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"https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F53158243%2FExperienced_radio_guided_surgery_teams_can_successfully_perform_minimally_invasive_radio_guided_parathyroidectomy_without_intraoperative_parathyroid_hormone_%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":70077271,"identifier":"Attachment_70077271","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":53158243,"created_at":"2021-09-21T13:41:50.177-07:00","from_world_paper_id":173794133,"updated_at":"2024-11-30T06:18:30.765-08:00","_data":{"abstract":"Abstract: Minimally invasive parathyroidectomy is an accepted treatment option for primary hyperparathyroidism. The need for intraoperative parathyroid hormone assays (iPTH) to confirm adenoma removal remains controversial. We studied minimally invasive radio-...","publisher":"ingentaconnect.com","ai_title_tag":"Minimally Invasive Radio-Guided Parathyroidectomy Without iPTH","publication_date":"2006,,","publication_name":"The American …"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Experienced radio-guided surgery teams can successfully perform minimally invasive radio-guided parathyroidectomy without intraoperative parathyroid hormone …","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true,"seo_quality":null}}["work"]; window.loswp.workCoauthors = [36500216]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loginModal = {}; window.loginModal.appleClientId = 'edu.academia.applesignon'; window.userInChina = "false";</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":70077271,"attachmentType":"pdf"}"><img alt="First page of “Experienced radio-guided surgery teams can successfully perform minimally invasive radio-guided parathyroidectomy without intraoperative parathyroid hormone …”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/70077271/mini_magick20210921-21848-1stias1.png?1632257048" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/images/single_work_splash/adobe_icon.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Experienced radio-guided surgery teams can successfully perform minimally invasive radio-guided parathyroidectomy without intraoperative parathyroid hormone …</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="36500216" href="https://independent.academia.edu/BenjaminCalvo"><img alt="Profile image of Benjamin Calvo" class="ds-work-card--author-avatar" src="https://0.academia-photos.com/36500216/19174675/19120643/s65_benjamin.calvo.jpg" />Benjamin Calvo</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2006, The American …</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">6 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 53158243; 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The need for intraoperative parathyroid hormone assays (iPTH) to confirm adenoma removal remains controversial. We studied minimally invasive radio-...</p></div></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="16030151" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/16030151/140_consecutive_cases_of_minimally_invasive_radio_guided_parathyroidectomy">140 consecutive cases of minimally invasive, radio-guided parathyroidectomy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="35170300" href="https://independent.academia.edu/OdedZmora">Oded Zmora</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Surgical Endoscopy, 2003</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: The advent of highly accurate parathyroid imaging and the ever-increasing trend towards minimally invasive procedures have changed considerably the surgical approach to the patient with primary hyperparathyroidism (PHPT) caused by a single parathyroid adenoma. This study analyzes the short-and longer-term results of 140 patients who underwent minimally invasive, radio-guided parathyroidectomy. Methods: Demographic, clinical, and pre-operative imaging data, operative findings, and short-and long-term results of 140 consecutive patients operated within a 20 months period (8/1999-4/2002), were prospectively entered into a database. Immediate pre-operative sestamibi scintigraphy with skin marking of focal adenoma uptake were followed by intraoperative hand-held gamma probe for the removal of the parathyroid adenoma by unilateral minimal access surgery. Preoperative and surgical data were analyzed and correlated to outcomes, measured by success or failure to cure PHPT, associated morbidity and mortality, predictive value of localizing studies, and postoperative laboratory results in the immediate as well as long-term period. Results: 140 patients, mean age: 55.1 ± 14.1 years (range 19-88 years), female to male ratio 94:46 with PHPT proven by concomitantly elevated serum calcium and parathormone (PTH) levels, with a single adenoma identified by sestamibi single photon emission tomography (SPECT) scintigraphy and high-resolution