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searchaux" style="display:none">Enzyme</div> <table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">RPS6KB2</th></tr><tr><td colspan="4" style="text-align:center"></td></tr><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Identifiers</th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/10437">RPS6KB2</a></span>, KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb, ribosomal protein S6 kinase B2, S6KB, S6KI(2), S6Kbeta</td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">External IDs</th><td colspan="3" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/608939">608939</a>; <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:1927343">1927343</a>; <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=68374">68374</a>; <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=RPS6KB2">RPS6KB2</a>; <a href="/wiki/Orthologous_MAtrix" title="Orthologous MAtrix">OMA</a>:<a rel="nofollow" class="external text" href="https://omabrowser.org/oma/vps/ENSG00000175634">RPS6KB2 - orthologs</a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span typeof="mw:File"><a href="/wiki/File:Ideogram_human_chromosome_11.svg" class="mw-file-description" title="Chromosome 11 (human)"><img alt="Chromosome 11 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/300px-Ideogram_human_chromosome_11.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/450px-Ideogram_human_chromosome_11.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/600px-Ideogram_human_chromosome_11.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a href="/wiki/Chromosome_11_(human)" class="mw-redirect" title="Chromosome 11 (human)">Chromosome 11 (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Human_chromosome_11_ideogram.svg" class="mw-file-description" title="Chromosome 11 (human)"><img alt="Chromosome 11 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/300px-Human_chromosome_11_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/450px-Human_chromosome_11_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/43/Human_chromosome_11_ideogram.svg/600px-Human_chromosome_11_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: 141.42408373601px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for RPS6KB2"><img alt="Genomic location for RPS6KB2" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 147.4px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for RPS6KB2"><img alt="Genomic location for RPS6KB2" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">11q13.2</span></td><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Start</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">67,428,460 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">End</th><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks">67,435,401 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Gene_expression" title="Gene expression">RNA expression</a> pattern</th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a rel="nofollow" class="external text" href="https://www.bgee.org/">Bgee</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th><b><a href="/wiki/Human_genome" title="Human genome">Human</a></b></th><th><b><a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a> (ortholog)</b></th></tr><tr><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000175634">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">skin of leg</li><br /><li style="line-height: 137%;">skin of abdomen</li><br /><li style="line-height: 137%;">granulocyte</li><br /><li style="line-height: 137%;">body of stomach</li><br /><li style="line-height: 137%;">apex of heart</li><br /><li style="line-height: 137%;">right lobe of liver</li><br /><li style="line-height: 137%;">right hemisphere of cerebellum</li><br /><li style="line-height: 137%;">anterior pituitary</li><br /><li style="line-height: 137%;">muscle of thigh</li><br /><li style="line-height: 137%;">mucosa of transverse colon</li></ul></div></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px">n/a</ul></div></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000175634">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span typeof="mw:File"><a href="/wiki/File:PBB_GE_RPS6KB2_203777_s_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/3/33/PBB_GE_RPS6KB2_203777_s_at_fs.png/250px-PBB_GE_RPS6KB2_203777_s_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/33/PBB_GE_RPS6KB2_203777_s_at_fs.png/375px-PBB_GE_RPS6KB2_203777_s_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/33/PBB_GE_RPS6KB2_203777_s_at_fs.png/500px-PBB_GE_RPS6KB2_203777_s_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/6199/">More reference expression data</a></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Gene_ontology" class="mw-redirect" title="Gene ontology">Gene ontology</a></th></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Molecular function</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016740">transferase activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0004672">protein kinase activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0000166">nucleotide binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042277">peptide binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016301">kinase activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0004674">protein serine/threonine kinase activity</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005524">ATP binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0004711">ribosomal protein S6 kinase activity</a></li></ul> </div></td></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Cellular component</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005737">cytoplasm</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005654">nucleoplasm</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005634">nucleus</a></li></ul> </div></td></tr><tr><td