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</li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Reference</span> </div> </a> <ul id="toc-Reference-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Spoljašnje_veze" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Spoljašnje_veze"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Spoljašnje veze</span> </div> </a> <ul id="toc-Spoljašnje_veze-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sadržaj" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Prikaži/sakrij sadržaj" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Prikaži/sakrij sadržaj</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading" lang="sh-Latn" dir="ltr"><span class="mw-page-title-main">Interleukin 35</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Prijedi na druge jezične varijante članka. Dostupno je na 5 jezika" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-5" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">5 jezika</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Interleukin_35" title="Interleukin 35 — Češki" lang="cs" hreflang="cs" data-title="Interleukin 35" data-language-autonym="Čeština" data-language-local-name="Češki" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Interleukin_35" title="Interleukin 35 — Engleski" lang="en" hreflang="en" data-title="Interleukin 35" data-language-autonym="English" data-language-local-name="Engleski" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Interleuchina_35" title="Interleuchina 35 — Italijanski" lang="it" hreflang="it" data-title="Interleuchina 35" data-language-autonym="Italiano" data-language-local-name="Italijanski" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Interleukina_35" title="Interleukina 35 — Poljski" lang="pl" hreflang="pl" data-title="Interleukina 35" data-language-autonym="Polski" data-language-local-name="Poljski" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_35" title="Интерлеукин 35 — Srpski" lang="sr" hreflang="sr" data-title="Интерлеукин 35" data-language-autonym="Српски / srpski" data-language-local-name="Srpski" class="interlanguage-link-target"><span>Српски / srpski</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q6047058#sitelinks-wikipedia" title="Uredi međujezične poveznice" class="wbc-editpage">Uredi veze</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Imenski prostori"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" lang="sh-Latn" dir="ltr"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Interleukin_35" title="Vidi stranicu sadržaja [c]" accesskey="c"><span>Stranica</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Razgovor:Interleukin_35" rel="discussion" title="Razgovarajte o sadržini ove stranice [t]" accesskey="t"><span>Razgovor</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown " lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Promijeni jezičnu varijantu" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Latinica</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants" lang="sh-Latn" dir="ltr"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-varlang-0" class="selected ca-variants-sh-Latn mw-list-item"><a href="/w/index.php?title=Interleukin_35&variant=sh-latn" lang="sh-Latn" hreflang="sh-Latn"><span>Latinica</span></a></li><li id="ca-varlang-1" class="ca-variants-sh-Cyrl mw-list-item"><a href="/w/index.php?title=Interleukin_35&variant=sh-cyrl" lang="sh-Cyrl" hreflang="sh-Cyrl"><span>Ћирилица</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Teme"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" lang="sh-Latn" dir="ltr"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Interleukin_35"><span>Prikaži</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Interleukin_35&veaction=edit" title="Uredite ovu stranicu [v]" accesskey="v"><span>Uredi</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Interleukin_35&action=edit" title="Uredite izvorni kod ove stranice [e]" accesskey="e"><span>Uredi kod</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Interleukin_35&action=history" title="Pogledajte prethodne verzije ove stranice [h]" accesskey="h"><span>Historija</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Pomagala"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Alatke" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Alatke</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Alati</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">sakrij</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Više