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class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://ogu.academia.edu/CCingi"><img class="profile-avatar u-positionAbsolute" alt="Cemal Cingi" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/11477454/3401020/4000156/s200_cemal.cingi.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://ogu.academia.edu/CCingi">Cemal Cingi</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Eskisehir Osmangazi University, Turkey</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://ffst.academia.edu/FraneMihanovic"><img class="profile-avatar u-positionAbsolute" alt="Frane Mihanovic" border="0" onerror="if 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src="https://0.academia-photos.com/33140326/9830881/10955978/s200_mohamed.fahmy.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://alazher.academia.edu/MohamedFahmy">Mohamed Fahmy</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Al Azher</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://utah.academia.edu/NickMamalis"><img class="profile-avatar u-positionAbsolute" border="0" alt="" src="//a.academia-assets.com/images/s200_no_pic.png" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://utah.academia.edu/NickMamalis">Nick Mamalis</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">University of Utah</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://uba.academia.edu/LucasOta%C3%B1o"><img class="profile-avatar u-positionAbsolute" border="0" alt="" src="//a.academia-assets.com/images/s200_no_pic.png" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://uba.academia.edu/LucasOta%C3%B1o">Lucas Otaño</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Universidad de Buenos Aires</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://scuegypt.academia.edu/GoudaEllabban"><img class="profile-avatar u-positionAbsolute" alt="Gouda M El-labban" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" 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Twin Cities</p></div></div></ul></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="46689468" href="https://www.academia.edu/Documents/in/Diabetic_Retinopathy"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://independent.academia.edu/ritaverma5","location":"/ritaverma5","scheme":"https","host":"independent.academia.edu","port":null,"pathname":"/ritaverma5","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Diabetic Retinopathy"]}" data-trace="false" data-dom-id="Pill-react-component-ffe22e30-279b-43ef-aaf6-1ca074375ce0"></div> <div 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id="Pill-react-component-ae5257ba-1122-48eb-87df-516f28957817"></div> </a></div></div></div></div><div class="right-panel-container"><div class="user-content-wrapper"><div class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by rita verma</h3></div><div class="js-work-strip profile--work_container" data-work-id="126383452"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/126383452/Cetirizine_as_a_Causative_Agent_for_Drug_Induced_Methemoglobinemia_A_Case_Report_and_Review"><img alt="Research paper thumbnail of Cetirizine as a Causative Agent for Drug Induced Methemoglobinemia: A Case Report and Review" class="work-thumbnail" src="https://attachments.academia-assets.com/120268279/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/126383452/Cetirizine_as_a_Causative_Agent_for_Drug_Induced_Methemoglobinemia_A_Case_Report_and_Review">Cetirizine as a Causative Agent for Drug Induced Methemoglobinemia: A Case Report and Review</a></div><div class="wp-workCard_item"><span>The journal of pediatric pharmacology and therapeutics</span><span>, Nov 1, 2019</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A case of methemoglobinemia (MHb) in a teenage woman, triggered by an acute ingestion of approxim...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A case of methemoglobinemia (MHb) in a teenage woman, triggered by an acute ingestion of approximately 120 to 180 mg of cetirizine, allegedly, with no suicidal intent is described. The patient presented with anxiety and tremors and rapidly developed central cyanosis unresponsive to oxygen supplementation. There was a history of recurrent, spontaneously remitting, unprovoked "blue discoloration of hands." Investigations confirmed the diagnosis of MHb, and the patient responded to ascorbic acid and methylene blue, although the baseline methemoglobin level remained slightly high. The exact enzymatic deficiency could not be ascertained as the patient refused to undergo complete testing. To the best of our knowledge, this is the first documentation of cetirizine as a causative agent for drug induced MHb. Cetirizine, a selective histamine H1 receptor antagonist is eliminated via oxidation and conjugation processes, which use pathways other than cytochrome P450 enzyme system. The metabolism could potentially create by-products, like superoxide or hydrogen peroxide, which could act as strong reducing agents and oxidize hemoglobin into ferric containing methemoglobin. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="93291333"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/93291333/Hemorrhagic_Disease_Of_Newborn"><img alt="Research paper thumbnail of Hemorrhagic Disease Of Newborn" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/93291333/Hemorrhagic_Disease_Of_Newborn">Hemorrhagic Disease Of Newborn</a></div><div class="wp-workCard_item"><span>StatPearls</span><span>, Jul 3, 2021</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="93291333"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="93291333"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 93291333; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=93291333]").text(description); $(".js-view-count[data-work-id=93291333]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 93291333; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='93291333']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=93291333]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":93291333,"title":"Hemorrhagic Disease Of Newborn","internal_url":"https://www.academia.edu/93291333/Hemorrhagic_Disease_Of_Newborn","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="93291315"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/93291315/A_Rare_Case_Report_of_17q23_1q23_2_Microdeletion_With_Homozygosity_of_11p11_2q13_4_in_a_Newborn"><img alt="Research paper thumbnail of A Rare Case Report of 17q23.1q23.2 Microdeletion With Homozygosity of 11p11.2q13.4 in a Newborn" class="work-thumbnail" src="https://attachments.academia-assets.com/96069062/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/93291315/A_Rare_Case_Report_of_17q23_1q23_2_Microdeletion_With_Homozygosity_of_11p11_2q13_4_in_a_Newborn">A Rare Case Report of 17q23.1q23.2 Microdeletion With Homozygosity of 11p11.2q13.4 in a Newborn</a></div><div class="wp-workCard_item"><span>Cureus</span><span>, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We present the case of a newborn with 17q23.1q23.2 microdeletion and additional homozygosity of 1...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We present the case of a newborn with 17q23.1q23.2 microdeletion and additional homozygosity of 11p11.2q13.4. In the literature, 17q23.1q23.2 microdeletion syndrome is a novel syndrome reported in nine patients. Our patient is a full-term baby boy admitted to a neonatal intensive care unit for hypoglycemia, respiratory distress, presumed sepsis, and thrombocytopenia. General appearance revealed microcephaly, micrognathia, ankyloglossia, small mouth, and high arch palate. The patient also presented with hypotonia, poor feeding, and poor weight gain in the first week of life followed by hypertonia and tremors from the second week of life. The phenotypic and clinical presentation lead to the genetic investigation of microarray which revealed 17q23.1q23.2 microdeletion and additional homozygosity of 11p11.2q13.4.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c402b7adef6be11e66bef613d699f7f9" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":96069062,"asset_id":93291315,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/96069062/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="93291315"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="93291315"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 93291315; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=93291315]").text(description); $(".js-view-count[data-work-id=93291315]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 93291315; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='93291315']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c402b7adef6be11e66bef613d699f7f9" } } $('.js-work-strip[data-work-id=93291315]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":93291315,"title":"A Rare Case Report of 17q23.1q23.2 Microdeletion With Homozygosity of 11p11.2q13.4 in a Newborn","internal_url":"https://www.academia.edu/93291315/A_Rare_Case_Report_of_17q23_1q23_2_Microdeletion_With_Homozygosity_of_11p11_2q13_4_in_a_Newborn","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[{"id":96069062,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/96069062/thumbnails/1.jpg","file_name":"90423-a-rare-case-report-of-17q231q232-microdeletion-with-homozygosity-of-11p112q134-in-a-newborn.pdf","download_url":"https://www.academia.edu/attachments/96069062/download_file","bulk_download_file_name":"A_Rare_Case_Report_of_17q23_1q23_2_Micro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/96069062/90423-a-rare-case-report-of-17q231q232-microdeletion-with-homozygosity-of-11p112q134-in-a-newborn-libre.pdf?1671507872=\u0026response-content-disposition=attachment%3B+filename%3DA_Rare_Case_Report_of_17q23_1q23_2_Micro.pdf\u0026Expires=1740936261\u0026Signature=KBBv3qvkR-9C~rMNQ2e6VZX1o2orRhafeoyPBriEJC1b049nS1gxd7KR~-9FFQcZMFqV18JpaOBdO~8RxU4M3uTPp8RwFBnIhqwAxpo80gh6jmkrDtZupwRgs5JtQP9hcF8cWo~BLnTDCMeFUgbHlawSUzRZpS~d5uqKUbAP4qf-0LxV~qTnF5hqfOU67gJU4qwi91d9tMl7ZOkMFvvfOCQu4q32mvqv-KQQ598981rz2HmOoNO00FhBHwLkY0bpQfzXYlUlBfIlj1bDGP45zWTQByA8KQA71hebf6VDbDw3QiH1hzu0P0ByrUnK0uBtJZyJgnLbxReg0l8G4EXoKQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="86537250"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/86537250/Backlash_South_Asian_immigrant_voices_on_the_margins"><img alt="Research paper thumbnail of Backlash: South Asian immigrant voices on the margins" class="work-thumbnail" src="https://attachments.academia-assets.com/90966399/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/86537250/Backlash_South_Asian_immigrant_voices_on_the_margins">Backlash: South Asian immigrant voices on the margins</a></div><div class="wp-workCard_item"><span>International Studies in Sociology of Education</span><span>, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Neuronal resting potential can tune the excitability of neural networks, affecting downstream beh...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Neuronal resting potential can tune the excitability of neural networks, affecting downstream behavior. Sodium leak channels (NALCN) play a key role in rhythmic behaviors by helping set, or subtly changing neuronal resting potential. The full complexity of these newly described channels is just beginning to be appreciated, however. NALCN channels can associate with numerous subunits in different tissues and can be activated by several different peptides and second messengers. We recently showed that NALCN channels are closely related to fungal calcium channels, which they functionally resemble. Here, we use this relationship to predict a family of NALCN-associated proteins in animals on the basis of homology with the yeast protein Mid1, the subunit of the yeast calcium channel. These proteins all share a cysteine-rich region that is necessary for Mid1 function in yeast. We validate this predicted association by showing that the Mid1 homolog in Drosophila, encoded by the CG33988 gene, is coordinately expressed with NALCN, and that knockdown of either protein creates identical phenotypes in several behaviors associated with NALCN function. The relationship between Mid1 and leak channels has therefore persisted over a billion years of evolution, despite drastic changes to both proteins and the organisms in which they exist.