Psychiatrist.com: JCP, PCC, and The CME Institute

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<input type="text" class="form-control" placeholder="Enter Title, Author or Keyword" name="title" aria-label="Go to page" tabindex="1"> </div> </form>   </div> </div> </nav> </div> </div> </div>    </header>   <section class="main-content" role="main"> <div class="container"> <div class="row">  <div class="left-contentbox col-12 col-md-7 col-lg-8"> <div class="c-blog-list"> <div class="row"> <div class="col-12 c-blog-list-single"> <div class="c-blog-list-post"> <div class="post-cat-title"> <h7><a href="#" aria-label="Go to page">JCP | ACADEMIC HIGHLIGHTS</a></h7> </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12 featured-hero col-lg-7"> <h2><a href="https://www.psychiatrist.com/jcp/difficult-to-treat-depression-focus-on-approach-algorithms-access/" aria-label="Go to page">Difficult to Treat Depression: Focus on Approach, Algorithms, and Access</a></h2> <p class="excerpt">The Southwest Forum on Difficult to Treat Depression brought together 11 experts to discuss aspects of managing difficult-to-treat depression. This article presents highlights from the forum, covering such topics as barriers to equitable care, evidence-based algorithms, novel treatment mechanisms, digital therapies, late-life depression, emerging biomarkers, and personalized treatment.</p> <h3><em>J Clin Psychiatry 2024;85(4):psprmdd2408ah</em></h3> </div> <div class="col-12 col-lg-5"> <a href="https://www.psychiatrist.com/jcp/difficult-to-treat-depression-focus-on-approach-algorithms-access/" aria-label="Go to page"> <img style="margin-bottom:20px" alt="Difficult to Treat Depression: Focus on Approach, Algorithms, and Access" data-src="https://www.psychiatrist.com/wp-content/uploads/2024/11/JCP_Difficult-to-Treat-Depression.jpg" class="align-right lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img style="margin-bottom:20px" src="https://www.psychiatrist.com/wp-content/uploads/2024/11/JCP_Difficult-to-Treat-Depression.jpg" alt="Difficult to Treat Depression: Focus on Approach, Algorithms, and Access" class="align-right" /></noscript> </a> </div> </div> </div> <div class="c-blog-list-post-info"> <h9>  Jordan F. Karp and others  </h9> </div> </div> </div> <div class="col-12 col-md-6 c-blog-list-single">  <div class="c-blog-list-post red"> <div class="post-cat-title"> <h7><a href="#" aria-label="Go to page">JCP | ACADEMIC HIGHLIGHTS</a></h7> </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12"> <a href="https://www.psychiatrist.com/jcp/dysregulation-of-noradrenergic-activity/" aria-label="Go to page"> <img alt="Dysregulation of Noradrenergic Activity" data-src="https://www.psychiatrist.com/wp-content/uploads/2022/11/1200x800_P-LUN-ARO-2417.jpg" class="align-center lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://www.psychiatrist.com/wp-content/uploads/2022/11/1200x800_P-LUN-ARO-2417.jpg" alt="Dysregulation of Noradrenergic Activity" class="align-center" /></noscript> </a> <br> <h2><a href="https://www.psychiatrist.com/jcp/dysregulation-of-noradrenergic-activity/" aria-label="Go to page">Dysregulation of Noradrenergic Activity</a></h2> <p class="excerpt">Dysregulation of noradrenergic activity plays a key role in symptom presentation in major depressive disorder, schizophrenia, Alzheimer’s agitation, and PTSD. This article provides an expert panel’s consensus regarding the mechanisms behind noradrenergic dysfunction, its impact within these disease states, and the role of norepinephrine as a common treatment target.</p> <h3><em>J Clin Psychiatry 2024;85(4):plunaro2417ah</em></h3> </div> </div> </div> <div class="c-blog-list-post-info"> <h9>  Rakesh Jain and others  </h9> </div> </div>  </div> <div class="col-12 col-md-6 c-blog-list-single">  <div class="c-blog-list-post red"> <div class="post-cat-title"> <h7><a href="#" aria-label="Go to page">JCP | INSIGHTS</a></h7> </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12"> <a href="https://www.psychiatrist.com/jcp/muscarinic-receptor-modulators-clinical-care-patients-schizophrenia/" aria-label="Go to page"> <img alt="What is the Place of Muscarinic Receptor Modulators in the Clinical Care of Patients With Schizophrenia?" data-src="https://www.psychiatrist.com/wp-content/uploads/2024/11/P-KAR-SCZ-2435_Correll_E03_V1.png" class="align-center lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://www.psychiatrist.com/wp-content/uploads/2024/11/P-KAR-SCZ-2435_Correll_E03_V1.png" alt="What is the Place of Muscarinic Receptor Modulators in the Clinical Care of Patients With Schizophrenia?" class="align-center" /></noscript> </a> <br> <h2><a href="https://www.psychiatrist.com/jcp/muscarinic-receptor-modulators-clinical-care-patients-schizophrenia/" aria-label="Go to page">What is the Place of Muscarinic Receptor Modulators in the Clinical Care of Patients With Schizophrenia?