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Teràpia de substitució de nicotina - Viquipèdia, l'enciclopèdia lliure
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Disponible en 21 llengües" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-21" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">21 llengües</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%85%D8%B9%D8%A7%D9%84%D8%AC%D8%A9_%D8%A7%D9%84%D9%86%D9%8A%D9%83%D9%88%D8%AA%D9%8A%D9%86_%D8%A8%D8%A7%D9%84%D8%A5%D8%B9%D8%A7%D8%B6%D8%A9" title="معالجة النيكوتين بالإعاضة - àrab" lang="ar" hreflang="ar" data-title="معالجة النيكوتين بالإعاضة" data-language-autonym="العربية" data-language-local-name="àrab" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%A8%E0%A6%BF%E0%A6%95%E0%A7%8B%E0%A6%9F%E0%A6%BF%E0%A6%A8_%E0%A6%AA%E0%A7%8D%E0%A6%B0%E0%A6%A4%E0%A6%BF%E0%A6%B8%E0%A7%8D%E0%A6%A5%E0%A6%BE%E0%A6%AA%E0%A6%A8_%E0%A6%A5%E0%A7%87%E0%A6%B0%E0%A6%BE%E0%A6%AA%E0%A6%BF" title="নিকোটিন প্রতিস্থাপন থেরাপি - bengalí" lang="bn" hreflang="bn" data-title="নিকোটিন প্রতিস্থাপন থেরাপি" data-language-autonym="বাংলা" data-language-local-name="bengalí" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Therapi_amnewid_nicotin" title="Therapi amnewid nicotin - gal·lès" lang="cy" hreflang="cy" data-title="Therapi amnewid nicotin" data-language-autonym="Cymraeg" data-language-local-name="gal·lès" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Nikotinersatztherapie" title="Nikotinersatztherapie - alemany" lang="de" hreflang="de" data-title="Nikotinersatztherapie" data-language-autonym="Deutsch" data-language-local-name="alemany" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%A5%CF%80%CE%BF%CE%BA%CE%B1%CF%84%CE%AC%CF%83%CF%84%CE%B1%CF%84%CE%B1_%CE%BD%CE%B9%CE%BA%CE%BF%CF%84%CE%AF%CE%BD%CE%B7%CF%82" title="Υποκατάστατα νικοτίνης - grec" lang="el" hreflang="el" data-title="Υποκατάστατα νικοτίνης" data-language-autonym="Ελληνικά" data-language-local-name="grec" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Nicotine_replacement_therapy" title="Nicotine replacement therapy - anglès" lang="en" hreflang="en" data-title="Nicotine replacement therapy" data-language-autonym="English" data-language-local-name="anglès" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Terapias_de_reemplazo_de_nicotina" title="Terapias de reemplazo de nicotina - espanyol" lang="es" hreflang="es" data-title="Terapias de reemplazo de nicotina" data-language-autonym="Español" data-language-local-name="espanyol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%AF%D8%B1%D9%85%D8%A7%D9%86_%D8%AC%D8%A7%DB%8C%DA%AF%D8%B2%DB%8C%D9%86%DB%8C_%D9%86%DB%8C%DA%A9%D9%88%D8%AA%DB%8C%D9%86" title="درمان جایگزینی نیکوتین - persa" lang="fa" hreflang="fa" data-title="درمان جایگزینی نیکوتین" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Substitut_nicotinique" title="Substitut nicotinique - francès" lang="fr" hreflang="fr" data-title="Substitut nicotinique" data-language-autonym="Français" data-language-local-name="francès" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%98%D7%99%D7%A4%D7%95%D7%9C%D7%99_%D7%94%D7%97%D7%9C%D7%A4%D7%AA_%D7%A0%D7%99%D7%A7%D7%95%D7%98%D7%99%D7%9F" title="טיפולי החלפת ניקוטין - hebreu" lang="he" hreflang="he" data-title="טיפולי החלפת ניקוטין" data-language-autonym="עברית" data-language-local-name="hebreu" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E7%A6%81%E7%85%99%E3%82%B0%E3%83%83%E3%82%BA" title="禁煙グッズ - japonès" lang="ja" hreflang="ja" data-title="禁煙グッズ" data-language-autonym="日本語" data-language-local-name="japonès" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%A8%E0%B4%BF%E0%B4%95%E0%B5%8D%E0%B4%95%E0%B5%8B%E0%B4%9F%E0%B5%8D%E0%B4%9F%E0%B4%BF%E0%B5%BB_%E0%B4%AA%E0%B5%8D%E0%B4%B0%E0%B4%A4%E0%B4%BF%E0%B4%A8%E0%B4%BF%E0%B4%A7%E0%B4%BE%E0%B4%A8_%E0%B4%9A%E0%B4%BF%E0%B4%95%E0%B4%BF%E0%B4%A4%E0%B5%8D%E0%B4%B8" title="നിക്കോട്ടിൻ പ്രതിനിധാന ചികിത്സ - malaiàlam" lang="ml" hreflang="ml" data-title="നിക്കോട്ടിൻ പ്രതിനിധാന