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="1cf5ca5ab7c923f6af440f6e3b41328e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90966399,"asset_id":86537250,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90966399/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="86537250"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="86537250"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 86537250; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=86537250]").text(description); $(".js-view-count[data-work-id=86537250]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 86537250; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='86537250']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992124"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/82992124/Predictability_of_transcutaneous_bilirubinometry_in_late_preterm_and_term_infants_at_risk_for_pathological_hyperbilirubinemia"><img alt="Research paper thumbnail of Predictability of transcutaneous bilirubinometry in late preterm and term infants at risk for pathological hyperbilirubinemia" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/82992124/Predictability_of_transcutaneous_bilirubinometry_in_late_preterm_and_term_infants_at_risk_for_pathological_hyperbilirubinemia">Predictability of transcutaneous bilirubinometry in late preterm and term infants at risk for pathological hyperbilirubinemia</a></div><div class="wp-workCard_item"><span>Journal of neonatal-perinatal medicine</span><span>, 2020</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">BACKGROUND The aim was to assess the predictability of transcutaneous bilirubinometry in late pre...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">BACKGROUND The aim was to assess the predictability of transcutaneous bilirubinometry in late preterm and term neonates at risk for pathological hyperbilirubinemia, and to identify the neonatal population in which transcutaneous bilirubin most accurately predicts serum bilirubin level (SB, mg/dl). METHODS The correlations between transcutaneous bilirubin (TCB, mg/dl) and SB in different neonatal population subsets; and between ΔTSB (TCB-SB) and relevant neonatal variables and clinical groups were analyzed. RESULTS TCB correlated with SB (r = 0.82, p &lt; 0.05) in the cohort (n = 350) and in population subsets (r = 0.81-0.9, p &lt; 0.001). Black infants with gestational age (GA) &gt;35 weeks and chronological age (CA) &gt;3 days recorded strongest correlation (r = 0.9, p &lt; 0.001) followed by Blacks, and non-Black infants with CA &gt;3 days and GA &gt;35 weeks. ΔTSB was positive in Blacks, and in infants with CA &lt;3 days, or with no phototherapy. ΔTSB was negative in non-Black...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992124"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992124"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992124; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=82992124]").text(description); $(".js-view-count[data-work-id=82992124]").attr('title', description).tooltip(); 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</script> <div class="js-work-strip profile--work_container" data-work-id="82992121"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/82992121/Introductory_Chapter_Epidemiology_Evaluation_and_Risk_Assessment_of_Congenital_Anomalies"><img alt="Research paper thumbnail of Introductory Chapter: Epidemiology, Evaluation and Risk Assessment of Congenital Anomalies" class="work-thumbnail" src="https://attachments.academia-assets.com/88502394/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/82992121/Introductory_Chapter_Epidemiology_Evaluation_and_Risk_Assessment_of_Congenital_Anomalies">Introductory Chapter: Epidemiology, Evaluation and Risk Assessment of Congenital Anomalies</a></div><div class="wp-workCard_item"><span>Congenital Anomalies in Newborn Infants - Clinical and Etiopathological Perspectives</span><span>, 2021</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="91ed4930325be325f70dffa1a51fc4de" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":88502394,"asset_id":82992121,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/88502394/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992121"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992121"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992121; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992117"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/82992117/Study_the_Removal_of_Fluoride_from_Aqueous_Medium_by_Using_Nano_Composites"><img alt="Research paper thumbnail of Study the Removal of Fluoride from Aqueous Medium by Using Nano-Composites" class="work-thumbnail" src="https://attachments.academia-assets.com/88502392/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/82992117/Study_the_Removal_of_Fluoride_from_Aqueous_Medium_by_Using_Nano_Composites">Study the Removal of Fluoride from Aqueous Medium by Using Nano-Composites</a></div><div class="wp-workCard_item"><span>Journal of Encapsulation and Adsorption Sciences</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Endemic fluorosis disease has become a major geo-environmental health care issue caused by fluori...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Endemic fluorosis disease has become a major geo-environmental health care issue caused by fluoride ion. High-efficiency and low-cost materials to uptake fluoride from water have been a challenge for scientists and engineers. Here, we report a low-cost process by utilising low-cost starting materials to develop nanocomposite adsorbents for fluoride uptake from water. Bermuda grass as a starting source material converted into nanocomposite carbon fibers upon heat treatment at 800˚C for one hour in Nitrogen atmosphere in the presence of metal oxides. Iron oxide-based nanocomposite (IBNC) is performing high (≈97%) removal of fluoride ion at a contact time of 60 minutes (pH 4) followed by titania-based nanocomposite (TBNC) (≈92%) and micro carbon fiber (≈88%) respectively. The phenomenon of fluoride ion uptake is realised by Freundlich adsorption model, and both adsorption capacity and adsorption intensity for IBNC are higher than those for TBNC and micro carbon fiber.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f1591f4573e5bbdb1f8b72eb480e7187" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":88502392,"asset_id":82992117,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/88502392/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992117"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992117"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992117; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992115"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/82992115/Placental_Histopathology_in_the_Extremely_Low_Birth_Weight_Infants"><img alt="Research paper thumbnail of Placental Histopathology in the Extremely Low Birth Weight Infants" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/82992115/Placental_Histopathology_in_the_Extremely_Low_Birth_Weight_Infants">Placental Histopathology in the Extremely Low Birth Weight Infants</a></div><div class="wp-workCard_item"><span>Fetal & Pediatric Pathology</span><span>, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Our objective was to evaluate the placental histopathology (PH) in extremely low birth weight inf...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Our objective was to evaluate the placental histopathology (PH) in extremely low birth weight infants (ELBW, birth weight &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 1000 g) and to determine if placental histopathological findings are associated with neonatal mortality in them. The PH of all ELBW infants (gestational age 23-30 weeks) born during a 3-year study period was prospectively evaluated and compared with term infants (gestational age &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; or = 37 weeks). Additionally PH of ELBW infants who expired within 28 days of life was compared with those who survived beyond 28 days. Student&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s t test, chi(2) test and Pearson&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s correlation coefficient tests were utilized for data analysis. The occurrences of placental infection (chorioamnionitis, HCA), umbilical cord inflammation (funisitis, vasculitis, and subacute necrotizing funisitis, analyzed collectively as HFV), and abruption were higher in ELBW (n = 105) compared to term infants (n = 61, p = 0.001, 0.0002, and 0.0002, respectively). Placental findings did not differ between the surviving (n = 71) and nonsurviving (n = 51) ELBW infants. Birth weight and gestational age were higher in the surviving group (p = 0.003 and 0.001, respectively). Placental abruption was found more commonly in the presence of HCA and HFV in ELBW infants as opposed to maternal hypertension in term infants. All ELBW placentas with HFV had concomitant findings of HCA whereas only 42% of ELBW placentas with HCA had findings of HFV compared to 24% in term infants (p = 0.09). There was a weak inverse correlation between HCA and birth weight in all (r = - 0.3, p = 0.01) but not in ELBW infants (r = 0.2, p = 0.07). We conclude that placental and umbilical cord inflammation and placental abruption are more commonly present in ELBW compared to term infants. However, these findings do not contribute to neonatal mortality in ELBW infants. Forty-two percent of placental (maternal) inflammation cases have concomitant cord (fetal) inflammation in ELBW infants. Finally HCA correlates inversely with birth weight in neonates.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992115"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992115"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992115; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=82992115]").text(description); $(".js-view-count[data-work-id=82992115]").attr('title', description).tooltip(); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992110"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/82992110/Vitamin_a_Deficiency_and_Severe_Bronchopulmonary_Dysplasia_in_Very_Low_Birth_Weight_Infants"><img alt="Research paper thumbnail of Vitamin a Deficiency and Severe Bronchopulmonary Dysplasia in Very Low Birth Weight Infants" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/82992110/Vitamin_a_Deficiency_and_Severe_Bronchopulmonary_Dysplasia_in_Very_Low_Birth_Weight_Infants">Vitamin a Deficiency and Severe Bronchopulmonary Dysplasia in Very Low Birth Weight Infants</a></div><div class="wp-workCard_item"><span>American Journal of Perinatology</span><span>, 1996</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Preterm infants often have abnormally low serum vitamin A concentrations. Persistence of vitamin ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Preterm infants often have abnormally low serum vitamin A concentrations. Persistence of vitamin A deficiency for a prolonged postnatal period may contribute to the development of bronchopulmonary dysplasia. We retrospectively analyzed data from 22 infants with birthweight &amp;amp;amp;lt; or = 1250 g who had hyaline membrane disease requiring mechanical ventilation with oxygen and in whom serum vitamin A concentrations had been measured at the onset of enteral feeding and every 2 weeks thereafter. Thirteen infants (low serum vitamin A group) had one or more serum vitamin A concentrations &amp;amp;amp;lt; or = 11 mcg/dL at &amp;amp;amp;gt; 10 days of age. In 9 infants (higher serum vitamin A group) all serum vitamin A concentrations were &amp;amp;amp;gt; 11 mcg/dL at &amp;amp;amp;gt; 10 days of age. Mean birthweight, mean gestational age, sex, race, incidence of antenatal maternal glucocorticoid treatment and ventilatory support on the first day of life were similar for the two groups. Severe bronchopulmonary dysplasia was as defined as characteristic radiographic changes and either discharge from the hospital with supplemental oxygen or death from respiratory failure at &amp;amp;amp;gt; 28 days of age following mechanical ventilation with oxygen since birth. The incidence of severe bronchopulmonary dysplasia was significantly higher in the low serum vitamin A group (11/13, 3 deaths vs. 1/9, no deaths; p=0.001). The incidence of pulmonary air leak, the number of ventilator days, the number of days of postnatal glucocorticoid treatment for chronic lung disease, the number of episodes of suspected sepsis and the number of days of antibiotic treatment also were higher in the low serum vitamin A group. Low serum vitamin A group infants were older at the onset of enteral feeding (21 days vs. 8 days; p = 0.001) and during feeding their average daily enteral intake of vitamin A was lower (713 IU vs. 1255 IU; p = 0.001) when compared with infants in the higher serum vitamin A group. Our retrospective analysis of data from these infants confirms earlier reports from other workers that persistent marked vitamin A deficiency in very low birthweight infants is associated with a high incidence of severe bronchopulmonary dysplasia, delayed onset of enteral feeding and low enteral intake of vitamin A.