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href="https://sciprofiles.com/profile/author/MzE5V1hLeVBDeEZlajdVUm56eDdOWERoYXlNNzVGTkYxeGZOVWUra1dxZz0=" target="_blank" rel="noopener noreferrer">Roland Derwand</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><span><a href="https://sciprofiles.com/profile/author/YkIySFZWWU1hS0hFNUpmQllSK2REcXhKOXFLV0ZqZVNaL25yTTZoN2ovQT0=" target="_blank" rel="noopener noreferrer">Vladimir Zelenko</a></span></span></span></div><div class="invisible absolute"><span class="pr-sm"><span class="m-text text-sm"><div class="m-avatar flex items-center justify-center overflow-hidden rounded-full bg-brand-bold font-medium text-color-on-brand h-5 w-5 min-w-5 text-[0.575rem] !inline-block align-middle mr-xs" data-testid="m-avatar"><img src="/statics/img/design/default-user.png"><span class="sr-only"></span></div><span><a href="https://sciprofiles.com/profile/1042958" target="_blank" rel="noopener noreferrer">Martin Scholz</a></span><sup> *</sup><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><span><a href="https://sciprofiles.com/profile/author/MzE5V1hLeVBDeEZlajdVUm56eDdOWERoYXlNNzVGTkYxeGZOVWUra1dxZz0=" target="_blank" rel="noopener noreferrer">Roland Derwand</a></span><span>,</span></span></span><span class="pr-sm"><span class="m-text text-sm"><span><a href="https://sciprofiles.com/profile/author/YkIySFZWWU1hS0hFNUpmQllSK2REcXhKOXFLV0ZqZVNaL25yTTZoN2ovQT0=" target="_blank" rel="noopener noreferrer">Vladimir Zelenko</a></span></span></span></div></div><div style="display:none;" class="mt-sm"><button class="m-button m-button--sm m-button--tertiary rounded !inline-flex after:hidden bg-white" type="button"><span class="inline-flex h-full w-full items-center gap-2 whitespace-nowrap justify-center">Show more <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" data-testid="keyboard_arrow_down" style="" width="16" height="16" viewBox="0 0 16 16"></svg></span></button></div></div><p class="m-text text-sm text-color-error pt-sm">This version is not peer-reviewed</p></div><div class="m-accordion mx-auto flex w-full flex-col gap-3 rounded-2xl bg-white"><div class="m-accordion__item border-b border-color-default"><button id="accordion-button-expand-0" aria-controls="accordion-panel-0" class="relative mb-xs flex w-full cursor-pointer py-md text-sm outline-offset-2" aria-expanded="true"><span class="text-sm">This preprints belongs to the Collection</span><div class="absolute right-0 top-1/2 -translate-y-1/2"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" data-testid="keyboard_arrow_down" class="origin-center transition duration-150 rotate-180" style="" width="16" height="16" viewBox="0 0 16 16"></svg></div></button><div id="accordion-panel-0" aria-labelledby="accordion-button-expand-0" role="region" class="m-accordion__body overflow-hidden transition-height duration-150"><div class="break-words pb-md"><div class="flex items-center"><p class="m-text text-sm text-color-link-bold cursor-pointer">Preprints on COVID-19 and SARS-CoV-2</p><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" data-testid="arrow_right_alt" class="text-color-link-bold cursor-pointer" style="" width="16" height="16" viewBox="0 0 16 16"></svg></div></div></div></div></div></div><div class="py-md border-b border-color-default"><div class="m-select common-field bg-white"><div class="common-field__wrapper" data-headlessui-state><div class="relative w-full cursor-default"><div class="flex items-center"><button id="headlessui-listbox-button-mui-127996" type="button" aria-haspopup="listbox" aria-expanded="false" data-headlessui-state data-testid="select-activator" class="common-field__dropdown-input [&>span]:overflow-hidden h-10"><span class="flex w-full items-center gap-1 [&>span]:truncate"><span>Version 1</span></span><div class="flex"><svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" aria-hidden="true" role="img" data-testid="keyboard_arrow_down" class="duration-400 transition-transform" style="" width="24" height="24" viewBox="0 0 16 16"></svg></div></button></div></div></div></div><div class="pt-sm"><div class="flex"><p class="m-text text-xs">Submitted:</p><p class="m-text text-xs pl-xs">30 June 2020</p></div><div class="flex pt-sm"><p class="m-text text-xs">Posted: </p><p class="m-text text-xs pl-xs">03 July 2020</p></div></div><div class="pt-sm"><div><p class="m-text text-xs">You are already at the latest version </p></div></div><div></div></div><div class="py-md border-b border-color-default flex items-center justify-between" data-v-d8c082ee><div class="flex-none flex items-center" data-v-d8c082ee><span class="m-text text-xs pr-xs font-semibold flex-none" data-v-d8c082ee>Alerts</span><span data-v-d8c082ee></span></div><div class="m-switch flex items-center gap-2" data-v-d8c082ee><button class="relative inline-flex h-[1.4rem] w-[2.75rem] shrink-0 cursor-pointer items-center rounded-full border-2 border-color-transparent transition-colors duration-150 ease-out ui-focus-visible:ring-2 ui-focus-visible:ring-brand-bold ui-focus-visible:ring-opacity-75 bg-content-default hover:bg-content-bold active:bg-content-bolder" aria-label="Switch on" id="headlessui-switch-mui-127997" role="switch" type="button" tabindex="0" aria-checked="false" data-headlessui-state><span aria-hidden="true" class="pointer-events-none inline-block h-[1rem] w-[1rem] transform rounded-full bg-white shadow-lg ring-0 transition duration-200 ease-in-out translate-x-0.5"></span></button></div></div><div data-v-d8c082ee data-v-03f1a75d></div><div><h6 class="m-heading text-inherit m-h6 font-semibold pt-lg">Abstract</h6><div class=""><em>Objective: </em>To describe outcomes of patients with coronavirus disease 2019 (COVID-19) in the outpatient setting after early treatment with zinc, low dose hydroxychloroquine, and azithromycin (the triple therapy) dependent on risk stratification. <em>Design:</em> Retrospective case series study. <em>Setting:</em> General practice. <em>Participants:</em> 141 COVID-19 patients with laboratory confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the year 2020. <em>Main Outcome Measures:</em> Risk-stratified treatment decision, rate of hospitalization and all-cause death. <em>Results: </em>Of 335 positively PCR-tested COVID-19 patients, 127 were treated with the triple therapy. 