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(PDF) Toxic inner ear lesion following otitis media with effusion: a comparative CT-study regarding the morphology of the inner ear | Thomas W Wilhelm and Christian Güldner - Academia.edu

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The treatment of choice" /> <title>(PDF) Toxic inner ear lesion following otitis media with effusion: a comparative CT-study regarding the morphology of the inner ear | Thomas W Wilhelm and Christian Güldner - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/27622458/Toxic_inner_ear_lesion_following_otitis_media_with_effusion_a_comparative_CT_study_regarding_the_morphology_of_the_inner_ear" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '668dc9b1eac5251aedbeadf5495ba8efeff5c4ef'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732555423000); window.Aedu.timeDifference = new Date().getTime() - 1732555423000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Viral infections of the upper respiratory airways can lead to a delayed viral otitis media (VOM) caused by a diffusion of viruses/virus particles through the round window membrane and resulting in sensorineural hearing loss. The treatment of choice is immediate paracentesis, evacuation of all fluids from the middle ear cavity, and haemorrheological infusions. However, in some cases, persistent symptoms may be an indication for a surgical approach using mastoidectomy. In high-resolution computed tomography, an extended small-sized pneumatisation of the mastoid cells with complete shading was found in these non-responsive cases. Therefore, a direct means of inner ear affliction through weak parts of the labyrinthine bone may be hypothesised. Patients suffering from a toxic inner ear lesion (TIEL) following a common cold, treated over a 10-year period in a Tertiary Care Centre (N = 52, 57 ears), were identified and the morphological characteristics of the temporal bones of affected pat...","author":[{"@context":"https://schema.org","@type":"Person","name":"Thomas W Wilhelm"},{"@context":"https://schema.org","@type":"Person","name":"Christian Güldner"}],"contributor":[{"@context":"https://schema.org","@type":"Person","name":"Christian Güldner"}],"dateCreated":"2016-08-08","dateModified":"2016-08-31","datePublished":"2014-01-07","headline":"Toxic inner ear lesion following otitis media with effusion: a comparative CT-study regarding the morphology of the inner ear","inLanguage":"en","keywords":["Treatment Outcome","Humans","Female","Male","Inner Ear","Clinical Sciences","Aged","Middle Aged","Adult","Retrospective Studies","Temporal Bone","X ray Computed Tomography","Otitis Media with Effusion","Paracentesis","Mastoiditis"],"locationCreated":null,"publication":"European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery","publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/27622458/Toxic_inner_ear_lesion_following_otitis_media_with_effusion_a_comparative_CT_study_regarding_the_morphology_of_the_inner_ear","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":"uni-marburg"},{"@context":"https://schema.org","@type":"EducationalOrganization","name":"setmarburg"}]}</script><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/single_work_page/loswp-352e32ba4e89304dc0b4fa5b3952eef2198174c54cdb79066bc62e91c68a1a91.css" /><link rel="stylesheet" media="all" 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{"work":{"id":27622458,"created_at":"2016-08-08T06:47:54.732-07:00","from_world_paper_id":156367171,"updated_at":"2021-01-13T15:04:50.430-08:00","_data":{"abstract":"Viral infections of the upper respiratory airways can lead to a delayed viral otitis media (VOM) caused by a diffusion of viruses/virus particles through the round window membrane and resulting in sensorineural hearing loss. The treatment of choice is immediate paracentesis, evacuation of all fluids from the middle ear cavity, and haemorrheological infusions. However, in some cases, persistent symptoms may be an indication for a surgical approach using mastoidectomy. In high-resolution computed tomography, an extended small-sized pneumatisation of the mastoid cells with complete shading was found in these non-responsive cases. Therefore, a direct means of inner ear affliction through weak parts of the labyrinthine bone may be hypothesised. Patients suffering from a toxic inner ear lesion (TIEL) following a common cold, treated over a 10-year period in a Tertiary Care Centre (N = 52, 57 ears), were identified and the morphological characteristics of the temporal bones of affected pat...","publication_date":"2014,1,7","publication_name":"European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Toxic inner ear lesion following otitis media with effusion: a comparative CT-study regarding the morphology of the inner ear","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [51821462,33234323]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;swp-splash-paper-cover&quot;,&quot;attachmentId&quot;:47886916,&quot;attachmentType&quot;:&quot;pdf&quot;}"><img alt="First page of “Toxic inner ear lesion following otitis media with effusion: a comparative CT-study regarding the morphology of the inner ear”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/47886916/mini_magick20190205-2019-kpd9d3.png?1549400130" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Toxic inner ear lesion following otitis media with effusion: a comparative CT-study regarding the morphology of the inner