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RCA is committed to providing a platform for discovery of high-quality articles, journals, scholars, and academic assistants by biomedical researchers, universities, hospitals, research institutions, funding agencies, librarians, publishers, and journal editors worldwide." /> </head> <body> <form method="post" action="./search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" id="form1"> <div class="aspNetHidden"> <input type="hidden" name="__EVENTTARGET" id="__EVENTTARGET" value="" /> <input type="hidden" name="__EVENTARGUMENT" id="__EVENTARGUMENT" value="" /> <input type="hidden" name="__VIEWSTATE" id="__VIEWSTATE" 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onblur="ASPx.ELostFocus('SearchTerm')" onchange="ASPx.EValueChanged('SearchTerm')" value="Pituitary-Adrenal System/metabolism" type="text" /></td> </tr> </table><script id="dxss_543298418" type="text/javascript">  </script> <span class="search-icon-container"> <a class="search-icon" href="javascript:openCategorySelector(1);"><img src="/Contents/Images/search.png" /></a> </span> </li> <li class="fl"> <div class="dxbButton_MetropolisBlue SearchButton dxbButtonSys dxbTSys" id="SearchArticle" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="SearchArticle_I" class="dxb-hb" value="Find an Article" type="submit" name="ctl00$SearchArticle" /><span class="dx-vam">Find an Article</span> </div> </div><script id="dxss_842240986" type="text/javascript">  </script> </li> </ul> <div class="cl"></div> <div class="search-menu"> <span>Find an Article (55806887)</span>   <a href="/Categories" target="_blank">Find a Category (125)</a>   <a 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class="mnavbox"> <label id="RootHolder_TotalCountText" class="total-count-text">2603</label> <br /> <label style="font-size: 14px;">(from Reference Citation Analysis)</label> <div id="RootHolder_SearchArticlePDFContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithPdf" type="checkbox" id="RootHolder_ArticlesWithPdf" class="ArticlesWithPdf" onclick="SearchArticleWithPDF();" /> <label for="ArticlesWithPdf">Article PDFs (154)</label> </div> <div id="RootHolder_SearchTCContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithTC" type="checkbox" id="RootHolder_ArticlesWithTC" class="ArticlesWithTC" onclick="SearchArticleWithTC();" /> <label for="ArticlesWithTC">Cited by ≥ 1 (1493)</label> </div> </div> <div class="mnavbar" id="SearchedNameTitle"> <div> Searched Name </div> </div> <div class="mnavbox" id="SearchedNameText"> <label id="RootHolder_SearchTermText" class="search-term-text">Pituitary-Adrenal System/metabolism</label> </div> <div 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Coenzyme Q10 and vitamin E alleviate heat stress-induced mood disturbances in male mice: Modulation of inflammatory pathways and the HPA axis. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>476</b>:115259. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39303989' target='_blank'>39303989</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115259' target='_blank'>10.1016/j.bbr.2024.115259</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115259','39303989', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(1);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115259' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/22/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.1016/j.bbr.2024.115259" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Heat stress, as an environmental stressor, can lead to temperature dysregulation and neuroinflammation, causing depression and anxiety by disrupting brain physiology and functional connectivity. This study looked at how co-enzyme Q10 (Q10) and vitamin E (Vit E), alone and together, affected heat stress-caused anxiety and depression symptoms and inflammation in male mice. Five groups were utilized in the study: control, heat stress (NS), Q10, Vit E, and the combination group (Q10+Vit E). The mice were subjected for 15 min/day to a temperature of 43°C for 14 consecutive days, followed by daily treatments for two weeks with either normal saline, Q10 (500 mg/kg), Vit E (250 mg/kg), or their combination. The forced swimming test (FST) and tail suspension test (TST) were employed to evaluate despair behavior, whereas the elevated plus maze (EPM) and open field test (OFT) were used to assess anxious behaviors. Subsequently, the animals were sacrificed, and serum corticosterone levels, protein expression of inflammasome-related proteins, and hsp70 gene expression were evaluated in the prefrontal cortex (PFC). The study revealed that treatment with Vit E and Q10, alone or together, provided anxiolytic and antidepressant effects in the heat-stress-subjected animals. Also, giving Vit E and Q10 alone or together greatly lowered serum corticosterone levels. In the PFC, they also lowered the levels of hsp70 mRNA and NF-κB, caspase 1, NLRP3, and IL-1β proteins. It is speculated that treatment with Q10 and Vit E can attenuate heat stress-associated anxious and depressive responses by inhibiting the inflammatory pathways and modulating the hypothalamus-pituitary-adrenal axis. </div> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticosterone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticosterone</a></li><li><a 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Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HSP70+Heat-Shock+Proteins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HSP70 Heat-Shock Proteins/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(1);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow2"> <td style="min-width: 40px; text-align: center;"> 2 </td> <td> <div id="citation2" class="article-citation"> <b>Marsh JS</b>, Teixeira C, Gavade S, Johnston C, Baranwal S, Snyder CN, Chang CL, Yang S, Spencer-Segal JL. Ventral subiculum control of avoidance behavior and hypothalamic-pituitary-adrenal axis reactivity via the bed nucleus of the stria terminalis in male and female mice - ISPNE 2024 Dirk Helhammer Award. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2025;<b>171</b>:107229. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39504606' target='_blank'>39504606</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107229' target='_blank'>10.1016/j.psyneuen.2024.107229</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107229','39504606', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(2);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107229' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/08/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.1016/j.psyneuen.2024.107229" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Avoidance or anxiety-like behavior is accompanied by corresponding changes in hypothalamic-pituitary-adrenal (HPA) axis activation. The underlying neural circuitry for this coordinated behavioral and neuroendocrine control is not well established. Prior studies pointed to a neural projection from the ventral subiculum (vSub) to the bed nucleus of the stria terminalis (BNST) that can inhibit the HPA axis response to stress. Here, we used chemogenetics to investigate the role of vSub neurons and their projection to the anterior BNST (aBNST) in avoidance behavior and the accompanying corticosterone response in male and female mice. Surprisingly, we found that chemogenetic activation of ventral subiculum neurons increased the HPA axis response to an open field test in male and female mice, which was also seen with selective activation of vSub neurons projecting to the anterior BNST (vSub-aBNST neurons). On the other hand, VSub neuron and vSub-aBNST neuron activation had different effects on avoidance behavior, suggesting that the behavioral role of the VSub is variable and is dissociable from its neuroendocrine effects. In conclusion, our results reveal a surprising and novel role for the ventral subiculum in HPA axis activation via the anterior BNST. We also show that, like the ventral hippocampus, ventral subiculum neurons can increase or decrease avoidance behavior depending on their downstream projection. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Avoidance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Avoidance</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucocorticoid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucocorticoid</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HPA+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HPA axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subiculum%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subiculum</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Septal+Nuclei%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Septal Nuclei/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Septal+Nuclei%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Septal Nuclei/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Avoidance+Learning%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Avoidance Learning/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behavior%2c+Animal%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behavior, Animal/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neural+Pathways%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neural Pathways/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li></ul> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Ping EY</b>, Herriot H, Iacono V, Serravalle L, Ellenbogen MA. Hypothalamic-pituitary-adrenal axis function in the offspring of parents with bipolar disorder and the impact of the family environment: A pilot study of the Reducing Unwanted Stress in the Home (RUSH) prevention program. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2025;<b>171</b>:107182. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39357242' target='_blank'>39357242</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107182' target='_blank'>10.1016/j.psyneuen.2024.107182</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107182','39357242', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(3);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107182' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/14/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1016/j.psyneuen.2024.107182" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">The home environment of offspring of parents with bipolar disorder (OBD) has been characterized by high levels of stress and disorganization, which may impact development of the hypothalamic-pituitary-adrenal (HPA) axis and their subsequent risk for affective disorders. The present study examined the effects of a family-based preventative intervention on the OBD's HPA axis functioning and whether intervention-related changes in the home environment might have driven change in the HPA axis. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Fifty-five children (6-11 years) were recruited from families having a parent with bipolar disorder (n=26) or families having two parents with no current mental disorders (n=29). Only those families with a parent having bipolar disorder participated in the preventative intervention. Both groups completed assessments at baseline, post-prevention, 3-, and 6-months post-prevention. At each assessment, family organization, control, cohesion, conflict, and expressiveness, in addition to childhood internalizing problems, were measured, and offspring saliva samples were collected across two consecutive days. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Hierarchical Linear Modelling found no significant differences in HPA axis functioning between groups at baseline or across time. Improvements in family organization, however, were associated with elevations in participants' cortisol awakening response (CAR; p =.004) and total daily output (p =.023), and a steepening of their diurnal slope (p =.003) across time. Similar findings were obtained for family cohesion with respect to CAR (p <.001) and, to a lesser degree, diurnal slope (p =.064). </div><div class="abstract-label">DISCUSSION</div><div class="abstract-content">HPA axis functioning did not differ between the OBD and healthy controls at baseline or in response to the preventative intervention. However, intervention-related improvements in family organization and, to a lesser degree, cohesion, were associated with adaptive changes in HPA functioning over time. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bipolar+disorder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bipolar disorder</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol+awakening+response%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol awakening response</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HPA+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HPA axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Offspring%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Offspring</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prevention%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prevention</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pilot+Projects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pilot Projects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Child%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Child</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bipolar+Disorder%2fprevention+%26amp%3b+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bipolar Disorder/prevention & control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bipolar+Disorder%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bipolar Disorder/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Child+of+Impaired+Parents%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Child of Impaired Parents/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Saliva%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Saliva/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Parents%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Parents/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Family%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Family/psychology</a></li></ul> <a href="javascript:ShowArticleMeSH(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(3);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow4"> <td style="min-width: 40px; text-align: center;"> 4 </td> <td> <div id="citation4" class="article-citation"> <b>Silke O</b>, Simon SG, Sosnowski DW, Johnson SB, Granger DA, Riis JL. Patterns of stress-related change in salivary alpha-amylase and cortisol among young children: Associations with maternal psychosocial risk factors. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2025;<b>171</b>:107221. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39476604' target='_blank'>39476604</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107221' target='_blank'>10.1016/j.psyneuen.2024.107221</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107221','39476604', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(4);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(4);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107221' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/18/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.1016/j.psyneuen.2024.107221" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Our understanding of associations between family-level risk factors and children's stress physiology is largely derived from studies that apply "mean-based" rather than "person-level" approaches. In this study, we employed group-based trajectory modeling, a person-centered approach, to identify children with similar patterns of stress-related sympathetic nervous system (SNS) and hypothalamic-pituitary-adrenal (HPA) axis activation, and explored associations between these patterns and maternal psychosocial risk. Participants were five-year-old children (N=147; 52 % female; 62 % Black/African American) and their mothers. Children's saliva was sampled four times during a series of emotional stressor tasks and later assayed for sAA and cortisol, indexing SNS and HPA activity, respectively. Mothers reported their depressive and anxiety symptoms, parenting stress, financial stress, and income. Results revealed two task-related patterns of change for sAA (Low-Stable vs. High-Increasing) and cortisol (Low-Stable vs. High-Decreasing) concentrations. Children from families with lower income were more likely to exhibit the High-Increasing SNS pattern, [OR=0.78, 95 % CI (0.64, 0.95)], and children of mothers reporting more anxiety symptoms [OR=1.06, 95 % CI (1.00, 1.12)] and more parenting stress [OR=1.04, 95 % CI (1.00, 1.07)] were more likely to show the High-Decreasing HPA pattern. Implications of this person-centered approach and findings for advancing our understanding of associations between family-level risk factors and children's stress physiology are discussed. </div> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Group-based+trajectory+modeling%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Group-based trajectory modeling</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamic-pituitary-adrenal+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamic-pituitary-adrenal axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Saliva%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Saliva</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sympathetic+nervous+system%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sympathetic nervous system</a></li></ul> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/analysis</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mother-Child+Relations%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mother-Child Relations/psychology</a></li></ul> <a href="javascript:ShowArticleMeSH(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Uy JP</b>, Shin K, Buthmann JL, Kircanski K, LeMoult J, Berens AE, Gotlib IH. Exposure to diesel-related particulate matter, cortisol stress responsivity, and depressive symptoms in adolescents. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2025;<b>171</b>:107214. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39426039' target='_blank'>39426039</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568899' target='_blank'>PMC11568899</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107214' target='_blank'>10.1016/j.psyneuen.2024.107214</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107214','39426039', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(5);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(5);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107214' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/21/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.1016/j.psyneuen.2024.107214" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Exposure to air pollution is associated with higher risk for psychopathology; however, the mechanisms underlying this association are not clear. Dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis in response to stress has been implicated in depression. Here, we estimated annual exposure to particulate matter (PM) from diesel emissions in 170 9- to 15-year-old adolescents (56 % female) using their residential addresses and data from nearby monitoring sites. We obtained salivary cortisol samples from participants while they completed a social stress task and calculated area under the curve with respect to ground (AUCg) and with respect to increase (AUCi) in order to assess cortisol responsivity during stress. Participants also reported on their depressive symptoms and sleep disturbances. Greater exposure to diesel PM was associated with lower cortisol output (AUCg) during stress, which was associated with higher depressive symptoms, particularly for adolescents with more sleep disturbances. Importantly, these effects were independent of household and neighborhood socioeconomic disadvantage and exposure to early adversity. Thus, HPA-axis dysfunction may be one mechanism through which environmental pollutants affect adolescents' mental health. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adolescents%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adolescents</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pollution%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pollution</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress+reactivity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress reactivity</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Particulate+Matter%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Particulate Matter/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+Exposure%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental Exposure/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Air+Pollution%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Air Pollution/adverse effects</a></li></ul> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIMH+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">F32 MH135657 NIMH NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIMH+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R37 MH101495 NIMH NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>Jopling E</b>, Tracy A, LeMoult J. Attention to social threat predicts diurnal cortisol dynamics during the high school transition. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2025;<b>171</b>:107226. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39481302' target='_blank'>39481302</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107226' target='_blank'>10.1016/j.psyneuen.2024.107226</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107226','39481302', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(6);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(6);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107226' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/02/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1016/j.psyneuen.2024.107226" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Adolescence is a developmental period marked by significant social shifts accompanied by concurrent changes across biological, cognitive, and emotional domains. Within adolescence, the high school transition is a pivotal time for youth that is ripe with opportunities yet has the potential to disrupt functioning. An increasingly sophisticated understanding of health and developmental biology indicates that the hypothalamic-pituitary-adrenal (HPA) axis plays an important role in transducing social experiences into physiological changes that have long-term impacts on health and wellbeing. There is reason to believe that attentional biases to social threat could impact cortisol, a steroid hormone indexing activity of the HPA axis, during the high school transition. The present study examined associations between attentional biases to socially threatening stimuli, measured using the Affective Posner paradigm, and components of the diurnal cortisol rhythm among youth across the first two days of high school. Participants included 67 youth (N = 504 saliva samples) with a mean age of 12.86 years and a relatively equal split with regard to both sex assigned at birth and gender identity (54 % male; 54 % boys). Findings build upon and extend previous work by demonstrating that greater attentional engagement bias to socially threatening stimuli is associated with a pattern of greater diurnal HPA axis reactivity across the first two days of the high school transition, as evidenced by a steeper cortisol awakening response and a steeper diurnal cortisol slope. This work extends our understanding of the mechanisms through which stress relates to wellbeing in youth by embedding biological development in the life course. Clinically, this work has the potential to inform interventions to protect youth against the biological embedding of stress by identifying a theoretically driven, socio-contextually relevant risk factor to be attenuated - namely, attentional bias to threat. </div> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adolescence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adolescence</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Attention+Bias%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Attention Bias</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22High+School+Transition%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">High School Transition</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; 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padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Yan Q</b>. Personality and Psychoneuroimmunology: A Systems Biology Perspective. <em class='incite-journal-name' onclick='ShowInCiteJournal(169595);'>Methods Mol Biol</em> 2025;<b>2868</b>:15-36. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39546223' target='_blank'>39546223</a> DOI: <a href='https://dx.doi.org/10.1007/978-1-0716-4200-9_2' target='_blank'>10.1007/978-1-0716-4200-9_2</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/978-1-0716-4200-9_2','39546223', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(7);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/978-1-0716-4200-9_2' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169595);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/17/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.1007/978-1-0716-4200-9_2" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Research in psychoneuroimmunology (PNI) underscores the intricate connections within the "whole mind-body system." Personality plays a pivotal role, with specific traits linked to stress influencing neural behavior and psychophysiological disorders. Gene expression networks associated with personality affect neuronal plasticity, epigenetic processes, and adaptive behaviors, highlighting the importance of systems biology mechanisms. Systemic inflammation correlates with key personality traits. Understanding the roles of inflammatory and oxidative biomarkers in personality traits and disorders can help identify diagnostic and therapeutic targets for various diseases. Neurobiological features contribute to our understanding of personality disorders and related conditions. Personality traits are linked to distributed neuroendocrine networks, particularly the hypothalamic-pituitary-adrenal (HPA) axis, rather than localized brain areas. Correlations have also been identified between personality traits and thyroid hormones. Disrupted hypothalamic-pituitary-thyroid (HPT) axis functions may be associated with disease severity, depression, and distress, highlighting the need for comprehensive endocrinological and psychopathological evaluations. The gut-brain axis influences personality traits, emotions, stress, and social behaviors. Altered gut microbiota is common in psychiatric conditions, suggesting potential treatments targeting the microbiota. Chronic stress impacts cognitive functions and correlates with personality and mental health, emphasizing the need for comprehensive, multi-dimensional patient profiles for effective prevention and therapy. A biopsychosocial model integrating personality traits will advance personalized and systems medicine. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gut-brain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gut-brain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamic-pituitary-adrenal+(HPA)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamic-pituitary-adrenal (HPA)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamic-pituitary-thyroid+(HPT)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamic-pituitary-thyroid (HPT)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22InflammationInflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">InflammationInflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Personality+traitsPersonalitypersonality+traits%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Personality traitsPersonalitypersonality traits</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Personalized+medicine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Personalized medicine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychoneuroimmunology+(PNI)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychoneuroimmunology (PNI)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Systems+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Systems biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Systems+medicine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Systems medicine</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Systems+Biology%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Systems Biology/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychoneuroimmunology%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychoneuroimmunology/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Personality%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Personality</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gastrointestinal+Microbiome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gastrointestinal Microbiome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-Gut+Axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-Gut Axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/immunology</a></li></ul> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Chen YM</b>, Huang J, Fan H, Li WY, Shi TS, Zhao J, Wang CN, Chen WJ, Zhu BL, Qian JJ, Guan W, Jiang B. QRFP and GPR103 in the paraventricular nucleus play a role in chronic stress-induced depressive-like symptomatology by enhancing the hypothalamic-pituitary-adrenal axis. <em class='incite-journal-name' onclick='ShowInCiteJournal(17736);'>Neuropharmacology</em> 2025;<b>262</b>:110198. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39442911' target='_blank'>39442911</a> DOI: <a href='https://dx.doi.org/10.1016/j.neuropharm.2024.110198' target='_blank'>10.1016/j.neuropharm.2024.110198</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.neuropharm.2024.110198','39442911', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(8);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.neuropharm.2024.110198' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17736);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/25/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.1016/j.neuropharm.2024.110198" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis during chronic stress is essential for depression neurobiology. As the latest member of the RFamide peptide family in mammals, pyroglutamylated RFamide peptide (QRFP) is closely implicated in neuroendocrine maintenance by activating G-protein-coupled receptor 103 (GPR103). We hypothesized that QRFP and GPR103 might contribute to chronic stress-induced depression by promoting corticotropin-releasing hormone (CRH) release from neurons in the paraventricular nucleus (PVN), and various methods were employed in this study, with male C57BL/6J mice adopted as the experimental subjects. Chronic stress induced not only depression-like behaviors but also significant enhancement in QRFP and GPR103 in the PVN. Genetic overexpression of QRFP/GPR103 and stereotactic infusion of QRFP-26/QRFP-43 peptide in the PVN all mimicked chronic stress that induced various depression-like phenotypes in naïve mice, and this was mediated by promoting CRH biosynthesis and HPA activity. In contrast, genetic knockdown of QRFP/GPR103 in the PVN produced notable antidepressant-like effects in mice exposed to chronic stress. Furthermore, genetic knockout of QRFP also protected against chronic stress in mice. In addition, both the C-terminal biological region of QRFP and the downstream PKA/PKC-CREB signaling coupled to GPR103 stimulation underlie the role of QRFP and GPR103 in depression. Collectively, QRFP and GPR103 in PVN neurons could be viable targets for novel antidepressants. </div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticotropin-releasing+hormone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticotropin-releasing hormone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22G-protein-coupled+receptor+103%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">G-protein-coupled receptor 103</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamic-pituitary-adrenal+(HPA)+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamic-pituitary-adrenal (HPA) axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pyroglutamylated+RFamide+peptide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pyroglutamylated RFamide peptide</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Paraventricular+Hypothalamic+Nucleus%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Paraventricular Hypothalamic Nucleus/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Paraventricular+Hypothalamic+Nucleus%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Paraventricular Hypothalamic Nucleus/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Receptors%2c+G-Protein-Coupled%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Receptors, G-Protein-Coupled/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Receptors%2c+G-Protein-Coupled%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Receptors, G-Protein-Coupled/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticotropin-Releasing+Hormone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticotropin-Releasing Hormone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuropeptides%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuropeptides/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intercellular+Signaling+Peptides+and+Proteins%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intercellular Signaling Peptides and Proteins</a></li></ul> <a href="javascript:ShowArticleMeSH(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Yan Q</b>. Personality, Aging, and Alzheimer's Disease: Implications for Psychoneuroimmunology and Personalized Medicine. <em class='incite-journal-name' onclick='ShowInCiteJournal(169595);'>Methods Mol Biol</em> 2025;<b>2868</b>:37-48. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39546224' target='_blank'>39546224</a> DOI: <a href='https://dx.doi.org/10.1007/978-1-0716-4200-9_3' target='_blank'>10.1007/978-1-0716-4200-9_3</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/978-1-0716-4200-9_3','39546224', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/978-1-0716-4200-9_3' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169595);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/17/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.1007/978-1-0716-4200-9_3" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Psychoneuroimmunology (PNI) advancements may revolutionize personalized medicine by identifying systemic biomarkers that enhance diagnosis and treatment. Inflammatory pathways connect personality traits with cognitive performance, aging-related disorders, and mortality risks. Studies have demonstrated the critical interactions between personality and various biological systems like the hypothalamic-pituitary-adrenal (HPA) axis. The gut-brain axis also affects behaviors and psychological states in older adults, with specific gut microbiota influencing cognition, mood, and personality. These findings underscore the practical implications of understanding personality-biology interactions. They can support preventive and personalized medicine for aging-associated disorders. Specifically, personality changes are prevalent in Alzheimer's disease (AD) patients, impacting clinical management and caregiver stress. Non-cognitive factors, such as personality traits and psychiatric symptoms, may serve as early markers of AD. Traits like high Neuroticism and low Openness can predict initial AD stages, often before a formal diagnosis. Personality alterations in AD are also linked to cerebrospinal fluid (CSF) and vascular imaging biomarkers, which can track AD pathology and serve as predictors. Dynamic personality assessment can aid in timely diagnosis, monitoring progression, and evaluating treatments of AD. Understanding personality traits is crucial for predicting burnout, lifespan, and intervention success. Integrating personality and PNI biomarkers into patient profiles will support the development of personalized and systems medicine. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alzheimer%e2%80%99s+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alzheimer’s disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dementia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dementia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gut-brain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gut-brain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamic-pituitary-adrenal+(HPA)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamic-pituitary-adrenal (HPA)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22InflammationInflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">InflammationInflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Personality+traitsPersonalitypersonality+traits%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Personality traitsPersonalitypersonality traits</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Personalized+medicine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Personalized medicine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychoneuroimmunology+(PNI)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychoneuroimmunology (PNI)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Systems+biology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Systems biology</a></li></ul> <a href="javascript:ShowArticleKeywords(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alzheimer+Disease%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alzheimer Disease/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alzheimer+Disease%2fimmunology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alzheimer Disease/immunology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Precision+Medicine%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Precision Medicine/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychoneuroimmunology%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychoneuroimmunology/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Personality%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Personality</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biomarkers%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biomarkers</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-Gut+Axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-Gut Axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(9);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow10"> <td style="min-width: 40px; text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Watanabe M</b>, Yoshiike K, Miki E, Kuroki K. 3,5-Dihydroxy-4-methoxybenzyl alcohol, a novel antioxidant isolated from oyster meat, inhibits the hypothalamus-pituitary-adrenal axis to regulate the stress response. <em class='incite-journal-name' onclick='ShowInCiteJournal(4013);'>Brain Res</em> 2024;<b>1845</b>:149290. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39461666' target='_blank'>39461666</a> DOI: <a href='https://dx.doi.org/10.1016/j.brainres.2024.149290' target='_blank'>10.1016/j.brainres.2024.149290</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.brainres.2024.149290','39461666', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(10);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(10);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.brainres.2024.149290' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4013);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/29/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.1016/j.brainres.2024.149290" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Antioxidants that can scavenge reactive oxygen in the brain and inhibit hyperactivity of the HPA axis are desirable. </div><div class="abstract-label">AIMS</div><div class="abstract-content">We investigated the cerebral translocation of the antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol (DHMBA) and the effects of DHMBA administration on the hypothalamus-pituitary-adrenal (HPA) axis in stress-loaded rats. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Experiment 1: Plasma and brain DHMBA concentrations were measured over time after oral DHMBA administration to male B6 mice. Experiment 2: Female Wistar Imamichi rats were used. The normal group was not subjected to stress. The stress, DHMBA, and vitamin E groups were subjected to individual and overcrowding stress. Brain and hippocampal 8-hydroxy-2'-deoxyguanosine levels, hippocampal glucocorticoid receptor-α levels, plasma corticosterone levels and RNA levels of glutathione peroxidase 4, catalase, and glutathione reductase in the hippocampus were measured. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">In Experiment 1, DHMBA was not detected in the plasma or brain before DHMBA administration but was detected in both after administration. In Experiment 2, brain and hippocampal 8-hydroxy-2'-deoxyguanosine levels and plasma corticosterone levels were significantly lower in the DHMBA than in the stress group. Glucocorticoid receptor-α levels were higher in the DHMBA than in the stress group. DHMBA increased RNA levels of antioxidant enzymes in the hippocampus. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">DHMBA was translocated to the brain after administration. DHMBA administration decreased 8-hydroxy-2'-deoxyguanosine levels in the brain and hippocampus, increased hippocampal glucocorticoid receptor-α levels, and decreased the plasma corticosterone concentration, suggesting that DHMBA inhibits hyperactivity of the HPA axis. Nrf2 pathway activity induced by DHMBA resulted in increased antioxidant enzyme levels in the hippocampus. </div> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%223%2c5-dihydroxy-4-methoxybenzyl+alcohol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">3,5-dihydroxy-4-methoxybenzyl alcohol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antioxidants%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antioxidants</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucocorticoid+receptor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucocorticoid receptor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamus%e2%80%93pituitary%e2%80%93adrenal+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamus–pituitary–adrenal axis</a></li></ul> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antioxidants%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antioxidants/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antioxidants%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antioxidants/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Wistar%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Wistar</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticosterone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticosterone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Receptors%2c+Glucocorticoid%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Receptors, Glucocorticoid/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/drug effects</a></li></ul> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Xu DW</b>, Li WY, Shi TS, Wang CN, Zhou SY, Liu W, Chen WJ, Zhu BL, Fei H, Cheng DD, Cui ZM, Jiang B. MiR-184-3p in the paraventricular nucleus participates in the neurobiology of depression via regulation of the hypothalamus-pituitary-adrenal axis. <em class='incite-journal-name' onclick='ShowInCiteJournal(17736);'>Neuropharmacology</em> 2024;<b>260</b>:110129. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39179173' target='_blank'>39179173</a> DOI: <a href='https://dx.doi.org/10.1016/j.neuropharm.2024.110129' target='_blank'>10.1016/j.neuropharm.2024.110129</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.neuropharm.2024.110129','39179173', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(11);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(11);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.neuropharm.2024.110129' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17736);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/26/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.1016/j.neuropharm.2024.110129" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis during chronic stress is essential for the pathogenesis of depression, and increased activity of cAMP response element binding protein (CREB)-regulated transcription co-activator 1 (CRTC1) in the paraventricular nucleus (PVN) plays a critical role. As a well-investigated microRNA (miRNA), miR-184 has two forms, miR-184-3p and miR-184-5p. Recently, miRNAs target genes predictive analysis and dual-luciferase reporter assays identified an inhibitory role of miR-184-3p on CRTC1 expression. Therefore, we speculated that miR-184-3p regulation was responsible for the effects of chronic stress on CRTC1 in the PVN. Various methods, including the chronic social defeat stress (CSDS) model of depression, behavioral tests, Western blotting, co-immunoprecipitation (Co-IP), quantitative real-time reverse transcription PCR (qRT-PCR), immunofluorescence, and adeno-associated virus (AAV)-mediated gene transfer, were used. CSDS evidently downregulated the level of miR-184-3p, but not miR-184-5p, in the PVN. Genetic knockdown and pharmacological inhibition of miR-184-3p in the PVN induced various depressive-like symptoms (e.g., abnormal behaviors, HPA hyperactivity, enhanced CRTC1 function in PVN neurons, downregulation of hippocampal neurogenesis, and decreased brain-derived neurotrophic factor (BDNF) signaling) in naïve male C57BL/6J mice. In contrast, genetic overexpression and pharmacological activation of miR-184-3p in the PVN produced significant beneficial effects against CSDS. MiR-184-3p in the PVN was necessary for the antidepressant actions of two well-known SSRIs, fluoxetine and paroxetine. Collectively. miR-184-3p was also implicated in the neurobiology of depression and may be a viable target for novel antidepressants. </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CREB-Regulated+transcription+co-activator+1+(CRTC1)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CREB-Regulated transcription co-activator 1 (CRTC1)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+social+defeat+stress+(CSDS)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic social defeat stress (CSDS)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamic-pituitary-adrenal+(HPA)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamic-pituitary-adrenal (HPA)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Paraventricular+nucleus+(PVN)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Paraventricular nucleus (PVN)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22miR-184-3p%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">miR-184-3p</a></li></ul> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-Derived+Neurotrophic+Factor%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-Derived Neurotrophic Factor/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-Derived+Neurotrophic+Factor%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-Derived Neurotrophic Factor/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MicroRNAs%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MicroRNAs/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MicroRNAs%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MicroRNAs/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Paraventricular+Hypothalamic+Nucleus%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Paraventricular Hypothalamic Nucleus/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Social+Defeat%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Social Defeat</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcription+Factors%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcription Factors/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcription+Factors%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcription Factors/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(11);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow12"> <td style="min-width: 40px; text-align: center;"> 12 </td> <td> <div id="citation12" class="article-citation"> <b>Perez-Caballero L</b>, Guillot de Suduiraut I, Romero LR, Grosse J, Sandi C, Andero R. Corticosterone administration immediately after peripuberty stress exposure does not prevent protracted stress-induced behavioral alterations. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2024;<b>170</b>:107164. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39146600' target='_blank'>39146600</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107164' target='_blank'>10.1016/j.psyneuen.2024.107164</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107164','39146600', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(12);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107164' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/17/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.1016/j.psyneuen.2024.107164" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Stress-related disorders are commonly associated with abnormalities in hypothalamic-pituitary-adrenal (HPA) axis activity. Preliminary studies with cortisol administration in the aftermath of trauma suggest that this HPA axis hormone can potentially prevent maladaptive behavioral and biological stress responses. However, the efficacy of glucocorticoid administration during the peripuberty period has not been tested yet, although this lifetime is a critical time window in brain development and is highly sensitive to the harmful effects of stress. To further examine the short and long-lasting impact of glucocorticoids treatment given during the post-peripubertal stress period, the present study utilized a rat model of peripubertal stress-induced psychopathology and animals were subjected to a battery of tests to assess anxiety-like behaviors, exploratory behavior and reactivity to novelty at late adolescence and sociability, anhedonia and stress coping behaviors at adulthood. All the experiments were performed in males and females to evaluate the potential behavioral sex differences. Overall, our results demonstrated that rats exposed to peripubertal stress show decreased sociability in adulthood without differences in anxiety and depression-like behaviors. Moreover, this study shows that the administration of corticosterone after stress exposure at peripuberty does not prevent stress-induced behavioral alterations. However, we observed that some stress-induced behavioural alterations and corticosterone responses are sex-specific. Thus, the data obtained highlight that delineating sex differences in stress-related studies may ultimately contribute to the development of effective therapeutic interventions for each sex. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticosterone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticosterone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HPA+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HPA axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Peripubertal+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Peripubertal stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Preventing+treatment%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Preventing treatment</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex+differences%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex differences</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress</a></li></ul> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticosterone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticosterone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anhedonia%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anhedonia/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Wistar%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Wistar</a></li></ul> <a href="javascript:ShowArticleMeSH(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(12);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Anderson AM</b>, Sherman J, Fitzpatrick MM, Browning C, Kertes DA, Mackos A, Pickler RH, Smith L, Ford JL. Associations between adolescent perceived loneliness and hair cortisol concentration. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2024;<b>170</b>:107184. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39332136' target='_blank'>39332136</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107184' target='_blank'>10.1016/j.psyneuen.2024.107184</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107184','39332136', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(13);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107184' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/29/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.1016/j.psyneuen.2024.107184" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">INTRODUCTION</div><div class="abstract-content">Adolescents experience high levels of loneliness, which is linked to poor health in adulthood. Loneliness may contribute to poor health through chronic dysregulation of the hypothalamic-pituitary-adrenal axis. In this analysis, we examined the associations between survey- and ecological momentary assessment (EMA)-based measures of loneliness and hair cortisol concentrations (HCC) in a sample of 1102 adolescents and assessed sex differences in this relationship. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Data came from wave 1 of the Adolescent Health and Development in Context study. We conducted a series of multivariable linear regression models to examine the associations between loneliness and HCC. Models were adjusted for adolescent and caregiver demographics, adolescent clinical factors, adolescent hair care practices, and adolescent lifetime mental health diagnosis and current psychotropic medication use. An interaction term between sex and loneliness was added to assess for effect moderation. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">In our sample, the mean HCC was 1.35 pg/mg (SD=1.1). The mean for the unstandardized survey loneliness measure was 1.79 (SD=0.79) for the total analytic sample. The unstandardized mean for the EMA loneliness measure was - 0.02 (SD=2.1) for the total analytic sample. In model one testing the bivariate linear relationship between loneliness and HCC, higher loneliness via survey and EMA measures was associated with lower HCC (Survey: b= - 0.10, SE=0.03, p=.004; EMA: b= - 0.09, SE=0.03, p=.005). In model two, higher loneliness remained significantly associated with lower HCC (Survey: b= - 0.07, SE=0.03, p=.023; EMA: b= - 0.07, SE=0.03, p=.037), after controlling for the following covariates: sociodemographic factors, pubertal development and BMI, corticosteroid use, hair care practices, season of collection and assayed hair length. In model 3, youth lifetime mental health diagnosis and current psychotropic medication use were added into the regression model, and higher loneliness remained significantly associated with lower HCC (Survey: b= - 0.07, SE=0.03, p=.029; EMA: b= - 0.07, SE=0.03, p=.039). There was no effect modification by sex (Survey: b=0.04, SE=0.06, p=.552; EMA: b= - 0.01, SE=0.06, p=.843). </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">In our analysis, both survey- and EMA-reported loneliness measures were associated with lower HCC. No evidence of an interaction between sex and loneliness was observed. Future research is needed to validate these findings and investigate longitudinal relationships among adolescent loneliness, stress physiology, and downstream health sequelae. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adolescence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adolescence</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HPA-axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HPA-axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Loneliness%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Loneliness</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress+physiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress physiology</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adolescent%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adolescent</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Loneliness%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Loneliness/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hair%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hair/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex Factors</a></li></ul> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>Vasaruchapong T</b>, Noiphrom J, Chaiyabutr N, Thammacharoen S. Behavioral and hormonal responses in the defensive repertoire during provocation in captive monocled cobra (Naja kaouthia). <em class='incite-journal-name' onclick='ShowInCiteJournal(19259);'>Physiol Behav</em> 2024;<b>287</b>:114689. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39255867' target='_blank'>39255867</a> DOI: <a href='https://dx.doi.org/10.1016/j.physbeh.2024.114689' target='_blank'>10.1016/j.physbeh.2024.114689</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.physbeh.2024.114689','39255867', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(14);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.physbeh.2024.114689' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19259);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/12/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.1016/j.physbeh.2024.114689" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The hooding behavior exhibited by cobras is a distinct defensive mechanism against predators, encompassing both visual and auditory displays. This behavior can be triggered by natural predators or humans. Considering that human provocation may potentially stimulate the hypothalamic-pituitary-adrenal (HPA) axis, the present study aimed to determine the pattern of the HPA axis response following human provocation-induced hooding behavior (PV) and provide a detailed analysis of the behavioral PV displays. Our primary hypothesis was that a 5-minute PV could activate the HPA axis to a degree comparable to that in the restraint-induced stress model (RS). The PV, RS-1 (1-minute), and RS-5 (5-minute) restraint models indeed activated the HPA axis. However, the pattern of plasma corticosteroid (CORT), but not arginine vasotocin, in the PV group differed from that in the RS-1 and RS-2 groups. The present study revealed the behavioral components of the PV. The first component appeared to be related to an increase in apparent size that is an intimidation display, while the second hissing and striking component consisted of a bluff charge. Moreover, no correlation was observed between the pattern of plasma CORT and any specific PV display. Finally, the body temperature (Tb) of cobras from RS-5 gradually increased, while the Tb of cobras from PV (5 min) remained unchanged. In conclusion, the activation of the HPA axis emerges as the main physiological response after human provocation. Within 5 min of provocation, the cobras' hooding behavior comprised two display components that were not related to the pattern of plasma CORT. </div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Arginine+vasotocin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Arginine vasotocin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Body+temperature%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Body temperature</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticosterone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticosterone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Defensive+behavior%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Defensive behavior</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Monocled+cobra%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Monocled cobra</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Restraint%2c+Physical%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Restraint, Physical</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behavior%2c+Animal%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behavior, Animal/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/blood</a></li></ul> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>Bindellini D</b>, Michelet R, Aulin LBS, Melin J, Neumann U, Blankenstein O, Huisinga W, Whitaker MJ, Ross R, Kloft C. A quantitative modeling framework to understand the physiology of the hypothalamic-pituitary-adrenal axis and interaction with cortisol replacement therapy. <em class='incite-journal-name' onclick='ShowInCiteJournal(14933);'>J Pharmacokinet Pharmacodyn</em> 2024;<b>51</b>:809-824. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38977635' target='_blank'>38977635</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11579075' target='_blank'>PMC11579075</a> DOI: <a href='https://dx.doi.org/10.1007/s10928-024-09934-7' target='_blank'>10.1007/s10928-024-09934-7</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s10928-024-09934-7','38977635', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(15);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(15);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s10928-024-09934-7' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(14933);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.1007/s10928-024-09934-7" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Congenital adrenal hyperplasia (CAH) is characterized by impaired adrenal cortisol production. Hydrocortisone (synthetic cortisol) is the drug-of-choice for cortisol replacement therapy, aiming to mimic physiological cortisol circadian rhythm. The hypothalamic-pituitary-adrenal (HPA) axis controls cortisol production through the pituitary adrenocorticotropic hormone (ACTH) and feedback mechanisms. The aim of this study was to quantify key mechanisms involved in the HPA axis activity regulation and their interaction with hydrocortisone therapy. Data from 30 healthy volunteers was leveraged: Endogenous ACTH and cortisol concentrations without any intervention as well as cortisol concentrations measured after dexamethasone suppression and single dose administration of (i) 0.5-10 mg hydrocortisone as granules, (ii) 20 mg hydrocortisone as granules and intravenous bolus. A stepwise model development workflow was used: A newly developed model for endogenous ACTH and cortisol was merged with a refined hydrocortisone pharmacokinetic model. The joint model was used to simulate ACTH and cortisol trajectories in CAH patients with varying degrees of enzyme deficiency, with or without hydrocortisone administration, and healthy individuals. Time-dependent ACTH-driven endogenous cortisol production and cortisol-mediated feedback inhibition of ACTH secretion processes were quantified and implemented in the model. Comparison of simulated ACTH and cortisol trajectories between CAH patients and healthy individuals showed the importance of administering hydrocortisone before morning ACTH secretion peak time to suppress ACTH overproduction observed in untreated CAH patients. The developed framework allowed to gain insights on the physiological mechanisms of the HPA axis regulation, its perturbations in CAH and interaction with hydrocortisone administration, paving the way towards cortisol replacement therapy optimization. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ACTH%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ACTH</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Circadian+rhythm%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Circadian rhythm</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Congenital+adrenal+hyperplasia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Congenital adrenal hyperplasia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol+replacement+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol replacement therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Modeling%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Modeling</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fpharmacokinetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/pharmacokinetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adrenocorticotropic+Hormone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adrenocorticotropic Hormone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adrenocorticotropic+Hormone%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adrenocorticotropic Hormone/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hormone+Replacement+Therapy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hormone Replacement Therapy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dexamethasone%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dexamethasone/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dexamethasone%2fpharmacokinetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dexamethasone/pharmacokinetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dexamethasone%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dexamethasone/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Models%2c+Biological%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Models, Biological</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adrenal+Hyperplasia%2c+Congenital%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adrenal Hyperplasia, Congenital/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adrenal+Hyperplasia%2c+Congenital%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adrenal Hyperplasia, Congenital/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adrenal+Hyperplasia%2c+Congenital%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adrenal Hyperplasia, Congenital/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Circadian+Rhythm%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Circadian Rhythm/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Circadian+Rhythm%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Circadian Rhythm/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Healthy+Volunteers%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Healthy Volunteers</a></li></ul> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Freie+Universit%c3%a4t+Berlin+(1008)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Freie Universität Berlin (1008)</a></li></ul> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Park JY</b>, Seok JH, Cho KS, Kang DH, Kim JS, Do SH, Na HS, Jang SA, Ahn RS. Association of salivary testosterone levels during the post-awakening period with age and symptoms suggestive of late-onset hypogonadism in men. <em class='incite-journal-name' onclick='ShowInCiteJournal(2141);'>Ann Med</em> 2024;<b>56</b>:2356667. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38776237' target='_blank'>38776237</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11123501' target='_blank'>PMC11123501</a> DOI: <a href='https://dx.doi.org/10.1080/07853890.2024.2356667' target='_blank'>10.1080/07853890.2024.2356667</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/07853890.2024.2356667','38776237', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(16);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/07853890.2024.2356667' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(2141);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rp.tandfonline.com/submission/login' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 04/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 05/24/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.1080/07853890.2024.2356667" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">The lack of association between serum testosterone levels and symptoms suggestive of hypogonadism is a significant barrier in the determination of late-onset hypogonadism (LOH) in men. This study explored whether testosterone levels increase after morning awakening, likewise the cortisol awakening response (CAR) in the hypothalamic-pituitary-adrenal (HPA) axis, and whether testosterone levels during the post-awakening period are associated with age and symptoms suggestive of late-onset hypogonadism (LOH) in men. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Testosterone and cortisol levels were determined in saliva samples collected immediately upon awakening and 30 and 60 min after awakening, and scores of the Aging Males' Symptoms (AMS) questionnaire were obtained from 225 healthy adult men. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">A typical CAR (an increase in cortisol level ≥ 2.5 nmol/L above individual baseline) was observed in 155 participants (the subgroup exhibiting typical CAR). In the subgroup exhibiting CAR, testosterone levels sharply increased during the post-awakening period, showing a significant negative correlation with age, total AMS score, and the scores of 11 items on the somatic, psychological, and sexual AMS subscales. Of these items, three sexual items (AMS items #15-17) were correlated with age. Meanwhile, there was no notable increase in testosterone levels and no significant correlation of testosterone levels with age and AMS score in the subgroup exhibiting no typical CAR (n = 70). </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">The results indicate that the hypothalamus-pituitary-gonad (HPG) axis responds to morning awakening, and determining testosterone levels during the post-awakening period in men with typical CAR may be useful for assessing HPG axis function and LOH. </div> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ageing+men%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ageing men</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CAR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CAR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22late-onset-hypogonadism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">late-onset-hypogonadism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22post-awakening+period%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">post-awakening period</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22salivary+testosterone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">salivary testosterone</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Testosterone%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Testosterone/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Testosterone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Testosterone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Testosterone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Testosterone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Saliva%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Saliva/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Saliva%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Saliva/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypogonadism%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypogonadism/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypogonadism%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypogonadism/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypogonadism%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypogonadism/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aging%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aging/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aging%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aging/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Surveys+and+Questionnaires%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Surveys and Questionnaires</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Age+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Age Factors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wakefulness%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wakefulness/physiology</a></li></ul> <a href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Azarfarin M</b>, Moradikor N, Matin S, Dadkhah M. Association Between Stress, Neuroinflammation, and Irritable Bowel Syndrome: The Positive Effects of Probiotic Therapy. <em class='incite-journal-name' onclick='ShowInCiteJournal(4590);'>Cell Biochem Funct</em> 2024;<b>42</b>:e70009. