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name="abstracts" type="radio" value="hide"> <label for="abstracts-1">Hide abstracts</label></li></ul> </div> <div class="box field is-grouped is-grouped-multiline level-item"> <div class="control"> <span class="select is-small"> <select id="size" name="size"><option value="25">25</option><option selected value="50">50</option><option value="100">100</option><option value="200">200</option></select> </span> <label for="size">results per page</label>. </div> <div class="control"> <label for="order">Sort results by</label> <span class="select is-small"> <select id="order" name="order"><option selected value="-announced_date_first">Announcement date (newest first)</option><option value="announced_date_first">Announcement date (oldest first)</option><option value="-submitted_date">Submission date (newest first)</option><option value="submitted_date">Submission date (oldest first)</option><option value="">Relevance</option></select> </span> </div> <div class="control"> <button class="button is-small is-link">Go</button> </div> </div> </form> </div> </div> <ol class="breathe-horizontal" start="1"> <li class="arxiv-result"> <div class="is-marginless"> <p class="list-title is-inline-block"><a href="https://arxiv.org/abs/2411.14107">arXiv:2411.14107</a> <span> [<a href="https://arxiv.org/pdf/2411.14107">pdf</a>, <a href="https://arxiv.org/format/2411.14107">other</a>] </span> </p> <div class="tags is-inline-block"> <span class="tag is-small is-link tooltip is-tooltip-top" data-tooltip="Neurons and Cognition">q-bio.NC</span> </div> </div> <p class="title is-5 mathjax"> Inward rectifier potassium channels interact with calcium channels to promote robust and physiological bistability </p> <p class="authors"> <span class="search-hit">Authors:</span> <a href="/search/q-bio?searchtype=author&query=De+Worm%2C+A">Ana毛lle De Worm</a>, <a href="/search/q-bio?searchtype=author&query=Drion%2C+G">Guillaume Drion</a>, <a href="/search/q-bio?searchtype=author&query=Sacr%C3%A9%2C+P">Pierre Sacr茅</a> </p> <p class="abstract mathjax"> <span class="has-text-black-bis has-text-weight-semibold">Abstract</span>: <span class="abstract-short has-text-grey-dark mathjax" id="2411.14107v1-abstract-short" style="display: inline;"> In the dorsal horn, projection neurons play a significant role in pain processing by transmitting sensory stimuli to supraspinal centers during nociception. Following exposure to intense noxious stimuli, a sensitization process occurs to adapt the dorsal horn functional state. Notably, projection neurons can display a switch in firing pattern from tonic firing to plateau potentials with sustained… <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('2411.14107v1-abstract-full').style.display = 'inline'; document.getElementById('2411.14107v1-abstract-short').style.display = 'none';">▽ More</a> </span> <span class="abstract-full has-text-grey-dark mathjax" id="2411.14107v1-abstract-full" style="display: none;"> In the dorsal horn, projection neurons play a significant role in pain processing by transmitting sensory stimuli to supraspinal centers during nociception. Following exposure to intense noxious stimuli, a sensitization process occurs to adapt the dorsal horn functional state. Notably, projection neurons can display a switch in firing pattern from tonic firing to plateau potentials with sustained afterdischarges. For afterdischarges to manifest after this switch, the neuron must develop bistability, which characterizes the ability to show resting or spiking at the same input current depending on the context. In numerous instances, neuronal bistability arises through voltage-gated calcium channels. However, computational studies have demonstrated a trade-off between bistability and the plausibility of its resting states if calcium channels are counterbalanced with voltage-gated potassium channels. Current knowledge leaves a gap in understanding the underlying mechanisms by which robust bistability, plateau potentials, and sustained afterdischarges emerge in neurons via calcium channels. In this study, we used a conductance-based