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class="visually-hidden">Search</label> <input title="Enter the terms you wish to search for." data-drupal-selector="edit-keys" type="search" id="edit-keys--2" name="keys" value="" size="15" maxlength="128" class="form-search" placeholder="What are you looking for?"/> </div> <div data-drupal-selector="edit-actions" class="form-actions js-form-wrapper form-wrapper" id="edit-actions--2"><input data-drupal-selector="edit-submit" type="submit" id="edit-submit--2" value="Search" class="button js-form-submit form-submit" /> </div> </form> </div> </div> </div> </div> </div> <div id="content-wrapper"> <div id="header-separator"> </div> <div id="content"> <div class="container clearfix"> <div class="grid"> <div id="block-nc3rs-breadcrumbs" class="block block-system block-system-breadcrumb-block"> <div class="content"> <div class="breadcrumb"> <h2 class="visually-hidden">Breadcrumb</h2> <a href="/" class="breadcrumblink first">Home</a> <span class="breadcrumb-separator sm-fonticons18"></span> <a href="/guide" class="breadcrumblink">User support</a> </div> </div> </div> </div> </div> <div id="content-inside" class="container clearfix"> <div id="main" class="grid_8 narrow" tabindex="-1"> <div id="highlighted"> <div data-drupal-messages-fallback class="hidden"></div> </div> <!-- Tabs --> <!-- Main content --> <div id="block-nc3rs-page-title" class="block block-core block-page-title-block"> <div class="content"> <h1> <span>Examples and Templates</span> </h1> </div> </div> <div id="block-nc3rs-system-main" class="block block-system block-system-main-block"> <div class="content"> <div data-history-node-id="45" about="/guide-examples"> <div class="content clearfix" > <div><p>**Template and example information is now available once you have logged in to the EDA app, on a dedicated Templates page. This user guide page will be retired at a future date.**</p> <p>These examples are provided to illustrate how different features of an experimental design can be represented as EDA diagrams. Only the information included in the text descriptions is included on the diagrams as the examples are not meant to represent a complete experimental plan but to illustrate specific points.</p> <p>Each example is associated with a template, from which most experiment-specific information has been removed. The purpose of the templates is to provide diagrams that users can use as a starting point. Users should not be tempted to match their experiments to the examples and templates, and are encouraged to think constructively about the best approach to their experimental question, using the advice provided in the EDA web application and on this website. </p> <p>Features included in each example:</p> <h3><a href="/guide-example1">Example 1 - Effect of drug A on plasma glucose level</a></h3> <p>Two-group comparison | Animal as experimental unit | Complete randomisation</p> <h3><a href="/guide-example2">Example 2 - Effect of a 5-HT<sub>4</sub> partial agonist on attentional deficit in rats</a></h3> <p>Animals used as their own control | Crossover | Blocking factor | Order of treatments | Test period</p> <h3><a href="/guide-example3">Example 3 - Effect of genotype on plasma glucose </a></h3> <p>Multiple animal characteristics | No randomisation | Data transformation | Multiple time points | Multiple outcome measures | Sex and genotype as factors of interest | Two-way ANOVA with interaction</p> <h3><a href="/guide-example4">Example 4 - Effect of exercise on neuronal density</a></h3> <p>Randomisation with sex as a factor of interest | Nuisance variable | Nested variable | Two-way ANOVA with interaction | Data averaged per animal | Multiple animal characteristics</p> <h3 style="line-height: 20.0063056945801px;"><a href="/guide-example5">Example 5 - Effect of THC on body temperature</a></h3> <p>Three-group comparison | Blocking factor | Block randomisation | One-way ANOVA | Data transformation</p> <p style="text-align: right;"> </p> </div> </div> <div class="clearfix"> </div> </div> </div> </div> <div id="sidebar-first" class="grid_4"> </div> <div class="publishedInformation"> <div class="publishedDate">First published 18 June 2014</div> <div class="updatedDate">Last updated 27 September 2023</div> </div> </div> </div> </div> </div> <div id="footer"> <div id="footer-inside" class="container clearfix"> <div class="footer-area grid_4"> </div> <div 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