style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit;font-weight:bold">Biological process</td><td style="background-color:light-dark(#eee, #27292d) !important;color:inherit"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0035556">intracellular signal transduction</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006412">protein biosynthesis</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016310">phosphorylation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006468">protein phosphorylation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045948">positive regulation of translational initiation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007165">signal transduction</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043491">protein kinase B signaling</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031929">TOR signaling</a></li></ul> </div></td></tr><tr><td colspan="4" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center">Sources:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table class="collapsible" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:light-dark(#ddd, #404244) !important;color:inherit"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=6199&rn=1">6199</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=58988&rn=1">58988</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000175634;db=core">ENSG00000175634</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000024830;db=core">ENSMUSG00000024830</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q9UBS0">Q9UBS0</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q9Z1M4">Q9Z1M4</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">RefSeq (mRNA)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001007071">NM_001007071</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_003952">NM_003952</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_021485">NM_021485</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">RefSeq (protein)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_003943">NP_003943</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_067460.1">NP_067460.1</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit">Location (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chr11:67428460-67435401">Chr 11: 67.43 – 67.44 Mb</a></span></td><td><span class="plainlinks">n/a</span></td></tr><tr><th scope="row" style="background-color:light-dark(#c3fdb8, #003500) !important;color:inherit"><a href="/wiki/PubMed" title="PubMed">PubMed</a> search</th><td><span class="plainlinks"><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a></td></tr><tr><td colspan="4" style="text-align:center;background-color:light-dark(#eee, #27292d) !important;color:inherit"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center"><a href="https://www.wikidata.org/wiki/Q18031290" class="extiw" title="d:Q18031290">View/Edit Human</a></td><td colspan="2" style="background-color:light-dark(#eee, #27292d) !important;color:inherit;text-align:center"><a href="https://www.wikidata.org/wiki/Q18258921" class="extiw" title="d:Q18258921">View/Edit Mouse</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>Ribosomal protein S6 kinase beta-2</b> is an <a href="/wiki/Enzyme" title="Enzyme">enzyme</a> that in humans is encoded by the <i>RPS6KB2</i> <a href="/wiki/Gene" title="Gene">gene</a>.<sup id="cite_ref-pmid9878560_4-0" class="reference"><a href="#cite_note-pmid9878560-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9804755_5-0" class="reference"><a href="#cite_note-pmid9804755-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-entrez_6-0" class="reference"><a href="#cite_note-entrez-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine <a href="/wiki/Kinase" title="Kinase">kinases</a>. This kinase contains two nonidentical kinase catalytic domains and <a href="/wiki/Phosphorylation" title="Phosphorylation">phosphorylates</a> the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.<sup id="cite_ref-entrez_6-1" class="reference"><a href="#cite_note-entrez-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=RPS6KB2&action=edit&section=1" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000175634">GRCh38: Ensembl release 89: ENSG00000175634</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=6199">"Human PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Human+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D6199&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARPS6KB2" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=58988">"Mouse PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Mouse+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D58988&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARPS6KB2" class="Z3988"></span></span> </li> <li id="cite_note-pmid9878560-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9878560_4-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFSaitohten_DijkeMiyazonoIchijo1999" class="citation journal cs1">Saitoh M, ten Dijke P, Miyazono K, Ichijo H (Jan 1999). "Cloning and characterization of p70(S6K beta) defines a novel family of p70 S6 kinases". <i>Biochem Biophys Res Commun</i>. <b>253</b> (2): <span class="nowrap">470–</span>476. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1006%2Fbbrc.1998.9784">10.1006/bbrc.1998.9784</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9878560">9878560</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Biochem+Biophys+Res+Commun&rft.atitle=Cloning+and+characterization+of+p70%28S6K+beta%29+defines+a+novel+family+of+p70+S6+kinases&rft.volume=253&rft.issue=2&rft.pages=%3Cspan+class%3D%22nowrap%22%3E470-%3C%2Fspan%3E476&rft.date=1999-01&rft_id=info%3Adoi%2F10.1006%2Fbbrc.1998.9784&rft_id=info%3Apmid%2F9878560&rft.aulast=Saitoh&rft.aufirst=M&rft.au=ten+Dijke%2C+P&rft.au=Miyazono%2C+K&rft.au=Ichijo%2C+H&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARPS6KB2" class="Z3988"></span></span> </li> <li id="cite_note-pmid9804755-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9804755_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFGoutMinamiHaraTsujishita1998" class="citation journal cs1">Gout I, Minami T, Hara K, Tsujishita Y, Filonenko V, Waterfield MD, Yonezawa K (Dec 1998). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.273.46.30061">"Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region"</a>. <i>J Biol Chem</i>. <b>273</b> (46): <span class="nowrap">30061–</span>30064. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.273.46.30061">10.1074/jbc.273.46.30061</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9804755">9804755</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J+Biol+Chem&rft.atitle=Molecular+cloning+and+characterization+of+a+novel+p70+S6+kinase%2C+p70+S6+kinase+beta+containing+a+proline-rich+region&rft.volume=273&rft.issue=46&rft.pages=%3Cspan+class%3D%22nowrap%22%3E30061-%3C%2Fspan%3E30064&rft.date=1998-12&rft_id=info%3Adoi%2F10.1074%2Fjbc.273.46.30061&rft_id=info%3Apmid%2F9804755&rft.aulast=Gout&rft.aufirst=I&rft.au=Minami%2C+T&rft.au=Hara%2C+K&rft.au=Tsujishita%2C+Y&rft.au=Filonenko%2C+V&rft.au=Waterfield%2C+MD&rft.au=Yonezawa%2C+K&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.273.46.30061&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARPS6KB2" class="Z3988"></span></span> </li> <li id="cite_note-entrez-6"><span class="mw-cite-backlink">^ <a href="#cite_ref-entrez_6-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-entrez_6-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6199">"Entrez Gene: RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Entrez+Gene%3A+RPS6KB2+ribosomal+protein+S6+kinase%2C+70kDa%2C+polypeptide+2&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D6199&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARPS6KB2" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=RPS6KB2&action=edit&section=2" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-width" style="column-width: 30em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFLee-Fruman_KKKuo_CJLippincott_JTerada1999" class="citation journal cs1">Lee-Fruman KK, Kuo CJ, Lippincott J, et al. (1999). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fsj.onc.1202894">"Characterization of S6K2, a novel kinase homologous to S6K1"</a>. <i>Oncogene</i>. <b>18</b> (36): <span class="nowrap">5108–</span>5114. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fsj.onc.1202894">10.1038/sj.onc.1202894</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10490847">10490847</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Oncogene&rft.atitle=Characterization+of+S6K2%2C+a+novel+kinase+homologous+to+S6K1&rft.volume=18&rft.issue=36&rft.pages=%3Cspan+class%3D%22nowrap%22%3E5108-%3C%2Fspan%3E5114&rft.date=1999&rft_id=info%3Adoi%2F10.1038%2Fsj.onc.1202894&rft_id=info%3Apmid%2F10490847&rft.au=Lee-Fruman+KK&rft.au=Kuo+CJ&rft.au=Lippincott+J&rft.au=Terada%2C+Naohiro&rft.au=Blenis%2C+John&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252Fsj.onc.1202894&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARPS6KB2" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFKoh_HJee_KLee_BKim1999" class="citation journal cs1">Koh H, Jee K, Lee B, et al. (1999). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fsj.onc.1202895">"Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt"</a>. <i>Oncogene</i>. <b>18</b> (36): <span class="nowrap">5115–</span>5119. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fsj.onc.1202895">10.1038/sj.onc.1202895</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10490848">10490848</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Oncogene&rft.atitle=Cloning+and+characterization+of+a+nuclear+S6+kinase%2C+S6+kinase-related+kinase+%28SRK%29%3B+a+novel+nuclear+target+of+Akt&rft.volume=18&rft.issue=36&rft.pages=%3Cspan+class%3D%22nowrap%22%3E5115-%3C%2Fspan%3E5119&rft.date=1999&rft_id=info%3Adoi%2F10.1038%2Fsj.onc.1202895&rft_id=info%3Apmid%2F10490848&rft.au=Koh+H&rft.au=Jee+K&rft.au=Lee+B&rft.au=Kim%2C+Jeonghoon&rft.au=Kim%2C+Dohoon&rft.au=Yun%2C+Young-Ha&rft.au=Kim%2C+Jung+Woo&rft.au=Choi%2C+Heung-Sik&rft.au=Chung%2C+Jongkyeong&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252Fsj.onc.1202895&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARPS6KB2" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMartin_KASchalm_SSRichardson_CRomanelli2001" class="citation journal cs1">Martin KA, Schalm SS, Richardson C, et al. 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Chem</i>. <b>276</b> (11): <span class="nowrap">7884–</span>7891. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M006969200">10.1074/jbc.M006969200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11108711">11108711</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=Regulation+of+ribosomal+S6+kinase+2+by+effectors+of+the+phosphoinositide+3-kinase+pathway&rft.volume=276&rft.issue=11&rft.pages=%3Cspan+class%3D%22nowrap%22%3E7884-%3C%2Fspan%3E7891&rft.date=2001&rft_id=info%3Adoi%2F10.1074%2Fjbc.M006969200&rft_id=info%3Apmid%2F11108711&rft.au=Martin+KA&rft.au=Schalm+SS&rft.au=Richardson+C&rft.au=Romanelli%2C+A&rft.au=Keon%2C+KL&rft.au=Blenis%2C+J&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.M006969200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARPS6KB2" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMartin_KASchalm_SSRomanelli_AKeon2001" class="citation journal cs1">Martin KA, Schalm SS, Romanelli A, et al. (2001). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M009972200">"Ribosomal S6 kinase 2 inhibition by a potent C-terminal repressor domain is relieved by mitogen-activated protein-extracellular signal-regulated kinase kinase-regulated phosphorylation"</a>. <i>J. Biol. 