CINXE.COM

Pathways and Diagrams | Cell Signaling Technology

<!-- DEBUG: contentId: shelf_10019004, contentType: contentCore, dataType: Page - https://www.cellsignal.com/test/contentItem.jsp?contentItemType=contentCore&contentId=shelf_10019004 --> <!DOCTYPE html> <html lang="en"> <head> <meta charset="UTF-8"> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta name="viewport" content="width=device-width, initial-scale=1, maximum-scale=1.0, user-scalable=no"> <meta name="theme-color" content="#235067"> <meta property="og:site_name" content="Cell Signaling Technology"> <meta name="keywords" content="pathways,cst pathways,cell signaling technology pathways"> <meta name="description" content="Pathways are grouped by research area and by disease area"> <meta name="contentfacet" value="contentCore"/> <meta name="formatfacet" value="Page"/> <meta name="contentId" value="shelf_10019004"/><meta name="robots" content="index,follow" /> <!-- metaDetails.jsp - title from param: Pathways and Diagrams --> <!-- metaDetails.jsp - SEOTags item with key: /common/content/content.jsp NOT FOUND. --> <title>Pathways and Diagrams | Cell Signaling Technology</title> <meta property="cst:page-title-analytics" content="Pathways and Diagrams | Cell Signaling Technology" class="OneLinkNoTx" /> <!-- Media --> <link rel="dns-prefetch" href="//media.cellsignal.com"> <!-- Google Analytics --> <link rel="dns-prefetch" href="//www.google-analytics.com"> <!-- Google Tag Manager --> <link rel="dns-prefetch" href="//www.googletagmanager.com"> <script type="text/javascript" src="/cst-client-js.jsp"></script> <script type="text/javascript" src="//media.cellsignal.com/www/dist/76.5.0/js/polyfills.min.js"></script> <!-- false && 0 --> <script> dataLayer = window.dataLayer || []; dataLayer.push({ 'atgId':'994774479', 'region': 'Other', 'countrySite': 'SG', 'pageType': 'pathways', 'topic': 'no topic', 'npi': 'no', 'userType': 'guest', 'loginStatus': '0', 'clientAddress':'8.222.208.146' }); </script> <script> function receiveMessage(event){ var authorized_iframes = ["https://cellsignal.tfaforms.net"]; if (authorized_iframes.indexOf(event.origin) > -1 && typeof event.data == "object"){ window.dataLayer = window.dataLayer || []; dataLayer.push(event.data); } return; } if (window.addEventListener) { window.addEventListener("message", receiveMessage, false); } else { window.attachEvent("onmessage", receiveMessage); } </script> <script> (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,'script','https://www.google-analytics.com/analytics.js','ga'); </script> <!-- Google Tag Manager --> <!-- First Container GTM--> <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-MNTN33CK');</script> <!-- Second Container GTM --> <!-- <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','');</script> --> <!-- End Google Tag Manager --> <!-- DEBUG host/port info - host from getHost.tag: https://www.cellsignal.com, requestURL: https://www.cellsignal.com/common/content/content.jsp, serverPort: 443, /cst/Configuration.siteName:www.cellsignal.com, servletPath: /common/content/content.jsp. --> <!-- DEBUG host/port info - host from getHost.tag: https://www.cellsignal.com, requestURL: https://www.cellsignal.com/common/content/content.jsp, serverPort: 443, /cst/Configuration.siteName:www.cellsignal.com, servletPath: /common/content/content.jsp. --> <link media="all" rel="canonical" href="https://www.cellsignal.com/pathways" /> <link rel="alternate" hreflang="en-US" href="https://www.cellsignal.com/pathways" /> <link rel="alternate" hreflang="zh-CN" href="https://www.cellsignal.cn/pathways"/> <link rel="alternate" hreflang="ja-JP" href="https://www.cellsignal.jp/pathways"/> <link rel="alternate" hreflang="en-JP" href="https://www.cellsignal.com/pathways"/> <link rel="alternate" hreflang="x-default" href="https://www.cellsignal.com/pathways" /> <link rel="icon" type="image/x-icon" href="/favicon.ico"> <link rel="stylesheet" href="//media.cellsignal.com/www/dist/76.5.0/css/vendor.min.css" /> <link rel="stylesheet" href="//media.cellsignal.com/www/dist/76.5.0/css/common.min.css" /> <link rel="stylesheet" href="//media.cellsignal.com/www/dist/76.5.0/css/template.min.css" /> <script type="text/javascript"> var bundle = new Object(); bundle["pdp.toPurchase.successMsg.itemAddedToShoppingList"] = 'Item has been added to list'; bundle["pdp.toPurchase.errorMsg.itemAlreadySavedToShoppingList"] = 'Item already saved to list'; </script></head> <body class="theme-navy" itemscope itemtype="http://schema.org/WebPage" data-template="content-page-tag" data-media-url="media.cellsignal.com"> <script type="text/javascript" src="//media.cellsignal.com/www/dist/76.5.0/js/bup.min.js"></script> <!-- Google Tag Manager (noscript) --> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-MNTN33CK" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <!-- End Google Tag Manager (noscript) --> <!-- HybridCutoverEnabled: true --> <!-- NetrexAccountCookiePresent: false --> <!-- IsCTEnabled: true --> <!-- ATG/CT userSecurityStatus: 0 --> <!-- ATG/CT isLoggedIn: false --> <!-- Netrex isLoggedInNetrex: false --> <!-- ct-customer: false --> <!-- ct-customer: --> <!-- CT Only isLoggedIn: false --> <input type="hidden" name="Ntk" value="Products" id="searchKey"/> <input type="hidden" name="Ntx" value="allany" id="matchMode"/> <input type="hidden" name="Nrpp" value="10" id="recordsPerPage"/> <!-- DEBUG-HEADER: SearchKey: Products, MatchMode: allany, RecordsPerPage: 10. --> <header data-session-conf="8232044757435438897" data-current-country="SG" data-userSecurityStatus="0" data-api-url="https://public-api.cellsignal.com/pclp2/v2" data-file-version="76.5.0" data-ispunchout='false' data-isb2d='true' data-isEnableBasketToQuote='false' data-media-url="media.cellsignal.com" data-signalStarEnabled="true" data-carrierSwitchUps="true"> <div id="navbar-top" class="de-navbar-top" > <div class="navbar-container" data-elastic-exclude> <!