CINXE.COM

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class="sf-depth-2 sf-no-children"><a href="/about-alnylam/corporate-responsibility" class="sf-depth-2">Corporate Responsibility</a></li><li id="mobile-main-menu-menu-link-content2349be8e-3924-4327-95cd-599c456be6f5" class="sf-depth-2 sf-no-children"><a href="/about-alnylam/diversity-inclusion" class="sf-depth-2">Diversity, Equity & Inclusion</a></li><li id="mobile-main-menu-menu-link-content369c2613-4f95-495f-b97d-7fe7704c1281" class="sf-depth-2 sf-no-children"><a href="https://investors.alnylam.com/press-releases" class="sf-depth-2 sf-external">Press Releases</a></li><li id="mobile-main-menu-menu-link-content9624843b-3ef8-4260-97fc-4719352453f5" class="sf-depth-2 sf-no-children"><a href="https://capella.alnylam.com/our-science/capella-rnai-innovation/" class="sf-depth-2 sf-external">Capella (Scientific Presentations)</a></li><li id="mobile-main-menu-menu-link-content8852cdce-87dc-4c88-be02-219bdc7a435f" class="sf-depth-2 sf-no-children"><a href="https://www.rnaiscience.com/" 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</span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.jp/">日本語</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--110 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Belgium</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-belgium-dutch"> Nederlands</a></div> <div class="field--item"><a href="/alnylam-belgium-french">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--109 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Luxembourg</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-luxembourg-french">Français</a></div> <div class="field--item"><a href="/alnylam-luxembourg-german"> Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--112 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Brazil </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.com.br/">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--111 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Netherlands </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-netherlands">Nederlands</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--114 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Canada </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.ca/fr">Français </a></div> <div class="field--item"><a href="https://www.alnylam.ca/">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--113 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Portugal</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-portugal">Português</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1513 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Czech Republic</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-czech-republic">Čeština</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--115 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Spain </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-espana">Español</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--116 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Denmark </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-denmark">Dansk</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--117 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Sweden</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-sverige">Svenska</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--118 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">France</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.fr/">Français</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--119 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Switzerland</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-switzerland-french">Français</a></div> <div class="field--item"><a href="/alnylam-switzerland-german">Deutsch</a></div> <div class="field--item"><a href="/alnylam-switzerland-italian">Italiano</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--120 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Germany </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.de/">Deutsch</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--121 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Taiwan</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-taiwan">繁體中文</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--1514 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Ireland </div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-ireland">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--123 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">United Kingdom</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="/alnylam-uk">English</a></div> </div> </span> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--language-links paragraph-id--122 paragraph--view-mode--default"> <div class="language-switcher-main"> <span class="label-text"> <div class="field field--name-field-label field--type-string field--label-hidden field--item">Italy</div> </span><span class="link-text"> <div class="field field--name-field-link1 field--type-link field--label-hidden field--items"> <div class="field--item"><a href="https://www.alnylam.it/">Italiano</a></div> </div> </span> </div> </div> </div> </div> </section> </div> </div> </div> </div> </header> <div id="maindiv" class="container-fluid"> <main id="midcontent-area" class="column main-content"> <div id="content"> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <article data-history-node-id="1620" role="article" about="/medical-publication-support" typeof="schema:WebPage" class="page full clearfix"> <span property="schema:name" content="Medical Publication