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39487668' target='_blank'>39487668</a> DOI: <a href='https://dx.doi.org/10.1002/cbf.70009' target='_blank'>10.1002/cbf.70009</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1002/cbf.70009','39487668', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(17);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(17);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1002/cbf.70009' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4590);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.1002/cbf.70009" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Stress refers to an organism's response to environmental threats in normal condition to maintain homeostasis in the body. In addition, strong inflammatory reactions induced by the hypothalamic-pituitary-adrenal (HPA) axis under stress condition during a long time. Reciprocally, chronic stress can induce the irritable bowel syndrome (IBS) which is a well-known gut disorder thereby play an important role in the promotion and pathophysiology of neuropsychiatric diseases. It has been demonstrated that leaky gut is a hallmark of IBS, leads to the entrance the microbiota into the bloodstream and consequent low-grade systemic inflammation. In the current review, we will discuss the mechanisms by which stress can influence the risk and severity of IBS and its relationship with neuroinflammation. Also, the role of probiotics in IBS co-existing with chronic stress conditions is highlighted. </div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22irritable+bowel+syndrome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">irritable bowel syndrome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22microbiota%e2%80%93gut%e2%80%93brain+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">microbiota–gut–brain axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neuroinflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neuroinflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22probiotic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">probiotic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">stress</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Irritable+Bowel+Syndrome%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Irritable Bowel Syndrome/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Irritable+Bowel+Syndrome%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Irritable Bowel Syndrome/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Probiotics%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Probiotics/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Probiotics%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Probiotics/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroinflammatory+Diseases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroinflammatory Diseases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gastrointestinal+Microbiome%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gastrointestinal Microbiome/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22The+authors+received+no+specific+funding+for+this+work.%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">The authors received no specific funding for this work.</a></li></ul> <a href="javascript:ShowArticleGrant(17);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow18"> <td style="min-width: 40px; text-align: center;"> 18 </td> <td> <div id="citation18" class="article-citation"> <b>Göver T</b>, Slezak M. Targeting glucocorticoid receptor signaling pathway for treatment of stress-related brain disorders. <em class='incite-journal-name' onclick='ShowInCiteJournal(18960);'>Pharmacol Rep</em> 2024;<b>76</b>:1333-1345. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39361217' target='_blank'>39361217</a> DOI: <a href='https://dx.doi.org/10.1007/s43440-024-00654-w' target='_blank'>10.1007/s43440-024-00654-w</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s43440-024-00654-w','39361217', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(18);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(18);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(18);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s43440-024-00654-w' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(18960);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/22/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.1007/s43440-024-00654-w" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The hypothalamic-pituitary-adrenal (HPA) axis plays a central role in governing stress-related disorders such as major depressive disorder (MDD), anxiety, and post-traumatic stress disorder. Chronic stress or early life trauma, known risk factors of disease, alter HPA axis activity and pattern of glucocorticoid (GC) secretion. These changes have consequences for physiological processes controlled by glucocorticoid receptor (GR) signaling, such as immune response and metabolism. In the brain, the aberrant GR signaling translates to altered behavior, making the GR pathway a viable target for therapies of stress-related disorders. One of the crucial elements of the pathway is FKBP5, a regulator of GR sensitivity and feedback control within the HPA axis, in which genetic variants were shown to moderate the risk of developing psychiatric conditions. The difficulty in targeting the GR-FKBP5 pathway stems from tailoring the intervention to specific brain regions and cell types, in the context of personalized genetic variations in GR and GR-associated genes, like FKBP5. The development of selective inhibitors, antagonists, and approaches based on targeted protein degradation offer insights into mechanistic aspects of disease and pave the way for improved therapy. These strategies can be employed either independently or in conjunction with conventional medications. Concomitant advancements in personalized drug screening (e.g. in vitro models exploiting induced pluripotent stem cells, iPSCs) bring the potential for optimization of therapy aiming to rescue central deficits originating from the HPA imbalance. In this mini-review, we discuss potential therapeutic strategies targeting GR signaling in stress-related disorders, with a focus on personalized approaches and advancements in drug development. </div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive-like+behavior%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive-like behavior</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22FKBP51%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">FKBP51</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucocorticoid+receptor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucocorticoid receptor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HPA+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HPA axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Major+depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Major depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22PROTAC%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PROTAC</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress</a></li></ul> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Receptors%2c+Glucocorticoid%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Receptors, Glucocorticoid/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tacrolimus+Binding+Proteins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tacrolimus Binding Proteins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tacrolimus+Binding+Proteins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tacrolimus Binding Proteins/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Diseases%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Diseases/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Diseases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Diseases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; 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Stress, hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-gonadal axis, and aggression. <em class='incite-journal-name' onclick='ShowInCiteJournal(16839);'>Metab Brain Dis</em> 2024;<b>39</b>:1613-1636. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39083184' target='_blank'>39083184</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11535056' target='_blank'>PMC11535056</a> DOI: <a href='https://dx.doi.org/10.1007/s11011-024-01393-w' target='_blank'>10.1007/s11011-024-01393-w</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1007%2fs11011-024-01393-w%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 1</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1007%2fs11011-024-01393-w')">Impact Index Per Article: 1.0</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s11011-024-01393-w','39083184', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(19);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(19);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s11011-024-01393-w' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(16839);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/mebr/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/21/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.1007/s11011-024-01393-w" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">This comprehensive review explores the intricate relationship between the hypothalamic-pituitary-adrenal (HPA) axis, the hypothalamic-pituitary-gonadal (HPG) axis, and aggression. It provides a detailed overview of the physiology and functioning of these axes, as well as the implications for aggressive behavior. The HPA axis, responsible for the stress response, is activated in response to various stressors and can influence aggressive behavior. Glucocorticoids, such as cortisol, play a crucial role in stress-induced activation of the HPA axis and have been implicated in aggressive tendencies. Chronic stress can dysregulate the HPA axis, leading to alterations in cortisol levels and potentially contributing to aggressive behavior. The HPG axis, particularly the androgen hormone testosterone, is also closely linked to aggression. Animal and human studies have consistently shown a positive association between testosterone levels and aggression. The androgen receptors in the brain's neural circuitry play a critical role in modulating aggressive behavior. Interactions between the HPA and HPG axes further contribute to the regulation of aggression. Feedback mechanisms and crosstalk between these axes provide a complex system for the modulation of both stress and reproductive functions, which can impact aggressive behavior. Additionally,the influence of stress on reproductive functions, particularly the role of androgens in stress-induced aggression, adds further complexity to this relationship. The review also discusses the future directions and implications for clinical interventions. Understanding the neurobiological mechanisms underlying aggression requires integrating molecular, cellular, and circuit-level approaches. Translational perspectives, including animal models and human studies, can bridge the gap between basic research and clinical applications. Finally, therapeutic strategies for aggression-related disorders are explored, highlighting the importance of targeted interventions based on a comprehensive understanding of the interactions between the HPA and HPG axes. In conclusion, this review provides a comprehensive overview of the physiological and neurobiological mechanisms underlying aggression, with a specific focus on the interplay between the HPA and HPG axes. By elucidating the complex interactions between stress, hormones, and aggressive behavior, this research paves the way for future investigations and potential therapeutic interventions for aggression-related disorders. </div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aggression-related+disorders%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aggression-related disorders</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Androgen+system%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Androgen system</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucocorticoids%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucocorticoids</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NeurobiologyTestosterone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NeurobiologyTestosterone</a></li></ul> <a href="javascript:ShowArticleKeywords(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aggression%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aggression/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Testosterone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Testosterone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamic-Pituitary-Gonadal+Axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamic-Pituitary-Gonadal Axis</a></li></ul> <a href="javascript:ShowArticleMeSH(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stellenbosch+University%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stellenbosch University</a></li></ul> <a href="javascript:ShowArticleGrant(19);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow20"> <td style="min-width: 40px; text-align: center;"> 20 </td> <td> <div id="citation20" class="article-citation"> <b>Herhaus B</b>, Heni M, Bloch W, Petrowski K. Dynamic interplay of cortisol and BDNF in males under acute and chronic psychosocial stress - A randomized controlled study. <em class='incite-journal-name' onclick='ShowInCiteJournal(19918);'>Psychoneuroendocrinology</em> 2024;<b>170</b>:107192. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39332135' target='_blank'>39332135</a> DOI: <a href='https://dx.doi.org/10.1016/j.psyneuen.2024.107192' target='_blank'>10.1016/j.psyneuen.2024.107192</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psyneuen.2024.107192','39332135', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(20);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(20);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(20);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psyneuen.2024.107192' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19918);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/pnec/default.aspx?pg=mainpage.html' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/16/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/29/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv20" value="10.1016/j.psyneuen.2024.107192" /> <div style="display: none" id="articleAbstract20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The neurotrophic protein brain-derived neurotrophic factor (BDNF) plays a pivotal role in brain function and is affected by acute and chronic stress. We here investigate the patterns of BDNF and cortisol stress reactivity and recovery under the standardized stress protocol of the TSST and the effect of perceived chronic stress on the basal BDNF levels in healthy young men. Twenty-nine lean young men underwent the Trier Social Stress Test (TSST) and a resting condition. Serum BDNF and cortisol were measured before and repeatedly after both conditions. The perception of chronic stress was assessed by the Trier Inventory for Chronic Stress (TICS). After the TSST, there was a significant increase over time for BDNF and cortisol. Stronger increase in cortisol in response to stress was linked to an accelerated BDNF decline after stress. Basal resting levels of BDNF was significantly predicted by chronic stress perception. The increased BDNF level following psychosocial stress suggest a stress-induced neuroprotective mechanism. The presumed interplay between BDNF and the HPA-axis indicates an antagonistic relationship of cortisol on BDNF recovery post-stress. Chronically elevated high cortisol levels, as present in chronic stress, could thereby contribute to reduced neurogenesis, and an increased risk of neurodegenerative conditions in persons suffering from chronic stress. </div> <a href="javascript:ShowArticleAbstract(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+derived+neurotrophic+factor+(BDNF)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain derived neurotrophic factor (BDNF)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamic-pituitary-adrenocortical+(HPA)+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamic-pituitary-adrenocortical (HPA) axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Trier+Social+Stress+Test+(TSST)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Trier Social Stress Test (TSST)</a></li></ul> <a href="javascript:ShowArticleKeywords(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-Derived+Neurotrophic+Factor%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-Derived Neurotrophic Factor/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+Disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic Disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+Disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute Disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Saliva%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Saliva/chemistry</a></li></ul> <a href="javascript:ShowArticleMeSH(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(20);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow21"> <td style="min-width: 40px; text-align: center;"> 21 </td> <td> <div id="citation21" class="article-citation"> <b>Duffy KA</b>, Sammel MD, Johnson RL, Morrison KE, Bale TL, Epperson CN. Sex Differences in Stress-Induced Cortisol Response Among Infants of Mothers Exposed to Childhood Adversity. <em class='incite-journal-name' onclick='ShowInCiteJournal(3582);'>Biol Psychiatry</em> 2024;<b>96</b>:876-885. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38821195' target='_blank'>38821195</a> DOI: <a href='https://dx.doi.org/10.1016/j.biopsych.2024.05.015' target='_blank'>10.1016/j.biopsych.2024.05.015</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biopsych.2024.05.015','38821195', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(21);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(21);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(21);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biopsych.2024.05.015' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3582);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/bps/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/08/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 05/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 05/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 06/02/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv21" value="10.1016/j.biopsych.2024.05.015" /> <div style="display: none" id="articleAbstract21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Adverse childhood experiences (ACEs) increase risk for mental illness in women and their children, and dysregulation of the hypothalamic-pituitary-adrenal axis may play a role. The impact of ACEs on the hypothalamic-pituitary-adrenal axis may be strongest when ACEs occur prepubertally and in people who are exposed to abuse ACEs. </div><div class="abstract-label">METHODS</div><div class="abstract-content">To test this, we measured salivary cortisol in 96 mother-infant dyads while mothers were separated from their infants, who were experiencing a laboratory stressor. Mothers completed the Adverse Childhood Experiences Questionnaire; ACEs that occurred prepubertally (pACEs) were measured, and mother-infant dyads were grouped based on maternal pACE history as follows: no pACEs, ≥1 pACEs with abuse, or ≥1 pACEs but no abuse. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Mothers with ≥1 pACEs exhibited decreases in cortisol (relative to preinfant stressor), which differed significantly from the cortisol increase experienced by mothers with no pACEs, regardless of abuse presence (p = .001) or absence (p = .002). These pACE groups did not differ from one another (p = .929). Significant sex differences in infant cortisol were observed in infants of mothers with ≥1 pACEs (regardless of abuse) but not in infants of mothers with no pACEs. When mothers had experienced ≥1 pACEs, males showed decreases in cortisol in response to a stressor whereas females demonstrated increases, and males and females differed significantly when their mothers had ≥1 pACEs with (p = .025) and without (p = .032) abuse. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">Regardless of maternal exposure to childhood abuse, in response to a stressor, pACEs were associated with lower cortisol response in mothers and sex differences in 6-month-old infants, with males showing a lower cortisol response than females. </div> <a href="javascript:ShowArticleAbstract(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adverse+childhood+experiences%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adverse childhood experiences</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cortisol+reactivity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cortisol reactivity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Early-life+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Early-life stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intergenerational+transmission+of+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intergenerational transmission of stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex+differences%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex differences</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress+physiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress physiology</a></li></ul> <a href="javascript:ShowArticleKeywords(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adverse+Childhood+Experiences%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adverse Childhood Experiences</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Saliva%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Saliva/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Saliva%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Saliva/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mothers%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mothers/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex+Characteristics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex Characteristics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mother-Child+Relations%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mother-Child Relations/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex Factors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li></ul> <a href="javascript:ShowArticleMeSH(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(21);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow22"> <td style="min-width: 40px; text-align: center;"> 22 </td> <td> <div id="citation22" class="article-citation"> <b>Das A</b>, Suar M, Reddy KS. Hormones in malaria infection: influence on disease severity, host physiology, and therapeutic opportunities. <em class='incite-journal-name' onclick='ShowInCiteJournal(3705);'>Biosci Rep</em> 2024;<b>44</b>:BSR20240482. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39492784' target='_blank'>39492784</a> DOI: <a href='https://dx.doi.org/10.1042/bsr20240482' target='_blank'>10.1042/bsr20240482</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1042/bsr20240482','39492784', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(22);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(22);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(22);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(22);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1042/bsr20240482' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3705);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 11/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv22" value="10.1042/bsr20240482" /> <div style="display: none" id="articleAbstract22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Human malaria, caused by Plasmodium parasites, is a fatal disease that disrupts the host's physiological balance and affects the neuroendocrine system. This review explores how malaria influences and is influenced by hormones. Malaria activates the Hypothalamus-Pituitary-Adrenal axis, leading to increased cortisol, aldosterone, and epinephrine. Cortisol, while reducing inflammation, aids parasite survival, whereas epinephrine helps manage hypoglycemia. The Hypothalamus-Pituitary-Gonad and Hypothalamus-Pituitary-Thyroid axes are also impacted, resulting in lower sex and thyroid hormone levels. Malaria disrupts the renin-angiotensin-aldosterone system (RAAS), causing higher angiotensin-II and aldosterone levels, contributing to edema, hyponatremia and hypertension. Malaria-induced anemia is exacerbated by increased hepcidin, which impairs iron absorption, reducing both iron availability for the parasite and red blood cell formation, despite elevated erythropoietin. Hypoglycemia is common due to decreased glucose production and hyperinsulinemia, although some cases show hyperglycemia due to stress hormones and inflammation. Hypocalcemia, and hypophosphatemia are associated with low Vitamin D3 and parathyroid hormone but high calcitonin. Hormones such as DHEA, melatonin, PTH, Vitamin D3, hepcidin, progesterone, and erythropoietin protects against malaria. Furthermore, synthetic analogs, receptor agonists and antagonists or mimics of hormones like DHEA, melatonin, serotonin, PTH, vitamin D3, estrogen, progesterone, angiotensin, and somatostatin are being explored as potential antimalarial treatments or adjunct therapies. Additionally, hormones like leptin and PCT are being studied as probable markers of malaria infection. </div> <a href="javascript:ShowArticleAbstract(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Human+hormones%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Human hormones</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plasmodium%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plasmodium</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22antimalarial%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">antimalarial</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22host-pathogen+interactions%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">host-pathogen interactions</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22malaria%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">malaria</a></li></ul> <a href="javascript:ShowArticleKeywords(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Malaria%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Malaria/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Malaria%2fparasitology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Malaria/parasitology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Malaria%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Malaria/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hormones%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hormones/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Renin-Angiotensin+System%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Renin-Angiotensin System/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plasmodium%2fpathogenicity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plasmodium/pathogenicity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plasmodium%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plasmodium/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Department+of+Science+and+Technology%2c+Ministry+of+Science+and+Technology%2c+India+(DST)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DST/SERB/CRG/2021/004718 Department of Science and Technology, Ministry of Science and Technology, India (DST)</a></li></ul> <a href="javascript:ShowArticleGrant(22);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow23"> <td style="min-width: 40px; text-align: center;"> 23 </td> <td> <div id="citation23" class="article-citation"> <b>Janson-Schmitt J</b>, Rohleder N. Interventions to modify the habituation of biological responses to repeated stress in healthy adults: a randomized controlled trial. <em class='incite-journal-name' onclick='ShowInCiteJournal(23021);'>Trials</em> 2024;<b>25</b>:783. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39563430' target='_blank'>39563430</a> DOI: <a href='https://dx.doi.org/10.1186/s13063-024-08620-w' target='_blank'>10.1186/s13063-024-08620-w</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1186/s13063-024-08620-w','39563430', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(23);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(23);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(23);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1186/s13063-024-08620-w' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(23021);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/21/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv23" value="10.1186/s13063-024-08620-w" /> <div style="display: none" id="articleAbstract23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Changes in response patterns of biological stress systems, including responses of the sympathetic nervous system (SNS) and the hypothalamus-pituitary-adrenal (HPA) axis to repeated stress, can promote the development and progression of chronic diseases via changes in downstream inflammatory processes. The aim of this project is thus to investigate, whether habituation of biological stress system activity including responses of the inflammatory system can be modified. Aiming to test for possible paths of action, a randomized controlled study with two intervention programs designed to manipulate cognitive coping strategies will be carried out. By increasing either ruminative or self-compassionate thoughts among healthy young adults, the intervention programs are expected to affect the regulation of occurring emotions as expressed by the responsiveness of biological systems during repeated stress exposure. </div><div class="abstract-label">METHODS</div><div class="abstract-content">In this study, a total of 120 healthy adults will complete the Trier Social Stress Test (TSST) on two consecutive days. Immediately after the first stress induction, participants will be randomly assigned to two experimental conditions designed to manipulate cognitive coping strategies (rumination vs. self-compassion) or a control condition. Measures of HPA axis (salivary cortisol) and autonomic activity (salivary alpha amylase, heart rate, heart rate variability) as well as inflammatory markers (plasma interleukin(IL)-6, expression rates of pro- and anti-inflammatory cytokine genes) will be repeatedly assessed throughout the experimental sessions. Response and habituation indices of these measures will be calculated and compared between the experimental conditions and the control condition. </div><div class="abstract-label">DISCUSSION</div><div class="abstract-content">The results should provide insight into whether modifying response patterns of biological stress systems could reverse a significant biological mechanism in the development of stress-related diseases. </div><div class="abstract-label">TRIAL REGISTRATION</div><div class="abstract-content">German Clinical Trials Register (DKRS), DRKS00034790. Registered on August 12, 2024, https://www.drks.de/DRKS00034790 . </div> <a href="javascript:ShowArticleAbstract(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Allostatic+load%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Allostatic load</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+expression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene expression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Habituation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Habituation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Repeated+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Repeated stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rumination%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rumination</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Self-compassion%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Self-compassion</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress+response+patterns%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress response patterns</a></li></ul> <a href="javascript:ShowArticleKeywords(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothalamo-Hypophyseal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothalamo-Hypophyseal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Habituation%2c+Psychophysiologic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Habituation, Psychophysiologic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adaptation%2c+Psychological%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adaptation, Psychological</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrocortisone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrocortisone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Randomized+Controlled+Trials+as+Topic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Randomized Controlled Trials as Topic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Healthy+Volunteers%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Healthy Volunteers</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heart+Rate%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heart Rate</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adolescent%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adolescent</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Saliva%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Saliva/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(23);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow24"> <td style="min-width: 40px; text-align: center;"> 24 </td> <td> <div id="citation24" class="article-citation"> <b>Tian S</b>, Liu M, Yang C, Du W, Gao B, Li M, Pan T, Liu T, Song Q, Lin L, Zhang H, Miao Y. The impact of ACTH levels on neurotransmitters and antioxidants in patients with major depressive disorder: A novel investigation. <em class='incite-journal-name' onclick='ShowInCiteJournal(13076);'>J Affect Disord</em> 2024;<b>365</b>:587-596. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39191311' target='_blank'>39191311</a> DOI: <a href='https://dx.doi.org/10.1016/j.jad.2024.08.142' target='_blank'>10.1016/j.jad.2024.08.142</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jad.2024.08.142','39191311', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(24);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(24);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(24);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jad.2024.08.142' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13076);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/jafd/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/29/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv24" value="10.1016/j.jad.2024.08.142" /> <div style="display: none" id="articleAbstract24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">The relationship between neurotransmitters and oxidative stress in Major Depressive Disorder (MDD) patients, considering HPA axis activity and psychological and cognitive states, is unclear. This study examines changes in neurotransmitters (GABA, Glx) and antioxidants (GSH) in the dorsal anterior cingulate cortex (dACC) of MDD patients under varying levels of ACTH, and their relationship with psychological and cognitive conditions. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Forty-five MDD patients were divided into high-ACTH (>65 pg/mL; n = 16) and normal-ACTH (7-65 pg/mL; n = 29) groups based on blood ACTH levels, along with 12 healthy controls (HC). All participants underwent HAM-D, HAM-A assessments, and most completed MMSE and MoCA tests. GABA+, Glx, and GSH levels in the dACC were measured using the MEGA-PRESS sequence. Intergroup differences and correlations between clinical factors, HPA axis activity, and metabolites were analyzed. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Compared to HC, the normal ACTH group showed higher Glx and lower GSH levels. Glx and GSH were negatively correlated with MDD severity. In the high-ACTH MDD group, Glx positively correlated with delayed memory, and GSH positively correlated with abstraction. Factors influencing GABA included ACTH levels, depression duration, and negative events. Predictive factors for HAM-D scores were GSH and GABA. </div><div class="abstract-label">LIMITATIONS</div><div class="abstract-content">The sample size is small. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">MDD patients exhibit neurochemical differences in the brain related to HPA axis levels, MDD severity, and cognitive function. Clinical factors, neurotransmitters, and neuroendocrine levels significantly influence depression severity. </div> <a href="javascript:ShowArticleAbstract(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ACTH%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ACTH</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22GABA%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">GABA</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22GSH%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">GSH</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glx%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glx</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HPA+axis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HPA axis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Major+depressive+disorder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Major depressive disorder</a></li></ul> <a href="javascript:ShowArticleKeywords(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Major%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Major/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Major%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Major/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Major%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Major/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adrenocorticotropic+Hormone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adrenocorticotropic Hormone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a 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target="_blank">Pituitary-Adrenal System/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pituitary-Adrenal+System%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pituitary-Adrenal System/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxidative+Stress%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxidative Stress/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Case-Control+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Case-Control Studies</a></li></ul> <a href="javascript:ShowArticleMeSH(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(24);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow25"> <td style="min-width: 40px; text-align: center;"> 25 </td> <td> <div id="citation25" class="article-citation"> <b>Porras A</b>, Rodney-Hernández P, Jackson J, Nguyen CH, Rincón-Cortés M. Sex-dependent effects of early life sensory overstimulation on later life behavioral function in rats. <em class='incite-journal-name' onclick='ShowInCiteJournal(20954);'>Sci Rep</em> 2024;<b>14</b>:27650. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39532944' target='_blank'>39532944</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557974' target='_blank'>PMC11557974</a> DOI: <a href='https://dx.doi.org/10.1038/s41598-024-78928-9' target='_blank'>10.1038/s41598-024-78928-9</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1038/s41598-024-78928-9','39532944', 'Pituitary-Adrenal System/metabolism')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(25);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(25);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(25);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1038/s41598-024-78928-9' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20954);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/16/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv25" value="10.1038/s41598-024-78928-9" /> <div style="display: none" id="articleAbstract25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Children today are immersed in electronic technology shortly after birth as they now begin regularly watching television earlier than they did in the past. Many new programs geared towards infants contain lots of lights, color, and sounds, which may constitute a form of sensory overstimulation (SOS) that leads to cognitive and behavioral changes in children and adolescents. Here, we examined the impact of early life SOS exposure on later life behavioral and cognitive function in rodents by exposing developing male and female rats to excessive audiovisual stimulation from postnatal days (PND) 10-40 and assessing anxiety-like behavior, social motivation, compulsive behavior, and spatial learning/cognition from PND 50-60. To evaluate potential SOS effects on hypothalamic-pituitary-adrenal (HPA)-axis function, levels of the stress hormone corticosterone (CORT) were measured at 3 timepoints (e.g., PND 23, 41, 61) post-SOS exposure. Sensory overstimulated males exhibited reduced anxiety-like and compulsive behavior compared to controls, whereas females exhibited reduced social motivation but enhanced spatial learning/cognition compared to controls. No differences in baseline CORT levels were found at any age tested, suggesting no impact of early life SOS on later life basal HPA-axis function. Our results demonstrate sex-specific effects of early life SOS on distinct behavioral domains in early adult rats. </div> <a href="javascript:ShowArticleAbstract(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22learning+and+memory%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">learning and memory</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22motivation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">motivation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22reward%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" 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Influence Index</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle2">Article Influence Index</span></b> </p> <p> Total Citations in Crossref ÷ Total Articles = <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">Pituitary-Adrenal System/metabolism (2603 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_1169734383" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">Pituitary-Adrenal System/metabolism (2603 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" 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All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>