ചികിത്സ" data-language-autonym="മലയാളം" data-language-local-name="malaiàlam" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Nicotinevervangingstherapie" title="Nicotinevervangingstherapie - neerlandès" lang="nl" hreflang="nl" data-title="Nicotinevervangingstherapie" data-language-autonym="Nederlands" data-language-local-name="neerlandès" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%A8%E0%AC%BF%E0%AC%95%E0%AD%8B%E0%AC%9F%E0%AC%BF%E0%AC%A8_%E0%AC%AA%E0%AD%81%E0%AC%A8%E0%AC%83%E0%AC%B8%E0%AD%8D%E0%AC%A5%E0%AC%BE%E0%AC%AA%E0%AC%A8_%E0%AC%9A%E0%AC%BF%E0%AC%95%E0%AC%BF%E0%AC%A4%E0%AD%8D%E0%AC%B8%E0%AC%BE" title="ନିକୋଟିନ ପୁନଃସ୍ଥାପନ ଚିକିତ୍ସା - oriya" lang="or" hreflang="or" data-title="ନିକୋଟିନ ପୁନଃସ୍ଥାପନ ଚିକିତ୍ସା" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="oriya" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9D%D0%B8%D0%BA%D0%BE%D1%82%D0%B8%D0%BD%D0%B7%D0%B0%D0%BC%D0%B5%D1%81%D1%82%D0%B8%D1%82%D0%B5%D0%BB%D1%8C%D0%BD%D0%B0%D1%8F_%D1%82%D0%B5%D1%80%D0%B0%D0%BF%D0%B8%D1%8F" title="Никотинзаместительная терапия - rus" lang="ru" hreflang="ru" data-title="Никотинзаместительная терапия" data-language-autonym="Русский" data-language-local-name="rus" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Nicotine_replacement_therapy" title="Nicotine replacement therapy - Simple English" lang="en-simple" hreflang="en-simple" data-title="Nicotine replacement therapy" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Nikotinsko_nadomestno_zdravljenje" title="Nikotinsko nadomestno zdravljenje - eslovè" lang="sl" hreflang="sl" data-title="Nikotinsko nadomestno zdravljenje" data-language-autonym="Slovenščina" data-language-local-name="eslovè" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Nikotin_replasman_tedavisi" title="Nikotin replasman tedavisi - turc" lang="tr" hreflang="tr" data-title="Nikotin replasman tedavisi" data-language-autonym="Türkçe" data-language-local-name="turc" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9D%D1%96%D0%BA%D0%BE%D1%82%D0%B8%D0%BD%D0%BE%D0%B7%D0%B0%D0%BC%D1%96%D1%81%D0%BD%D0%B0_%D1%82%D0%B5%D1%80%D0%B0%D0%BF%D1%96%D1%8F" title="Нікотинозамісна терапія - ucraïnès" lang="uk" hreflang="uk" data-title="Нікотинозамісна терапія" data-language-autonym="Українська" data-language-local-name="ucraïnès" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Li%E1%BB%87u_ph%C3%A1p_thay_th%E1%BA%BF_nicotine" title="Liệu pháp thay thế nicotine - vietnamita" lang="vi" hreflang="vi" data-title="Liệu pháp thay thế nicotine" data-language-autonym="Tiếng Việt" data-language-local-name="vietnamita" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%B0%BC%E5%8F%A4%E4%B8%81%E5%8F%96%E4%BB%A3%E7%99%82%E6%B3%95" title="尼古丁取代療法 - xinès" lang="zh" hreflang="zh" data-title="尼古丁取代療法" data-language-autonym="中文" data-language-local-name="xinès" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q1189783#sitelinks-wikipedia" title="Modifica enllaços interlingües" class="wbc-editpage">Modifica els enllaços</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> 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class="vector-page-tools-landmark" aria-label="Eines de la pàgina"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Aparença"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Aparença</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">mou a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">amaga</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">De la Viquipèdia, l'enciclopèdia lliure</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="ca" dir="ltr"><figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Fitxer:Nicoderm.JPG" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/Nicoderm.JPG/220px-Nicoderm.JPG" decoding="async" width="220" height="146" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/Nicoderm.JPG/330px-Nicoderm.