ear</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="51821462" href="https://uni-marburg.academia.edu/ThomasWilhelm"><img alt="Profile image of Thomas W Wilhelm" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/51821462/13934556/14991662/s65_thomas.wilhelm.jpg" />Thomas W Wilhelm</a><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="33234323" href="https://setmarburg.academia.edu/ChristianG%C3%BCldner"><img alt="Profile image of Christian Güldner" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Christian Güldner</a></div><p class="ds-work-card--detail ds2-5-body-sm">2014, European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery</p><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Viral infections of the upper respiratory airways can lead to a delayed viral otitis media (VOM) caused by a diffusion of viruses/virus particles through the round window membrane and resulting in sensorineural hearing loss. The treatment of choice is immediate paracentesis, evacuation of all fluids from the middle ear cavity, and haemorrheological infusions. However, in some cases, persistent symptoms may be an indication for a surgical approach using mastoidectomy. In high-resolution computed tomography, an extended small-sized pneumatisation of the mastoid cells with complete shading was found in these non-responsive cases. Therefore, a direct means of inner ear affliction through weak parts of the labyrinthine bone may be hypothesised. Patients suffering from a toxic inner ear lesion (TIEL) following a common cold, treated over a 10-year period in a Tertiary Care Centre (N = 52, 57 ears), were identified and the morphological characteristics of the temporal bones of affected pat...</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--work-card&quot;,&quot;attachmentId&quot;:47886916,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:&quot;https://www.academia.edu/27622458/Toxic_inner_ear_lesion_following_otitis_media_with_effusion_a_comparative_CT_study_regarding_the_morphology_of_the_inner_ear&quot;}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--work-card&quot;,&quot;attachmentId&quot;:47886916,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:&quot;https://www.academia.edu/27622458/Toxic_inner_ear_lesion_following_otitis_media_with_effusion_a_comparative_CT_study_regarding_the_morphology_of_the_inner_ear&quot;}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="47886916" data-landing_url="https://www.academia.edu/27622458/Toxic_inner_ear_lesion_following_otitis_media_with_effusion_a_comparative_CT_study_regarding_the_morphology_of_the_inner_ear" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="41143615" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/41143615/The_computed_tomographical_and_tympanometrical_evaluation_of_mastoid_pneumatization_and_attic_blockage_in_patients_with_chronic_otitis_media_with_effusion">The computed tomographical and tympanometrical evaluation of mastoid pneumatization and attic blockage in patients with chronic otitis media with effusion</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33569169" href="https://independent.academia.edu/CengizOzcan">Cengiz Ozcan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International journal of pediatric otorhinolaryngology, 2006</p><p class="ds-related-work--abstract ds2-5-body-sm">To assess the relation between mastoid size and attic blockage in COME patients treated with ventilation tube insertion and prognosis regarding tympanometric compliance and computed tomography findings of temporal bones. Twenty-four ears of 15 patients with chronic otitis media with effusion were selected prospectively. The ages of patients were between 5 and 13 years old and eight of them were females. All patient received medical treatment for 10 days. Ventilation tubes were inserted with or without adenoidectomy or adenotonsillectomy to the unimproved patients. Postoperative compliances were measured on first day, first week, and first month and the tympanometric results were compared each one with others and with mastoid pneumatization degree using computerized tomographic findings. The hearing thresholds were between 23 and 43 dB in left ears and between 22 and 45 dB in right ears. 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Histopathological changes: a post mortem study on temporal bones</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="51985959" href="https://independent.academia.edu/MaurizioTrivelli">Maurizio Trivelli</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European review for medical and pharmacological sciences</p><p class="ds-related-work--abstract ds2-5-body-sm">A classification of otitis media is proposed and the histopathological changes of otitis media with effusion are reviewed post mortem on two temporal bones. A case of adhesive otitis media is observed on temporal bone slides. The clinical and therapeutic aspect are examined and treatment guidelines are proposed.