sonography, underwent minimally invasive, radio-guided parathyroidectomy. Mean serum levels of preoperative calcium, phosphorus, and PTH were 11.6 ± 0.8 mg/dL (range 9.1-14), 3.0 ± 0.3 mg/dL, and 147.1 ± 94.3 pg/ mL (range 68-784), respectively. Overall, in 3 out of 140</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"140 consecutive cases of minimally invasive, radio-guided parathyroidectomy","attachmentId":42779469,"attachmentType":"pdf","work_url":"https://www.academia.edu/16030151/140_consecutive_cases_of_minimally_invasive_radio_guided_parathyroidectomy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/16030151/140_consecutive_cases_of_minimally_invasive_radio_guided_parathyroidectomy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="13092864" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/13092864/Minimally_invasive_radioguided_parathyroidectomy">Minimally invasive radioguided parathyroidectomy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39230931" href="https://uams.academia.edu/BrendanStack">Brendan Stack</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="41112596" href="https://independent.academia.edu/RSmith31">R. Smith</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32342283" href="https://unibo.academia.edu/StefanoFanti">Stefano Fanti</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Biomedicine & Pharmacotherapy, 2006</p><p class="ds-related-work--abstract ds2-5-body-sm">The surgical management of hyperparathyroidism has evolved over the last 20 years, transitioning from routine bilateral neck exploration to, frequently, a minimally invasive approach. Adjuncts which have made this transition possible include advancements in imaging techniques which allow the pre-operative localization of adenomatous glands, the rapid parathyroid hormone assay and the use of 99-m technetium sestamibi injections the day of surgery to allow for gamma probe detection of abnormal glands. The gamma probe can help with gland localization, which can be particularly useful in a reoperative field or with glands in ectopic locations. It is also helpful in confirming that excised tissue is abnormal parathyroid tissue, alleviating the need for frozen sections during surgery. In this chapter we discuss and review radioguided minimally invasive parathyroidectomy.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Minimally invasive radioguided parathyroidectomy","attachmentId":45676791,"attachmentType":"pdf","work_url":"https://www.academia.edu/13092864/Minimally_invasive_radioguided_parathyroidectomy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/13092864/Minimally_invasive_radioguided_parathyroidectomy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="34244274" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/34244274/Minimally_invasive_radioguided_parathyroidectomy_for_hyperparathyroidism">Minimally invasive radioguided parathyroidectomy for hyperparathyroidism</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="67328706" href="https://independent.academia.edu/HiroshiTakami">Hiroshi Takami</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of Nuclear Medicine - ANN NUCL MED, 2010</p><p class="ds-related-work--abstract ds2-5-body-sm">Clinical or subclinical hyperparathyroidism (HPT) is one of the most common endocrine disorders. In patients with HPT who meet the indications for parathyroidectomy, complete surgical resection of all hyperfunctioning parathyroid tissue is essential for the curative treatment. The conventional surgical approach is bilateral neck exploration, whereas minimally invasive parathyroidectomy has been made possible by the introduction of 99mTc-sestamibi scintigraphy for preoperative localization of parathyroid adenomas. In minimally invasive surgery, the surgeon expects some modalities that predict complete resection of all hyperfunctioning parathyroid glands. The prevalence rate of 99mTc-sestamibi scanning for single parathyroid adenoma was widely accepted as 85–95%. Moreover, the recent developing technology of semiconductor electronics has produced useful portable γ-probes. Intraoperative navigation using these devices provides the possibility of easy and definitive identification of pa...