104 of 127 met the defined risk stratification criteria and were included in the analysis. In addition, 37 treated and eligible patients who were confirmed by IgG tests were included in the treatment group (total N=141). 208 of the 335 patients did not meet the risk stratification criteria and were not treated. After 4 days (median, IQR 3-6, available for N=66/141) of onset of symptoms, 141 patients (median age 58 years, IQR 40-67; 73% male) got a prescription for the triple therapy for 5 days. Independent public reference data from 377 confirmed COVID-19 patients of the same community were used as untreated control. 4 of 141 treated patients (2.8%) were hospitalized, which was significantly less (p<0.001) compared with 58 of 377 untreated patients (15.4%) (odds ratio 0.16, 95% CI 0.06-0.5). Therefore, the odds of hospitalization of treated patients were 84% less than in the untreated group. One patient (0.7%) died in the treatment group versus 13 patients (3.5%) in the untreated group (odds ratio 0.2, 95% CI 0.03-1.5; p=0.16). There were no cardiac side effects. <em>Conclusions:</em> Risk stratification-based treatment of COVID-19 outpatients as early as possible after symptom onset with the used triple therapy, including the combination of zinc with low dose hydroxychloroquine, was associated with significantly less hospitalizations and 5 times less all-cause deaths.</div></div><div data-v-3ce94018><div class="pt-lg" data-v-3ce94018><span class="m-text text-body font-semibold" data-v-3ce94018>Keywords: </span><span class="m-text text-body pt-sm" data-v-3ce94018></span></div></div><div class="flex-1 pt-lg mr-lg lg:pt-0" data-v-da90062a><div class="pt-md" data-v-da90062a><div class="flex flex-wrap lg:flex-nowrap items-center" data-v-da90062a><span class="m-text text-body font-semibold" data-v-da90062a>Subject: </span><span class="m-text text-body" data-v-da90062a>Medicine and Pharmacology</span><span class="" data-v-da90062a> - </span><span class="m-text text-body" 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Stay updated on the latest research shaping the dynamic and ever-evolving field of engineering.",{"id":89,"name":90,"name_system":91,"parent_id":50,"image_banner":92,"description":93,"converted_name_system":94},113,"Environmental and Earth Sciences","environmental_and_earth_sciences","https://www.preprints.org/media/cache/resolve/webp/upload/subject/2024-11-07/427574c3272a512b9412d12b3bfb3f51.jpg","Investigate the dynamic processes shaping our planet with our preprints. From atmospheric phenomena to oceanography, explore the interconnected systems of our planet and the innovative solutions shaping its future. Stay informed on research that impacts our environment and sustainability.","environmental-and-earth-sciences",{"id":96,"name":97,"name_system":98,"parent_id":50,"image_banner":99,"description":100,"converted_name_system":101},130,"Medicine and Pharmacology","medicine_and_pharmacology","https://www.preprints.org/media/cache/resolve/webp/upload/subject/2024-11-07/98c86d1fdf40abfda51ca959f75f3499.jpg","Embark on a journey through the vast world of medicine and pharmacology with our preprints. Explore breakthroughs in healthcare, from cardiology to neurology, which improve human health outcomes. Delve into the frontiers of medical research and pharmaceutical development that enhance quality of life.","medicine-and-pharmacology",{"id":103,"name":104,"name_system":105,"parent_id":50,"image_banner":106,"description":107,"converted_name_system":108},166,"Physical Sciences","physical_sciences","https://www.preprints.org/media/cache/resolve/webp/upload/subject/2024-11-07/c2d6e400b105b8c3d32ec59f26ab969d.jpg","Explore the fundamental laws governing matter and energy in the universe with our preprints. From quantum mechanics to cosmology, stay abreast of research that advances our understanding of the natural world. Dive into a world of scientific discovery that pushes the boundaries of knowledge.","physical-sciences",{"id":110,"name":111,"name_system":112,"parent_id":50,"image_banner":113,"description":114,"converted_name_system":115},185,"Public Health and Healthcare","public_health_and_healthcare","https://www.preprints.org/media/cache/resolve/webp/upload/subject/2024-11-07/ef7c6de55fa117659c3b6090edc7c4ff.jpg","Examine critical issues in public health policy, epidemiology, and healthcare systems with our preprints. Stay updated on research into health disparities, infectious disease control, and healthcare management, which informs public health interventions. Explore the latest trends in healthcare that impact population well-being and equity.","public-health-and-healthcare",{"id":117,"name":118,"name_system":119,"parent_id":50,"image_banner":120,"description":121,"converted_name_system":122},193,"Social Sciences","social_sciences","https://www.preprints.org/media/cache/resolve/webp/upload/subject/2024-09-12/910c960e3a6808861523728f0f26b2df.png","Gain insights into human behavior, societies, and cultures with our preprints. Explore disciplines like psychology, sociology, and political science, which shape our world and inform public policy. Stay engaged with research that explores social issues, cultural dynamics, and economic systems, enriching our understanding of human