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protein kinase">Serine/threonine-specific protein kinases</a> (<a href="/wiki/Enzyme_Commission_number" title="Enzyme Commission number">EC</a> 2.7.11-12)</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Serine/threonine-specific_protein_kinases_(EC_2.7.11.1-EC_2.7.11.20)102" style="font-size:114%;margin:0 4em"><a href="/wiki/Serine/threonine-specific_protein_kinase" title="Serine/threonine-specific protein kinase">Serine/threonine-specific protein kinases</a> (EC 2.7.11.1-EC 2.7.11.20)</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Non-specific_serine/threonine_protein_kinase" class="mw-redirect" title="Non-specific serine/threonine protein kinase">Non-specific serine/threonine protein kinases</a> (EC 2.7.11.1)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/LATS1" title="LATS1">LATS1</a></li> <li><a href="/wiki/LATS2" title="LATS2">LATS2</a></li> <li><a href="/wiki/MAST1" title="MAST1">MAST1</a></li> <li><a href="/wiki/MAST2" title="MAST2">MAST2</a></li> <li><a href="/wiki/STK38" title="STK38">STK38</a></li> <li><a href="/wiki/STK38L" title="STK38L">STK38L</a></li> <li><a href="/wiki/CIT_(gene)" class="mw-redirect" title="CIT (gene)">CIT</a></li> <li><a href="/wiki/ROCK1" title="ROCK1">ROCK1</a></li> <li><a href="/wiki/SGK" title="SGK">SGK</a></li> <li><a href="/wiki/SGK2" title="SGK2">SGK2</a></li> <li><a href="/wiki/SGK3" title="SGK3">SGK3</a></li> <li><a href="/wiki/AKT" class="mw-redirect" title="AKT">Protein kinase B</a> <ul><li><a href="/wiki/AKT1" title="AKT1">AKT1</a></li> <li><a href="/wiki/AKT2" title="AKT2">AKT2</a></li> <li><a href="/wiki/AKT3" title="AKT3">AKT3</a></li></ul></li> <li><a href="/wiki/Ataxia_telangiectasia_mutated" class="mw-redirect" title="Ataxia telangiectasia mutated">Ataxia telangiectasia mutated</a></li> <li><a href="/wiki/MTOR" title="MTOR">mTOR</a></li> <li><a href="/wiki/EIF-2_kinase" title="EIF-2 kinase">EIF-2 kinases</a> <ul><li><a href="/wiki/Protein_kinase_R" title="Protein kinase R">PKR</a></li> <li><a href="/wiki/EIF2AK1" title="EIF2AK1">HRI</a></li> <li><a href="/wiki/EIF2AK3" title="EIF2AK3">EIF2AK3</a></li> <li><a href="/wiki/EIF2AK4" title="EIF2AK4">EIF2AK4</a></li></ul></li> <li><a href="/wiki/Wee1" title="Wee1">Wee1</a> <ul><li><a href="/wiki/Wee1-like_protein_kinase" title="Wee1-like protein kinase">WEE1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Pyruvate_dehydrogenase_kinase" title="Pyruvate dehydrogenase kinase">Pyruvate dehydrogenase kinase</a> (EC 2.7.11.2)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Pyruvate_dehydrogenase_lipoamide_kinase_isozyme_1" title="Pyruvate dehydrogenase lipoamide kinase isozyme 1">PDK1</a></li> <li><a href="/wiki/PDK2" title="PDK2">PDK2</a></li> <li><a href="/wiki/PDK3" title="PDK3">PDK3</a></li> <li><a href="/wiki/PDK4" title="PDK4">PDK4</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Dephospho-(reductase_kinase)_kinase" title="Dephospho-(reductase kinase) kinase">Dephospho-(reductase kinase) kinase</a> (EC 2.7.11.3)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/AMP-activated_protein_kinase" title="AMP-activated protein kinase">AMP-activated protein kinase</a> α <ul><li><a href="/wiki/Protein_kinase,_AMP-activated,_alpha_1" title="Protein kinase, AMP-activated, alpha 1">PRKAA1</a></li> <li><a href="/wiki/PRKAA2" title="PRKAA2">PRKAA2</a></li></ul></li> <li>β <ul><li><a href="/wiki/PRKAB1" title="PRKAB1">PRKAB1</a></li> <li><a href="/wiki/PRKAB2" title="PRKAB2">PRKAB2</a></li></ul></li> <li>γ <ul><li><a href="/wiki/PRKAG1" title="PRKAG1">PRKAG1</a></li> <li><a href="/wiki/PRKAG2" title="PRKAG2">PRKAG2</a></li> <li><a href="/wiki/PRKAG3" title="PRKAG3">PRKAG3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/3-methyl-2-oxobutanoate_dehydrogenase_(acetyl-transferring)_kinase" title="3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase">3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase</a> (EC 2.7.11.4)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/BCKDK" title="BCKDK">BCKDK</a></li> <li><a href="/wiki/BCKDHA" title="BCKDHA">BCKDHA</a></li> <li><a href="/wiki/BCKDHB" title="BCKDHB">BCKDHB</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/(isocitrate_dehydrogenase_(NADP%2B))_kinase" class="mw-redirect" title="(isocitrate dehydrogenase (NADP+)) kinase">(isocitrate dehydrogenase (NADP+)) kinase</a> (EC 2.7.11.5)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/IDH2" title="IDH2">IDH2</a></li> <li><a href="/wiki/IDH3A" title="IDH3A">IDH3A</a></li> <li><a href="/wiki/IDH3B" title="IDH3B">IDH3B</a></li> <li><a href="/wiki/IDH3G" title="IDH3G">IDH3G</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/(tyrosine_3-monooxygenase)_kinase" title="(tyrosine 3-monooxygenase) kinase">(tyrosine 3-monooxygenase) kinase</a> (EC 2.7.11.6)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/STK4" title="STK4">STK4</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Myosin-heavy-chain_kinase" title="Myosin-heavy-chain kinase">Myosin-heavy-chain kinase</a> (EC 2.7.11.7)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aurora_kinase" title="Aurora kinase">Aurora kinase</a> <ul><li><a href="/wiki/Aurora_A_kinase" class="mw-redirect" title="Aurora A kinase">Aurora A kinase</a></li> <li><a href="/wiki/Aurora_B_kinase" class="mw-redirect" title="Aurora B kinase">Aurora B kinase</a></li> <li><a href="/wiki/Aurora_C_kinase" class="mw-redirect" title="Aurora C kinase">Aurora C kinase</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fas-activated_serine/threonine_kinase" title="Fas-activated serine/threonine kinase">Fas-activated serine/threonine kinase</a> (EC 2.7.11.8)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/FASTK" title="FASTK">FASTK</a></li> <li><a