model to explore the mechanisms by which L-type calcium (CaL) channels can achieve bistability when combined with either M-type potassium (KM) channels or inward-rectifying potassium (Kir) channels. Unlike KM channels, Kir channels enhance bistability. Combined with CaL channels, KM and Kir channels promote different types of bistability, with distinct robustness, and function. An analysis of their inward/outward properties revealed that their distinct steady-state currents explain this contrast. Altogether, the complementary of CaL and Kir channels creates a reliable possible pathway for central sensitization in the dorsal horn. <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('2411.14107v1-abstract-full').style.display = 'none'; document.getElementById('2411.14107v1-abstract-short').style.display = 'inline';">△ Less</a> </span> </p> <p class="is-size-7"><span class="has-text-black-bis has-text-weight-semibold">Submitted</span> 21 November, 2024; <span class="has-text-black-bis has-text-weight-semibold">originally announced</span> November 2024. </p> </li> <li class="arxiv-result"> <div class="is-marginless"> <p class="list-title is-inline-block"><a href="https://arxiv.org/abs/2405.02038">arXiv:2405.02038</a> <span> [<a href="https://arxiv.org/pdf/2405.02038">pdf</a>, <a href="https://arxiv.org/format/2405.02038">other</a>] </span> </p> <div class="tags is-inline-block"> <span class="tag is-small is-link tooltip is-tooltip-top" data-tooltip="Neurons and Cognition">q-bio.NC</span> <span class="tag is-small is-grey tooltip is-tooltip-top" data-tooltip="Mathematical Physics">math-ph</span> <span class="tag is-small is-grey tooltip is-tooltip-top" data-tooltip="Cell Behavior">q-bio.CB</span> </div> </div> <p class="title is-5 mathjax"> Dimensionality reduction of neuronal degeneracy reveals two interfering physiological mechanisms </p> <p class="authors"> <span class="search-hit">Authors:</span> <a href="/search/q-bio?searchtype=author&query=Fyon%2C+A">Arthur Fyon</a>, <a href="/search/q-bio?searchtype=author&query=Franci%2C+A">Alessio Franci</a>, <a href="/search/q-bio?searchtype=author&query=Sacr%C3%A9%2C+P">Pierre Sacr茅</a>, <a href="/search/q-bio?searchtype=author&query=Drion%2C+G">Guillaume Drion</a> </p> <p class="abstract mathjax"> <span class="has-text-black-bis has-text-weight-semibold">Abstract</span>: <span class="abstract-short has-text-grey-dark mathjax" id="2405.02038v1-abstract-short" style="display: inline;"> Neuronal systems maintain stable functions despite large variability in their physiological components. Ion channel expression, in particular, is highly variable in neurons exhibiting similar electrophysiological phenotypes, which poses questions regarding how specific ion channel subsets reliably shape neuron intrinsic properties. Here, we use detailed conductance-based modeling to explore the or… <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('2405.02038v1-abstract-full').style.display = 'inline'; document.getElementById('2405.02038v1-abstract-short').style.display = 'none';">▽ More</a> </span> <span class="abstract-full has-text-grey-dark mathjax" id="2405.02038v1-abstract-full" style="display: none;"> Neuronal systems maintain stable functions despite large variability in their physiological components. Ion channel expression, in particular, is highly variable in neurons exhibiting similar electrophysiological phenotypes, which poses questions regarding how specific ion channel subsets reliably shape neuron intrinsic properties. Here, we use detailed conductance-based modeling to explore the origin of stable neuronal function from variable channel composition. Using dimensionality reduction, we uncover two principal dimensions in the channel conductance space that capture most of the variance of the observed variability. Those two dimensions correspond to two physiologically relevant sources of variability that can be explained by feedback mechanisms underlying regulation of neuronal activity, providing quantitative insights into how channel composition links to neuronal electrophysiological activity. These insights allowed us to understand