interactions.","social-sciences",{"code":41,"msg":42,"data":124},{"temp_id":125,"version":7,"id":126,"hash_key":127,"doi":128,"article_abstract":129,"article_title":130,"keywords":131,"is_registering_doi":132,"mdpi_topic":50,"preprints_collections":133,"subject":137,"top_subject":140,"article_type":141,"submitted_at":144,"published_at":145,"last_edited_at":50,"authors":146,"ethical_approval":6,"ethical_approval_number":165,"ethical_approval_body":166,"ethical_approval_for_publication":132,"article_supplementary":50,"final_file":167,"graphic_abstract":171,"statistics":172,"is_peer_reviewed":6,"peer_reviewed_article_url":175,"almetric":176,"preserved_by_portico":6,"ms_xml":50,"versions":179,"citation":181,"peer_reviewed_citation":182,"version_changes":183,"updating_alert_registered":132,"preprints_process_url":50,"comments_count":184,"latest_version":7,"author_notes":185,"withdrawed_at":50,"is_withdrwan":132},29134,"202007.0025","2b8171df5f247daef6bc53f7dc9457c4","10.20944/preprints202007.0025.v1","\u003Cem>Objective: \u003C/em>To describe outcomes of patients with coronavirus disease 2019 (COVID-19) in the outpatient setting after early treatment with zinc, low dose hydroxychloroquine, and azithromycin (the triple therapy) dependent on risk stratification. \u003Cem>Design:\u003C/em> Retrospective case series study. \u003Cem>Setting:\u003C/em> General practice. \u003Cem>Participants:\u003C/em> 141 COVID-19 patients with laboratory confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the year 2020. \u003Cem>Main Outcome Measures:\u003C/em> Risk-stratified treatment decision, rate of hospitalization and all-cause death. \u003Cem>Results: \u003C/em>Of 335 positively PCR-tested COVID-19 patients, 127 were treated with the triple therapy. 104 of 127 met the defined risk stratification criteria and were included in the analysis. In addition, 37 treated and eligible patients who were confirmed by IgG tests were included in the treatment group (total N=141). 208 of the 335 patients did not meet the risk stratification criteria and were not treated. After 4 days (median, IQR 3-6, available for N=66/141) of onset of symptoms, 141 patients (median age 58 years, IQR 40-67; 73% male) got a prescription for the triple therapy for 5 days. Independent public reference data from 377 confirmed COVID-19 patients of the same community were used as untreated control. 4 of 141 treated patients (2.8%) were hospitalized, which was significantly less (p<0.001) compared with 58 of 377 untreated patients (15.4%) (odds ratio 0.16, 95% CI 0.06-0.5). Therefore, the odds of hospitalization of treated patients were 84% less than in the untreated group. One patient (0.7%) died in the treatment group versus 13 patients (3.5%) in the untreated group (odds ratio 0.2, 95% CI 0.03-1.5; p=0.16). There were no cardiac side effects. \u003Cem>Conclusions:\u003C/em> Risk stratification-based treatment of COVID-19 outpatients as early as possible after symptom onset with the used triple therapy, including the combination of zinc with low dose hydroxychloroquine, was associated with significantly less hospitalizations and 5 times less all-cause deaths.","COVID-19 Outpatients – Early Risk-Stratified Treatment with Zinc Plus Low Dose Hydroxychloroquine and Azithromycin: A Retrospective Case Series Study","SARS-CoV-2; COVID-19; outpatients; treatment; zinc; hydroxychloroquine; azithromycin",false,[134],{"title":135,"id":7,"name_system":136},"Preprints on COVID-19 and SARS-CoV-2","covid19",{"id":138,"name":139},157,"Pharmacy",{"id":96,"name":97},{"id":142,"name":143},15,"Article","2020-06-30 22:01:06","2020-07-03 08:52:22",[147,154,160],{"id":148,"name":149,"email":150,"is_corresponding":6,"orcid_link":50,"author_mark":151,"sp_link":152,"avatar":153},127466,"Martin Scholz","martin.scholz@leukocare.com","*","https://sciprofiles.com/profile/1042958","/statics/img/design/default-user.png",{"id":155,"name":156,"email":157,"is_corresponding":132,"orcid_link":50,"author_mark":158,"sp_link":159,"avatar":50},127467,"Roland Derwand","roland.derwand@gmx.de","","https://sciprofiles.com/profile/author/MzE5V1hLeVBDeEZlajdVUm56eDdOWERoYXlNNzVGTkYxeGZOVWUra1dxZz0=",{"id":161,"name":162,"email":163,"is_corresponding":132,"orcid_link":50,"author_mark":158,"sp_link":164,"avatar":50},127468,"Vladimir Zelenko","zz613@hotmail.com","https://sciprofiles.com/profile/author/YkIySFZWWU1hS0hFNUpmQllSK2REcXhKOXFLV0ZqZVNaL25yTTZoN2ovQT0=","D4-Excemption-Zelenko (06-16-2020)","Western Institutional Review Board",{"filename":168,"url":169,"filesize":170},"final_file.pdf","/frontend/manuscript/2b8171df5f247daef6bc53f7dc9457c4/download_pub",397344,[],{"viewed":173,"downloaded":174},"308704","42094","https://www.sciencedirect.com/science/article/pii/S0924857920304258",{"score":177,"detail_url":178},4361,"https://preprints.altmetric.com/details/doi/10.20944/preprints202007.0025.v1",[180],{"version":7,"hash_key":127,"id":126,"change":50},"Scholz, M.; Derwand, R.; Zelenko, V. COVID-19 Outpatients – Early Risk-Stratified Treatment with Zinc Plus Low Dose Hydroxychloroquine and Azithromycin: A Retrospective Case Series Study. \u003Cem>Preprints\u003C/em> \u003Cb>2020\u003C/b>, 2020070025. https://doi.org/10.20944/preprints202007.0025.v1","Derwand, R.; Scholz, M.; Zelenko, V. COVID-19 Outpatients: Early Risk-Stratified Treatment with Zinc plus Low-Dose Hydroxychloroquine and Azithromycin: A Retrospective Case Series Study. International Journal of Antimicrobial Agents 2020, 56, 106214, doi:10.1016/j.ijantimicag.2020.106214.",[],77,[],{"code":41,"msg":42,"data":187},[188,192],{"id":7,"name":189,"image":190,"url":191,"statistic_type":7},"Author 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Guérin","guerinviolaine@gmail.com",{"name":208,"email":209},"Pierre Lévy","pierre.levy@aphp.fr",{"name":211,"email":212},"Jean-Louis Thomas","jlthomas@numericable.fr",{"name":214,"email":215},"Thierry Lardenois","lardenois.thierry@wanadoo.fr",{"name":217,"email":218},"Philippe Lacrosse","philippe.lacrosse@mac.com",{"name":220,"email":221},"Emmanuel Sarrazin","sarrazinemmanuel@gmail.com",{"name":223,"email":224},"Natacha Regensberg de Andreis","nrda@dbmail.com",{"name":226,"email":227},"Martine