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992110"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992110"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992110; 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It is characterized by the unusual anomaly of ventriculoarterial discordance, with the aorta (A) originating from the right ventricle (RV) and the pulmonary artery (PA) from the left ventricle (LV). In the common Dextro form (DTGA), A is abnormally located to the right, anterior, and inferior of PA. The anatomic configuration results in the lethal hemodynamic pattern of 2 independent and parallel running circulatory circuits, which mandates creating a conduit to ensure the mixing of oxygenated and deoxygenated blood for survival. In the rare Levo form (LTGA), the aorta is placed anterior and to the left of PA with ventricular inversion. TGA is well tolerated in the fetus and is challenging to diagnose by fetal echocardiography unless the outflow tracts are specifically visualized. Postnatally the typical findings of murmur and cyanosis vary according to the associated cardiac de...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c2794a45b065ab3d6cebbbdbb5715ecf" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":83564404,"asset_id":75899695,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/83564404/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="75899695"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="75899695"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 75899695; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=75899695]").text(description); $(".js-view-count[data-work-id=75899695]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 75899695; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='75899695']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c2794a45b065ab3d6cebbbdbb5715ecf" } } $('.js-work-strip[data-work-id=75899695]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":75899695,"title":"Transposition of Great Arteries","internal_url":"https://www.academia.edu/75899695/Transposition_of_Great_Arteries","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[{"id":83564404,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/83564404/thumbnails/1.jpg","file_name":"77846.pdf","download_url":"https://www.academia.edu/attachments/83564404/download_file","bulk_download_file_name":"Transposition_of_Great_Arteries.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/83564404/77846-libre.pdf?1649507338=\u0026response-content-disposition=attachment%3B+filename%3DTransposition_of_Great_Arteries.pdf\u0026Expires=1740951223\u0026Signature=BvAahdvnPQ6LF~7mb-ol1zotsHJTGT1HE9RldzVopJlYZ2sMQp1BS~yLA3T4GS579rUHh8NChnmnJkgOmqLxxLZs3K1gKThZq~Wv30i3Bml7M--OMf~ZI0PbuKU0l9Fn25fKRCNAVKFoRH1UdkHKBK71n6RQEQXoZy7Zp5OIjYyeGUGRp7y4uXz~qZmnGTVY4ZLJXkE34lD0lELO6o6bQ9OL8q8zKsjMzzPAg2Qljq-tpMgK7xA0uMdEwASkFHycFOzXdU6~AnJE0zmY~jvn6KcmCPu8QpdWHIt1v2ST-exzq8aDT4KuuIw24aCuo1E7TCa7CHNIRREJn1e-StQkAQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967991"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65967991/Apnea_in_Preterm_Neonates_A_Review"><img alt="Research paper thumbnail of Apnea in Preterm Neonates: A Review" class="work-thumbnail" src="https://attachments.academia-assets.com/77339193/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65967991/Apnea_in_Preterm_Neonates_A_Review">Apnea in Preterm Neonates: A Review</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Apnea of prematurity (AOP) is one of the commonest clinical conditions encountered in preterm inf...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Apnea of prematurity (AOP) is one of the commonest clinical conditions encountered in preterm infants. With decreasing limit of neonatal viability the subject has become of increasing importance to neonatologists. AOP is a developmental maladaptation to extra uterine life secondary to immature neurological control of breathing. It occurs in 100% cases of extremely low gestational age neonates and in over 50% of all preterm infants. AOP may be associated with adverse outcomes, such as, neurodevelopmental deficits, bronchopulmonary dysplasia and retinopathy of prematurity, although its independent contribution to these morbidities is not fully defined due to the confounding effects of concurrent neonatal pathologies. In this review we have presented the current information on the various aspects of AOP, including its definition, classification, etipathogenesis, clinicalpathophysiological characteristics, management, discharge criteria and potential relationship with post discharge adv...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7027abe94c647101477e7302aaa3b794" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":77339193,"asset_id":65967991,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/77339193/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967991"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967991"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967991; 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dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7027abe94c647101477e7302aaa3b794" } } $('.js-work-strip[data-work-id=65967991]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967991,"title":"Apnea in Preterm Neonates: A Review","internal_url":"https://www.academia.edu/65967991/Apnea_in_Preterm_Neonates_A_Review","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[{"id":77339193,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/77339193/thumbnails/1.jpg","file_name":"325.pdf","download_url":"https://www.academia.edu/attachments/77339193/download_file","bulk_download_file_name":"Apnea_in_Preterm_Neonates_A_Review.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/77339193/325-libre.pdf?1640473346=\u0026response-content-disposition=attachment%3B+filename%3DApnea_in_Preterm_Neonates_A_Review.pdf\u0026Expires=1740936261\u0026Signature=IuC-1YoS7LdtRnTZlDkAlmeI~VsVRoWASJlTJoAsB7ubcIb-vHR4~EG9xkF0svHSL-t7pTINxJpD4d5vhY0XXKm0mnE26ZtTBt72vOnUv4wBUtolWNpqI6NY8xguDKY7giebZUn7APkPFzckT7M3U6OlJcRj08ASQ8y18HmSw88iDGQC~BgbwJsiHQUXK6ldzcuaFebFurNT-6ThdHyod9HfnYsIe8lemlCnIpkG4URmsjArqVFNgUszCBNy3nskaTc6EH45GzEMSiN5oH4-jYUqwAV~RaEcKrFQ0fedQtwoixYDeejhm~5lQrLYZH3Xl4IX2~NleKG2PGivrNZsoA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":77339192,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/77339192/thumbnails/1.jpg","file_name":"325.pdf","download_url":"https://www.academia.edu/attachments/77339192/download_file","bulk_download_file_name":"Apnea_in_Preterm_Neonates_A_Review.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/77339192/325-libre.pdf?1640473346=\u0026response-content-disposition=attachment%3B+filename%3DApnea_in_Preterm_Neonates_A_Review.pdf\u0026Expires=1740936261\u0026Signature=bQteV6U5YjQuFuRIwFiQNdtyuf-sWxtn-cjiApA5dUyGOGr-ULVbzdkeD~v0EF~TBcU96YtEvqeX5UAmgj-TeJVhCw8V6Q35~0UprWi-00x1NTSbG9TZ-2M19L9oNCyiotrqLpCLwfXP4FLgf-GKHogyKTjjYEh6jW3yDYLCu05OeTppr8slpVFKBFJmr-pBNPWsWeCNKmz3A~iTsX-egx6P2d4LHWaVx3VqmYCSnO~eXWg-gh3aXTEWiMkGcmnaDv6q8rlRw2Zl41Z~JsU3qmJ6nGzfW~g96yu8X8KrHYl76Q2FbM7LQsGGJlZpWCEQZWqiYNNTzCY1zWXFHSW0ow__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967990"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/65967990/Clinical_profile_of_early_postnatal_body_weight_changes_in_extremely_low_birth_weight_infants"><img alt="Research paper thumbnail of Clinical profile of early postnatal body weight changes in extremely low birth weight infants" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/65967990/Clinical_profile_of_early_postnatal_body_weight_changes_in_extremely_low_birth_weight_infants">Clinical profile of early postnatal body weight changes in extremely low birth weight infants</a></div><div class="wp-workCard_item"><span>Journal of Neonatal-Perinatal Medicine</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967990"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967990"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967990; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967990]").text(description); $(".js-view-count[data-work-id=65967990]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65967990; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65967990']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=65967990]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967990,"title":"Clinical profile of early postnatal body weight changes in extremely low birth weight infants","internal_url":"https://www.academia.edu/65967990/Clinical_profile_of_early_postnatal_body_weight_changes_in_extremely_low_birth_weight_infants","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967989"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/65967989/Current_Treatment_of_Hypotension_in_ELBW_Infants_Complications_and_Controversies"><img alt="Research paper thumbnail of Current Treatment of Hypotension in ELBW Infants: Complications and Controversies" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/65967989/Current_Treatment_of_Hypotension_in_ELBW_Infants_Complications_and_Controversies">Current Treatment of Hypotension in ELBW Infants: Complications and Controversies</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Anti-hypotensive treatments are often started in response to a low blood pressure (BP) or signs o...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Anti-hypotensive treatments are often started in response to a low blood pressure (BP) or signs of low cardiac output (CO) in critically ill neonates. The challenge for clinicians in the neonatal intensive care unit (NICU) is to dissect out the etiology of the hemodynamic changes, decide if the changes are pathologic or transitionally appropriate, and then tailor the treatment regimen for the patient, the condition, and gestation. This process all occurs while being cognizant that a hemodynamic state evolves throughout the chronological age of the neonate and the course of illness and is affected by concurrent treatments, such as ventilation. Studies in Europe, North America, and Australia all highlight that practices are variable across countries and continents with respect to which patient, when and how to treat with cardiotonic drugs (1–6). A national Canadian database reported that 10% of neonates of &lt;29 weeks had been treated with inotropes on days 1–3 (0–36% within the 27 N...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967989"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967989"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967989; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967989]").text(description); $(".js-view-count[data-work-id=65967989]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65967989; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65967989']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=65967989]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967989,"title":"Current Treatment of Hypotension in ELBW Infants: Complications and Controversies","internal_url":"https://www.academia.edu/65967989/Current_Treatment_of_Hypotension_in_ELBW_Infants_Complications_and_Controversies","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967988"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65967988/Evaluation_and_Risk_Assessment_of_Congenital_Anomalies_in_Neonates"><img alt="Research paper thumbnail of Evaluation and Risk Assessment of Congenital Anomalies in Neonates" class="work-thumbnail" src="https://attachments.academia-assets.com/77339190/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65967988/Evaluation_and_Risk_Assessment_of_Congenital_Anomalies_in_Neonates">Evaluation and Risk Assessment of Congenital Anomalies in Neonates</a></div><div class="wp-workCard_item"><span>Children</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Congenital anomalies (CA) are a large heterogeneous group of disorders of abnormal morphogenesis ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Congenital anomalies (CA) are a large heterogeneous group of disorders of abnormal morphogenesis or biochemistry which present at birth and carry widely variable implications for morbidity and mortality. They are the leading cause of infant mortality in the USA, with an incidence of 3–4% of all births. CA are the fourth leading cause of neonatal mortality worldwide, with an estimated 295,000 deaths annually. The enormous variability in the clinical presentation in terms of severity, time of occurrence, course, complications, management, and outcomes makes the evaluation of CA complicated, highly specific, and individualized. The anomalies can impart tremendous physical, social, and emotional distress on the patient with massive emotional, social, financial, and medical implications for the family and society. The diagnosis may remain elusive despite rigorous, elaborate, and extensive investigations in many cases. While the enormous strides in genetic testing and gene modification th...