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{"work":{"id":62342779,"created_at":"2021-11-25T03:07:27.430-08:00","from_world_paper_id":184711006,"updated_at":"2024-11-25T21:46:36.395-08:00","_data":{"publisher":"JSTOR","grobid_abstract":"The purpose of this study was to evaluate the relationship of long-term concentrations of ambient air pollutants and risk of incident lung cancer in nonsmoking Caifornia adults. A cohort study of 6,338 nonsmoking, non-Hispanic, white Califorian adults, ages 27-95, was followed from 1977 to 1992 for newly diagnosed cancers. Monthly ambient air pollution data were interpolated to zip code centroids according to home and work location histories, cumulated, and then averaged over time. The increased relative risk (RR) ofincident lung cancer in mdes associated with an interquartile range (IQR) increase in 100 ppb ozone (03) was 3.56 [95% confidence interval (CI), 1.35-9.42]. Incident lung cancer in males was also positively asoated with IQR increases for mean concentrations of particulate matter \u003c10 Pm (PM1O; RR = 5.21; CI, 1.94-13.99) and SO2 (RR = 2.66; CI, 1.624.39). For females, incident lung cancer was positively associated with IQR increases for S02 (RR-2.14; CI, 1.36-3.37) and IQR increas for PM10 exceedace frequencies of 50 pglm3 (RR = 1.21; CI, 0.55-2.66) and 60 pgWm3 (RR m 1.25; CI, 0.57-2.71). Increased risks of incident lung cancer were associated with elevated longterm ambient concentrations of PM10 and SO2 in both genders and with 03 in males. The gender differences for the 03 and PM10 results appeared to be piaMly due to gender differences in expsure. Key work air pollution, lung cancer, nitrogen dioxide, ozone, particulate matter, Seventh-day Adventists, sulfur dioxide, troposphere. Environ Health Perspect 106:813-823 (1998).","publication_date":"1998,,","publication_name":"Environmental Health Perspectives","grobid_abstract_attachment_id":"75141293"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Long-Term Concentrations of Ambient Air Pollutants and Incident Lung Cancer in California Adults: Results from the AHSMOG Study","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [87003530]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div 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data-landing_url="https://www.academia.edu/62342779/Long_Term_Concentrations_of_Ambient_Air_Pollutants_and_Incident_Lung_Cancer_in_California_Adults_Results_from_the_AHSMOG_Study" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="62342926" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/62342926/The_Association_between_Ambient_Fine_Particulate_Air_Pollution_and_Lung_Cancer_Incidence_Results_from_the_AHSMOG_2_Study">The Association between Ambient Fine Particulate Air Pollution and Lung Cancer Incidence: Results from the 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class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="233511" href="https://dal.academia.edu/DanielRainham">Daniel Rainham</a></div><p class="ds-related-work--metadata ds2-5-body-xs">… of Toxicology and …, 2005</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Mortality and Long-Term Exposure to Ambient Air Pollution: Ongoing Analyses Based on the American Cancer Society Cohort","attachmentId":3243818,"attachmentType":"pdf","work_url":"https://www.academia.edu/297820/Mortality_and_Long_Term_Exposure_to_Ambient_Air_Pollution_Ongoing_Analyses_Based_on_the_American_Cancer_Society_Cohort","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a 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Katsoulis</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Background: Particulatematter (PM) air pollution is a human lung carcinogen; however, the components responsible have not been identified.We assessed the associations between PMcomponents and lung cancer incidence. Methods: Weused data from 14 cohort studies in eight European countries. Wegeocoded baseline addresses and assessed air pollution with land-use regression models for eight elements (Cu, Fe, K, Ni, S, Si, V and Zn) in size fractions of PM2.5 and PM10. We used Cox regression models with adjustment for potential confounders for cohort-specific analyses and random effect models for meta-analysis. Results: The 245,782 cohort members contributed 3,229,220 person–years at risk. During follow-up (mean, 13.1 years), 1878 incident cases of lung cancer were diagnosed. In the meta-analyses, elevated hazard ratios (HRs) for lung cancer were associated with all elements except V; none was statistically significant. In analyses restricted to participants who did not change residence during follow-up, statistically significant associations were found for PM2.5 Cu (HR, 1.25; 95% CI, 1.01–1.53 per 5 ng/m3), PM10 Zn (1.28; 1.02–1.59 per 20 ng/m3), PM10 S (1.58; 1.03–2.44 per 200 ng/m3), PM10 Ni (1.59; 1.12–2.26 per 2 ng/m3) and PM10 K (1.17; 1.02–1.33 per 100 ng/m3). In two-pollutant models, associations between PM10 and PM2.5 and lung cancer were largely explained by PM2.5 S. Conclusions: This study indicates that the association between PMin air pollution and lung cancer can be attributed to various PM components and sources. 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