mogućnosti" lang="sh-Latn" dir="ltr"> <div class="vector-menu-heading"> Radnje </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Interleukin_35"><span>Prikaži</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Interleukin_35&veaction=edit" title="Uredite ovu stranicu [v]" accesskey="v"><span>Uredi</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Interleukin_35&action=edit" title="Uredite izvorni kod ove stranice [e]" accesskey="e"><span>Uredi kod</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Interleukin_35&action=history"><span>Historija</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" lang="sh-Latn" dir="ltr"> <div class="vector-menu-heading"> Opšte </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Posebno:%C5%A0to_vodi_ovdje/Interleukin_35" title="Pogledajte listu svih stranica koje vode ovamo [j]" accesskey="j"><span>Šta vodi ovamo</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Posebno:Povezane_izmjene/Interleukin_35" rel="nofollow" title="Prelistajte nedavne izmjene stranica koje su povezane s ovom [k]" accesskey="k"><span>Povezane izmjene</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Posebno:Posebne_stranice" title="Pregledajte listu svih posebnih stranica [q]" accesskey="q"><span>Posebne stranice</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Interleukin_35&oldid=4605863" title="Nabavite trajnu vezu do ove verzije stranice"><span>Trajna veza</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Interleukin_35&action=info" title="Pronađite više informacija o ovoj stranici"><span>Podaci o stranici</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Posebno:Citiraj&page=Interleukin_35&id=4605863&wpFormIdentifier=titleform" title="Saznajte kako da citirate ovu stranicu"><span>Citiraj stranicu</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Posebno:Skra%C4%87iva%C4%8D_adresa&url=https%3A%2F%2Fsh.wikipedia.org%2Fwiki%2FInterleukin_35"><span>Skrati URL</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Posebno:QrCode&url=https%3A%2F%2Fsh.wikipedia.org%2Fwiki%2FInterleukin_35"><span>Preuzmi QR kod</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" lang="sh-Latn" dir="ltr"> <div class="vector-menu-heading"> Štampanje/izvoz </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Posebno:Kolekcija&bookcmd=book_creator&referer=Interleukin+35"><span>Napravi knjigu</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Posebno:DownloadAsPdf&page=Interleukin_35&action=show-download-screen"><span>Preuzmi kao PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Interleukin_35&printable=yes" title="Odštampajte ovu stranicu [p]" accesskey="p"><span>Odštampaj</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" lang="sh-Latn" dir="ltr"> <div class="vector-menu-heading"> Na drugim projektima </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q6047058" title="Pogledajte povezanu stavku u skladištu podataka [g]" accesskey="g"><span>Stavka na Wikipodacima</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Pomagala"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Izgled"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Izgled</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">sakrij</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Izvor: Wikipedija</div> </div> <div id="contentSub" lang="sh-Latn" dir="ltr"><div id="mw-content-subtitle" lang="sh-Latn" dir="ltr"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sh-Latn" dir="ltr"><p><b>Interleukin 35</b> (IL-35) pripada <a href="/wiki/Interleukin_12" title="Interleukin 12">IL-12</a> familiji citokina koju proizvode <a href="/w/index.php?title=Regulatornu_T_%C4%87elije&action=edit&redlink=1" class="new" title="Regulatornu T ćelije (stranica ne postoji)">regulatorne</a>, ali ne efektorske, <a href="/w/index.php?title=T_%C4%87elija&action=edit&redlink=1" class="new" title="T ćelija (stranica ne postoji)">T ćelije</a> i koja igra ulogu u <a href="/wiki/Imunosupresija" title="Imunosupresija">imunosupresiji</a>. To je dimerični <a href="/wiki/Protein" title="Protein">protein</a> koji se sastoji od <a href="/wiki/Interleukin_12" title="Interleukin 12">IL-12α</a> i <a href="/wiki/Interleukin_27" title="Interleukin 27">IL-27β</a> lanaca, koji