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href="/w/index.php?title=Spezial:Letzte_%C3%84nderungen&feed=atom"> <link rel="dns-prefetch" href="//meta.wikimedia.org" /> <link rel="dns-prefetch" href="login.wikimedia.org"> </head> <body class="skin-vector-legacy mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject mw-editable page-Mabinlin_2 rootpage-Mabinlin_2 skin-vector action-view"><div id="mw-page-base" class="noprint"></div> <div id="mw-head-base" class="noprint"></div> <div id="content" class="mw-body" role="main"> <a id="top"></a> <div id="siteNotice"></div> <div class="mw-indicators"> </div> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Mabinlin 2</span></h1> <div id="bodyContent" class="vector-body"> <div id="siteSub" class="noprint">aus Wikipedia, der freien Enzyklopädie</div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="contentSub2"></div> <div id="jump-to-nav"></div> <a class="mw-jump-link" href="#mw-head">Zur Navigation springen</a> <a class="mw-jump-link" href="#searchInput">Zur Suche springen</a> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="de" dir="ltr"><table class="wikitable hintergrundfarbe-basis infobox float-right" id="Vorlage_Infobox_Protein" style="font-size:90%; margin-top:0; width:350px;" summary="Infobox Protein"> <tbody><tr> <th colspan="3" style="background:#90EE90; color:#202122;">Mabinlin 2 </th></tr> <tr style="text-align:center;"> <td colspan="3"><span typeof="mw:File"><a href="/wiki/Datei:Mabinlin_II_2DS2.png" class="mw-file-description" title="Mabinlin 2"><img alt="Mabinlin 2" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Mabinlin_II_2DS2.png/250px-Mabinlin_II_2DS2.png" decoding="async" width="250" height="186" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Mabinlin_II_2DS2.png/375px-Mabinlin_II_2DS2.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Mabinlin_II_2DS2.png/500px-Mabinlin_II_2DS2.png 2x" data-file-width="1000" data-file-height="742" /></a></span> </td></tr> <tr> <td colspan="3" class="hintergrundfarbe1" style="text-align:center; font-size:smaller; font-weight:bold;">nach <a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a> <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2DS2">2DS2</a> </td></tr> <tr> <td>Andere Namen </td> <td colspan="2"> <p>Mabinlin II, MAB II, Sweet protein mabinlin-2 </p> </td></tr> <tr> <td><a href="/wiki/Pr%C3%A4kursor-Proteine" title="Präkursor-Proteine">Präkursor</a> </td> <td colspan="2" style="text-align:center;">155 <a href="/wiki/Aminos%C3%A4uren" title="Aminosäuren">Aminosäuren</a>, 18.089 <a href="/wiki/Atomare_Masseneinheit" title="Atomare Masseneinheit">Da</a> </td></tr> <tr> <th colspan="3" style="background:#90EE90; color:#202122;">Bezeichner </th></tr> <tr> <td>Externe IDs </td> <td colspan="2" class="plainlinks"> <ul><li><a href="/wiki/UniProt" title="UniProt">UniProt</a> <a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprotkb/P30233">P30233</a></li></ul> </td></tr> </tbody></table><p><span class="editoronly" style="display:none;"></span> </p><p><b>Mabinlin 2</b> ist ein <a href="/wiki/Protein" title="Protein">Protein</a> aus der chinesischen Pflanze <i><a href="/wiki/Capparis_masaikai" title="Capparis masaikai">Capparis masaikai</a></i> (Mabinlang), das einen <a href="/wiki/Gustatorische_Wahrnehmung" title="Gustatorische Wahrnehmung">Süßgeschmack</a> auf der Zunge von Menschen erzeugt. </p> <div class="mw-heading mw-heading2"><h2 id="Eigenschaften">Eigenschaften</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mabinlin_2&veaction=edit&section=1" title="Abschnitt bearbeiten: Eigenschaften" class="mw-editsection-visualeditor"><span>Bearbeiten</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Mabinlin_2&action=edit&section=1" title="Quellcode des Abschnitts bearbeiten: Eigenschaften"><span>Quelltext bearbeiten</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Mabinlin 2 gehört, wie auch seine <a href="/wiki/Homologie_(Genetik)" title="Homologie (Genetik)">Homologe</a> <a href="/wiki/Mabinlin_1" title="Mabinlin 1">Mabinlin 1</a>, <a href="/wiki/Mabinlin_3" title="Mabinlin 3">Mabinlin 3</a> und <a href="/wiki/Mabinlin_4" title="Mabinlin 4">Mabinlin 4</a>, zu den 2S-<a href="/wiki/Speicherprotein" class="mw-redirect" title="Speicherprotein">Speicherproteinen</a> von Mabinlang.<sup id="cite_ref-uniprot-30233_1-0" class="reference"><a href="#cite_note-uniprot-30233-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Es besitzt vier <a href="/wiki/Disulfidbr%C3%BCcke" title="Disulfidbrücke">Disulfidbrücken</a> und ist <a href="/wiki/Thermostabil" class="mw-redirect" title="Thermostabil">thermostabil</a>.