Support" class="hidden"></span> <div class="content"> <div class="field field--name-field-add-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--sim paragraph-id--1587 paragraph--view-mode--default"> <div id="simple-banner-wrapper"> <div class="simple-banner" style=""> <div class="field field--name-field-upload-image field--type-image field--label-hidden field--item"> <img src="/sites/default/files/2022-04/publucation-support-banner.jpg" width="2560" height="770" alt="Medical Publication Support" loading="lazy" typeof="foaf:Image" class="img-responsive" /> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--banner-overlay-html-content paragraph-id--1588 paragraph--view-mode--default"> <div class="banner-overlay-html-content-description--component " style="width:1130px; margin:auto;"> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item"><p class="mobile-eyebrow"><span class="our-secondary-dark">Medical Professionals</span></p> <h1 class="secondary-dark text-align-center"><strong>ALNYLAM MEDICAL – PUBLICATION SUPPORT </strong></h1> <p class="margin-bottom-24px">Communicating the findings from scientific studies, clinical studies, and/or outcomes of clinical practice through publication-related activities is an essential step toward educating the healthcare community.</p> <p class="margin-bottom-24px">As such, Alnylam may consider providing publication support in response to an unsolicited request from a healthcare professional. In accordance with local laws and regulations, support may be provided via direct funding or in the form of services to authors through a third-party provider.</p> <p class="margin-bottom-24px">Alnylam is using SteepRock as its platform for submission and review of unsolicited requests to support external publications. This portal will enable the applicant to submit a proposal for publication work to Alnylam for which support is requested, as well as track the progress of any existing request(s), and close out relevant supported requests.</p> <h3 class="margin-bottom-24px">Established Areas of Support</h3> <p class="margin-bottom-24px">Transthyretin-mediated (TTR) amyloidosis, acute hepatic porphyria (AHP), primary hyperoxaluria (PH), or other therapeutic areas related to our pipeline.</p> <h3 class="margin-bottom-24px">Applicant Requirements/Responsibilities:</h3> <p class="margin-bottom-24px">On this portal, the applicant will be asked to provide information related to the anticipated publication as well as provide supporting documents to help Alnylam’s assessment of the request for support.</p> <p class="margin-bottom-24px">If you have any specific questions regarding our process, please contact your local Medical Affairs representative at Alnylam.</p> <p><strong>The Following Information will be Required:</strong></p> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--body paragraph-id--1589 paragraph--view-mode--default"> <div class="description--component" style="width:970px; margin:auto; "> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item"><svg class="hide_mobile" width="970" height="1098" viewBox="0 0 970 1098" xmlns="http://www.w3.org/2000/svg"> <g fill="none" fill-rule="evenodd"> <path fill="#00254B" d="M0 0h970v64H0z"/> <path fill="#FFF" d="M0 64h970v64H0zM0 192h970v64H0zM0 664h970v88H0zM0 880h970v128H0z"/> <path fill-opacity=".16" fill="#B9D9EB" d="M0 1008h970v88H0zM0 752h970v128H0z"/> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 664)"> <tspan x="32" y="37">Data Source for this </tspan> <tspan x="32" y="61">Proposed Publication</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 664)"> <tspan x="32" y="253">Publication Plan, </tspan> <tspan x="32" y="277">Timelines</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 664)"> <tspan x="32" y="381">Additional Relevant Details</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 664)"> <tspan x="32" y="125">Patients, Methods, </tspan> <tspan x="32" y="149">Timelines</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20" transform="translate(0 664)"> <tspan x="334" y="40" fill="#F90">• </tspan> <tspan x="349.442" y="40.36" font-size="17" fill="#333">Case Study, (electronic) Medical Records, Clinical Trial, Early Access </tspan> <tspan x="349" y="64.36" font-size="17" fill="#333"> Program, Registry, etc</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20" transform="translate(0 664)"> <tspan x="334" y="256" fill="#F90">• </tspan> <tspan x="349.442" y="256.36" font-size="17" fill="#333">Which congress or journal is being targeted? </tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20" transform="translate(0 664)"> <tspan x="334" y="288" fill="#F90">• </tspan> <tspan x="349.442" y="288.36" font-size="17" fill="#333">Is the congress or journal in English? </tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20" transform="translate(0 664)"> <tspan x="334" y="320" fill="#F90">• </tspan> <tspan x="349.442" y="320.36" font-size="17" fill="#333">What is the submission deadline? </tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20" transform="translate(0 664)"> <tspan x="334" y="384" fill="#F90">• </tspan> <tspan x="349.442" y="384.36" font-size="17" fill="#333">Any relevant or supporting documents (quotes, etc) will need to be </tspan> <tspan x="349" y="408.36" font-size="17" fill="#333"> uploaded to complete your request</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20" transform="translate(0 664)"> <tspan x="334" y="128" fill="#F90">• </tspan> <tspan x="349.442" y="128.36" font-size="17" fill="#333">What are the inclusion criteria? </tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20" transform="translate(0 664)"> <tspan x="334" y="160" fill="#F90">• </tspan> <tspan x="349.442" y="160.36" font-size="17" fill="#333">Are any patient types excluded? Proposed analytical approaches?