su kodirani sa dva posebna <a href="/wiki/Gen" title="Gen">gena</a> zvana <i><a href="/w/index.php?title=IL12A&action=edit&redlink=1" class="new" title="IL12A (stranica ne postoji)">IL12A</a></i> i <i><a href="/w/index.php?title=EBI3&action=edit&redlink=1" class="new" title="EBI3 (stranica ne postoji)">EBI3</a></i>, respektivno. Nakon što je izlučen iz regulatornih T ćelija (T<sub>reg</sub>), IL-35 supresira <a href="/wiki/Inflamacija" class="mw-disambig" title="Inflamacija">inflamatorni odgovor</a> imunih ćelija. Studije na miševima su pokazale da odsustvo bilo kojeg IL-35 lanca iz regulatornih T<sub>geg</sub> redukuje ćelijsku sposobnost da supresuju inflamaciju<sup id="cite_ref-KubyImmunology6th_1-0" class="reference"><a href="#cite_note-KubyImmunology6th-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>; to je zapaženo u toku eksperimenata na <a href="/w/index.php?title=%C4%86elijskim_kulturama&action=edit&redlink=1" class="new" title="Ćelijskim kulturama (stranica ne postoji)">ćelijskim kulturama</a> i koristeći eksperimentalni model za <a href="/w/index.php?title=Upalna_bolest_creva&action=edit&redlink=1" class="new" title="Upalna bolest creva (stranica ne postoji)">upalnu bolest creva</a>.<sup id="cite_ref-pmid18033300_2-0" class="reference"><a href="#cite_note-pmid18033300-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Da bi proizveo svoje supresivne efekte, IL-35 ima selektivne aktivnosti na različitim podskupovima T ćelija; on inducira <a href="/wiki/%C4%86elijski_rast" title="Ćelijski rast">proliferaciju</a> T<sub>reg</sub> ćelijskih populacija ali umanjuje aktivnost <a href="/wiki/T_pomo%C4%87ne_17_%C4%87elije" title="T pomoćne 17 ćelije">T<sub>h</sub>17 ćelijskih</a> populacija.<sup id="cite_ref-pmid17874423_3-0" class="reference"><a href="#cite_note-pmid17874423-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_35&veaction=edit&section=1" title="Uredi odjeljak Reference" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_35&action=edit&section=1" title="Uredi kôd odjeljka Reference"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r41556849">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-KubyImmunology6th-1"><span class="mw-cite-backlink"><a href="#cite_ref-KubyImmunology6th_1-0">↑</a></span> <span class="reference-text"><span class="citation book">Thomas J. Kindt, Richard A. Goldsby, Barbara Anne Osborne, Janis Kuby (2006). <a rel="nofollow" class="external text" href="http://bcs.whfreeman.com/immunology6e/default.asp?s=&n=&i=&v=&o=&ns=0&uid=0&rau=0"><i>Kuby Immunology</i></a> (6 izd.). New York: W H Freeman and company. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Posebno:Tra%C5%BEi_ISBN/1-4292-0211-4" title="Posebno:Traži ISBN/1-4292-0211-4">1-4292-0211-4</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Kuby+Immunology&rft.aulast=Thomas+J.+Kindt%2C+Richard+A.+Goldsby%2C+Barbara+Anne+Osborne%2C+Janis+Kuby&rft.au=Thomas+J.+Kindt%2C+Richard+A.+Goldsby%2C+Barbara+Anne+Osborne%2C+Janis+Kuby&rft.date=2006&rft.edition=6&rft.place=New+York&rft.pub=W+H+Freeman+and+company&rft.isbn=1-4292-0211-4&rft_id=http%3A%2F%2Fbcs.whfreeman.com%2Fimmunology6e%2Fdefault.asp%3Fs%3D%26n%3D%26i%3D%26v%3D%26o%3D%26ns%3D0%26uid%3D0%26rau%3D0&rfr_id=info:sid/en.wikipedia.org:Interleukin_35"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid18033300-2"><span class="mw-cite-backlink"><a href="#cite_ref-pmid18033300_2-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Collison LW, Workman CJ, Kuo TT, <i>et al.</i> (November 2007). „The inhibitory cytokine IL-35 contributes to regulatory T-cell function”. <i>Nature</i> <b>450</b> (7169): 566–9. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnature06306">10.1038/nature06306</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18033300">18033300</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+inhibitory+cytokine+IL-35+contributes+to+regulatory+T-cell+function&rft.jtitle=Nature&rft.aulast=Collison+LW%2C+Workman+CJ%2C+Kuo+TT%2C+%27%27et+al.%27%27&rft.au=Collison+LW%2C+Workman+CJ%2C+Kuo+TT%2C+%27%27et+al.%27%27&rft.date=November+2007&rft.volume=450&rft.issue=7169&rft.pages=566%E2%80%939&rft_id=info:doi/10.1038%2Fnature06306&rft_id=info:pmid/18033300&rfr_id=info:sid/en.wikipedia.org:Interleukin_35"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid17874423-3"><span class="mw-cite-backlink"><a href="#cite_ref-pmid17874423_3-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Niedbala W, Wei XQ, Cai B, <i>et al.