ESCRS - The EPICAT study: Effectiveness of Periocular drug Injection in CATaract surgery

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<section class=" content-space-lg-1" style="background: url(/media/kqlmwzw0/white-full-width.png); background-repeat: no-repeat;background-size: cover; background-position-x: 60%;">  <div class="container content-space-1"> <div class="row justify-content-lg-between align-items-lg-center"> <div class="col"> <h1 class="w-lg-90 display-3 ">The EPICAT study: Effectiveness of Periocular drug Injection in CATaract surgery</h1> </div> </div> <div class="row justify-content-lg-between align-items-lg-center"> <div class="col col-lg-6"> <p class="fs-3 "></p> </div>  </div>  </div>  </section><section class="content-space-1 bg-light" style=""> <div class="umb-grid"> <div class="grid-section"> <div class="container"> <div class="row clearfix"> <div class="col-md-9 column"> <div > <p><strong>Summary</strong>: In Europe, over 4 million cataract surgeries are performed each year. A major cause of suboptimal vision following cataract surgery is cystoid macular edema (CME). In patients with CME, fluid accumulates in the central retinal area, due to leakage of blood vessels. Multiple cyst-like (cystoid) areas of fluid appear in the retina and cause retinal swelling or edema. Symptoms of CME are blurred and decreased vision. Anti-inflammatory eye drops are used after cataract surgery to prevent CME. However, noncompliance with eye drops is a major issue and may compromise the effectiveness of treatment.</p> <p>Noncompliance is often unintentional and related to forgetfulness or incorrect instillation, particularly in the elderly cataract surgery population. Because many patients have difficulty with self-instillation of eye drops, formal or informal care is often required. Administrating anti-inflammatory drugs with an injection in or around the eye during cataract surgery may obviate the need for eye drops after surgery.</p> <p>To investigate the effectiveness of anti-inflammatory drug delivery in or around the eye during cataract surgery, we propose to conduct a study in which 540 patients scheduled for cataract surgery will participate. Patients will be randomly divided over 3 treatment groups. One group will receive standard anti-inflammatory eye drops after cataract surgery. The other groups will receive a single or a combination of two anti-inflammatory drugs by injection in or around the eye during cataract surgery.</p> <p>Before and after cataract surgery we will measure the thickness of the central area of the retina, and compare this between groups. In addition, visual acuity and quality of life will be evaluated.</p> <p>We expect that administration of anti-inflammatory drugs during cataract surgery improves vision and comfort for patients and decreases costs. It may also alleviate the burden on homecare organizations.</p> </div> </div> <div class="col-md-3 column"> <div class="bg-white rounded-3 p-3"> <p class="mt-2 mb-0"><strong>Project leader</strong></p> <p class="m-0">Nienke Visser</p> <p class="m-0">The Netherlands</p> <p class="mt-2 mb-0"><strong>Amount awarded by ESCRS</strong></p> <p class="m-0">€749,707</p> <p class="mt-2 mb-0"><strong>Status</strong></p> <p class="m-0">PROJECT IN PROGRESS</p> </div> </div> </div> </div> </div> </div> </section> <section class="content-space-1 " style="">  <div class="overflow-hidden"> <div class="row align-items-md-center"> <div class="col-md mt-3"> <h3>EPICAT Resources</h3> </div>  <div class="col-md-auto mt-3">  <div class="js-swiper-button-prev-3410bea7-5276-4676-a6b6-92e5b0760212 swiper-button-prev swiper-static-button-prev"></div> <div class="js-swiper-button-next-3410bea7-5276-4676-a6b6-92e5b0760212 swiper-button-next swiper-static-button-next"></div> </div>  </div>   <div class="swiper-center-mode-end"> <div class="js-swiper-ub-3410bea7-5276-4676-a6b6-92e5b0760212 swiper swiper-step swiper-equal-height"> <div class="swiper-wrapper">  <div class="swiper-slide pt-4 pb-8"> <div class="card card-transition"> <div class="card-pinned"> <div class="position-relative"> <a