href="/wiki/STK10" title="STK10">STK10</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Goodpasture-antigen-binding_protein_kinase" title="Goodpasture-antigen-binding protein kinase">Goodpasture-antigen-binding protein kinase</a> (EC 2.7.11.9)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>-</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/I%CE%BAB_kinase" title="IκB kinase">IκB kinase</a> (EC 2.7.11.10)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CHUK" title="CHUK">CHUK</a></li> <li><a href="/wiki/IKK2" title="IKK2">IKK2</a></li> <li><a href="/wiki/TANK-binding_kinase_1" title="TANK-binding kinase 1">TBK1</a></li> <li><a href="/wiki/IKBKE" title="IKBKE">IKBKE</a></li> <li><a href="/wiki/IKBKG" title="IKBKG">IKBKG</a></li> <li><a href="/wiki/IKBKAP" title="IKBKAP">IKBKAP</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Protein_kinase_A" title="Protein kinase A">cAMP-dependent protein kinase</a> (EC 2.7.11.11)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Protein_kinase_A" title="Protein kinase A">Protein kinase A</a></li> <li><a href="/wiki/PRKACG" title="PRKACG">PRKACG</a></li> <li><a href="/wiki/PRKACB" title="PRKACB">PRKACB</a></li> <li><a href="/wiki/PRKACA" title="PRKACA">PRKACA</a></li> <li><a href="/wiki/PRKY" title="PRKY">PRKY</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/CGMP-dependent_protein_kinase" title="CGMP-dependent protein kinase">cGMP-dependent protein kinase</a> (EC 2.7.11.12)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CGMP-dependent_protein_kinase" title="CGMP-dependent protein kinase">Protein kinase G</a></li> <li><a href="/wiki/PRKG1" title="PRKG1">PRKG1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Protein_kinase_C" title="Protein kinase C">Protein kinase C</a> (EC 2.7.11.13)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Protein_kinase_C" title="Protein kinase C">Protein kinase C</a></li> <li><a href="/wiki/Protein_kinase_C_zeta_type" title="Protein kinase C zeta type">Protein kinase Cζ</a></li> <li><a href="/wiki/PKC_alpha" title="PKC alpha">PKC alpha</a></li> <li><a href="/wiki/PRKCB1" title="PRKCB1">PRKCB1</a></li> <li><a href="/wiki/PRKCD" title="PRKCD">PRKCD</a></li> <li><a href="/wiki/PRKCE" title="PRKCE">PRKCE</a></li> <li><a href="/wiki/PRKCH" title="PRKCH">PRKCH</a></li> <li><a href="/wiki/PRKCG" title="PRKCG">PRKCG</a></li> <li><a href="/wiki/PRKCI" title="PRKCI">PRKCI</a></li> <li><a href="/wiki/PRKCQ" title="PRKCQ">PRKCQ</a></li> <li><a href="/wiki/Protein_kinase_N1" title="Protein kinase N1">Protein kinase N1</a></li> <li><a href="/wiki/PKN2" title="PKN2">PKN2</a></li> <li><a href="/wiki/PKN3_(gene)" title="PKN3 (gene)">PKN3</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Rhodopsin_kinase" title="Rhodopsin kinase">Rhodopsin kinase</a> (EC 2.7.11.14)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Rhodopsin_kinase" title="Rhodopsin kinase">Rhodopsin kinase</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Beta_adrenergic_receptor_kinase" class="mw-redirect" title="Beta adrenergic receptor kinase">Beta adrenergic receptor kinase</a> (EC 2.7.11.15)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Beta_adrenergic_receptor_kinase" class="mw-redirect" title="Beta adrenergic receptor kinase">Beta adrenergic receptor kinase</a></li> <li><a href="/wiki/Beta_adrenergic_receptor_kinase-2" class="mw-redirect" title="Beta adrenergic receptor kinase-2">Beta adrenergic receptor kinase-2</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/G_protein-coupled_receptor_kinase" title="G protein-coupled receptor kinase">G-protein coupled receptor kinases</a> (EC 2.7.11.16)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/GRK4" title="GRK4">GRK4</a></li> <li><a href="/wiki/GRK5" title="GRK5">GRK5</a></li> <li><a href="/wiki/GRK6" title="GRK6">GRK6</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Ca2%2B/calmodulin-dependent_protein_kinase" class="mw-redirect" title="Ca2+/calmodulin-dependent protein kinase">Ca2+/calmodulin-dependent</a> (EC 2.7.11.17)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/BRSK2" title="BRSK2">BRSK2</a></li> <li><a href="/wiki/CAMK1" title="CAMK1">CAMK1</a></li> <li><a href="/w/index.php?title=CAMK1A&action=edit&redlink=1" class="new" title="CAMK1A (page does not exist)">CAMK1A</a></li> <li><a href="/w/index.php?title=CAMK1B&action=edit&redlink=1" class="new" title="CAMK1B (page does not exist)">CAMK1B</a></li> <li><a href="/wiki/CAMK1D" title="CAMK1D">CAMK1D</a></li> <li><a href="/w/index.php?title=CAMK1G&action=edit&redlink=1" class="new" title="CAMK1G (page does not exist)">CAMK1G</a></li> <li><a href="/wiki/Ca2%2B/calmodulin-dependent_protein_kinase_II" title="Ca2+/calmodulin-dependent protein kinase II">CAMK2</a></li> <li><a href="/wiki/CAMK2A" class="mw-redirect" title="CAMK2A">CAMK2A</a></li> <li><a href="/wiki/CAMK2B" title="CAMK2B">CAMK2B</a></li> <li><a href="/wiki/CAMK2D" title="CAMK2D">CAMK2D</a></li> <li><a href="/wiki/CAMK2G" title="CAMK2G">CAMK2G</a></li> <li><a href="/wiki/CAMK4" title="CAMK4">CAMK4</a></li> <li><a href="/wiki/Myosin_light-chain_kinase" title="Myosin light-chain kinase">MLCK</a></li> <li><a href="/wiki/CASK" title="CASK">CASK</a></li> <li><a href="/wiki/CHEK1" title="CHEK1">CHEK1</a></li> <li><a href="/wiki/CHEK2" title="CHEK2">CHEK2</a></li> <li><a href="/wiki/DAPK1" title="DAPK1">DAPK1</a></li> <li><a href="/wiki/DAPK2" title="DAPK2">DAPK2</a></li> <li><a href="/wiki/DAPK3" title="DAPK3">DAPK3</a></li> <li><a href="/wiki/STK11" title="STK11">STK11</a></li> <li><a href="/wiki/MAPKAPK2" title="MAPKAPK2">MAPKAPK2</a></li> <li><a href="/wiki/MAPKAPK3" title="MAPKAPK3">MAPKAPK3</a></li> <li><a href="/wiki/MAPKAPK5" title="MAPKAPK5">MAPKAPK5</a></li> <li><a href="/wiki/MARK1" title="MARK1">MARK1</a></li> <li><a href="/wiki/MARK2" title="MARK2">MARK2</a></li> <li><a href="/wiki/MARK3" title="MARK3">MARK3</a></li> <li><a href="/wiki/MARK4" title="MARK4">MARK4</a></li> <li><a