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</div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Appearance</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" 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div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">In this <a href="/wiki/Hong_Kong_name" title="Hong Kong name">Hong Kong name</a>, the <a href="/wiki/Surname" title="Surname">surname</a> is <i> <a href="/wiki/Lu_(surname_%E7%9B%A7)" title="Lu (surname 盧)">Lo</a></i>. In accordance with Hong Kong custom, the Western-style name is Dennis Lo and the Chinese-style name is Lo Yuk-ming.</div> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox vcard"><tbody><tr><th colspan="2" class="infobox-above" style="font-size: 100%;"><div class="honorific-prefix" style="font-weight: normal;"><a href="/wiki/Professor" title="Professor">Professor</a></div><div class="fn" style="font-size:125%;">Dennis Lo</div><div class="honorific-suffix" style="font-weight: normal;"><span class="nobold noexcerpt nowraplinks" style="font-size:;"><span style="font-size: 100%;"><a href="/wiki/Silver_Bauhinia_Star" title="Silver Bauhinia Star">SBS</a></span> <span style="font-size: 100%;"><a href="/wiki/Justice_of_the_Peace#Hong_Kong" class="mw-redirect" title="Justice of the Peace">JP</a></span></span> <span class="nobold noexcerpt nowraplinks" style="font-size:;"><span style="font-size: 100%;"><a href="/wiki/Fellow_of_the_Royal_Society" title="Fellow of the Royal Society">FRS</a></span> <span style="font-size: 100%;"><a href="/wiki/Fellow_of_the_Royal_College_of_Physicians" class="mw-redirect" title="Fellow of the Royal College of Physicians">FRCP</a></span> <span style="font-size: 100%;"><a href="/wiki/Fellow_of_the_Royal_College_of_Pathologists" class="mw-redirect" title="Fellow of the Royal College of Pathologists">FRCPath</a></span></span><sup id="cite_ref-cuhkmed_1-0" class="reference"><a href="#cite_note-cuhkmed-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-ashk_2-0" class="reference"><a href="#cite_note-ashk-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></div></th></tr><tr><td colspan="2" class="infobox-subheader" style="font-size:125%; font-weight:bold;"><div class="nickname" lang="zh-hk"><style data-mw-deduplicate="TemplateStyles:r886047488">.mw-parser-output .nobold{font-weight:normal}</style><span class="nobold">盧煜明</span></div></td></tr><tr><td colspan="2" class="infobox-image"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:Prof_Dennis_Lo_Yuk_Ming.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Prof_Dennis_Lo_Yuk_Ming.jpg/220px-Prof_Dennis_Lo_Yuk_Ming.jpg" decoding="async" width="220" height="293" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/b/b1/Prof_Dennis_Lo_Yuk_Ming.jpg 1.5x" data-file-width="225" data-file-height="300" /></a></span><div class="infobox-caption" style="line-height:normal;padding-top:0.2em;">Lo attending an academic conference at <a href="/wiki/University_of_Cambridge" title="University of Cambridge">University of Cambridge</a> on 20 April 2023</div></td></tr><tr><td colspan="2" class="infobox-full-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"></td></tr><tr><th colspan="2" class="infobox-header" style="color: #202122; background:lavender;line-height:normal;padding:0.2em;">9th Vice-Chancellor and President of the <a href="/wiki/Chinese_University_of_Hong_Kong" title="Chinese University of Hong Kong">Chinese University of Hong Kong</a></th></tr><tr><td colspan="2" class="infobox-full-data" style="border-bottom:none"><span class="nowrap"><b>Assuming office</b></span><br />8 January 2025</td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"></tr><tr><th scope="row" class="infobox-label" style="text-align:left">Chancellor</th><td class="infobox-data"><a href="/wiki/John_Lee_Ka-chiu" title="John Lee Ka-chiu">John Lee</a></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left">Succeeding</th><td class="infobox-data"><a href="/wiki/Rocky_Tuan" title="Rocky Tuan">Rocky Tuan</a></td></tr><tr style="display:none"><td colspan="2"> </td></tr><tr><th colspan="2" class="infobox-header" style="color: #202122; background:lavender">Personal details</th></tr><tr><th scope="row" class="infobox-label">Born</th><td class="infobox-data"><span style="display:none"> (<span class="bday">1963-10-12</span>) </span>October 12, 1963<span class="noprint ForceAgeToShow"> (age 61)</span><sup id="cite_ref-kingfaisal_3-0" class="reference"><a href="#cite_note-kingfaisal-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><br /><a href="/wiki/British_Hong_Kong" title="British Hong Kong">British Hong Kong</a><sup id="cite_ref-embryo_4-0" class="reference"><a href="#cite_note-embryo-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label">Spouse</th><td class="infobox-data">Alice Siu Ling Wong<sup id="cite_ref-embryo_4-1" class="reference"><a href="#cite_note-embryo-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></td></tr><tr><td colspan="2" class="infobox-full-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"></td></tr><tr><th scope="row" class="infobox-label">Education</th><td class="infobox-data"><a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a> (<a href="/wiki/Doctor_of_Philosophy" title="Doctor of Philosophy">DPhil</a>, <a href="/wiki/Doctor_of_Medicine" title="Doctor of Medicine">DM</a>, <a href="/wiki/Bachelor_of_Medicine_and_Bachelor_of_Surgery" class="mw-redirect" title="Bachelor of Medicine and Bachelor of Surgery">BM BCh</a>)<br /> <a href="/wiki/University_of_Cambridge" title="University of Cambridge">University of Cambridge</a> (<a href="/wiki/Master_of_Arts_(Oxford,_Cambridge,_and_Dublin)" title="Master of Arts (Oxford, Cambridge, and Dublin)">MA</a>)</td></tr><tr><th scope="row" class="infobox-label">Known for</th><td class="infobox-data"><a href="/wiki/Non_invasive_prenatal_testing" class="mw-redirect" title="Non invasive prenatal testing">Non-invasive prenatal testing</a> <br /> <a href="/wiki/Liquid_biopsy" title="Liquid biopsy">Liquid biopsy</a> <br /> <a href="/wiki/Cell-free_fetal_DNA" title="Cell-free fetal DNA">Cell-free fetal DNA</a> detection in <a href="/wiki/Blood_plasma" title="Blood plasma">blood plasma</a></td></tr><tr><th scope="row" class="infobox-label">Awards</th><td class="infobox-data"><a href="/wiki/King_Faisal_Prize" title="King Faisal Prize">King Faisal Prize</a> in <a href="/wiki/Medicine" title="Medicine">Medicine</a> <small>(2014)</small> <br /> <a href="/wiki/Breakthrough_Prize_in_Life_Sciences" title="Breakthrough Prize in Life Sciences">Breakthrough Prize in Life Sciences</a> <small>(2021)</small> <br /> <a href="/wiki/Royal_Medal" title="Royal Medal">Royal Medal</a> <small>(2021)</small> <br /> <a href="/wiki/Lasker-DeBakey_Clinical_Medical_Research_Award" class="mw-redirect" title="Lasker-DeBakey Clinical Medical Research Award">Lasker-DeBakey Clinical Medical Research Award</a> <small>(2022)</small></td></tr><tr><td colspan="2" class="infobox-full-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><b>Scientific career</b></td></tr><tr><th scope="row" class="infobox-label">Fields</th><td class="infobox-data category"><a href="/wiki/Molecular_biology" title="Molecular biology">Molecular biology</a></td></tr><tr><th scope="row" class="infobox-label">Institutions</th><td class="infobox-data"><a href="/wiki/Chinese_University_of_Hong_Kong" title="Chinese University of Hong Kong">Chinese University of Hong Kong</a> <br /> <a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Thesis" title="Thesis">Thesis</a></th><td class="infobox-data"><i><a rel="nofollow" class="external text" href="https://solo.bodleian.ox.ac.uk/permalink/f/89vilt/oxfaleph015886280">Genetic analysis of fetal cells in maternal blood</a></i> <span style="font-size:97%;">(1994)</span></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Doctoral_advisor" title="Doctoral advisor">Doctoral advisor</a></th><td class="infobox-data">Kenneth Anthony Fleming</td></tr><tr style="display:none"><td colspan="2"> </td></tr><tr style="display:none"><td