and design a model-independent, reliable neuromodulation rule for variable neuronal populations. <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('2405.02038v1-abstract-full').style.display = 'none'; document.getElementById('2405.02038v1-abstract-short').style.display = 'inline';">△ Less</a> </span> </p> <p class="is-size-7"><span class="has-text-black-bis has-text-weight-semibold">Submitted</span> 3 May, 2024; <span class="has-text-black-bis has-text-weight-semibold">originally announced</span> May 2024. </p> </li> <li class="arxiv-result"> <div class="is-marginless"> <p class="list-title is-inline-block"><a href="https://arxiv.org/abs/1602.03493">arXiv:1602.03493</a> <span> [<a href="https://arxiv.org/pdf/1602.03493">pdf</a>, <a href="https://arxiv.org/format/1602.03493">other</a>] </span> </p> <div class="tags is-inline-block"> <span class="tag is-small is-link tooltip is-tooltip-top" data-tooltip="Neurons and Cognition">q-bio.NC</span> </div> <div class="is-inline-block" style="margin-left: 0.5rem"> <div class="tags has-addons"> <span class="tag is-dark is-size-7">doi</span> <span class="tag is-light is-size-7"><a class="" href="https://doi.org/10.1109/CISS.2016.7460563">10.1109/CISS.2016.7460563 <i class="fa fa-external-link" aria-hidden="true"></i></a></span> </div> </div> </div> <p class="title is-5 mathjax"> Winning versus losing during gambling and its neural correlates </p> <p class="authors"> <span class="search-hit">Authors:</span> <a href="/search/q-bio?searchtype=author&query=Sacr%C3%A9%2C+P">Pierre Sacr茅</a>, <a href="/search/q-bio?searchtype=author&query=Kerr%2C+M+S+D">Matthew S. D. Kerr</a>, <a href="/search/q-bio?searchtype=author&query=Subramanian%2C+S">Sandya Subramanian</a>, <a href="/search/q-bio?searchtype=author&query=Kahn%2C+K">Kevin Kahn</a>, <a href="/search/q-bio?searchtype=author&query=Gonzalez-Martinez%2C+J">Jorge Gonzalez-Martinez</a>, <a href="/search/q-bio?searchtype=author&query=Johnson%2C+M+A">Matthew A. Johnson</a>, <a href="/search/q-bio?searchtype=author&query=Gale%2C+J+T">John T. Gale</a>, <a href="/search/q-bio?searchtype=author&query=Sarma%2C+S+V">Sridevi V. Sarma</a> </p> <p class="abstract mathjax"> <span class="has-text-black-bis has-text-weight-semibold">Abstract</span>: <span class="abstract-short has-text-grey-dark mathjax" id="1602.03493v1-abstract-short" style="display: inline;"> Humans often make decisions which maximize an internal utility function. For example, humans often maximize their expected reward when gambling and this is considered as a "rational" decision. However, humans tend to change their betting strategies depending on how they "feel". If someone has experienced a losing streak, they may "feel" that they are more likely to win on the next hand even though… <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('1602.03493v1-abstract-full').style.display = 'inline'; document.getElementById('1602.03493v1-abstract-short').style.display = 'none';">▽ More</a> </span> <span class="abstract-full has-text-grey-dark mathjax" id="1602.03493v1-abstract-full" style="display: none;"> Humans often make decisions which maximize an internal utility function. For example, humans often maximize their expected reward when gambling and this is considered as a "rational" decision. However, humans tend to change their betting strategies depending on how they "feel". If someone has experienced a losing streak, they may "feel" that they are more likely to win on the next hand even though the odds of the game have not changed. That is, their decisions are driven by their emotional state. In this paper, we investigate how the human brain responds to wins and losses during gambling. Using a combination of local field potential recordings in human subjects performing a financial decision-making task, spectral analyses, and non-parametric cluster statistics, we investigated whether neural responses in different cognitive and limbic brain areas differ between wins and losses after decisions are made. In eleven subjects, the neural activity modulated significantly between win and loss trials in one brain region: the anterior