-- Menu-Holder-Country-Selector --> <button class="cc-btn" type="button" data-toggle="modal" id="changeCountryBtn" title="Change Country/Region"> <i class="cstf cstf-country-flag" aria-hidden="true"></i> <span class="currentCountryCode">SG</span> </button> <!-- Menu-Item-Phone-Number --> <div class="tech-support"> <a href="/learn-and-support/technical-support">Technical Support</a></div> <!-- Menu-Item --> <div class="contact-us"> <a href="/about-us/contact-us" target="_self" title="Go to Contact Us"> <i class="cstf cstf-contact-us" aria-hidden="true"></i> <span>Contact Us</span> </a> </div> <!-- Menu-Item-Social-Network --> <div class="phosphosite"> <a href="/learn-and-support/phosphositeplus-ptm-database" target="_blank" title="Go to PhosphoSitePlus"> <i class="cstf cstf-phosphosite" aria-hidden="true"></i> PhosphoSitePlus<sup>®</sup></a> </div> <div class="pull-right"> <div style="display: none"> <form submit="AccountPage.logUserOut()" method="post" name="logoutForm" action="/;jsessionid=1rqEEXhldyMB8XDE6dLxobETGccQoFeTjDRrxd_N.awsprod_store04?_DARGS=/include/header.jsp.logoutForm" id="logoutForm"><div style="display:none"><input name="_dyncharset" type="hidden" value="UTF-8"/> </div><div style="display:none"><input name="_dynSessConf" type="hidden" value="8232044757435438897"/> </div><input name="/atg/userprofiling/ProfileFormHandler.logoutSuccessURL" type="hidden" value="/"/><input name="_D:/atg/userprofiling/ProfileFormHandler.logoutSuccessURL" type="hidden" value=" "/><input name="/atg/userprofiling/ProfileFormHandler.logout" type="hidden" value="submit"/><input name="_D:/atg/userprofiling/ProfileFormHandler.logout" type="hidden" value=" "/><div style="display:none"><input name="_DARGS" type="hidden" value="/include/header.jsp.logoutForm"/> </div></form></div> <button type="button" class="qa-btn" data-toggle="popover" data-container="body" data-placement="bottom" data-html="true" data-popover-content="#popover-content"> <i class="fa fa-plus-circle" aria-hidden="true"></i> <b>Quick Add</b> </button> <div id="popover-content" class="hide"> <div class="popover-body"> <form> <div class="form-group"> <input id="quick-add-dialog-input-desktop" type="text" class="form-control" placeholder="Cat. No. (e.g. 4060S)" autocomplete="off" maxlength="7"> <div id="quick-add-dialog-alert-desktop" style="display: none" class="alert" role="alert">...</div> <button id="quick-add-dialog-button-desktop" type="button" class="btn btn-block btn-primary disabled" disabled>ADD TO BASKET</button> <a id="quick-add-dialog-link-desktop" href="/cart/quickAdd.jsp" class="btn btn-default btn-link btn-block">ADD MULTIPLE ITEMS</a> </div> </form> </div> </div> <a class="basket-link basket-button nav-btn cart-btn" href="javascript:void(0);" title="Basket"> <i class="cstf cstf-shopping-basket-hollow" aria-hidden="true"></i> <span id="basket-button"><b class="basket-text">Basket</b>(<span id="basket-items-count" class="basket-items-count" data-placement="bottom" title="Basket Updated" data-content="0">0</span>)</span> </a> </div> </div> </div> <div id="navbar-header"> <div class="navbar-container" data-elastic-exclude> <button class="menu-toggle" type="button" aria-expanded="false" aria-controls="navbar" aria-label="navigation menu toggle" title="Show Menu"> <span></span> <span></span> <span></span> <span></span> </button> <a class="brand" href="/" title="Go to homepage"> <img src="https://media.cellsignal.com/www/images/global/cst-logo-blue.svg" alt="Cell Signaling Technology" /> </a> <button type="button" class="nav-btn quick-add-btn" data-toggle="popover" data-container="body" data-placement="bottom" data-html="true" data-popover-content="#popover-content"> <i class="cstf cstf-combined-shape" aria-hidden="true"></i> </button> <div id="popover-content" class="hide"> <div class="popover-body"> <form> <div class="form-group"> <input id="quick-add-dialog-input-mobile" type="text" class="form-control" placeholder="Cat. No. (e.g. 4060S)"> <div id="quick-add-dialog-alert-mobile" style="display: none" class="alert" role="alert">...</div> <button id="quick-add-dialog-button-mobile" type="button" class="btn btn-block btn-primary">ADD TO BASKET</button> <a id="quick-add-dialog-link-mobile" href="/cart/quickAdd.jsp" class="btn btn-default btn-link btn-block">ADD MULTIPLE ITEMS</a> </div> </form> </div> </div> <a class="basket-button nav-btn" href="#" title="Basket"> <i class="cstf cstf-shopping-basket" aria-hidden="true"></i> <span id="basket-button-mobile"><span id="basket-items-count-mobile" class="basket-items-count" data-placement="bottom" title="Basket Updated" data-content="0">0</span></span> </a> <button id="search-mobile" class="search-btn" type="button" aria-label="search" title="toggle search bar"> <span><i class="cstf cstf-search" aria-hidden="true"></i></span> </button> </div> </div> <div id="cstGlobalPromotion"> <a data-creative="purple banner" data-title="ROW: CST Promotions" href="/contents/products/promotions-coupons-for-cell-signaling-technology/promotions/" title="CST Promotions">View Featured Offers &gt;&gt;</a></div> <div id="main-nav" aria-hidden="true"> <div class="navbar-container" data-elastic-exclude> <a class="brand" href="/" title="Go to homepage"> <img src="https://media.cellsignal.com/www/images/global/cst-logo-blue.svg" alt="Cell Signaling Technology" /> </a> <div class="menu-top"> <button class="menu-toggle open" type="button" aria-expanded="true" aria-controls="navbar" aria-label="close navigation menu" title="Close Menu"> <i class="cstf cstf-close" aria-hidden="true"></i> </button> </div> <nav aria-label="Main Navigation"> <!