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class="nav-primary-link menu-item menu-item-type-post_type menu-item-object-page menu-item-6005"><a href="https://somalogic.com/portal-logins/">Login</a><div></li> </ul> <ul id="menu-top-global-1" class="btns-menu"><li class="menu-item search-form"><form role="search" method="get" class="search-form" action="https://somalogic.com/"> <label> <div class="search-bar"> <div class="icon"></div> <div class="input"> <span class="screen-reader-text">Search for:</span> <input type="search" class="search-field" placeholder="Search …" value="" name="s" /> </div> </div> </label> <button type="submit" class="search-submit">Search</button> </form> </li><li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-6067"><a href="#">Global</a></li> </ul> </div> </div> </div> </div> </div> </header> <main class="page-content"> <div class="hero" style="background-image: url(https://somalogic.com/wp-content/uploads/2022/07/Hero_Texture-3-scaled.jpeg);height: 600px;" title="Splash of teal and pink color"> <div class="container"> <div class="grid"> <div class="cell-md-9"> <p class="breadcrumbs"><a href="/">Home</a> / About Us / Intellectual Property / <span class="blue">List of Patents</span></p> <h1>Patents</h1> <p>Our products and vision for the future are based on a deep portfolio of intellectual property unique in this industry.</p> </div> </div> </div> </div><div class="wrap white " id="wrap_0" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-10 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class=""><p>SomaLogic has an extensive intellectual property (IP) estate of issued patents and pending patent applications that provides global protection in the major diagnostic and pharmaceutical markets for nucleic acid based chemistries and the development and use of the company’s proprietary SOMAmer<sup>®</sup> reagents as individual protein binders or as a multiplex library of protein binding reagents (e.g., SomaScan<sup>®</sup> platform).</p> <p>As of November 2022, SomaLogic owns or controls 601 domestic and foreign issued patents, and 332 domestic and foreign pending patent applications.</p> <p>The company’s comprehensive IP estate protects multiple innovative platforms and technologies. Our IP estate is built around four key platform technologies: Chemistry, Detection, SELEX and Data Analytics, and two technology application areas: diagnostics and therapeutics.</p> <p>Details regarding each technology area as it relates to the SomaLogic patent estate are provided below:</p> </div> </div><div class="cards-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0"> <div class=" cards two-columns" ><div class="card white owl-block" title=""> <div> <h3>Chemistry</h3> <div class="content"><ul class="blue-dot"> <li>Library of base modified nucleotides that improve the target binding properties (sensitivity, specificity and off-rate) and nuclease stability of oligonucleotides, and may be used to “tune” the clearance rate of therapeutic oligonucleotides</li> <li>Methods for synthesizing base modified nucleotides</li> <li>Oligonucleotides having a single type or dual type base modified nucleotides (e.g., SOMAmer reagents)</li> </ul> </div> </div> </div><div class="card white owl-block" title=""> <div> <h3>Data Analytics</h3> <div class="content"><ul class="blue-dot"> <li>Methods for assessing pre-analytical variability in a biological sample and its impact on biomarker discovery, diagnostic tests and protein measurements</li> <li>Methods for determining disease risk by combining down-sampling of class-imbalanced data sets with survival analysis</li> <li>Methods for data normalization using an adaptive statistical approach to produce normalization scale factors</li> <li>Methods for normalizing the variability of inter-sample analyte measurements for a biological matrix (e.g., urine)</li> </ul> </div> </div> </div><div class="card white owl-block" title=""> <div> <h3>Detection</h3> <div class="content"><ul class="blue-dot"> <li>Methods for detecting and quantifying a single target or multiple targets in a biological sample with an aptamer (SomaScan platform)</li> <li>Multiple aptamer-based assay formats including a single and multiplex aptamer-based assay, an aptamer sandwich assay and a “beacon” aptamer assay</li> </ul> </div> </div> </div><div class="card white owl-block" title=""> <div> <h3>Diagnostics</h3> <div