href="/wiki/MELK" title="MELK">MELK</a></li> <li><a href="/wiki/MKNK1" title="MKNK1">MKNK1</a></li> <li><a href="/wiki/MKNK2" title="MKNK2">MKNK2</a></li> <li><a href="/wiki/NUAK1" title="NUAK1">NUAK1</a></li> <li><a href="/wiki/NUAK2" title="NUAK2">NUAK2</a></li> <li><a href="/wiki/OBSCN" class="mw-redirect" title="OBSCN">OBSCN</a></li> <li><a href="/wiki/PASK" title="PASK">PASK</a></li> <li><a href="/wiki/PHKG1" title="PHKG1">PHKG1</a></li> <li><a href="/wiki/PHKG2" title="PHKG2">PHKG2</a></li> <li><a href="/wiki/PIM1" title="PIM1">PIM1</a></li> <li><a href="/wiki/PIM2_(gene)" title="PIM2 (gene)">PIM2</a></li> <li><a href="/wiki/Protein_kinase_D1" title="Protein kinase D1">PKD1</a></li> <li><a href="/wiki/PRKD2" title="PRKD2">PRKD2</a></li> <li><a href="/wiki/PRKD3" title="PRKD3">PRKD3</a></li> <li><a href="/wiki/PSKH1" title="PSKH1">PSKH1</a></li> <li><a href="/wiki/SNF1LK2" title="SNF1LK2">SNF1LK2</a></li> <li><a href="/wiki/KIAA0999" title="KIAA0999">KIAA0999</a></li> <li><a href="/wiki/STK40" title="STK40">STK40</a></li> <li><a href="/wiki/SNF1LK" class="mw-redirect" title="SNF1LK">SNF1LK</a></li> <li><a href="/wiki/SNRK" title="SNRK">SNRK</a></li> <li><a href="/wiki/SPEG" title="SPEG">SPEG</a></li> <li><a href="/wiki/TSSK2" title="TSSK2">TSSK2</a></li> <li><a href="/wiki/Kalirin" title="Kalirin">Kalirin</a></li> <li><a href="/wiki/TRIB1" title="TRIB1">TRIB1</a></li> <li><a href="/wiki/TRIB2" title="TRIB2">TRIB2</a></li> <li><a href="/wiki/TRIB3" title="TRIB3">TRIB3</a></li> <li><a href="/wiki/TRIO_(gene)" title="TRIO (gene)">TRIO</a></li> <li><a href="/wiki/Titin" title="Titin">Titin</a></li> <li><a href="/wiki/DCLK1" title="DCLK1">DCLK1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Myosin_light-chain_kinase" title="Myosin light-chain kinase">Myosin light-chain kinase</a> (EC 2.7.11.18)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/MYLK" title="MYLK">MYLK</a></li> <li><a href="/wiki/MYLK2" title="MYLK2">MYLK2</a></li> <li><a href="/wiki/MYLK3" title="MYLK3">MYLK3</a></li> <li><a href="/wiki/MYLK4" title="MYLK4">MYLK4</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Phosphorylase_kinase" title="Phosphorylase kinase">Phosphorylase kinase</a> (EC 2.7.11.19)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Phosphorylase_kinase,_alpha_1" title="Phosphorylase kinase, alpha 1">PHKA1</a></li> <li><a href="/wiki/PHKA2" title="PHKA2">PHKA2</a></li> <li><a href="/wiki/PHKB" title="PHKB">PHKB</a></li> <li><a href="/wiki/PHKG1" title="PHKG1">PHKG1</a></li> <li><a href="/wiki/PHKG2" title="PHKG2">PHKG2</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Elongation_factor_2_kinase" title="Elongation factor 2 kinase">Elongation factor 2 kinase</a> (EC 2.7.11.20)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/EEF2K" title="EEF2K">EEF2K</a></li> <li><a href="/wiki/STK19" title="STK19">STK19</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Polo_kinase" title="Polo kinase">Polo kinase</a> (EC 2.7.11.21)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/PLK1" title="PLK1">PLK1</a></li> <li><a href="/wiki/PLK2" title="PLK2">PLK2</a></li> <li><a href="/wiki/PLK3" title="PLK3">PLK3</a></li> <li><a href="/wiki/PLK4" title="PLK4">PLK4</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Serine/threonine-specific_protein_kinases_(EC_2.7.11.21-EC_2.7.11.30)102" style="font-size:114%;margin:0 4em"><a href="/wiki/Serine/threonine-specific_protein_kinase" title="Serine/threonine-specific protein kinase">Serine/threonine-specific protein kinases</a> (EC 2.7.11.21-EC 2.7.11.30)</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Polo_kinase" title="Polo kinase">Polo kinase</a> (EC 2.7.11.21)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/PLK1" title="PLK1">PLK1</a></li> <li><a href="/wiki/PLK2" title="PLK2">PLK2</a></li> <li><a href="/wiki/PLK3" title="PLK3">PLK3</a></li> <li><a href="/wiki/PLK4" title="PLK4">PLK4</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cyclin-dependent_kinase" title="Cyclin-dependent kinase">Cyclin-dependent kinase</a> (EC 2.7.11.22)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cdk1" class="mw-redirect" title="Cdk1">CDK1</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_2" title="Cyclin-dependent kinase 2">CDK2</a></li> <li><a href="/wiki/CDKL2" title="CDKL2">CDKL2</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_3" title="Cyclin-dependent kinase 3">CDK3</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_4" title="Cyclin-dependent kinase 4">CDK4</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_5" title="Cyclin-dependent kinase 5">CDK5</a></li> <li><a href="/wiki/CDKL5" title="CDKL5">CDKL5</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_6" title="Cyclin-dependent kinase 6">CDK6</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_7" title="Cyclin-dependent kinase 7">CDK7</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_8" title="Cyclin-dependent kinase 8">CDK8</a></li> <li><a href="/wiki/CDK9" class="mw-redirect" title="CDK9">CDK9</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_10" title="Cyclin-dependent kinase 10">CDK10</a></li> <li><a href="/wiki/CDK12" title="CDK12">CDK12</a></li> <li><a href="/wiki/CDC2L5" class="mw-redirect" title="CDC2L5">CDC2L5</a></li> <li><a href="/wiki/PCTK1" title="PCTK1">PCTK1</a></li> <li><a href="/wiki/PCTK2" title="PCTK2">PCTK2</a></li> <li><a href="/wiki/PCTK3" title="PCTK3">PCTK3</a></li> <li><a href="/wiki/PFTK1" title="PFTK1">PFTK1</a></li> <li><a href="/wiki/CDC2L1" title="CDC2L1">CDC2L1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/(RNA-polymerase)-subunit_kinase" title="(RNA-polymerase)-subunit kinase">(RNA-polymerase)-subunit kinase</a> (EC 2.7.11.23)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/RPS6KA5" title="RPS6KA5">RPS6KA5</a></li> <li><a href="/wiki/RPS6KA4" title="RPS6KA4">RPS6KA4</a></li> <li><a