colspan="2"> </td></tr><tr><td colspan="2" class="infobox-below" style="border-top: 1px solid right;"><div></div></td></tr></tbody></table> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above" style="color: #202122;background-color:#b0c4de">Dennis Lo</th></tr><tr style="display:none;"><td colspan="2" class="infobox-full-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"></td></tr><tr><th scope="row" class="infobox-label" style="font-weight:normal;"><a href="/wiki/Traditional_Chinese_characters" title="Traditional Chinese characters">Traditional Chinese</a></th><td class="infobox-data"><span title="Chinese-language text"><span lang="zh-Hant" style="font-size: 1rem;">盧煜明</span></span></td></tr><tr><th scope="row" class="infobox-label" style="font-weight:normal;"><a href="/wiki/Simplified_Chinese_characters" title="Simplified Chinese characters">Simplified Chinese</a></th><td class="infobox-data"><span title="Chinese-language text"><span lang="zh-Hans" style="font-size: 1rem;">卢煜明</span></span></td></tr><tr><td colspan="2" class="infobox-full-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox-subbox mw-collapsible mw-collapsed" style="display:inline-table; text-align: left;"><tbody><tr><th colspan="2" class="infobox-above" style="font-size: 100%; text-align: left;color: #202122; background-color: #f9ffbc;">Transcriptions</th></tr><tr><th colspan="2" class="infobox-header" style="color: #202122;background-color: #dcffc9;"><a href="/wiki/Cantonese" title="Cantonese">Yue: Cantonese</a></th></tr><tr><th scope="row" class="infobox-label" style="font-weight:normal;"><a href="/wiki/Yale_romanization_of_Cantonese" title="Yale romanization of Cantonese">Yale Romanization</a></th><td class="infobox-data"><span title="Yue Chinese-language romanization"><span style="font-style: normal" lang="yue-Latn">Lòuh Yūk Mìhng</span></span></td></tr><tr><th scope="row" class="infobox-label" style="font-weight:normal;"><a href="/wiki/Jyutping" title="Jyutping">Jyutping</a></th><td class="infobox-data"><span title="Yue Chinese-language romanization"><span style="font-style: normal" lang="yue-Latn">Lou<sup>4</sup> Juk<sup>1</sup> Ming<sup>4</sup></span></span></td></tr></tbody></table></td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"></tr><tr style="display:none"><td colspan="2"> </td></tr></tbody></table> <p><b>Dennis Lo Yuk-ming</b><sup id="cite_ref-cuhkmed_1-1" class="reference"><a href="#cite_note-cuhkmed-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> (<a href="/wiki/Traditional_Chinese_characters" title="Traditional Chinese characters">Chinese</a>: <span lang="zh-Hant">盧煜明</span>; <a href="/wiki/Jyutping" title="Jyutping">Jyutping</a>: <i><span lang="yue-Latn-jyutping">Lou4 Juk1 Ming4</span></i>, born 12 October 1963) is a <a href="/wiki/Hong_Kong" title="Hong Kong">Hong Kong</a> <a href="/wiki/Molecular_biologist" class="mw-redirect" title="Molecular biologist">molecular biologist</a>, best known for his contributions to the development of <a href="/wiki/Non_invasive_prenatal_testing" class="mw-redirect" title="Non invasive prenatal testing">non-invasive prenatal testing</a>. His research focuses on the detection of <a href="/wiki/Cell-free_fetal_DNA" title="Cell-free fetal DNA">cell-free fetal DNA</a> in <a href="/wiki/Blood_plasma" title="Blood plasma">blood plasma</a>.<sup id="cite_ref-cuhkchempath_5-0" class="reference"><a href="#cite_note-cuhkchempath-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>Lo is the current <a href="/wiki/Dean_(education)" title="Dean (education)">Associate Dean</a> (Research) and <a href="/wiki/Li_Ka_Shing" class="mw-redirect" title="Li Ka Shing">Li Ka Shing</a> Professor of Medicine at the <a href="/wiki/CUHK_Faculty_of_Medicine" title="CUHK Faculty of Medicine">Faculty of Medicine</a> of the <a href="/wiki/Chinese_University_of_Hong_Kong" title="Chinese University of Hong Kong">Chinese University of Hong Kong</a> (CUHK), where he is also the head of the Department of <a href="/wiki/Chemical_pathology" class="mw-redirect" title="Chemical pathology">Chemical Pathology</a> and the director of the Li Ka Shing Institute of Health Sciences.<sup id="cite_ref-cuhkmed_1-2" class="reference"><a href="#cite_note-cuhkmed-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-cuhkchempath_5-1" class="reference"><a href="#cite_note-cuhkchempath-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>Lo is set to succeed <a href="/wiki/Rocky_Tuan" title="Rocky Tuan">Rocky Tuan</a> as the vice-chancellor and president of CUHK on 8 January 2025, following his nomination as the sole candidate and the unanimous approval of his nomination. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Early_life_and_education">Early life and education</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Dennis_Lo&action=edit&section=1" title="Edit section: Early life and education"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Lo was born in <a href="/wiki/Hong_Kong" title="Hong Kong">Hong Kong</a> in 1963.<sup id="cite_ref-embryo_4-2" class="reference"><a href="#cite_note-embryo-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> His mother taught music and his father, Lo Wai-hoi,<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> who immigrated from <a href="/wiki/Chaozhou" title="Chaozhou">Chaozhou</a> to Hong Kong in 1946,<sup id="cite_ref-ajog_7-0" class="reference"><a href="#cite_note-ajog-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-clinchem_8-0" class="reference"><a href="#cite_note-clinchem-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> was a <a href="/wiki/Psychiatrist" title="Psychiatrist">psychiatrist</a> and the former head of <a href="/wiki/Castle_Peak_Hospital" title="Castle Peak Hospital">Castle Peak Hospital</a>.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> Lo also has a younger brother.<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p><p>Lo attended <a href="/wiki/St_Joseph%27s_College,_Hong_Kong" title="St Joseph's College, Hong Kong">St Joseph's College</a> for his <a href="/wiki/Education_in_Hong_Kong" title="Education in Hong Kong">primary and secondary education</a>. After secondary school, he was accepted by <a href="/wiki/Stanford_University" title="Stanford University">Stanford University</a> for <a href="/wiki/Electrical_engineering" title="Electrical engineering">electrical engineering</a>, and by the <a href="/wiki/University_of_Hong_Kong" title="University of Hong Kong">University of Hong Kong</a> and <a href="/wiki/University_of_Cambridge" title="University of Cambridge">University of Cambridge</a> for <a href="/wiki/Medicine" title="Medicine">medicine</a>. He selected to study medicine abroad.<sup id="cite_ref-ajog_7-1" class="reference"><a href="#cite_note-ajog-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> In 1983, at the age of 20, Lo arrived at Cambridge, where he spent two years completing his preclinical medical training and a <a href="/wiki/Bachelor_of_Arts" title="Bachelor of Arts">BA</a> degree, and his third studying genetic cloning.<sup id="cite_ref-clinchem_8-1" class="reference"><a href="#cite_note-clinchem-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-ouhkhon_11-0" class="reference"><a href="#cite_note-ouhkhon-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> In 1986,<sup id="cite_ref-ouhkhon_11-1" class="reference"><a href="#cite_note-ouhkhon-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Lo moved to the <a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a> for his clinical training, in part, he claimed, thanks to <a href="/wiki/Christopher_Wren" title="Christopher Wren">Christopher Wren's</a> architectural works at Oxford.