</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20" transform="translate(0 664)"> <tspan x="334" y="192" fill="#F90">• </tspan> <tspan x="349.442" y="192.36" font-size="17" fill="#333">What is the estimated timeline for data analysis?</tspan> </text> <path fill="#FFF" d="M0 424h970v120H0z"/> <path fill-opacity=".16" fill="#B9D9EB" d="M0 544h970v120H0zM0 256h970v168H0zM0 128h970v64H0z"/> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="17" font-weight="bold" fill="#FFF"> <tspan x="32" y="37">Type</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333"> <tspan x="32" y="101">Requester Information</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333"> <tspan x="32" y="229">Proposed Short Title</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333"> <tspan x="32" y="461">Background/Rationale</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333"> <tspan x="32" y="293">Proposed Authors/</tspan> <tspan x="32" y="317">Collaborators</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333"> <tspan x="32" y="165">Therapeutic Area</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333"> <tspan x="32" y="581">Key Research Question, </tspan> <tspan x="32" y="605">Hypothesis</tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="17" font-weight="bold" fill="#FFF"> <tspan x="334" y="37">Specifications</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20"> <tspan x="334" y="104" fill="#F90">• </tspan> <tspan x="349.442" y="104.36" font-size="17" fill="#333">Identification of the requester</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20"> <tspan x="334" y="232" fill="#F90">• </tspan> <tspan x="349.442" y="232.36" font-size="17" fill="#333">Proposed or anticipated title if known</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20"> <tspan x="334" y="464" fill="#F90">• </tspan> <tspan x="349.442" y="464.36" font-size="17" fill="#333">What educational gap would the publication address in the existing literature?</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20"> <tspan x="334" y="496" fill="#F90">• </tspan> <tspan x="349.442" y="496.36" font-size="17" fill="#333">How might it impact clinical decision–making, patient management, or </tspan> <tspan x="349" y="520.36" font-size="17" fill="#333"> the ability to inform future research?</tspan> </text> <g font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20"> <text transform="translate(334 276)"> <tspan x="0" y="20" fill="#F90">• </tspan> <tspan x="15.442" y="20.36" font-size="17" fill="#333">A list of potential authors/collaborators </tspan> </text> <text transform="translate(334 276)"> <tspan x="0" y="52" fill="#F90">• </tspan> <tspan x="15.442" y="52.36" font-size="17" fill="#333">Note that, to ensure compliance with local laws and regulations (eg, US </tspan> <tspan x="15" y="76.36" font-size="17" fill="#333"> Open Payments Act, EFPIA), Alnylam must track and, if applicable, report </tspan> <tspan x="15" y="100.36" font-size="17" fill="#333"> payments or transfers of value associated with certain activities, including </tspan> <tspan x="15" y="124.36" font-size="17" fill="#333"> publication support </tspan> </text> </g> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20"> <tspan x="334" y="168" fill="#F90">• </tspan> <tspan x="349.442" y="168.36" font-size="17" fill="#333">A therapeutic area relevant to Alnylam area(s) of interest</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20"> <tspan x="334" y="584" fill="#F90">• </tspan> <tspan x="349.442" y="584.36" font-size="17" fill="#333">What is the hypothesis? </tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="20"> <tspan x="334" y="616" fill="#F90">• </tspan> <tspan x="349.442" y="616.36" font-size="17" fill="#333">What are the projected key endpoints/measures if applicable?</tspan> </text> <path stroke="#FFF" stroke-width="1.5" stroke-linecap="square" d="M285.5 1.5v1095"/> </g> </svg> <svg class="hide_desktop" width="375" height="2035" viewBox="0 0 375 2035" xmlns="http://www.w3.org/2000/svg"> <g fill="none" fill-rule="evenodd"> <path fill="#FFF" d="M0 65h375v88H0zM0 265h375v112H0zM0 761h375v288H0zM0 1241h375v160H0zM0 1649h375v224H0z"/> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 1)"> <tspan x="32" y="101">Requester </tspan> <tspan x="32" y="125">Information</tspan> </text> <text transform="translate(32 285)" fill="#333" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17"> <tspan x="0" y="17">Proposed </tspan> <tspan x="0" y="41">Short Title</tspan> </text> <text transform="translate(32 781)" fill="#333" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17"> <tspan x="0" y="17">Background/</tspan> <tspan x="0" y="41">Rationale</tspan> </text> <path fill-opacity=".16" fill="#B9D9EB" d="M0 153h375v112H0z"/> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 153)"> <tspan x="32" y="37">Therapeutic </tspan> <tspan x="32" y="61">Area</tspan> </text> <path fill-opacity=".16" fill="#B9D9EB" d="M0 377h375v384H0z"/> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 377)"> <tspan x="32" y="37">Proposed </tspan> <tspan x="32" y="61">Authors/</tspan> <tspan x="32" y="85">Collaborators</tspan> </text> <path d="M0 1049h375v192H0zM0 1401h375v248H0zM0 1873h375v160H0z" fill="#B9D9EB" fill-opacity=".16"/> <path fill="#00254B" d="M0 1h375v64H0z"/> <path stroke="#FFF" stroke-width="1.5" stroke-linecap="square" d="M152.5 1.5v2032"/> <g fill="#FFF" font-family="SourceSansPro-Bold, Source Sans Pro" font-size="17" font-weight="bold"> <text transform="translate(32 21)"> <tspan x="0" y="17">Type</tspan> </text> <text transform="translate(32 21)"> <tspan x="148" y="17">Specifications</tspan> </text> </g> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="104" fill="#F90">•</tspan> <tspan x="188.339" y="105.