</i> (November 2007). „IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells”. <i>Eur. J. Immunol.</i> <b>37</b> (11): 3021–9. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002%2Feji.200737810">10.1002/eji.200737810</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17874423">17874423</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=IL-35+is+a+novel+cytokine+with+therapeutic+effects+against+collagen-induced+arthritis+through+the+expansion+of+regulatory+T+cells+and+suppression+of+Th17+cells&rft.jtitle=Eur.+J.+Immunol.&rft.aulast=Niedbala+W%2C+Wei+XQ%2C+Cai+B%2C+%27%27et+al.%27%27&rft.au=Niedbala+W%2C+Wei+XQ%2C+Cai+B%2C+%27%27et+al.%27%27&rft.date=November+2007&rft.volume=37&rft.issue=11&rft.pages=3021%E2%80%939&rft_id=info:doi/10.1002%2Feji.200737810&rft_id=info:pmid/17874423&rfr_id=info:sid/en.wikipedia.org:Interleukin_35"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text"><span class="citation book">Mire-Sluis, Anthony R.; Thorpe, Robin, ur. (1998). <a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/book/9780124983403"><i>Cytokines (Handbook of Immunopharmacology)</i></a>. Boston: Academic Press. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Posebno:Tra%C5%BEi_ISBN/0-12-498340-5" title="Posebno:Traži ISBN/0-12-498340-5">0-12-498340-5</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Cytokines+%28Handbook+of+Immunopharmacology%29&rft.date=1998&rft.place=Boston&rft.pub=Academic+Press&rft.isbn=0-12-498340-5&rft_id=http%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbook%2F9780124983403&rfr_id=info:sid/en.wikipedia.org:Interleukin_35"><span style="display: none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Spoljašnje_veze"><span id="Spolja.C5.A1nje_veze"></span>Spoljašnje veze</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_35&veaction=edit&section=2" title="Uredi odjeljak Spoljašnje veze" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_35&action=edit&section=2" title="Uredi kôd odjeljka Spoljašnje veze"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Medical_Subject_Headings" class="mw-redirect" title="Medical Subject Headings">MeSH</a> <i><a rel="nofollow" class="external text" href="//www.nlm.nih.gov/cgi/mesh/2009/MB_cgi?mode=&term=Interleukin-35">Interleukin-35</a></i></li> <li class="mw-empty-elt"></li> <li><span typeof="mw:File"><a href="https://commons.wikimedia.org/wiki/Cytokines" title="Cytokines"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/12px-Commons-logo.svg.png" decoding="async" width="12" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/18px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/24px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span> <a href="https://commons.wikimedia.org/wiki/Main_page" class="extiw" title="commons:Main page">Wikimedia Commons</a> ima još multimedijalnih datoteka vezanih za: <b><i><a href="https://commons.wikimedia.org/wiki/Category:Cytokines" class="extiw" title="commons:Category:Cytokines">Interleukin 35</a></i></b></li></ul> <div style="clear:both;"></div> <div class="navbox-styles nomobile"><style data-mw-deduplicate="TemplateStyles:r41348688">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output 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10">IL-10</a> •  <a href="/wiki/Interleukin_11" title="Interleukin 11">IL-11</a> •  <a href="/wiki/Interleukin_12" title="Interleukin 12">IL-12</a> (<a href="/wiki/Interleukin_12B" title="Interleukin 12B">B</a>) •  <a href="/wiki/Interleukin_13" title="Interleukin 13">IL-13</a> •  <a href="/wiki/Interleukin_14" title="Interleukin 14">IL-14</a> •  <a href="/wiki/Interleukin_15" title="Interleukin 15">IL-15</a> •  <a href="/wiki/Interleukin_16" title="Interleukin 16">IL-16</a> •  <a href="/wiki/Interleukin_17" title="Interleukin 17">IL-17</a> (<a href="/wiki/Interleukin_17A" title="Interleukin 17A">A</a>) •  <a href="/wiki/Interleukin_18" title="Interleukin 18">IL-18</a> •  <a href="/wiki/Interleukin_19" title="Interleukin 19">IL-19</a> •  <a href="/wiki/Interleukin_20" title="Interleukin 20">IL-20</a> •  <a href="/wiki/Interleukin_21" title="Interleukin 21">IL-21</a> •  <a href="/wiki/Interleukin_22" title="Interleukin 22">IL-22</a> •  <a href="/wiki/Interleukin_23" title="Interleukin 23">IL-23</a> •  <a