insula ($p=0.01$). In particular, gamma activity (30-70 Hz) increased in the anterior insula when subjects just realized that they won. Modulation of metabolic activity in the anterior insula has been observed previously in functional magnetic resonance imaging studies during decision making and when emotions are elicited. However, our study is able to characterize temporal dynamics of electrical activity in this brain region at the millisecond resolution while decisions are made and after outcomes are revealed. <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('1602.03493v1-abstract-full').style.display = 'none'; document.getElementById('1602.03493v1-abstract-short').style.display = 'inline';">△ Less</a> </span> </p> <p class="is-size-7"><span class="has-text-black-bis has-text-weight-semibold">Submitted</span> 10 February, 2016; <span class="has-text-black-bis has-text-weight-semibold">originally announced</span> February 2016. </p> </li> <li class="arxiv-result"> <div class="is-marginless"> <p class="list-title is-inline-block"><a href="https://arxiv.org/abs/1507.02716">arXiv:1507.02716</a> <span> [<a href="https://arxiv.org/pdf/1507.02716">pdf</a>, <a href="https://arxiv.org/format/1507.02716">other</a>] </span> </p> <div class="tags is-inline-block"> <span class="tag is-small is-link tooltip is-tooltip-top" data-tooltip="Neurons and Cognition">q-bio.NC</span> </div> <div class="is-inline-block" style="margin-left: 0.5rem"> <div class="tags has-addons"> <span class="tag is-dark is-size-7">doi</span> <span class="tag is-light is-size-7"><a class="" href="https://doi.org/10.1109/EMBC.2015.7319444">10.1109/EMBC.2015.7319444 <i class="fa fa-external-link" aria-hidden="true"></i></a></span> </div> </div> </div> <p class="title is-5 mathjax"> Electrical neurostimulation for chronic pain: on selective relay of sensory neural activities in myelinated nerve fibers </p> <p class="authors"> <span class="search-hit">Authors:</span> <a href="/search/q-bio?searchtype=author&query=Sacr%C3%A9%2C+P">Pierre Sacr茅</a>, <a href="/search/q-bio?searchtype=author&query=Sarma%2C+S+V">Sridevi V. Sarma</a>, <a href="/search/q-bio?searchtype=author&query=Guan%2C+Y">Yun Guan</a>, <a href="/search/q-bio?searchtype=author&query=Anderson%2C+W+S">William S. Anderson</a> </p> <p class="abstract mathjax"> <span class="has-text-black-bis has-text-weight-semibold">Abstract</span>: <span class="abstract-short has-text-grey-dark mathjax" id="1507.02716v1-abstract-short" style="display: inline;"> Chronic pain affects about 100 million adults in the US. Despite their great need, neuropharmacology and neurostimulation therapies for chronic pain have been associated with suboptimal efficacy and limited long-term success, as their mechanisms of action are unclear. Yet current computational models of pain transmission suffer from several limitations. In particular, dorsal column models do not i… <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('1507.02716v1-abstract-full').style.display = 'inline'; document.getElementById('1507.02716v1-abstract-short').style.display = 'none';">▽ More</a> </span> <span class="abstract-full has-text-grey-dark mathjax" id="1507.02716v1-abstract-full" style="display: none;"> Chronic pain affects about 100 million adults in the US. Despite their great need, neuropharmacology and neurostimulation therapies for chronic pain have been associated with suboptimal efficacy and limited long-term success, as their mechanisms of action are unclear. Yet current computational models of pain transmission suffer from several limitations. In particular, dorsal column models do not include the fundamental underlying sensory activity traveling in these nerve fibers. We developed a (simple) simulation test bed of electrical neurostimulation of myelinated nerve fibers with underlying sensory activity. This paper reports our findings so far. Interactions between stimulation-evoked and underlying activities are mainly due to collisions of action potentials and losses of excitability due to the refractory period following an action potential. In addition, intuitively, the reliability of sensory