Wonner","martine.wonner@gmail.com","2020-05-31","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfuMgHRjixO5qNXAd9NhHkXwz59Xeg9VMIlbQJnIU4OTmMAQqp7NbgC34rx42C4x3Cg",{"doi":231,"title":232,"url":233,"authors":234,"published_at":265,"journal_name":50,"click_trigger_url_hash":266},"10.20944/preprints202310.0252.v1","Impact of the Main Pharmacological Option and Risk Factors for COVID-19 Disease Progression in Hospitalized Patients in Northern Italy: A Single-Center Retrospective Study","https://doi.org/10.20944/preprints202310.0252.v1",[235,238,241,244,247,250,253,256,259,262],{"name":236,"email":237},"Cesare Bolla","cesare.bolla@ospedale.al.it",{"name":239,"email":240},"Serena Penpa","serena.penpa@ospedale.al.it",{"name":242,"email":243},"Eleonora Sarchi","eleonora.sarchi@ospedale.al.it",{"name":245,"email":246},"Andrea Schimmenti","andrea.schimmenti@ospedale.al.it",{"name":248,"email":249},"Giorgia Piceni","giorgia.piceni@ospedale.al.it",{"name":251,"email":252},"Marinella Bertolotti","mbertolotti@ospedale.al.it",{"name":254,"email":255},"Simona Panzacchi","panzacchis@ramazzini.it",{"name":257,"email":258},"Daniele Mandrioli","mandriolid@ramazzini.it",{"name":260,"email":261},"Guido Chichino","guido.chichino@ospedale.al.it",{"name":263,"email":264},"Antonio Maconi","amaconi@ospedale.al.it","2023-10-05","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfhrMackktWQGpuHnwRSkviGACiPzcd5yzTO5pL3_RCJ_xeIo44gsTPmjBxBdrfQG_g",{"doi":268,"title":269,"url":270,"authors":271,"published_at":287,"journal_name":50,"click_trigger_url_hash":288},"10.20944/preprints202103.0602.v2","Symptoms and Underlying Diseases Associated with the Hospitalization Period of 3480 Covid-19 Patients in Hormozgan, Iran\u003Cstrong> \u003C/strong>","https://doi.org/10.20944/preprints202103.0602.v2",[272,275,278,281,284],{"name":273,"email":274},"Hesamuddin Kamalzadeh Takhti","ehsanamiri1@sums.ac.ir",{"name":276,"email":277},"Mahdieh Ardaneh","ehsanamiri3@sums.ac.ir",{"name":279,"email":280},"Shahram Zare","ehsanamiri2@sums.ac.ir",{"name":282,"email":283},"Maryam Rezaei Sarkhaei","ehsanamiri4@sums.ac.ir",{"name":285,"email":286},"Ehsan Amiri-Ardekani","ehsanamiri@sums.ac.ir","2021-05-10","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfh0Q3-HrWegvIW0mrvi78e78fBKIYeuSgVX5p8XZS97A3D6B82_l2KiyEnlM0PtKkg",{"doi":290,"title":291,"url":292,"authors":293,"published_at":312,"journal_name":50,"click_trigger_url_hash":313},"10.20944/preprints202306.1417.v1","Clinical and Epidemiological Risk Factors Associated with Hospitalization and Mortality Rate of COVID-19 Patients in Banja Luka County: Retrospective Observational Cohort Study on 40,000 patients","https://doi.org/10.20944/preprints202306.1417.v1",[294,297,300,303,306,309],{"name":295,"email":296},"Nataša Pilipović-Broćeta","natasa.pilipovic-broceta@med.unibl.org",{"name":298,"email":299},"Nevena Todorović","nevena.todorovic@med.unibl.org",{"name":301,"email":302},"Ranko Škrbić","ranko.skrbic@med.unibl.org",{"name":304,"email":305},"Jela Aćimović","jela.acimovic@med.unibl.org",{"name":307,"email":308},"Savka Štrbac","savka.strbac@phi.rs.ba",{"name":310,"email":311},"Ivan Soldatović","soldatovic.ivan@gmail.com","2023-06-20","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfm_dFqxUcfu18rzFip34tXeAfkcgrjEorRV92dMBAMcnRVB1C1iPiZf7ADu6r0rDrw",{"doi":315,"title":316,"url":317,"authors":318,"published_at":349,"journal_name":50,"click_trigger_url_hash":350},"10.20944/preprints202008.0283.v1","\u003Cstrong>Suspected Serious Adverse Drug Reactions in Hospitalized COVID-19 Patients\u003C/strong>","https://doi.org/10.20944/preprints202008.0283.v1",[319,322,325,328,331,334,337,340,343,346],{"name":320,"email":321},"Elena Ramírez","elena.ramirez@uam.es",{"name":323,"email":324},"Mikel Urroz","mikel.urroz@salud.madrid.org",{"name":326,"email":327},"Amelia Rodríguez Mariblanca","ameliarmb.ucicec@gmail.com",{"name":329,"email":330},"Alberto Martín-Vega","amartinv@salud.madrid.org",{"name":332,"email":333},"Yuri Villán","yurifabiola.villan@gmail.com",{"name":335,"email":336},"Enrique Seco","enriquesm.ucicec@gmail.com",{"name":338,"email":339},"Jaime Monserrat","jaime.monserrat@salud.madrid.org",{"name":341,"email":342},"Jesús Frías","jesus.frias@uam.es",{"name":344,"email":345},"Antonio J. Carcas","antonio.carcas@uam.es",{"name":347,"email":348},"Alberto M. Borobia","alberto.borobia@salud.madrid.org","2020-08-12","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfnSNsWgmD5bN-yr6FvSwS36YMZSxS6mjhxIlXzcPl8pPMKLa2ykSh2J3iC0-UnNHMA",{"doi":50,"title":352,"url":353,"authors":354,"published_at":382,"journal_name":50,"click_trigger_url_hash":383},"Clinical Characteristics, Laboratory Findings, Radiographic Signs and Outcomes of 52,251 Patients with Confirmed COVID-19 Infection: A Systematic Review and Meta-Analysis","https://doi.org/",[355,358,361,364,367,370,373,376,379],{"name":356,"email":357},"Ali Pormohammad","pormohammadali@yahoo.com",{"name":359,"email":360},"Saeed Ghorbani","vet.s.ghorbani@gmail.com",{"name":362,"email":363},"Behzad Baradaran","baradaranb@tbzmed.ac.ir",{"name":365,"email":366},"Alireza Khatam","akh.alirezakhatami@gmail.com",{"name":368,"email":369},"Raymond Turner","turnerr@ucalgary.ca",{"name":371,"email":372},"Mohammad Ali Mansournia","mansournia_m@sina.tums.ac.ir",{"name":374,"email":375},"Demetrios N. Kyriacou","d-kyriacou@northwestern.edu",{"name":377,"email":378},"Juan-Pablo Idrovo","juan.idrovo@cuanschutz.edu",{"name":380,"email":381},"Nathan C. Bahr","nate.bahr@gmail.com","2020-03-16","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfsXWJSG2TQyJ5HsQ3cf-CGCa0KKFEi0Zaxs4Y-_HPW9oBjjgqgWqKjc0-hzP2Mi_gg",{"doi":385,"title":386,"url":387,"authors":388,"published_at":410,"journal_name":50,"click_trigger_url_hash":411},"10.20944/preprints202401.1613.v1","Vaccination and Patient Status of Long COVID-19 Hospitalized Patients: A Cohort Observational