<sup class="noprint Inline-Template" style="margin-left:0.1em; white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Please_clarify" title="Wikipedia:Please clarify"><span title="Why is his move thanks to these architectural works? What does this mean? (October 2024)">clarification needed</span></a></i>]</sup><sup id="cite_ref-ajog_7-2" class="reference"><a href="#cite_note-ajog-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-clinchem_8-2" class="reference"><a href="#cite_note-clinchem-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> Lo completed his <a href="/wiki/Bachelor_of_Medicine,_Bachelor_of_Surgery" title="Bachelor of Medicine, Bachelor of Surgery">medical degree (BM BCh)</a> in 1989; he was at <a href="/wiki/Christ_Church,_Oxford" title="Christ Church, Oxford">Christ Church College</a> during this period.<sup id="cite_ref-ajog_7-3" class="reference"><a href="#cite_note-ajog-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-oxfordchina_12-0" class="reference"><a href="#cite_note-oxfordchina-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p><p>After obtaining his medical degree, Lo continued to study at Oxford, first obtaining a <a href="/wiki/Doctor_of_Philosophy" title="Doctor of Philosophy">DPhil</a> (during which he was at <a href="/wiki/Hertford_College,_Oxford" title="Hertford College, Oxford">Hertford College</a>) in 1994, and then a <a href="/wiki/Doctor_of_Medicine" title="Doctor of Medicine">Doctor of Medicine</a> (DM) degree in 2001.<sup id="cite_ref-ouhkhon_11-2" class="reference"><a href="#cite_note-ouhkhon-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> He was also a junior research fellow in natural sciences at Hertford College between 1990 and 1993, and the Wellcome Career Development Fellow in Clinical Medicine from 1993 to 1994.<sup id="cite_ref-kingfaisal_3-1" class="reference"><a href="#cite_note-kingfaisal-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Career">Career</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Dennis_Lo&action=edit&section=2" title="Edit section: Career"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Lo began his research career studying <a href="/wiki/Polymerase_chain_reaction" title="Polymerase chain reaction">polymerase chain reaction</a> (PCR), a <a href="/wiki/Molecular_biology" title="Molecular biology">molecular biological</a> technique for rapidly generating millions of copies of a desired <a href="/wiki/DNA" title="DNA">DNA</a> sequence. He first heard about the technique at a lecture by <a href="/wiki/John_Bell_(physician)" title="John Bell (physician)">John Bell</a>, now <a href="/wiki/Regius_Professor_of_Medicine_(Oxford)" title="Regius Professor of Medicine (Oxford)">Regius Professor of Medicine</a>, at Oxford, and asked to learn the technique from Bell.<sup id="cite_ref-ajog_7-4" class="reference"><a href="#cite_note-ajog-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-clinchem_8-3" class="reference"><a href="#cite_note-clinchem-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pnas_13-0" class="reference"><a href="#cite_note-pnas-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> Working with Kenneth Anthony Fleming, his future PhD advisor, Lo found the relatively new technique generated a lot of <a href="/wiki/False_positives" class="mw-redirect" title="False positives">false positives</a> due to contamination.<sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> </p><p>Lo then wondered if <a href="/wiki/Fetus" title="Fetus">fetal</a> DNA was detectable in mother's <a href="/wiki/Blood" title="Blood">blood</a>. Using PCR, he detected the <a href="/wiki/Y_chromosome" title="Y chromosome">Y chromosome</a> in a mother bearing a baby boy.<sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> During his PhD, Lo wanted to develop his research into <a href="/wiki/Prenatal_testing" title="Prenatal testing">prenatal diagnostic test</a>, using fetal DNA from fetal <a href="/wiki/Cell_(biology)" title="Cell (biology)">cells</a> in the mother's blood. This, however, was stymied by a number of factors, including low concentration of fetal cells, high false positive rate and the persistence of fetal cells after giving birth.<sup id="cite_ref-ajog_7-5" class="reference"><a href="#cite_note-ajog-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-clinchem_8-4" class="reference"><a href="#cite_note-clinchem-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p><p>After obtaining his PhD, Lo became a <a href="/wiki/Lecturer" title="Lecturer">lecturer</a> in <a href="/wiki/Clinical_chemistry" title="Clinical chemistry">clinical biochemistry</a> and a fellow at <a href="/wiki/Green_Templeton_College,_Oxford#Green_College" title="Green Templeton College, Oxford">Green College</a>, <a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a> (now part of <a href="/wiki/Green_Templeton_College,_Oxford" title="Green Templeton College, Oxford">Green Templeton College</a>).<sup id="cite_ref-kingfaisal_3-2" class="reference"><a href="#cite_note-kingfaisal-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-ouhkhon_11-3" class="reference"><a href="#cite_note-ouhkhon-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> He was also an honorary consultant <a href="/wiki/Clinical_chemistry" title="Clinical chemistry">chemical pathologist</a> at <a href="/wiki/John_Radcliffe_Hospital" title="John Radcliffe Hospital">John Radcliffe Hospital</a>, the major <a href="/wiki/Teaching_hospital" title="Teaching hospital">teaching hospital</a> for Oxford.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p><p>In 1997, again using the Y chromosome as a marker in mothers bearing baby boys, Lo reported the presence of cell-free fetal DNA in most of the test subjects.<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> This was after he read that <a href="/wiki/Circulating_tumor_DNA" title="Circulating tumor DNA">circulating tumor DNA</a> were detectable in cancer patients' <a href="/wiki/Blood_plasma" title="Blood plasma">blood plasma</a> and switched strategy to search for <a href="/wiki/Cell-free_fetal_DNA" title="Cell-free fetal DNA">cell-free fetal DNA</a> in mother's blood.<sup id="cite_ref-ajog_7-6" class="reference"><a href="#cite_note-ajog-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>Lo, who by the time was married, returned to <a href="/wiki/Hong_Kong" title="Hong Kong">Hong Kong</a> the same year with his wife, as the city was preparing its <a href="/wiki/Handover_of_Hong_Kong" title="Handover of Hong Kong">handing back</a> to <a href="/wiki/China" title="China">China</a>. He became a senior lecturer in the Department of <a href="/wiki/Clinical_chemistry" title="Clinical chemistry">Chemical Pathology</a> at the <a href="/wiki/Chinese_University_of_Hong_Kong" title="Chinese University of Hong Kong">Chinese University of Hong Kong</a> (CUHK) in January 1997.<sup id="cite_ref-clinchem_8-5" class="reference"><a href="#cite_note-clinchem-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> In an interview years later, he called this discovery was like "finding your car's engine somewhere other than under the bonnet."<sup id="cite_ref-guardian_19-0" class="reference"><a href="#cite_note-guardian-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> </p><p>One of the first disorders for which Lo developed <a href="/wiki/Non_invasive_prenatal_testing" class="mw-redirect" title="Non invasive prenatal testing">non-invasive prenatal testing</a> using cell-free fetal DNA was <a href="/wiki/Rh_disease" title="Rh disease">Rh disease</a>, a type of <a href="/wiki/Anaemia" class="mw-redirect" title="Anaemia">anaemia</a> that occurs when the foetus is <a href="/wiki/Rh_blood_group_system" title="Rh blood group system">Rh</a>-positive but the mother is Rh-negative.<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> Separately, Lo also detected fetal <a href="/wiki/RNA" title="RNA">RNA</a> in mother's blood, which indicated what <a href="/wiki/Genes" class="mw-redirect" title="Genes">genes</a> were <a href="/wiki/Gene_expression" title="Gene expression">expressed</a>.<sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> He then sought novel methods to isolate fetal DNA from mother's blood, which in 2002 came in the form of difference in <a href="/wiki/DNA_methylation" title="DNA methylation">DNA methylation</a> between the mother and foetus.