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vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="开关目录" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" > 开关目录 </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading">阿那曲唑</h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" 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data-title="اناستازول" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target">تۆرکجه</a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 捷克语" lang="cs" hreflang="cs" data-title="Anastrozol" data-language-autonym="Čeština" data-language-local-name="捷克语" class="interlanguage-link-target">Čeština</a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Anastrosol" title="Anastrosol – 威尔士语" lang="cy" hreflang="cy" data-title="Anastrosol" data-language-autonym="Cymraeg" data-language-local-name="威尔士语" class="interlanguage-link-target">Cymraeg</a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 德语" lang="de" hreflang="de" data-title="Anastrozol" data-language-autonym="Deutsch" data-language-local-name="德语" class="interlanguage-link-target">Deutsch</a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Anastrozole" title="Anastrozole – 英语" lang="en" hreflang="en" data-title="Anastrozole" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target">English</a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 西班牙语" lang="es" hreflang="es" data-title="Anastrozol" data-language-autonym="Español" data-language-local-name="西班牙语" class="interlanguage-link-target">Español</a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 巴斯克语" lang="eu" hreflang="eu" data-title="Anastrozol" data-language-autonym="Euskara" data-language-local-name="巴斯克语" class="interlanguage-link-target">Euskara</a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A2%D9%86%D8%A7%D8%B3%D8%AA%D8%B1%D9%88%D8%B2%D9%88%D9%84" title="آناستروزول – 波斯语" lang="fa" hreflang="fa" data-title="آناستروزول" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target">فارسی</a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Anastrotsoli" title="Anastrotsoli – 芬兰语" lang="fi" hreflang="fi" data-title="Anastrotsoli" data-language-autonym="Suomi" data-language-local-name="芬兰语" class="interlanguage-link-target">Suomi</a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Anastrozole" title="Anastrozole – 法语" lang="fr" hreflang="fr" data-title="Anastrozole" data-language-autonym="Français" data-language-local-name="法语" class="interlanguage-link-target">Français</a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 加利西亚语" lang="gl" hreflang="gl" data-title="Anastrozol" data-language-autonym="Galego" data-language-local-name="加利西亚语" class="interlanguage-link-target">Galego</a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%B1%D5%B6%D5%A1%D5%BD%D5%BF%D6%80%D5%B8%D5%A6%D5%B8%D5%AC" title="Անաստրոզոլ – 亚美尼亚语" lang="hy" hreflang="hy" data-title="Անաստրոզոլ" data-language-autonym="Հայերեն" data-language-local-name="亚美尼亚语" class="interlanguage-link-target">Հայերեն</a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 印度尼西亚语" lang="id" hreflang="id" data-title="Anastrozol" data-language-autonym="Bahasa Indonesia" data-language-local-name="印度尼西亚语" class="interlanguage-link-target">Bahasa Indonesia</a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Anastrozolo" title="Anastrozolo – 意大利语" lang="it" hreflang="it" data-title="Anastrozolo" data-language-autonym="Italiano" data-language-local-name="意大利语" class="interlanguage-link-target">Italiano</a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%A2%E3%83%8A%E3%82%B9%E3%83%88%E3%83%AD%E3%82%BE%E3%83%BC%E3%83%AB" title="アナストロゾール – 日语" lang="ja" hreflang="ja" data-title="アナストロゾール" data-language-autonym="日本語" data-language-local-name="日语" class="interlanguage-link-target">日本語</a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%86%E0%AC%A8%E0%AC%BE%E0%AC%B7%E0%AD%8D%E0%AC%9F%E0%AD%8D%E0%AC%B0%E0%AD%8B%E0%AC%9C%E0%AD%8B%E0%AC%B2" title="ଆନାଷ୍ଟ୍ରୋଜୋଲ – 奥里亚语" lang="or" hreflang="or" data-title="ଆନାଷ୍ଟ୍ରୋଜୋଲ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="奥里亚语" class="interlanguage-link-target">ଓଡ଼ିଆ</a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 波兰语" lang="pl" hreflang="pl" data-title="Anastrozol" data-language-autonym="Polski" data-language-local-name="波兰语" class="interlanguage-link-target">Polski</a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 葡萄牙语" lang="pt" hreflang="pt" data-title="Anastrozol" data-language-autonym="Português" data-language-local-name="葡萄牙语" class="interlanguage-link-target">Português</a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%90%D0%BD%D0%B0%D1%81%D1%82%D1%80%D0%BE%D0%B7%D0%BE%D0%BB" title="Анастрозол – 俄语" lang="ru" hreflang="ru" data-title="Анастрозол" data-language-autonym="Русский" data-language-local-name="俄语" class="interlanguage-link-target">Русский</a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 塞尔维亚-克罗地亚语" lang="sh" hreflang="sh" data-title="Anastrozol" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="塞尔维亚-克罗地亚语" class="interlanguage-link-target">Srpskohrvatski / српскохрватски</a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 斯洛文尼亚语" lang="sl" hreflang="sl" data-title="Anastrozol" data-language-autonym="Slovenščina" data-language-local-name="斯洛文尼亚语" class="interlanguage-link-target">Slovenščina</a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Anastrozol" title="Anastrozol – 塞尔维亚语" lang="sr" hreflang="sr" data-title="Anastrozol" data-language-autonym="Српски / srpski" data-language-local-name="塞尔维亚语" class="interlanguage-link-target">Српски / srpski</a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%90%D0%BD%D0%B0%D1%81%D1%82%D1%80%D0%BE%D0%B7%D0%BE%D0%BB" title="Анастрозол – 乌克兰语" lang="uk" hreflang="uk" data-title="Анастрозол" data-language-autonym="Українська" data-language-local-name="乌克兰语" class="interlanguage-link-target">Українська</a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Anastrozole" title="Anastrozole – 越南语" lang="vi" hreflang="vi" data-title="Anastrozole" data-language-autonym="Tiếng Việt" data-language-local-name="越南语" class="interlanguage-link-target">Tiếng Việt</a></li> </ul> <div class="after-portlet after-portlet-lang"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q419143#sitelinks-wikipedia" title="编辑跨语言链接" class="wbc-editpage">编辑链接</a></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="命名空间"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul 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<div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="页面工具"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="外观"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">外观</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button 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div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title">阿那曲唑</caption><tbody><tr><td colspan="2" class="infobox-image"><a href="/wiki/File:Anastrozole.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c4/Anastrozole.svg/225px-Anastrozole.svg.png" decoding="async" width="225" height="151" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c4/Anastrozole.svg/338px-Anastrozole.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c4/Anastrozole.svg/450px-Anastrozole.svg.png 2x" data-file-width="512" data-file-height="343" /></a></td></tr><tr><td colspan="2" class="infobox-image"><a href="/wiki/File:Anastrozole-from-xtal-3D-balls.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Anastrozole-from-xtal-3D-balls.png/225px-Anastrozole-from-xtal-3D-balls.png" decoding="async" width="225" height="191" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Anastrozole-from-xtal-3D-balls.png/338px-Anastrozole-from-xtal-3D-balls.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Anastrozole-from-xtal-3D-balls.png/450px-Anastrozole-from-xtal-3D-balls.png 2x" data-file-width="1100" data-file-height="936" /></a></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">臨床資料</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/w/index.php?title=%E8%97%A5%E7%89%A9%E5%91%BD%E5%90%8D%E6%B3%95&action=edit&redlink=1" class="new" title="藥物命名法（页面不存在）">商品名</a>（英语：<a href="https://en.wikipedia.org/wiki/Drug_nomenclature" class="extiw" title="en:Drug nomenclature">Drug nomenclature</a>）</th><td class="infobox-data" style="">Arimidex,、Aremed及其他<a href="#cite_note-Drugs.com-1">[1]</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;">其他名稱</th><td class="infobox-data" style="">Anastrazole、anastrozol、ICI-D1033及ZD-1033</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%BE%8E%E5%9C%8B%E8%A1%9B%E7%94%9F%E7%B3%BB%E7%B5%B1%E8%97%A5%E5%B8%AB%E5%8D%94%E6%9C%83" title="美國衛生系統藥師協會">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="https://www.drugs.com/monograph/anastrozole.html">Monograph</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a></th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="https://medlineplus.gov/druginfo/meds/a696018.html">a696018</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E9%86%AB%E7%99%82%E7%94%A2%E5%93%81%E6%B3%95%E5%BE%8B%E8%A6%8F%E7%AF%84" title="醫療產品法律規範">核准狀況</a></th><td class="infobox-data" style=""><div class="plainlist"> <ul><li><abbr title="美国">美</abbr> <a href="/wiki/DailyMed" title="DailyMed">DailyMed</a>: <a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=Anastrozole">Anastrozole</a></li></ul></div> </td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E6%87%B7%E5%AD%95%E5%88%86%E7%B4%9A" title="懷孕分級">懷孕分級</a></th><td class="infobox-data" style=""><div class="plainlist"> <ul><li><abbr title="澳大利亚">澳</abbr>: <a href="/wiki/%E6%87%B7%E5%AD%95%E5%88%86%E7%B4%9A#澳洲" title="懷孕分級">C</a> </li> <li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%BB%99%E8%8D%AF%E9%80%94%E5%BE%84" title="给药途径">给药途径</a></th><td class="infobox-data" style=""><a href="/wiki/%E5%8F%A3%E6%9C%8D%E7%BB%99%E8%8D%AF" title="口服给药">口服給藥</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E8%8D%AF%E7%89%A9%E7%B1%BB%E5%88%AB" class="mw-redirect" title="药物类别">藥物類別</a>（英语：<a href="https://en.wikipedia.org/wiki/Drug_class" class="extiw" title="en:Drug class">Drug class</a>）</th><td class="infobox-data" style=""><a href="/w/index.php?title=%E8%8A%B3%E9%A6%99%E5%8C%96%E9%85%B6%E6%8A%91%E5%88%B6%E5%8A%91&action=edit&redlink=1" class="new" title="芳香化酶抑制劑（页面不存在）">芳香化酶抑制劑</a>（英语：<a href="https://en.wikipedia.org/wiki/Aromatase_inhibitor" class="extiw" title="en:Aromatase inhibitor">Aromatase inhibitor</a>），<a href="/w/index.php?title=%E6%8A%97%E9%9B%8C%E6%BF%80%E7%B4%A0&action=edit&redlink=1" class="new" title="抗雌激素（页面不存在）">抗雌激素</a>（英语：<a href="https://en.wikipedia.org/wiki/Antiestrogen" class="extiw" title="en:Antiestrogen">Antiestrogen</a>）</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E8%A7%A3%E5%89%96%E5%AD%A6%E6%B2%BB%E7%96%97%E5%AD%A6%E5%8F%8A%E5%8C%96%E5%AD%A6%E5%88%86%E7%B1%BB%E7%B3%BB%E7%BB%9F" title="解剖学治疗学及化学分类系统">ATC碼</a></th><td