Study","https://doi.org/10.20944/preprints202401.1613.v1",[389,392,395,398,401,404,407],{"name":390,"email":391},"Simona Kirbiš","simona.kirbis@zd-mb.si",{"name":393,"email":394},"Nina Sobotkiewicz","nina.sobotkiewicz@zd-mb.si",{"name":396,"email":397},"Barbara Antolinc Schaubach","barbara.antolinc@zd-mb.si",{"name":399,"email":400},"Jernej Završnik","jernej.zavrsnik@zd-mb.si",{"name":402,"email":403},"Peter Kokol","peter.kokol@um.si",{"name":405,"email":406},"Matej Završnik","matej.zavrsnik@ukc-mb.si",{"name":408,"email":409},"Helena Blažun Vošner","helena.blazun@zd-mb.si","2024-01-23","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfscy6wNtmigSshE0hjl7R7jjDVwa8pa5cHmjVwvog5s94dvaakT51RfFifW9YV4OWg",{"doi":413,"title":414,"url":415,"authors":416,"published_at":471,"journal_name":50,"click_trigger_url_hash":472},"10.20944/preprints202203.0277.v1","Collaborative Research for Long COVID Haulers in Greece (Characteristics, Clinical Assessment and Rehabilitation). Non-hospitalized and Hospitalized Long COVID Patients Share Similar Symptom Patterns","https://doi.org/10.20944/preprints202203.0277.v1",[417,420,423,426,429,432,435,438,441,444,447,450,453,456,459,462,465,468],{"name":418,"email":419},"Martha Spyridoula Katsarou","mskatsarou@gmail.com",{"name":421,"email":422},"Eleni Iasonidou","iasonidouhelen@hotmail.com",{"name":424,"email":425},"Alexander Osarogue","a.osarogue@gmail.com",{"name":427,"email":428},"Efthymios Kalafatis","themos.kalafatis@gmail.com",{"name":430,"email":431},"Stylianos Gatzonis","sgatzon@med.uoa.gr",{"name":433,"email":434},"Sofia Pappa","sofia.pappa@westlondon.nhs.uk",{"name":436,"email":437},"Athanasia Verentzioti","nverentzioti@gmail.com",{"name":439,"email":440},"Maria Stefanatou","marwstef@gmail.com",{"name":442,"email":443},"Pantelis Gounopoulos","gounopoulos@yahoo.gr",{"name":445,"email":446},"Christos Demponeras","ch_demponeras@hotmail.com",{"name":448,"email":449},"Eleni Konstantinidou","el.kon@outlook.com.gr",{"name":451,"email":452},"Nikolaos Drakoulis","drakoulis@pharm.uoa.gr",{"name":454,"email":455},"Andreas Asimakos","silverakos@gmail.com",{"name":457,"email":458},"Archontoula Antonoglou","arxoantonoglou@gmail.com",{"name":460,"email":461},"Aspasia Mavronasou","aspasiamavronasou@hotmail.com",{"name":463,"email":464},"Stavroula Spetsioti","roula_spe@hotmail.com",{"name":466,"email":467},"Anastasia Kotanidou","akotanid@med.uoa.gr",{"name":469,"email":470},"Paraskevi Katsaounou","paraskevikatsaounou@gmail.com","2022-03-21","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfv6UAIk96H8KP2jM-lrXCXfdexEff0QjLvpJxajj0WK8JoqNQuWfnLDigz5lsaygAQ",{"doi":474,"title":475,"url":476,"authors":477,"published_at":534,"journal_name":50,"click_trigger_url_hash":535},"10.20944/preprints202005.0057.v2","Early Hydroxychloroquine Is Associated with an Increase of Survival in COVID-19 Patients: An Observational Study","https://doi.org/10.20944/preprints202005.0057.v2",[478,481,484,487,490,493,496,498,501,504,507,510,513,516,519,522,525,528,531],{"name":479,"email":480},"Francisco Javier Membrillo","javimembrillo@gmail.com",{"name":482,"email":483},"Germán Ramírez-Olivencia","germanro.76@gmail.com",{"name":485,"email":486},"Miriam Estébanez","mirestmun@gmail.com",{"name":488,"email":489},"Begoña de Dios","bdedgar@mde.es",{"name":491,"email":492},"María Dolores Herrero","mherme2@mde.es",{"name":494,"email":495},"Tatiana Mata","tmatfor@oc.mde.es",{"name":347,"email":497},"a.borobia@gmail.com",{"name":499,"email":500},"Carlos Gutiérrez","cgutort@oc.mde.es",{"name":502,"email":503},"María Simón","msimsac@oc.mde.es",{"name":505,"email":506},"Ana Ochoa","aochrui@mde.es",{"name":508,"email":509},"Yolanda Martínez","ymarma1@oc.mde.es",{"name":511,"email":512},"Alejandro Aguirre","aaguivil@oc.mde.es",{"name":514,"email":515},"Francisco de Asís Alcántara","falcnic@oc.mde.es",{"name":517,"email":518},"Pablo Fernández-González","pfergo7@mde.es",{"name":520,"email":521},"Elena López","eloptiz@oc.mde.es",{"name":523,"email":524},"Paula Valle","paula.ucicec@gmail.com",{"name":526,"email":527},"Sergio Campos","scamtel@oc.mde.es",{"name":529,"email":530},"María Navarro","mnavtel@oc.mde.es",{"name":532,"email":533},"Lucía Elena Ballester","lbalorc@oc.mde.es","2020-05-09","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfoeIaPhiKQFclu-jngTqGxbcO6a5pFT0FOm1V8F7UDXClMuOs2bW-KbLmYRou6MhXA",{"doi":537,"title":538,"url":539,"authors":540,"published_at":553,"journal_name":50,"click_trigger_url_hash":554},"10.20944/preprints202309.0132.v1","Clinical Features and Outcomes of Association of Co-infections in Children with LaboratoryConfirmed Influenza, during 2022–2023 Season; a Romanian Perspective ","https://doi.org/10.20944/preprints202309.0132.v1",[541,544,547,550],{"name":542,"email":543},"Maria Madalina Merisescu","madalina.merisescu@umfcd.ro",{"name":545,"email":546},"Monica Luminita Luminos","luminita.luminos@umfcd.ro",{"name":548,"email":549},"Carmen Pavelescu","carmen.pavelescu@rez.umfcd.ro",{"name":551,"email":552},"Jugulete Gheorghita","gheorghita.jugulete@umfcd.ro","2023-09-04","6NDYF0rWYbBywNc0fWBhIR_LM-Lo0aEBMAFDd6KOeJaQX28ooemMJIsFhCW0_w0QDBAOPogDoZkeVmCoY2uPfjYPtXdb7TwYkJdXuoKDwD7b6-BbOFODnZTsnBuzyNhRZGVeha45yhGc2HU6Pvu95Q",{"code":41,"msg":42,"data":556},{"rows":557,"total":643},[558,565,577,590,601,607,619,625,631,637],{"id":559,"is_public":6,"content":560,"username":561,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":563,"conflicts":50,"children":564},3890,"I really liked the article and its methodology, within the expected limitations due to only indirect access to patients in the control group.\r\n\r\nI have a question not entirely related to the article, but I think that it's worth an answer from one the authors.\r\n\r\nHow do you think the use of ''Ivermectin'' compares with the use of ''Hydroxychloroquine'', in the sense that it is even rarer that there are side effects with the use of ''Ivermectin''?