href="/wiki/Interleukin_24" title="Interleukin 24">IL-24</a> •  <a href="/wiki/Interleukin_25" title="Interleukin 25">IL-25</a> •  <a href="/wiki/Interleukin_26" title="Interleukin 26">IL-26</a> •  <a href="/wiki/Interleukin_27" title="Interleukin 27">IL-27</a> •  <a href="/wiki/Interleukin_28" title="Interleukin 28">IL-28</a> •  <a href="/wiki/Interleukin_29" title="Interleukin 29">IL-29</a> •  <a href="/wiki/Interleukin_30" title="Interleukin 30">IL-30</a> •  <a href="/wiki/Interleukin_31" title="Interleukin 31">IL-31</a> •  <a href="/wiki/Interleukin_32" title="Interleukin 32">IL-32</a> •  <a href="/wiki/Interleukin_33" title="Interleukin 33">IL-33</a> •  <a href="/wiki/Interleukin_34" title="Interleukin 34">IL-34</a> •  <a class="mw-selflink selflink">IL-35</a></div></td></tr></tbody></table></div> <div class="navbox-styles nomobile"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41348688"></div><div role="navigation" class="navbox" aria-labelledby="Ćelijska_komunikacija:_Citokini" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41556979"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41556873"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-prikaži"><a href="/wiki/%C5%A0ablon:Citokini-lat" title="Šablon:Citokini-lat"><abbr title="Pogledajte šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">p</abbr></a></li><li class="nv-razgovor"><a href="/wiki/Razgovor_o_%C5%A1ablonu:Citokini-lat" title="Razgovor o šablonu:Citokini-lat"><abbr title="Razgovarajte o šablonu" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">r</abbr></a></li><li class="nv-uredi"><a class="external text" href="https://sh.wikipedia.org/w/index.php?title=%C5%A0ablon:Citokini-lat&action=edit"><abbr title="Uredite šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">u</abbr></a></li></ul></div><div id="Ćelijska_komunikacija:_Citokini" style="font-size:114%;margin:0 4em"><a href="/wiki/%C4%86elijska_komunikacija" title="Ćelijska komunikacija">Ćelijska komunikacija</a>: <a href="/wiki/Citokini" class="mw-redirect" title="Citokini">Citokini</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Po familiji</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interleukin" title="Interleukin">Interleukin</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-1" class="mw-disambig" title="IL-1">IL-1</a> superfamilija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_1" title="Interleukin 1">1</a> (<a href="/wiki/Antagonist_interleukin-1_receptora" title="Antagonist interleukin-1 receptora">1Ra</a>) •  <a href="/wiki/Interleukin_18" title="Interleukin 18">18</a> •  <a href="/wiki/Interleukin_33" title="Interleukin 33">33</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">poput <a href="/wiki/IL-6" class="mw-disambig" title="IL-6">IL-6</a>/<a href="/wiki/Glikoprotein_130" title="Glikoprotein 130">gp130</a> koristeći</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_6" title="Interleukin 6">6</a>  •  <a href="/wiki/Interleukin_11" title="Interleukin 11">11</a> •  <a href="/wiki/Interleukin_27" title="Interleukin 27">27</a> •  <a href="/wiki/Interleukin_30" title="Interleukin 30">30</a> •  <a href="/wiki/Interleukin_31" title="Interleukin 31">31</a> (+ne IL <a href="/wiki/Onkostatin_M" title="Onkostatin M">Onkostatin M</a>, <a href="/wiki/Inhibitorni_faktor_leukemije" title="Inhibitorni faktor leukemije">Inhibitorni faktor leukemije</a>, <a href="/wiki/Cilijarni_neurotrofni_faktor" title="Cilijarni neurotrofni faktor">Cilijarni neurotrofni faktor</a>, <a href="/wiki/Kardiotrofin_1" title="Kardiotrofin 1">Kardiotrofin 1</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-10" class="mw-disambig" title="IL-10">IL-10</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_10" title="Interleukin 10">10</a> •  <a href="/wiki/Interleukin_19" title="Interleukin 19">19</a> •  <a href="/wiki/Interleukin_20" title="Interleukin 20">20</a> •  <a href="/wiki/Interleukin_22" title="Interleukin 22">22</a> •  <a href="/wiki/Interleukin_24" title="Interleukin 24">24</a> •  <a href="/wiki/Interleukin_26" title="Interleukin 26">26</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">Interferon tip III</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_28" title="Interleukin 28">28</a> •  <a href="/wiki/Interleukin_29" title="Interleukin 29">29</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Zajedni%C4%8Dki_gama_lanac" class="mw-redirect" title="Zajednički