</a></h2> <p class="excerpt">This video features Dr. Christoph Correll discussing the clinical application of muscarinic receptor modulators in schizophrenia treatment. He explores their unique mechanism of action, compares them to traditional antipsychotics, and highlights their reduced side effect profile. The discussion also covers the potential for combination therapies, switching strategies, and future applications of this groundbreaking class of medications in psychiatric care.</p> </div> </div> </div> <div class="c-blog-list-post-info"> <h9>  Christoph Correll  </h9> </div> </div>  </div> <div class="col-12 col-md-6 c-blog-list-single">  <div class="c-blog-list-post red"> <div class="post-cat-title"> <h7><a href="#" aria-label="Go to page">JCP | INSIGHTS</a></h7> </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12"> <a href="https://www.psychiatrist.com/jcp/anticholinergic-burden-in-schizophrenia/" aria-label="Go to page"> <img alt="Anticholinergic Burden in Schizophrenia" data-src="https://www.psychiatrist.com/wp-content/uploads/2024/10/P-KAR-SCZ-2435_Harvey_E01_Thumb_01.png" class="align-center lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://www.psychiatrist.com/wp-content/uploads/2024/10/P-KAR-SCZ-2435_Harvey_E01_Thumb_01.png" alt="Anticholinergic Burden in Schizophrenia" class="align-center" /></noscript> </a> <br> <h2><a href="https://www.psychiatrist.com/jcp/anticholinergic-burden-in-schizophrenia/" aria-label="Go to page">Anticholinergic Burden in Schizophrenia</a></h2> <p class="excerpt">In this video, Philip D. Harvey, PhD discusses anticholinergic burden in schizophrenia, highlighting its cognitive impact, particularly memory impairments linked to M1 receptor blockade. He underscores the heightened dementia risk from anticholinergic use, especially in older patients, and emphasizes the clinical importance of managing anticholinergic burden due to its iatrogenic effects on cognition, independent of genetic dementia risk factors.</p> </div> </div> </div> <div class="c-blog-list-post-info"> <h9>  Philip D. Harvey  </h9> </div> </div>  </div> <div class="col-12 col-md-6 c-blog-list-single">  <div class="c-blog-list-post red"> <div class="post-cat-title"> <h7><a href="#" aria-label="Go to page">JCP | INSIGHTS</a></h7> </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12"> <a href="https://www.psychiatrist.com/jcp/prevalence-determinants-everyday-disability-in-schizophrenia/" aria-label="Go to page"> <img alt="Prevalence and Determinants of Everyday Disability in Schizophrenia" data-src="https://www.psychiatrist.com/wp-content/uploads/2024/10/P-KAR-SCZ-2435_Harvey_E03_Thumb_01.png" class="align-center lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://www.psychiatrist.com/wp-content/uploads/2024/10/P-KAR-SCZ-2435_Harvey_E03_Thumb_01.png" alt="Prevalence and Determinants of Everyday Disability in Schizophrenia" class="align-center" /></noscript> </a> <br> <h2><a href="https://www.psychiatrist.com/jcp/prevalence-determinants-everyday-disability-in-schizophrenia/" aria-label="Go to page">Prevalence and Determinants of Everyday Disability in Schizophrenia</a></h2> <p class="excerpt">In this video, Philip D. Harvey, PhD discusses the multifaceted nature of disability in schizophrenia, highlighting the impact of cognitive impairments, functional capacity, and negative symptoms on everyday outcomes like independent living and social engagement. He explains that while cognition affects vocational and independent living outcomes, social outcomes are also linked to social motivation and competence. He underscores that targeting multiple factors will be crucial to effectively reduce disability in severe mental illness.