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Minimally invasive radioguided parathyroidectomy for hyperparathyroidism","attachmentId":54157042,"attachmentType":"pdf","work_url":"https://www.academia.edu/34244274/Minimally_invasive_radioguided_parathyroidectomy_for_hyperparathyroidism","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/34244274/Minimally_invasive_radioguided_parathyroidectomy_for_hyperparathyroidism"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="48699745" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/48699745/Minimally_invasive_radioguided_parathyroidectomy_an_attractive_therapeutic_option_for_elderly_patients_with_primary_hyperparathyroidism">Minimally invasive radioguided parathyroidectomy: an attractive therapeutic option for elderly patients with primary hyperparathyroidism</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="65701567" href="https://independent.academia.edu/GiulianoMariani">Giuliano Mariani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Nuclear Medicine Communications, 2004</p><p class="ds-related-work--abstract ds2-5-body-sm">The surgical management of hyperparathyroidism has evolved over the last 20 years, transitioning from routine bilateral neck exploration to, frequently, a minimally invasive approach. Adjuncts which have made this transition possible include advancements in imaging techniques which allow the pre-operative localization of adenomatous glands, the rapid parathyroid hormone assay and the use of 99-m technetium sestamibi injections the day of surgery to allow for gamma probe detection of abnormal glands. The gamma probe can help with gland localization, which can be particularly useful in a reoperative field or with glands in ectopic locations. It is also helpful in confirming that excised tissue is abnormal parathyroid tissue, alleviating the need for frozen sections during surgery. In this chapter we discuss and review radioguided minimally invasive parathyroidectomy.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Minimally invasive radioguided parathyroidectomy: an attractive therapeutic option for elderly patients with primary hyperparathyroidism","attachmentId":67195318,"attachmentType":"pdf","work_url":"https://www.academia.edu/48699745/Minimally_invasive_radioguided_parathyroidectomy_an_attractive_therapeutic_option_for_elderly_patients_with_primary_hyperparathyroidism","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/48699745/Minimally_invasive_radioguided_parathyroidectomy_an_attractive_therapeutic_option_for_elderly_patients_with_primary_hyperparathyroidism"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="67951464" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/67951464/Minimally_invasive_radioguided_parathyroidectomy_performed_for_primary_hyperparathyroidism">Minimally invasive radioguided parathyroidectomy performed for primary hyperparathyroidism</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="41403272" href="https://independent.academia.edu/GordonKauffman">Gordon Kauffman</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Otolaryngology-head and Neck Surgery, 2009</p><p class="ds-related-work--abstract ds2-5-body-sm">Operations for hyperparathyroidism (HPT) in a previously operated neck present a significant challenge and carry much higher morbidity rates than first-time operations. Our extensive experience with minimally invasive radioguided parathyroidectomy (MIRP) for first-time surgery for HPT has shown this method to be a directed approach to the offending adenoma, suggesting that the technique could be used to minimize reoperative neck surgery as well. Over an 11-month period 24 consecutive patients with primary HPT who had undergone at least one previous neck operation were referred for re-exploration. All patients underwent preoperative sestamibi scanning; 21 localized sufficiently to undergo MIRP. All patients were cured after reoperation. Eighteen patients underwent MIRP under local anesthesia as outpatients; 3 MIRPs were done under general anesthesia. Average total operative time was 44 minutes, average incision length was 3.0 cm +/- 0.2 cm. Nineteen of the procedures were completed w...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Minimally invasive radioguided parathyroidectomy performed for primary hyperparathyroidism","attachmentId":78606486,"attachmentType":"pdf","work_url":"https://www.academia.edu/67951464/Minimally_invasive_radioguided_parathyroidectomy_performed_for_primary_hyperparathyroidism","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/67951464/Minimally_invasive_radioguided_parathyroidectomy_performed_for_primary_hyperparathyroidism"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="94353226" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/94353226/Effect_of_Minimally_Invasive_Radioguided_Parathyroidectomy_on_Efficacy_Length_of_Stay_and_Costs_in_the_Management_of_Primary_Hyperparathyroidism">Effect of Minimally Invasive Radioguided Parathyroidectomy on Efficacy, Length of Stay, and Costs in the Management of Primary Hyperparathyroidism</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="252038466" href="https://independent.academia.edu/LewisBlevins3">Lewis Blevins</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of Surgery, 2000</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Effect of Minimally Invasive Radioguided Parathyroidectomy on Efficacy, Length of Stay, and Costs in the Management of Primary