class="infobox-data" style=""><style data-mw-deduplicate="TemplateStyles:r82655520">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li><a href="/wiki/ATC%E4%BB%A3%E7%A0%81_(L02)" title="ATC代码 (L02)">L02BG03</a> (<a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=L02BG03">WHO</a>) </li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">法律規範狀態</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E9%86%AB%E7%99%82%E7%94%A2%E5%93%81%E6%B3%95%E5%BE%8B%E8%A6%8F%E7%AF%84" title="醫療產品法律規範">法律規範</a></th><td class="infobox-data" style=""><div class="plainlist"> <ul><li><abbr title="澳大利亚">澳</abbr>：<a href="/wiki/SUSMP" class="mw-redirect" title="SUSMP">限医生处方（S4）</a></li> <li><abbr title="英国">英</abbr>：<a href="/wiki/%E8%99%95%E6%96%B9%E8%97%A5" title="處方藥">处方药（℞-only）</a> (POM)</li> <li><abbr title="美国">美</abbr>：<a href="/wiki/%E8%99%95%E6%96%B9%E8%97%A5" title="處方藥">处方药（℞-only）</a></li></ul></div> </td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;"><a href="/wiki/%E8%8D%AF%E7%89%A9%E4%BB%A3%E8%B0%A2%E5%8A%A8%E5%8A%9B%E5%AD%A6" title="药物代谢动力学">藥物動力學</a>數據</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%94%9F%E7%89%A9%E5%88%A9%E7%94%A8%E5%BA%A6" title="生物利用度">生物利用度</a></th><td class="infobox-data" style="">尚不清楚 (但在試驗動物體內吸收良好)<a href="#cite_note-Lønning2003-2">[2]</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E8%A1%80%E6%B5%86%E8%9B%8B%E7%99%BD%E7%BB%93%E5%90%88" title="血浆蛋白结合">血漿蛋白結合率</a></th><td class="infobox-data" style="">40%<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E8%8D%AF%E7%89%A9%E4%BB%A3%E8%B0%A2" title="药物代谢">药物代谢</a></th><td class="infobox-data" style=""><a href="/wiki/%E8%82%9D%E8%87%9F" title="肝臟">肝臟</a> (~85%) (<a href="/wiki/%E7%83%B7%E5%9F%BA%E5%8C%96" title="烷基化">烷基化</a>、<a href="/wiki/%E7%BE%9F%E5%9F%BA%E5%8C%96" title="羟基化">羥基化</a>和<a href="/w/index.php?title=%E8%91%A1%E8%90%84%E9%86%A3%E9%86%9B%E9%85%B8%E5%8C%96&action=edit&redlink=1" class="new" title="葡萄醣醛酸化（页面不存在）">葡萄醣醛酸化</a>（英语：<a href="https://en.wikipedia.org/wiki/Glucuronidation" class="extiw" title="en:Glucuronidation">Glucuronidation</a>）)<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%94%9F%E7%89%A9%E5%8D%8A%E8%A1%B0%E6%9C%9F" title="生物半衰期">生物半衰期</a></th><td class="infobox-data" style="">40–50小時<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E6%8E%92%E6%B3%84%E4%BD%9C%E7%94%A8" title="排泄作用">排泄途徑</a></th><td class="infobox-data" style=""><a href="/wiki/%E5%B0%BF" title="尿">尿</a>液 (11%)<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">识别信息</th></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">IUPAC命名法</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;">2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)<a href="#cite_note-urlanastrozole_(CHEBI:2704)-5">[5]</a></div></li><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;"></div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/CAS%E5%8F%B7" title="CAS号">CAS号</a></th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=120511-73-1">120511-73-1</a>  <img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" />Y</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/PubChem" title="PubChem">PubChem</a> <abbr title="Compound ID">CID</abbr></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/2187">2187</a></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/Guide_to_Pharmacology" title="Guide to Pharmacology">IUPHAR/BPS</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5137">5137</a></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB01217">DB01217</a> <img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" />Y</li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.2102.html">2102</a> <img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" />Y</li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E7%89%B9%E6%AE%8A%E6%88%90%E5%88%86%E6%A8%99%E8%AD%98" title="特殊成分標識">UNII</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/2Z07MYW1AZ">2Z07MYW1AZ</a></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D00960">D00960</a> <img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" />Y</li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:2704">CHEBI:2704</a> <img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" />Y</li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/ChEMBL1399">ChEMBL1399</a> <img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" />Y</li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/w/index.php?title=CompTox%E5%8C%96%E5%AD%A6%E5%93%81%E4%BB%AA%E8%A1%A8%E6%9D%BF&action=edit&redlink=1" class="new" title="CompTox化学品仪表板（页面不存在）">CompTox Dashboard</a>（英语：<a href="https://en.wikipedia.org/wiki/CompTox_Chemicals_Dashboard" class="extiw" title="en:CompTox Chemicals Dashboard">CompTox Chemicals Dashboard</a>） (<abbr title="美国国家环境保护局">EPA</abbr>)</th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID9022607">DTXSID9022607</a> <a href="https://www.wikidata.org/wiki/Q419143#P3117" title="編輯維基數據鏈接"><img alt="編輯維基數據鏈接" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E6%AD%90%E6%B4%B2%E5%8C%96%E5%AD%B8%E5%93%81%E7%AE%A1%E7%90%86%E5%B1%80" title="歐洲化學品管理局">ECHA InfoCard</a></th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.129.723">100.129.723</a> <a href="https://www.wikidata.org/wiki/Q419143#P2566" title="編輯維基數據鏈接"><img alt="編輯維基數據鏈接" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd;">化学信息</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E5%8C%96%E5%AD%A6%E5%BC%8F" title="化学式">化学式</a></th><td class="infobox-data" style="">C17H19N5</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;"><a href="/wiki/%E6%91%A9%E5%B0%94%E8%B4%A8%E9%87%8F" title="摩尔质量">摩尔质量</a></th><td class="infobox-data" style="">293.37 g·mol−1</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;;">3D模型（<a href="/w/index.php?title=JSmol&action=edit&redlink=1" class="new" title="JSmol（页面不存在）">JSmol</a>（英语：<a href="https://en.wikipedia.org/wiki/JSmol" class="extiw" title="en:JSmol">JSmol</a>））</th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"><ul><li><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=N%23CC%28C%29%28C%29c1cc%28Cn2cncn2%29cc%28c1%29C%28C%29%28C%29C%23N">交互式图像</a></li></ul></div></td></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/%E7%AE%80%E5%8C%96%E5%88%86%E5%AD%90%E7%BA%BF%E6%80%A7%E8%BE%93%E5%85%A5%E8%A7%84%E8%8C%83" title="简化分子线性输入规范">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">N#CC(C)(C)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data" style=""><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/%E5%9B%BD%E9%99%85%E5%8C%96%E5%90%88%E7%89%A9%E6%A0%87%E8%AF%86" title="国际化合物标识">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3 <img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" />Y</div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:YBBLVLTVTVSKRW-UHFFFAOYSA-N <img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" />Y</div></li></ul> </div></td></tr></tbody></table> 阿那曲唑（英語：Anastrozole）以商品名Arimidex（安美達錠）等於市面銷售，是一種<a href="/w/index.php?title=%E6%8A%97%E9%9B%8C%E6%BF%80%E7%B4%A0&action=edit&redlink=1" class="new" title="抗雌激素（页面不存在）">抗雌激素</a>（英语：<a href="https://en.wikipedia.org/wiki/Antiestrogen" class="extiw" title="en:Antiestrogen">Antiestrogen</a>）藥物，用於輔助其他治療方法以治療<a href="/wiki/%E4%B9%B3%E7%99%8C" title="乳癌">乳癌</a>。<a href="#cite_note-Label2018-6">[6]</a><a href="#cite_note-AHFS2016-7">[7]</a>特別是用於治療<a href="/w/index.php?title=%E6%BF%80%E7%B4%A0%E5%8F%97%E9%AB%94%E9%99%BD%E6%80%A7%E4%B9%B3%E7%99%8C&action=edit&redlink=1" class="new" title="激素受體陽性乳癌（页面不存在）">激素受體陽性乳癌</a>（英语：<a href="https://en.wikipedia.org/wiki/Hormone_receptor_positive_breast_tumor" class="extiw" title="en:Hormone receptor positive breast tumor">Hormone receptor positive breast tumor</a>）。<a href="#cite_note-AHFS2016-7">[7]</a>它也提供予高風險族群作乳癌預防之用。<a href="#cite_note-AHFS2016-7">[7]</a>此藥物透過<a href="/wiki/%E5%8F%A3%E6%9C%8D%E7%BB%99%E8%8D%AF" title="口服给药">口服</a>方式給藥。<a href="#cite_note-AHFS2016-7">[7]</a> 使用阿那曲唑的常見副作用有<a href="/wiki/%E6%BD%AE%E7%86%B1" title="潮熱">熱潮紅</a>、<a href="/wiki/%E6%83%85%E7%BB%AA%E6%B3%A2%E5%8A%A8" title="情绪波动">情緒波動</a>、<a href="/wiki/%E5%85%B3%E8%8A%82%E7%97%9B" title="关节痛">關節痛</a>和<a href="/wiki/%E5%99%81%E5%BF%83" class="mw-redirect" title="噁心">噁心</a>。<a href="#cite_note-AHFS2016-7">[7]</a><a href="#cite_note-Label2018-6">[6]</a>嚴重的副作用有增加<a href="/wiki/%E5%BF%83%E8%A1%80%E7%AE%A1%E7%96%BE%E7%97%85" title="心血管疾病">心血管疾病</a>和<a href="/wiki/%E9%AA%A8%E8%B3%AA%E7%96%8F%E9%AC%86%E7%97%87" title="骨質疏鬆症">骨質疏鬆症</a>的風險。個體於<a href="/wiki/%E5%A6%8A%E5%A8%A0" title="妊娠">懷孕</a>期間使用可能會傷害胎兒。<a href="#cite_note-AHFS2016-7">[7]</a>阿那曲唑屬於<a href="/w/index.php?title=%E8%8A%B3%E9%A6%99%E5%8C%96%E9%85%B6%E6%8A%91%E5%88%B6%E5%8A%91&action=edit&redlink=1" class="new" title="芳香化酶抑制劑（页面不存在）">芳香化酶抑制劑</a>（英语：<a href="https://en.wikipedia.org/wiki/Aromatase_inhibitor" class="extiw" title="en:Aromatase inhibitor">Aromatase inhibitor</a>）家族，<a href="#cite_note-AHFS2016-7">[7]</a>經由阻止體內<a href="/wiki/%E9%9B%8C%E6%BF%80%E7%B4%A0" title="雌激素">雌激素</a>產生而發揮作用。<a href="#cite_note-AHFS2016-7">[7]</a> 阿那曲唑於1987年於<a href="/wiki/%E8%8B%B1%E5%9C%8B" class="mw-redirect" title="英國">英國</a>取得專利，並於1995年經<a href="/wiki/%E7%BE%8E%E5%9C%8B%E9%A3%9F%E5%93%81%E8%97%A5%E7%89%A9%E7%AE%A1%E7%90%86%E5%B1%80" class="mw-redirect" title="美國食品藥物管理局">美國食品藥物管理局</a>（FDA）核准用作醫療用途。<a href="#cite_note-Fis2006-8">[8]</a><a href="#cite_note-Dukes1997-9">[9]</a>它已被列入<a href="/wiki/%E4%B8%96%E7%95%8C%E8%A1%9B%E7%94%9F%E7%B5%84%E7%B9%94%E5%9F%BA%E6%9C%AC%E8%97%A5%E7%89%A9%E6%A8%99%E6%BA%96%E6%B8%85%E5%96%AE" class="mw-redirect" title="世界衛生組織基本藥物標準清單">世界衛生組織基本藥物標準清單</a>之中。<a href="#cite_note-WHO21st-10">[10]</a>市面上有其<a href="/wiki/%E9%80%9A%E7%94%A8%E5%90%8D%E8%97%A5%E7%89%A9" class="mw-redirect" title="通用名藥物">通用名藥物</a>流通。<a href="#cite_note-AHFS2016-7">[7]</a>此藥物於2021年是美國最常使用<a href="/wiki/%E8%99%95%E6%96%B9%E8%97%A5" title="處方藥">處方藥</a>中排名第182，開立的處方箋數量超過200萬張。<a href="#cite_note-11">[11]</a><a href="#cite_note-12">[12]</a> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="醫療用途">醫療用途</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=1" title="编辑章节：醫療用途">编辑</a>]</div> <div class="mw-heading mw-heading3"><h3 id="乳癌">乳癌</h3>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=2" title="编辑章节：乳癌">编辑</a>]</div> 阿那曲唑用於治療和預防女性乳癌。<a href="#cite_note-AHFS2016-7">[7]</a>在針對原位（早期）乳癌治療的試驗中，患者單獨使用安美達錠（阿那曲唑）或是<a href="/wiki/%E4%BB%96%E8%8E%AB%E6%98%94%E8%8A%AC" title="他莫昔芬">他莫昔芬</a>（<a href="/wiki/%E9%81%B8%E6%93%87%E6%80%A7%E9%9B%8C%E6%BF%80%E7%B4%A0%E5%8F%97%E9%AB%94%E8%AA%BF%E7%AF%80%E7%89%A9" title="選擇性雌激素受體調節物">選擇性雌激素受體調節劑</a>），或是將兩者聯合使用，為期五年，然後再進行五年追蹤。 <a href="#cite_note-ATAC-13">[13]</a>5年多後，接受阿那曲唑治療的組別比接受他莫昔芬治療組別的效果更好。<a href="#cite_note-ATAC-13">[13]</a>此試驗表明阿那曲唑是停經後女性，患有原位激素受體陽性乳癌的的首選治療藥物。<a href="#cite_note-ATAC-13">[13]</a> <div class="mw-heading mw-heading3"><h3 id="性早熟">性早熟</h3>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=3" title="编辑章节：性早熟">编辑</a>]</div> 使用阿那曲唑（每日劑量0.5至1毫克），與<a href="/wiki/%E6%8A%97%E9%9B%84%E6%BF%80%E7%B4%A0" title="抗雄激素">抗雄激素</a><a href="/wiki/%E6%AF%94%E5%8D%A1%E9%AD%AF%E8%83%BA" title="比卡魯胺">比卡魯胺</a>聯合用於男性<a href="/w/index.php?title=%E5%85%92%E7%AB%A5%E6%80%A7%E6%97%A9%E7%86%9F&action=edit&redlink=1" class="new" title="兒童性早熟（页面不存在）">兒童性早熟</a>（英语：<a href="https://en.wikipedia.org/wiki/precocious_puberty" class="extiw" title="en:precocious puberty">precocious puberty</a>）（例如<a href="/w/index.php?title=%E5%AE%B6%E6%97%8F%E6%80%A7%E7%94%B7%E6%80%A7%E9%99%90%E5%88%B6%E6%80%A7%E6%80%A7%E6%97%A9%E7%86%9F&action=edit&redlink=1" class="new" title="家族性男性限制性性早熟（页面不存在）">家族性男性限制性性早熟</a>（英语：<a href="https://en.wikipedia.org/wiki/Familial_male-limited_precocious_puberty" class="extiw" title="en:Familial male-limited precocious puberty">Familial male-limited precocious puberty</a>）（睾酮中毒症（testotoxicosis））和<a href="/w/index.php?title=%E9%A6%AC%E7%A7%91%E6%81%A9-%E4%BA%9E%E7%99%BD%E7%89%B9%E7%97%87%E5%80%99%E7%BE%A4&action=edit&redlink=1" class="new" title="馬科恩-亞白特症候群（页面不存在）">馬科恩-亞白特症候群</a>（英语：<a href="https://en.wikipedia.org/wiki/McCune%E2%80%93Albright_syndrome" class="extiw" title="en:McCune–Albright syndrome">McCune–Albright syndrome</a>））的治療。<a href="#cite_note-FDALabel-14">[14]</a><a href="#cite_note-SchoelwerEugster2015-15">[15]</a><a href="#cite_note-pmid31144045-16">[16]</a><a href="#cite_note-KliegmanStanton2015-17">[17]</a><a href="#cite_note-pmid29292624-18">[18]</a><a href="#cite_note-HaddadEugster2012-19">[19]</a><a href="#cite_note-HaddadEugster2019-20">[20]</a><a href="#cite_note-MisraRadovick2018-21">[21]</a><a href="#cite_note-Mauras2011-22">[22]</a><a href="#cite_note-Fuqua2013-23">[23]</a> <div class="mw-heading mw-heading3"><h3 id="已有配方">已有配方</h3>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=4" title="编辑章节：已有配方">编辑</a>]</div> 目前僅有每片1毫克的口服錠劑。<a href="#cite_note-Label2018-6">[6]</a><a href="#cite_note-WhiteBradnam2015-24">[24]</a>暫無其他配方，或是其他給藥途徑。<a href="#cite_note-WhiteBradnam2015-24">[24]</a> <div class="mw-heading mw-heading2"><h2 id="禁忌症">禁忌症</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=5" title="编辑章节：禁忌症">编辑</a>]</div> 使用阿那曲唑的禁忌症有對此藥物，或是藥物製劑中任何成分過敏、懷孕期間（可能對於胎兒不利）和是進行<a href="/wiki/%E6%AF%8D%E4%B9%B3%E5%93%BA%E8%82%B2" title="母乳哺育">母乳哺育</a>（可能對於嬰兒不利）的個體。<a href="#cite_note-Label2018-6">[6]</a>已觀察到對阿那曲唑的過敏反應有<a href="/wiki/%E9%81%8E%E6%95%8F%E6%80%A7%E4%BC%91%E5%85%8B" class="mw-redirect" title="過敏性休克">過敏性休克</a>、<a href="/wiki/%E8%A1%80%E7%AE%A1%E6%80%A7%E6%B0%B4%E8%82%BF" title="血管性水肿">血管性水腫</a>和<a href="/wiki/%E8%95%81%E9%BA%BB%E7%96%B9" class="mw-redirect" title="蕁麻疹">蕁麻疹</a>。<a href="#cite_note-Label2018-6">[6]</a> <div class="mw-heading mw-heading2"><h2 id="副作用">副作用</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=6" title="编辑章节：副作用">编辑</a>]</div> 使用阿那曲唑的常見副作用（發生率≥10%）有熱潮紅、<a href="/wiki/%E8%99%9B%E5%BC%B1" title="虛弱">虛弱</a>、<a href="/wiki/%E5%85%B3%E8%8A%82%E7%82%8E" title="关节炎">關節炎</a>、<a href="/wiki/%E7%96%BC%E7%97%9B" title="疼痛">疼痛</a>、關節痛、<a href="/wiki/%E9%AB%98%E8%A1%80%E5%A3%93" title="高血壓">高血壓</a>、<a href="/wiki/%E6%86%82%E9%AC%B1" class="mw-redirect" title="憂鬱">憂鬱</a>、噁心和<a href="/wiki/%E5%98%94%E5%90%90" class="mw-redirect" title="嘔吐">嘔吐</a>、皮<a href="/wiki/%E7%96%B9" title="疹">疹</a>、骨質疏鬆症、<a href="/wiki/%E9%AA%A8%E6%8A%98" title="骨折">骨折</a>、<a href="/wiki/%E8%83%8C%E7%97%9B" title="背痛">背痛</a>、<a href="/wiki/%E5%A4%B1%E7%9C%A0" title="失眠">失眠</a>、<a href="/wiki/%E9%A0%AD%E7%97%9B" title="頭痛">頭痛</a>、<a href="/w/index.php?title=%E9%AA%A8%E7%97%9B&action=edit&redlink=1" class="new" title="骨痛（页面不存在）">骨痛</a>（英语：<a href="https://en.wikipedia.org/wiki/bone_pain" class="extiw" title="en:bone pain">bone pain</a>）、<a href="/wiki/%E5%A4%96%E5%91%A8%E6%80%A7%E6%B0%B4%E8%85%AB" title="外周性水腫">外周性水腫</a>、<a href="/wiki/%E5%92%B3%E5%97%BD" title="咳嗽">咳嗽</a>、<a href="/wiki/%E5%91%BC%E5%90%B8%E5%9B%B0%E9%9A%BE" title="呼吸困难">呼吸困難</a>、<a href="/wiki/%E5%92%BD%E7%82%8E" title="咽炎">咽炎</a>和<a href="/wiki/%E6%B7%8B%E5%B7%B4%E6%B0%B4%E8%85%AB" title="淋巴水腫">淋巴水腫</a>。<a href="#cite_note-Label2018-6">[6]</a>嚴重但罕見的不良反應（發生率<0.1%）有<a href="/wiki/%E7%9A%AE%E8%86%9A%E7%97%85" title="皮膚病">皮膚病</a>（如<a href="/wiki/%E7%97%85%E8%AE%8A" class="mw-redirect" title="病變">病變</a>、<a href="/wiki/%E6%BD%B0%E7%98%8D" title="潰瘍">潰瘍</a>或<a href="/wiki/%E6%B0%B4%E7%96%B1" class="mw-redirect" title="水疱">水皰</a>，過敏反應），伴隨臉部、嘴唇、舌頭和/或喉嚨腫脹（可能導致<a href="/wiki/%E5%90%9E%E5%9A%A5" title="吞嚥">吞嚥</a>或<a href="/wiki/%E5%91%BC%E5%90%B8" title="呼吸">呼吸</a>困難），以及肝指數異常與<a href="/wiki/%E8%82%9D%E7%82%8E" title="肝炎">肝炎</a>。<a href="#cite_note-Label2018-6">[6]</a> <div class="mw-heading mw-heading2"><h2 id="與其他藥物交互作用">與其他藥物交互作用</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=7" title="编辑章节：與其他藥物交互作用">编辑</a>]</div> 阿那曲唑被認為對<a href="/wiki/%E7%BB%86%E8%83%9E%E8%89%B2%E7%B4%A0P450" title="细胞色素P450">細胞色素P450</a>中的酵素 - <a href="/wiki/CYP1A2" title="CYP1A2">CYP1A2</a>、<a href="/w/index.php?title=CYP2A6&action=edit&redlink=1" class="new" title="CYP2A6（页面不存在）">CYP2A6</a>（英语：<a href="https://en.wikipedia.org/wiki/CYP2A6" class="extiw" title="en:CYP2A6">CYP2A6</a>）、<a href="/wiki/CYP2D6" title="CYP2D6">CYP2D6</a>、<a href="/w/index.php?title=CYP2C8&action=edit&redlink=1" class="new" title="CYP2C8（页面不存在）">CYP2C8</a>（英语：<a href="https://en.wikipedia.org/wiki/CYP2C8" class="extiw" title="en:CYP2C8">CYP2C8</a>）、<a href="/wiki/CYP2C9" title="CYP2C9">CYP2C9</a>和<a href="/wiki/CYP2C19" title="CYP2C19">CYP2C19</a>具有臨床上可忽略不計的抑制作用。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a><a href="#cite_note-Label2018-6">[6]</a>因此人們認為阿那曲唑與細胞色素P450<a href="/wiki/%E5%8F%97%E8%B3%AA" class="mw-redirect" title="受質">受質</a>不太可能發生藥物交互作用。<a href="#cite_note-SanfordPlosker2008-4">[4]</a>迄2003年，尚無臨床上顯著的藥物交互作用報告出現。<a href="#cite_note-Lonning2003-3">[3]</a> 阿那曲唑不影響他莫昔芬或他莫昔芬主要代謝物N-去甲基他莫昔芬的體內循環濃度。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a>已發現他莫昔芬會導致阿那曲唑的<a href="/wiki/%E6%9B%B2%E7%BA%BF%E4%B8%8B%E9%9D%A2%E7%A7%AF_(%E8%8D%AF%E7%89%A9%E4%BB%A3%E8%B0%A2%E5%8A%A8%E5%8A%9B%E5%AD%A6)" title="曲线下面积 (药物代谢动力学)">曲線下面積</a> (AUC) 降低27%。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a>但與單獨使用阿那曲唑組相比，同時接受阿那曲唑和他莫昔芬治療組的<a href="/wiki/%E9%9B%8C%E4%BA%8C%E9%86%87" title="雌二醇">雌二醇</a>水平無顯著差異，因此阿那曲唑水平下降不被認為具有臨床重要性。<a href="#cite_note-SanfordPlosker2008-4">[4]</a> <div class="mw-heading mw-heading2"><h2 id="藥理學">藥理學</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=8" title="编辑章节：藥理學">编辑</a>]</div> <div class="mw-heading mw-heading3"><h3 id="藥效學">藥效學</h3>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=9" title="编辑章节：藥效學">编辑</a>]</div> 阿那曲唑透過與<a href="/wiki/%E8%8A%B3%E9%A6%99%E5%8C%96%E9%85%B6" title="芳香化酶">芳香化酶</a>可逆結合而發揮作用，並透過<a href="/wiki/%E7%AB%B6%E7%88%AD%E6%80%A7%E6%8A%91%E5%88%B6%E5%8A%91" title="競爭性抑制劑">競爭性抑制劑</a>來阻止週邊組織中<a href="/wiki/%E9%9B%84%E6%BF%80%E7%B4%A0" title="雄激素">雄激素</a>向雌激素轉化。<a href="#cite_note-pmid14623515-25">[25]</a>研究發現每天攝取1毫克的劑量，可達到96.7%至97.3%的芳香化酶抑制，每天攝取10毫克的劑量可達到98.1%的芳香化酶抑制。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a>因此每天1毫克被認為是此藥物實現最大程度抑制芳香化酶所需的最小劑量。<a href="#cite_note-Lonning2003-3">[3]</a>芳香化酶活性降低導致停經後女性雌二醇水平至少降低85%。<a href="#cite_note-Lonning2003-3">[3]</a><a href="/wiki/%E7%9A%AE%E8%B3%AA%E9%A1%9E%E5%9B%BA%E9%86%87" title="皮質類固醇">皮質類固醇</a>和其他<a href="/w/index.php?title=%E8%85%8E%E4%B8%8A%E8%85%BA%E9%A1%9E%E5%9B%BA%E9%86%87&action=edit&redlink=1" class="new" title="腎上腺類固醇（页面不存在）">腎上腺類固醇</a>（英语：<a href="https://en.wikipedia.org/wiki/Adrenal_steroid" class="extiw" title="en:Adrenal steroid">Adrenal steroid</a>）的濃度不受阿那曲唑的影響。<a href="#cite_note-Lonning2003-3">[3]</a> <div class="mw-heading mw-heading3"><h3 id="藥物動力學">藥物動力學</h3>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=10" title="编辑章节：藥物動力學">编辑</a>]</div> 目前對阿那曲唑在人體中的<a href="/wiki/%E7%94%9F%E7%89%A9%E5%88%A9%E7%94%A8%E5%BA%A6" title="生物利用度">生物利用度</a>尚不清楚，但發現它在動物體內吸收良好。<a href="#cite_note-Lønning2003-2">[2]</a><a href="#cite_note-Label2018-6">[6]</a>在人類體內，阿那曲唑的吸收在1到20毫克/天的劑量範圍內呈線性變化，且不會因重複給藥而改變。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a><a href="#cite_note-Label2018-6">[6]</a>服藥時飲食不會顯著影響藥物的吸收。<a href="#cite_note-SanfordPlosker2008-4">[4]</a><a href="#cite_note-Label2018-6">[6]</a>阿那曲唑的<a href="/wiki/%E6%9C%80%E5%A4%A7%E8%A1%80%E8%8D%AF%E6%B5%93%E5%BA%A6" title="最大血药浓度">最大血藥濃度</a>出現在給藥後平均約3小時（範圍在2至12小時之間）。<a href="#cite_note-SanfordPlosker2008-4">[4]</a><a href="#cite_note-Label2018-6">[6]</a>連續給藥7至10天內可達<a href="/wiki/%E7%A9%A9%E6%85%8B_(%E7%B3%BB%E7%B5%B1)" title="穩態 (系統)">穩態</a>水平，累積濃度比剛開始服用時增加3.5倍。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a>然而，對雌二醇的最大抑制發生在用藥後後3或4天內。<a href="#cite_note-Lonning2003-3">[3]</a> 對<a href="/wiki/%E5%9A%99%E9%BD%92%E7%9B%AE" class="mw-redirect" title="嚙齒目">嚙齒目</a>動物的研究發現由於在其<a href="/wiki/%E8%A1%80%E8%85%A6%E5%B1%8F%E9%9A%9C" title="血腦屏障">血腦屏障</a>中<a href="/w/index.php?title=P-%E7%B3%96%E8%9B%8B%E7%99%BD&action=edit&redlink=1" class="new" title="P-糖蛋白（页面不存在）">P-糖蛋白</a>（英语：<a href="https://en.wikipedia.org/wiki/P-glycoprotein" class="extiw" title="en:P-glycoprotein">P-glycoprotein</a>）的<a href="/w/index.php?title=%E5%A4%96%E6%8E%92%E6%B3%B5&action=edit&redlink=1" class="new" title="外排泵（页面不存在）">外排泵</a>（英语：<a href="https://en.wikipedia.org/wiki/efflux_pump" class="extiw" title="en:efflux pump">efflux pump</a>）作用，讓阿那曲唑難以穿透而對<a href="/wiki/%E4%B8%AD%E6%A8%9E%E7%A5%9E%E7%B6%93%E7%B3%BB%E7%B5%B1" title="中樞神經系統">中樞神經系統</a>發揮作用，而對同樣是芳香化酶抑制劑的<a href="/wiki/%E4%BE%86%E6%9B%B2%E5%94%91" title="來曲唑">來曲唑</a>和<a href="/w/index.php?title=%E6%B2%83%E5%88%A9%E5%94%91&action=edit&redlink=1" class="new" title="沃利唑（页面不存在）">沃利唑</a>（英语：<a href="https://en.wikipedia.org/wiki/Vorozole" class="extiw" title="en:Vorozole">Vorozole</a>），情況則非如此。<a href="#cite_note-CostaCarneiro2016-26">[26]</a><a href="#cite_note-RussellCheung2017-27">[27]</a><a href="#cite_note-MiyajimaKusuhara2013-28">[28]</a>阿那曲唑可能對人類具有周邊神經選擇性（主要作用機制在於中樞神經系統之外），但這一點尚未得到證實。<a href="#cite_note-MiyajimaKusuhara2013-28">[28]</a>但雌二醇是周邊合成，很容易穿過血腦屏障，因此阿那曲唑仍有可能在一定程度上降低中樞神經系統中的雌二醇水平。阿那曲唑的<a href="/wiki/%E8%A1%80%E6%B5%86%E8%9B%8B%E7%99%BD%E7%BB%93%E5%90%88" title="血浆蛋白结合">血漿蛋白結合</a>率為40%。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a> 阿那曲唑的代謝是透過<a href="/wiki/%E7%83%B7%E5%9F%BA%E5%8C%96" title="烷基化">烷基化</a>、<a href="/wiki/%E7%BE%9F%E5%9F%BA%E5%8C%96" title="羟基化">羥基化</a>和<a href="/w/index.php?title=%E8%91%A1%E8%90%84%E9%86%A3%E9%86%9B%E9%85%B8%E5%8C%96&action=edit&redlink=1" class="new" title="葡萄醣醛酸化（页面不存在）">葡萄醣醛酸化</a>（英语：<a href="https://en.wikipedia.org/wiki/Glucuronidation" class="extiw" title="en:Glucuronidation">Glucuronidation</a>）進行。