</p> </div> </div> </div> <div class="c-blog-list-post-info"> <h9>  Philip D. Harvey  </h9> </div> </div>  </div> <div class="col-12 col-md-6 c-blog-list-single">  <div class="c-blog-list-post red"> <div class="post-cat-title"> <h7><a href="#" aria-label="Go to page">JCP | ORIGINAL RESEARCH</a></h7> </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12"> <a href="https://www.psychiatrist.com/jcp/rates-major-depressive-bipolar-disorder-black-white-postpartum-women/" aria-label="Go to page"> <img alt="MDD and Bipolar Disorder in Black and White Postpartum Women" data-src="https://www.psychiatrist.com/wp-content/uploads/2024/11/JCP_MDD-and-BPD-Rates.jpg" class="align-center lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://www.psychiatrist.com/wp-content/uploads/2024/11/JCP_MDD-and-BPD-Rates.jpg" alt="MDD and Bipolar Disorder in Black and White Postpartum Women" class="align-center" /></noscript> </a> <br> <h2><a href="https://www.psychiatrist.com/jcp/rates-major-depressive-bipolar-disorder-black-white-postpartum-women/" aria-label="Go to page">MDD and Bipolar Disorder in Black and White Postpartum Women</a></h2> <p class="excerpt">No significant difference was observed in the rate of postpartum MDD in Black (40%) versus white (35%) women. However, bipolar disorder significantly differed between Black (19.2%) and white (11.5%) women.</p> <h3><em>J Clin Psychiatry. 2024;85(4):23m15023</em></h3> </div> </div> </div> <div class="c-blog-list-post-info"> <h9>  Taylor N. Burchfield and others  </h9> </div> </div>  </div> <div class="col-12 col-md-6 c-blog-list-single">  <div class="c-blog-list-post blue"> <div class="post-cat-title"> <h7><a href="#" aria-label="Go to page">PCC | CASE REPORT</a></h7> </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12"> <a href="https://www.psychiatrist.com/pcc/panic-attacks-presentation-covid-19/" aria-label="Go to page"> <img alt="Panic Attacks in COVID-19" data-src="https://www.psychiatrist.com/wp-content/uploads/2024/11/PCC_Panic-Attacks-COVID.jpg" class="align-center lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://www.psychiatrist.com/wp-content/uploads/2024/11/PCC_Panic-Attacks-COVID.jpg" alt="Panic Attacks in COVID-19" class="align-center" /></noscript> </a> <br> <h2><a href="https://www.psychiatrist.com/pcc/panic-attacks-presentation-covid-19/" aria-label="Go to page">Panic Attacks in COVID-19</a></h2> <p class="excerpt">This case describes panic attacks that occurred repeatedly as part of the constellation of presenting symptomatology during 2 separate COVID-19 infections.</p> <h3><em>Prim Care Companion CNS Disord 2024;26(6):24cr03714</em></h3> </div> </div> </div> <div class="c-blog-list-post-info"> <h9>  Tej Joshi and others  </h9> </div> </div>  </div> </div> <div class="row justify-content-center"> <div class="textwidget"><div class="widget-area"> <div class="g-ad-apart boder-x"><div class="gad-square ad_mid_content_1"> <div id="ad-Ros_Content"><p class="advertisement">Advertisement</p><script> googletag.cmd.push(function() { googletag.display('ad-Ros_Content'); }); </script></div> </div></div></div></div> </div>  <h6>RECENT CME ACTIVITIES</h6>  <div class="row"> <div class="col-12 col-md-6 c-blog-list-single">  <div class="c-blog-list-post "> <div class="post-cat-title"> <span class="box-icon"></span> <h7 class="credit-score"> CREDIT</h7> <h7><a href="" target="_blank"></a></h7> </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12 "> <h2><a href="" target="_blank" aria-label="Go to page"></a></h2> <p class="excerpt"></p> </div> </div> </div> <div class="c-blog-list-post-info">  <span class="duration">EXP. </span> </div> </div>  </div> </div> <div class="d-g-ad for_desktop"> <div class="textwidget"><div class="widget-area"> <div class="g-ad-apart boder-x"><div class="gad-horiz"> <div id="ad-Ros_Mid_Content_2"><p class="advertisement">Advertisement</p><script> googletag.cmd.push(function() { googletag.display('ad-Ros_Mid_Content_2'); }); </script></div> </div></div></div></div> </div>   <div class="r-sidebar col-12 col-md-5 col-lg-4 for_mobile" data-sidebar="home"> <div class="textwidget"><div class="widget-area"> <div class="g-ad-apart boder-x"><div class="gad-square ad_mid_content_2"> <div id="ad-Ros_Mid_Content_1"><p class="advertisement">Advertisement</p><script> googletag.cmd.push(function() { googletag.display('ad-Ros_Mid_Content_1'); }); </script></div> </div></div></div></div> <div class="widget-area"> <div class="m-popular"> <h8>MOST POPULAR</h8>  <div class="row" data-id="57896"> <div class="col-12 c-blog-list-single">  <div class="c-blog-list-post blue"> <div class="post-cat-title"> <span class="box-icon"></span> <h7><span style="cursor: pointer;" >CASE REPORT</span></h7>  </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12"> <h2><a href="https://www.psychiatrist.com/pcc/recurrent-catatonia-radiation-hypothyroidism/" aria-label="Go to page">Recurrent Catatonia Following Hypothyroidism</a></h2> <h3>The authors present the case of a 41-year-old woman with schizophrenia, in whom hypothyroi...