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="105.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">Identification of </tspan> <tspan x="195" y="129.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> the requester</tspan> <tspan x="298.212" y="129.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="304" fill="#F90">•</tspan> <tspan x="188.339" y="305.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="305.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">Proposed or </tspan> <tspan x="195" y="329.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> anticipated title </tspan> <tspan x="195" y="353.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> if known</tspan> <tspan x="263.719" y="353.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="800" fill="#F90">•</tspan> <tspan x="188.339" y="801.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="801.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">What educational gap </tspan> <tspan x="195" y="825.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> would the publication </tspan> <tspan x="195" y="849.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> address in the existing </tspan> <tspan x="195" y="873.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> literature?</tspan> <tspan x="276.452" y="873.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1280" fill="#F90">•</tspan> <tspan x="188.339" y="1281.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1281.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">Case Study, </tspan> <tspan x="195" y="1305.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> (electronic) Medical </tspan> <tspan x="195" y="1329.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> Records, Clinical Trial, </tspan> <tspan x="195" y="1353.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> Early Access Program, </tspan> <tspan x="195" y="1377.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> Registry, etc</tspan> <tspan x="289.865" y="1377.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1440" fill="#F90">•</tspan> <tspan x="188.339" y="1441.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1441.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">What are the inclusion </tspan> <tspan x="195" y="1465.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> criteria?</tspan> <tspan x="260.625" y="1465.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1688" fill="#F90">•</tspan> <tspan x="188.339" y="1689.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1689.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">Which congress or </tspan> <tspan x="195" y="1713.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> journal is being </tspan> <tspan x="195" y="1737.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> targeted?</tspan> <tspan x="270.791" y="1737.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1912" fill="#F90">•</tspan> <tspan x="188.339" y="1913.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1913.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">Any relevant or </tspan> <tspan x="195" y="1937.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> supporting documents </tspan> <tspan x="195" y="1961.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> (quotes, etc) will </tspan> <tspan x="195" y="1985.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> need to be uploaded to </tspan> <tspan x="195" y="2009.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> complete your request</tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1768" fill="#F90">•</tspan> <tspan x="188.339" y="1769.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1769.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">Is the congress or </tspan> <tspan x="195" y="1793.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> journal in English?</tspan> <tspan x="332.722" y="1793.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1824" fill="#F90">•</tspan> <tspan x="188.339" y="1825.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1825.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">What is the submission </tspan> <tspan x="195" y="1849.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> deadline?</tspan> <tspan x="268.683" y="1849.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1496" fill="#F90">•</tspan> <tspan x="188.339" y="1497.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1497.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">Are any patient types </tspan> <tspan x="195" y="1521.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> excluded? Proposed </tspan> <tspan x="195" y="1545.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> analytical approaches?</tspan> <tspan x="366.331" y="1545.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1576" fill="#F90">•</tspan> <tspan x="188.339" y="1577.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1577.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">What is the estimated </tspan> <tspan x="195" y="1601.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> timeline for data </tspan> <tspan x="195" y="1625.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> analysis?</tspan> <tspan x="267.102" y="1625.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="904" fill="#F90">•</tspan> <tspan x="188.339" y="905.