-- menu - bcc --> <div id="mainLinks" class="primary-menu"> <ul> <li class="active"><a href="/" title="Home">Home</a></li> <!-- Menu-Holder-Product --> <li data-menu="Products"> <a href="/browse/" title="Go to Products sub menu" data-en-label="Products"><span>Products</span></a> <div class="sub-menu-border"></div> <div id="ProductsLinks" class="row sub-menu"> <div class="col-xs-12 menu-back-btn"> <button type="button" aria-label="Back to Main Menu" title="Back to Main Menu"> <i class="cstf cstf-angle-left" aria-hidden="true"></i> </button> </div> <ul> <li class="menu-parent"><a href="/browse/" title="Go to Products" data-en-label="Products">Products</a></li> </ul> <!-- FIXME: Revert this change back when reverting RA --> <div class="col-md-12"> <div class="nav-heading">Filtered by Product Category</div> <div class="row"> <ul class="col-md-6"> <li> <a href="/browse?other=newproduct&sortby=Newest" title="Go to New Products">New Products</a> </li> <li> <a href="/browse?categories=Primary%20Antibodies" title="Go to Primary Antibodies">Primary Antibodies</a> </li> <li> <a href="/browse?categories=Secondary%20Antibodies" title="Go to Secondary Antibodies">Secondary Antibodies</a> </li> <li> <a href="/browse?producttype=Antibody%20Sampler%20Kit" title="Go to Antibody Samplers">Antibody Samplers</a> </li> <li> <a href="/browse?categories=Antibody%20Conjugates" title="Go to Antibody Conjugates">Antibody Conjugates</a> </li> <li> <a href="/browse?categories=ELISA%20Kits" title="Go to ELISA Kits">ELISA Kits</a> </li> <li> <a href="/browse?categories=Cellular%20Assay%20Kits" title="Go to Cellular Assay Kits">Cellular Assay Kits</a> </li> <li> <a href="/browse?categories=Proteomic%20Analysis%20Products" title="Go to Proteomic Analysis Products">Proteomic Analysis Products</a> </li> <li> <a href="/browse?categories=WB%20%26%20IP%20Reagents" title="Go to WB & IP Reagents">WB & IP Reagents</a> </li> <li> <a href="/browse?tab=product&categories=SignalStar%26%238482%3B%20Multiplex%20IHC%20Kits%20%26%20Reagents" title="Go to SignalStar™ Multiplex IHC Kits & Reagents">SignalStar™ Multiplex IHC Kits & Reagents</a> </li> </ul> <ul class="col-md-6"> <li> <a href="/browse?tab=product&search=InTraSeq&redirect=true" title="Go to InTraSeq™ Kit & Reagents">InTraSeq™ Kit & Reagents</a> </li> <li> <a href="/browse?categories=CUT%26RUN%20Kits%20%26%20Reagents" title="Go to CUT&RUN Kits & Reagents">CUT&RUN Kits & Reagents</a> </li> <li> <a href="/browse?tab=product&applications=CUT%26Tag&noscroll=1" title="Go to CUT&Tag Kits & Reagents">CUT&Tag Kits & Reagents</a> </li> <li> <a href="/browse?categories=ChIP%20Kits%20%26%20Reagents" title="Go to ChIP Kits & Reagents">ChIP Kits & Reagents</a> </li> <li> <a href="/browse?categories=Flow%20Cytometry%20Kits%20%26%20Reagents" title="Go to Flow Cytometry Kits & Reagents">Flow Cytometry Kits & Reagents</a> </li> <li> <a href="/browse?categories=Recombinant%20Proteins" title="Go to Recombinant Proteins">Recombinant Proteins</a> </li> <li> <a href="/browse?categories=siRNA" title="Go to siRNA">siRNA</a> </li> <li> <a href="/browse?categories=Cytokines%20%26%20Growth%20Factors" title="Go to Cytokines & Growth Factors">Cytokines & Growth Factors</a> </li> <li> <a href="/browse?categories=Activators%20%26%20Inhibitors" title="Go to Activators & Inhibitors">Activators & Inhibitors</a> </li> <li> <a href="/browse?categories=Buffers%20%26%20Dyes" title="Go to Buffers & Dyes">Buffers & Dyes</a> </li> <li> <a href="/browse?formulation=BSA%20and%20Azide%20Free" title="Go to BSA and Azide Free">BSA and Azide Free</a> </li> </ul> </div> </div> </div> </li> <!-- Menu-Holder-One-Column --> <li data-menu="Applications"> <a href="/applications" title="Go to Applications sub menu" data-en-label="Applications"><span>Applications</span></a> <div class="sub-menu-border"></div> <div id="ApplicationsLinks" class="row sub-menu"> <div class="col-xs-12 menu-back-btn"> <button type="button" aria-label="Back to Main Menu" title="Back to Main Menu"> <i class="cstf cstf-angle-left" aria-hidden="true"></i> </button> </div> <ul> <li class="menu-parent"><a href="/applications" title="Go to Applications" data-en-label="Applications">Applications</a></li> <div class="nav-heading">Resource Centers</div> <li> <a href="/applications/chip-and-chip-seq" target="_self" title="Go to ChIP & ChIP-seq" data-en-label="ChIP & ChIP-seq">ChIP & ChIP-seq</a> </li> <li> <a href="/applications/cut-and-run" target="_self" title="Go to CUT&RUN" data-en-label="CUT&RUN">CUT&RUN</a> </li> <li> <a href="/applications/cut-tag" target="_self" title="Go to CUT&Tag" data-en-label="CUT&Tag">CUT&Tag</a> </li> <li> <a href="/applications/elisa" target="_self" title="Go to ELISA" data-en-label="ELISA">ELISA</a> </li> <li> <a href="/applications/flow-cytometry" target="_self" title="Go to Flow Cytometry" data-en-label="Flow Cytometry">Flow Cytometry</a> </li> <li> <a href="/applications/immunofluorescence" target="_self" title="Go to Immunofluorescence" data-en-label="Immunofluorescence">Immunofluorescence</a> </li> <li> <a href="/applications/immunohistochemistry" target="_self" title="Go to Immunohistochemistry" data-en-label="Immunohistochemistry">Immunohistochemistry</a> </li> <li> <a href="/applications/immunoprecipitation" target="_self" title="Go to Immunoprecipitation" data-en-label="Immunoprecipitation">Immunoprecipitation</a> </li> <li> <a href="/applications/intraseq-single-cell" target="_self" title="Go to InTraSeq™ Single Cell Analysis" data-en-label="InTraSeq™ Single Cell Analysis">InTraSeq™ Single Cell Analysis</a> </li> <li> <a href="/applications/proteomics" target="_self" title="Go to LC/MS Proteomics" data-en-label="LC/MS Proteomics">LC/MS Proteomics</a> </li> <li> <a href="/applications/multiplexing-and-spatial-biology" target="_self" title="Go to Multiplexing and Spatial Biology" data-en-label="Multiplexing and Spatial Biology">Multiplexing and Spatial Biology</a> </li> <li> <a href="/applications/signalstar-multiplex-ihc" target="_self" title="Go to SignalStar™ Multiplex IHC" data-en-label="SignalStar™ Multiplex IHC">SignalStar™ Multiplex IHC</a> </li> <li> <a href="/applications/western-blot-immunoblot" target="_self" title="Go to Western Blot (Immunoblot)" data-en-label="Western Blot (Immunoblot)">Western Blot (Immunoblot)</a> </li> </ul> </div> </li> <!