gama lanac">Zajednički γ-lanac</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_2" title="Interleukin 2">2</a>/<a href="/wiki/Interleukin_15" title="Interleukin 15">15</a> •  <a href="/wiki/Interleukin_3" title="Interleukin 3">3</a> •  <a href="/wiki/Interleukin_4" title="Interleukin 4">4</a> •  <a href="/wiki/Interleukin_7" title="Interleukin 7">7</a> •  <a href="/wiki/Interleukin_9" title="Interleukin 9">9</a> •  <a href="/wiki/Interleukin_13" title="Interleukin 13">13</a> •  <a href="/wiki/Interleukin_21" title="Interleukin 21">21</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-12" class="mw-disambig" title="IL-12">IL-12</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_12" title="Interleukin 12">12</a> (<a href="/wiki/Interleukin_12B" title="Interleukin 12B">B</a>) •  <a href="/wiki/Interleukin_23" title="Interleukin 23">23</a> •  <a href="/wiki/Interleukin_27" title="Interleukin 27">27</a> •  <a class="mw-selflink selflink">35</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">Drugi</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_5" title="Interleukin 5">5</a> •  <a href="/wiki/Interleukin_8" title="Interleukin 8">8</a> •  <a href="/wiki/Interleukin_14" title="Interleukin 14">14</a> •  <a href="/wiki/Interleukin_16" title="Interleukin 16">16</a> •  <a href="/wiki/Interleukin_17" title="Interleukin 17">17</a>/<a href="/wiki/Interleukin_25" title="Interleukin 25">25</a> (<a href="/wiki/Interleukin_17A" title="Interleukin 17A">A</a>) •  <a href="/wiki/Interleukin_32" title="Interleukin 32">32</a>  •  <a href="/wiki/Interleukin_34" title="Interleukin 34">34</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Hemokini" class="mw-redirect" title="Hemokini">Hemokini</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CCL</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CCL1" title="CCL1">1</a> •  <a href="/wiki/CCL2" title="CCL2">2</a> •  <a href="/wiki/Makrofagni_inflamatorni_protein" title="Makrofagni inflamatorni protein">3</a> •  <a href="/wiki/CCL4" title="CCL4">4</a> •  <a href="/wiki/CCL5" title="CCL5">5</a> •  <a href="/wiki/CCL6" title="CCL6">6</a> •  <a href="/wiki/CCL7" title="CCL7">7</a> •  <a href="/wiki/CCL8" title="CCL8">8</a> •  <a href="/wiki/CCL9" title="CCL9">9</a> •  <a href="/wiki/CCL9" title="CCL9">10</a> •  <a href="/wiki/CCL11" title="CCL11">11</a> •  <a href="/wiki/CCL12" title="CCL12">12</a> •  <a href="/wiki/CCL13" title="CCL13">13</a> •  <a href="/wiki/CCL14" title="CCL14">14</a> •  <a href="/wiki/CCL15" title="CCL15">15</a> •  <a href="/wiki/CCL16" title="CCL16">16</a> •  <a href="/wiki/CCL17" title="CCL17">17</a> •  <a href="/wiki/CCL18" title="CCL18">18</a> •  <a href="/wiki/CCL19" title="CCL19">19</a> •  <a href="/wiki/CCL20" title="CCL20">20</a> •  <a href="/wiki/CCL21" title="CCL21">21</a> •  <a href="/wiki/CCL22" title="CCL22">22</a> •  <a href="/wiki/CCL23" title="CCL23">23</a> •  <a href="/wiki/CCL24" title="CCL24">24</a> •  <a href="/wiki/CCL25" title="CCL25">25</a> •  <a href="/wiki/CCL26" title="CCL26">26</a> •  <a href="/wiki/CCL27" title="CCL27">27</a> •  <a href="/wiki/CCL28" title="CCL28">28</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CXCL</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CXCL1" title="CXCL1">1</a> •  <a href="/wiki/CXCL2" title="CXCL2">2</a> •  <a href="/wiki/CXCL3" title="CXCL3">3</a> •  <a href="/wiki/Trombocit_faktor_4" title="Trombocit faktor 4">4</a> •  <a href="/wiki/CXCL5" title="CXCL5">5</a> •  <a href="/wiki/CXCL6" title="CXCL6">6</a> •  <a href="/wiki/CXCL7" title="CXCL7">7</a> •  <a href="/wiki/Interleukin_8" title="Interleukin 8">8</a> •  <a href="/wiki/CXCL9" title="CXCL9">9</a> •  <a href="/wiki/CXCL10" title="CXCL10">10</a> •  <a href="/wiki/CXCL11" title="CXCL11">11</a> •  <a href="/wiki/CXCL12" title="CXCL12">12</a> •  <a href="/wiki/CXCL13" title="CXCL13">13</a> •  <a href="/wiki/CXCL14" title="CXCL14">14</a> •  <a href="/wiki/CXCL15" title="CXCL15">15</a> •  <a href="/wiki/CXCL16" title="CXCL16">16</a> •  <a href="/wiki/CXCL17" title="CXCL17">17</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CX3CL</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CX3CL1" title="CX3CL1">1</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">XCL</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/XCL1" title="XCL1">1</a> •  <a