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Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern) | School of Biotechnology and Biomolecular Sciences - UNSW Sydney

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src="/content/dam/images/science/babs/websites/2021-10-babs-engage/2021-10-ashton-curry-hyde-and-archie-7.cropimg.width=335.crop=video.jpg" alt="Ashton Curry-Hyde with Archie" loading="lazy" data-aem-asset-id="e4ec0e77-1611-42ee-aa31-dbec51869eba" data-trackable="true" title="Ashton Curry-Hyde with Archie"/> </picture> </div> </div> </div> </div> </div> </div> </span></div> <div class="column-layout uds-component padded-left padded-right padded-left__small--0 padded-right__small--0 aem-GridColumn aem-GridColumn--default--12"> <span data-component_type="column-layout" data-component_id="column_layout_copy-974079607" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12"> <div class="responsivegrid aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--medium--12 aem-GridColumn--small--12 aem-GridColumn--offset--default--0"> <div class="text uds-component section"> <span data-component_type="text" data-component_id="text_copy-1637377595" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-text"> <p><span class="lead-small">Who would have thought that your precious furry friend could open doors in biotechnology? Ashton’s Archie did just that.</span></p> </div> </span> </div> <div class="spacer section"> <span data-component_type="spacer" data-component_id="spacer_copy-1423437210" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-spacer__small"></div> </span> </div> </div> </div> </span></div> <div class="column-layout uds-component padded-left padded-right padded-left__small--0 padded-right__small--0 shape-bg-colour--secondary-red shape-bg-window aem-GridColumn aem-GridColumn--default--12"> <span data-component_type="column-layout" data-component_id="column_layout-1271581349" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12"> <div class="responsivegrid aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--medium--12 aem-GridColumn--small--12 aem-GridColumn--offset--default--0"> <div class="spacer section"> <span data-component_type="spacer" data-component_id="spacer-1675157370" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-spacer__small"></div> </span> </div> <div class="text uds-component section"> <span data-component_type="text" data-component_id="text-837516347" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-text"> <p>Through a neighbourly friendship with a fellow dog owner, Ashton Curry-Hyde was able to connect with the CEO of <a href="https://genieus.co/" target="_blank" data-click_category="TextComponentRichText" data-click_id="text_GenieUs Genomics" data-click_title="RichText" data-click_name="GenieUs Genomics">GenieUs Genomics</a>, Matt Keon. The result is a valuable working partnership benefiting Ashton, her PhD research, Ashton’s supervisor <a href="https://research.unsw.edu.au/people/dr-michael-janitz" target="_blank" data-click_category="TextComponentRichText" data-click_id="text_Dr Michael Janitz" data-click_title="RichText" data-click_name="Dr Michael Janitz">Dr Michael Janitz</a>, and GenieUs Genomics.  </p> <p>Fortunately, Matt was aware of the <a href="https://aprintern.org.au/" target="_blank" data-click_category="TextComponentRichText" data-click_id="text_Australian Postgraduate Research Intern Program" data-click_title="RichText" data-click_name="Australian Postgraduate Research Intern Program">Australian Postgraduate Research Intern Program</a> (APR.Intern), developed to connect academic research labs and motivated PhD students with industry partners for short term research projects. The program is supported by the Australian Government Department of Education, Skills and Employment and MTPConnect’s Researcher Exchange and Development within Industry (REDI) initiative. <br /> </p> <p>Ashton’s work with GenieUs Genomics has involved applying the latest techniques in understanding the human genome to find new solutions for the neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS), a form of Motor Neurone Disease. <br /> </p> </div> </span> </div> <div class="spacer section"> <span data-component_type="spacer" data-component_id="spacer_copy_copy-36139821" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-spacer__medium"></div> </span> </div> </div> </div> </span></div> <div class="spacer aem-GridColumn aem-GridColumn--default--12"> <span data-component_type="spacer" data-component_id="spacer_copy_copy-6016372" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-spacer__medium"></div> </span> </div> <div class="column-layout uds-component padded-left padded-right padded-left__small--0 padded-right__small--0 shape-bg-colour--primary-codegrey aem-GridColumn aem-GridColumn--default--12"> <span data-component_type="column-layout" data-component_id="column_layout_189845-107655209" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12"> <div class="responsivegrid aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--medium--12 aem-GridColumn--small--12 aem-GridColumn--offset--default--0"> <div class="spacer section"> <span data-component_type="spacer" data-component_id="spacer_copy_copy_976-1949216356" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-spacer__small"></div> </span> </div> <div class="text uds-component section"> <span data-component_type="text" data-component_id="text-1235692371" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-text"> <blockquote>'My internship has involved analysing somatic variants in the genetic information of humans who suffered from ALS. I am using sequencing data from an ALS patient post-mortem tissue database to quantify the somatic mutation load in the donor tissues (those which are not germline variants (i.e., inherited). This type of analysis on non-inherited mutations is previously unexplored in ALS, meaning the research is providing a potentially novel understanding of ALS and its disease profile. Given the disease is degenerative and terminal, advancing today’s understanding of its typology is important to advance research, prevention and prognostic and treatment outcomes for those who suffer from it. </blockquote> <blockquote>Incorporating this analytical approach into GenieUs Genomics’ bioinformatic assessment tool will assist in the identification of molecular and other risk factors that influence the disease’s expression in ALS patients.' <br /> </blockquote> </div> </span> </div> <div class="spacer section"> <span data-component_type="spacer" data-component_id="spacer_copy_copy-1480245573" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-spacer__medium"></div> </span> </div> </div> </div> </span></div> <div class="column-layout uds-component padded-left padded-right padded-left__small--0 padded-right__small--0 aem-GridColumn aem-GridColumn--default--12"> <span data-component_type="column-layout" data-component_id="column_layout_189845-236265295" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12"> <div class="responsivegrid aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--medium--12 aem-GridColumn--small--12 aem-GridColumn--offset--default--0"> <div class="spacer section"> <span data-component_type="spacer" data-component_id="spacer-1883226630" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-spacer__small"></div> </span> </div> <div class="text uds-component section"> <span data-component_type="text" data-component_id="text-1266782663" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-text"> <p>Ashton reflected on the benefits of the APR.Intern Program. These include: </p> <ul> <li>Support for the research work of her academic supervisor. <br /> </li> <li>Valuable analytical results to aid the development of GenieUs Genomics products. <br /> </li> <li>Experience that has helped Ashton gain insight and a better understanding of the practical research environment and business imperatives driving a project with commercial potential and real benefits for patients. <br /> </li> </ul> </div> </span> </div> <div class="spacer section"> <span data-component_type="spacer" data-component_id="spacer_copy_copy-931793503" data-component_title="Ashton Curry-Hyde: Postgraduate Research Intern Program (APR.Intern)"> <div class="cmp-spacer__medium"></div> </span> </div> </div> </div> </span></div> <div class="column-layout uds-component padded-left padded-right padded-left__small--0 padded-right__small--0 shape-bg-colour--tertiary-sky shape-bg-window aem-GridColumn aem-GridColumn--default--12"> <span data-component_type="column-layout" 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