<sup id="cite_ref-uniprot-30233_1-1" class="reference"><a href="#cite_note-uniprot-30233-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Unter den Mabinlinen besitzt Mabinlin 2 die höchste Thermostabilität.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Nach der <a href="/wiki/Translation_(Biologie)" title="Translation (Biologie)">Translation</a> wird es <a href="/wiki/Posttranslationale_Modifikation" title="Posttranslationale Modifikation">posttranslational</a> durch <a href="/wiki/Proteolyse" title="Proteolyse">Proteolyse</a> in zwei Teile gespalten, Kette A (Position 36–68) und Kette B (Position 83–154).<sup id="cite_ref-uniprot-30233_1-2" class="reference"><a href="#cite_note-uniprot-30233-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> An den Positionen 36 und 83 befindet sich eine <a href="/w/index.php?title=Pyrrolidoncarbons%C3%A4ure&action=edit&redlink=1" class="new" title="Pyrrolidoncarbonsäure (Seite nicht vorhanden)">Pyrrolidoncarbonsäure</a>.<sup id="cite_ref-uniprot-30233_1-3" class="reference"><a href="#cite_note-uniprot-30233-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p><b>Homologe von Mabinlin 2</b> </p> <blockquote> <p><i><b>Kette A</b></i><br /> <b>M-1:</b> <span style="font-family:monospace;">EPLCRRQFQQ HQHLRACQRY IRRRAQRGGL VD</span><br /> <b>M-2:</b> <span style="font-family:monospace;">QLWRCQRQFL QHQRLRACQR FIHRRAQFGG QPD </span><br /> <b>M-3:</b> <span style="font-family:monospace;">EPLCRRQFQQ HQHLRACQRY LRRRAQRGGL AD </span><br /> <b>M-4:</b> <span style="font-family:monospace;">EPLCRRQFQQ HQHLRACQRY LRRRAQRG </span><br /><br /> <i><b>Kette B</b></i><br /> <b>M-1:</b> <span style="font-family:monospace;">EQRGPALRLC CNQLRQVNKP CVCPVLRQAA HQQLYQGQIE GPRQVRQLFR AARNLPNICK IPAVGRCQFT RW</span><br /> <b>M-2:</b> <span style="font-family:monospace;">QPRRPALRQC CNQLRQVDRP CVCPVLRQAA QQVLQRQIIQ GPQQLRRLFD AARNLPNICN IPNIGACPFR AW</span><br /> <b>M-3:</b> <span style="font-family:monospace;">EQRGPALRLC CNQLRQVNKP CVCPVLRQAA HQQLYQGQIE GPRQVRRLFR AARNLPNICK IPAVGRCQFT RW</span><br /> <b>M-4:</b> <span style="font-family:monospace;">EQRGPALRLC CNQLRQVNKP CVCPVLRQAA HQQLYQGQIE GPRQVRRLFR AARNLPNICK IPAVGRCQFT RW</span><br /> Aminosäuresequenzen nach <a href="/wiki/UniProt" title="UniProt">UniProt</a>.<sup id="cite_ref-P80351_3-0" class="reference"><a href="#cite_note-P80351-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-P30233_4-0" class="reference"><a href="#cite_note-P30233-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-P80352_5-0" class="reference"><a href="#cite_note-P80352-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-P80353_6-0" class="reference"><a href="#cite_note-P80353-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> </blockquote> <div class="mw-heading mw-heading2"><h2 id="Literatur">Literatur</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mabinlin_2&veaction=edit&section=2" title="Abschnitt bearbeiten: Literatur" class="mw-editsection-visualeditor"><span>Bearbeiten</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Mabinlin_2&action=edit&section=2" title="Quellcode des Abschnitts bearbeiten: Literatur"><span>Quelltext bearbeiten</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>X. Liu, S. Maeda, Z. Hu, T. Aiuchi, K. Nakaya, Y. Kurihara: <i>Purification, complete amino acid sequence and structural characterization of the heat-stable sweet protein, mabinlin II.</i> In: <i><a href="/wiki/FEBS_Journal" title="FEBS Journal">European Journal of Biochemistry</a>.</i> Band 211, Nummer 1–2, Januar 1993, S. 281–287, <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/8425538?dopt=Abstract">PMID 8425538</a>.</li> <li>Z. Hu, M. He: <a rel="nofollow" class="external text" href="http://en.cnki.com.cn/Article_en/CJFDTOTAL-YOKE198602011.htm"><i>Studies on mabinlin, a sweet protein from the seeds of Capparis masaikai levl. I. extraction, purification and certain characteristics.</i></a> In: <i>Acta Botan. Yunnan.</i> (1983), Band 5, S. 207–212.</li> <li>S. Nirasawa, T. Nishino, M. Katahira, S. Uesugi, Z. Hu, Y. Kurihara: <i>Structures of heat-stable and unstable homologues of the sweet protein mabinlin. The difference in the heat stability is due to replacement of a single amino acid residue.</i> In: <i><a href="/wiki/FEBS_Journal" title="FEBS Journal">European Journal of Biochemistry</a>.</i> Band 223, Nummer 3, August 1994, S. 989–995, <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/8055976?dopt=Abstract">PMID 8055976</a>.</li> <li>Y. Kurihara: <i>Characteristics of antisweet substances, sweet proteins, and sweetness-inducing proteins.</i> In: <i>Critical reviews in food science and nutrition.