\r\n\r\nWith ''Ivermectin'', it is possible that even patients with less risk could take it with litlle risk. \r\n\r\nWould it make sense to add zinc to those prescribed to use ''Ivermectin'' with ''Azithromycin'' or ''Doxicillin''?","Paulo Buchsbaum","/frontend/user/user_profile_image","2020-09-14 23:11:30",[],{"id":566,"is_public":6,"content":567,"username":162,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":568,"conflicts":50,"children":569},3841,"Thank you for all your comments. I am a family physician and not a researcher. I was not doing research, rather I was trying to keep my patients alive and out of the hospital. In early March, there was NO out-patient treatment recommended or even suggested. I was the FIRST in this country (perhaps even the world) to suggest and implement successful out-patient treatment of high risk patients. To suggest that the control group may of also received treatment is intellectually dishonest. At that time I was attacked from every direction and had no support from anyone. Thus, it is reasonable to assume that I was the ONLY one treating patients in this manner. \r\n\r\nRegarding selection bias of the control group: there was absolutely a bias but it was against me. I only treated high risk and patients (most of which were over the age 60) whereas the control group had both low and high risk patients. It is reasonable to assume that the average age of the control group was lower than the patients that I treated.","2020-09-06 03:49:36",[570],{"id":571,"is_public":6,"content":572,"email":573,"username":574,"affiliation":575,"user_avatar":562,"target_username":50,"target_comment_id":50,"target_user_id":50,"should_call_target":132,"user_id":50,"vote_num":41,"voted":132,"is_screener_report":132,"created_at":576,"conflicts":50},3944,"Dr Zev, I have followed what you have been doing, since March, when I was enthralled to hear you believed in something I had been hypothesising on: hydroxy chloroquine as a zinc ionosphere: and you were successfully using it in your community. \r\n\r\nYou have been up against obstacles and challenges, and your heartfelt aim was always to do good in your community.\r\n\r\nThis paper needs maybe to include some of your, and your colleagues, explanations, and be offered for peer review where possible, and get more publicity.\r\n\r\nA challenge has been that many patients treated in the community did not receive covid tests, and although they had all the symptoms of covid, they would not necessarily appear as a statistic, unless their situation worsened and they were admitted to hospital and tested. \r\n\r\nI know other community mds who have been treating \"obvious\" cases, who will, thank g~d, not be counted as covid cases because they were never sick enough for hospital, and never tested: they got better, thanks largely to hydroxychloroquine or quercetin and zinc and even vit C infusions etc.","mrae.tourmanager@gmail.com","Miryam Rae","Holistic therapist","2020-09-23 22:14:17",{"id":578,"is_public":6,"content":579,"username":580,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":581,"conflicts":50,"children":582},3813,"A huge congratulations and many thanks for sharing this information!\r\n\r\nSo, reading between the lines, we basically have highly effective prophylaxis treatment for COVID-19 comprised of just 3 OTC supplements:\r\n\r\n1. Elemental Zinc.\r\n2. Quercetin OR Epigallocatechin-gallate (EGCG) from Green Tea.\r\n3. Vitamin C.\r\n\r\nAll available in the local chemist without prescription and all perfectly safe and good for the health supplements regardless of COVID-19! \r\n\r\nI'm sure his excellency Dr. Zelenko would agree that the best way to reduce the pandemic as quickly and as safely as possible would be for as many adults as possible to take the above supplement combination for a period of time.\r\n\r\nOnce again, enormous gratitude!\r\nMF","Michael F.","2020-09-02 15:03:24",[583],{"id":584,"is_public":6,"content":585,"email":586,"username":587,"affiliation":588,"user_avatar":562,"target_username":50,"target_comment_id":50,"target_user_id":50,"should_call_target":132,"user_id":50,"vote_num":41,"voted":132,"is_screener_report":132,"created_at":589,"conflicts":50},3943,"Well done to dr zev and his colleagues. \r\nAn excellent paper and I have believed in the potential of hydroxychloroquine and zinc since March 2020. Hearing dr zev speak about it was encouraging. \r\n\r\nI would agree that quercetin has the same potential as hydroxychloroquine to act as ionophore to facilitate the zinc doing its job as antiviral, without potential side effects and available OTC\r\n\r\nWhy oh why are not all doctors /governments not recommending zinc, quercetin, vit D , (and arithromycin where bacterial infection is involved)???\r\nWhat can be done to make this happen?\r\n\r\nThe cynical side of me says it is because of big pharma and patents and vaccines, but that could never be true, as everyone involved in health care has taken an oath to look after our patients and that their wellbeing comes first before the cost of any drug or profits to be made.","pandora@mediauk.net","Pan dora","Background in complementary/chinese medicine","2020-09-23 21:59:17",{"id":591,"is_public":6,"content":592,"username":593,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":594,"conflicts":50,"children":595},3756,"I find it very disturbing that Zalenko repeatedly stated on his channel and in interviews that he treated hundreds -- well over 1000 -- patients for COVID, and that now all he can produce is a study that contains 104+37 patients. I no longer feel I can trust him. If the hundred of patients not included here never took a test to prove that they had the covid, then he should never have said he treated hundreds of patients who had covid! That is extraordinarily unethical. The president was making decisions based on feedback from doctors on the front line and him in particular. I feel he misled the president and the nation, and ppl like me who have been defending him at great cost to our reputation. Shame on him!","cg","2020-08-21 04:56:48",[596],{"id":597,"is_public":6,"content":598,"email":163,"username":162,"affiliation":599,"user_avatar":562,"target_username":50,"target_comment_id":50,"target_user_id":50,"should_call_target":132,"user_id":50,"vote_num":41,"voted":132,"is_screener_report":132,"created_at":600,"conflicts":50},3840,"Thank you for your comment. Let me clarify. My team saw 2200 Covid-19 patients from March to June. Out of those patients 800 were stratified has high risk and were treatment with my protocol. The 1400 low risk patients were treated with supportive care and they all recovered. Please understand that medical treatment doesn't always mean giving medication. Most of the time it is important to know when not to intervene and do no harm.