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/94/Nicoderm.JPG/440px-Nicoderm.JPG 2x" data-file-width="3008" data-file-height="2000" /></a><figcaption>Un pegat de nicotina aplicat al braç esquerre</figcaption></figure> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Fitxer:Nicotine_pastille.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/02/Nicotine_pastille.jpg/220px-Nicotine_pastille.jpg" decoding="async" width="220" height="293" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/02/Nicotine_pastille.jpg/330px-Nicotine_pastille.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/02/Nicotine_pastille.jpg/440px-Nicotine_pastille.jpg 2x" data-file-width="1989" data-file-height="2652" /></a><figcaption>Pastilles de nicotina utilitzats en el tractament</figcaption></figure> <p>La <b>teràpia de substitució de nicotina</b> (comunament abreujat a TSN) és una manera d'administrar <a href="/wiki/Nicotina" title="Nicotina">nicotina</a> al cos per mitjans diferents del <a href="/wiki/Tabac" title="Tabac">tabac</a>. S'utilitza per disminuir els <a href="/wiki/S%C3%ADndrome_d%27abstin%C3%A8ncia" title="Síndrome d'abstinència">símptomes d'abstinència</a> provocats per <a href="/wiki/Cessaci%C3%B3_tab%C3%A0quica" title="Cessació tabàquica">deixar de fumar</a> o, rarament, de mastegar el tabac.<sup id="cite_ref-Stead2012_1-0" class="reference"><a href="#cite_note-Stead2012-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>La teràpia de substitució de nicotina redueix el <a href="/wiki/Deler_(drogoaddicci%C3%B3)" title="Deler (drogoaddicció)">deler</a> (o desig compulsiu de tornar a experimentar els efectes d'una substància a la qual s'és addicte) causat per l'addicció a la nicotina en els fumadors i mastegadors, en ajudar a deixar el tabac s'eviten gran part dels efectes nocius del tabac. L'hàbit de fumar i mastegar és alhora una conducta apresa i una addicció física a la nicotina, per tant, l'ús conjunt de productes de substitució de nicotina i l'assessorament poden ajudar els que tracten de deixar de fumar.<sup id="cite_ref-Rigotti_2-0" class="reference"><a href="#cite_note-Rigotti-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> L'ús de la teràpia de substitució de nicotina augmenta l'èxit de deixar de fumar inicialment en un 50 a un 70%.<sup id="cite_ref-Stead2012_1-1" class="reference"><a href="#cite_note-Stead2012-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>Els productes de substitució de nicotina estan en la <a href="/wiki/Llista_model_de_Medicaments_essencials_de_l%27Organitzaci%C3%B3_Mundial_de_la_Salut" title="Llista model de Medicaments essencials de l'Organització Mundial de la Salut">Llista model de Medicaments essencials de l'Organització Mundial de la Salut</a>, una llista dels medicaments més important que es necessita en un sistema bàsic de salut.<sup id="cite_ref-World_Health_Organization_3-0" class="reference"><a href="#cite_note-World_Health_Organization-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Existeixen, d'aquests productes, diferents presentacions: pegats, xiclets, pastilles, inhaladors i aerosols nasals. </p> <div class="mw-heading mw-heading2"><h2 id="Mecanisme">Mecanisme</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ter%C3%A0pia_de_substituci%C3%B3_de_nicotina&action=edit&section=1" title="Modifica la secció: Mecanisme"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Els diferents productes de substitució de nicotina varien en el temps que triga la nicotina per entrar al cos i el temps que s'hi està.<sup id="cite_ref-Rigotti_2-1" class="reference"><a href="#cite_note-Rigotti-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>Els <a href="/wiki/Pegat_de_nicotina" title="Pegat de nicotina">pegats de nicotina</a> s'apliquen a la pell i administren contínuament una dosi estable de nicotina lentament durant 16-24 hores.