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Acute otitis media. Histopathological changes: a post mortem study on temporal bones&quot;,&quot;attachmentId&quot;:114118777,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/118510093/Acute_otitis_media_Histopathological_changes_a_post_mortem_study_on_temporal_bones&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/118510093/Acute_otitis_media_Histopathological_changes_a_post_mortem_study_on_temporal_bones"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="88889232" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/88889232/Unusual_complications_of_otitis_media">Unusual complications of otitis media</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="160916444" href="https://independent.academia.edu/LilianaLupu4">Liliana Lupu</a></div><p class="ds-related-work--metadata ds2-5-body-xs">American Journal of Otolaryngology, 1994</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Unusual complications of otitis media&quot;,&quot;attachmentId&quot;:92788256,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/88889232/Unusual_complications_of_otitis_media&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/88889232/Unusual_complications_of_otitis_media"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="17185744" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/17185744/Importance_of_mastoid_pneumatization_on_secretory_otitis_media">Importance of mastoid pneumatization on secretory otitis media</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="810394" href="https://pamukkale.academia.edu/b%C3%BClenttopuz">bülent topuz</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="7124293" href="https://pamukkale.academia.edu/C%C3%BCneytOrhanKara">Cüneyt Orhan Kara</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Pediatric Otorhinolaryngology, 1997</p><p class="ds-related-work--abstract ds2-5-body-sm">Secretory otitis media is the most common middle ear disease of childhood. It heals spontaneously, by medical therapy or by minor surgical procedures in most of the cases. Sequelae such as retraction pockets and adhesive otitis that lead to cholesteatoma rarely occur, but initially it is hard to diagnose which patient will acquire a sequela. It is well known that mastoid pneumatization is poor in the patients who had complications like retraction pocket, adhesive otitis and cholesterol granuloma. The aim of this study was to determine if any relationship exists between mastoid pneumatization and secretory otitis media. Lateral mastoid X-rays of 47 children with secretory otitis media were evaluated. After 2 months of follow-up with medical therapy, 30 of the 47 patients needed ventilation tube insertion. The remaining 17 patients showed total recovery with medicines only. Control X-rays of the operated patients were taken 6 months after the operation. Mastoid pneumatizations of patients healed with medicine were compared with the operated patients. There were statistically significant differences between the mastoid pneumatizations of surgically and medically treated groups. In addition we observed a statistically significant difference between the mastoid areas of the preoperative and the postoperative X-rays. We concluded that mastoid pneumatization might be considered as a prognostic indicator in secretory otitis media. The estimated prognosis is poor when the mastoid pneumatization is poor.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Importance of mastoid pneumatization on secretory otitis media&quot;,&quot;attachmentId&quot;:42295537,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/17185744/Importance_of_mastoid_pneumatization_on_secretory_otitis_media&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/17185744/Importance_of_mastoid_pneumatization_on_secretory_otitis_media"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="95931112" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/95931112/The_Role_of_CT_Scan_inThe_Evaluation_of_Serous_Otitis_Media">The Role of CT-Scan inThe Evaluation of Serous Otitis Media</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="248510187" href="https://independent.academia.edu/omarramadan67">omar ramadan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Global Journal of Otolaryngology, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;The Role of CT-Scan inThe Evaluation of Serous Otitis Media&quot;,&quot;attachmentId&quot;:97972266,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/95931112/The_Role_of_CT_Scan_inThe_Evaluation_of_Serous_Otitis_Media&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/95931112/The_Role_of_CT_Scan_inThe_Evaluation_of_Serous_Otitis_Media"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="14282118" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/14282118/Intracranial_complications_of_otitis_media_15_years_of_experience_in_33_patients">Intracranial complications of otitis media: 15 years of experience in 33 patients</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33414424" href="https://unifesp.academia.edu/LuizIha">Luiz Iha</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33246732" href="https://unifesp.academia.edu/Vin%C3%ADciusSuguri">Vinícius Suguri</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33406249" href="https://unifesp.academia.edu/NormaDeOliveiraPenido">Norma De Oliveira Penido</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33642201" href="https://unifesp.academia.edu/EktorOnishi">Ektor Onishi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Otolaryngology - Head and Neck Surgery, 2005</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Intracranial complications of otitis media: 15 years of experience in 33 patients&quot;,&quot;attachmentId&quot;:44358854,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/14282118/Intracranial_complications_of_otitis_media_15_years_of_experience_in_33_patients&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/14282118/Intracranial_complications_of_otitis_media_15_years_of_experience_in_33_patients"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="36816689" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/36816689/Role_of_high_resolution_computed_tomography_of_temporal_bone_in_management_of_chronic_suppurative_otitis_media">Role