<a href="#cite_note-Lonning2003-3">[3]</a>其主要代謝物並無活性，而是由阿那曲唑本身對芳香化酶產生抑制作用。<a href="#cite_note-Label2018-6">[6]</a>阿那曲唑在人體的<a href="/wiki/%E7%94%9F%E7%89%A9%E5%8D%8A%E8%A1%B0%E6%9C%9F" title="生物半衰期">生物半衰期</a>為40至50小時（1.7至2.1天），<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a>因此可每日只給藥一次。<a href="#cite_note-SanfordPlosker2008-4">[4]</a>藥物主要經由<a href="/wiki/%E8%82%9D%E8%87%9F" title="肝臟">肝臟</a>排除（83%至85%），但也少量經由<a href="/wiki/%E8%85%8E" title="腎">腎</a>臟排除（11%）。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-Lønning2003-2">[2]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a>阿那曲唑主要經由<a href="/wiki/%E5%B0%BF" title="尿">尿</a>液排出人體，有少量經由<a href="/wiki/%E7%B3%9E%E4%BE%BF" title="糞便">糞便</a>排泄。<a href="#cite_note-SanfordPlosker2008-4">[4]</a> <div class="mw-heading mw-heading2"><h2 id="化學">化學</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=11" title="编辑章节：化學">编辑</a>]</div> 阿那曲唑是一種非類固醇<a href="/wiki/%E8%8B%84%E5%9F%BA" title="苄基">苄基</a><a href="/wiki/%E4%B8%89%E5%94%91" title="三唑">三唑</a>。<a href="#cite_note-Lonning2003-3">[3]</a><a href="#cite_note-SanfordPlosker2008-4">[4]</a>又稱α,α,α',α'-四甲基-5-(1H-1,2,4-三唑-1-基甲基)-間苯二乙腈。阿那曲唑在結構上與來曲唑、<a href="/w/index.php?title=%E6%B3%95%E5%B1%88%E5%94%91&action=edit&redlink=1" class="new" title="法屈唑（页面不存在）">法屈唑</a>（英语：<a href="https://en.wikipedia.org/wiki/fadrozole" class="extiw" title="en:fadrozole">fadrozole</a>）和沃利唑相似，均屬於唑類藥物。<a href="#cite_note-Thurston2006-29">[29]</a><a href="#cite_note-Kunal2015-30">[30]</a><a href="#cite_note-SmithAllerton2012-31">[31]</a><a href="#cite_note-32">[32]</a> <div class="mw-heading mw-heading2"><h2 id="歷史">歷史</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=12" title="编辑章节：歷史">编辑</a>]</div> 英國<a href="/wiki/%E5%B8%9D%E5%9B%BD%E5%8C%96%E5%AD%A6%E5%B7%A5%E4%B8%9A" title="帝国化学工业">帝國化學工業</a>公司 (ICI)於1987年取得阿那曲唑的專利，此藥物於1995年被批准用於醫療用途，特別是在治療乳癌。<a href="#cite_note-Fis2006-8">[8]</a><a href="#cite_note-Dukes1997-9">[9]</a> <div class="mw-heading mw-heading2"><h2 id="社會與文化">社會與文化</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=13" title="编辑章节：社會與文化">编辑</a>]</div> <div class="mw-heading mw-heading3"><h3 id="通用名稱">通用名稱</h3>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=14" title="编辑章节：通用名稱">编辑</a>]</div> 阿那曲唑是通用名藥物名稱，在<a href="/wiki/%E5%9B%BD%E9%99%85%E9%9D%9E%E4%B8%93%E6%9C%89%E8%8D%AF%E5%90%8D" title="国际非专有药名">國際非專有藥名</a>（INN）、<a href="/wiki/%E7%BE%8E%E5%9B%BD%E9%87%87%E7%94%A8%E5%90%8D%E7%A7%B0" title="美国采用名称">美國採用名稱</a>（USAN）、<a href="/w/index.php?title=%E8%8B%B1%E5%9C%8B%E6%A0%B8%E5%87%86%E5%90%8D%E7%A8%B1&action=edit&redlink=1" class="new" title="英國核准名稱（页面不存在）">英國核准名稱</a>（英语：<a href="https://en.wikipedia.org/wiki/British_Approved_Name" class="extiw" title="en:British Approved Name">British Approved Name</a>）（BAN）及<a href="/w/index.php?title=%E6%97%A5%E6%9C%AC%E6%A0%B8%E5%87%86%E5%90%8D%E7%A8%B1&action=edit&redlink=1" class="new" title="日本核准名稱（页面不存在）">日本核准名稱</a>（英语：<a href="https://en.wikipedia.org/wiki/Japanese_Accepted_Name" class="extiw" title="en:Japanese Accepted Name">Japanese Accepted Name</a>）（JAN）均使用相同名稱。<a href="#cite_note-Drugs.com-1">[1]</a> <div class="mw-heading mw-heading3"><h3 id="品牌名稱">品牌名稱</h3>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=15" title="编辑章节：品牌名稱">编辑</a>]</div> 阿那曲唑主要以Arimidex品牌銷售。<a href="#cite_note-Drugs.com-1">[1]</a>也以各種品牌名稱在世界各地銷售。<a href="#cite_note-Drugs.com-1">[1]</a> <div class="mw-heading mw-heading3"><h3 id="取得">取得</h3>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=16" title="编辑章节：取得">编辑</a>]</div> 阿那曲唑可在世界各地取得。<a href="#cite_note-Drugs.com-1">[1]</a> <div class="mw-heading mw-heading2"><h2 id="研究">研究</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=17" title="编辑章节：研究">编辑</a>]</div> 阿那曲唑與他莫昔芬等選擇性雌激素受體調節劑相比，在治療<a href="/wiki/%E7%94%B7%E6%80%A7%E4%B9%B3%E8%85%BA%E5%8F%91%E8%82%B2" title="男性乳腺发育">男性乳房發育症</a>方面效果不佳。<a href="#cite_note-SungFagerlund2015-33">[33]</a><a href="#cite_note-BedognettiRubagotti2010-34">[34]</a> 阿那曲唑正被開發用於治療<a href="/wiki/%E5%A5%B3%E6%80%A7%E4%B8%8D%E5%AD%95%E7%97%87" title="女性不孕症">女性不孕症</a>，但尚未完成研究，也尚未被批准用於此適應症。<a href="#cite_note-AdisInsight-1-35">[35]</a> 阿那曲唑和<a href="/wiki/%E5%B7%A6%E7%82%94%E8%AF%BA%E5%AD%95%E9%85%AE" title="左炔诺孕酮">左炔諾孕酮</a>陰道避孕環（開發代號BAY 98-7196）被開發用作激素避孕藥，和治療<a href="/wiki/%E5%AD%90%E5%AE%AE%E5%85%A7%E8%86%9C%E7%95%B0%E4%BD%8D%E7%97%87" title="子宮內膜異位症">子宮內膜異位症</a>，但開發工作於2018年11月停止，配方從未上市。<a href="#cite_note-AdisInsight-2-36">[36]</a> 阿那曲唑可增加男性<a href="/wiki/%E7%9D%AA%E9%85%AE" class="mw-redirect" title="睪酮">睪酮</a>水平，並已被研究作為有<a href="/wiki/%E6%80%A7%E8%85%BA%E5%8A%9F%E8%83%BD%E4%BD%8E%E4%B8%8B%E7%97%87" title="性腺功能低下症">性腺功能低下症</a>的男性作<a href="/wiki/%E9%9B%84%E6%BF%80%E7%B4%A0%E6%9B%BF%E4%BB%A3%E7%96%97%E6%B3%95" title="雄激素替代疗法">雄激素替代療法</a>之用。<a href="#cite_note-SerefogluGokce2013-37">[37]</a><a href="#cite_note-KheraAdaikan2016-38">[38]</a>然而人們擔心此藥物對該患者群體的骨礦物質密度以及其他副作用的長期影響。<a href="#cite_note-SerefogluGokce2013-37">[37]</a> <div class="mw-heading mw-heading2"><h2 id="參考文獻">參考文獻</h2>[<a href="/w/index.php?title=%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&action=edit&section=18" title="编辑章节：參考文獻">编辑</a>]</div> <div class="reflist columns references-column-count references-column-count-2" style="-moz-column-count: 2; -webkit-column-count: 2; column-count: 2; list-style-type: decimal;"> <ol class="references"> <li id="cite_note-Drugs.com-1">^ <a href="#cite_ref-Drugs.com_1-0">1.0</a> <a href="#cite_ref-Drugs.com_1-1">1.1</a> <a href="#cite_ref-Drugs.com_1-2">1.2</a> <a href="#cite_ref-Drugs.com_1-3">1.3</a> <a href="#cite_ref-Drugs.com_1-4">1.4</a> <cite class="citation web"><a rel="nofollow" class="external text" href="https://www.drugs.com/international/anastrozole.html">Anastrozole</a>.</cite><span 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June 2019, 33 (3): 101273. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/31027974">PMID 31027974</a>. <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:135410503">S2CID 135410503</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.beem.2019.04.007">doi:10.1016/j.beem.2019.04.007</a>. <a rel="nofollow" class="external text" href="//hdl.handle.net/1805%2F19111">hdl:1805/19111</a> <img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" />.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Peripheral+precocious+puberty+including+congenital+adrenal+hyperplasia%3A+causes%2C+consequences%2C+management+and+outcomes&rft.au=Eugster%2C+EA&rft.aufirst=NG&rft.aulast=Haddad&rft.date=2019-06&rft.genre=article&rft.issue=3&rft.jtitle=Best+Practice+%26+Research.+Clinical+Endocrinology+%26+Metabolism&rft.pages=101273&rft.volume=33&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A135410503&rft_id=info%3Adoi%2F10.1016%2Fj.beem.2019.04.007&rft_id=info%3Ahdl%2F1805%2F19111&rft_id=info%3Apmid%2F31027974&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988">  </li> <li id="cite_note-MisraRadovick2018-21"><a href="#cite_ref-MisraRadovick2018_21-0">^</a> <cite class="citation book">Misra M, Radovick S. 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Springer. 2018: 589–615. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-3-319-73781-2" title="Special:网络书源/978-3-319-73781-2">ISBN 978-3-319-73781-2</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1007%2F978-3-319-73782-9_26">doi:10.1007/978-3-319-73782-9_26</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Precocious+Puberty&rft.au=Radovick%2C+S&rft.aufirst=M&rft.aulast=Misra&rft.btitle=Pediatric+Endocrinology&rft.date=2018&rft.genre=bookitem&rft.isbn=978-3-319-73781-2&rft.pages=589-615&rft.pub=Springer&rft_id=info%3Adoi%2F10.1007%2F978-3-319-73782-9_26&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988">  </li> <li id="cite_note-Mauras2011-22"><a href="#cite_ref-Mauras2011_22-0">^</a> <cite class="citation journal">Mauras N. <a rel="nofollow" class="external text" href="https://archive.org/details/sim_pediatric-clinics-of-north-america_2011-10_58_5/page/1167">Strategies for maximizing growth in puberty in children with short stature</a>. Pediatric Clinics of North America. October 2011, 58 (5): 1167–79, x. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/21981954">PMID 21981954</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.pcl.2011.07.007">doi:10.1016/j.pcl.2011.07.007</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Strategies+for+maximizing+growth+in+puberty+in+children+with+short+stature&rft.aufirst=N&rft.aulast=Mauras&rft.date=2011-10&rft.genre=article&rft.issue=5&rft.jtitle=Pediatric+Clinics+of+North+America&rft.pages=1167-79%2C+x&rft.volume=58&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_pediatric-clinics-of-north-america_2011-10_58_5%2Fpage%2F1167&rft_id=info%3Adoi%2F10.1016%2Fj.pcl.2011.07.007&rft_id=info%3Apmid%2F21981954&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988">  </li> <li id="cite_note-Fuqua2013-23"><a href="#cite_ref-Fuqua2013_23-0">^</a> <cite class="citation journal">Fuqua JS. 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June 2013, 98 (6): 2198–2207. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/23515450">PMID 23515450</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fjc.2013-1024">doi:10.1210/jc.2013-1024</a> <img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" />.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Treatment+and+outcomes+of+precocious+puberty%3A+an+update&rft.aufirst=JS&rft.aulast=Fuqua&rft.date=2013-06&rft.genre=article&rft.issue=6&rft.jtitle=The+Journal+of+Clinical+Endocrinology+and+Metabolism&rft.pages=2198-2207&rft.volume=98&rft_id=info%3Adoi%2F10.1210%2Fjc.2013-1024&rft_id=info%3Apmid%2F23515450&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988">  </li> <li id="cite_note-WhiteBradnam2015-24">^ <a href="#cite_ref-WhiteBradnam2015_24-0">24.0</a> <a href="#cite_ref-WhiteBradnam2015_24-1">24.1</a> <cite class="citation book">White R, Bradnam V. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=yyikBwAAQBAJ&pg=PA108">Handbook of Drug Administration via Enteral Feeding Tubes, 3rd edition</a>. Pharmaceutical Press. 11 March 2015: 108–. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-0-85711-162-3" title="Special:网络书源/978-0-85711-162-3">ISBN 978-0-85711-162-3</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.au=Bradnam%2C+V&rft.aufirst=R&rft.aulast=White&rft.btitle=Handbook+of+Drug+Administration+via+Enteral+Feeding+Tubes%2C+3rd+edition&rft.date=2015-03-11&rft.genre=book&rft.isbn=978-0-85711-162-3&rft.pages=108-&rft.pub=Pharmaceutical+Press&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DyyikBwAAQBAJ%26pg%3DPA108&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988">  </li> <li id="cite_note-pmid14623515-25"><a href="#cite_ref-pmid14623515_25-0">^</a> <cite class="citation journal">Simpson ER. Sources of estrogen and their importance. The Journal of Steroid Biochemistry and Molecular Biology. September 2003, 86 (3–5): 225–230. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/14623515">PMID 14623515</a>. <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:11210435">S2CID 11210435</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0960-0760%2803%2900360-1">doi:10.1016/S0960-0760(03)00360-1</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Sources+of+estrogen+and+their+importance&rft.aufirst=ER&rft.aulast=Simpson&rft.date=2003-09&rft.genre=article&rft.issue=3%E2%80%935&rft.jtitle=The+Journal+of+Steroid+Biochemistry+and+Molecular+Biology&rft.pages=225-230&rft.volume=86&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A11210435&rft_id=info%3Adoi%2F10.1016%2FS0960-0760%2803%2900360-1&rft_id=info%3Apmid%2F14623515&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988">  </li> <li id="cite_note-CostaCarneiro2016-26"><a href="#cite_ref-CostaCarneiro2016_26-0">^</a> <cite class="citation journal">Costa R, Carneiro BA, Wainwright DA, Santa-Maria CA, Kumthekar P, Chae YK, Gradishar WJ, Cristofanilli M, Giles FJ. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC7360139">Developmental therapeutics for patients with breast cancer and central nervous system metastasis: current landscape and future perspectives</a>. 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January 2017, 28 (1): 44–56. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC7360139">PMC 7360139</a> <img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" />. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/28177431">PMID 28177431</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fannonc%2Fmdw532">doi:10.1093/annonc/mdw532</a> <img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" />.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Developmental+therapeutics+for+patients+with+breast+cancer+and+central+nervous+system+metastasis%3A+current+landscape+and+future+perspectives&rft.au=Carneiro%2C+BA&rft.au=Chae%2C+YK&rft.au=Cristofanilli%2C+M&rft.au=Giles%2C+FJ&rft.au=Gradishar%2C+WJ&rft.au=Kumthekar%2C+P&rft.au=Santa-Maria%2C+CA&rft.au=Wainwright%2C+DA&rft.aufirst=R&rft.aulast=Costa&rft.date=2017-01&rft.genre=article&rft.issue=1&rft.jtitle=Annals+of+Oncology&rft.pages=44-56&rft.volume=28&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC7360139&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC7360139&rft_id=info%3Adoi%2F10.1093%2Fannonc%2Fmdw532&rft_id=info%3Apmid%2F28177431&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988">  </li> <li id="cite_note-RussellCheung2017-27"><a href="#cite_ref-RussellCheung2017_27-0">^</a> <cite class="citation journal">Russell N, Cheung A, Grossmann M. 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August 2017, 24 (8): R297–R313. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/28667081">PMID 28667081</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1530%2FERC-17-0153">doi:10.1530/ERC-17-0153</a> <img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" />.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Estradiol+for+the+mitigation+of+adverse+effects+of+androgen+deprivation+therapy&rft.au=Cheung%2C+A&rft.au=Grossmann%2C+M&rft.aufirst=N&rft.aulast=Russell&rft.date=2017-08&rft.genre=article&rft.issue=8&rft.jtitle=Endocrine-Related+Cancer&rft.pages=R297-R313&rft.volume=24&rft_id=info%3Adoi%2F10.1530%2FERC-17-0153&rft_id=info%3Apmid%2F28667081&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988">  </li> <li id="cite_note-MiyajimaKusuhara2013-28">^ <a href="#cite_ref-MiyajimaKusuhara2013_28-0">28.0</a> <a href="#cite_ref-MiyajimaKusuhara2013_28-1">28.1</a> <cite class="citation journal">Miyajima M, Kusuhara H, Takahashi K, Takashima T, Hosoya T, Watanabe Y, Sugiyama Y. Investigation of the effect of active efflux at the blood-brain barrier on the distribution of nonsteroidal aromatase inhibitors in the central nervous system. Journal of Pharmaceutical Sciences. September 2013, 102 (9): 3309–3319. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/23712697">PMID 23712697</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fjps.23600">doi:10.1002/jps.23600</a> <img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" />.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Investigation+of+the+effect+of+active+efflux+at+the+blood-brain+barrier+on+the+distribution+of+nonsteroidal+aromatase+inhibitors+in+the+central+nervous+system&rft.au=Hosoya%2C+T&rft.au=Kusuhara%2C+H&rft.au=Sugiyama%2C+Y&rft.au=Takahashi%2C+K&rft.au=Takashima%2C+T&rft.au=Watanabe%2C+Y&rft.aufirst=M&rft.aulast=Miyajima&rft.date=2013-09&rft.genre=article&rft.issue=9&rft.jtitle=Journal+of+Pharmaceutical+Sciences&rft.pages=3309-3319&rft.volume=102&rft_id=info%3Adoi%2F10.1002%2Fjps.23600&rft_id=info%3Apmid%2F23712697&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988">  </li> <li id="cite_note-Thurston2006-29"><a href="#cite_ref-Thurston2006_29-0">^</a> <cite class="citation book">Thurston DE. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=6mPLBQAAQBAJ&pg=PA136">Chemistry and Pharmacology of Anticancer Drugs</a>. CRC Press. 2006-11-22: 136–. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-1-4200-0890-6" title="Special:网络书源/978-1-4200-0890-6">ISBN 978-1-4200-0890-6</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.aufirst=DE&rft.aulast=Thurston&rft.btitle=Chemistry+and+Pharmacology+of+Anticancer+Drugs&rft.date=2006-11-22&rft.genre=book&rft.isbn=978-1-4200-0890-6&rft.pages=136-&rft.pub=CRC+Press&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D6mPLBQAAQBAJ%26pg%3DPA136&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988">  </li> <li id="cite_note-Kunal2015-30"><a href="#cite_ref-Kunal2015_30-0">^</a> <cite class="citation book">Roy, Kunal. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=z-yfBwAAQBAJ&pg=PA437">Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment</a>. IGI Global. 2015-02-28: 437–. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-1-4666-8137-8" title="Special:网络书源/978-1-4666-8137-8">ISBN 978-1-4666-8137-8</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.au=Roy%2C+Kunal&rft.btitle=Quantitative+Structure-Activity+Relationships+in+Drug+Design%2C+Predictive+Toxicology%2C+and+Risk+Assessment&rft.date=2015-02-28&rft.genre=book&rft.isbn=978-1-4666-8137-8&rft.pages=437-&rft.pub=IGI+Global&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3Dz-yfBwAAQBAJ%26pg%3DPA437&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988">  </li> <li id="cite_note-SmithAllerton2012-31"><a href="#cite_ref-SmithAllerton2012_31-0">^</a> <cite class="citation book">Smith DA, Allerton C, Kalgutkar AS, van de Waterbeemd H, Walker DK. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=tz6khNt2wSYC&pg=PA197">Pharmacokinetics and Metabolism in Drug Design</a>. John Wiley & Sons. 2012-09-13: 197–. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/978-3-527-64529-9" title="Special:网络书源/978-3-527-64529-9">ISBN 978-3-527-64529-9</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.au=Allerton%2C+C&rft.au=Kalgutkar%2C+AS&rft.au=Walker%2C+DK&rft.au=van+de+Waterbeemd%2C+H&rft.aufirst=DA&rft.aulast=Smith&rft.btitle=Pharmacokinetics+and+Metabolism+in+Drug+Design&rft.date=2012-09-13&rft.genre=book&rft.isbn=978-3-527-64529-9&rft.pages=197-&rft.pub=John+Wiley+%26+Sons&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3Dtz6khNt2wSYC%26pg%3DPA197&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988">  </li> <li id="cite_note-32"><a href="#cite_ref-32">^</a> <cite class="citation book"><a rel="nofollow" class="external text" href="https://books.google.com/books?id=HjL1IgWzy1gC">Environmental Health Perspectives: Supplements</a>. 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PLOS ONE. 2015, 10 (8): e0136094. <a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2015PLoSO..1036094F">Bibcode:2015PLoSO..1036094F</a>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC4550398">PMC 4550398</a> <img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" />. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/26308532">PMID 26308532</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.pone.0136094">doi:10.1371/journal.pone.0136094</a> <img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" />.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%98%BF%E9%82%A3%E6%9B%B2%E5%94%91&rft.atitle=Gynecomastia+in+Patients+with+Prostate+Cancer%3A+A+Systematic+Review&rft.au=Cormio%2C+L&rft.au=Elander%2C+A&rft.au=Lewin%2C+R&rft.au=Palangi%2C+L&rft.au=Santanelli+di+Pompeo%2C+F&rft.au=Selvaggi%2C+G&rft.aufirst=A&rft.aulast=Fagerlund&rft.date=2015&rft.genre=article&rft.issue=8&rft.jtitle=PLOS+ONE&rft.pages=e0136094&rft.volume=10&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4550398&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4550398&rft_id=info%3Abibcode%2F2015PLoSO..1036094F&rft_id=info%3Adoi%2F10.1371%2Fjournal.pone.0136094&rft_id=info%3Apmid%2F26308532&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988">  </li> <li id="cite_note-BedognettiRubagotti2010-34"><a href="#cite_ref-BedognettiRubagotti2010_34-0">^</a> <cite class="citation journal">Bedognetti D, Rubagotti A, Zoppoli G, Boccardo F. 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Diagnosis and Treatment of Testosterone Deficiency: Recommendations From the Fourth International Consultation for Sexual Medicine (ICSM 2015). The Journal of Sexual Medicine. December 2016, 13 (12): 1787–1804. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/27914560">PMID 27914560</a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.jsxm.2016.10.009">doi:10.1016/j.jsxm.2016.10.009</a>.