href="/wiki/P70S6_kinase" class="mw-redirect" title="P70S6 kinase">P70S6 kinase</a></li> <li><a href="/wiki/P70-S6_Kinase_1" title="P70-S6 Kinase 1">P70-S6 Kinase 1</a></li> <li><a class="mw-selflink selflink">RPS6KB2</a></li> <li><a href="/wiki/RPS6KA2" title="RPS6KA2">RPS6KA2</a></li> <li><a href="/wiki/RPS6KA3" title="RPS6KA3">RPS6KA3</a></li> <li><a href="/wiki/RPS6KA1" title="RPS6KA1">RPS6KA1</a></li> <li><a href="/wiki/RPS6KC1" title="RPS6KC1">RPS6KC1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Mitogen-activated_protein_kinase" title="Mitogen-activated protein kinase">Mitogen-activated protein kinase</a> (EC 2.7.11.24)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Extracellular_signal-regulated_kinases" title="Extracellular signal-regulated kinases">Extracellular signal-regulated</a> <ul><li><a href="/wiki/MAPK1" title="MAPK1">MAPK1</a></li> <li><a href="/wiki/MAPK3" title="MAPK3">MAPK3</a></li> <li><a href="/wiki/MAPK4" title="MAPK4">MAPK4</a></li> <li><a href="/wiki/MAPK6" title="MAPK6">MAPK6</a></li> <li><a href="/wiki/MAPK7" title="MAPK7">MAPK7</a></li> <li><a href="/wiki/MAPK12" title="MAPK12">MAPK12</a></li> <li><a href="/wiki/MAPK15" title="MAPK15">MAPK15</a></li></ul></li> <li><a href="/wiki/C-Jun_N-terminal_kinases" title="C-Jun N-terminal kinases">C-Jun N-terminal</a> <ul><li><a href="/wiki/MAPK8" title="MAPK8">MAPK8</a></li> <li><a href="/wiki/Mitogen-activated_protein_kinase_9" title="Mitogen-activated protein kinase 9">MAPK9</a></li> <li><a href="/wiki/MAPK10" title="MAPK10">MAPK10</a></li></ul></li> <li><a href="/wiki/P38_mitogen-activated_protein_kinases" title="P38 mitogen-activated protein kinases">P38 mitogen-activated protein</a> <ul><li><a href="/wiki/MAPK11" title="MAPK11">MAPK11</a></li> <li><a href="/wiki/MAPK13" title="MAPK13">MAPK13</a></li> <li><a href="/wiki/MAPK14" title="MAPK14">MAPK14</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/MAP_kinase_kinase_kinase" title="MAP kinase kinase kinase">MAP3K</a> (EC 2.7.11.25)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/MAP_kinase_kinase_kinase" title="MAP kinase kinase kinase">MAP kinase kinase kinases</a> <ul><li><a href="/wiki/MAP3K1" title="MAP3K1">MAP3K1</a></li> <li><a href="/wiki/MAP3K2" title="MAP3K2">MAP3K2</a></li> <li><a href="/wiki/MAP3K3" title="MAP3K3">MAP3K3</a></li> <li><a href="/wiki/MAP3K4" title="MAP3K4">MAP3K4</a></li> <li><a href="/wiki/ASK1" title="ASK1">MAP3K5</a></li> <li><a href="/w/index.php?title=MAP3K6&action=edit&redlink=1" class="new" title="MAP3K6 (page does not exist)">MAP3K6</a></li> <li><a href="/wiki/MAP3K7" title="MAP3K7">MAP3K7</a></li> <li><a href="/wiki/MAP3K8" title="MAP3K8">MAP3K8</a></li></ul></li> <li><a href="/wiki/C-Raf" title="C-Raf">RAFs</a> <ul><li><a href="/wiki/ARAF" title="ARAF">ARAF</a></li> <li><a href="/wiki/BRAF_(gene)" title="BRAF (gene)">BRAF</a></li> <li><a href="/wiki/KSR1" title="KSR1">KSR1</a></li> <li><a href="/wiki/KSR2" title="KSR2">KSR2</a></li></ul></li> <li><a href="/w/index.php?title=MLK_(kinase)&action=edit&redlink=1" class="new" title="MLK (kinase) (page does not exist)">MLKs</a> <ul><li><a href="/wiki/MAP3K12" title="MAP3K12">MAP3K12</a></li> <li><a href="/wiki/MAP3K13" title="MAP3K13">MAP3K13</a></li> <li><a href="/wiki/MAP3K9" title="MAP3K9">MAP3K9</a></li> <li><a href="/wiki/MAP3K10" title="MAP3K10">MAP3K10</a></li> <li><a href="/wiki/MAP3K11" title="MAP3K11">MAP3K11</a></li> <li><a href="/wiki/MAP3K7" title="MAP3K7">MAP3K7</a></li> <li><a href="/wiki/ZAK" title="ZAK">ZAK</a></li></ul></li> <li><a href="/wiki/Cell_division_cycle_7-related_protein_kinase" title="Cell division cycle 7-related protein kinase">CDC7</a></li> <li><a href="/wiki/MAP3K14" title="MAP3K14">MAP3K14</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tau-protein_kinase" title="Tau-protein kinase">Tau-protein kinase</a> (EC 2.7.11.26)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/TPK1" title="TPK1">TPK1</a></li> <li><a href="/wiki/TTK_(gene)" title="TTK (gene)">TTK</a></li> <li><a href="/wiki/GSK-3" title="GSK-3">GSK-3</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/(acetyl-CoA_carboxylase)_kinase" title="(acetyl-CoA carboxylase) kinase">(acetyl-CoA carboxylase) kinase</a> (EC 2.7.11.27)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>-</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tropomyosin_kinase" title="Tropomyosin kinase">Tropomyosin kinase</a> (EC 2.7.11.28)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>-</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Low-density-lipoprotein_receptor_kinase" title="Low-density-lipoprotein receptor kinase">Low-density-lipoprotein receptor kinase</a> (EC 2.7.11.29)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>-</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Receptor_protein_serine/threonine_kinase" title="Receptor protein serine/threonine kinase">Receptor protein serine/threonine kinase</a> (EC 2.7.11.30)</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bone_morphogenetic_protein_receptors" class="mw-redirect" title="Bone morphogenetic protein receptors">Bone morphogenetic protein receptors</a> <ul><li><a href="/wiki/Bone_morphogenetic_protein_receptor,_type_1" title="Bone morphogenetic protein receptor, type 1">BMPR1</a></li> <li><a href="/wiki/BMPR1A" title="BMPR1A">BMPR1A</a></li> <li><a href="/wiki/BMPR1B" title="BMPR1B">BMPR1B</a></li> <li><a href="/wiki/BMPR2" title="BMPR2">BMPR2</a></li></ul></li> <li><a href="/wiki/ACVR1" title="ACVR1">ACVR1</a></li> <li><a href="/wiki/ACVR1B" title="ACVR1B">ACVR1B</a></li> <li><a href="/wiki/ACVR1C" title="ACVR1C">ACVR1C</a></li> <li><a href="/wiki/ACVR2A" title="ACVR2A">ACVR2A</a></li> <li><a href="/wiki/ACVR2B" title="ACVR2B">ACVR2B</a></li> <li><a href="/wiki/ACVRL1" title="ACVRL1">ACVRL1</a></li> <li><a href="/wiki/Anti-M%C3%BCllerian_hormone_receptor" title="Anti-Müllerian hormone