-- Menu-Holder-One-Column --> <li data-menu="Research"> <a href="/research" title="Go to Research sub menu" data-en-label="Research"><span>Research</span></a> <div class="sub-menu-border"></div> <div id="ResearchLinks" class="row sub-menu"> <div class="col-xs-12 menu-back-btn"> <button type="button" aria-label="Back to Main Menu" title="Back to Main Menu"> <i class="cstf cstf-angle-left" aria-hidden="true"></i> </button> </div> <ul> <li class="menu-parent"><a href="/research" title="Go to Research" data-en-label="Research">Research</a></li> <li> <a href="/research/cancer" target="_self" title="Go to Cancer" data-en-label="Cancer">Cancer</a> </li> <li> <a href="/research/cell-biology" target="_self" title="Go to Cell Biology" data-en-label="Cell Biology">Cell Biology</a> </li> <li> <a href="/research/developmental-biology-and-stem-cells" target="_self" title="Go to Developmental Biology and Stem Cells" data-en-label="Developmental Biology and Stem Cells">Developmental Biology and Stem Cells</a> </li> <li> <a href="/research/drug-discovery-solutions-powered-by-cst" target="_self" title="Go to Drug Discovery Solutions Powered by CST" data-en-label="Drug Discovery Solutions Powered by CST">Drug Discovery Solutions Powered by CST</a> </li> <li> <a href="/research/epigenetics" target="_self" title="Go to Epigenetics" data-en-label="Epigenetics">Epigenetics</a> </li> <li> <a href="/research/fibrosis" target="_self" title="Go to Fibrosis" data-en-label="Fibrosis">Fibrosis</a> </li> <li> <a href="/research/immunology-and-immuno-oncology" target="_self" title="Go to Immunology and Immuno-Oncology" data-en-label="Immunology and Immuno-Oncology">Immunology and Immuno-Oncology</a> </li> <li> <a href="/research/infectious-diseases-covid-19" target="_self" title="Go to Infectious Diseases / COVID-19" data-en-label="Infectious Diseases / COVID-19">Infectious Diseases / COVID-19</a> </li> <li> <a href="/research/metabolism" target="_self" title="Go to Metabolism" data-en-label="Metabolism">Metabolism</a> </li> <li> <a href="/research/neuroscience" target="_self" title="Go to Neuroscience" data-en-label="Neuroscience">Neuroscience</a> </li> <li> <a href="/research/rna-regulation-and-translational-control" target="_self" title="Go to RNA Regulation and Translational Control" data-en-label="RNA Regulation and Translational Control">RNA Regulation and Translational Control</a> </li> </ul> </div> </li> <!-- Menu-Holder-One-Column --> <li data-menu="Pathways"> <a href="/pathways" title="Go to Pathways sub menu" data-en-label="Pathways"><span>Pathways</span></a> <div class="sub-menu-border"></div> <div id="PathwaysLinks" class="row sub-menu"> <div class="col-xs-12 menu-back-btn"> <button type="button" aria-label="Back to Main Menu" title="Back to Main Menu"> <i class="cstf cstf-angle-left" aria-hidden="true"></i> </button> </div> <ul> <li class="menu-parent"><a href="/pathways" title="Go to Pathways" data-en-label="Pathways">Pathways</a></li> <li> <a href="/pathways/by-disease-area" target="_self" title="Go to By Disease Area" data-en-label="By Disease Area">By Disease Area</a> </li> <li> <a href="/pathways/by-research-area" target="_self" title="Go to By Research Area" data-en-label="By Research Area">By Research Area</a> </li> <li> <a href="/pathways/cellular-landscapes" target="_self" title="Go to Cellular Landscapes" data-en-label="Cellular Landscapes">Cellular Landscapes</a> </li> </ul> </div> </li> <!-- Menu-Holder-One-Column --> <li data-menu="Services"> <a href="/services" title="Go to Services sub menu" data-en-label="Services"><span>Services</span></a> <div class="sub-menu-border"></div> <div id="ServicesLinks" class="row sub-menu"> <div class="col-xs-12 menu-back-btn"> <button type="button" aria-label="Back to Main Menu" title="Back to Main Menu"> <i class="cstf cstf-angle-left" aria-hidden="true"></i> </button> </div> <ul> <li class="menu-parent"><a href="/services" title="Go to Services" data-en-label="Services">Services</a></li> <li> <a href="/services/customized-and-carrier-free-formulation" target="_self" title="Go to Carrier-Free Custom Antibody Formulations" data-en-label="Carrier-Free Custom Antibody Formulations">Carrier-Free Custom Antibody Formulations</a> </li> <li> <a href="/services/custom-peptides" target="_self" title="Go to AQUA and Custom Blocking Peptides" data-en-label="AQUA and Custom Blocking Peptides">AQUA and Custom Blocking Peptides</a> </li> <li> <a href="/services/proteomics-analytical-services" target="_self" title="Go to Proteomics Analytical Services" data-en-label="Proteomics Analytical Services">Proteomics Analytical Services</a> </li> <li> <a href="/services/custom-conjugation-services" target="_self" title="Go to Custom Conjugation & Labeling Services" data-en-label="Custom Conjugation & Labeling Services">Custom Conjugation & Labeling Services</a> </li> <li> <a href="/services/bulk-quantities-and-lot-reservations" target="_self" title="Go to Bulk Quantities and Lot Reservations" data-en-label="Bulk Quantities and Lot Reservations">Bulk Quantities and Lot Reservations</a> </li> </ul> </div> </li> <!