</cite><span 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class="new" title="抗雌激素（页面不存在）">抗雌激素类</a>（英语：<a href="https://en.wikipedia.org/wiki/antiestrogen" class="extiw" title="en:antiestrogen">antiestrogen</a>）</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/wiki/%E9%9B%8C%E6%BF%80%E7%B4%A0" title="雌激素">雌激素</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px;background:#DDDDFF;"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:10em;;text-align:center;"><a href="/w/index.php?title=Estrogen_receptor&action=edit&redlink=1" class="new" title="Estrogen receptor（页面不存在）"><abbr title="Estrogen receptor">ER</abbr></a>（<a href="/w/index.php?title=%E9%9B%8C%E6%BF%80%E7%B4%A0%E5%8F%97%E9%AB%94&action=edit&redlink=1" class="new" title="雌激素受體（页面不存在）">雌激素受體</a>（英语：<a href="https://en.wikipedia.org/wiki/Estrogen_receptor" class="extiw" title="en:Estrogen receptor">Estrogen receptor</a>）） 激動劑</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0px"><div style="padding:0em 0.25em"> <ol><li>（<a href="/wiki/%E7%94%BE%E9%AB%94" class="mw-redirect" title="甾體">甾體</a>類） <a href="/w/index.php?title=Alfatradiol&action=edit&redlink=1" class="new" title="Alfatradiol（页面不存在）">Alfatradiol</a></li> <li>某些<a href="/wiki/%E9%9B%84%E6%BF%80%E7%B4%A0" title="雄激素">雄激素</a>/<a href="/w/index.php?title=%E5%90%88%E6%88%90%E7%B1%BB%E5%9B%BA%E9%86%87&action=edit&redlink=1" class="new" title="合成类固醇（页面不存在）">合成类固醇</a>(e.g., <a href="/w/index.php?title=Testosterone_(medication)&action=edit&redlink=1" class="new" title="Testosterone (medication)（页面不存在）">testosterone</a>, <a href="/w/index.php?title=List_of_androgen_esters&action=edit&redlink=1" class="new" title="List of androgen esters（页面不存在）">testosterone ester</a>s, <a href="/w/index.php?title=Methyltestosterone&action=edit&redlink=1" class="new" title="Methyltestosterone（页面不存在）">methyltestosterone</a>, <a href="/w/index.php?title=Metandienone&action=edit&redlink=1" class="new" title="Metandienone（页面不存在）">metandienone</a>, <a href="/w/index.php?title=List_of_androgen_esters&action=edit&redlink=1" class="new" title="List of androgen esters（页面不存在）">nandrolone esters</a>) (via estrogenic metabolites)</li> <li>某些<a href="/wiki/%E9%BB%84%E4%BD%93%E5%88%B6%E5%89%82" title="黄体制剂">黃體製劑</a> (例如：<a href="/w/index.php?title=%E8%AB%BE%E7%91%9E%E9%85%AE&action=edit&redlink=1" class="new" title="諾瑞酮（页面不存在）">諾瑞酮</a>（英语：<a href="https://en.wikipedia.org/wiki/Noretynodrel" class="extiw" title="en:Noretynodrel">Noretynodrel</a>），<a href="/w/index.php?title=%E5%B7%A6%E7%82%94%E8%AF%BA%E5%AD%95%E9%85%AE%E4%BA%8C%E9%86%8B%E9%85%B8%E9%85%AF&action=edit&redlink=1" class="new" title="左炔诺孕酮二醋酸酯（页面不存在）">左炔诺孕酮二醋酸酯</a>（英语：<a href="https://en.wikipedia.org/wiki/Etynodiol_diacetate" class="extiw" title="en:Etynodiol diacetate">Etynodiol diacetate</a>），<a href="/w/index.php?title=%E6%9B%BF%E5%89%8D%E5%88%97%E9%85%AE&action=edit&redlink=1" class="new" title="替前列酮（页面不存在）">替前列酮</a>（英语：<a href="https://en.wikipedia.org/wiki/Tibolone" class="extiw" title="en:Tibolone">Tibolone</a>）)</li> <li><a href="/w/index.php?title=%E6%B0%AF%E7%B1%B3%E9%85%AE&action=edit&redlink=1" class="new" title="氯米酮（页面不存在）">氯米酮</a>（英语：<a href="https://en.wikipedia.org/wiki/Clomestrone" class="extiw" title="en:Clomestrone">Clomestrone</a>）</li> <li><a href="/wiki/%E9%86%8B%E9%85%B8%E9%82%BB%E9%9B%8C%E4%BA%8C%E9%86%87" title="醋酸邻雌二醇">醋酸邻雌二醇</a></li> <li><a href="/w/index.php?title=%E5%85%B1%E8%BD%AD%E9%9B%8C%E4%B8%89%E9%86%87&action=edit&redlink=1" class="new" title="共轭雌三醇（页面不存在）">共轭雌三醇</a>（英语：<a href="https://en.wikipedia.org/wiki/Conjugated_estriol" class="extiw" title="en:Conjugated estriol">Conjugated estriol</a>）</li> <li><a href="/w/index.php?title=%E5%85%B1%E8%BD%AD%E9%9B%8C%E6%BF%80%E7%B4%A0&action=edit&redlink=1" class="new" title="共轭雌激素（页面不存在）">共轭雌激素</a>（英语：<a href="https://en.wikipedia.org/wiki/Conjugated_estrogens" class="extiw" title="en:Conjugated estrogens">Conjugated estrogens</a>）</li> <li><a href="/w/index.php?title=%E7%8E%AF%E9%9B%8C%E4%B8%89%E9%86%87&action=edit&redlink=1" class="new" title="环雌三醇（页面不存在）">环雌三醇</a>（英语：<a href="https://en.wikipedia.org/wiki/Epiestriol" class="extiw" title="en:Epiestriol">Epiestriol</a>）</li> <li><a href="/w/index.php?title=%E7%8E%AF%E9%9B%8C%E7%94%B2%E9%85%AE&action=edit&redlink=1" class="new" title="环雌甲酮（页面不存在）">环雌甲酮</a>（英语：<a href="https://en.wikipedia.org/wiki/Epimestrol" class="extiw" title="en:Epimestrol">Epimestrol</a>）</li> <li><a href="/w/index.php?title=%E9%85%AF%E5%8C%96%E9%9B%8C%E6%BF%80%E7%B4%A0&action=edit&redlink=1" class="new" title="酯化雌激素（页面不存在）">酯化雌激素</a>（英语：<a href="https://en.wikipedia.org/wiki/Esterified_estrogens" class="extiw" title="en:Esterified estrogens">Esterified estrogens</a>）</li> <li><a href="/wiki/%E9%9B%8C%E5%9B%9B%E9%86%87" title="雌四醇">雌四醇</a>†</li> <li><a href="/wiki/%E9%9B%8C%E4%BA%8C%E9%86%87" title="雌二醇">雌二醇</a></li> <li><a href="/w/index.php?title=List_of_estrogen_esters&action=edit&redlink=1" class="new" title="List of estrogen esters（页面不存在）">Estradiol esters</a> (e.g., <a href="/w/index.php?title=Estradiol_acetate&action=edit&redlink=1" class="new" title="Estradiol acetate（页面不存在）">estradiol acetate</a>, <a href="/w/index.php?title=Estradiol_benzoate&action=edit&redlink=1" class="new" title="Estradiol benzoate（页面不存在）">estradiol benzoate</a>, <a href="/w/index.php?title=Estradiol_cypionate&action=edit&redlink=1" class="new" title="Estradiol cypionate（页面不存在）">estradiol cypionate</a>, <a href="/w/index.php?title=Estradiol_enanthate&action=edit&redlink=1" class="new" title="Estradiol enanthate（页面不存在）">estradiol enanthate</a>, <a href="/w/index.php?title=Estradiol_undecylate&action=edit&redlink=1" class="new" title="Estradiol undecylate（页面不存在）">estradiol undecylate</a>, <a href="/wiki/%E6%88%8A%E9%85%B8%E9%9B%8C%E4%BA%8C%E9%86%87" title="戊酸雌二醇">estradiol valerate</a>, <a href="/wiki/Polyestradiol_phosphate" class="mw-redirect" title="Polyestradiol phosphate">polyestradiol phosphate</a>, <a href="/w/index.php?title=Estradiol_ester_mixture&action=edit&redlink=1" class="new" title="Estradiol ester mixture（页面不存在）">estradiol ester mixture</a>s (<a href="/w/index.php?title=Climacteron&action=edit&redlink=1" class="new" title="Climacteron（页面不存在）">Climacteron</a>))</li> <li><a href="/w/index.php?title=Estramustine_phosphate&action=edit&redlink=1" class="new" title="Estramustine phosphate（页面不存在）">Estramustine phosphate</a></li> <li><a href="/w/index.php?title=Estriol_(medication)&action=edit&redlink=1" class="new" title="Estriol (medication)（页面不存在）">Estriol</a></li> <li><a href="/w/index.php?title=List_of_estrogen_esters&action=edit&redlink=1" class="new" title="List of estrogen esters（页面不存在）">Estriol esters</a> (e.g., <a href="/w/index.php?title=Estriol_succinate&action=edit&redlink=1" class="new" title="Estriol succinate（页面不存在）">estriol succinate</a>, <a href="/w/index.php?title=Polyestriol_phosphate&action=edit&redlink=1" class="new" title="Polyestriol phosphate（页面不存在）">polyestriol phosphate</a>)</li> <li><a href="/w/index.php?title=Estrogenic_substances&action=edit&redlink=1" class="new" title="Estrogenic substances（页面不存在）">Estrogenic substances</a></li> <li><a href="/w/index.php?title=Estrone_(medication)&action=edit&redlink=1" class="new" title="Estrone (medication)（页面不存在）">Estrone</a></li> <li><a href="/w/index.php?title=List_of_estrogen_esters&action=edit&redlink=1" class="new" title="List of estrogen esters（页面不存在）">Estrone esters</a></li> <li>* <a href="/w/index.php?title=Estrone_sulfate_(medication)&action=edit&redlink=1" class="new" title="Estrone sulfate (medication)（页面不存在）">Estrone sulfate</a></li> <li>* <a href="/w/index.php?title=Estropipate&action=edit&redlink=1" class="new" title="Estropipate（页面不存在）">Estropipate (piperazine estrone sulfate)</a></li> <li><a href="/w/index.php?title=Ethinylestradiol&action=edit&redlink=1" class="new" title="Ethinylestradiol（页面不存在）">Ethinylestradiol</a>#</li> <li>* <a href="/w/index.php?title=Ethinylestradiol_sulfonate&action=edit&redlink=1" class="new" title="Ethinylestradiol sulfonate（页面不存在）">Ethinylestradiol sulfonate</a></li> <li><a href="/w/index.php?title=Hydroxyestrone_diacetate&action=edit&redlink=1" class="new" title="Hydroxyestrone diacetate（页面不存在）">Hydroxyestrone diacetate</a></li> <li><a href="/w/index.php?title=Mestranol&action=edit&redlink=1" class="new" title="Mestranol（页面不存在）">Mestranol</a></li> <li><a href="/w/index.php?title=Methylestradiol&action=edit&redlink=1" class="new" title="Methylestradiol（页面不存在）">Methylestradiol</a></li> <li><a href="/w/index.php?title=Moxestrol&action=edit&redlink=1" class="new" title="Moxestrol（页面不存在）">Moxestrol</a></li> <li><a href="/w/index.php?title=Nilestriol&action=edit&redlink=1" class="new" title="Nilestriol（页面不存在）">Nilestriol</a></li> <li><a href="/w/index.php?title=Prasterone&action=edit&redlink=1" class="new" title="Prasterone（页面不存在）">Prasterone (dehydroepiandrosterone; DHEA)</a></li> <li><a href="/w/index.php?title=Prasterone_enanthate&action=edit&redlink=1" class="new" title="Prasterone enanthate（页面不存在）">Prasterone enanthate</a></li> <li><a href="/w/index.php?title=Prasterone_sulfate&action=edit&redlink=1" class="new" title="Prasterone sulfate（页面不存在）">Prasterone sulfate</a></li> <li><a href="/w/index.php?title=Promestriene&action=edit&redlink=1" class="new" title="Promestriene（页面不存在）">Promestriene</a></li> <li><a href="/w/index.php?title=Quinestradol&action=edit&redlink=1" class="new" title="Quinestradol（页面不存在）">Quinestradol</a></li> <li><a href="/w/index.php?title=Quinestrol&action=edit&redlink=1" class="new" title="Quinestrol（页面不存在）">Quinestrol</a></li></ol> <ol><li>（<a href="/w/index.php?title=%E9%9D%9E%E7%94%BE%E9%AB%94&action=edit&redlink=1" class="new" title="非甾體（页面不存在）">非甾體類</a>（英语：<a href="https://en.wikipedia.org/wiki/Nonsteroidal" class="extiw" title="en:Nonsteroidal">Nonsteroidal</a>）） <a href="/w/index.php?title=Benzestrol&action=edit&redlink=1" class="new" title="Benzestrol（页面不存在）">Benzestrol</a></li> <li><a href="/w/index.php?title=Bifluranol&action=edit&redlink=1" class="new" title="Bifluranol（页面不存在）">Bifluranol</a></li> <li><a href="/w/index.php?title=Chlorotrianisene&action=edit&redlink=1" class="new" title="Chlorotrianisene（页面不存在）">Chlorotrianisene</a></li> <li><a href="/w/index.php?title=Dienestrol&action=edit&redlink=1" class="new" title="Dienestrol（页面不存在）">Dienestrol</a></li> <li><a href="/w/index.php?title=%E5%8F%8C%E4%B9%99%E9%85%B8%E5%8F%8C%E7%83%AF%E9%9B%8C%E9%85%9A&action=edit&redlink=1" class="new" title="双乙酸双烯雌酚（页面不存在）">双乙酸双烯雌酚</a>（英语：<a href="https://en.wikipedia.org/wiki/Dienestrol_diacetate" class="extiw" title="en:Dienestrol diacetate">Dienestrol diacetate</a>）</li> <li><a href="/wiki/%E4%B9%99%E7%83%AF%E9%9B%8C%E9%85%9A" title="乙烯雌酚">乙烯雌酚</a>（<a href="/wiki/%E5%B7%B1%E7%83%AF%E9%9B%8C%E9%85%9A" title="己烯雌酚">己烯雌酚</a>(stilbestrol)）</li> <li><a href="/w/index.php?title=List_of_estrogen_esters&action=edit&redlink=1" class="new" title="List of estrogen esters（页面不存在）">Diethylstilbestrol esters/ethers</a></li> <li><a href="/w/index.php?title=Dimestrol&action=edit&redlink=1" class="new" title="Dimestrol（页面不存在）">Dimestrol (diethylstilbestrol dimethyl ether)</a></li> <li><a href="/w/index.php?title=Fosfestrol&action=edit&redlink=1" class="new" title="Fosfestrol（页面不存在）">Fosfestrol (diethylstilbestrol diphosphate)</a></li> <li><a href="/w/index.php?title=Mestilbol&action=edit&redlink=1" class="new" title="Mestilbol（页面不存在）">Mestilbol (diethylstilbestrol monomethyl ether)</a></li> <li><a href="/w/index.php?title=Doisynoestrol&action=edit&redlink=1" class="new" title="Doisynoestrol（页面不存在）">Doisynoestrol (fenocycline)</a></li> <li><a href="/w/index.php?title=Hexestrol&action=edit&redlink=1" class="new" title="Hexestrol（页面不存在）">Hexestrol</a></li> <li><a href="/w/index.php?title=List_of_estrogen_esters&action=edit&redlink=1" class="new" title="List