\r\n\r\nOut of the 800 high risk patients only those that a positive PCR or IgG tests for Covid-19 were included in the study. The reason being that the medical community would not accept clinical diagnosis as valid proof of infection. That is how we arrived to the data set that was published. I hope that clarifies things for you.","Vladimir Zelenko MD PC","2020-09-06 03:27:22",{"id":602,"is_public":6,"content":603,"username":604,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":605,"conflicts":50,"children":606},3725,"This is an excellent article and I am very happy to see more and more studies underway to explore hydroxychloroquine, zinc, and azithromycin combo therapy for treating people with COVID-19. What baffles me is how much money and effort is being poured into fast-tracking novel, untested, and possibly expensive vaccines and how very little comparative effort and resources are being allocated to studies of this inexpensive and readily accessible alternative to vaccines. It appears that proponents of hydroxychloroquine are in an uphill battle to garner support for the use of this medication for COVID-19. A course of treatment for Remdesivir is $3500. The combo therapy of hydroxychloroquine, zinc, and azithromycin run less than $100. The bigger question to investigate would be “who has an investment in a vaccine solution (or expensive prescription antiviral medication) versus who stands to benefit from the hydroxychloroquine/zinc option.” Another question that might be raised is, why is there such tremendous resistance to the use of hydroxychloroquine? When faced with a life-threatening illness, who in their right mind would not employ what has been a safe, accessible, and inexpensive course of treatment for many decades?","Mr. Sabjo Rene’","2020-08-19 00:52:42",[],{"id":608,"is_public":6,"content":609,"username":610,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":611,"conflicts":50,"children":612},3710,"I am not in the public health. However, I have followed closely public the discussions by Dr. Zelenko in recent months. I have also followed the positive case and death counts on websites of my local counties. I presume one needs to make a request to the public health agencies of local counties through proper channel to examine the records. On Aug 11, I heard Dr. Zelenko say that his data is available for examination by anyone via legal means.\r\n\r\nThat said, I want to address this question on the demand for the gold standard RCT. First, I want to state that no experiments in physical sciences that I know of does any randomization for canceling of confounding factors or biases. In health sciences involving patients, to my knowledge the randomization is an efficient way for cancellation of biases and confounding factors. However, it is not clear to me that a placebo RCT can be performed on every segment of covid-19 patients and stages of illness. I cannot think that high risk patients can be given apart from the best of cares in light of available treatments. \r\n\r\nAbsent of an RCT study on high risk patients at the early stage of illness, here, I want emphasize that the paper's results of N=141 high risk patients is not insignificant. I am speaking not as a statistician. For background, I looked at the binomial distributions for mean frequency p=0.99 for cases N=10, 100 and 1,000. At 100, the peak is from 98 to 100. In other words, if one saw 99 patients of 100 survived, then when repeated the likely outcomes can be 98 to 100. The distribution allows for even lower numbers to 95 with very low probabilities. If patient count were 1,000, the distribution peak gets sharper and the results are even more solid. If non-randomized results are statistically solid, then any randomization in sampling (i.e. RCT) will not change outcomes.\r\n\r\nGranted that there can be confounding factors, we can look at what the possibilities are. Out of the 35,000 population in the community of one square mile [per Dr. Zelenko], assume the positive cases in the duration from Mar to May were of 10%, that is 3,500. \r\n\r\nall patients 335+37(10.6%) out of 3,500\r\nhigh risk 104+37(37.9%) out of 335+37\r\n\r\nIf we assume 40% to be the community wide number out of the 3,500, then there were 1,400 high risk patients. So, the number of high risk patients in the community is in the ball park of 1,500.\r\n\r\nIt is remarkable that Dr. Zelenko's clinic saw ~10% of the high risk patients in that time period early in the pandemic. Apart from the paper, Dr. Zelenko has frequently mentioned publicly of his team having seen ~2,200 covid-19 patients. And, the paper presents only 4(2.8%) out of 104+37 high risk patients got hospitalized compared to 58(15.4%) out of 377 in the community from public reference data. From this, the hospitalization rate is bracketed between 2.8% and 15.4%. Suppose, we form a binomial distribution for N=1,500 with mean frequency p=0.154 for hospitalization. At the 1,500, the peak is practically zero at below p=0.13 with the sum from p=0 to 0.13 giving only probability of 0.004. There is not much probability for below p=0.13 that is around p=0.028 and is almost zero from p=0 to 0.06, that is 1.4E-29 or 1.4x10^-29.