Depression (Major Depressive Disorder)

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<div data-widget-def="UX3HTMLWidget" data-widget-id="1f50ccd1-d4c9-4c19-9f9b-fb5c5c798391" class="slide-text"> <h6 class="text-white">Center for Workplace Mental Health</h6> <p> Depression: A Costly Condition for Businesses: <a class="text-white" target="_blank" href="http://workplacementalhealth.org/Mental-Health-Topics/Depression" aria-label="Learn more about Depression: A Costly Condition for Businesses"><strong>Learn more</strong></a> and <a class="link" target="_blank" href="http://workplacementalhealth.org/Employer-Resources/Infographic-Depression"><strong>view the infographic</strong></a> </p> <h6 class="text-white">Help With Depression</h6> <p> Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. Fortunately, it is also treatable. <a class="link" target="_blank" href="https://www.psychiatry.org/patients-families/depression" aria-label="Learn more about major depressive disorder"><strong>Learn More</strong></a> </p> </div> </div> </div> </div><div class="swiper-slide"> <div class="text-onDark"> <div data-widget-def="ux3-general-image" data-widget-id="d0a4158d-4a9d-4b57-a761-775ef26e2f2b" class="slide-image"> <img id="" alt="" src="/pb-assets/images/backgrounds/man-sofa-wall_bg-1585057160720.jpg"/> </div> <div class="dark-transparent-bg"> <div class="container-fluid"><div class="row"><div class="col-12 col-sm-4 col-lg-3"> <div data-widget-def="UX3HTMLWidget" data-widget-id="54c408e2-f9b3-4771-993e-988198adb33f" class="center"> <style> .img-cover-bipolar { max-height: 300px; max-width: 150px; } </style> <img class="img-cover-bipolar" src="https://psychiatryonline.org/na101/home/literatum/publisher/app/journals/content/ajp/2020/ajp.2020.177.issue-5/ajp.2020.177.issue-5/20200501/ajp.2020.177.issue-5.cover.jpg" alt="American Journal of Psychiatry, Volume 177, Issue 5"> <br> <br> <br> </div> </div><div class="col-12 col-sm-8 col-lg-9"> <div data-widget-def="UX3HTMLWidget" data-widget-id="e3c085de-11ea-495d-85c2-981afc2933d8" class="slide-text"> <h6 class="text-white"><em>The American Journal of Psychiatry</em></h6> <p><a class="link" href="https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2019.19090911" title="The Rearing Environment and Risk for Major Depression: A Swedish National High-Risk Home-Reared and Adopted-Away Co-Sibling Control Study">The Rearing Environment and Risk for Major Depression: A Swedish National High-Risk Home-Reared and Adopted-Away Co-Sibling Control Study</a></p> Kenneth S. Kendler, M.D., Henrik Ohlsson, Ph.D., Jan Sundquist, M.D., Ph.D., Kristina Sundquist, M.D., Ph.D. <hr> <p><a class="link" href="https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2020.20020186" title="Is Depression Nature or Nurture? Yes">Is Depression Nature or Nurture? Yes</a></p> Myrna M. Weissman, Ph.D. <br> <hr> <p>More from APA: <a class="link" href="https://www.psychiatry.org/newsroom/news-releases/a-child-s-home-environment-can-impact-the-risk-of-developing-depression">A Child’s Home Environment Can Impact the Risk of Developing Depression</a></p> </div> </div></div></div> </div> </div> </div><div class="swiper-slide"> <div class="text-onDark"> <div data-widget-def="ux3-general-image" data-widget-id="3ad850f2-d297-40e3-a65b-2424d3ab74a9" class="slide-image"> <img id="" alt="" src="/pb-assets/images/backgrounds/_mdd/MDD_background-1-1547571640420.jpg"/> </div> <div class="dark-transparent-bg"> <div data-widget-def="UX3HTMLWidget" data-widget-id="41ccfd45-f5a6-4c39-98ed-beb69ec4c230" class="slide-text"> <style> .img__schizo { float: right; } </style> <h6 class="text-white"><em>Gabbard’s Treatments of Psychiatric Disorders, 5th Edition</em></h6> <p><img class="img__schizo" src="/pb-assets/images/backgrounds/_mdd/Gabbard_TPD-5E_150-1546273097267.jpg" alt="Gabbard’s Treatments of Psychiatric Disorders"> Chapter 14 of this textbook reviews the pharmacological landscape and experimental horizon in Major Depressive Disorder (MDD).