of estrogen esters（页面不存在）">Hexestrol esters</a></li> <li><a href="/w/index.php?title=Methallenestril&action=edit&redlink=1" class="new" title="Methallenestril（页面不存在）">Methallenestril</a></li> <li><a href="/w/index.php?title=Methestrol&action=edit&redlink=1" class="new" title="Methestrol（页面不存在）">Methestrol (promethestrol)</a></li> <li><a href="/w/index.php?title=Methestrol_dipropionate&action=edit&redlink=1" class="new" title="Methestrol dipropionate（页面不存在）">Methestrol dipropionate (promethestrol dipropionate)</a></li> <li><a href="/w/index.php?title=Paroxypropione&action=edit&redlink=1" class="new" title="Paroxypropione（页面不存在）">Paroxypropione</a></li> <li><a href="/w/index.php?title=Quadrosilan&action=edit&redlink=1" class="new" title="Quadrosilan（页面不存在）">Quadrosilan</a></li> <li><a href="/w/index.php?title=Triphenylbromoethylene&action=edit&redlink=1" class="new" title="Triphenylbromoethylene（页面不存在）">Triphenylbromoethylene</a></li> <li><a href="/w/index.php?title=Triphenylchloroethylene&action=edit&redlink=1" class="new" title="Triphenylchloroethylene（页面不存在）">Triphenylchloroethylene</a></li> <li><a href="/w/index.php?title=Zeranol&action=edit&redlink=1" class="new" title="Zeranol（页面不存在）">Zeranol</a></li></ol> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:10em;;text-align:center;"><a href="/wiki/%E4%BF%83%E6%80%A7%E8%85%BA%E6%BF%80%E7%B4%A0" title="促性腺激素">促性腺激素</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E6%8A%97%E9%9B%84%E6%BF%80%E7%B4%A0" title="抗雄激素">抗雄激素</a> (例如<a href="/wiki/%E6%AF%94%E5%8D%A1%E9%AD%AF%E8%83%BA" title="比卡魯胺">比卡鲁胺</a>（英语：<a href="https://en.wikipedia.org/wiki/bicalutamide" class="extiw" title="en:bicalutamide">bicalutamide</a>）)</li> <li><a href="/w/index.php?title=%E4%BF%83%E6%80%A7%E8%85%BA%E6%BF%80%E7%B4%A0%E9%87%8A%E6%94%BE%E6%BF%80%E7%B4%A0%E6%BF%80%E5%8A%A8%E5%89%82&action=edit&redlink=1" class="new" title="促性腺激素释放激素激动剂（页面不存在）"><abbr title="促性腺激素释放激素">GnRH</abbr>拮抗剂</a>（英语：<a href="https://en.wikipedia.org/wiki/GnRH_agonist" class="extiw" title="en:GnRH agonist">GnRH agonist</a>） (例如<a href="/wiki/%E4%BF%83%E6%80%A7%E8%85%BA%E6%BF%80%E7%B4%A0%E9%87%8A%E6%94%BE%E6%BF%80%E7%B4%A0" title="促性腺激素释放激素"><abbr title="促性腺激素释放激素">GnRH</abbr> (促性腺激素)</a>, <a href="/wiki/%E4%BA%AE%E4%B8%99%E7%91%9E%E6%9E%97" title="亮丙瑞林">亮丙瑞林</a>)</li> <li><a href="/wiki/%E4%BF%83%E6%80%A7%E8%85%BA%E6%BF%80%E7%B4%A0" title="促性腺激素">促性腺激素</a>(例如<a href="/wiki/%E4%BF%83%E5%8D%B5%E6%B3%A1%E6%BF%80%E7%B4%A0" title="促卵泡激素"><abbr title="促卵泡激素">FSH</abbr></a>, <a href="/wiki/%E9%BB%84%E4%BD%93%E7%94%9F%E6%88%90%E7%B4%A0" title="黄体生成素"><abbr title="黄体生成素">LH</abbr></a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center;"><a href="/w/index.php?title=%E6%8A%97%E9%9B%8C%E6%BF%80%E7%B4%A0&action=edit&redlink=1" class="new" title="抗雌激素（页面不存在）">抗雌激素</a>（英语：<a href="https://en.wikipedia.org/wiki/Antiestrogen" class="extiw" title="en:Antiestrogen">Antiestrogen</a>）</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px;background:#DDDDFF;"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:10em;;text-align:center;"><a href="/w/index.php?title=%E9%9B%8C%E6%BF%80%E7%B4%A0%E5%8F%97%E4%BD%93&action=edit&redlink=1" class="new" title="雌激素受体（页面不存在）"><abbr title="雌激素受体">ER</abbr></a>拮抗剂 (包含<a href="/wiki/%E9%80%89%E6%8B%A9%E6%80%A7%E9%9B%8C%E6%BF%80%E7%B4%A0%E5%8F%97%E4%BD%93%E8%B0%83%E8%8A%82%E5%89%82" class="mw-redirect" title="选择性雌激素受体调节剂"><abbr title="选择性雌激素受体调节剂">SERMs</abbr></a>/<a href="/w/index.php?title=%E9%80%89%E6%8B%A9%E6%80%A7%E9%9B%8C%E6%BF%80%E7%B4%A0%E5%8F%97%E4%BD%93%E4%B8%8B%E8%B0%83%E5%9B%A0%E5%AD%90&action=edit&redlink=1" class="new" title="选择性雌激素受体下调因子（页面不存在）"><abbr title="选择性雌激素受体下调因子">SERDs</abbr></a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0px"><div style="padding:0em 0.25em"> <ol><li><a href="/wiki/%E5%BC%82%E7%82%94%E8%AF%BA%E9%85%AE" title="异炔诺酮">异炔诺酮</a>†</li> <li><a href="/w/index.php?title=%E9%98%BF%E8%AF%BA%E5%B0%94%E5%AE%9A&action=edit&redlink=1" class="new" title="阿诺尔定（页面不存在）">阿诺尔定</a>（英语：<a href="https://en.wikipedia.org/wiki/Anordrin" class="extiw" title="en:Anordrin">Anordrin</a>）</li> <li><a href="/w/index.php?title=%E8%B4%9D%E9%82%A3%E6%99%AE%E5%88%A9&action=edit&redlink=1" class="new" title="贝那普利（页面不存在）">贝那普利</a>（英语：<a href="https://en.wikipedia.org/wiki/Bazedoxifene" class="extiw" title="en:Bazedoxifene">Bazedoxifene</a>）</li> <li><a href="/w/index.php?title=%E6%BA%B4%E4%B8%99%E9%9B%8C%E9%85%9A&action=edit&redlink=1" class="new" title="溴丙雌酚（页面不存在）">溴丙雌酚</a>（英语：<a href="https://en.wikipedia.org/wiki/Broparestrol" class="extiw" title="en:Broparestrol">Broparestrol</a>）</li> <li><a href="/w/index.php?title=%E5%8F%AF%E6%B4%9B%E7%B1%B3%E8%8A%AC&action=edit&redlink=1" class="new" title="可洛米芬（页面不存在）">可洛米芬</a>#</li> <li><a href="/w/index.php?title=%E7%8E%AF%E8%8B%AF%E5%9F%BA%E9%85%9A&action=edit&redlink=1" class="new" title="环苯基酚（页面不存在）">环苯基酚</a>（英语：<a href="https://en.wikipedia.org/wiki/Cyclofenil" class="extiw" title="en:Cyclofenil">Cyclofenil</a>）</li> <li><a href="/w/index.php?title=%E5%B7%A6%E6%97%8B%E6%B0%AF%E7%B1%B3%E8%8A%AC&action=edit&redlink=1" class="new" title="左旋氯米芬（页面不存在）">左旋氯米芬</a>（英语：<a href="https://en.wikipedia.org/wiki/Enclomifene" class="extiw" title="en:Enclomifene">Enclomifene</a>）†</li> <li><a href="/w/index.php?title=%E4%BE%9D%E5%8C%B9%E6%9B%BF%E5%8F%B8%E9%86%87&action=edit&redlink=1" class="new" title="依匹替司醇（页面不存在）">依匹替司醇</a>（英语：<a href="https://en.wikipedia.org/wiki/Epitiostanol" class="extiw" title="en:Epitiostanol">Epitiostanol</a>）</li> <li><a href="/w/index.php?title=%E6%8B%89%E7%B4%A2%E7%91%9E%E7%83%AF&action=edit&redlink=1" class="new" title="拉索瑞烯（页面不存在）">拉索瑞烯</a>（英语：<a href="https://en.wikipedia.org/wiki/Lasofoxifene" class="extiw" title="en:Lasofoxifene">Lasofoxifene</a>）</li> <li><a href="/w/index.php?title=%E7%BE%8E%E5%8C%B9%E6%9B%BF%E5%9D%A6&action=edit&redlink=1" class="new" title="美匹替坦（页面不存在）">美匹替坦</a>（英语：<a href="https://en.wikipedia.org/wiki/Mepitiostane" class="extiw" title="en:Mepitiostane">Mepitiostane</a>）</li> <li><a href="/w/index.php?title=%E5%A5%A5%E7%BE%8E%E6%B4%9B%E6%98%94%E8%8A%AC&action=edit&redlink=1" class="new" title="奥美洛昔芬（页面不存在）">奥美洛昔芬</a>（英语：<a href="https://en.wikipedia.org/wiki/Ormeloxifene" class="extiw" title="en:Ormeloxifene">Ormeloxifene</a>）</li> <li><a href="/w/index.php?title=%E5%A5%A5%E5%8F%B8%E8%B4%9D%E9%BA%A6%E8%8A%AC&action=edit&redlink=1" class="new" title="奥司贝麦芬（页面不存在）">奥司贝麦芬</a>（英语：<a href="https://en.wikipedia.org/wiki/Ospemifene" class="extiw" title="en:Ospemifene">Ospemifene</a>）</li> <li><a href="/wiki/%E9%9B%B7%E6%B4%9B%E6%98%94%E8%8A%AC" title="雷洛昔芬">雷洛昔芬</a></li> <li><a href="/wiki/%E4%BB%96%E8%8E%AB%E6%98%94%E8%8A%AC" title="他莫昔芬">他莫昔芬</a>#</li> <li><a href="/w/index.php?title=%E6%89%98%E7%91%9E%E7%B1%B3%E8%8A%AC&action=edit&redlink=1" class="new" title="托瑞米芬（页面不存在）">托瑞米芬</a>（英语：<a href="https://en.wikipedia.org/wiki/Toremifene" class="extiw" title="en:Toremifene">Toremifene</a>）</li> <li>（完全抗性的） <a href="/w/index.php?title=%E4%BE%9D%E7%91%9E%E9%9B%8C%E8%8B%B7&action=edit&redlink=1" class="new" title="依瑞雌苷（页面不存在）">依瑞雌苷</a>（英语：<a href="https://en.wikipedia.org/wiki/Elacestrant" class="extiw" title="en:Elacestrant">Elacestrant</a>）</li> <li><a href="/w/index.php?title=%E6%B0%9F%E7%B6%AD%E5%8F%B8%E7%BE%A4&action=edit&redlink=1" class="new" title="氟維司群（页面不存在）">氟維司群</a>（英语：<a href="https://en.wikipedia.org/wiki/Fulvestrant" class="extiw" title="en:Fulvestrant">Fulvestrant</a>）</li> <li>（不完全抗性的） <a href="/w/index.php?title=%E6%9B%B2%E6%B4%9B%E5%8F%B8%E5%9D%A6&action=edit&redlink=1" class="new" title="曲洛司坦（页面不存在）">曲洛司坦</a>（英语：<a href="https://en.wikipedia.org/wiki/Trilostane" class="extiw" title="en:Trilostane">Trilostane</a>）</li></ol> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:10em;;text-align:center;"><a href="/w/index.php?title=%E8%8A%B3%E9%A6%99%E9%85%B6%E6%8A%91%E5%88%B6%E5%89%82&action=edit&redlink=1" class="new" title="芳香酶抑制剂（页面不存在）">芳香酶抑制剂</a>（英语：<a href="https://en.wikipedia.org/wiki/Aromatase_inhibitor" class="extiw" title="en:Aromatase inhibitor">Aromatase inhibitor</a>）</th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0px"><div style="padding:0em 0.25em"> <ul><li>（第一代） <a href="/w/index.php?title=%E6%B0%A8%E9%AD%AF%E7%B1%B3%E7%89%B9&action=edit&redlink=1" class="new" title="氨魯米特（页面不存在）">氨魯米特</a>（英语：<a href="https://en.wikipedia.org/wiki/Aminoglutethimide" class="extiw" title="en:Aminoglutethimide">Aminoglutethimide</a>）</li> <li><a href="/w/index.php?title=%E6%B3%B0%E5%8F%B8%E6%89%98%E9%BE%99&action=edit&redlink=1" class="new" title="泰司托龙（页面不存在）">泰司托龙</a>（英语：<a href="https://en.wikipedia.org/wiki/Testolactone" class="extiw" title="en:Testolactone">Testolactone</a>）</li></ul> <ul><li>（第二代） <a href="/w/index.php?title=%E6%B3%95%E5%A4%9A%E8%90%A8%E5%B0%94&action=edit&redlink=1" class="new" title="法多萨尔（页面不存在）">法多萨尔</a>（英语：<a href="https://en.wikipedia.org/wiki/Fadrozole" class="extiw" title="en:Fadrozole">Fadrozole</a>）</li> <li><a href="/w/index.php?title=%E7%94%B2%E7%83%AF%E6%9B%B2%E9%85%AE&action=edit&redlink=1" class="new" title="甲烯曲酮（页面不存在）">甲烯曲酮</a>（英语：<a href="https://en.wikipedia.org/wiki/Formestane" class="extiw" title="en:Formestane">Formestane</a>）</li></ul> <ul><li>（第三代） <a class="mw-selflink selflink">阿那曲唑</a></li> <li><a href="/wiki/%E4%BE%9D%E8%A5%BF%E7%BE%8E%E5%9D%A6" title="依西美坦">依西美坦</a></li> <li><a href="/w/index.php?title=%E5%88%A9%E5%A6%A5%E6%98%94%E5%8D%95&action=edit&redlink=1" class="new" title="利妥昔单（页面不存在）">利妥昔单</a>（英语：<a href="https://en.wikipedia.org/wiki/Letrozole" class="extiw" title="en:Letrozole">Letrozole</a>）</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:10em;;text-align:center;"><a href="/w/index.php?title=%E6%8A%97%E6%80%A7%E8%85%BA%E6%BF%80%E7%B4%A0&action=edit&redlink=1" class="new" title="抗性腺激素（页面不存在）">抗性腺激素</a>（英语：<a href="https://en.wikipedia.org/wiki/Antigonadal_hormone" class="extiw" title="en:Antigonadal hormone">Antigonadal hormone</a>）</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E9%9B%84%E6%BF%80%E7%B4%A0" title="雄激素">雄激素</a>/<a href="/w/index.php?title=%E5%90%88%E6%88%90%E9%A1%9E%E5%9B%BA%E9%85%AE&action=edit&redlink=1" class="new" title="合成類固酮（页面不存在）">合成類固酮</a>（英语：<a href="https://en.wikipedia.org/wiki/anabolic_steroid" class="extiw" title="en:anabolic steroid">anabolic steroid</a>） (例如 <a href="/wiki/%E7%9D%AA%E9%85%AE" class="mw-redirect" title="睪酮">睪酮</a>, <a href="/w/index.php?title=%E9%9B%84%E6%BF%80%E7%B4%A0%E9%85%AF%E5%88%97%E8%A1%A8&action=edit&redlink=1" class="new" title="雄激素酯列表（页面不存在）">睪酮酯</a>（英语：<a href="https://en.wikipedia.org/wiki/List_of_androgen_esters#Testosterone_esters" class="extiw" title="en:List of androgen esters">List of androgen esters#Testosterone esters</a>）, <a href="/w/index.php?title=List_of_androgen_esters&action=edit&redlink=1" class="new" title="List