-- Menu-Holder-Two-Column --> <li data-menu="LearnSupport"> <a href="/learn-and-support" title="Go to Learn & Support sub menu" data-en-label="Learn & Support"><span>Learn & Support</span></a> <div class="sub-menu-border"></div> <div id="LearnSupportLinks" class="row sub-menu"> <div class="col-xs-12 menu-back-btn"> <button type="button" aria-label="Back to Main Menu" title="Back to Main Menu"> <i class="cstf cstf-angle-left" aria-hidden="true"></i> </button> </div> <ul> <li class="menu-parent"><a href="/learn-and-support" title="Go to Learn & Support" data-en-label="Learn & Support">Learn & Support</a></li> </ul> <div class="col-md-8"> <div class="nav-heading">Education & Resources</div> <div class="row"> <ul class="col-md-6"> <li> <a href="/learn-and-support/antibody-conjugates" title="Go to Antibody Conjugates" data-en-label="Antibody Conjugates">Antibody Conjugates</a> </li> <li> <a href="https://blog.cellsignal.com/" title="Go to Blog" data-en-label="Blog">Blog</a> </li> <li> <a href="/learn-and-support/conferences-and-events" title="Go to Conferences & Events" data-en-label="Conferences & Events">Conferences & Events</a> </li> <li> <a href="/learn-and-support/control-treatments-by-target" title="Go to Control Treatments by Target" data-en-label="Control Treatments by Target">Control Treatments by Target</a> </li> <li> <a href="/learn-and-support/pdf-download-page" title="Go to Downloadable Literature" data-en-label="Downloadable Literature">Downloadable Literature</a> </li> <li> <a href="/learn-and-support/phosphositeplus-ptm-database" title="Go to PhosphoSitePlus® PTM Database" data-en-label="PhosphoSitePlus® PTM Database">PhosphoSitePlus® PTM Database</a> </li> </ul> <ul class="col-md-6"> <li> <a href="/learn-and-support/protein-domains-and-interactions" title="Go to Protein Domains & Interactions" data-en-label="Protein Domains & Interactions">Protein Domains & Interactions</a> </li> <li> <a href="/learn-and-support/protein-kinases" title="Go to Protein Kinases" data-en-label="Protein Kinases">Protein Kinases</a> </li> <li> <a href="/learn-and-support/publications-and-posters" title="Go to Publications & Research Posters" data-en-label="Publications & Research Posters">Publications & Research Posters</a> </li> <li> <a href="/learn-and-support/reference-tables" title="Go to Reference Tables" data-en-label="Reference Tables">Reference Tables</a> </li> <li> <a href="/learn-and-support/scientific-web-resources" title="Go to Scientific Web Resources" data-en-label="Scientific Web Resources">Scientific Web Resources</a> </li> <li> <a href="/learn-and-support/videos-and-webinars" title="Go to Videos & Webinars" data-en-label="Videos & Webinars">Videos & Webinars</a> </li> </ul> </div> </div> <!-- [oneColumnMenuHolder:5400020] --> <div class="col-md-4"> <div class="nav-heading">Troubleshooting & Support</div> <div class="row"> <ul class="col-md-12"> <li> <a href="/learn-and-support/technical-support" title="Go to Technical Support" data-en-label="Technical Support">Technical Support</a> </li> <li> <a href="/learn-and-support/support-information" title="Go to Contact Support" data-en-label="Contact Support">Contact Support</a> </li> <li> <a href="/learn-and-support/troubleshooting" title="Go to Troubleshooting" data-en-label="Troubleshooting">Troubleshooting</a> </li> <li> <a href="/learn-and-support/protocols" title="Go to Protocols" data-en-label="Protocols">Protocols</a> </li> <li> <a href="/learn-and-support/technical-documentation" title="Go to Technical Documentation" data-en-label="Technical Documentation">Technical Documentation</a> </li> </ul> </div> </div> </div> </li> <!-- Menu-Holder-One-Column --> <li data-menu="AboutUs"> <a href="/about-us" title="Go to About Us sub menu" data-en-label="About Us"><span>About Us</span></a> <div class="sub-menu-border"></div> <div id="AboutUsLinks" class="row sub-menu"> <div class="col-xs-12 menu-back-btn"> <button type="button" aria-label="Back to Main Menu" title="Back to Main Menu"> <i class="cstf cstf-angle-left" aria-hidden="true"></i> </button> </div> <ul> <li class="menu-parent"><a href="/about-us" title="Go to About Us" data-en-label="About Us">About Us</a></li> <li> <a href="/about-us/our-company" target="_self" title="Go to Our Company" data-en-label="Our Company">Our Company</a> </li> <li> <a href="/about-us/our-approach-process" target="_self" title="Go to Our Approach/Process" data-en-label="Our Approach/Process">Our Approach/Process</a> </li> <li> <a href="/about-us/cst-antibody-validation-principles" target="_self" title="Go to Product Performance & Validation" data-en-label="Product Performance & Validation">Product Performance & Validation</a> </li> <li> <a href="/about-us/environmental-and-social-responsibility" target="_self" title="Go to Environmental & Social Responsibility" data-en-label="Environmental & Social Responsibility">Environmental & Social Responsibility</a> </li> <li> <a href="https://careers.cellsignal.com/" target="_self" title="Go to Careers" data-en-label="Careers">Careers</a> </li> <li> <a href="/about-us/partnerships-and-licensing" target="_self" title="Go to Partnerships & Licensing" data-en-label="Partnerships & Licensing">Partnerships & Licensing</a> </li> <li> <a href="/about-us/contact-us" target="_self" title="Go to Contact Us" data-en-label="Contact Us">Contact Us</a> </li> </ul> </div> </li> </ul> </div> <!-- /menu - bcc --> <div class="menu-bottom"> <ul aria-label="Helpful Links"> <!-- Menu-Holder-Country-Selector --> <!-- Current/Change Country Selector --> <li> <button class="cc-btn" type="button" data-toggle="modal" id="changeCountryMenuBtn" title="Change Country/Region"> <i class="cstf cstf-country-flag" aria-hidden="true"></i> <span class="currentCountryCode">Country/Region: SG</span> </button> </li> <!-- Menu-Item-Phone-Number --> <li class="tech-support"> <a href="/learn-and-support/technical-support">Technical Support</a></li> <!