Hyperparathyroidism","attachmentId":96833565,"attachmentType":"pdf","work_url":"https://www.academia.edu/94353226/Effect_of_Minimally_Invasive_Radioguided_Parathyroidectomy_on_Efficacy_Length_of_Stay_and_Costs_in_the_Management_of_Primary_Hyperparathyroidism","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/94353226/Effect_of_Minimally_Invasive_Radioguided_Parathyroidectomy_on_Efficacy_Length_of_Stay_and_Costs_in_the_Management_of_Primary_Hyperparathyroidism"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="81826057" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/81826057/Minimally_Invasive_Radio_Guided_Reoperative_Surgery_with_Intraoperative_ipth_Assay_in_Primary_Hyperparathyroidism">Minimally Invasive Radio-Guided Reoperative Surgery with Intraoperative ipth Assay in Primary Hyperparathyroidism</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="146955382" href="https://independent.academia.edu/AleksanderKonturek">Aleksander Konturek</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Polish Journal of Surgery, 2008</p><p class="ds-related-work--abstract ds2-5-body-sm">The aim of the study was to present the experience of the authors in employing minimally invasive radio-guided parathyroid reoperative surgery (MIRP) combined with intraoperative iPTH assay (IOPTH) in persistent and recurrent primary hyperparathyroidism (PHP) and in patients with a history of thyroidectomy. Material and methods. A prospective analysis included the results of 12 reoperations performed employing the minimally invasive method using an intraoperative hand-held gamma camera (Gamma Finder II) following IV administration of 10 mCi 99m Tc-MIBI, combined with IOPTH (Future Diagnostics) in six patients with persistent PHP, one patient with recurrent PHP and five patients after subtotal strumectomies without planned parathyroidectomies (F : M = 10 : 2; mean age 54±10.7 years; mean preoperative iPTH concentration 233.3±80.6 ng/L). Prior to surgery, all the patients had been subjected to diagnostic imaging studies (parathyroid scintiscans, USG of the neck, in selected cases, SPECT and CT of the neck and mediastinum). The validity of MIRP and IOPTH in minimizing the extent of intraoperative neck exploration was assessed. Therapeutic results were evaluated in six-month postoperative follow-up. Results. All the patients were cured. The mean incision length was 3.5±0.5 cm. The mean operative time was 49±10 min. All the patients had a single parathyroid adenoma (in five cases-in the tracheoesophageal groove, in 3-in the retroesophageal region in the neck, in one-in the retroesophageal region in the superior posterior mediastinum, in one-in the thyrothymic ligament and in two-in the thymus). The mean ratio of adenoma to background neck radioactivity was 25.7±5.4%. The mean iPTH concentration 10 min after adenoma resection was 38.5±17.4 ng/L. No postoperative complications were noted. In six-month postoperative follow-up, all the patients demonstrated normal serum calcium values. Conclusions. MIRP has proven to be highly successful in reoperations in patients with PHP. The procedure performed using a hand-held gamma camera allows for a safe execution of a minimally invasive procedure focused on resection of a single parathyroid adenoma, eliminating the need for bilateral neck exploration, which is extensive, time-consuming and associated with a higher risk of damaging the recurrent laryngeal nerve and normal parathyroids.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Minimally Invasive Radio-Guided Reoperative Surgery with Intraoperative ipth Assay in Primary Hyperparathyroidism","attachmentId":87735617,"attachmentType":"pdf","work_url":"https://www.academia.edu/81826057/Minimally_Invasive_Radio_Guided_Reoperative_Surgery_with_Intraoperative_ipth_Assay_in_Primary_Hyperparathyroidism","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/81826057/Minimally_Invasive_Radio_Guided_Reoperative_Surgery_with_Intraoperative_ipth_Assay_in_Primary_Hyperparathyroidism"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="21546261" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/21546261/Preoperative_localization_and_radioguided_parathyroid_surgery">Preoperative localization and radioguided parathyroid surgery</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="42657443" href="https://independent.academia.edu/PucciniMarco">Marco Puccini</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003</p><p class="ds-related-work--abstract ds2-5-body-sm">Clinical or subclinical hyperparathyroidism is one of the most common endocrine disorders. Excessive secretion of parathyroid hormone is most frequently caused by an adenoma of &gt;or=1 parathyroid gland. Unsuccessful surgery with persistent hyperparathyroidism, due to inadequate preoperative or intraoperative localization, may be observed in about 10% of patients. The conventional surgical approach is bilateral neck exploration, whereas minimally invasive parathyroidectomy (MIP) has been made possible by the introduction of (99m)Tc-sestamibi scintigraphy for preoperative localization of parathyroid adenomas. In MIP, the incision is small, dissection is minimal, postoperative pain is less, and hospital stay is shorter. Localization imaging techniques include ultrasonography, CT, MRI, and scintigraphy. Parathyroid scintigraphy with (99m)Tc-sestamibi is based on longer retention of the tracer in parathyroid than in thyroid tissue. Because of the frequent association of parathyroid ade...