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="0e255feb1a96a9ecfe74b4ad09b551f4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":77339190,"asset_id":65967988,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/77339190/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967988"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967988"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967988; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967988]").text(description); $(".js-view-count[data-work-id=65967988]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65967988; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65967988']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "0e255feb1a96a9ecfe74b4ad09b551f4" } } $('.js-work-strip[data-work-id=65967988]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967988,"title":"Evaluation and Risk Assessment of Congenital Anomalies in Neonates","internal_url":"https://www.academia.edu/65967988/Evaluation_and_Risk_Assessment_of_Congenital_Anomalies_in_Neonates","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[{"id":77339190,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/77339190/thumbnails/1.jpg","file_name":"pdf.pdf","download_url":"https://www.academia.edu/attachments/77339190/download_file","bulk_download_file_name":"Evaluation_and_Risk_Assessment_of_Congen.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/77339190/pdf-libre.pdf?1640473346=\u0026response-content-disposition=attachment%3B+filename%3DEvaluation_and_Risk_Assessment_of_Congen.pdf\u0026Expires=1740936261\u0026Signature=EE3xbJz9uSST3Fluy4b-OGPI68uDfnloVinG7i4EoISosiPAACzGXB-HC9m0k~EPzIOTi1cdWSDELdH15DkkKIswo4CSy7CvzZDBKHYazFIye774vxNZxqsM6bc~MtYj0prvrOSgQUliT5ZMqwKjLMIk4S1u3FD-vHC5wEPDYoVgzM0Ou0WIDP7~vijFNkS8q43FpPaH5z0~UzigRRK7d8e1xtDLFWdy2a3tuSQvbpfdA4w9xaIujJbJLFgXyo5kRY-omf0d0AHwAHsABVd~LWQ-J3OBbVUNPR1zBlZ68smrjKL3ZXq8O6IMuQN6uiofBAs3vZkkBW6i4v1vIzKkmw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":77339191,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/77339191/thumbnails/1.jpg","file_name":"pdf.pdf","download_url":"https://www.academia.edu/attachments/77339191/download_file","bulk_download_file_name":"Evaluation_and_Risk_Assessment_of_Congen.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/77339191/pdf-libre.pdf?1640473346=\u0026response-content-disposition=attachment%3B+filename%3DEvaluation_and_Risk_Assessment_of_Congen.pdf\u0026Expires=1740936261\u0026Signature=LkIaemyETH-qq9Sw3lwRfPsRG3vLXpfk8QL6sQIi2M57iZLZxYMEhG0qNZxI69k3cyvKEEcl5ngFFcn~ld-UWvE9MDQ1f5Kle3XWerGhLXkkQN7cR9c1L5vAiG632lfQoawOtzaRkCYPmJrz6pHFkFNqvB4FfkoJ2mP~C4nIEdf~PsKlA-16B2pDpAjNNR3vnyTvT7RHA0XtOezy~kBTFV0USGx~wbHbsp0rFc6dpmP51n1Q6zzVYQLU~OoQYb0Xp3tGehswJLKRHqywrJa6~sdLkef3sukXI~PNYfWEsQ1ABF30LvTHhXNOPSDhZmFnvu1-NOrrwN9yfRhRNESQoQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967987"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65967987/Genetics_of_Sirenomelia_the_Mermaid_Syndrome"><img alt="Research paper thumbnail of Genetics of Sirenomelia, the Mermaid Syndrome" class="work-thumbnail" src="https://attachments.academia-assets.com/77339290/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65967987/Genetics_of_Sirenomelia_the_Mermaid_Syndrome">Genetics of Sirenomelia, the Mermaid Syndrome</a></div><div class="wp-workCard_item"><span>Congenital Anomalies in Newborn Infants - Clinical and Etiopathological Perspectives</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Sirenomelia (SML) is a rare, almost universally fatal congenital malformation presenting pathogno...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Sirenomelia (SML) is a rare, almost universally fatal congenital malformation presenting pathognomically with fused lower extremities and absent or malformed perineum. The classic Sirenomelia sequence includes a uniform spectrum of caudal malformations, spinal defects, and a single umbilical artery. SML is postulated to be due to a genetic predisposition, unmasked by biochemical or environmental triggers. Primary developmental defects in the formation of caudal mesoderm or embryonic caudal vessels with resultant local tissue hypoperfusion are proposed hypotheses for its pathogenesis. SML occurs sporadically in humans, presumably due to a spontaneous mutation, and is speculated to have an autosomal dominant inheritance pattern. In mutant mice, specific defects in Cyp26a1 and Bmp 7 genes are demonstrated to produce offsprings with SML. Bmp 7 is a signaling protein, which belongs to the transforming growth factor-β (TGF β) superfamily. Tsg 1, a Bmp and chordin-binding protein, function...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9615c368afe5edd7d1eaf563c7625a4c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":77339290,"asset_id":65967987,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/77339290/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967987"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967987"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967987; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967987]").text(description); $(".js-view-count[data-work-id=65967987]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65967987; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65967987']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967986"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/65967986/Immediate_Postnatal_Microbial_Colonization_in_Sick_Term_Neonates_Admitted_to_NICU_Prevalence_Microbiota_and_Associated_Characteristics"><img alt="Research paper thumbnail of Immediate Postnatal Microbial Colonization in Sick Term Neonates Admitted to NICU: Prevalence, Microbiota, and Associated Characteristics" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/65967986/Immediate_Postnatal_Microbial_Colonization_in_Sick_Term_Neonates_Admitted_to_NICU_Prevalence_Microbiota_and_Associated_Characteristics">Immediate Postnatal Microbial Colonization in Sick Term Neonates Admitted to NICU: Prevalence, Microbiota, and Associated Characteristics</a></div><div class="wp-workCard_item"><span>American Journal of Perinatology</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objective The immediate postnatal rectal (RC) and nasopharyngeal colonization (NPC), their preval...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objective The immediate postnatal rectal (RC) and nasopharyngeal colonization (NPC), their prevalence, taxa, and associated characteristics were investigated in sick term infants admitted to the neonatal intensive care unit. Study Design In a retrospective cohort single center study, nasopharyngeal (NPCx) and rectal (RCx) microbial cultures were obtained within 20 minutes of birth in mild-to- moderate sick term infants. Associations between the colonization and maternal–neonatal variables, including early neonatal course, were analyzed via logistic regression analysis. Results A total of 154 term infants were admitted for respiratory distress, hypoglycemia, maternal chorioamnionitis (CHO), and suspected neonatal sepsis; out of which, 80 (52%) were NPCx-positive (+) infants. The duration of rupture of membrane (ROM) was higher (15.5 ± 10.0 vs. 11.3 ± 11.0 hours, p = 0.02), while the respiratory support requirement (16.3 vs. 29.7%, p = 0.04) and occurrence of maternal group B Streptoc...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967986"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967986"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967986; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967986]").text(description); $(".js-view-count[data-work-id=65967986]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65967986; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65967986']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=65967986]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967986,"title":"Immediate Postnatal Microbial Colonization in Sick Term Neonates Admitted to NICU: Prevalence, Microbiota, and Associated Characteristics","internal_url":"https://www.academia.edu/65967986/Immediate_Postnatal_Microbial_Colonization_in_Sick_Term_Neonates_Admitted_to_NICU_Prevalence_Microbiota_and_Associated_Characteristics","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967985"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65967985/Placental_Histopathology_in_Late_Preterm_infants_Clinical_Implications"><img alt="Research paper thumbnail of Placental Histopathology in Late Preterm infants: Clinical Implications" class="work-thumbnail" src="https://attachments.academia-assets.com/77339188/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65967985/Placental_Histopathology_in_Late_Preterm_infants_Clinical_Implications">Placental Histopathology in Late Preterm infants: Clinical Implications</a></div><div class="wp-workCard_item"><span>Korean Journal of Pediatrics</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: The etiopathogenesis of late preterm (LPT) birth is undetermined. Placental histopath...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: The etiopathogenesis of late preterm (LPT) birth is undetermined. Placental histopathology, which reflects an adverse intrauterine environment and is reportedly associated with preterm labor and neonatal morbidities, has not been studied in LPT infants.Purpose: We investigated placental pathological lesion as markers of an adverse intrauterine environment during LPT labor.Methods: This retrospective case-control study compared placental histopathological and clinical variables between LPT and term neonates. Placental variables included chorioamnionitis, funisitis, hemorrhage, abruption, infarction, calcification, and syncytial knots. Maternal variables included age, substance abuse, pregnancyassociated diabetes mellitus and hypertension, duration of rupture of membrane, antibiotic use, and magnesium sulfate, whereas, those of neonates included gestational age, birth weight, race, sex, and Apgar scores. Standard statistical proedures were applied to analyze the data.Resul...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7731f7373a10e339bcdf49b433851eee" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":77339188,"asset_id":65967985,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/77339188/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967985"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967985"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967985; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967984"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/65967984/Complications_associated_with_the_current_sequential_pharmacological_management_of_early_postnatal_hypotension_in_extremely_premature_infants"><img alt="Research paper thumbnail of Complications associated with the current sequential pharmacological management of early postnatal hypotension in extremely premature infants" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/65967984/Complications_associated_with_the_current_sequential_pharmacological_management_of_early_postnatal_hypotension_in_extremely_premature_infants">Complications associated with the current sequential pharmacological management of early postnatal hypotension in extremely premature infants</a></div><div class="wp-workCard_item"><span>Baylor University Medical Center Proceedings</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Abstract Early postnatal hypotension in premature infants is treated with escalating doses of vas...