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="905.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">How might it impact </tspan> <tspan x="195" y="929.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> clinical decision–</tspan> <tspan x="195" y="953.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> making, patient </tspan> <tspan x="195" y="977.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> management, or the </tspan> <tspan x="195" y="1001.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> ability to inform future </tspan> <tspan x="195" y="1025.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> research?</tspan> <tspan x="271.318" y="1025.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1088" fill="#F90">•</tspan> <tspan x="188.339" y="1089.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1089.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">What is the </tspan> <tspan x="195" y="1113.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> hypothesis?</tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="1144" fill="#F90">•</tspan> <tspan x="188.339" y="1145.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="1145.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">What are the projected </tspan> <tspan x="195" y="1169.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> key endpoints/</tspan> <tspan x="195" y="1193.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> measures if </tspan> <tspan x="195" y="1217.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> applicable?</tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="192" fill="#F90">•</tspan> <tspan x="188.339" y="193.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="193.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">A therapeutic area </tspan> <tspan x="195" y="217.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> relevant to Alnylam </tspan> <tspan x="195" y="241.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> area(s) of interest</tspan> <tspan x="327.469" y="241.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#333"> </tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="416" fill="#F90">•</tspan> <tspan x="188.339" y="417.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="417.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">A list of potential </tspan> <tspan x="195" y="441.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> authors/collaborators</tspan> </text> <text font-family="SourceSansPro-Bold, Source Sans Pro" font-size="20" font-weight="bold" transform="translate(0 1)"> <tspan x="180" y="472" fill="#F90">•</tspan> <tspan x="188.339" y="473.18" font-family="SourceSansPro-Light, Source Sans Pro" font-size="17" font-weight="300" fill="#F90"> </tspan> <tspan x="195.122" y="473.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333">Note that, to ensure </tspan> <tspan x="195" y="497.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> compliance with local </tspan> <tspan x="195" y="521.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> laws and regulations </tspan> <tspan x="195" y="545.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> (eg, US Open </tspan> <tspan x="195" y="569.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> Payments Act, EFPIA), </tspan> <tspan x="195" y="593.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> Alnylam must track </tspan> <tspan x="195" y="617.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> and, if applicable, </tspan> <tspan x="195" y="641.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> report payments or </tspan> <tspan x="195" y="665.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> transfers of value </tspan> <tspan x="195" y="689.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> associated with certain </tspan> <tspan x="195" y="713.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> activities, including </tspan> <tspan x="195" y="737.18" font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" font-weight="normal" fill="#333"> publication support</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 1)"> <tspan x="32" y="1085">Key Research </tspan> <tspan x="32" y="1109">Question, </tspan> <tspan x="32" y="1133">Hypothesis</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 1)"> <tspan x="32" y="1277">Data Source </tspan> <tspan x="32" y="1301">for this </tspan> <tspan x="32" y="1325">Proposed </tspan> <tspan x="32" y="1349">Publication</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 1)"> <tspan x="32" y="1437">Patients, </tspan> <tspan x="32" y="1461">Methods, </tspan> <tspan x="32" y="1485">Timelines</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 1)"> <tspan x="32" y="1685">Publication </tspan> <tspan x="32" y="1709">Plan, </tspan> <tspan x="32" y="1733">Timelines</tspan> </text> <text font-family="SourceSansPro-Regular, Source Sans Pro" font-size="17" fill="#333" transform="translate(0 1)"> <tspan x="32" y="1909">Additional </tspan> <tspan x="32" y="1933">Relevant </tspan> <tspan x="32" y="1957">Details</tspan> </text> </g> </svg> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--body paragraph-id--1590 paragraph--view-mode--default"> <div class="description--component" style="width:970px; margin:auto; "> <div class="field field--name-field-body field--type-text-with-summary field--label-hidden field--item"><p> </p> <p>In alignment with Good Publication Practice (GPP3) guidelines, Alnylam does not compensate authors for time spent authoring or otherwise developing a publication or preparing for the presentation. 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