<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> </p><p>Lo's research into non-invasive prenatal testing was interrupted in 2003 by the <a href="/wiki/2002%E2%80%932004_SARS_outbreak" title="2002–2004 SARS outbreak">SARS outbreak</a>. An infected patient was treated at the <a href="/wiki/Prince_of_Wales_Hospital" title="Prince of Wales Hospital">Prince of Wales Hospital</a>, the teaching hospital for <a href="/wiki/CUHK_Faculty_of_Medicine" title="CUHK Faculty of Medicine">CUHK Faculty of Medicine</a>, turning the hospital into one of the epicenters in Hong Kong.<sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> His group was one of the first to sequence the <a href="/wiki/Severe_acute_respiratory_syndrome_coronavirus_1" class="mw-redirect" title="Severe acute respiratory syndrome coronavirus 1">SARS virus</a><sup id="cite_ref-25" class="reference"><a href="#cite_note-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> and to discover the existence of multiple <a href="/wiki/Virus" title="Virus">viral</a> <a href="/wiki/Strain_(biology)" title="Strain (biology)">strains</a>.<sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup> </p><p>Lo returned to studying detection of cell-free fetal DNA after the SARS outbreak. In 2008, he reported the use of <a href="/wiki/Massive_parallel_sequencing" title="Massive parallel sequencing">next-generation sequencing</a> (NGS), which has a much higher <a href="/wiki/Throughput" class="mw-redirect" title="Throughput">throughput</a> than traditional PCR and was a relatively new technology at the time.<sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> When used to detect <a href="/wiki/Down_syndrome" title="Down syndrome">Down syndrome</a>, which is caused by an extra <a href="/wiki/Chromosome_21" title="Chromosome 21">chromosome 21</a>, this method was later shown to have a 100% <a href="/wiki/Sensitivity_and_specificity" title="Sensitivity and specificity">sensitivity</a> and a nearly 98% <a href="/wiki/Sensitivity_and_specificity" title="Sensitivity and specificity">specificity</a>,<sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup> prompting its introduction into clinics in 2011.<sup id="cite_ref-ajog_7-7" class="reference"><a href="#cite_note-ajog-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>The next year, while watching a <i><a href="/wiki/Harry_Potter_(film_series)" title="Harry Potter (film series)">Harry Potter</a></i> movie in <a href="/wiki/3D_film" title="3D film">3D</a>, the flying "H" reminded him of 2 <a href="/wiki/Homologous_chromosomes" class="mw-redirect" title="Homologous chromosomes">homologous chromosomes</a> and gave him an idea on how to sequence the fetal <a href="/wiki/Genome" title="Genome">genome</a>: to separately sequence the 2 halves of DNA that the foetus inherited from the father and the mother.<sup id="cite_ref-pnas_13-1" class="reference"><a href="#cite_note-pnas-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> For the father's half, they searched for DNA sequences present only in the father but not the mother; for the mother's half, they counted the DNA sequences from the mother to deduce the sequences inherited by the foetus, which would be found in excess in the mother's blood plasma. This discovery created a non-invasive method to detect fetal <a href="/wiki/Mutations" class="mw-redirect" title="Mutations">mutations</a>.<sup id="cite_ref-29" class="reference"><a href="#cite_note-29"><span class="cite-bracket">[</span>29<span class="cite-bracket">]</span></a></sup> In 2013, his group showed that the fetal <a href="/wiki/Epigenome" title="Epigenome">epigenome</a> could also be determined from mother's blood plasma.<sup id="cite_ref-30" class="reference"><a href="#cite_note-30"><span class="cite-bracket">[</span>30<span class="cite-bracket">]</span></a></sup> </p><p>Apart from non-invasive prenatal testing, Lo started investigating cancer <a href="/wiki/Medical_diagnosis" title="Medical diagnosis">diagnosis</a>, profiling and <a href="/wiki/Prognosis" title="Prognosis">prognosis</a> from <a href="/wiki/Circulating_tumor_DNA" title="Circulating tumor DNA">circulating tumor DNA</a> using NGS in 2012, when he reported the genetic profiling of cancer in patients' blood plasma.<sup id="cite_ref-31" class="reference"><a href="#cite_note-31"><span class="cite-bracket">[</span>31<span class="cite-bracket">]</span></a></sup> </p><p>As of October 2021, Lo is an associate editor of <a href="/wiki/Clinical_Chemistry_(journal)" title="Clinical Chemistry (journal)"><i>Clinical Chemistry</i></a>.<sup id="cite_ref-32" class="reference"><a href="#cite_note-32"><span class="cite-bracket">[</span>32<span class="cite-bracket">]</span></a></sup> </p><p>Lo is the co-founder of 2 biotechnology companies, both established in 2014. Using funding from the <a href="/wiki/Venture_capital" title="Venture capital">venture capital</a> firm Decheng Capital, he co-founded Cirina with his longtime CUHK collaborators Rossa Chiu and Allen Chan.<sup id="cite_ref-company_33-0" class="reference"><a href="#cite_note-company-33"><span class="cite-bracket">[</span>33<span class="cite-bracket">]</span></a></sup> The company focuses on cancer detection with circulating tumor DNA.<sup id="cite_ref-34" class="reference"><a href="#cite_note-34"><span class="cite-bracket">[</span>34<span class="cite-bracket">]</span></a></sup> The company was acquired by <a href="/wiki/GRAIL_(company)" class="mw-redirect" title="GRAIL (company)">GRAIL</a> in 2017,<sup id="cite_ref-35" class="reference"><a href="#cite_note-35"><span class="cite-bracket">[</span>35<span class="cite-bracket">]</span></a></sup> which, in turn, was acquired by <a href="/wiki/Illumina,_Inc." title="Illumina, Inc.">Illumina</a> in 2021.<sup id="cite_ref-36" class="reference"><a href="#cite_note-36"><span class="cite-bracket">[</span>36<span class="cite-bracket">]</span></a></sup> The 3 of them also co-founded Xcelom, which commercialised their research in non-invasive prenatal testing.<sup id="cite_ref-company_33-1" class="reference"><a href="#cite_note-company-33"><span class="cite-bracket">[</span>33<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-37" class="reference"><a href="#cite_note-37"><span class="cite-bracket">[</span>37<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-38" class="reference"><a href="#cite_note-38"><span class="cite-bracket">[</span>38<span class="cite-bracket">]</span></a></sup> </p><p>In the <a href="/wiki/2021_Hong_Kong_legislative_election" title="2021 Hong Kong legislative election">2021 Hong Kong legislative election</a>, Lo was a registered elector in the <a href="/wiki/Functional_constituency_(Hong_Kong)" title="Functional constituency (Hong Kong)">functional constituency</a> of <a href="/wiki/Technology_and_Innovation_(constituency)" title="Technology and Innovation (constituency)">Technology and Innovation</a> and the <a href="/wiki/Geographical_constituency" title="Geographical constituency">geographical constituency</a> of <a href="/wiki/Kowloon_West_(2021_constituency)" title="Kowloon West (2021 constituency)">Kowloon West</a>.<sup id="cite_ref-2021lego_39-0" class="reference"><a href="#cite_note-2021lego-39"><span class="cite-bracket">[</span>39<span class="cite-bracket">]</span></a></sup> The State Key Laboratory of Translational Oncology at CUHK, with which he is affiliated, is also a <a href="/wiki/Functional_constituency_(Hong_Kong)#Present" title="Functional constituency (Hong Kong)">corporate elector</a> (an elector that is a <a href="/wiki/Legal_person" title="Legal person">legal entity</a>, as opposed to a <a href="/wiki/Natural_person" title="Natural person">natural person</a>) at the same functional constituency.