\r\n\r\nHaving done this analysis, it appears to me that if the community hospitalization rate were 0.154 among high risk patients, the probability is zero for a local clinic to be seeing a rate of only 0.028 unless an external influence is present.","Kevin Lee","2020-08-16 09:08:48",[613],{"id":614,"is_public":6,"content":615,"email":616,"username":610,"affiliation":617,"user_avatar":562,"target_username":50,"target_comment_id":50,"target_user_id":50,"should_call_target":132,"user_id":50,"vote_num":41,"voted":132,"is_screener_report":132,"created_at":618,"conflicts":50},3745,"With further thoughts, the correct comparison in my previous posting towards the end should be to look at the N=141 as a subgroup to the N=1,500 community group. The correct analysis is to form the binomial distrubtion for N=141 subgroup with mean frequency p=0.154. This has a peak range from p=0.07 to 0.25. Then, we form a second distribution in order to see the range when it is centered at mean frequency p=0.028. It is from p=0 to 0.06. And, we sum values of the former distribution from p=0 to 0.06, to get an almost zero value, 9.1x10^-4. Statistically, this is the probability for to see the low hospitalization rate at Dr. Zelenko's clinic in my assumed scenario of mean community hospitalization rate of p=0.154 among high risk patients. It is different from the previous analysis but still is a small number.","klee200910@gmail.com","not employed","2020-08-20 09:27:18",{"id":620,"is_public":6,"content":621,"username":622,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":623,"conflicts":50,"children":624},3689,"Was strain typing performed? Could that be the reason behind the both the severity of disease and response to treatment? This in turn begs another question - could the severity of the disease confounded the patients' outcome in the study as Group A has both symptomatic and asymptomatic patients?","Zhou Da Jun","2020-08-12 05:58:15",[],{"id":626,"is_public":6,"content":627,"username":628,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":629,"conflicts":50,"children":630},3676,"The control group is a consecutive series of covid-19 patients, of all levels of severity. \r\n\r\nThe study patients should also be a consecutive series encountered by him, but it is not. During this study, Dr Zelenko doubtless had consultations with some patients reporting such urgent symptoms that he sent them directly to hospital for in-patient treatment, notably oxygen in some form. By excluding these severe cases, he has selected milder cases for treatment. Dr Zelenko's records are good, and he should give the number of sick patients he sent for immediate hospital care during the study period. If any of his patients went directly to hospital emergency departments on their own initiative, he would see them on discharge and/or get a summary letter from the hospital. Their number should also be given.","David Hamilton","2020-08-10 13:36:20",[],{"id":632,"is_public":6,"content":633,"username":634,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":635,"conflicts":50,"children":636},3645,"Excellent work! \r\nI'm a Computer Scientist, not a Physician, but a medical degree is not needed to discern what makes sense from what doesn't. \r\nFact: HQC has not provided a double-blind, randomized study.\r\nFact: Remdisivir can offer a double-blind, randomized study. \r\nBut here are some additional facts.\r\nFact: In the Ford Health System study of the effectiveness of the HQC protocol vis-a-vis Remdesivir, HQC showed better results than Remdesivir \r\nFact: Remdesivir has some significantly more long term adverse effects than the HQC protocol.\r\nhttps://www.drugs.com/sfx/remdesivir-side-effects.html\r\nFact: enough data is now available to unequivocally affirm that the death rate in countries that have been using the HQC protocol is 80% lower than those who have not. And the number of studies now available on the use of HQC is large and overwhelmingly supportive of Dr. Zelenko's claims.\r\nA compilation of them is available at\r\nhttps://c19study.com/\r\nIt is imperative that the FDA rescind all restrictions on the prescription and dispensation of HQC and allow it to be used at the discretion of physicians and patients.\r\nWe must take politics and financial gain out of a decision-making process that can save tens of thousands of lives in the coming months.","Jason W","2020-08-06 20:17:43",[],{"id":638,"is_public":6,"content":639,"username":640,"user_avatar":562,"user_id":50,"vote_num":41,"voted":132,"should_call_target":132,"is_screener_report":132,"created_at":641,"conflicts":50,"children":642},3635,"I read through the draft and saw no demographic information on the race of the treated patients vs. the control patients. Since race appears to be a significant risk factor, it might be wise to include that information. If the treated patients came from the Hasidic community where Dr. Zelenko practices, then there may be substantial racial differences between that set of patients and the broader community.","Mark H","2020-08-05 21:28:17",[],34,["Reactive",645],{"$scookieConsent":646,"$stoast-ui":647,"$ssite-config":649},{"necessary":6,"functional":132,"statistic":132,"marketing":132,"unclassified":132},{"showToast":132,"toastMessage":158,"toastVariant":648},"neutral",{"env":650,"name":651,"url":652},"production","nuxt-app","http://frontend.preprints.org/",["Set"],["ShallowReactive",655],{"NYU0sWvjqw":50,"mgOlEjP40X":50,"Ya7hZzqdE7":50,"pgtOJjaxbY":50,"JoG0wWOyMK":50,"i4W8kGDj4b":50},"/manuscript/202007.0025/v1",["Reactive",658],{"auth":659,"share-modal":661,"useHeader":662},{"userInfo":660,"isLogin":132},{},{"isShareModalOpen":132,"item":50},{"height":41}]</script> 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