-- Menu-Item --> <!-- Contact Us --> <li> <a href="/about-us/contact-us" target="_self" title="Go to Contact Us"> <i class="cstf cstf-contact-us" aria-hidden="true"></i> Contact Us</a> </li> <!-- Menu-Item-Social-Network --> <li> <a class="phosphosite" href="/learn-and-support/phosphositeplus-ptm-database" target="_blank" title="Go to PhosphoSitePlus"> <i class="cstf cstf-phosphosite" aria-hidden="true"></i> PhosphoSitePlus<sup>®</sup></a> </li> </ul> </div> </nav> </div> </div> <div id="navbar-search"> <div class="search-flex-wrapper"> <!-- Implementing flex wrapper gives abilitty to insert anythin without breaking style --> <form class="form-search" action="/browse/" method="get" onsubmit="return GlobalSearch.submit(this);" id="globalKeywordSearchForm" aria-label="Product Site Search"> <!--<input type="search" id="site-search" name="site-search" value="" placeholder="Search keyword or product #" />--> <input type="hidden" name="Ntk" id="hdnSearchScope" value="Products"> <input type="hidden" name="N" id="hdnSearchScopeN" value="4294956287"> <input type="search" id="global_search_keyword" name="Ntt" value="" placeholder="Search by keyword or product number" onkeyup="FormControlUtils.checkInput($('.keywordSearchBtn'), $(this), true);" autocomplete="off"> <ul class="typeahead dropdown-menu"></ul> <input type="hidden" disabled="disabled" value="" id="global_search_carry_over_content" name="content"> <button class="btn global-search-btn disabled keywordSearchBtn" disabled type="submit" aria-label="search" title="search"> <i class="cstf cstf-search"></i> </button> <div class="select-wrapper hidden"> <select id="site-search-type" name="site-search-type"> <option value="Products" data-code="4294956287">Products</option> <option value="Content" data-code="4294956305">Content</option> </select> <i class="cstf cstf-chevron-down" aria-hidden="true"></i> </div> </form> </div> </div> <div class="shield"></div> </header> <main class="container-fluid "> <span class="hide" id="data-helper" data-page-id="pathways" data-media-url="media.cellsignal.com" data-file-version="76.5.0"></span> <div><!-- start content cartridge "content-slot" --> <!-- DEBUG: TemplateCategory.jsp --> <div class="row"> <div class="col-xs-12"> <!-- contentCore:shelf_10019004 --> <!-- Otherwise --> <div class="hide" data-NOLOG="TRUE"></div> <nav data-template="content-breadcrumb-block"> <ol class="breadcrumb"> <li> <a href="/" class="link-inverse">Home</a></li> <li>Pathways and Diagrams</li> </ol> </nav> <div data-template="content-page-header"> <h1>Pathways and Diagrams</h1> </div> </div> </div> <div class="row" data-template="category"> <div class="col-md-4 col-md-push-8"> <div data-template="content-subcategory-list" data-elastic-exclude> <ul class="subcategory-links"> <li><a href="/pathways/by-disease-area">By Disease Area</a></li> <li><a href="/pathways/by-research-area">By Research Area</a></li> <li><a href="/pathways/cellular-landscapes">Cellular Landscapes</a></li> </ul> </div> <div class="subCatLinksNav" data-elastic-exclude> <p>Choose a Pathways and Diagrams Sub-category:</p> <select onchange="location.href = this.value;"> <option disabled="" selected="" value="">-Select Pathways and Diagrams-</option> <option value="/pathways/by-disease-area">By Disease Area</option> <option value="/pathways/by-research-area">By Research Area</option> <option value="/pathways/cellular-landscapes">Cellular Landscapes</option> </select> </div> </div> <div class="col-md-8 col-md-pull-4"> <div data-template="content-html-block"> <img alt="Pathways" class="img-responsive" src="https://media.cellsignal.com/www/images/pathways/pathways-144-px.jpg" /></p> <p class="p-empty extra-top-spacing">Quickly identify your next research target using the interactive pathways, diagrams, guides and cellular landscapes in each of these collections. These resources provide insights into relevant cellular processes, structures and related diseases to help you identify related proteins and cellular mechanisms to investigate in your research. Each collection has been developed and curated by CST scientists and outside experts to provide current and useful tools to aid your particular area of research.<div class="showMoreWrapper"> <a id="showMoreButton" class="showMoreButtonHidden" data-toggle="contentHtmlBlockModal" onclick="showMoreModal('content')" data-toggle="modal">Show More</a> </div> </div> </div> </div> <div class="row"> <div class="col-xs-12"> </div> </div> <!-- end content cartridge "content-slot" --> </div></main> <footer class="container-fluid" data-elastic-exclude> <div class="top-footer-background-wrapper"> <!-- Footer Navigation --> <!-- Top Footer --> <nav class="row top-footer"> <!-- firstColumnItems --> <div class="col-sm-3 footer-menu-column"> <div class="collapsible footer-menu-holder"> <h4><span>About Us</span></h4> <ul> <li><a href="/about-us/our-company" title="Link to find out more about Our Company" target="_self">Our Company</a> </li> <li><a href="/about-us/our-approach-process" title="Link to find out more about Our Approach/Process" target="_self">Our Approach/Process</a> </li> <li><a href="/about-us/our-approach-process/cst-antibody-performance-guarantee" title="Link to find out more about Product Performance Guarantee" target="_self">Product Performance Guarantee</a> </li> <li><a href="https://careers.cellsignal.com/" title="Link to find out more about Careers" target="_self">Careers</a> </li> <li><a href="/about-us/environmental-and-social-responsibility" title="Link to find out more about Environmental & Social Responsibility" target="_self">Environmental & Social Responsibility</a> </li> <li><a href="https://learn.cellsignal.com/newsletter-sign-up" title="Link to find out more about Sign Up for News" target="_self">Sign Up for News</a> </li> </ul> </div> </div> <!