</p> <p> Continue reading online in <a class="link" target="_blank" href="https://psychiatryonline.org/doi/10.1176/appi.books.9781585625048.gg14">Chapter 14: Pharmacological and Somatic Treatments for Major Depressive Disorder</a>. </p> <p> <a class="btn__schizo" href="https://www.appi.org/Gabbards_Treatments_of_Psychiatric_Disorders_Fifth_Edition">Buy Print</a> </p> </div> </div> </div> </div></div><div class="swiper-pagination"></div></div><div class="swiper-button-container"><div class="swiper-button-prev"></div><div class="swiper-button-next"></div></div><span id="afterSlideshow-81c" tabindex="-1"></span></div> </div> </div><div class="order-sm-1 order-lg-2 col-12 col-lg-4 mb-20"> <div data-widget-def="UX3HTMLWidget" data-widget-id="652caac6-e021-4a21-81e8-6da187289217" class="theme-note border-bottom right mb-32 "> <h1 class="text-title-3 mb-8">What Is Depression?</h1> <p>Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. <br> <br> Fortunately, it is also treatable. Depression causes feelings of sadness and/or a loss of interest in activities once enjoyed. It can lead to a variety of emotional and physical problems and can decrease a person’s ability to function at work and at home.</p> <p> <a class="btn__schizo" target="_blank" href="https://www.psychiatry.org/patients-families/depression/what-is-depression" aria-label="Learn more about depression">Learn More</a> </p> </div> </div> </div> </div></div></div> <div class="container-fluid"><div class="row"><div class="col-12 col-md-7 col-lg-8 mt-40 mb-20"> <div data-widget-def="UX3HTMLWidget" data-widget-id="7ae02174-6f1b-4177-8aba-f0482af29b0d" class="custom-page margin-bottom-15 margin-top-15"> <div class="theme-note mt-12 mb-20"> <p> Browse APA journals and books to view relevant content on <b><a class="link" href="https://psychiatryonline.org/action/doSearch?AllField=mdd&startPage=0&sortBy=relevancy">MDD</a></b> and narrow results or sort by publication date </p> </div> </div> <div class="multi-search"><ul class="list-unstyled"><li class="multi-search__item"><div class="card border-bottom border-gray mb-32 pb-24 pn "><div class="card-content"><div class="card-header text-dark-gray"><div class="d-flex align-items-center meta-wrapper"><a href="/journal/pn" class="card-category btn btn-primary text-micro-uppercase brand-tag px-12 mr-12">PN</a><span class="overline text-micro-uppercase text-deep-gray px-12 border-right border-left border-gray"><span class="pr-12 mr-12 border-right border-gray d-inline-block">1 Dec 2024</span><span>Clinical & Research</span></span></div><h2 class="card-title text-title-5 text-deep-gray my-8"><a href="/doi/10.1176/appi.pn.2024.12.12.27" class="text-reset animation-underline">Special Report: Precise, Personalized, and Preventive Psychiatry</a></h2></div><div class="card-footer text-dark-gray"><div class="card-contribs authors text-reset"><ul title="list of authors" class="list-inline" data-truncate-see-more-hidden-text="for Special Report: Precise, Personalized, and Preventive Psychiatry"><li class="list-inline-item"><a href="/author/Niculescu%2C+Alexander+B" title="Alexander B. 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Voineskos</a>, M.D., Ph.D.