CINXE.COM

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style="height:735px;"> </div>  <div class="bg blue visible-lg-*" style="height:1140px;"> </div>  <div class="bg white visible-lg-*" style="height:735px;"> </div>  <div class="bg pink visible-lg-*" style="height:1140px;"> </div>  <div class="bg white visible-lg-*" style="height:1035px;"> </div>  <div class="bg blue visible-lg-*" style="height:1140px;"> </div>  <div class="bg white visible-lg-*" style="height:735px;"> </div> </div> </div> <main class="page" id="hcp_about"> <div class="new-hero"> <div class="container"> <div class="row"> <div class="col-md-12 col-sm-12"> <p>AHP Management<br /> and Treatment Options</p> </div> </div> </div> </div>  <header> <h1>FIND AN APPROACH<br /> FOR YOUR PATIENTS</h1> </header> <div class="striped"> <section id="comparison"> <div class="container"> <div class="content-wrapper" style="padding-top:0;"> <div class="row"> <div class="col-md-10 col-md-offset-1 col-sm-12"> <div class="tbl"> <div class="tbl-head"> <h3>AHP MANAGEMENT AND TREATMENT OPTIONS</h3> </div> <div class="tbl-cont"> <p><strong>Glucose and carbohydrate loading</strong><sup>1,2</sup></p> <p>Used for the treatment of attacks</p>   <p><strong>Hemin</strong><sup>3,4</sup></p> <p>Used for the treatment of attacks</p>   <p><strong>Hormone therapy (GnRH analogs)</strong><sup>1,5</sup></p> <p>Used for patients experiencing AHP attacks related to their menstrual cycles</p>   <p><strong>Liver transplantation</strong><sup>3,5</sup></p> <p>Used rarely in severe cases where other approaches have been unsuccessful</p>   <p><strong>Medications to treat pain</strong><sup>1,6</sup></p> <p>Used to manage painful AHP symptoms</p>   <p><strong>Medications to treat symptoms</strong><sup>3</sup></p> <p>Used to treat and reduce AHP symptoms like nausea, constipation, tachycardia (fast heartbeat), and seizures</p>   <p><strong>RNA interference therapy</strong><sup>5</sup></p> <p>Used to help reduce the frequency of AHP attacks</p>   <p><strong>Trigger avoidance</strong><sup>5</sup></p> <p>Use caution with certain foods, drugs, and behaviors that may increase the risk of AHP attacks</p> </div> </div> </div> </div> <div class="row cta"> <div class="col-md-10 col-md-offset-1 col-sm-12"> <div class="porphyriaCTA mb-20"> <div class="text-center"> <div class="cell"> <a class="do-not-open-twice" data-anchor="module3" href="https://www.givlaarihcp.com" style="text-decoration:none; font-weight:400;" target="_blank"><p>Discover an FDA-approved<br class="nobrmobile" /> Treatment for Adults With AHP</p></a> </div> </div> </div> </div> </div> <div class="row"> <div class="col-xs-12 col-sm-12 col-md-12"><a class="warnOnLeaveModalAlnylamTrigger connect-link" href="https://alnylamconnect.com/dsa?disease=Acute%20hepatic%20porphyria">Connect With an Alnylam Rep</a></div> </div> </div> </div> </section> </div> <a id="signUpNow" name="signUpNow"></a> <div class="form"> <div class="container"> <div class="content-wrapper mb-60"> <div class="row"> <div class="col-xs-12 col-sm-12 col-md-12 col-lg-10 col-lg-push-1"> <div id="append-hcp-signup"> </div> </div> </div> </div> </div> </div>  <div class="legal"> <div class="container"> <div class="content-wrapper"> <div class="row"> <div class="col-xs-12 col-sm-12 col-md-12 col-lg-10 col-lg-push-1"> <p><small><strong>References: 1.</strong> Wang B, Rudnick S, Cengia B, Bonkovsky HL. <em>Hepatol Commun</em>. 2019;3(2):193-206. <strong>2.</strong> Pischik E, Kauppinen R. <em>Appl Clin Genet</em>. 2015;8:201-214. <strong>3.</strong> Anderson KE, Bloomer JR, Bonkovsky HL, et al. <em>Ann lntern Med</em>. 2005;142(6):439-450. <strong>4.</strong> Panhematin [prescribing information]. Lebanon, NJ: Recordati Rare Diseases Inc; 2017. <strong>5.