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Abstract Early postnatal hypotension in premature infants is treated with escalating doses of vasopressor-inotropes (VI), followed by hydrocortisone if VI therapy fails. The adverse effects of this standard clinical practice have not been well reported. In a retrospective case-control study, we compared the complications associated with VI and hydrocortisone (HCVI) treatments in extremely low-birth-weight infants (≤1000 g) with contemporaneous normotensive medication-naïve controls via standard univariate and multivariate analyses. Birth weight, gestational age, and receipt of antenatal steroids did not differ between VI (n = 74) and control (n = 124) groups, while the occurrence of gestational diabetes mellitus and risks for patent ductus arteriosus, intraventricular-periventricular hemorrhage, spontaneous intestinal perforation, ventriculomegaly, and bronchopulmonary dsyplasia were higher in VI. Infants in the HCVI group (n = 69) had lower birth weight, gestational age, and receipt of antenatal steroids and higher risks for intraventricular-periventricular hemorrhage, bronchopulmonary dysplasia, air leaks, and patent ductus arteriosus than controls. Whereas the occurrences of spontaneous intestinal perforation, ventriculomegaly, and maternal diabetes mellitus did not differ, that of maternal hypertension trended to be lower in HCVI recipients (P = 0.06). In conclusion, hypotensive extremely low-birth-weight infants treated with VI or with HCVI are susceptible to intraventricular-periventricular hemorrhage, bronchopulmonary dysplasia, and patent ductus arteriosus. Furthermore, those who receive inotropes are at risk for spontaneous intestinal perforation and ventriculomegaly. Maternal diabetes mellitus increases the occurrence of hypotension, which responds to VI. Maternal hypertension does not contribute to VI responsive and tends to decrease the occurrence of VI-refractory hypotension.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967984"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967984"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967984; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967984]").text(description); 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$a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="11239917" id="papers"><div class="js-work-strip profile--work_container" data-work-id="126383452"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/126383452/Cetirizine_as_a_Causative_Agent_for_Drug_Induced_Methemoglobinemia_A_Case_Report_and_Review"><img alt="Research paper thumbnail of Cetirizine as a Causative Agent for Drug Induced Methemoglobinemia: A Case Report and Review" class="work-thumbnail" src="https://attachments.academia-assets.com/120268279/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/126383452/Cetirizine_as_a_Causative_Agent_for_Drug_Induced_Methemoglobinemia_A_Case_Report_and_Review">Cetirizine as a Causative Agent for Drug Induced Methemoglobinemia: A Case Report and Review</a></div><div class="wp-workCard_item"><span>The journal of pediatric pharmacology and therapeutics</span><span>, Nov 1, 2019</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A case of methemoglobinemia (MHb) in a teenage woman, triggered by an acute ingestion of approxim...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A case of methemoglobinemia (MHb) in a teenage woman, triggered by an acute ingestion of approximately 120 to 180 mg of cetirizine, allegedly, with no suicidal intent is described. The patient presented with anxiety and tremors and rapidly developed central cyanosis unresponsive to oxygen supplementation. There was a history of recurrent, spontaneously remitting, unprovoked "blue discoloration of hands." Investigations confirmed the diagnosis of MHb, and the patient responded to ascorbic acid and methylene blue, although the baseline methemoglobin level remained slightly high. The exact enzymatic deficiency could not be ascertained as the patient refused to undergo complete testing. To the best of our knowledge, this is the first documentation of cetirizine as a causative agent for drug induced MHb. Cetirizine, a selective histamine H1 receptor antagonist is eliminated via oxidation and conjugation processes, which use pathways other than cytochrome P450 enzyme system. The metabolism could potentially create by-products, like superoxide or hydrogen peroxide, which could act as strong reducing agents and oxidize hemoglobin into ferric containing methemoglobin. In this case, an unusually high systemic load of the drug speculatively saturated and overwhelmed the protective enzyme systems, which resulted in clinical manifestation of MHb.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="48eabdd286cdd43316941c81aec137eb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":120268279,"asset_id":126383452,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/120268279/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="126383452"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="126383452"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 126383452; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="93291333"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/93291333/Hemorrhagic_Disease_Of_Newborn"><img alt="Research paper thumbnail of Hemorrhagic Disease Of Newborn" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/93291333/Hemorrhagic_Disease_Of_Newborn">Hemorrhagic Disease Of Newborn</a></div><div class="wp-workCard_item"><span>StatPearls</span><span>, Jul 3, 2021</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="93291333"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="93291333"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 93291333; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=93291333]").text(description); $(".js-view-count[data-work-id=93291333]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 93291333; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='93291333']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=93291333]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":93291333,"title":"Hemorrhagic Disease Of Newborn","internal_url":"https://www.academia.edu/93291333/Hemorrhagic_Disease_Of_Newborn","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="93291315"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/93291315/A_Rare_Case_Report_of_17q23_1q23_2_Microdeletion_With_Homozygosity_of_11p11_2q13_4_in_a_Newborn"><img alt="Research paper thumbnail of A Rare Case Report of 17q23.1q23.2 Microdeletion With Homozygosity of 11p11.2q13.4 in a Newborn" class="work-thumbnail" src="https://attachments.academia-assets.com/96069062/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/93291315/A_Rare_Case_Report_of_17q23_1q23_2_Microdeletion_With_Homozygosity_of_11p11_2q13_4_in_a_Newborn">A Rare Case Report of 17q23.1q23.2 Microdeletion With Homozygosity of 11p11.2q13.4 in a Newborn</a></div><div class="wp-workCard_item"><span>Cureus</span><span>, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">We present the case of a newborn with 17q23.1q23.2 microdeletion and additional homozygosity of 1...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">We present the case of a newborn with 17q23.1q23.2 microdeletion and additional homozygosity of 11p11.2q13.4. In the literature, 17q23.1q23.2 microdeletion syndrome is a novel syndrome reported in nine patients. Our patient is a full-term baby boy admitted to a neonatal intensive care unit for hypoglycemia, respiratory distress, presumed sepsis, and thrombocytopenia. General appearance revealed microcephaly, micrognathia, ankyloglossia, small mouth, and high arch palate. The patient also presented with hypotonia, poor feeding, and poor weight gain in the first week of life followed by hypertonia and tremors from the second week of life. The phenotypic and clinical presentation lead to the genetic investigation of microarray which revealed 17q23.1q23.2 microdeletion and additional homozygosity of 11p11.2q13.4.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c402b7adef6be11e66bef613d699f7f9" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":96069062,"asset_id":93291315,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/96069062/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="93291315"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="93291315"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 93291315; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="86537250"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/86537250/Backlash_South_Asian_immigrant_voices_on_the_margins"><img alt="Research paper thumbnail of Backlash: South Asian immigrant voices on the margins" class="work-thumbnail" src="https://attachments.academia-assets.com/90966399/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/86537250/Backlash_South_Asian_immigrant_voices_on_the_margins">Backlash: South Asian immigrant voices on the margins</a></div><div class="wp-workCard_item"><span>International Studies in Sociology of Education</span><span>, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Neuronal resting potential can tune the excitability of neural networks, affecting downstream beh...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Neuronal resting potential can tune the excitability of neural networks, affecting downstream behavior. Sodium leak channels (NALCN) play a key role in rhythmic behaviors by helping set, or subtly changing neuronal resting potential. The full complexity of these newly described channels is just beginning to be appreciated, however. NALCN channels can associate with numerous subunits in different tissues and can be activated by several different peptides and second messengers. We recently showed that NALCN channels are closely related to fungal calcium channels, which they functionally resemble. Here, we use this relationship to predict a family of NALCN-associated proteins in animals on the basis of homology with the yeast protein Mid1, the subunit of the yeast calcium channel. These proteins all share a cysteine-rich region that is necessary for Mid1 function in yeast. We validate this predicted association by showing that the Mid1 homolog in Drosophila, encoded by the CG33988 gene, is coordinately expressed with NALCN, and that knockdown of either protein creates identical phenotypes in several behaviors associated with NALCN function. The relationship between Mid1 and leak channels has therefore persisted over a billion years of evolution, despite drastic changes to both proteins and the organisms in which they exist.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="1cf5ca5ab7c923f6af440f6e3b41328e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90966399,"asset_id":86537250,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90966399/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="86537250"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="86537250"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 86537250; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=86537250]").text(description); $(".js-view-count[data-work-id=86537250]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 86537250; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='86537250']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992124"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/82992124/Predictability_of_transcutaneous_bilirubinometry_in_late_preterm_and_term_infants_at_risk_for_pathological_hyperbilirubinemia"><img alt="Research paper thumbnail of Predictability of transcutaneous bilirubinometry in late preterm and term infants at risk for pathological hyperbilirubinemia" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/82992124/Predictability_of_transcutaneous_bilirubinometry_in_late_preterm_and_term_infants_at_risk_for_pathological_hyperbilirubinemia">Predictability of transcutaneous bilirubinometry in late preterm and term infants at risk for pathological hyperbilirubinemia</a></div><div class="wp-workCard_item"><span>Journal of neonatal-perinatal medicine</span><span>, 2020</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">BACKGROUND The aim was to assess the predictability of transcutaneous bilirubinometry in late pre...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">BACKGROUND The aim was to assess the predictability of transcutaneous bilirubinometry in late preterm and term neonates at risk for pathological hyperbilirubinemia, and to identify the neonatal population in which transcutaneous bilirubin most accurately predicts serum bilirubin level (SB, mg/dl). METHODS The correlations between transcutaneous bilirubin (TCB, mg/dl) and SB in different neonatal population subsets; and between ΔTSB (TCB-SB) and relevant neonatal variables and clinical groups were analyzed. RESULTS TCB correlated with SB (r = 0.82, p &lt; 0.05) in the cohort (n = 350) and in population subsets (r = 0.81-0.9, p &lt; 0.001). Black infants with gestational age (GA) &gt;35 weeks and chronological age (CA) &gt;3 days recorded strongest correlation (r = 0.9, p &lt; 0.001) followed by Blacks, and non-Black infants with CA &gt;3 days and GA &gt;35 weeks. ΔTSB was positive in Blacks, and in infants with CA &lt;3 days, or with no phototherapy. ΔTSB was negative in non-Black...