<sup id="cite_ref-40" class="reference"><a href="#cite_note-40"><span class="cite-bracket">[</span>40<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-41" class="reference"><a href="#cite_note-41"><span class="cite-bracket">[</span>41<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-42" class="reference"><a href="#cite_note-42"><span class="cite-bracket">[</span>42<span class="cite-bracket">]</span></a></sup> As Lo is also a member of the <a href="/wiki/Election_Committee_(Hong_Kong)" title="Election Committee (Hong Kong)">Election Committee of Hong Kong</a>,<sup id="cite_ref-43" class="reference"><a href="#cite_note-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup> making him eligible to vote in the <a href="/wiki/Election_Committee_(constituency)" title="Election Committee (constituency)">Election Committee constituency</a>, he was one of the 41 voters who held 4 votes and whose voting power would be approximately 7,215 times of an ordinary citizen.<sup id="cite_ref-2021lego_39-1" class="reference"><a href="#cite_note-2021lego-39"><span class="cite-bracket">[</span>39<span class="cite-bracket">]</span></a></sup> </p><p>On 22 September 2024, Lo was nominated a candidate to succeed <a href="/wiki/Rocky_Tuan" title="Rocky Tuan">Rocky Tuan</a> as CUHK president and vice-chancellor and was the sole candidate.<sup id="cite_ref-44" class="reference"><a href="#cite_note-44"><span class="cite-bracket">[</span>44<span class="cite-bracket">]</span></a></sup> His nomination was approved unanimously on 27 September 2024 and will assume office on 8 January 2025.<sup id="cite_ref-45" class="reference"><a href="#cite_note-45"><span class="cite-bracket">[</span>45<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Honours_and_awards">Honours and awards</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Dennis_Lo&action=edit&section=3" title="Edit section: Honours and awards"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>2000 - Ten Outstanding Young Person of Hong Kong<sup id="cite_ref-46" class="reference"><a href="#cite_note-46"><span class="cite-bracket">[</span>46<span class="cite-bracket">]</span></a></sup></li> <li>2001 - <a href="/wiki/Ten_Outstanding_Young_Persons_of_the_World" title="Ten Outstanding Young Persons of the World">Ten Outstanding Young Persons of the World</a><sup id="cite_ref-47" class="reference"><a href="#cite_note-47"><span class="cite-bracket">[</span>47<span class="cite-bracket">]</span></a></sup></li> <li>2005 - State Natural Science Award, Second-class, <a href="/wiki/Ministry_of_Science_and_Technology_(China)" title="Ministry of Science and Technology (China)">Ministry of Science and Technology</a>, <a href="/wiki/China" title="China">China</a><sup id="cite_ref-48" class="reference"><a href="#cite_note-48"><span class="cite-bracket">[</span>48<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-49" class="reference"><a href="#cite_note-49"><span class="cite-bracket">[</span>49<span class="cite-bracket">]</span></a></sup></li> <li>2006 - Award for Significant Contributions in Molecular Diagnostics, <a href="/wiki/International_Federation_of_Clinical_Chemistry_and_Laboratory_Medicine" title="International Federation of Clinical Chemistry and Laboratory Medicine">International Federation of Clinical Chemistry and Laboratory Medicine</a><sup id="cite_ref-ifcclm_50-0" class="reference"><a href="#cite_note-ifcclm-50"><span class="cite-bracket">[</span>50<span class="cite-bracket">]</span></a></sup></li> <li>2007 - Award for Outstanding Contribution for a Publication in the International Journal <i><a href="/wiki/Clinical_Chemistry_(journal)" title="Clinical Chemistry (journal)">Clinical Chemistry</a></i>, <a href="/wiki/American_Association_for_Clinical_Chemistry" class="mw-redirect" title="American Association for Clinical Chemistry">American Association for Clinical Chemistry</a><sup id="cite_ref-51" class="reference"><a href="#cite_note-51"><span class="cite-bracket">[</span>51<span class="cite-bracket">]</span></a></sup></li> <li>2011 - <a href="/wiki/Fellow_of_the_Royal_Society" title="Fellow of the Royal Society">Fellow</a> of the <a href="/wiki/Royal_Society" title="Royal Society">Royal Society</a><sup id="cite_ref-52" class="reference"><a href="#cite_note-52"><span class="cite-bracket">[</span>52<span class="cite-bracket">]</span></a></sup></li> <li>2013 - <a href="/wiki/Member_of_the_National_Academy_of_Sciences" title="Member of the National Academy of Sciences">Foreign Associate</a> of the <a href="/wiki/National_Academy_of_Sciences" title="National Academy of Sciences">National Academy of Sciences</a><sup id="cite_ref-pnasmember_53-0" class="reference"><a href="#cite_note-pnasmember-53"><span class="cite-bracket">[</span>53<span class="cite-bracket">]</span></a></sup></li> <li>2013 - Fellow of <a href="/wiki/The_World_Academy_of_Sciences" title="The World Academy of Sciences">The World Academy of Sciences</a><sup id="cite_ref-54" class="reference"><a href="#cite_note-54"><span class="cite-bracket">[</span>54<span class="cite-bracket">]</span></a></sup></li> <li>2014 - <a href="/wiki/King_Faisal_Prize" title="King Faisal Prize">King Faisal Prize</a> in <a href="/wiki/Medicine" title="Medicine">Medicine</a><sup id="cite_ref-kingfaisal_3-3" class="reference"><a href="#cite_note-kingfaisal-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></li> <li>2016 - <a href="/wiki/Future_Science_Prize" title="Future Science Prize">Future Science Prize</a> Life Science Prize<sup id="cite_ref-55" class="reference"><a href="#cite_note-55"><span class="cite-bracket">[</span>55<span class="cite-bracket">]</span></a></sup></li> <li>2020 - Award for Excellence in Molecular Diagnostics, <a href="/wiki/Association_for_Molecular_Pathology" title="Association for Molecular Pathology">Association for Molecular Pathology</a><sup id="cite_ref-56" class="reference"><a href="#cite_note-56"><span class="cite-bracket">[</span>56<span class="cite-bracket">]</span></a></sup></li> <li>2021 - <a href="/wiki/Breakthrough_Prize_in_Life_Sciences" title="Breakthrough Prize in Life Sciences">Breakthrough Prize in Life Sciences</a><sup id="cite_ref-57" class="reference"><a href="#cite_note-57"><span class="cite-bracket">[</span>57<span class="cite-bracket">]</span></a></sup></li> <li>2021 - <a href="/wiki/Royal_Medal" title="Royal Medal">Royal Medal</a><sup id="cite_ref-58" class="reference"><a href="#cite_note-58"><span class="cite-bracket">[</span>58<span class="cite-bracket">]</span></a></sup></li> <li>2022 - <a href="/wiki/Lasker-DeBakey_Clinical_Medical_Research_Award" class="mw-redirect" title="Lasker-DeBakey Clinical Medical Research Award">Lasker-DeBakey Clinical Medical Research Award</a><sup id="cite_ref-59" class="reference"><a href="#cite_note-59"><span class="cite-bracket">[</span>59<span class="cite-bracket">]</span></a></sup></li></ul> <div class="mw-heading mw-heading2"><h2 id="Personal_life">Personal life</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Dennis_Lo&action=edit&section=4" title="Edit section: Personal life"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Lo is married to Alice Siu Ling Wong. They met each other while Lo was pursuing his <a href="/wiki/Doctor_of_Philosophy" title="Doctor of Philosophy">DPhil</a> at the <a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a>, where Wong was completing her DPhil in <a href="/wiki/Semiconductor" title="Semiconductor">semiconductor</a> <a href="/wiki/Physics" title="Physics">physics</a>.<sup id="cite_ref-embryo_4-3" class="reference"><a href="#cite_note-embryo-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> They got married in 1994.<sup id="cite_ref-60" class="reference"><a href="#cite_note-60"><span class="cite-bracket">[</span>60<span class="cite-bracket">]</span></a></sup> </p><p>As of 2016, Wong is an <a href="/wiki/Associate_professor" title="Associate professor">associate professor</a> and the head of the former Division of <a href="/wiki/Mathematics_education" title="Mathematics education">Mathematics</a> and <a href="/wiki/Science_Education" class="mw-redirect" title="Science Education">Science Education</a>, Faculty of Education at the <a href="/wiki/University_of_Hong_Kong" title="University of Hong Kong">University of Hong Kong</a>.<sup id="cite_ref-61" class="reference"><a href="#cite_note-61"><span class="cite-bracket">[</span>61<span class="cite-bracket">]</span></a></sup> She is no longer on the faculty list as of 2021.