data-fslightbox="lightbox" href="#vimeo13538"> <img class="card-img-top" src="/media/wvlfnnpd/epicat.jpg?width=300&height=200&rmode=crop&bgcolor=ffffff" alt="The EPICAT Study; an update from the project leader"> <div class="position-absolute top-50 start-50 translate-middle"> <svg xmlns="http://www.w3.org/2000/svg" width="64" height="64" fill="currentColor" class="bi bi-play-circle-fill text-primary" viewBox="0 0 16 16"> <path d="M6.79 5.093A.5.5 0 0 0 6 5.5v5a.5.5 0 0 0 .79.407l3.5-2.5a.5.5 0 0 0 0-.814l-3.5-2.5z" /> <path d="M0 4a2 2 0 0 1 2-2h12a2 2 0 0 1 2 2v8a2 2 0 0 1-2 2H2a2 2 0 0 1-2-2V4zm15 0a1 1 0 0 0-1-1H2a1 1 0 0 0-1 1v8a1 1 0 0 0 1 1h12a1 1 0 0 0 1-1V4z" /> </svg> </div> </a>  <div class="d-none"> <iframe src="https://player.vimeo.com/video/374162494" id="vimeo13538" class="fslightbox-source" width="1920" height=1080 frameBorder="0" allow="autoplay; fullscreen" allowFullScreen> </iframe> </div> <span class="badge bg-dark text-white card-pinned-top-end">Video</span> </div> </div> <div class="card-body"> <span class="card-subtitle text-primary">11 May 2020</span> <h6 class="card-title">The EPICAT Study; an update from the project leader</h6> <p class="fs-6 fw-light"></p> </div> <div class="card-footer pt-0"> <a class="card-link" href="/channels/education/the-epicat-study-an-update-from-the-project-leader/">Read more</a> </div> </div> </div>  </div>  <div class="js-swiper-preloader-3410bea7-5276-4676-a6b6-92e5b0760212 swiper-preloader"> <div class="spinner-border text-primary" role="status"> <span class="visually-hidden">Loading...</span> </div> </div>  </div> </div>  </div>  </section> <script> document.addEventListener("DOMContentLoaded", function (event) { // INITIALIZATION OF SWIPER // ======================================================= var swiper = new Swiper('.js-swiper-ub-3410bea7-5276-4676-a6b6-92e5b0760212', { navigation: { nextEl: '.js-swiper-button-next-3410bea7-5276-4676-a6b6-92e5b0760212', prevEl: '.js-swiper-button-prev-3410bea7-5276-4676-a6b6-92e5b0760212', }, slidesPerView: 1, breakpoints: { 380: { slidesPerView: 1, spaceBetween: 5, }, 768: { slidesPerView: 3, spaceBetween: 15, }, 1024: { slidesPerView: 4, spaceBetween: 15, }, 1100: { slidesPerView: 5, spaceBetween: 15, }, }, on: { 'imagesReady': function (swiper) { const preloader = swiper.el.querySelector('.js-swiper-preloader-3410bea7-5276-4676-a6b6-92e5b0760212') preloader.parentNode.removeChild(preloader) } }, autoHeight: false }); }); </script> <section class="bg-light content-space-1" style=""> <div class="umb-block-list"> <section class="container " style=""> <div class="umb-grid"> <div class="grid-section"> <div > <div class="row clearfix"> <div class="col-md-12 column"> <div > <h2>Past/Present ESCRS Research Projects</h2> <div class="table-responsive"> <table border="0" class="table table-striped"> <thead> <tr> <th scope="col">Project Leader</th> <th scope="col">Project Amount</th> <th scope="col">Title</th> <th scope="col">Status</th> <th scope="col"> </th> </tr> </thead> <tbody> <tr> <td>Dr. Jan Willem Beenakker <em>The Netherlands</em></td> <td>€650,195</td> <td><a href="/education/research-portals/virtual-refractive-surgery-for-the-prevention-of-negative-dysphotopsia-vrespond-study/" title="Virtual Refractive Surgery for the Prevention Of Negative Dysphotopsia (“vRESPOND”) study">Virtual Refractive Surgery for the Prevention Of Negative Dysphotopsia (“vRESPOND”)</a></td> <td><strong>COMPLETED</strong></td> <td><a href="/education/research-portals/virtual-refractive-surgery-for-the-prevention-of-negative-dysphotopsia-vrespond-study/" title="Virtual Refractive Surgery for the Prevention Of Negative Dysphotopsia (“vRESPOND”) study" class="link">View study</a></td> </tr> <tr> <td>Joaquim Carlos Neto Murta <em>Portugal</em></td> <td>€306,071</td> <td><a href="/education/research-portals/necsus-neuroadaptation-after-cataract-and-refractive-surgery-study/" title="NECSUS-Neuroadaptation after Cataract and Refractive Surgery Study">NECSUS-Neuroadaptation after Cataract and Refractive Surgery Study</a></td> <td><strong>COMPLETED</strong></td> <td><a