</li></ul></div></div></div></div></li></ul></div>  <div id='div-gpt-ad-1453495359999-5'> <script type='text/javascript' nonce="8e9175b7c43cce6e-SIN"> googletag.cmd.push(function() { googletag.display('div-gpt-ad-1453495359999-5'); }); </script> </div> <div class="custom-page"> <div data-widget-def="ux3-layout-widget" data-widget-id="8ddb5f51-f03b-40a4-a2f1-dce5e31b6422" class="card--shadow card-small border my-40"> <div class="container-fluid"><div class="row"><div class="col-lg-9 col-sm-12 col-sx-12"> <div data-widget-def="UX3HTMLWidget" data-widget-id="6222470e-4d3a-4fa1-ae4d-fc74afe79b02" class="margin-top-15 margin-bottom-15"> <h6 class=""> Patient Story: Depression </h6> <p>Trish was a 51-year-old woman who was brought to the emergency room by her husband. She said, “I feel like killing myself.” She had lost her interest in life about four months before. During that time, she reported depression every day for most of the day. Symptoms had been getting worse for months... <a class="link" target="_blank" href="https://www.psychiatry.org/patients-families/depression/patient-story">continue reading</a></p> <h6>About This Story</h6> This patient story is excerpted from <a class="link" target="_blank" href="https://psychiatryonline.org/doi/book/10.1176/appi.books.9781615370740"><em>Understanding Mental Disorders: A Patient And Family Resource</em>.</a> <p>Based on the latest, fifth edition of the <em>Diagnostic and Statistical Manual of Mental Disorders</em>—known as DSM-5®—<em>Understanding Mental Disorders</em> provides valuable insight on what to expect from an illness and its treatment—and will help readers recognize symptoms, know when to seek help, and get the right care. </p> <p> <a class="btn__schizo" target="_blank" href="https://www.appi.org/course/book/subscription/journalsubscription/id-3361/understanding_mental_disorders" aria-label="Buy Understanding Mental Disorders: A Patient And Family Resource in print">Buy Print</a> </p> </div> </div><div class="col-lg-3 col-sm-12 col-sx-12"> <div data-widget-def="UX3CoverImage" data-widget-id="361e1181-159e-4828-af42-5f01bb7d73c2" class="margin-top-15"> <div class="cover-image d-flex justify-content-center flex-column"><div data-is-viewable="" class="cover-image__image"><a href="/doi/book/10.1176/appi.books.9781615370740" title="Go to Understanding Mental Disorders: A Patient and Family Resource" class="d-block"><img src="/cms/10.1176/appi.books.9781615370740/asset/16306d67-9316-06d6-7931-306d67793163/appi.books.9781615370740.cover.jpg" alt="Go to Understanding Mental Disorders: A Patient and Family Resource" loading="lazy"/></a></div></div> </div> </div></div></div> </div> </div> </div><div class="col-12 col-md-5 col-lg-4 mb-20"> <div class="adplaceholder exists d-flex justify-content-center align-items-center my-40"> <div class="adplaceholder__title overline">Advertisement</div>  <div id="div-gpt-ad-1453495359999-1"> <script type="text/javascript" nonce="8e9175b7c43cce6e-SIN"> googletag.cmd.push(function() { googletag.display('div-gpt-ad-1453495359999-1'); }); </script> </div> </div> <div data-widget-def="UX3HTMLWidget" data-widget-id="5dcf1753-9ed4-474b-8c33-0628f76b754a" class="border shadow my-40 p-12"> <h6 class=""> Resource Centers </h6> <p>View curated content from our journals, books, textbooks, and other APA resources:</p> <ul> <li> <a class="link" href="/adhd"><strong>Attention Deficit Disorder (ADHD)</strong></a> </li> <li> <a class="link" href="/bipolar"><strong>Bipolar Disorder</strong></a> </li> <li> <a class="link" href="/mdd"><strong>Depression (MDD)</strong></a> </li> <li> <a class="link" href="/gun-violence"><strong>Gun Violence</strong></a> </li> <li> <a class="link" href="/schizophrenia"><strong>Schizophrenia</strong></a> </li> </ul> </div> <div data-widget-def="UX3HTMLWidget" data-widget-id="4db29e65-89a1-4abf-bc02-a9477f1ef04c" class="border shadow my-40 p-12"> <h6 class=""> Find a Psychiatrist </h6> <p> A psychiatrist specializes in the diagnosis, treatment, and prevention of mental illness and substance abuse disorders. 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Forgot your password?