</strong> Balwani M, Wang B, Anderson KE, et al; for the Porphyrias Consortium of Rare Diseases Clinical Research Network. <em>Hepatology</em>. 2017;66(4):1314-1322. <strong>6.</strong> Puy H, Gouya L, Deybach JC. <em>Lancet</em>. 2010; 375:924-937.</small></p> </div> </div> </div> </div> </div> </main> </div> </article> </div> <div class="views-element-container" id="block-views-block-view-footer-custom-block-block-view-footer"> <div><div class="js-view-dom-id-4366d28846f39b5a5638f92a02c460c39c0c70ef914d638a08f8b8833e6a94f0"> </div> </div> </div> <section id="signUp" class="hcp-signup"> <div class="container"> <div id="hcp_signup_form"> <div class="row"> <h1>Sign Up To Receive Updates</h1> <p><em>All fields are required.</em></p> </div> <div id="errorMessages"> </div> <form class="form" id="signupForm" method="post" novalidate=""> <input type="text" class="hpot" name="hcap" value=""> <div class="row"> <div class="col-sm-6 col-md-6"><label for="tbFirstName">First Name</label> <input class="form-control" id="tbFirstName" maxlength="50" name="firstName" required="" type="text" /></div> <div class="col-sm-6 col-md-6"><label for="tbLastName">Last Name</label> <input class="form-control" id="tbLastName" maxlength="50" name="lastName" required="" type="text" /></div> </div> <div class="row"> <div class="col-sm-6 col-md-6"><label for="tbEmail">Email Address</label> <input class="form-control" email="" id="tbEmail" maxlength="254" name="email" required="" type="email" /></div> <div class="col-sm-6 col-md-6"><label for="tbZipCode">ZIP Code</label> <input class="form-control" id="tbZipCode" maxlength="10" minlength="5" name="postalCode" number="" required="" type="text" /></div> </div> <div class="row"> <div class="col-sm-6 col-md-6"><label for="ddlProfessional">Professional Designation</label> <select class="form-control" id="ddlProfessional" name="designation" required="" selected="selected"><option value="0">SELECT</option> <option value="1">Licensed Practical Nurse</option> <option value="2">Medical Assistant</option> <option value="3">Medical Doctor</option> <option value="4">Medical Professional</option> <option value="5">Nurse Practitioner</option> <option value="6">Office Staff</option> <option value="7">Other</option> <option value="8">Pharmacist</option> <option value="9">Pharmacist Technician</option> <option value="10">Physician's Assistant</option> <option value="11">Registered Nurse</option> </select> </div> <div class="col-sm-6 col-md-6"><label for="ddlMedical">Medical Specialization</label> <select class="form-control" id="ddlMedical" name="specialization" required="" selected="selected"><option value="0">SELECT</option> <option value="1">Cardiology</option> <option value="2">Dermatology</option> <option value="3">Emergency Medicine</option> <option value="4">Family Practice</option> <option value="5">Gastroenterology</option> <option value="6">Genetics</option> <option value="7">Hematology</option> <option value="8">Hepatology</option> <option value="9">Internal Medicine</option> <option value="10">Medical Professional</option> <option value="11">Neurology</option> <option value="12">OB-GYN</option> <option value="13">Oncology</option> <option value="14">Ophthalmology</option> <option value="15">Other</option> <option value="16">Pathology</option> <option value="17">Pediatrics</option> <option value="18">Primary Care</option> </select></div> </div> <div class="row"> <div class="col-sm-12 col-md-11 consent"><label class="control control-checkbox">By submitting this form, I certify that I am a healthcare professional, and I am a resident of the United States. 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