href="/education/research-portals/necsus-neuroadaptation-after-cataract-and-refractive-surgery-study/" title="NECSUS-Neuroadaptation after Cataract and Refractive Surgery Study" class="link">View study</a></td> </tr> <tr> <td>Prof. Oliver Findl <em>Austria</em></td> <td>€549,643</td> <td><a href="/education/research-portals/influence-of-posterior-vitreous-detachment-on-retinal-detachment-after-lens-surgery-in-myopic-eyes-myopred/" title="Influence of posterior vitreous detachment on retinal detachment after lens surgery in myopic eyes (MYOPRED)">Influence of posterior vitreous detachment on retinal detachment after lens surgery in myopic eyes (MYOPRED)</a></td> <td>IN PROGRESS</td> <td><a href="/education/research-portals/influence-of-posterior-vitreous-detachment-on-retinal-detachment-after-lens-surgery-in-myopic-eyes-myopred/" title="Influence of posterior vitreous detachment on retinal detachment after lens surgery in myopic eyes (MYOPRED)" class="link">View study</a></td> </tr> <tr> <td>Nienke Visser <em>The Netherlands</em></td> <td>€749,707</td> <td><a href="/education/research-portals/the-epicat-study-effectiveness-of-periocular-drug-injection-in-cataract-surgery/" title="The EPICAT study: Effectiveness of Periocular drug Injection in CATaract surgery">The EPICAT study: Effectiveness of Periocular drug Injection in CATaract surgery</a></td> <td>IN PROGRESS</td> <td><a href="/education/research-portals/the-epicat-study-effectiveness-of-periocular-drug-injection-in-cataract-surgery/" title="The EPICAT study: Effectiveness of Periocular drug Injection in CATaract surgery" class="link">View study</a></td> </tr> <tr> <td>Mayank Nanavaty <em>UK</em></td> <td>€72,965.88</td> <td><a href="/education/research-portals/merov-the-monofocal-extended-range-of-vision-study/" title="MERoV: the Monofocal Extended Range of Vision Study">MERoV: the Monofocal Extended Range of Vision Study</a></td> <td>IN PROGRESS</td> <td><a href="/education/research-portals/merov-the-monofocal-extended-range-of-vision-study/" title="MERoV: the Monofocal Extended Range of Vision Study" class="link">View study</a></td> </tr> <tr> <td>Gary P. Misson <em>UK</em></td> <td>€29,780</td> <td><a href="/education/research-portals/cataract-age-related-macular-degeneration-and-polarization-perception-the-campol-study/" title="Cataract, age related Macular degeneration and Polarization perception: the “CaMPoL Study">Cataract, age related Macular degeneration and Polarization perception: the “CaMPoL Study”</a></td> <td>IN PROGRESS</td> <td><a href="/education/research-portals/cataract-age-related-macular-degeneration-and-polarization-perception-the-campol-study/" title="Cataract, age related Macular degeneration and Polarization perception: the “CaMPoL Study" class="link">View study</a></td> </tr> <tr> <td>Rudy Nuijts <em>The Netherlands</em></td> <td>--</td> <td><a href="/education/research-portals/prevention-of-macular-edema-after-cataract-surgery-premed/" title="PREvention of Macular EDema after cataract surgery (PREMED)">PREvention of Macular EDema after cataract surgery (PREMED) Study Portal</a></td> <td><strong>COMPLETED</strong></td> <td><a href="/education/research-portals/prevention-of-macular-edema-after-cataract-surgery-premed/" title="PREvention of Macular EDema after cataract surgery (PREMED)" class="link">View study</a></td> </tr> <tr> <td>Peter Barry <em>Ireland</em></td> <td>--</td> <td><a href="/education/research-portals/the-endophthalmitis-study/" title="The Endophthalmitis Study">Endophthalmitis Study Portal</a></td> <td><strong>COMPLETED</strong></td> <td><a href="/education/research-portals/the-endophthalmitis-study/" title="The Endophthalmitis Study" class="link">View study</a></td> </tr> </tbody> </table> </div> </div> </div> </div> </div> </div> </div> </section></div> </section></div> </div> </div>  <footer class="bg-dark"> <div class="container"> <div class="row align-items-center pt-8 pb-4"> <div class="col-md mb-5 mb-md-0"> <img src="/media/u1yhmfxx/escrs-white.png?width=250" classs="img-fluid" /> </div>  <div class="col-md-auto"> <div class="d-grid 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