</i> Band 32, Nummer 3, 1992, S. 231–252, <a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1080/10408399209527598">10.1080/10408399209527598</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/1418601?dopt=Abstract">PMID 1418601</a>.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Einzelnachweise">Einzelnachweise</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mabinlin_2&veaction=edit&section=3" title="Abschnitt bearbeiten: Einzelnachweise" class="mw-editsection-visualeditor"><span>Bearbeiten</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Mabinlin_2&action=edit&section=3" title="Quellcode des Abschnitts bearbeiten: Einzelnachweise"><span>Quelltext bearbeiten</span></a><span class="mw-editsection-bracket">]</span></span></div> <ol class="references"> <li id="cite_note-uniprot-30233-1"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-uniprot-30233_1-0">a</a></sup> <sup><a href="#cite_ref-uniprot-30233_1-1">b</a></sup> <sup><a href="#cite_ref-uniprot-30233_1-2">c</a></sup> <sup><a href="#cite_ref-uniprot-30233_1-3">d</a></sup></span> <span class="reference-text"><a href="/wiki/UniProt" title="UniProt">UniProt</a> <a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprotkb/P30233">Sweet protein mabinlin-2 precursor - Capparis masaikai (Mabinlang)</a>. Abgerufen am 24. Oktober 2018.</span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text">R. J. Guan, J. M. Zheng, Z. Hu, D. C. Wang: <i>Crystallization and preliminary X-ray analysis of the thermostable sweet protein mabinlin II.</i> In: <i>Acta crystallographica. Section D, Biological crystallography.</i> Band 56, Pt 7Juli 2000, S. 918–919, <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/10930844?dopt=Abstract">PMID 10930844</a>.</span> </li> <li id="cite_note-P80351-3"><span class="mw-cite-backlink"><a href="#cite_ref-P80351_3-0">↑</a></span> <span class="reference-text"><a href="/wiki/UniProt" title="UniProt">UniProt</a> <a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprotkb/P80351">P80351</a></span> </li> <li id="cite_note-P30233-4"><span class="mw-cite-backlink"><a href="#cite_ref-P30233_4-0">↑</a></span> <span class="reference-text"><a href="/wiki/UniProt" title="UniProt">UniProt</a> <a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprotkb/P30233">P30233</a></span> </li> <li id="cite_note-P80352-5"><span class="mw-cite-backlink"><a href="#cite_ref-P80352_5-0">↑</a></span> <span class="reference-text"><a href="/wiki/UniProt" title="UniProt">UniProt</a> <a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprotkb/P80352">P80352</a></span> </li> <li id="cite_note-P80353-6"><span class="mw-cite-backlink"><a href="#cite_ref-P80353_6-0">↑</a></span> <span class="reference-text"><a href="/wiki/UniProt" title="UniProt">UniProt</a> <a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprotkb/P80353">P80353</a></span> </li> </ol></div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Abgerufen von „<a dir="ltr" href="https://de.wikipedia.org/w/index.php?title=Mabinlin_2&oldid=247091682">https://de.wikipedia.org/w/index.php?title=Mabinlin_2&oldid=247091682</a>“</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Wikipedia:Kategorien" title="Wikipedia:Kategorien">Kategorien</a>: <ul><li><a href="/wiki/Kategorie:Protein" title="Kategorie:Protein">Protein</a></li><li><a href="/wiki/Kategorie:S%C3%BC%C3%9Fstoff" title="Kategorie:Süßstoff">Süßstoff</a></li></ul></div></div> </div> </div> <div id="mw-navigation"> <h2>Navigationsmenü</h2> <div id="mw-head"> <nav id="p-personal" class="mw-portlet mw-portlet-personal vector-user-menu-legacy vector-menu" aria-labelledby="p-personal-label" > <h3 id="p-personal-label" class="vector-menu-heading " > <span class="vector-menu-heading-label">Meine Werkzeuge</span> </h3> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anonuserpage" class="mw-list-item"><span title="Benutzerseite der IP-Adresse, von der aus du Änderungen durchführst">Nicht angemeldet</span></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Spezial:Meine_Diskussionsseite" title="Diskussion über Änderungen von dieser IP-Adresse [n]" accesskey="n"><span>Diskussionsseite</span></a></li><li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Spezial:Meine_Beitr%C3%A4ge" title="Eine Liste der Bearbeitungen, die von dieser IP-Adresse gemacht wurden [y]" accesskey="y"><span>Beiträge</span></a></li><li id="pt-createaccount" class="mw-list-item"><a href="/w/index.php?title=Spezial:Benutzerkonto_anlegen&returnto=Mabinlin+2" title="Wir ermutigen dich dazu, ein Benutzerkonto zu erstellen und dich anzumelden. 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