receptor">Anti-Müllerian hormone receptor</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Dual-specificity_kinases_(EC_2.7.12)102" style="font-size:114%;margin:0 4em"><a href="/wiki/Dual-specificity_kinase" title="Dual-specificity kinase">Dual-specificity kinases</a> (EC 2.7.12)</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="MAP2K49" scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Mitogen-activated_protein_kinase_kinase" title="Mitogen-activated protein kinase kinase">MAP2K</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/MAP2K1" title="MAP2K1">MAP2K1</a></li> <li><a href="/wiki/MAP2K2" title="MAP2K2">MAP2K2</a></li> <li><a href="/wiki/MAP2K3" title="MAP2K3">MAP2K3</a></li> <li><a href="/wiki/MAP2K4" title="MAP2K4">MAP2K4</a></li> <li><a href="/wiki/MAP2K5" title="MAP2K5">MAP2K5</a></li> <li><a href="/wiki/MAP2K6" title="MAP2K6">MAP2K6</a></li> <li><a href="/wiki/MAP2K7" title="MAP2K7">MAP2K7</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Enzymes56" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Enzymes" title="Template:Enzymes"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Enzymes" title="Template talk:Enzymes"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Enzymes" title="Special:EditPage/Template:Enzymes"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Enzymes56" style="font-size:114%;margin:0 4em"><a href="/wiki/Enzyme" title="Enzyme">Enzymes</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Activity</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Active_site" title="Active site">Active site</a></li> <li><a href="/wiki/Binding_site" title="Binding site">Binding site</a></li> <li><a href="/wiki/Catalytic_triad" title="Catalytic triad">Catalytic triad</a></li> <li><a href="/wiki/Oxyanion_hole" title="Oxyanion hole">Oxyanion hole</a></li> <li><a href="/wiki/Enzyme_promiscuity" title="Enzyme promiscuity">Enzyme promiscuity</a></li> <li><a href="/wiki/Diffusion-limited_enzyme" title="Diffusion-limited enzyme">Diffusion-limited enzyme</a></li> <li><a href="/wiki/Cofactor_(biochemistry)" title="Cofactor (biochemistry)">Cofactor</a></li> <li><a href="/wiki/Enzyme_catalysis" title="Enzyme catalysis">Enzyme catalysis</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Regulation</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Allosteric_regulation" title="Allosteric regulation">Allosteric regulation</a></li> <li><a href="/wiki/Cooperativity" title="Cooperativity">Cooperativity</a></li> <li><a href="/wiki/Enzyme_inhibitor" title="Enzyme inhibitor">Enzyme inhibitor</a></li> <li><a href="/wiki/Enzyme_activator" title="Enzyme activator">Enzyme activator</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Classification</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Enzyme_Commission_number" title="Enzyme Commission number">EC number</a></li> <li><a href="/wiki/Protein_superfamily" title="Protein superfamily">Enzyme superfamily</a></li> <li><a href="/wiki/Protein_family" title="Protein family">Enzyme family</a></li> <li><a href="/wiki/List_of_enzymes" title="List of enzymes">List of enzymes</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Kinetics</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Enzyme_kinetics" title="Enzyme kinetics">Enzyme kinetics</a></li> <li><a href="/wiki/Eadie%E2%80%93Hofstee_diagram" title="Eadie–Hofstee diagram">Eadie–Hofstee diagram</a></li> <li><a href="/wiki/Hanes%E2%80%93Woolf_plot" title="Hanes–Woolf plot">Hanes–Woolf plot</a></li> <li><a href="/wiki/Lineweaver%E2%80%93Burk_plot" title="Lineweaver–Burk plot">Lineweaver–Burk plot</a></li> <li><a href="/wiki/Michaelis%E2%80%93Menten_kinetics" title="Michaelis–Menten kinetics">Michaelis–Menten kinetics</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Types</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>EC1 <a href="/wiki/Oxidoreductase" title="Oxidoreductase">Oxidoreductases</a></b> (<a href="/wiki/List_of_EC_numbers_(EC_1)" title="List of EC numbers (EC 1)">list</a>)</li> <li><b>EC2 <a href="/wiki/Transferase" title="Transferase">Transferases</a></b> (<a href="/wiki/List_of_EC_numbers_(EC_2)" title="List of EC numbers (EC 2)">list</a>)</li> <li><b>EC3 <a href="/wiki/Hydrolase" title="Hydrolase">Hydrolases</a></b> (<a href="/wiki/List_of_EC_numbers_(EC_3)" title="List of EC numbers (EC 3)">list</a>)</li> <li><b>EC4 <a href="/wiki/Lyase" title="Lyase">Lyases</a></b> (<a href="/wiki/List_of_EC_numbers_(EC_4)" title="List of EC numbers (EC 4)">list</a>)</li> <li><b>EC5 <a href="/wiki/Isomerase" title="Isomerase">Isomerases</a></b> (<a href="/wiki/List_of_EC_numbers_(EC_5)" title="List of EC numbers (EC 5)">list</a>)</li> <li><b>EC6 <a href="/wiki/Ligase" title="Ligase">Ligases</a></b> (<a href="/wiki/List_of_EC_numbers_(EC_6)" title="List of EC numbers (EC 6)">list</a>)</li> <li><b>EC7 <a href="/wiki/Translocase" title="Translocase">Translocases</a></b> (<a href="/wiki/List_of_EC_numbers_(EC_7)" title="List of EC numbers (EC 7)">list</a>)</li></ul> </div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r1130092004">.mw-parser-output .portal-bar{font-size:88%;font-weight:bold;display:flex;justify-content:center;align-items:baseline}.mw-parser-output .portal-bar-bordered{padding:0 2em;background-color:#fdfdfd;border:1px solid #a2a9b1;clear:both;margin:1em auto 0}.mw-parser-output .portal-bar-related{font-size:100%;justify-content:flex-start}.mw-parser-output .portal-bar-unbordered{padding:0 1.7em;margin-left:0}.mw-parser-output .portal-bar-header{margin:0 1em 0 0.5em;flex:0 0 auto;min-height:24px}.mw-parser-output .portal-bar-content{display:flex;flex-flow:row wrap;flex:0 1 auto;padding:0.15em 0;column-gap:1em;align-items:baseline;margin:0;list-style:none}.mw-parser-output .portal-bar-content-related{margin:0;list-style:none}.mw-parser-output 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