-- secondColumnItems --> <div class="col-sm-3 footer-menu-column"> <div class="collapsible footer-menu-holder"> <h4><span>Resources</span></h4> <ul> <li> <a href="/learn-and-support" title="Link to find out more about Learn & Support">Learn & Support</a> </li> <li> <a href="/learn-and-support/protocols" title="Link to find out more about Protocols">Protocols</a> </li> <li> <a href="/pathways" title="Link to find out more about Pathways">Pathways</a> </li> <li> <a href="https://blog.cellsignal.com/" title="Link to find out more about Blog">Blog</a> </li> <li> <a href="/learn-and-support/conferences-and-events" title="Link to find out more about Conferences & Events">Conferences & Events</a> </li> <li> <a href="/learn-and-support/phosphositeplus-ptm-database" title="Link to find out more about Protein Modification Resource">Protein Modification Resource</a> </li> <li> <a href="/learn-and-support/videos-and-webinars" title="Link to find out more about Videos & Webinars">Videos & Webinars</a> </li> </ul> </div> </div> <!-- thirdColumnItems --> <div class="col-sm-3 footer-menu-column"> <div class="collapsible footer-menu-holder"> <h4><span>Legal</span></h4> <ul> <li><a href="/legal/trademark-information" title="Link to find out more about Trademark Info" target="_self">Trademark Info</a> </li> <li><a href="/legal/privacy/privacy-policy" title="Link to find out more about Privacy Policy" target="_self">Privacy Policy</a> </li> <li><a href="/legal/privacy/cookie-policy" title="Link to find out more about Cookie Policy" target="_self">Cookie Policy</a> </li> <li><a href="/legal/terms-and-conditions" title="Link to find out more about Terms & Conditions" target="_self">Terms & Conditions</a> </li> </ul> </div> </div> <!-- fourthColumnItems --> <div class="col-sm-3 footer-menu-column"> <div class="collapsible footer-menu-holder"> <h4><span>Help &amp; Support</span></h4> <ul> <li> <a href="/learn-and-support/technical-support">Technical Support</a></li> <li> <a href="/learn-and-support/support-information" title="Link to find out more about Contact Support" target="_self">Contact Support</a> </li> <li> <a href="/about-us/contact-us" title="Link to find out more about Contact Us" target="_self">Contact Us</a> </li> <li> <a href="/learn-and-support/frequently-asked-questions" title="Link to find out more about FAQs" target="_self">FAQs</a> </li> </ul> <!-- false :: false :: false --> </div> <!-- Social Area --> <!-- firstColumnItems --> <div class="col-xs-12 social"> <ul class="social-links"> <!-- Facebook --> <li> <a class="facebook" href="https://www.facebook.com/cellsignal" target="_blank" title="Facebook for Cell Signaling Technology" aria-label="Facebook link"> <i class="cstf cstf-facebook" aria-hidden="true"></i> </a> </li> <!-- Twitter --> <li> <a class="twitter" href="https://twitter.com/cellsignal" target="_blank" title="Twitter for Cell Signaling Technology" aria-label="Twitter link"> <i class="cstf cstf-twitter" aria-hidden="true"></i> </a> </li> <!-- LinkedIn --> <li> <a class="linkedin" href="https://www.linkedin.com/company/cell-signaling-technology" target="_blank" title="LinkedIn for Cell Signaling Technology" aria-label="LinkedIn link"> <i class="cstf cstf-linkedin" aria-hidden="true"></i> </a> </li> <!-- Instagram --> <li> <a class="instagram" href="https://www.instagram.com/cell_signaling_technology" target="_blank" title="Instagram for Cell Signaling Technology" aria-label="Instagram link"> <i class="cstf cstf-instagram" aria-hidden="true"></i> </a> </li> <!-- YouTube --> <li> <a class="youtube" href="https://www.youtube.com/user/cellsignaldotcom" target="_blank" title="YouTube for Cell Signaling Technology" aria-label="YouTube link"> <i class="cstf cstf-youtube" aria-hidden="true"></i> </a> </li> </ul> </div> </div> </nav> </div> <div class="row bottom-footer"> <!-- Bottom Footer --> <div class="col-xs-12 bottom-footer-wrapper"> <div class="col-sm-9"> <!-- Copyright --> <!-- firstColumnItems --> <div class="copyright"> <small> For Research Use Only. Not for Use in Diagnostic Procedures.<br/> &copy; Sun Nov 24 01:31:19 EST 2024 &nbsp;Cell Signaling Technology, Inc. All Rights Reserved.</small> </div> <!-- We Chat --> </div> <!-- Footer Logo --> <div class="hidden-xs col-sm-3"> <a class="brand" href="/" title="Go to homepage"> <img src="https://media.cellsignal.com/www/images/global/cst-logo-white.svg" alt="Cell Signaling Technology" class="img-responsive footer-logo" /> </a> </div> </div> </div> </footer> <!-- Footer Additions --> <!-- Modals --> <div class="country-selector modal fade" id="changeCountryModal" tabindex="-1" role="dialog" aria-labelledby="myModalLabel"> <div class="modal-dialog modal-sm" role="document"> <div class="modal-content"> <div class="modal-header"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">&times;</span></button> <h2 class="modal-title" id="myModalLabel">Select your country/region</h2> </div> <div class="modal-body"> <form onsubmit="return CountrySelector.shadowSubmit($('#updateCountryForm'), $('#newCountryCode'));"> <div class="country-selector-wrap"> <label for="country-selector-input">Country/Region</label> <input type="text" name="country-selector-input" id="country-selector-input" placeholder="Enter Country/Region or Code" value="" autocomplete="off"> <div id="country-selector"> <select class="hide"> <option value="SINGAPORE" data-id="SG" ></option> </select> </div> </div> </form> </div> <div class="modal-footer"> <button type="button" id="country-selector-button" class="btn btn-primary" data-dismiss="modal" onclick="return CountrySelector.shadowSubmit($('#updateCountryForm'), $('#newCountryCode'));">Continue</button> <!