of high resolution computed tomography of temporal bone in management of chronic suppurative otitis media</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="77569005" href="https://digitaluniversity.academia.edu/AjeetKumarKhilnani">Ajeet Kumar Khilnani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Otorhinolaryngology and Head and Neck Surgery</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Role of high resolution computed tomography of temporal bone in management of chronic suppurative otitis media&quot;,&quot;attachmentId&quot;:56767637,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/36816689/Role_of_high_resolution_computed_tomography_of_temporal_bone_in_management_of_chronic_suppurative_otitis_media&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/36816689/Role_of_high_resolution_computed_tomography_of_temporal_bone_in_management_of_chronic_suppurative_otitis_media"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="70548441" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/70548441/Interrelations_between_the_middle_and_inner_ear_in_otitis_media">Interrelations between the middle and inner ear in otitis media</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="52424279" href="https://independent.academia.edu/PedroEscada">Pedro Escada</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The international tinnitus journal, 2003</p><p class="ds-related-work--abstract ds2-5-body-sm">This article reviews the importance of the round-window membrane in exposing the labyrinth to or protecting it from the toxic effects of otitis media. Characteristics of the immune system in the human middle ear and middle-ear mechanisms against bacteria are explained. The role of bacteria and bacterial products in inner-ear damage is detailed, and related pathological events are described. The hypothetical role of inflammatory mediators in bacteria-induced inner-ear toxicity is particularly emphasized. Clinical conditions causing these events are detailed, and the most frequently involved microorganisms are mentioned. Finally, round-window membrane macroscopic and microscopic anatomy is discussed, and considerations about the exact role of membrane inflammation--protection versus damage of the inner ear--are expressed.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Interrelations between the middle and inner ear in otitis media&quot;,&quot;attachmentId&quot;:80255209,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/70548441/Interrelations_between_the_middle_and_inner_ear_in_otitis_media&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/70548441/Interrelations_between_the_middle_and_inner_ear_in_otitis_media"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--sticky-ctas&quot;,&quot;attachmentId&quot;:47886916,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--sticky-ctas&quot;,&quot;attachmentId&quot;:47886916,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_47886916" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="102383245" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/102383245/Pneumatization_Pattern_and_Status_of_the_Mastoid_Antrum_in_Chronic_Otitis_Media_A_Review">Pneumatization Pattern and Status of the Mastoid Antrum in Chronic Otitis Media: A Review</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="271295321" href="https://independent.academia.edu/SagarGaurkar">Sagar Gaurkar</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Cureus</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Pneumatization Pattern and Status of the Mastoid Antrum in Chronic Otitis Media: A Review&quot;,&quot;attachmentId&quot;:102668624,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/102383245/Pneumatization_Pattern_and_Status_of_the_Mastoid_Antrum_in_Chronic_Otitis_Media_A_Review&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/102383245/Pneumatization_Pattern_and_Status_of_the_Mastoid_Antrum_in_Chronic_Otitis_Media_A_Review"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="1" data-entity-id="118672891" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/118672891/Comparative_evaluation_of_mastoid_pneumatization_pattern_using_X_ray_mastoid_and_high_resolution_computed_tomography_temporal_bone_in_unilateral_squamosal_chronic_otitis_media">Comparative evaluation of mastoid pneumatization pattern using X-ray mastoid and high-resolution computed tomography temporal bone in unilateral squamosal chronic otitis media</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="302867845" 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href="https://www.academia.edu/17610277/Otoscopic_diagnosis_of_middle_ear_effusion_in_acute_and_non_acute_otitis_media_I_The_value_of_different_otoscopic_findings">Otoscopic diagnosis of middle ear effusion in acute and non-acute otitis media. I. The value of different otoscopic findings</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37455690" href="https://independent.academia.edu/MattiKataja">Matti Kataja</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International journal of pediatric otorhinolaryngology, 1989</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Otoscopic diagnosis of middle ear effusion in acute and non-acute otitis media. I. 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