activity decreases as the stimulation frequency increases. This first step opens the door to a better understanding of pain transmission and its modulation by neurostimulation therapies. <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('1507.02716v1-abstract-full').style.display = 'none'; document.getElementById('1507.02716v1-abstract-short').style.display = 'inline';">△ Less</a> </span> </p> <p class="is-size-7"><span class="has-text-black-bis has-text-weight-semibold">Submitted</span> 9 July, 2015; <span class="has-text-black-bis has-text-weight-semibold">originally announced</span> July 2015. </p> </li> <li class="arxiv-result"> <div class="is-marginless"> <p class="list-title is-inline-block"><a href="https://arxiv.org/abs/1211.7317">arXiv:1211.7317</a> <span> [<a href="https://arxiv.org/pdf/1211.7317">pdf</a>, <a href="https://arxiv.org/format/1211.7317">other</a>] </span> </p> <div class="tags is-inline-block"> <span class="tag is-small is-link tooltip is-tooltip-top" data-tooltip="Dynamical Systems">math.DS</span> <span class="tag is-small is-grey tooltip is-tooltip-top" data-tooltip="Quantitative Methods">q-bio.QM</span> </div> <div class="is-inline-block" style="margin-left: 0.5rem"> <div class="tags has-addons"> <span class="tag is-dark is-size-7">doi</span> <span class="tag is-light is-size-7"><a class="" href="https://doi.org/10.1007/978-94-017-9047-5_3">10.1007/978-94-017-9047-5_3 <i class="fa fa-external-link" aria-hidden="true"></i></a></span> </div> </div> </div> <p class="title is-5 mathjax"> Sensitivity analysis of circadian entrainment in the space of phase response curves </p> <p class="authors"> <span class="search-hit">Authors:</span> <a href="/search/q-bio?searchtype=author&query=Sacr%C3%A9%2C+P">Pierre Sacr茅</a>, <a href="/search/q-bio?searchtype=author&query=Sepulchre%2C+R">Rodolphe Sepulchre</a> </p> <p class="abstract mathjax"> <span class="has-text-black-bis has-text-weight-semibold">Abstract</span>: <span class="abstract-short has-text-grey-dark mathjax" id="1211.7317v2-abstract-short" style="display: inline;"> Sensitivity analysis is a classical and fundamental tool to evaluate the role of a given parameter in a given system characteristic. Because the phase response curve is a fundamental input--output characteristic of oscillators, we developed a sensitivity analysis for oscillator models in the space of phase response curves. The proposed tool can be applied to high-dimensional oscillator models with… <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('1211.7317v2-abstract-full').style.display = 'inline'; document.getElementById('1211.7317v2-abstract-short').style.display = 'none';">▽ More</a> </span> <span class="abstract-full has-text-grey-dark mathjax" id="1211.7317v2-abstract-full" style="display: none;"> Sensitivity analysis is a classical and fundamental tool to evaluate the role of a given parameter in a given system characteristic. Because the phase response curve is a fundamental input--output characteristic of oscillators, we developed a sensitivity analysis for oscillator models in the space of phase response curves. The proposed tool can be applied to high-dimensional oscillator models without facing the curse of dimensionality obstacle associated with numerical exploration of the parameter space. Application of this tool to a state-of-the-art model of circadian rhythms suggests that it can be useful and instrumental to biological investigations. <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('1211.7317v2-abstract-full').style.display = 'none'; document.getElementById('1211.7317v2-abstract-short').style.display = 'inline';">△ Less</a> </span> </p> <p class="is-size-7"><span class="has-text-black-bis has-text-weight-semibold">Submitted</span> 24 January, 2013; <span class="has-text-black-bis has-text-weight-semibold">v1</span> submitted 30 November, 2012; <span class="has-text-black-bis has-text-weight-semibold">originally announced</span> November 2012. </p> <p class="comments is-size-7"> <span class="has-text-black-bis has-text-weight-semibold">Comments:</span> <span class="has-text-grey-dark mathjax">22 pages, 8 