"independent","page_name":"CristinaBilbaosainz","display_name":"Cristina Bilbao-sainz","profile_url":"https://independent.academia.edu/CristinaBilbaosainz?f_ri=162553","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_125864035 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125864035"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125864035, container: ".js-paper-rank-work_125864035", }); 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This study evaluated solution blow spinning (SBS) processing conditions for obtaining food-grade gelatin nanofibers from mammalian and fishery byproducts, such as pork skin gelatins (PGs) and high molecular weight fish skin gelatin (HMWFG). HMWFG had a highest intact collagen structure compared to PGs. PGs with different Bloom values, solution viscosities, and surface tensions were compared with HMWFG for their ability to produce nanofibers through SBS. Only HMWFG fibers were obtained irrespective of processing conditions, which looked like fluffy cotton candy. HMWFG nanofibers had round morphologies with a narrower diameter distribution and lower average fiber diameter (AFD) under medium gelatin concentrations, medium air pressures, and medium feed rates. The highest glass transition temperature (Tg ) values were obtained at medium concentrations, medium air pressure, and eit...","downloadable_attachments":[{"id":119831344,"asset_id":125864035,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38211579,"first_name":"Cristina","last_name":"Bilbao-sainz","domain_name":"independent","page_name":"CristinaBilbaosainz","display_name":"Cristina Bilbao-sainz","profile_url":"https://independent.academia.edu/CristinaBilbaosainz?f_ri=162553","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":72,"name":"Chemical Engineering","url":"https://www.academia.edu/Documents/in/Chemical_Engineering?f_ri=162553","nofollow":false},{"id":511,"name":"Materials Science","url":"https://www.academia.edu/Documents/in/Materials_Science?f_ri=162553","nofollow":false},{"id":1040,"name":"Food 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href="https://www.academia.edu/125845023/Coexistent_Linear_Scleroderma_and_Juvenile_Systemic_Lupus_Erythematosus">Coexistent Linear Scleroderma and Juvenile Systemic Lupus Erythematosus</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125845023" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ccc0d1773fd9de9105666f503ee3d670" rel="nofollow" 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data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="498" href="https://www.academia.edu/Documents/in/Physics">Physics</a>,&nbsp;<script data-card-contents-for-ri="498" type="text/json">{"id":498,"name":"Physics","url":"https://www.academia.edu/Documents/in/Physics?f_ri=162553","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="523" href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a><script data-card-contents-for-ri="523" type="text/json">{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=162553","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=125839277]'), work: {"id":125839277,"title":"Cold-induced 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itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/125834083/Mononuclear_Phagocyte_System_Depletion_Blocks_Interstitial_Tonicity_Responsive_Enhancer_Binding_Protein_Vascular_Endothelial_Growth_Factor_C_Expression_and_Induces_Salt_Sensitive_Hypertension_in_Rats">Mononuclear Phagocyte System Depletion Blocks Interstitial Tonicity-Responsive Enhancer Binding Protein/Vascular Endothelial Growth Factor C Expression and Induces Salt-Sensitive Hypertension in Rats</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We showed recently that mononuclear phagocyte system (MPS) cells provide a buffering mechanism for salt-sensitive hypertension by driving interstitial lymphangiogenesis, modulating interstitial Na + clearance, and increasing endothelial... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_125834083" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We showed recently that mononuclear phagocyte system (MPS) cells provide a buffering mechanism for salt-sensitive hypertension by driving interstitial lymphangiogenesis, modulating interstitial Na + clearance, and increasing endothelial NO synthase protein expression in response to very high dietary salt via a tonicity-responsive enhancer binding protein/vascular endothelial growth factor C regulatory mechanism. We now tested whether isotonic saline and deoxycorticosterone acetate (DOCA)-salt treatment leads to a similar regulatory response in Sprague-Dawley rats. Male rats were fed a low-salt diet and received tap water (low-salt diet LSD), 1.0% saline (high-salt diet HSD), or DOCA+1.0% saline (DOCA-HSD). To test the regulatory role of interstitial MPS cells, we further depleted MPS cells with clodronate liposomes. HSD and DOCA-HSD led to Na + accumulation in the skin, MPS-driven tonicity-responsive enhancer binding protein/vascular endothelial growth factor C–mediated hyperplasia ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/125834083" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a6246d46640b61eed8ce9ced6a581c8b" rel="nofollow" data-download="{&quot;attachment_id&quot;:119805345,&quot;asset_id&quot;:125834083,&quot;asset_type&quot;:&quot;Work&quot;,&quot;always_allow_download&quot;:false,&quot;track&quot;:null,&quot;button_location&quot;:&quot;work_strip&quot;,&quot;source&quot;:null,&quot;hide_modal&quot;:null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/119805345/download_file?st=MTczMzAzMzQ4OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by&nbsp;<span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="223904142" href="https://independent.academia.edu/JoonKeunPark">Joon-Keun Park</a><script data-card-contents-for-user="223904142" type="text/json">{"id":223904142,"first_name":"Joon-Keun","last_name":"Park","domain_name":"independent","page_name":"JoonKeunPark","display_name":"Joon-Keun Park","profile_url":"https://independent.academia.edu/JoonKeunPark?f_ri=162553","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_125834083 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="125834083"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 125834083, container: ".js-paper-rank-work_125834083", }); 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We now tested whether isotonic saline and deoxycorticosterone acetate (DOCA)-salt treatment leads to a similar regulatory response in Sprague-Dawley rats. Male rats were fed a low-salt diet and received tap water (low-salt diet LSD), 1.0% saline (high-salt diet HSD), or DOCA+1.0% saline (DOCA-HSD). To test the regulatory role of interstitial MPS cells, we further depleted MPS cells with clodronate liposomes. HSD and DOCA-HSD led to Na + accumulation in the skin, MPS-driven tonicity-responsive enhancer binding protein/vascular endothelial growth factor C–mediated hyperplasia ...","downloadable_attachments":[{"id":119805345,"asset_id":125834083,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":223904142,"first_name":"Joon-Keun","last_name":"Park","domain_name":"independent","page_name":"JoonKeunPark","display_name":"Joon-Keun Park","profile_url":"https://independent.academia.edu/JoonKeunPark?f_ri=162553","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":154,"name":"Endocrinology","url":"https://www.academia.edu/Documents/in/Endocrinology?f_ri=162553","nofollow":false},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=162553","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=162553","nofollow":false},{"id":27784,"name":"Gene 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