href="/wiki/XCL2" title="XCL2">2</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Faktori_nekroze_tumora" title="Faktori nekroze tumora">TNF</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">Glavni</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF-alfa</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">TNF (<a href="/wiki/Ligand_(biohemija)" title="Ligand (biohemija)">ligand</a>) superfamilija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/4-1BB_ligand" title="4-1BB ligand">4-1BB ligand</a> •  <a href="/wiki/Faktor_aktivacije_B-%C4%87elija" title="Faktor aktivacije B-ćelija">Faktor aktivacije B-ćelija</a> •  <a href="/wiki/Fas_ligand" title="Fas ligand">FAS ligand</a> •  <a href="/wiki/Limfotoksin" title="Limfotoksin">Limfotoksin</a> •  <a href="/wiki/OX40L" title="OX40L">OX40L</a> •  <a href="/wiki/RANKL" title="RANKL">RANKL</a> •  <a href="/wiki/TRAIL" title="TRAIL">TRAIL</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Klaster_diferencijacije" title="Klaster diferencijacije">Klaster diferencijacije</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CD70" title="CD70">CD70</a> •  <a href="/wiki/CD153" title="CD153">CD153</a> •  <a href="/wiki/CD154" title="CD154">CD154</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon" title="Interferon">Interferon</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_I" title="Interferon tip I">I</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em">alfa ( <a href="/wiki/Pegilirani_interferon_alfa-2a" title="Pegilirani interferon alfa-2a">Pegilirani 2a</a>, <a href="/wiki/Pegilirani_interferon_alfa-2b" title="Pegilirani interferon alfa-2b">Pegilirani 2b</a>), beta (<a href="/wiki/Interferon_beta-1a" title="Interferon beta-1a">1a</a>, <a href="/wiki/Interferon_beta-1b" title="Interferon beta-1b">1b</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_II" title="Interferon tip II">II</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interferon-gama" title="Interferon-gama">Gama</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">III</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_28" title="Interleukin 28">IL-28</a> •  <a href="/wiki/Interleukin_29" title="Interleukin 29">IL-29</a></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Monokin" title="Monokin">Monokin</a> •  <a href="/wiki/Limfokin" title="Limfokin">Limfokin</a> (<a href="/wiki/Limfotoksin" title="Limfotoksin">Limfotoksin</a>, <a href="/wiki/Faktor_transfera" title="Faktor transfera">Faktor transfera</a>) •  <a href="/wiki/Faktor_rasta" title="Faktor rasta">Faktor rasta</a> •  <a href="/wiki/Hematopoeza" title="Hematopoeza">Hematopoeza</a> (<a href="/wiki/Faktor_stem_%C4%87elija" title="Faktor stem ćelija">Faktor stem ćelija</a>, <a href="/wiki/Faktor_stimulacije_kolonije" title="Faktor stimulacije kolonije">Faktor stimulacije kolonije</a>) •  <a href="/wiki/GPI_(gen)" title="GPI (gen)">Faktor autokrinog motiliteta</a> •  <a href="/wiki/Osteopontin" title="Osteopontin">Osteopontin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Po funkciji</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><i><a href="/wiki/Proinflamatorni_citokin" title="Proinflamatorni citokin">proinflamatorni citokin</a></i> (<a href="/wiki/Interleukin_1" title="Interleukin 1">IL-1</a>, <a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF-alfa</a>) •  <a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>h</sub>1</i></a> (<a href="/wiki/Interferon-gama" title="Interferon-gama">INF-gama</a> i <a href="/wiki/Faktor_nekroze_tumora-beta" class="mw-redirect" title="Faktor nekroze tumora-beta">TNF-beta</a>) •  <a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>h</sub>2</i></a> (<a href="/wiki/Interleukin_4" title="Interleukin 4">IL-4</a>, <a href="/wiki/Interleukin_5" title="Interleukin 5">IL-5</a>, <a href="/wiki/Interleukin_6" title="Interleukin 6">IL-6</a>, <a href="/wiki/Interleukin_10" title="Interleukin 10">IL-10</a>, <a href="/wiki/Interleukin_13" title="Interleukin 13">IL-13</a>) •  <a href="/wiki/T_pomo%C4%87ne_17_%C4%87elije" title="T pomoćne 17 ćelije"><i>T<sub>h</sub>17</i></a> (<a href="/wiki/Interleukin_17" title="Interleukin 17">IL-17</a>,<a href="/wiki/Interleukin_22" title="Interleukin 22">IL-22</a>)</div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite"><div><i><a href="/wiki/%C5%A0ablon:Biohemija_metanavs-lat" title="Šablon:Biohemija metanavs-lat">B</a> <a