</p> <p class="raa-form__note">Enter your email address below and we will send you the reset instructions</p> <form action="/action/requestResetPassword" class="request-reset-password-form raa-form" method="post"><input type="hidden" name="requestResetPassword" value="true" /> <div class="form-row"> <div class="col"> <div class="form-group"> <label for="e63e610e-8d18-4fc9-94c5-b45c6c6b20d6.email"> Email <span>*</span> </label> <input id="e63e610e-8d18-4fc9-94c5-b45c6c6b20d6.email" class="form-control" type="email" name="email" value="" placeholder="Enter your email"required="true" /> </div> </div> </div> <div class="form-row"> <div class="password-recaptcha-ajax"></div> </div> <div class="form-row"> <div class="col text-right"> <button type="submit" class="btn btn-submit"><span>Submit</span><span aria-hidden="true" class="icon-arrow-right ml-3"></span></button> </div> </div></form> <div class="alert alert-success d-none"> <p>If the address matches an existing account you will receive an email with instructions to reset your password.</p> </div> </div> </div> </div> </div> <div tabindex="-1" id="modal--verifyPhone" aria-labelledby="modalverifyPhoneLabel" class="modal fade" aria-modal="true" role="dialog"> <div role="document" class="modal-dialog modal-fullscreen-sm-down"> <div class="modal-content"> <div class="modal-header"> <h2 id="modalverifyPhoneLabel" class="modal-title h5">Change Password </h2> <button type="button" data-dismiss="modal" aria-label="close" class="close"> <span aria-hidden="true">x</span><span class="sr-only">Close</span> </button> </div> <div class="modal-body"> <form action="/action/verifyPhoneNumber" method="post"><input type="hidden" name="submit" value="submit" /> <div class="alert alert-danger d-none"></div> <div class="form-row"> <div class="col"> <div class="form-group"> <label for="95732d58-22cc-4830-a98c-0b9d1a59a066-code">Enter the verification code</label> <input id="95732d58-22cc-4830-a98c-0b9d1a59a066-code" class="form-control" type="text" name="verificationCode" value="" size="15"pattern="^[0-9]{6}$"required="required" /> </div> </div> </div> <div class="form-row"> <div class="col text-right"> <button type="submit" class="btn btn-submit"> <span>Submit</span> <span aria-hidden="true" class="icon-arrow-right ml-3"></span> </button> </div> </div></form> </div> </div> <div class="alert alert-success d-none"> <h5>Congrats!</h5> <p>Your Phone has been verified</p> </div> </div> </div> </div> <div class="pb-las"> <style type="text/css"> .cookie-notice { display: none; position: fixed; bottom: 0; z-index: 1000; padding: 15px; background: #333; color: #fff; max-height: 200px; overflow: scroll; } .cookie-notice a { color: #fff; text-decoration: underline; } .closebtn { float: right; margin: 0 0 7px 7px; padding: 2px 5px; border: 1px solid #fff; color: white; font-weight: bold; font-size: 22px; line-height: 20px; cursor: pointer; transition: 0.3s; } </style> <div class="cookie-notice"> <span class="closebtn" onclick="this.parentElement.style.display='none';">×</span> <p>As described within the American Psychiatric Association (APA)'s <a href="/action/clickThrough?id=501153&url=%2Faction%2FclickThrough%3Fid%3D501152%26amp%3Burl%3Dhttps%253A%252F%252Fpsychiatryonline.org%252Fprivacypolicy%26amp%3Bloc%3D%252F%26amp%3BplaceholderId%3D501117%26amp%3BproductId%3D1010&loc=%2Fmdd&placeholderId=501118&productId=1010" class="link">Privacy Policy</a> and <a href="/action/clickThrough?id=501153&url=%2Faction%2FclickThrough%3Fid%3D501152%26amp%3Burl%3Dhttps%253A%252F%252Fpsychiatryonline.org%252Ftermsofuse%26amp%3Bloc%3D%252F%26amp%3BplaceholderId%3D501117%26amp%3BproductId%3D1010&loc=%2Fmdd&placeholderId=501118&productId=1010" class="link">Terms of Use</a>, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences. 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