class="content"><ul class="blue-dot"> <li>Methods for determining the likelihood that an individual has a particular disease or condition</li> <li>Methods for predicting the risk that an individual will have a certain disease or condition</li> <li>Diagnostic and predictive biomarker panels for a particular disease or condition</li> </ul> </div> </div> </div><div class="card white owl-block" title=""> <div> <h3>SELEX</h3> <div class="content"><ul class="blue-dot"> <li>Methods for identifying or developing a nucleic acid aptamer including using a “slow off-rate enrichment” process and oligonucleotides having one or more base modified nucleotides (single type or dual type base modified nucleotides)</li> </ul> </div> </div> </div><div class="card white owl-block" title=""> <div> <h3>Therapeutics</h3> <div class="content"><ul class="blue-dot"> <li>Specific nucleic acid aptamer sequence motifs (“sequence families”)</li> <li>Methods for treating a condition or disease with a nucleic acid aptamer</li> </ul> </div> </div> </div></div> </div><div class="text-block cell-md-10 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class=""><h3>Important links</h3> <p><a href="https://somalogic.com/somascan-patents-trademarks/">SomaScan Assay, SomaScan access and SomaScan deployment patent and trademark notice</a></p> <p><a href="/somamer-reagent-patent-and-trademark-notice/">SOMAmer reagent patent and trademark notice</a></p> </div> </div></div> </div> </div></main> <footer> <div class="footer-top"> <div class="container"> <div class="grid"> <div class="cell-md-6"> <img src="https://somalogic.com/wp-content/themes/soma/img/SomaLogic-SBI-Dual-Logo-White.svg" alt="Somalogic logo" class="footer-logo" /> <p>SomaLogic Operating Co., Inc.<br /> 2945 Wilderness Pl. Boulder, CO 80301</p> <p><img loading="lazy" decoding="async" class="alignnone size-full wp-image-6071" src="https://somalogic.com/wp-content/uploads/2023/10/footerGlobalStatement.svg" alt="This site is intended for a global audience" width="323" height="21" /></p> </div> <div class="cell-md-6"> <div class="connect"> <div>Connect with us</div> <ul> <Li><a href="https://www.facebook.com/SomaLogicInc" aria-label="facebook_link" target="_blank"><span class="icon-facebook"></span></a></li> <Li><a href="https://twitter.com/somalogic" aria-label="twitter_link" target="_blank"><span class="icon-twitter"></span></a></li> <Li><a href="https://www.linkedin.com/company/somalogic/" aria-label="linkedin_link" target="_blank"><span class="icon-linkedin"></span></a></li> </ul> </div> </div> </div> </div> </div> <div class="footer-bottom"> <div class="container"> <div class="grid"> <div class="cell-md-4"> <ul id="menu-footer" class="menu"><li id="menu-item-735" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-735"><a href="https://somalogic.com/terms-of-use/">Terms of Use</a></li> <li id="menu-item-734" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-734"><a href="https://somalogic.com/privacy-policy/">Privacy</a></li> <li id="menu-item-733" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-733"><a href="https://somalogic.com/cookie-policy/">Cookie Policy</a></li> <li id="menu-item-732" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-732"><a href="https://somalogic.com/site-map/">Site Map</a></li> </ul> </div> <div class="cell-md-8"> <strong>For Research Use Only. Not for use in diagnostic procedures.</strong> <br class="desktop" />Patent and License Information:<a style="color:white !important" href="https://www.standardbio.com/legal/notices" target="_blank">www.standardbio.com/legal/salesterms</a>. Trademarks: <a style="color:white !important" href="https://www.standardbio.com/legal/trademarks" target="_blank">www.standardbio.com/legal/trademarks</a>. Any other trademarks are the sole property of their respective owners. ©2024 Standard BioTools Inc. All rights reserved.<br class="desktop" /> <br />SomaLogic, SomaScan, SOMAmer, SomaSignal, DataDelve and associated logos are trademarks of SomaLogic Operating Co., Inc., a wholly owned subsidiary of Standard BioTools Inc. Patent and Trademarks: <a style="color:white !important" href="https://somalogic.com/list-of-patents/">https://somalogic.com/list-of-patents/</a>. Any other trademarks are the sole property of their respective owners. ©2024 Standard BioTools Inc. (f.k.a. Fluidigm Corporation). 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