<sup id="cite_ref-Rigotti_2-2" class="reference"><a href="#cite_note-Rigotti-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Oncken_4-0" class="reference"><a href="#cite_note-Oncken-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> El <a href="/wiki/Xiclet_de_nicotina" title="Xiclet de nicotina">xiclet de nicotina</a>, l'aerosol de nicotina, els comprimits <a href="/wiki/Via_sublingual" title="Via sublingual">sublinguals</a> de nicotina, les pastilles de nicotina s'administren per <a href="/wiki/Via_oral" title="Via oral">via oral</a> amb una absorció més ràpida de nicotina en el cos, però que no dura gaire temps. Els inhaladors de nicotina que administren una dosi establerta de nicotina que s'absorbeix ràpidament a través dels pulmons i les membranes mucoses de la gola, i que també que no dura gaire temps. Per exemple, els nivells de nicotina a la sang són els més alts 5-10 minuts després d'usar l'esprai nasal de nicotina, 20 minuts després d'utilitzar un inhalador de nicotina o un xiclet de mastegar de nicotina, i 2-4 hores després d'usar un pegat de nicotina.<sup id="cite_ref-Rigotti_2-3" class="reference"><a href="#cite_note-Rigotti-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Marques_comercials">Marques comercials</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ter%C3%A0pia_de_substituci%C3%B3_de_nicotina&action=edit&section=2" title="Modifica la secció: Marques comercials"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>A l'estat espanyol està comercialitzat amb els noms Nicorette (polvoritzadors 1mg, pegats 10, 15mg/16h, xiclets 2, 4mg), Nicotinell (xiclets 2 i 4mg), Niquitin (pegats 7, 14 i 21mg/24h, xiclets 1,5, 2 i 4mg) i Quitt (xiclets 2 i 4mg).<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Referències"><span id="Refer.C3.A8ncies"></span>Referències</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Ter%C3%A0pia_de_substituci%C3%B3_de_nicotina&action=edit&section=3" title="Modifica la secció: Referències"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r33663753">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:#f9f9f9;display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 0.9em 2px 0;text-align:center}@media(min-width:500px){.mw-parser-output .side-box-flex{display:flex;align-items:center}.mw-parser-output .side-box-text{flex:1;min-width:0}}@media(min-width:720px){.mw-parser-output .side-box{width:238px}.mw-parser-output .side-box-right{clear:right;float:right;margin-left:1em}.mw-parser-output .side-box-left{margin-right:1em}.mw-parser-output .side-box-center{clear:both;margin:auto}}</style><div class="side-box metadata side-box-right plainlinks"> <div class="side-box-flex"> <div class="side-box-image"><span typeof="mw:File"><span><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png" decoding="async" width="30" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/45px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/59px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></span></span></div> <div class="side-box-text plainlist">A <span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/P%C3%A0gina_principal?uselang=ca">Wikimedia Commons</a></span> hi ha contingut multimèdia relatiu a: <i><b><a href="https://commons.wikimedia.org/wiki/Category:Nicotine_replacement_therapy" class="extiw" title="commons:Category:Nicotine replacement therapy">Teràpia de substitució de nicotina</a></b></i></div></div> </div> <div class="reflist {{#if: | references-column-count references-column-count-{{{col}}}" style="list-style-type: decimal;"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-Stead2012-1"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-Stead2012_1-0">1,0</a></sup> <sup><a href="#cite_ref-Stead2012_1-1">1,1</a></sup></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFStead2012"><span style="font-variant: small-caps;">Stead</span>, LF; Perera, R; Bullen, C; Mant, D; Hartmann-Boyce, J «Nicotine replacement therapy for smoking cessation». <i>The Cochrane database of systematic reviews</i>, 11, 14-11-2012, pàg. CD000146. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002%2F14651858.CD000146.pub4">10.1002/14651858.CD000146.pub4</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/23152200?dopt=Abstract" class="extiw" title="pmid:23152200">23152200</a>.</span></span> </li> <li id="cite_note-Rigotti-2"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-Rigotti_2-0">2,0</a></sup> <sup><a href="#cite_ref-Rigotti_2-1">2,1</a></sup> <sup><a href="#cite_ref-Rigotti_2-2">2,2</a></sup> <sup><a href="#cite_ref-Rigotti_2-3">2,3</a></sup></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFRigotti2002"><span style="font-variant: small-caps;">Rigotti</span>, NA «Clinical practice. Treatment of tobacco use and dependence.». <i>The New England Journal of Medicine</i>, 346, 7, 2-2002, pàg. 506–12. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1056%2Fnejmcp012279">10.1056/nejmcp012279</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/11844853?dopt=Abstract" class="extiw" title="pmid:11844853">11844853</a>.</span></span> </li> <li id="cite_note-World_Health_Organization-3"><span class="mw-cite-backlink"><a href="#cite_ref-World_Health_Organization_3-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal">«<a rel="nofollow" class="external text" href="http://apps.who.int/iris/bitstream/10665/93142/1/EML_18_eng.pdf?ua=1">WHO Model List of EssentialMedicines</a>». <i>World Health Organization</i>, 01-10-2013. [Consulta: 22 abril 2014].</span></span> </li> <li id="cite_note-Oncken-4"><span class="mw-cite-backlink"><a href="#cite_ref-Oncken_4-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFOncken,_MD,_MPHDornelas,_Ph.D.Kranzler_MD2014"><span style="font-variant: small-caps;">Oncken, MD, MPH</span>, Cheryl; <span style="font-variant: small-caps;">Dornelas, Ph.D.</span>, Ellen; <span style="font-variant: small-caps;">Kranzler MD</span>, Henry «Nicotine Gum for Pregnant Smokers». <i>Obstetrics</i>, 112, 4, 28-10-2014, pàg. 859–867. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1097%2FAOG.0b013e318187e1ec">10.1097/AOG.0b013e318187e1ec</a>. <a href="/wiki/PubMed" title="PubMed">PMC</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630492">2630492</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/18827129?dopt=Abstract" class="extiw" title="pmid:18827129">18827129</a>.</span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text">Package insert monograph with Nicorette® inhaler</span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal">«<a rel="nofollow" class="external text" href="https://www.aemps.gob.es/cima/fichasTecnicas.do?metodo=detalleForm">Centro de Información online de Medicamentos de la AEMPS - CIMA</a>».  Madrid:  <a href="/wiki/AEMPS" class="mw-redirect" title="AEMPS">AEMPS</a>. Ministerio de Sanidad, Servicios Sociales e Igualdad, 2024.</span></span> </li> </ol></div></div> <!-- NewPP limit report Parsed by mw‐web.codfw.main‐84d8f4b96‐tmkx8 Cached time: 20241115181041 Cache expiry: 2592000 Reduced expiry: false Complications: [] CPU time usage: 0.138 seconds Real time usage: 0.292 seconds Preprocessor visited node count: 1318/1000000 Post‐expand include size: 9839/2097152 bytes Template argument size: 2740/2097152 bytes Highest expansion depth: 12/100 Expensive parser function count: 0/500 Unstrip recursion depth: 0/20 Unstrip post‐expand size: 6651/5000000 bytes Lua time usage: 0.035/10.000 seconds Lua memory usage: 986860/52428800 bytes Number of Wikibase entities loaded: 0/400 --> <!-- Transclusion expansion time report (%,ms,calls,template) 100.00% 159.374 1 -total 50.95% 81.195 1 Plantilla:Commonscat 49.01% 78.102 1 Plantilla:Referències 46.94% 74.807 1 Plantilla:Sister 45.30% 72.199 1 Plantilla:Caixa_lateral 32.77% 52.222 3 Plantilla:Ref-publicació 19.12% 30.469 5 Plantilla:If_both 8.69% 13.842 2 Plantilla:Ref-web 4.40% 7.011 1 Plantilla:Títol_sense_cua 3.68% 5.867 1 Plantilla:Cita_AEMPS --> <!-- Saved in parser cache with key cawiki:pcache:idhash:1286102-0!canonical and timestamp 20241115181041 and revision id 33687534. 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