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<!doctype html> <html lang="fr"> <head> <title>Understanding Testosterone Deficiency in Depression: Insight | 1099779</title> <meta name="keywords" content="Jiaojiao Huang, Zhen Peng, Zhenhua Song*, "/> <meta name="description" content="This study mainly focused on the role of cholesterol dynamics in leydig cells to understanding testosterone deficiency in depression. Numerous studies have..1099779"/> <meta name="citation_publisher" content="Longdom Publishing SL" /> <meta name="citation_journal_title" content="Andrologie-Open Access"> <meta name="citation_title" content="Understanding Testosterone Deficiency in Depression: Insights from Cholesterol Dynamics in Leydig Cells of CUMS Mice"> <meta name="citation_author" content="Jiaojiao Huang" /> <meta name="citation_author" content="Zhen Peng" /> <meta name="citation_author" content="Zhenhua Song" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="13"> <meta name="citation_issue" content="5"> <meta name="citation_abstract" content="This study mainly focused on the role of cholesterol dynamics in leydig cells to understanding testosterone deficiency in depression. Numerous studies have demonstrated a link between a higher risk of depression and low testosterone levels. Males with low testosterone frequently experience depressive symptoms and testosterone replacement therapy has been demonstrated to elevate mood in certain testosterone deficient individuals. Meanwhile, depression is frequently associated with hormonal imbalances, including testosterone deficiency. Recent research using chronic unexpected mild stress (CUMS) mice models has uncovered a significant connection between reduced testosterone levels and diminished cholesterol levels in Leydig cells, which are vital for testosterone production. This relationship highlights a significant intersection between mood disorders and metabolic processes."> <meta name="citation_abstract_html_url" content="https://french.longdom.org/abstract/understanding-testosterone-deficiency-in-depression-insights-from-cholesterol-dynamics-in-leydig-cells-of-cums-mice-1099779.html"> <meta name="format-detection" content="telephone=no"> <meta http-equiv="Content-Language" content="fr"> <meta name="google-site-verification" content="NomPTP94YozsgvD3NEFpNqUfY88e0TU0L64zNzZTpd0" /> <meta itemprop="name" content="longdom" /> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta name="ROBOTS" content="INDEX,FOLLOW"> <meta name="googlebot" content="INDEX,FOLLOW"> <meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"> <link rel="canonical" href="https://french.longdom.org/abstract/understanding-testosterone-deficiency-in-depression-insights-from-cholesterol-dynamics-in-leydig-cells-of-cums-mice-1099779.html"> <link 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Numerous studies have demonstrated a link between a higher risk of depression and low testosterone levels. Males with low testosterone frequently experience depressive symptoms and testosterone replacement therapy has been demonstrated to elevate mood in certain testosterone deficient individuals. Meanwhile, depression is frequently associated with hormonal imbalances, including testosterone deficiency. Recent research using chronic unexpected mild stress (CUMS) mice models has uncovered a significant connection between reduced testosterone levels and diminished cholesterol levels in Leydig cells, which are vital for testosterone production. This relationship highlights a significant intersection between mood disorders and metabolic processes.</p> <div class="alert alert-info text-left"><b>Clause de non-responsabilit茅:</b> Ce r茅sum茅 a 茅t茅 traduit 脿 l'aide d'outils d'intelligence artificielle et n'a pas encore 茅t茅 r茅vis茅 ou v茅rifi茅.</div> <div class="nav social-icons"> <a class="nav-link w-auto">Partagez cet article</a> <a title="Cliquez ici" target="_blank" href="https://www.facebook.com/sharer.php?u=https://french.longdom.org/abstract/understanding-testosterone-deficiency-in-depression-insights-from-cholesterol-dynamics-in-leydig-cells-of-cums-mice-1099779.html" rel="noopener"><i class="fab fa-facebook-f"></i></a> <a class="nav-link" title="Cliquez ici" target="_blank" href="https://twitter.com/share?url=https://french.longdom.org/abstract/understanding-testosterone-deficiency-in-depression-insights-from-cholesterol-dynamics-in-leydig-cells-of-cums-mice-1099779.html" rel="noopener"><i class="fab fa-twitter"></i></a> <a class="nav-link" title="Cliquez ici" target="_blank" href="https://www.linkedin.com/shareArticle?mini=true&url=https://french.longdom.org/abstract/understanding-testosterone-deficiency-in-depression-insights-from-cholesterol-dynamics-in-leydig-cells-of-cums-mice-1099779.html" rel="noopener"><i class="fab fa-linkedin-in"></i></a> <a class="nav-link" title="Cliquez ici" target="_blank" href="https://plus.google.com/share?url=https://french.longdom.org/abstract/understanding-testosterone-deficiency-in-depression-insights-from-cholesterol-dynamics-in-leydig-cells-of-cums-mice-1099779.html" rel="noopener"><i class="fab fa-google-plus-g"></i></a> </div> </div> </div> </div> </section> <footer class="bg-blue-grey-900 py-3"> <div class="container"> <div class="row"> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Liens de contenu</h4> <ul class="list-unstyled footer-links font-size-3"> <li><a class="" href="https://french.longdom.org/privacy-policy.html" title="Cliquez ici">politique de confidentialit茅</a></li> <li><a class="" href="https://french.longdom.org/terms-conditions.html" title="Cliquez ici">termes et conditions</a></li> <li><a class="" href="https://french.longdom.org/authors-reviewers-editors.html" title="Cliquez ici">Auteurs, critiques et 茅diteur</a></li> </ul> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Contacter Longdom</h4> <p><strong>Groupe Longdom SA</strong><br /> Avenue Roger Vandendriessche,<br /> 18, 1150 Bruxelles, Belgique<br /> T茅l茅phone : +442038085340<br /> <strong>Courriel :</strong> <a class="white" href="mailto:info@longdom.org" title="Cliquez ici">info@longdom.org</a></p> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Connecter</h4> <nav class="nav nav-pills social-icons-footer flex-column a-pl-0"> <a href="https://www.facebook.com/longdompublisher" title="Cliquez ici" target="_blank" class="nav-link bg-facebook-hover"><i class="fab fa-facebook-f bg-facebook"></i></a> <a href="https://www.linkedin.com/company/longdom-publishing-sl/" title="Cliquez ici" target="_blank" class="nav-link bg-linkedin-hover"><i class="fab fa-linkedin-in bg-linkedin"></i></a> <a href="https://twitter.com/LongdomP" title="Cliquez ici" target="_blank" class="nav-link bg-twitter-hover"><i class="fab fa-twitter bg-twitter"></i></a> <a href="https://www.instagram.com/longdom_publisher/" title="Cliquez ici" target="_blank" class="nav-link bg-instagram-hover"><i class="fab fa-instagram bg-instagram"></i></a> </nav> </div> </div> <div class="row text-center"> <div class="col"> <p>droits d auteur © 2024 <a href="https://french.longdom.org/" title="Cliquez ici" class="white">Longdom 脡ditions SL</a>.</p> </div> </div> </div> </footer>  <a href="#0" class="cd-top js-cd-top">Top</a>   <script src="https://code.jquery.com/jquery-3.3.1.min.js"></script> <script src="https://cdnjs.cloudflare.com/ajax/libs/popper.js/1.14.7/umd/popper.min.js"></script> <script src="https://stackpath.bootstrapcdn.com/bootstrap/4.3.1/js/bootstrap.min.js"></script>  <script> jQuery(function($) { $(window).scroll(function fix_element() { $('#target').css( $(window).scrollTop() > 100 ? 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