--<button type="button" class="btn btn-primary">Continue</button>--> </div> </div> </div> </div> <div style="display: none;"> <form method="post" action="/ajax/profile/updateCountry.jsp;jsessionid=1rqEEXhldyMB8XDE6dLxobETGccQoFeTjDRrxd_N.awsprod_store04?_DARGS=/include/popup/Country-Selector-Modal.jsp.updateCountryForm" id="updateCountryForm"><div style="display:none"><input name="_dyncharset" type="hidden" value="UTF-8"/> </div><div style="display:none"><input name="_dynSessConf" type="hidden" value="8232044757435438897"/> </div><input name="/atg/userprofiling/ProfileFormHandler.countryCode" id="newCountryCode" type="text" value=""/><input name="_D:/atg/userprofiling/ProfileFormHandler.countryCode" type="hidden" value=" "/><input name="/atg/userprofiling/ProfileFormHandler.updateLocation" id="newCountryBtn" type="hidden" value="update"/><input name="_D:/atg/userprofiling/ProfileFormHandler.updateLocation" type="hidden" value=" "/><div style="display:none"><input name="_DARGS" type="hidden" value="/include/popup/Country-Selector-Modal.jsp.updateCountryForm"/> </div></form></div> <div class="contentHtmlBlockModal modal" data-backdrop="true" id="showMoreModal"> <div class="contentHtmlBlockModalContent modal-dialog modal-dialog-centered"> <div class="modal-content"> <div class='modal-body'> <div class="container-fluid"> <button type="button" class="closeModal close" data-dismiss="modal" aria-label="Close"> <span aria-hidden="true">×</span> </button> <div class="col-sm-2" id='leftModal'></div> <div class="col-sm-10" id='middleModal'> <div id="titleModal"> </div> <div id="contentModal"></div> </div> </div> </div> </div> </div> </div> <!-- "Cart Redirect" Modal Popup --> <div id="img-enlargement" class="modal fade" role="dialog"> <div class="modal-dialog" role="document"> <div class="modal-content"> <div class="modal-body"> <img id="img-container"> </div> </div> </div> </div> <div id="hiddenGlobalForms"> <form method="post" action="/;jsessionid=1rqEEXhldyMB8XDE6dLxobETGccQoFeTjDRrxd_N.awsprod_store04?_DARGS=/common/content/content.jsp.globalAddItemToGiftlistForm" style="display:none;" id="globalAddItemToGiftlistForm"><div style="display:none"><input name="_dyncharset" type="hidden" value="UTF-8"/> </div><div style="display:none"><input name="_dynSessConf" type="hidden" value="8232044757435438897"/> </div><input name="/atg/commerce/gifts/GiftlistFormHandler.giftlistId" type="hidden" class="globalAddItemToGiftlistForm_giftlistId" value=""/><input name="_D:/atg/commerce/gifts/GiftlistFormHandler.giftlistId" type="hidden" value=" "/><input name="/atg/commerce/gifts/GiftlistFormHandler.productId" type="hidden" class="globalAddItemToGiftlistForm_productId" value=""/><input name="_D:/atg/commerce/gifts/GiftlistFormHandler.productId" type="hidden" value=" "/><input name="/atg/commerce/gifts/GiftlistFormHandler.catalogRefIds" type="hidden" class="globalAddItemToGiftlistForm_skuIds" value=""/><input name="_D:/atg/commerce/gifts/GiftlistFormHandler.catalogRefIds" type="hidden" value=" "/><input name="/atg/commerce/gifts/GiftlistFormHandler.quantity" type="hidden" class="globalAddItemToGiftlistForm_qty" value=""/><input name="_D:/atg/commerce/gifts/GiftlistFormHandler.quantity" type="hidden" value=" "/><input name="/atg/commerce/gifts/GiftlistFormHandler.addItemToGiftlistSuccessURL" type="hidden" value="/ajax/form/json/globalAddItemToGiftlistResponse.jsp?operation=addItemToGiftlist&amp;result=success"/><input name="_D:/atg/commerce/gifts/GiftlistFormHandler.addItemToGiftlistSuccessURL" type="hidden" value=" "/><input name="/atg/commerce/gifts/GiftlistFormHandler.addItemToGiftlistErrorURL" type="hidden" value="/ajax/form/json/globalAddItemToGiftlistResponse.jsp?operation=addItemToGiftlist&amp;result=error"/><input name="_D:/atg/commerce/gifts/GiftlistFormHandler.addItemToGiftlistErrorURL" type="hidden" value=" "/><input name="/atg/commerce/gifts/GiftlistFormHandler.addItemToGiftlist" type="hidden" value="submit"/><input name="_D:/atg/commerce/gifts/GiftlistFormHandler.addItemToGiftlist" type="hidden" value=" "/><div style="display:none"><input name="_DARGS" type="hidden" value="/common/content/content.jsp.globalAddItemToGiftlistForm"/> </div></form></div> <script type="text/javascript" src="//media.cellsignal.com/www/dist/76.5.0/js/vendor.min.js"></script> <script type="text/javascript" src="//media.cellsignal.com/www/dist/76.5.0/js/vendor-vue.min.js"></script> <script type="text/javascript" src="//media.cellsignal.com/www/dist/76.5.0/js/common.min.js"></script> <script src="/nuxt/serve/ct/index.iife.js"></script> <script src="//media.cellsignal.com/www/dist/76.5.0/js/api-ct.bundle.min.js"></script> <script type="text/javascript" src="//media.cellsignal.com/www/dist/76.5.0/js/generic-content.min.js"></script> <script> var NoCacheForJS = false; var loggingDebug = false; </script> <!-- end body itemscope WebPage --> <script>(function(){function c(){var b=a.contentDocument||a.contentWindow.document;if(b){var d=b.createElement('script');d.innerHTML="window.__CF$cv$params={r:'8e775aca594c9e2f',t:'MTczMjQyOTg3Mi4wMDAwMDA='};var a=document.createElement('script');a.nonce='';a.src='/cdn-cgi/challenge-platform/scripts/jsd/main.js';document.getElementsByTagName('head')[0].appendChild(a);";b.getElementsByTagName('head')[0].appendChild(d)}}if(document.body){var a=document.createElement('iframe');a.height=1;a.width=1;a.style.position='absolute';a.style.top=0;a.style.left=0;a.style.border='none';a.style.visibility='hidden';document.body.appendChild(a);if('loading'!==document.readyState)c();else if(window.addEventListener)document.addEventListener('DOMContentLoaded',c);else{var e=document.onreadystatechange||function(){};document.onreadystatechange=function(b){e(b);'loading'!==document.readyState&&(document.onreadystatechange=e,c())}}}})();</script></body> </html>

Pages: 1 2 3 4 5 6 7 8 9 10