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992124"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992124"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992124; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=82992124]").text(description); $(".js-view-count[data-work-id=82992124]").attr('title', description).tooltip(); 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</script> <div class="js-work-strip profile--work_container" data-work-id="82992121"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/82992121/Introductory_Chapter_Epidemiology_Evaluation_and_Risk_Assessment_of_Congenital_Anomalies"><img alt="Research paper thumbnail of Introductory Chapter: Epidemiology, Evaluation and Risk Assessment of Congenital Anomalies" class="work-thumbnail" src="https://attachments.academia-assets.com/88502394/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/82992121/Introductory_Chapter_Epidemiology_Evaluation_and_Risk_Assessment_of_Congenital_Anomalies">Introductory Chapter: Epidemiology, Evaluation and Risk Assessment of Congenital Anomalies</a></div><div class="wp-workCard_item"><span>Congenital Anomalies in Newborn Infants - Clinical and Etiopathological Perspectives</span><span>, 2021</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="91ed4930325be325f70dffa1a51fc4de" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":88502394,"asset_id":82992121,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/88502394/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992121"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992121"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992121; 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dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "91ed4930325be325f70dffa1a51fc4de" } } $('.js-work-strip[data-work-id=82992121]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":82992121,"title":"Introductory Chapter: Epidemiology, Evaluation and Risk Assessment of Congenital Anomalies","internal_url":"https://www.academia.edu/82992121/Introductory_Chapter_Epidemiology_Evaluation_and_Risk_Assessment_of_Congenital_Anomalies","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[{"id":88502394,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/88502394/thumbnails/1.jpg","file_name":"76121.pdf","download_url":"https://www.academia.edu/attachments/88502394/download_file","bulk_download_file_name":"Introductory_Chapter_Epidemiology_Evalua.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/88502394/76121-libre.pdf?1657628473=\u0026response-content-disposition=attachment%3B+filename%3DIntroductory_Chapter_Epidemiology_Evalua.pdf\u0026Expires=1740936261\u0026Signature=LixBX7qc6FYAGVd5dgv0Y3bc48p3sAXaQDnDnJI8~gm3q1NWmxgfkI2un5HesEhQTUpBQl1h~HZX0C5a6cXwxOx40eU2zWpnQbkXCMuaMNcK939xYuKvJrgDd8B2BNkWUSfxRrN0z86xFDk2xCWTYWPevKf09CJH1R8QU5ufrt~oo92OTI~qQObWJfMF8EMwktZdVx4k-jQXPx9eAwoT19QEiVqwtxV8nofh8l1oJSIPY~xVDlrHrntYYhCb2bjv901yAsNQwk2j-YnkW3z4b84wgCgDfyg3ClPmFOFBzAuJbcUmiECFpsKIJVAEKFVl5i3ihHshnHG~L~MkTYGBpg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992117"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/82992117/Study_the_Removal_of_Fluoride_from_Aqueous_Medium_by_Using_Nano_Composites"><img alt="Research paper thumbnail of Study the Removal of Fluoride from Aqueous Medium by Using Nano-Composites" class="work-thumbnail" src="https://attachments.academia-assets.com/88502392/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/82992117/Study_the_Removal_of_Fluoride_from_Aqueous_Medium_by_Using_Nano_Composites">Study the Removal of Fluoride from Aqueous Medium by Using Nano-Composites</a></div><div class="wp-workCard_item"><span>Journal of Encapsulation and Adsorption Sciences</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Endemic fluorosis disease has become a major geo-environmental health care issue caused by fluori...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Endemic fluorosis disease has become a major geo-environmental health care issue caused by fluoride ion. High-efficiency and low-cost materials to uptake fluoride from water have been a challenge for scientists and engineers. Here, we report a low-cost process by utilising low-cost starting materials to develop nanocomposite adsorbents for fluoride uptake from water. Bermuda grass as a starting source material converted into nanocomposite carbon fibers upon heat treatment at 800˚C for one hour in Nitrogen atmosphere in the presence of metal oxides. Iron oxide-based nanocomposite (IBNC) is performing high (≈97%) removal of fluoride ion at a contact time of 60 minutes (pH 4) followed by titania-based nanocomposite (TBNC) (≈92%) and micro carbon fiber (≈88%) respectively. The phenomenon of fluoride ion uptake is realised by Freundlich adsorption model, and both adsorption capacity and adsorption intensity for IBNC are higher than those for TBNC and micro carbon fiber.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f1591f4573e5bbdb1f8b72eb480e7187" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":88502392,"asset_id":82992117,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/88502392/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992117"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992117"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992117; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=82992117]").text(description); $(".js-view-count[data-work-id=82992117]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 82992117; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='82992117']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992115"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/82992115/Placental_Histopathology_in_the_Extremely_Low_Birth_Weight_Infants"><img alt="Research paper thumbnail of Placental Histopathology in the Extremely Low Birth Weight Infants" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/82992115/Placental_Histopathology_in_the_Extremely_Low_Birth_Weight_Infants">Placental Histopathology in the Extremely Low Birth Weight Infants</a></div><div class="wp-workCard_item"><span>Fetal & Pediatric Pathology</span><span>, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Our objective was to evaluate the placental histopathology (PH) in extremely low birth weight inf...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Our objective was to evaluate the placental histopathology (PH) in extremely low birth weight infants (ELBW, birth weight &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 1000 g) and to determine if placental histopathological findings are associated with neonatal mortality in them. The PH of all ELBW infants (gestational age 23-30 weeks) born during a 3-year study period was prospectively evaluated and compared with term infants (gestational age &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; or = 37 weeks). Additionally PH of ELBW infants who expired within 28 days of life was compared with those who survived beyond 28 days. Student&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s t test, chi(2) test and Pearson&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s correlation coefficient tests were utilized for data analysis. The occurrences of placental infection (chorioamnionitis, HCA), umbilical cord inflammation (funisitis, vasculitis, and subacute necrotizing funisitis, analyzed collectively as HFV), and abruption were higher in ELBW (n = 105) compared to term infants (n = 61, p = 0.001, 0.0002, and 0.0002, respectively). Placental findings did not differ between the surviving (n = 71) and nonsurviving (n = 51) ELBW infants. Birth weight and gestational age were higher in the surviving group (p = 0.003 and 0.001, respectively). Placental abruption was found more commonly in the presence of HCA and HFV in ELBW infants as opposed to maternal hypertension in term infants. All ELBW placentas with HFV had concomitant findings of HCA whereas only 42% of ELBW placentas with HCA had findings of HFV compared to 24% in term infants (p = 0.09). There was a weak inverse correlation between HCA and birth weight in all (r = - 0.3, p = 0.01) but not in ELBW infants (r = 0.2, p = 0.07). We conclude that placental and umbilical cord inflammation and placental abruption are more commonly present in ELBW compared to term infants. However, these findings do not contribute to neonatal mortality in ELBW infants. Forty-two percent of placental (maternal) inflammation cases have concomitant cord (fetal) inflammation in ELBW infants. Finally HCA correlates inversely with birth weight in neonates.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992115"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992115"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992115; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=82992115]").text(description); $(".js-view-count[data-work-id=82992115]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 82992115; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='82992115']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=82992115]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":82992115,"title":"Placental Histopathology in the Extremely Low Birth Weight Infants","internal_url":"https://www.academia.edu/82992115/Placental_Histopathology_in_the_Extremely_Low_Birth_Weight_Infants","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992112"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/82992112/Respiratory_Distress_Syndrome_of_Newborn_Infants"><img alt="Research paper thumbnail of Respiratory Distress Syndrome of Newborn Infants" class="work-thumbnail" src="https://attachments.academia-assets.com/88502388/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/82992112/Respiratory_Distress_Syndrome_of_Newborn_Infants">Respiratory Distress Syndrome of Newborn Infants</a></div><div class="wp-workCard_item"><span>Clinical Pediatrics</span><span>, 1970</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c58f2b3aba77cb6070d3d44c9c4ce8f7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":88502388,"asset_id":82992112,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/88502388/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992112"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992112"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992112; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=82992112]").text(description); $(".js-view-count[data-work-id=82992112]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 82992112; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='82992112']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c58f2b3aba77cb6070d3d44c9c4ce8f7" } } $('.js-work-strip[data-work-id=82992112]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":82992112,"title":"Respiratory Distress Syndrome of Newborn Infants","internal_url":"https://www.academia.edu/82992112/Respiratory_Distress_Syndrome_of_Newborn_Infants","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[{"id":88502388,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/88502388/thumbnails/1.jpg","file_name":"00006254-196302000-0001520220712-1-jysbq1.pdf","download_url":"https://www.academia.edu/attachments/88502388/download_file","bulk_download_file_name":"Respiratory_Distress_Syndrome_of_Newborn.