<sup id="cite_ref-62" class="reference"><a href="#cite_note-62"><span class="cite-bracket">[</span>62<span class="cite-bracket">]</span></a></sup> </p><p>It was reported in 2021 that Lo bought a <a href="/wiki/Apartment" title="Apartment">flat</a> at <a href="/wiki/The_Masterpiece_(Hong_Kong)" title="The Masterpiece (Hong Kong)">The Masterpiece</a> in <a href="/wiki/Tsim_Sha_Tsui" title="Tsim Sha Tsui">Tsim Sha Tsui</a>, <a href="/wiki/Hong_Kong" title="Hong Kong">Hong Kong</a> for <a href="/wiki/Hong_Kong_dollar" title="Hong Kong dollar">HKD</a>$210 million.<sup id="cite_ref-63" class="reference"><a href="#cite_note-63"><span class="cite-bracket">[</span>63<span class="cite-bracket">]</span></a></sup> </p><p>Lo is one of the initiators of the Hong Kong Coalition, co-founded by two former <a href="/wiki/Chief_Executives_of_Hong_Kong" class="mw-redirect" title="Chief Executives of Hong Kong">Chief Executives of Hong Kong</a> <a href="/wiki/Tung_Chee-hwa" title="Tung Chee-hwa">Tung Chee-hwa</a> and <a href="/wiki/Leung_Chun-ying" title="Leung Chun-ying">Leung Chun-ying</a>.<sup id="cite_ref-64" class="reference"><a href="#cite_note-64"><span class="cite-bracket">[</span>64<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Dennis_Lo&action=edit&section=5" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-cuhkmed-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-cuhkmed_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-cuhkmed_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-cuhkmed_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.med.cuhk.edu.hk/staff/professor-lo-yuk-ming-dennis-sbs-jp">"Professor LO Yuk Ming, Dennis, SBS, JP"</a>. <a href="/wiki/CUHK_Faculty_of_Medicine" title="CUHK Faculty of Medicine">CUHK Faculty of Medicine</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20210908151005/https://www.med.cuhk.edu.hk/staff/professor-lo-yuk-ming-dennis-sbs-jp">Archived</a> from the original on 8 September 2021<span class="reference-accessdate">. Retrieved <span class="nowrap">8 September</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Professor+LO+Yuk+Ming%2C+Dennis%2C+SBS%2C+JP&rft.pub=CUHK+Faculty+of+Medicine&rft_id=https%3A%2F%2Fwww.med.cuhk.edu.hk%2Fstaff%2Fprofessor-lo-yuk-ming-dennis-sbs-jp&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-ashk-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-ashk_2-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20210908152322/http://www.ashk.org.hk/en/ourMembers/details/29">"Prof Dennis Y M LO"</a>. Hong Kong Academy of Sciences. 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Retrieved <span class="nowrap">23 September</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Encounters+with+Alumni+from+Greater+China%3A+Dennis+Lo&rft.pub=University+of+Oxford+China+Office&rft_id=http%3A%2F%2Fwww.oxforduchina.org%2Fdennis-lo.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-pnas-13"><span class="mw-cite-backlink">^ <a href="#cite_ref-pnas_13-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pnas_13-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFViegas2013" class="citation journal cs1">Viegas, Jennifer (2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839783">"Profile of Dennis Lo"</a>. <i><a href="/wiki/Proceedings_of_the_National_Academy_of_Sciences" class="mw-redirect" title="Proceedings of the National Academy of Sciences">Proceedings of the National Academy of Sciences</a></i>. <b>110</b> (47): 18742–18743. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2013PNAS..11018742V">2013PNAS..11018742V</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.1317868110">10.1073/pnas.1317868110</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839783">3839783</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24145450">24145450</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences&rft.atitle=Profile+of+Dennis+Lo&rft.volume=110&rft.issue=47&rft.pages=18742-18743&rft.date=2013&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3839783%23id-name%3DPMC&rft_id=info%3Apmid%2F24145450&rft_id=info%3Adoi%2F10.1073%2Fpnas.1317868110&rft_id=info%3Abibcode%2F2013PNAS..11018742V&rft.aulast=Viegas&rft.aufirst=Jennifer&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3839783&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-14">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLoMehalFleming1988" class="citation journal cs1">Lo, Y-M. D.; Mehal, W. Z.; Fleming, K. A. (1988). <a rel="nofollow" class="external text" href="https://www.sciencedirect.com/science/article/abs/pii/S0140673688904874">"False-positive results and the polymerase chain reaction"</a>. <i><a href="/wiki/The_Lancet" title="The Lancet">The Lancet</a></i>. <b>332</b> (8672): 679. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0140-6736%2888%2990487-4">10.1016/S0140-6736(88)90487-4</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2901532">2901532</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:34101803">34101803</a><span class="reference-accessdate">. Retrieved <span class="nowrap">3 October</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Lancet&rft.atitle=False-positive+results+and+the+polymerase+chain+reaction&rft.volume=332&rft.issue=8672&rft.pages=679&rft.date=1988&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A34101803%23id-name%3DS2CID&rft_id=info%3Apmid%2F2901532&rft_id=info%3Adoi%2F10.1016%2FS0140-6736%2888%2990487-4&rft.aulast=Lo&rft.aufirst=Y-M.+D.&rft.au=Mehal%2C+W.+Z.&rft.au=Fleming%2C+K.+A.&rft_id=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fabs%2Fpii%2FS0140673688904874&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-15"><span class="mw-cite-backlink"><b><a href="#cite_ref-15">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLoWainscoatGillmerPatel1989" class="citation journal cs1">Lo, Y-M. D.; Wainscoat, J. S.; Gillmer, M. D. G.; Patel, P.; Sampietro, M.; Fleming, K. A. (1989). <a rel="nofollow" class="external text" href="https://www.sciencedirect.com/science/article/abs/pii/S0140673689919697">"Prenatal sex determination by DNA amplification from maternal peripheral blood"</a>. <i>The Lancet</i>. <b>334</b> (8676): 1363–1365. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fs0140-6736%2889%2991969-7">10.1016/s0140-6736(89)91969-7</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2574306">2574306</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:26365991">26365991</a><span class="reference-accessdate">. Retrieved <span class="nowrap">3 October</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Lancet&rft.atitle=Prenatal+sex+determination+by+DNA+amplification+from+maternal+peripheral+blood&rft.volume=334&rft.issue=8676&rft.pages=1363-1365&rft.date=1989&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A26365991%23id-name%3DS2CID&rft_id=info%3Apmid%2F2574306&rft_id=info%3Adoi%2F10.1016%2Fs0140-6736%2889%2991969-7&rft.aulast=Lo&rft.aufirst=Y-M.+D.&rft.au=Wainscoat%2C+J.+S.&rft.au=Gillmer%2C+M.+D.+G.&rft.au=Patel%2C+P.&rft.au=Sampietro%2C+M.&rft.au=Fleming%2C+K.+A.