href="/wiki/%C5%A0ablon:Prenos_signala-lat" title="Šablon:Prenos signala-lat">trdu</a>: <a href="/w/index.php?title=%C5%A0ablon:Intercelularni_signalni_peptidi_i_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Intercelularni signalni peptidi i proteini-lat (stranica ne postoji)">peptidi</a> (<a href="/wiki/%C5%A0ablon:Neuropeptidi-lat" title="Šablon:Neuropeptidi-lat">nrpl</a>/<a href="/wiki/%C5%A0ablon:Faktori_rasta-lat" title="Šablon:Faktori rasta-lat">grfl</a>/<a href="/wiki/%C5%A0ablon:Citokini-lat" title="Šablon:Citokini-lat">cytl</a>/<a href="/wiki/%C5%A0ablon:Hormoni-lat" title="Šablon:Hormoni-lat">horl</a>), <a href="/w/index.php?title=%C5%A0ablon:Receptori_%C4%87elijske_povr%C5%A1ine-lat&action=edit&redlink=1" class="new" title="Šablon:Receptori ćelijske površine-lat (stranica ne postoji)">receptori</a> (<a href="/w/index.php?title=%C5%A0ablon:Ligand-kontrolisani_jonski_kanali-lat&action=edit&redlink=1" class="new" title="Šablon:Ligand-kontrolisani jonski kanali-lat (stranica ne postoji)">lgic</a>, <a href="/w/index.php?title=%C5%A0ablon:Enzim-vezani_receptori-lat&action=edit&redlink=1" class="new" title="Šablon:Enzim-vezani receptori-lat (stranica ne postoji)">enzr</a>, <a href="/wiki/%C5%A0ablon:G_protein_spregnuti_receptori-lat" title="Šablon:G protein spregnuti receptori-lat">gprc</a>, <a href="/wiki/%C5%A0ablon:Imunoglobulinska_superfamilija_imunskih_receptora-lat" title="Šablon:Imunoglobulinska superfamilija imunskih receptora-lat">igsr</a>, <a href="/w/index.php?title=%C5%A0ablon:Integrini-lat&action=edit&redlink=1" class="new" title="Šablon:Integrini-lat (stranica ne postoji)">intg</a>, <a href="/wiki/%C5%A0ablon:Neuropeptidni_receptori-lat" title="Šablon:Neuropeptidni receptori-lat">nrpr</a>/<a href="/wiki/%C5%A0ablon:Receptori_faktora_rasta-lat" title="Šablon:Receptori faktora rasta-lat">grfr</a>/<a href="/wiki/%C5%A0ablon:Citokinski_receptori-lat" class="mw-redirect" title="Šablon:Citokinski receptori-lat">cytr</a>), <a href="/w/index.php?title=%C5%A0ablon:Intracelularni_signalni_peptidi_i_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Intracelularni signalni peptidi i proteini-lat (stranica ne postoji)">itra</a> (<a href="/w/index.php?title=%C5%A0ablon:Adapterski_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Adapterski proteini-lat (stranica ne postoji)">adap</a>, <a href="/wiki/%C5%A0ablon:Regulatori_GTP-vezuju%C4%87ih_proteina-lat" title="Šablon:Regulatori GTP-vezujućih proteina-lat">gbpr</a>, <a href="/w/index.php?title=%C5%A0ablon:Aktivacija_MAP_kinaze-lat&action=edit&redlink=1" class="new" title="Šablon:Aktivacija MAP kinaze-lat (stranica ne postoji)">mapk</a>), <a href="/w/index.php?title=%C5%A0ablon:Kalcjiumska_signalizacija-lat&action=edit&redlink=1" class="new" title="Šablon:Kalcjiumska signalizacija-lat (stranica ne postoji)">calc</a>, <a href="/wiki/%C5%A0ablon:Lipidna_signalizacija-lat" title="Šablon:Lipidna signalizacija-lat">lipd</a>, signalni putevi (<a href="/w/index.php?title=%C5%A0ablon:Hedgehog_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Hedgehog signalni put-lat (stranica ne postoji)">hedp</a>, <a href="/w/index.php?title=%C5%A0ablon:Wnt_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Wnt signalni put-lat (stranica ne postoji)">wntp</a>, <a href="/w/index.php?title=%C5%A0ablon:TGF_beta_signalizacija-lat&action=edit&redlink=1" class="new" title="Šablon:TGF beta signalizacija-lat (stranica ne postoji)">tgfp</a>+<a href="/wiki/%C5%A0ablon:MAPK_ERK_signalni_put-lat" title="Šablon:MAPK ERK signalni put-lat">mapp</a>, <a href="/w/index.php?title=%C5%A0ablon:Notch_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Notch signalni put-lat (stranica ne postoji)">notp</a>, <a href="/w/index.php?title=%C5%A0ablon:JAK-STAT_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:JAK-STAT signalni put-lat (stranica ne postoji)">jakp</a>, <a href="/wiki/%C5%A0ablon:Apoptozni_signalni_put-lat" title="Šablon:Apoptozni signalni put-lat">fsap</a>, <a href="/w/index.php?title=%C5%A0ablon:Hippo_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Hippo signalni put-lat (stranica ne postoji)">hipp</a>, <a href="/w/index.php?title=%C5%A0ablon:TLR_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:TLR signalni put-lat (stranica ne postoji)">tlrp</a>)</i></div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: 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