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/88502388/00006254-196302000-0001520220712-1-jysbq1-libre.pdf?1657628471=\u0026response-content-disposition=attachment%3B+filename%3DRespiratory_Distress_Syndrome_of_Newborn.pdf\u0026Expires=1740936261\u0026Signature=PMig9M7o9CqHKu4SLQMF5jrjZUdM16LdknqXyfVifZ7RtfrYFXS5y5uw6wIGfNBzYXBp6kv7URzMlg4k344MEItdnOCy3tMf8xnfK-OS1MCK5re4Na3sq026T~T6h1Thk45RvfGsbRtFIyJX7OXoHfXfLCTTDUlyaxyTYcDwko~MLHL2Mtu8Q8ae7tXpPrCzrZyRRH6PKOVqemCvA0nhJDz6a7s6mYaYdEQgX3S0J28syq16tuCDsnmJ7l-vXGqgsgKjLq3B5AKPp0Jcjv3n8L~u9Xk6T-ds5ffF~FTRai6TBxz4lb2z~BbEJ71HDRmVBMTxfR7LrJHy~XQVgYGViw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="82992110"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/82992110/Vitamin_a_Deficiency_and_Severe_Bronchopulmonary_Dysplasia_in_Very_Low_Birth_Weight_Infants"><img alt="Research paper thumbnail of Vitamin a Deficiency and Severe Bronchopulmonary Dysplasia in Very Low Birth Weight Infants" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/82992110/Vitamin_a_Deficiency_and_Severe_Bronchopulmonary_Dysplasia_in_Very_Low_Birth_Weight_Infants">Vitamin a Deficiency and Severe Bronchopulmonary Dysplasia in Very Low Birth Weight Infants</a></div><div class="wp-workCard_item"><span>American Journal of Perinatology</span><span>, 1996</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Preterm infants often have abnormally low serum vitamin A concentrations. Persistence of vitamin ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Preterm infants often have abnormally low serum vitamin A concentrations. Persistence of vitamin A deficiency for a prolonged postnatal period may contribute to the development of bronchopulmonary dysplasia. We retrospectively analyzed data from 22 infants with birthweight &amp;amp;amp;lt; or = 1250 g who had hyaline membrane disease requiring mechanical ventilation with oxygen and in whom serum vitamin A concentrations had been measured at the onset of enteral feeding and every 2 weeks thereafter. Thirteen infants (low serum vitamin A group) had one or more serum vitamin A concentrations &amp;amp;amp;lt; or = 11 mcg/dL at &amp;amp;amp;gt; 10 days of age. In 9 infants (higher serum vitamin A group) all serum vitamin A concentrations were &amp;amp;amp;gt; 11 mcg/dL at &amp;amp;amp;gt; 10 days of age. Mean birthweight, mean gestational age, sex, race, incidence of antenatal maternal glucocorticoid treatment and ventilatory support on the first day of life were similar for the two groups. Severe bronchopulmonary dysplasia was as defined as characteristic radiographic changes and either discharge from the hospital with supplemental oxygen or death from respiratory failure at &amp;amp;amp;gt; 28 days of age following mechanical ventilation with oxygen since birth. The incidence of severe bronchopulmonary dysplasia was significantly higher in the low serum vitamin A group (11/13, 3 deaths vs. 1/9, no deaths; p=0.001). The incidence of pulmonary air leak, the number of ventilator days, the number of days of postnatal glucocorticoid treatment for chronic lung disease, the number of episodes of suspected sepsis and the number of days of antibiotic treatment also were higher in the low serum vitamin A group. Low serum vitamin A group infants were older at the onset of enteral feeding (21 days vs. 8 days; p = 0.001) and during feeding their average daily enteral intake of vitamin A was lower (713 IU vs. 1255 IU; p = 0.001) when compared with infants in the higher serum vitamin A group. Our retrospective analysis of data from these infants confirms earlier reports from other workers that persistent marked vitamin A deficiency in very low birthweight infants is associated with a high incidence of severe bronchopulmonary dysplasia, delayed onset of enteral feeding and low enteral intake of vitamin A.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82992110"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82992110"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82992110; 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It is characterized by the unusual anomaly of ventriculoarterial discordance, with the aorta (A) originating from the right ventricle (RV) and the pulmonary artery (PA) from the left ventricle (LV). In the common Dextro form (DTGA), A is abnormally located to the right, anterior, and inferior of PA. The anatomic configuration results in the lethal hemodynamic pattern of 2 independent and parallel running circulatory circuits, which mandates creating a conduit to ensure the mixing of oxygenated and deoxygenated blood for survival. In the rare Levo form (LTGA), the aorta is placed anterior and to the left of PA with ventricular inversion. TGA is well tolerated in the fetus and is challenging to diagnose by fetal echocardiography unless the outflow tracts are specifically visualized. Postnatally the typical findings of murmur and cyanosis vary according to the associated cardiac de...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c2794a45b065ab3d6cebbbdbb5715ecf" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":83564404,"asset_id":75899695,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/83564404/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="75899695"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="75899695"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 75899695; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967991"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65967991/Apnea_in_Preterm_Neonates_A_Review"><img alt="Research paper thumbnail of Apnea in Preterm Neonates: A Review" class="work-thumbnail" src="https://attachments.academia-assets.com/77339193/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65967991/Apnea_in_Preterm_Neonates_A_Review">Apnea in Preterm Neonates: A Review</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Apnea of prematurity (AOP) is one of the commonest clinical conditions encountered in preterm inf...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Apnea of prematurity (AOP) is one of the commonest clinical conditions encountered in preterm infants. With decreasing limit of neonatal viability the subject has become of increasing importance to neonatologists. AOP is a developmental maladaptation to extra uterine life secondary to immature neurological control of breathing. It occurs in 100% cases of extremely low gestational age neonates and in over 50% of all preterm infants. AOP may be associated with adverse outcomes, such as, neurodevelopmental deficits, bronchopulmonary dysplasia and retinopathy of prematurity, although its independent contribution to these morbidities is not fully defined due to the confounding effects of concurrent neonatal pathologies. In this review we have presented the current information on the various aspects of AOP, including its definition, classification, etipathogenesis, clinicalpathophysiological characteristics, management, discharge criteria and potential relationship with post discharge adv...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7027abe94c647101477e7302aaa3b794" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":77339193,"asset_id":65967991,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/77339193/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967991"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967991"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967991; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967990"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/65967990/Clinical_profile_of_early_postnatal_body_weight_changes_in_extremely_low_birth_weight_infants"><img alt="Research paper thumbnail of Clinical profile of early postnatal body weight changes in extremely low birth weight infants" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/65967990/Clinical_profile_of_early_postnatal_body_weight_changes_in_extremely_low_birth_weight_infants">Clinical profile of early postnatal body weight changes in extremely low birth weight infants</a></div><div class="wp-workCard_item"><span>Journal of Neonatal-Perinatal Medicine</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967990"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967990"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967990; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967990]").text(description); $(".js-view-count[data-work-id=65967990]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65967990; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65967990']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=65967990]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967990,"title":"Clinical profile of early postnatal body weight changes in extremely low birth weight infants","internal_url":"https://www.academia.edu/65967990/Clinical_profile_of_early_postnatal_body_weight_changes_in_extremely_low_birth_weight_infants","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967989"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/65967989/Current_Treatment_of_Hypotension_in_ELBW_Infants_Complications_and_Controversies"><img alt="Research paper thumbnail of Current Treatment of Hypotension in ELBW Infants: Complications and Controversies" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/65967989/Current_Treatment_of_Hypotension_in_ELBW_Infants_Complications_and_Controversies">Current Treatment of Hypotension in ELBW Infants: Complications and Controversies</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Anti-hypotensive treatments are often started in response to a low blood pressure (BP) or signs o...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Anti-hypotensive treatments are often started in response to a low blood pressure (BP) or signs of low cardiac output (CO) in critically ill neonates. The challenge for clinicians in the neonatal intensive care unit (NICU) is to dissect out the etiology of the hemodynamic changes, decide if the changes are pathologic or transitionally appropriate, and then tailor the treatment regimen for the patient, the condition, and gestation. This process all occurs while being cognizant that a hemodynamic state evolves throughout the chronological age of the neonate and the course of illness and is affected by concurrent treatments, such as ventilation. Studies in Europe, North America, and Australia all highlight that practices are variable across countries and continents with respect to which patient, when and how to treat with cardiotonic drugs (1–6). A national Canadian database reported that 10% of neonates of &lt;29 weeks had been treated with inotropes on days 1–3 (0–36% within the 27 N...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967989"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967989"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967989; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967989]").text(description); $(".js-view-count[data-work-id=65967989]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65967989; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65967989']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=65967989]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967989,"title":"Current Treatment of Hypotension in ELBW Infants: Complications and Controversies","internal_url":"https://www.academia.edu/65967989/Current_Treatment_of_Hypotension_in_ELBW_Infants_Complications_and_Controversies","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967988"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65967988/Evaluation_and_Risk_Assessment_of_Congenital_Anomalies_in_Neonates"><img alt="Research paper thumbnail of Evaluation and Risk Assessment of Congenital Anomalies in Neonates" class="work-thumbnail" src="https://attachments.academia-assets.com/77339190/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65967988/Evaluation_and_Risk_Assessment_of_Congenital_Anomalies_in_Neonates">Evaluation and Risk Assessment of Congenital Anomalies in Neonates</a></div><div class="wp-workCard_item"><span>Children</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Congenital anomalies (CA) are a large heterogeneous group of disorders of abnormal morphogenesis ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Congenital anomalies (CA) are a large heterogeneous group of disorders of abnormal morphogenesis or biochemistry which present at birth and carry widely variable implications for morbidity and mortality. They are the leading cause of infant mortality in the USA, with an incidence of 3–4% of all births. CA are the fourth leading cause of neonatal mortality worldwide, with an estimated 295,000 deaths annually. The enormous variability in the clinical presentation in terms of severity, time of occurrence, course, complications, management, and outcomes makes the evaluation of CA complicated, highly specific, and individualized. The anomalies can impart tremendous physical, social, and emotional distress on the patient with massive emotional, social, financial, and medical implications for the family and society. The diagnosis may remain elusive despite rigorous, elaborate, and extensive investigations in many cases. While the enormous strides in genetic testing and gene modification th...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="0e255feb1a96a9ecfe74b4ad09b551f4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":77339190,"asset_id":65967988,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/77339190/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967988"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967988"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967988; 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dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "0e255feb1a96a9ecfe74b4ad09b551f4" } } $('.js-work-strip[data-work-id=65967988]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967988,"title":"Evaluation and Risk Assessment of Congenital Anomalies in Neonates","internal_url":"https://www.academia.edu/65967988/Evaluation_and_Risk_Assessment_of_Congenital_Anomalies_in_Neonates","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[{"id":77339190,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/77339190/thumbnails/1.jpg","file_name":"pdf.pdf","download_url":"https://www.academia.edu/attachments/77339190/download_file","bulk_download_file_name":"Evaluation_and_Risk_Assessment_of_Congen.