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Preoperative localization and radioguided parathyroid surgery","attachmentId":42038549,"attachmentType":"pdf","work_url":"https://www.academia.edu/21546261/Preoperative_localization_and_radioguided_parathyroid_surgery","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/21546261/Preoperative_localization_and_radioguided_parathyroid_surgery"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="18084992" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/18084992/Minimally_Invasive_Parathyroidectomy">Minimally Invasive Parathyroidectomy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38034641" href="https://independent.academia.edu/LeeStarker">Lee Starker</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Archives of Surgery, 2011</p><p class="ds-related-work--abstract ds2-5-body-sm">Minimally invasive parathyroidectomy (MIP) for primary hyperparathyroidism can be successfully performed using preoperative sestamibi scan and intraoperative radioguidance without the need of measurement of intraoperative parathyroid hormone (PTH) levels. The purpose of our study was to review the outcomes of MIPs performed in a community hospital without measuring PTH levels intraoperatively and to demonstrate that this is an effective therapeutic modality with comparable success rates. We performed a retrospective medical record review of patients undergoing MIPs from April 1, 1998, through May 31, 2005, in a 500-bed community hospital. A total of 188 parathyroidectomies for primary hyperparathyroidism were performed by a single surgeon during the study period, 111 of which were MIPs. In this series of 111 patients, we found 2 recurrences, achieving a success rate of 98.2%. Higher preoperative PTH levels and gland weight had a direct correlation with the successful performance of MIP.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Minimally Invasive Parathyroidectomy","attachmentId":42201242,"attachmentType":"pdf","work_url":"https://www.academia.edu/18084992/Minimally_Invasive_Parathyroidectomy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/18084992/Minimally_Invasive_Parathyroidectomy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="49568146" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/49568146/Surgical_outcome_of_radioguided_parathyroidectomy_in_primary_hyperparathyroidism">Surgical outcome of radioguided parathyroidectomy in primary hyperparathyroidism</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="140493393" href="https://independent.academia.edu/dineshnalbo">dinesh nalbo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Surgery Journal</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: Focused parathyroidectomy is the adequate treatment for primary hyperparathyroidism for localised disease. Adequacy of resection is confirmed by the availability of intraoperative parathormone assay (iOPTH). In the absence of availability of iOPTH assay, the radio guided surgery is an option. The aim of this study was to evaluate the feasibility of radioguided parathyroidectomy in tertiary care centre in India and to compare the overall success rate, operative time, hospital stay and postoperative outcome between focused open and radioguided parathyroidectomy.Methods: This was a prospective study which included 30 primary hyperparathyroidism patients with a single gland disease localised on Tc99m Sesta MIBI scan. Patients were randomized into two equal groups, and they underwent focused open or radioguided parathyroidectomy. Patients were followed up for three months.Results: All patients achieved biochemical cure as evident by the normalization of serum calcium and para...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Surgical outcome of radioguided parathyroidectomy in primary hyperparathyroidism","attachmentId":67891817,"attachmentType":"pdf","work_url":"https://www.academia.edu/49568146/Surgical_outcome_of_radioguided_parathyroidectomy_in_primary_hyperparathyroidism","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/49568146/Surgical_outcome_of_radioguided_parathyroidectomy_in_primary_hyperparathyroidism"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":70077271,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":70077271,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_70077271" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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