figures. Correction of a mistake in Definition 2.1. arXiv admin note: text overlap with arXiv:1206.4144</span> </p> </li> </ol> <div class="is-hidden-tablet">  <span class="help" style="display: inline-block;"><a href="https://github.com/arXiv/arxiv-search/releases">Search v0.5.6 released 2020-02-24</a>  </span> </div> </div> </main> <footer> <div class="columns is-desktop" role="navigation" aria-label="Secondary">  <div class="column"> <div class="columns"> <div class="column"> <ul class="nav-spaced"> <li><a href="https://info.arxiv.org/about">About</a></li> <li><a href="https://info.arxiv.org/help">Help</a></li> </ul> </div> <div class="column"> <ul class="nav-spaced"> <li> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512" class="icon filter-black" role="presentation"><title>contact arXiv</title><desc>Click here to contact arXiv</desc><path d="M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z"/></svg> <a href="https://info.arxiv.org/help/contact.html"> Contact</a> </li> <li> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512" class="icon filter-black" role="presentation"><title>subscribe to arXiv mailings</title><desc>Click here to subscribe</desc><path d="M476 3.2L12.5 270.6c-18.1 10.4-15.8 35.6 2.2 43.2L121 358.4l287.3-253.2c5.5-4.9 13.3 2.6 8.6 8.3L176 407v80.5c0 23.6 28.5 32.9 42.5 15.8L282 426l124.6 52.2c14.2 6 30.4-2.9 33-18.2l72-432C515 7.8 493.3-6.8 476 3.2z"/></svg> <a href="https://info.arxiv.org/help/subscribe"> Subscribe</a> </li> </ul> </div> </div> </div>   <div class="column"> <div class="columns"> <div class="column"> <ul class="nav-spaced"> <li><a href="https://info.arxiv.org/help/license/index.html">Copyright</a></li> <li><a href="https://info.arxiv.org/help/policies/privacy_policy.html">Privacy Policy</a></li> </ul> </div> <div class="column sorry-app-links"> <ul class="nav-spaced"> <li><a href="https://info.arxiv.org/help/web_accessibility.html">Web Accessibility Assistance</a></li> <li> <p class="help"> <a class="a11y-main-link" href="https://status.arxiv.org" target="_blank">arXiv Operational Status <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 256 512" class="icon filter-dark_grey" role="presentation"><path d="M224.3 273l-136 136c-9.4 9.4-24.6 9.4-33.9 0l-22.6-22.6c-9.4-9.4-9.4-24.6 0-33.9l96.4-96.4-96.4-96.4c-9.4-9.4-9.4-24.6 0-33.9L54.3 103c9.4-9.4 24.6-9.4 33.9 0l136 136c9.5 9.4 9.5 24.6.1 34z"/></svg></a><br> Get status notifications via <a class="is-link" href="https://subscribe.sorryapp.com/24846f03/email/new" target="_blank"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512" class="icon filter-black" role="presentation"><path d="M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z"/></svg>email</a> or <a class="is-link" href="https://subscribe.sorryapp.com/24846f03/slack/new" target="_blank"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512" class="icon filter-black" role="presentation"><path d="M94.12 315.1c0 25.9-21.16 47.06-47.06 47.06S0 341 0 315.1c0-25.9 21.16-47.06 47.06-47.06h47.06v47.06zm23.72 0c0-25.9 21.16-47.06 47.06-47.06s47.06 21.16 47.06 47.06v117.84c0 25.9-21.16 47.06-47.06 47.06s-47.06-21.16-47.06-47.06V315.1zm47.06-188.98c-25.9 0-47.06-21.16-47.06-47.06S139 32 164.9 32s47.06 21.16 47.06 47.06v47.06H164.9zm0 23.72c25.9 0 47.06 21.16 47.06 47.06s-21.16 47.06-47.06 47.06H47.06C21.16 243.96 0 222.8 0 196.9s21.16-47.06 47.06-47.06H164.9zm188.98 47.06c0-25.9 21.16-47.06 47.06-47.06 25.9 0 47.06 21.16 47.06 47.06s-21.16 47.06-47.06 47.06h-47.06V196.9zm-23.72 0c0 25.9-21.16 47.06-47.06 47.06-25.9 0-47.06-21.16-47.06-47.06V79.06c0-25.9 21.16-47.06 47.06-47.06 25.9 0 47.06 21.16 47.06 47.06V196.9zM283.1 385.88c25.9 0 47.06 21.16 47.06 47.06 0 25.9-21.16 47.06-47.06 47.06-25.9 0-47.06-21.16-47.06-47.06v-47.06h47.06zm0-23.72c-25.9 0-47.06-21.16-47.06-47.06 0-25.9 21.16-47.06 47.06-47.06h117.84c25.9 0 47.06 21.16 47.06 47.06 0 25.9-21.16 47.06-47.06 47.06H283.1z"/></svg>slack</a> </p> </li> </ul> </div> </div> </div>  </div> </footer> <script src="https://static.arxiv.org/static/base/1.0.0a5/js/member_acknowledgement.js"></script> </body> </html>

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