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/77339190/pdf-libre.pdf?1640473346=\u0026response-content-disposition=attachment%3B+filename%3DEvaluation_and_Risk_Assessment_of_Congen.pdf\u0026Expires=1740936261\u0026Signature=EE3xbJz9uSST3Fluy4b-OGPI68uDfnloVinG7i4EoISosiPAACzGXB-HC9m0k~EPzIOTi1cdWSDELdH15DkkKIswo4CSy7CvzZDBKHYazFIye774vxNZxqsM6bc~MtYj0prvrOSgQUliT5ZMqwKjLMIk4S1u3FD-vHC5wEPDYoVgzM0Ou0WIDP7~vijFNkS8q43FpPaH5z0~UzigRRK7d8e1xtDLFWdy2a3tuSQvbpfdA4w9xaIujJbJLFgXyo5kRY-omf0d0AHwAHsABVd~LWQ-J3OBbVUNPR1zBlZ68smrjKL3ZXq8O6IMuQN6uiofBAs3vZkkBW6i4v1vIzKkmw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":77339191,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/77339191/thumbnails/1.jpg","file_name":"pdf.pdf","download_url":"https://www.academia.edu/attachments/77339191/download_file","bulk_download_file_name":"Evaluation_and_Risk_Assessment_of_Congen.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/77339191/pdf-libre.pdf?1640473346=\u0026response-content-disposition=attachment%3B+filename%3DEvaluation_and_Risk_Assessment_of_Congen.pdf\u0026Expires=1740936261\u0026Signature=LkIaemyETH-qq9Sw3lwRfPsRG3vLXpfk8QL6sQIi2M57iZLZxYMEhG0qNZxI69k3cyvKEEcl5ngFFcn~ld-UWvE9MDQ1f5Kle3XWerGhLXkkQN7cR9c1L5vAiG632lfQoawOtzaRkCYPmJrz6pHFkFNqvB4FfkoJ2mP~C4nIEdf~PsKlA-16B2pDpAjNNR3vnyTvT7RHA0XtOezy~kBTFV0USGx~wbHbsp0rFc6dpmP51n1Q6zzVYQLU~OoQYb0Xp3tGehswJLKRHqywrJa6~sdLkef3sukXI~PNYfWEsQ1ABF30LvTHhXNOPSDhZmFnvu1-NOrrwN9yfRhRNESQoQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967987"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65967987/Genetics_of_Sirenomelia_the_Mermaid_Syndrome"><img alt="Research paper thumbnail of Genetics of Sirenomelia, the Mermaid Syndrome" class="work-thumbnail" src="https://attachments.academia-assets.com/77339290/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65967987/Genetics_of_Sirenomelia_the_Mermaid_Syndrome">Genetics of Sirenomelia, the Mermaid Syndrome</a></div><div class="wp-workCard_item"><span>Congenital Anomalies in Newborn Infants - Clinical and Etiopathological Perspectives</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Sirenomelia (SML) is a rare, almost universally fatal congenital malformation presenting pathogno...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Sirenomelia (SML) is a rare, almost universally fatal congenital malformation presenting pathognomically with fused lower extremities and absent or malformed perineum. The classic Sirenomelia sequence includes a uniform spectrum of caudal malformations, spinal defects, and a single umbilical artery. SML is postulated to be due to a genetic predisposition, unmasked by biochemical or environmental triggers. Primary developmental defects in the formation of caudal mesoderm or embryonic caudal vessels with resultant local tissue hypoperfusion are proposed hypotheses for its pathogenesis. SML occurs sporadically in humans, presumably due to a spontaneous mutation, and is speculated to have an autosomal dominant inheritance pattern. In mutant mice, specific defects in Cyp26a1 and Bmp 7 genes are demonstrated to produce offsprings with SML. Bmp 7 is a signaling protein, which belongs to the transforming growth factor-β (TGF β) superfamily. Tsg 1, a Bmp and chordin-binding protein, function...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9615c368afe5edd7d1eaf563c7625a4c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":77339290,"asset_id":65967987,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/77339290/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967987"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967987"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967987; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967986"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/65967986/Immediate_Postnatal_Microbial_Colonization_in_Sick_Term_Neonates_Admitted_to_NICU_Prevalence_Microbiota_and_Associated_Characteristics"><img alt="Research paper thumbnail of Immediate Postnatal Microbial Colonization in Sick Term Neonates Admitted to NICU: Prevalence, Microbiota, and Associated Characteristics" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/65967986/Immediate_Postnatal_Microbial_Colonization_in_Sick_Term_Neonates_Admitted_to_NICU_Prevalence_Microbiota_and_Associated_Characteristics">Immediate Postnatal Microbial Colonization in Sick Term Neonates Admitted to NICU: Prevalence, Microbiota, and Associated Characteristics</a></div><div class="wp-workCard_item"><span>American Journal of Perinatology</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objective The immediate postnatal rectal (RC) and nasopharyngeal colonization (NPC), their preval...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objective The immediate postnatal rectal (RC) and nasopharyngeal colonization (NPC), their prevalence, taxa, and associated characteristics were investigated in sick term infants admitted to the neonatal intensive care unit. Study Design In a retrospective cohort single center study, nasopharyngeal (NPCx) and rectal (RCx) microbial cultures were obtained within 20 minutes of birth in mild-to- moderate sick term infants. Associations between the colonization and maternal–neonatal variables, including early neonatal course, were analyzed via logistic regression analysis. Results A total of 154 term infants were admitted for respiratory distress, hypoglycemia, maternal chorioamnionitis (CHO), and suspected neonatal sepsis; out of which, 80 (52%) were NPCx-positive (+) infants. The duration of rupture of membrane (ROM) was higher (15.5 ± 10.0 vs. 11.3 ± 11.0 hours, p = 0.02), while the respiratory support requirement (16.3 vs. 29.7%, p = 0.04) and occurrence of maternal group B Streptoc...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967986"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967986"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967986; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967986]").text(description); $(".js-view-count[data-work-id=65967986]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65967986; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65967986']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=65967986]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65967986,"title":"Immediate Postnatal Microbial Colonization in Sick Term Neonates Admitted to NICU: Prevalence, Microbiota, and Associated Characteristics","internal_url":"https://www.academia.edu/65967986/Immediate_Postnatal_Microbial_Colonization_in_Sick_Term_Neonates_Admitted_to_NICU_Prevalence_Microbiota_and_Associated_Characteristics","owner_id":46689468,"coauthors_can_edit":true,"owner":{"id":46689468,"first_name":"rita","middle_initials":null,"last_name":"verma","page_name":"ritaverma5","domain_name":"independent","created_at":"2016-04-08T22:33:43.366-07:00","display_name":"rita verma","url":"https://independent.academia.edu/ritaverma5"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967985"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65967985/Placental_Histopathology_in_Late_Preterm_infants_Clinical_Implications"><img alt="Research paper thumbnail of Placental Histopathology in Late Preterm infants: Clinical Implications" class="work-thumbnail" src="https://attachments.academia-assets.com/77339188/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65967985/Placental_Histopathology_in_Late_Preterm_infants_Clinical_Implications">Placental Histopathology in Late Preterm infants: Clinical Implications</a></div><div class="wp-workCard_item"><span>Korean Journal of Pediatrics</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: The etiopathogenesis of late preterm (LPT) birth is undetermined. Placental histopath...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: The etiopathogenesis of late preterm (LPT) birth is undetermined. Placental histopathology, which reflects an adverse intrauterine environment and is reportedly associated with preterm labor and neonatal morbidities, has not been studied in LPT infants.Purpose: We investigated placental pathological lesion as markers of an adverse intrauterine environment during LPT labor.Methods: This retrospective case-control study compared placental histopathological and clinical variables between LPT and term neonates. Placental variables included chorioamnionitis, funisitis, hemorrhage, abruption, infarction, calcification, and syncytial knots. Maternal variables included age, substance abuse, pregnancyassociated diabetes mellitus and hypertension, duration of rupture of membrane, antibiotic use, and magnesium sulfate, whereas, those of neonates included gestational age, birth weight, race, sex, and Apgar scores. Standard statistical proedures were applied to analyze the data.Resul...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7731f7373a10e339bcdf49b433851eee" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":77339188,"asset_id":65967985,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/77339188/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967985"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967985"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967985; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65967984"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/65967984/Complications_associated_with_the_current_sequential_pharmacological_management_of_early_postnatal_hypotension_in_extremely_premature_infants"><img alt="Research paper thumbnail of Complications associated with the current sequential pharmacological management of early postnatal hypotension in extremely premature infants" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/65967984/Complications_associated_with_the_current_sequential_pharmacological_management_of_early_postnatal_hypotension_in_extremely_premature_infants">Complications associated with the current sequential pharmacological management of early postnatal hypotension in extremely premature infants</a></div><div class="wp-workCard_item"><span>Baylor University Medical Center Proceedings</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Abstract Early postnatal hypotension in premature infants is treated with escalating doses of vas...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Abstract Early postnatal hypotension in premature infants is treated with escalating doses of vasopressor-inotropes (VI), followed by hydrocortisone if VI therapy fails. The adverse effects of this standard clinical practice have not been well reported. In a retrospective case-control study, we compared the complications associated with VI and hydrocortisone (HCVI) treatments in extremely low-birth-weight infants (≤1000 g) with contemporaneous normotensive medication-naïve controls via standard univariate and multivariate analyses. Birth weight, gestational age, and receipt of antenatal steroids did not differ between VI (n = 74) and control (n = 124) groups, while the occurrence of gestational diabetes mellitus and risks for patent ductus arteriosus, intraventricular-periventricular hemorrhage, spontaneous intestinal perforation, ventriculomegaly, and bronchopulmonary dsyplasia were higher in VI. Infants in the HCVI group (n = 69) had lower birth weight, gestational age, and receipt of antenatal steroids and higher risks for intraventricular-periventricular hemorrhage, bronchopulmonary dysplasia, air leaks, and patent ductus arteriosus than controls. Whereas the occurrences of spontaneous intestinal perforation, ventriculomegaly, and maternal diabetes mellitus did not differ, that of maternal hypertension trended to be lower in HCVI recipients (P = 0.06). In conclusion, hypotensive extremely low-birth-weight infants treated with VI or with HCVI are susceptible to intraventricular-periventricular hemorrhage, bronchopulmonary dysplasia, and patent ductus arteriosus. Furthermore, those who receive inotropes are at risk for spontaneous intestinal perforation and ventriculomegaly. Maternal diabetes mellitus increases the occurrence of hypotension, which responds to VI. Maternal hypertension does not contribute to VI responsive and tends to decrease the occurrence of VI-refractory hypotension.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65967984"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65967984"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65967984; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65967984]").text(description); 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