&rft_id=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fabs%2Fpii%2FS0140673689919697&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-16">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20211006155256/https://scholars.croucher.org.hk/scholars/dennis-lo">"Dennis Lo"</a>. Croucher Foundation. Archived from <a rel="nofollow" class="external text" href="https://scholars.croucher.org.hk/scholars/dennis-lo">the original</a> on 6 October 2021<span class="reference-accessdate">. Retrieved <span class="nowrap">5 October</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Dennis+Lo&rft.pub=Croucher+Foundation&rft_id=https%3A%2F%2Fscholars.croucher.org.hk%2Fscholars%2Fdennis-lo&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-17">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20211006155528/https://cpm.well.ox.ac.uk/person/professor-dennis-lo">"Professor Dennis Lo"</a>. Centre for Personalised Medicine, University of Oxford. Archived from <a rel="nofollow" class="external text" href="https://cpm.well.ox.ac.uk/person/professor-dennis-lo">the original</a> on 6 October 2021<span class="reference-accessdate">. Retrieved <span class="nowrap">5 October</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Professor+Dennis+Lo&rft.pub=Centre+for+Personalised+Medicine%2C+University+of+Oxford&rft_id=https%3A%2F%2Fcpm.well.ox.ac.uk%2Fperson%2Fprofessor-dennis-lo&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-18"><span class="mw-cite-backlink"><b><a href="#cite_ref-18">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLoCorbettaChamberlainRai1997" class="citation journal cs1">Lo, Y. M. Dennis; Corbetta, Noemi; Chamberlain, Paul F.; Rai, Vik; Sargent, Ian L.; Redman, Christopher W. G.; Wainscoat, James S. (1997). <a rel="nofollow" class="external text" href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(97)02174-0/fulltext">"Presence of fetal DNA in maternal plasma and serum"</a>. <i>The Lancet</i>. <b>350</b> (9076): 485–487. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0140-6736%2897%2902174-0">10.1016/S0140-6736(97)02174-0</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9274585">9274585</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:14234791">14234791</a><span class="reference-accessdate">. Retrieved <span class="nowrap">6 October</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Lancet&rft.atitle=Presence+of+fetal+DNA+in+maternal+plasma+and+serum&rft.volume=350&rft.issue=9076&rft.pages=485-487&rft.date=1997&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A14234791%23id-name%3DS2CID&rft_id=info%3Apmid%2F9274585&rft_id=info%3Adoi%2F10.1016%2FS0140-6736%2897%2902174-0&rft.aulast=Lo&rft.aufirst=Y.+M.+Dennis&rft.au=Corbetta%2C+Noemi&rft.au=Chamberlain%2C+Paul+F.&rft.au=Rai%2C+Vik&rft.au=Sargent%2C+Ian+L.&rft.au=Redman%2C+Christopher+W.+G.&rft.au=Wainscoat%2C+James+S.&rft_id=https%3A%2F%2Fwww.thelancet.com%2Fjournals%2Flancet%2Farticle%2FPIIS0140-6736%2897%2902174-0%2Ffulltext&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-guardian-19"><span class="mw-cite-backlink"><b><a href="#cite_ref-guardian_19-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFCorbyn2013" class="citation news cs1">Corbyn, Zoë (1 September 2013). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20201017015808/https://www.theguardian.com/science/2013/sep/01/dennis-lo-prenatal-research-cancer">"Dennis Lo: 'Should parents be told about a disease their child might get?'<span class="cs1-kern-right"></span>"</a>. <i><a href="/wiki/The_Guardian" title="The Guardian">The Guardian</a></i>. Archived from <a rel="nofollow" class="external text" href="https://www.theguardian.com/science/2013/sep/01/dennis-lo-prenatal-research-cancer">the original</a> on 17 October 2020<span class="reference-accessdate">. Retrieved <span class="nowrap">3 October</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Guardian&rft.atitle=Dennis+Lo%3A+%27Should+parents+be+told+about+a+disease+their+child+might+get%3F%27&rft.date=2013-09-01&rft.aulast=Corbyn&rft.aufirst=Zo%C3%AB&rft_id=https%3A%2F%2Fwww.theguardian.com%2Fscience%2F2013%2Fsep%2F01%2Fdennis-lo-prenatal-research-cancer&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-20"><span class="mw-cite-backlink"><b><a href="#cite_ref-20">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLoHjelmFidlerSargent1998" class="citation journal cs1">Lo, Y. M. Dennis; Hjelm, N. Magnus; Fidler, Carrie; Sargent, Ian L.; Murphy, Michael F.; Chamberlain, Paul F.; Priscilla M.K., Poon; Christopher W.G., Redman; Wainscoat, James S. (1998). <a rel="nofollow" class="external text" href="https://doi.org/10.1056%2FNEJM199812103392402">"Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma"</a>. <i><a href="/wiki/The_New_England_Journal_of_Medicine" title="The New England Journal of Medicine">The New England Journal of Medicine</a></i>. <b>339</b> (24): 1734–1738. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1056%2FNEJM199812103392402">10.1056/NEJM199812103392402</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9845707">9845707</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+England+Journal+of+Medicine&rft.atitle=Prenatal+diagnosis+of+fetal+RhD+status+by+molecular+analysis+of+maternal+plasma&rft.volume=339&rft.issue=24&rft.pages=1734-1738&rft.date=1998&rft_id=info%3Adoi%2F10.1056%2FNEJM199812103392402&rft_id=info%3Apmid%2F9845707&rft.aulast=Lo&rft.aufirst=Y.+M.+Dennis&rft.au=Hjelm%2C+N.+Magnus&rft.au=Fidler%2C+Carrie&rft.au=Sargent%2C+Ian+L.&rft.au=Murphy%2C+Michael+F.&rft.au=Chamberlain%2C+Paul+F.&rft.au=Priscilla+M.K.%2C+Poon&rft.au=Christopher+W.G.%2C+Redman&rft.au=Wainscoat%2C+James+S.&rft_id=https%3A%2F%2Fdoi.org%2F10.1056%252FNEJM199812103392402&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-21">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPoonLeungLauLo2000" class="citation journal cs1">Poon, Leo L. M.; Leung, Tse N.; Lau, Tze K.; Lo, Y. M. Dennis (2000). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20211010151142/https://academic.oup.com/clinchem/article/46/11/1832/5641416">"Presence of Fetal RNA in Maternal Plasma"</a>. <i>Clinical Chemistry</i>. <b>46</b> (11): 1832–1834. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fclinchem%2F46.11.1832">10.1093/clinchem/46.11.1832</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11067820">11067820</a>. Archived from <a rel="nofollow" class="external text" href="https://academic.oup.com/clinchem/article/46/11/1832/5641416">the original</a> on 10 October 2021<span class="reference-accessdate">. Retrieved <span class="nowrap">8 October</span> 2021</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clinical+Chemistry&rft.atitle=Presence+of+Fetal+RNA+in+Maternal+Plasma&rft.volume=46&rft.issue=11&rft.pages=1832-1834&rft.date=2000&rft_id=info%3Adoi%2F10.1093%2Fclinchem%2F46.11.1832&rft_id=info%3Apmid%2F11067820&rft.aulast=Poon&rft.aufirst=Leo+L.+M.&rft.au=Leung%2C+Tse+N.&rft.au=Lau%2C+Tze+K.&rft.au=Lo%2C+Y.+M.+Dennis&rft_id=https%3A%2F%2Facademic.oup.com%2Fclinchem%2Farticle%2F46%2F11%2F1832%2F5641416&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-22"><span class="mw-cite-backlink"><b><a href="#cite_ref-22">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPoonLeungLauChow2002" class="citation journal cs1">Poon, Leo L. M.; Leung, Tse N.; Lau, Tze K.; Chow, Katherine C. K.; Lo, Y. M. Dennis (2002). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20211008151406/https://academic.oup.com/clinchem/article/48/1/35/5641529">"Differential DNA Methylation between Fetus and Mother as a Strategy for Detecting Fetal DNA in Maternal Plasma"</a>. <i>Clinical Chemistry</i>. <b>48</b> (1): 35–41. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fclinchem%2F48.1.35">10.1093/clinchem/48.1.35</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11751536">11751536</a>. 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Dennis (2008). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600580">"Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma"</a>. <i>Proceedings of the National Academy of Sciences</i>. <b>105</b> (51): 20458–20463. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2008PNAS..10520458C">2008PNAS..10520458C</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.0810641105">10.1073/pnas.0810641105</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600580">2600580</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19073917">19073917</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences&rft.atitle=Noninvasive+prenatal+diagnosis+of+fetal+chromosomal+aneuploidy+by+massively+parallel+genomic+sequencing+of+DNA+in+maternal+plasma&rft.volume=105&rft.issue=51&rft.pages=20458-20463&rft.date=2008&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2600580%23id-name%3DPMC&rft_id=info%3Apmid%2F19073917&rft_id=info%3Adoi%2F10.1073%2Fpnas.0810641105&rft_id=info%3Abibcode%2F2008PNAS..10520458C&rft.aulast=Chiu&rft.aufirst=Rossa+W.+K.&rft.au=Chan%2C+K.+C.+Allen&rft.au=Gao%2C+Yuan&rft.au=Lau%2C+Virginia+Y.+M.