</h3> <h3><em>Prim Care Companion CNS Disord 2024;26(6):24cr03800</em></h3> </div> </div> </div> <div class="c-blog-list-post-info"> <h9> Vincent Zhang and others</h9> </div> </div>  </div> </div> <div class="row" data-id="57750"> <div class="col-12 c-blog-list-single">  <div class="c-blog-list-post red"> <div class="post-cat-title"> <span class="box-icon"></span> <h7><span style="cursor: pointer;" >ACADEMIC HIGHLIGHTS</span></h7>  </div> <div class="c-blog-list-post-cont" role="contentinfo"> <div class="row align-item-center"> <div class="col-12"> <h2><a href="https://www.psychiatrist.com/jcp/difficult-to-treat-depression-focus-on-approach-algorithms-access/" aria-label="Go to page">Difficult to Treat Depression: Focus on Approach, Algorithms, and Access</a></h2> <h3>The Southwest Forum on Difficult to Treat Depression brought together 11 experts to discus...</h3> <h3><em>J Clin Psychiatry 2024;85(4):psprmdd2408ah</em></h3> </div> </div> </div> <div class="c-blog-list-post-info"> <h9> Jordan F. 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Editor: Dr Andrade’s analysis of the Bacloville trial in a recent Clinical and Practical Psychopharmacology column, in which he concluded that “individualized treatment with high-dose baclofen (30-300 mg/d) may be a useful second-line approach in heavy drinkers” and that “baclofen may be particularly useful in patients with liver disease,” deserves comment.1 First, Andrade failed to recall that the first pivotal trial of baclofen, ALPADIR (NCT01738282; 320 patients, as with Bacloville), was negative (see Braillon et al2). Second, Dr Andrade should have warned readers that Bacloville’s results are most questionable, lacking robustness. Although he cited us,3 he overlooked the evidence we provided indicating that the Bacloville article4 was published without acknowledging major changes to the initial protocol, affecting the primary outcome. Coincidentally (although as skeptics, we do not believe in coincidence), the initial statistical team was changed when data were sold to the French pharmaceutical company applying for the marketing authorization in France. As Ronald H. Coase warned, “If you torture the data long enough, it will confess.” </div> </div> </div> </div>   <div class="modal fade" id="related_articles_modal" tabindex="-1" role="dialog" aria-labelledby="exampleModalCenterTitle" aria-hidden="true"> <div class="modal-dialog modal-dialog-centered" role="document"> <div class="modal-content"> <div class="modal-header"> <h5 class="modal-title" id="exampleModalLongTitle">Related Articles</h5> <button type="button" class="close" data-dismiss="modal" aria-label="Close"> <span aria-hidden="true">×</span> </button> </div> <div class="modal-body"> <div id="trendmd-suggestions"></div> </div> <div class="modal-footer"> <button type="button" class="btn btn-secondary" data-dismiss="modal">Close</button> </div> </div> </div> </div> <div class="modal fade" id="toc_articles_modal" tabindex="-1" role="dialog" aria-labelledby="exampleModalCenterTitle" aria-hidden="true"> <div class="modal-dialog modal-dialog-centered" role="document"> <div class="modal-content"> <div class="modal-header"> <h5 class="modal-title" id="exampleModalLongTitle">Table Of Contents</h5> <button type="button" class="close" data-dismiss="modal" aria-label="Close"> <span aria-hidden="true">×</span> </button> </div> <div class="modal-body"> <div id="sections"></div> </div> <div class="modal-footer"> <button type="button" class="btn btn-secondary" data-dismiss="modal">Close</button> </div> </div> </div> </div> <div class="wordpress_loader" id="JCP_loader" style="display:none;"></div> <script type="text/javascript"> (function () { var c = document.body.className; 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