&rft.au=Zheng%2C+Wenli&rft.au=Leung%2C+Tak+Y.&rft.au=Foo%2C+Chris+H.+F.&rft.au=Xie%2C+Bin&rft.au=Tsui%2C+Nancy+B.+Y.&rft.au=Lun%2C+Fiona+M.+F.&rft.au=Zee%2C+Benny+C.+Y.&rft.au=Lau%2C+Tze+K.&rft.au=Cantor%2C+Charles+R.&rft.au=Lo%2C+Y.+M.+Dennis&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2600580&rfr_id=info%3Asid%2Fen.wikipedia.org%3ADennis+Lo" class="Z3988"></span></span> </li> <li id="cite_note-28"><span class="mw-cite-backlink"><b><a href="#cite_ref-28">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChiuAkolekarZhengLeung2011" class="citation journal cs1">Chiu, Rossa W. 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title="Jeremy Baumberg">Jeremy Baumberg</a></li> <li><a href="/wiki/Hagan_Bayley" title="Hagan Bayley">Hagan Bayley</a></li> <li><a href="/wiki/B%C3%A9la_Bollob%C3%A1s" title="Béla Bollobás">Béla Bollobás</a></li> <li><a href="/wiki/Doreen_Cantrell" title="Doreen Cantrell">Doreen Cantrell</a></li> <li><a href="/wiki/Stan_Cowley" title="Stan Cowley">Stan Cowley</a></li> <li><a href="/wiki/Alan_Cowman" title="Alan Cowman">Alan Cowman</a></li> <li><a href="/wiki/Alun_Davies_(biologist)" title="Alun Davies (biologist)">Alun Davies</a></li> <li><a href="/wiki/Nicholas_Franks" title="Nicholas Franks">Nicholas Franks</a></li> <li><a href="/wiki/Ian_Frazer" title="Ian Frazer">Ian Frazer</a></li> <li><a href="https://www.wikidata.org/wiki/Q21166090" class="extiw" title="d:Q21166090">Steven Gamblin</a></li> <li><a href="/wiki/John_Goodby" title="John Goodby">John Goodby</a></li> <li><a href="/wiki/Alan_Grafen" title="Alan Grafen">Alan Grafen</a></li> <li><a href="/wiki/Clare_Grey" title="Clare Grey">Clare Grey</a></li> <li><a href="/wiki/Janet_Hemingway" title="Janet Hemingway">Janet Hemingway</a></li> <li><a href="/wiki/Ian_Horrocks" title="Ian Horrocks">Ian Horrocks</a></li> <li><a href="/wiki/Colin_Humphreys" title="Colin Humphreys">Colin Humphreys</a></li> <li><a href="/wiki/Alex_Kacelnik" title="Alex Kacelnik">Alex Kacelnik</a></li> <li><a href="/wiki/Robert_Kennicutt" title="Robert Kennicutt">Robert Kennicutt</a></li> <li><a href="/wiki/Steffen_Lauritzen" title="Steffen Lauritzen">Steffen Lauritzen</a></li> <li><a class="mw-selflink selflink">Dennis Lo</a></li> <li><i><a href="https://www.wikidata.org/wiki/Q21165125" class="extiw" title="d:Q21165125">Ian Manners</a></i></li> <li><a href="/wiki/David_Manolopoulos" title="David Manolopoulos">David Manolopoulos</a></li> <li><a href="/wiki/Gerhard_Materlik" title="Gerhard Materlik">Gerhard Materlik</a></li> <li><a href="/wiki/James_McKernan" title="James McKernan">James McKernan</a></li> <li><a href="/wiki/Tom_McLeish" title="Tom McLeish">Tom McLeish</a></li> <li><a href="/wiki/David_McMurtry" title="David McMurtry">David McMurtry</a></li> <li><i><a href="https://www.wikidata.org/wiki/Q21166717" class="extiw" title="d:Q21166717">Mervyn Miles</a></i></li> <li><i><a href="https://www.wikidata.org/wiki/Q21165290" class="extiw" title="d:Q21165290">Arthur Milner</a></i></li> <li><a href="/wiki/John_Morton_(cognitive_scientist)" title="John Morton (cognitive scientist)">John Morton</a></li> <li><a href="/wiki/Sean_Munro" title="Sean Munro">Sean Munro</a></li> <li><a href="/wiki/Werner_Nahm" title="Werner Nahm">Werner Nahm</a></li> <li><a href="/wiki/Konstantin_Novoselov" title="Konstantin Novoselov">Konstantin Novoselov</a></li> <li><a href="/wiki/Mark_Pagel" title="Mark Pagel">Mark Pagel</a></li> <li><i><a href="https://www.wikidata.org/wiki/Q21166164" class="extiw" title="d:Q21166164">John Parkes</a></i></li> <li><a href="/wiki/Fiona_Powrie" title="Fiona Powrie">Fiona Powrie</a></li> <li><i><a href="https://www.wikidata.org/wiki/Q1900033" class="extiw" title="d:Q1900033">Mark Randolph</a></i></li> <li><a href="/wiki/Leonard_R._Stephens" title="Leonard R. Stephens">Len Stephens</a></li> <li><a href="/wiki/Patrick_Tam_(biologist)" title="Patrick Tam (biologist)">Patrick Tam</a></li> <li><a href="/wiki/Simon_Tavar%C3%A9" title="Simon Tavaré">Simon Tavaré</a></li> <li><a href="/wiki/Angela_Vincent" title="Angela Vincent">Angela Vincent</a></li> <li><a href="/wiki/Mark_Walport" title="Mark Walport">Mark Walport</a></li> <li><a href="/wiki/Robert_Watson_(scientist)" class="mw-redirect" title="Robert Watson (scientist)">Robert Watson</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Foreign</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/David_Chandler_(chemist)" title="David Chandler (chemist)">David Chandler</a></li> <li><a href="/wiki/Joanne_Chory" title="Joanne Chory">Joanne Chory</a></li> <li><a href="/wiki/Mikhail_Leonidovich_Gromov" class="mw-redirect" title="Mikhail Leonidovich Gromov">Mikhail Gromov</a></li> <li><a href="/wiki/Thomas_J.R._Hughes" title="Thomas J.R. Hughes">Thomas Hughes</a></li> <li><a href="/wiki/Phillip_Allen_Sharp" title="Phillip Allen Sharp">Phillip Allen Sharp</a></li> <li><a href="/wiki/Carla_J._Shatz" title="Carla J. Shatz">Carla J. Shatz</a></li> <li><a href="/wiki/Thomas_A._Steitz" title="Thomas A. Steitz">Thomas A. Steitz</a></li> <li><i><a href="https://www.wikidata.org/wiki/Q21166124" class="extiw" title="d:Q21166124">Edward Stolper</a></i></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox authority-control" aria-labelledby="Authority_control_databases_frameless&#124;text-top&#124;10px&#124;alt=Edit_this_at_Wikidata&#124;link=https&#58;//www.wikidata.org/wiki/Q14915755#identifiers&#124;class=noprint&#124;Edit_this_at_Wikidata" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Authority_control_databases_frameless&#124;text-top&#124;10px&#124;alt=Edit_this_at_Wikidata&#124;link=https&#58;//www.wikidata.org/wiki/Q14915755#identifiers&#124;class=noprint&#124;Edit_this_at_Wikidata" style="font-size:114%;margin:0 4em"><a href="/wiki/Help:Authority_control" title="Help:Authority control">Authority control databases</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q14915755#identifiers" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">International</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><span class="uid"><a rel="nofollow" class="external text" href="https://isni.org/isni/0000000033935372">ISNI</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://viaf.org/viaf/58397756">VIAF</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://id.oclc.org/worldcat/entity/E39PBJpPCbXrM8XpWDYWFxrQbd">WorldCat</a></span></li></ul></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">National</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><span class="uid"><a rel="nofollow" class="external text" href="https://d-nb.info/gnd/1159177015">Germany</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://id.loc.gov/authorities/n98078400">United States</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="http://data.bibliotheken.nl/id/thes/p174343590">Netherlands</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://dbn.bn.org.pl/descriptor-details/9810659914205606">Poland</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="http://olduli.nli.org.il/F/?func=find-b&local_base=NLX10&find_code=UID&request=987007437051905171">Israel</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://opac.kbr.be/LIBRARY/doc/AUTHORITY/14688504">Belgium</a></span></li></ul></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Academics</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><span class="uid"><a rel="nofollow" class="external text" href="https://orcid.org/0000-0001-8746-0293">ORCID</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://www.researcherid.com/rid/D-4468-2011">ResearcherID</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://www.scopus.com/authid/detail.uri?authorId=7102171658">Scopus</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://publons.com/author/2795262/">Publons</a></span></li></ul></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><span class="uid"><a rel="nofollow" class="external text" href="https://www.idref.fr/05970649X">IdRef</a></span></li></ul></div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; 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