of androgen esters（页面不存在）">nandrolone esters</a>, <a href="/w/index.php?title=Oxandrolone&action=edit&redlink=1" class="new" title="Oxandrolone（页面不存在）">oxandrolone</a>, <a href="/w/index.php?title=%E6%B0%9F%E6%B0%A7%E5%AD%95%E9%85%AE&action=edit&redlink=1" class="new" title="氟氧孕酮（页面不存在）">氟氧孕酮</a>（英语：<a href="https://en.wikipedia.org/wiki/fluoxymesterone" class="extiw" title="en:fluoxymesterone">fluoxymesterone</a>）)</li> <li><a href="/wiki/D2_receptor" class="mw-redirect" title="D2 receptor">D2 receptor</a> <a href="/w/index.php?title=Dopamine_antagonist&action=edit&redlink=1" class="new" title="Dopamine antagonist（页面不存在）">antagonist</a>s (<a href="/wiki/Prolactin" class="mw-redirect" title="Prolactin">prolactin</a> releasers) (e.g., <a href="/w/index.php?title=Domperidone&action=edit&redlink=1" class="new" title="Domperidone（页面不存在）">domperidone</a>, <a href="/wiki/Metoclopramide" class="mw-redirect" title="Metoclopramide">metoclopramide</a>, <a href="/w/index.php?title=Risperidone&action=edit&redlink=1" class="new" title="Risperidone（页面不存在）">risperidone</a>, <a href="/w/index.php?title=Haloperidol&action=edit&redlink=1" class="new" title="Haloperidol（页面不存在）">haloperidol</a>, <a href="/wiki/Chlorpromazine" class="mw-redirect" title="Chlorpromazine">chlorpromazine</a>, <a href="/w/index.php?title=Sulpiride&action=edit&redlink=1" class="new" title="Sulpiride（页面不存在）">sulpiride</a>)</li> <li><a href="/w/index.php?title=GnRH_agonist&action=edit&redlink=1" class="new" title="GnRH agonist（页面不存在）"><abbr title="gonadotropin-releasing hormone">GnRH</abbr> agonist</a>s (e.g., <a href="/w/index.php?title=Leuprorelin&action=edit&redlink=1" class="new" title="Leuprorelin（页面不存在）">leuprorelin</a>, <a href="/w/index.php?title=Goserelin&action=edit&redlink=1" class="new" title="Goserelin（页面不存在）">goserelin</a>)</li> <li><a href="/w/index.php?title=GnRH_antagonist&action=edit&redlink=1" class="new" title="GnRH antagonist（页面不存在）"><abbr title="gonadotropin-releasing hormone">GnRH</abbr> antagonist</a>s (e.g., <a href="/w/index.php?title=Cetrorelix&action=edit&redlink=1" class="new" title="Cetrorelix（页面不存在）">cetrorelix</a>, <a href="/w/index.php?title=Elagolix&action=edit&redlink=1" class="new" title="Elagolix（页面不存在）">elagolix</a>)</li> <li><a href="/w/index.php?title=Progestogen&action=edit&redlink=1" class="new" title="Progestogen（页面不存在）">Progestogen</a>s (e.g., <a href="/w/index.php?title=Chlormadinone_acetate&action=edit&redlink=1" class="new" title="Chlormadinone acetate（页面不存在）">chlormadinone acetate</a>, <a href="/wiki/Cyproterone_acetate" class="mw-redirect" title="Cyproterone acetate">cyproterone acetate</a>, <a href="/w/index.php?title=Gestonorone_caproate&action=edit&redlink=1" class="new" title="Gestonorone caproate（页面不存在）">gestonorone caproate</a>, <a href="/w/index.php?title=Hydroxyprogesterone_caproate&action=edit&redlink=1" class="new" title="Hydroxyprogesterone caproate（页面不存在）">hydroxyprogesterone caproate</a>, <a href="/w/index.php?title=Medroxyprogesterone_acetate&action=edit&redlink=1" class="new" title="Medroxyprogesterone acetate（页面不存在）">medroxyprogesterone acetate</a>, <a href="/w/index.php?title=Megestrol_acetate&action=edit&redlink=1" class="new" title="Megestrol acetate（页面不存在）">megestrol acetate</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:10em;;text-align:center;">其他</th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0px"><div style="padding:0em 0.25em"> <ul><li>混合作用机制:<a href="/w/index.php?title=Danazol&action=edit&redlink=1" class="new" title="Danazol（页面不存在）">Danazol</a></li> <li><a href="/w/index.php?title=Gestrinone&action=edit&redlink=1" class="new" title="Gestrinone（页面不存在）">Gestrinone</a></li></ul> <ul><li><a href="/wiki/%E9%9B%84%E7%83%AF%E4%BA%8C%E9%85%AE" title="雄烯二酮">雄烯二酮</a><a href="/wiki/%E6%8A%97%E5%8E%9F" title="抗原">抗原</a>: <a href="/w/index.php?title=Androvax(%E9%9B%84%E7%83%AF%E4%BA%8C%E9%85%AE%E7%99%BD%E8%9B%8B%E7%99%BD)&action=edit&redlink=1" class="new" title="Androvax(雄烯二酮白蛋白)（页面不存在）">Androvax(雄烯二酮白蛋白)</a>（英语：<a href="https://en.wikipedia.org/wiki/Androvax" class="extiw" title="en:Androvax">Androvax</a>）</li> <li><a href="/w/index.php?title=Ovandrotone_albumin_(Fecundin)&action=edit&redlink=1" class="new" title="Ovandrotone albumin (Fecundin)（页面不存在）">Ovandrotone albumin (Fecundin)</a>（英语：<a href="https://en.wikipedia.org/wiki/Ovandrotone_albumin" class="extiw" title="en:Ovandrotone albumin">Ovandrotone albumin</a>）</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0px;background:#DDDDFF;"><div style="padding:0em 0.25em"><div class="hlist"> <ul><li>#<a href="/wiki/%E4%B8%96%E7%95%8C%E5%8D%AB%E7%94%9F%E7%BB%84%E7%BB%87%E5%9F%BA%E6%9C%AC%E8%8D%AF%E7%89%A9%E6%A0%87%E5%87%86%E6%B8%85%E5%8D%95" title="世界卫生组织基本药物标准清单">世卫基本药物（WHO-EM）</a></li> <li>‡从市场<a href="/wiki/%E6%92%A4%E5%9B%9E%E8%8D%AF%E5%93%81%E5%88%97%E8%A1%A8" title="撤回药品列表">撤回</a></li> <li>†<a href="/wiki/%E8%87%A8%E5%BA%8A%E8%A9%A6%E9%A9%97" title="臨床試驗">臨床試驗</a><a href="/wiki/%E8%87%A8%E5%BA%8A%E8%A9%A6%E9%A9%97#Ⅲ期临床试验" title="臨床試驗">第三階段</a></li> <li>§臨床試驗<a href="/wiki/%E8%87%A8%E5%BA%8A%E8%A9%A6%E9%A9%97#Ⅱ期临床试验" title="臨床試驗">未到第三階段</a></li></ul> </div> <dl><dt>參見</dt> <dd><a href="/w/index.php?title=%E9%9B%8C%E6%BF%80%E7%B4%A0%E5%8F%97%E4%BD%93%E8%B0%83%E8%8A%82%E5%89%82%EF%BC%88%E6%A8%A1%E6%9D%BF%EF%BC%89&action=edit&redlink=1" class="new" title="雌激素受体调节剂（模板）（页面不存在）">雌激素受体调节剂（模板）</a>（：<a href="/w/index.php?title=EnTemplate:Estrogen_receptor_modulators:%E9%9B%8C%E6%BF%80%E7%B4%A0%E5%8F%97%E4%BD%93%E8%B0%83%E8%8A%82%E5%89%82%EF%BC%88%E6%A8%A1%E6%9D%BF%EF%BC%89&action=edit&redlink=1" class="new" title="EnTemplate:Estrogen receptor modulators:雌激素受体调节剂（模板）（页面不存在）">雌激素受体调节剂（模板）</a>）</dd> <dd><a href="/w/index.php?title=%E9%9B%84%E6%BF%80%E7%B4%A0%E5%92%8C%E6%8A%97%E9%9B%84%E6%BF%80%E7%B4%A0%EF%BC%88%E6%A8%A1%E6%9D%BF%EF%BC%89&action=edit&redlink=1" class="new" title="雄激素和抗雄激素（模板）（页面不存在）">雄激素和抗雄激素（模板）</a>（英语：<a href="https://en.wikipedia.org/wiki/Template:Androgens_and_antiandrogens" class="extiw" title="en:Template:Androgens and antiandrogens">Template:Androgens and antiandrogens</a>）</dd> <dd><a href="/w/index.php?title=%E5%AD%95%E6%BF%80%E7%B4%A0%E5%92%8C%E6%8A%97%E5%AD%95%E6%BF%80%E7%B4%A0%EF%BC%88%E6%A8%A1%E6%9D%BF%EF%BC%89&action=edit&redlink=1" class="new" title="孕激素和抗孕激素（模板）（页面不存在）">孕激素和抗孕激素（模板）</a>（英语：<a href="https://en.wikipedia.org/wiki/Template:Progestogens_and_antiprogestogens" class="extiw" title="en:Template:Progestogens and antiprogestogens">Template:Progestogens and antiprogestogens</a>）</dd> <dd><a href="/w/index.php?title=%E9%9B%8C%E6%BF%80%E7%B4%A0%E5%88%97%E8%A1%A8&action=edit&redlink=1" class="new" title="雌激素列表（页面不存在）">雌激素列表</a>（英语：<a href="https://en.wikipedia.org/wiki/List_of_steroidal_estrogens" class="extiw" title="en:List of steroidal estrogens">List of steroidal estrogens</a>）</dd></dl></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84265675"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84261037"></div><div role="navigation" class="navbox" aria-labelledby="阿斯利康制药" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="collapsible-title navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84265675"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r84244141"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:%E9%98%BF%E6%96%AF%E5%88%A9%E5%BA%B7%E5%88%B6%E8%8D%AF" title="Template:阿斯利康制药"><abbr title="查看该模板">查</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:%E9%98%BF%E6%96%AF%E5%88%A9%E5%BA%B7%E5%88%B6%E8%8D%AF" title="Template talk:阿斯利康制药"><abbr title="讨论该模板">论</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:%E7%BC%96%E8%BE%91%E9%A1%B5%E9%9D%A2/Template:%E9%98%BF%E6%96%AF%E5%88%A9%E5%BA%B7%E5%88%B6%E8%8D%AF" title="Special:编辑页面/Template:阿斯利康制药"><abbr title="编辑该模板">编</abbr></a></li></ul></div><div id="阿斯利康制药" style="font-size:110%;margin:0 5em"><a href="/wiki/%E9%98%BF%E6%96%AF%E5%88%A9%E5%BA%B7" title="阿斯利康">阿斯利康制药</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">产品</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a class="mw-selflink selflink">阿那曲唑</a></li> <li><a href="/wiki/%E9%98%BF%E6%9B%BF%E6%B4%9B%E5%B0%94" title="阿替洛尔">阿替洛尔</a></li> <li><a href="/wiki/%E6%BA%B4%E8%8B%AF%E9%82%A3%E6%95%8F" title="溴苯那敏">溴苯那敏</a></li> <li><a href="/wiki/%E5%B8%83%E5%9C%B0%E5%A5%88%E5%BE%B7" title="布地奈德">布地奈德</a></li> <li><a href="/wiki/%E5%BA%A6%E4%BC%90%E5%88%A9%E5%B0%A4%E5%8D%95%E6%8A%97" title="度伐利尤单抗">度伐利尤单抗</a></li> <li><a href="/w/index.php?title=Disufenton_sodium&action=edit&redlink=1" class="new" title="Disufenton sodium（页面不存在）">Disufenton sodium</a></li> <li><a href="/wiki/%E5%9F%83%E7%B4%A2%E7%BE%8E%E6%8B%89%E5%94%91" title="埃索美拉唑">埃索美拉唑</a></li> <li><a href="/w/index.php?title=Live_attenuated_influenza_vaccine&action=edit&redlink=1" class="new" title="Live attenuated influenza vaccine（页面不存在）">FluMist</a></li> <li><a href="/wiki/%E5%90%89%E9%9D%9E%E6%9B%BF%E5%B0%BC" title="吉非替尼">吉非替尼</a></li> <li><a href="/wiki/%E6%88%88%E8%88%8D%E7%91%9E%E6%9E%97" title="戈舍瑞林">戈舍瑞林</a></li> <li><a href="/wiki/%E5%8D%95%E7%A1%9D%E9%85%B8%E5%BC%82%E5%B1%B1%E6%A2%A8%E9%85%AF" title="单硝酸异山梨酯">‎单硝酸异山梨酯</a></li> <li><a href="/wiki/%E8%8E%AB%E7%BB%B4%E7%8F%A0%E5%8D%95%E6%8A%97" title="莫维珠单抗">莫维珠单抗</a></li> <li><a href="/wiki/%E5%A5%A5%E7%BE%8E%E6%8B%89%E5%94%91" title="奥美拉唑">奥美拉唑</a></li> <li><a href="/wiki/%E5%B8%95%E5%88%A9%E7%8F%A0%E5%8D%95%E6%8A%97" title="帕利珠单抗">帕利珠单抗</a></li> <li><a href="/wiki/%E4%B8%99%E6%B3%8A%E9%85%9A" title="丙泊酚">丙泊酚</a></li> <li><a href="/wiki/%E7%91%9E%E8%88%92%E4%BC%90%E4%BB%96%E6%B1%80" title="瑞舒伐他汀">瑞舒伐他汀</a></li> <li><a href="/wiki/%E7%BD%97%E6%B2%99%E5%8F%B8%E4%BB%96" title="罗沙司他">罗沙司他</a></li> <li><a href="/wiki/%E4%BB%96%E8%8E%AB%E6%98%94%E8%8A%AC" title="他莫昔芬">他莫昔芬</a></li> <li><a href="/wiki/%E6%9B%BF%E6%A0%BC%E7%91%9E%E6%B4%9B" title="替格瑞洛">替格瑞洛</a></li> <li><a href="/w/index.php?title=%E5%87%A1%E5%BE%B7%E4%BB%96%E5%B0%BC&action=edit&redlink=1" class="new" title="凡德他尼（页面不存在）">凡德他尼</a>（英语：<a href="https://en.wikipedia.org/wiki/Vandetanib" class="extiw" title="en:Vandetanib">Vandetanib</a>）</li> <li><a href="/wiki/%E7%89%9B%E6%B4%A5-%E9%98%BF%E6%96%AF%E5%88%A9%E5%BA%B72019%E5%86%A0%E7%8A%B6%E7%97%85%E6%AF%92%E7%97%85%E7%96%AB%E8%8B%97" title="牛津-阿斯利康2019冠状病毒病疫苗">Vaxzevria</a></li> <li><a href="/w/index.php?title=Ximelagatran&action=edit&redlink=1" class="new" title="Ximelagatran（页面不存在）">Ximelagatran</a></li> <li><a href="/wiki/%E4%BD%90%E7%B1%B3%E6%9B%B2%E6%99%AE%E5%9D%A6" title="佐米曲普坦">佐米曲普坦</a></li> <li><a href="/wiki/%E7%8E%AF%E7%A1%85%E9%85%B8%E9%94%86%E9%92%A0" title="环硅酸锆钠">利倍卓</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">前身和收购</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=%E9%98%BF%E6%96%AF%E7%89%B9%E6%8B%89%E5%85%AC%E5%8F%B8&action=edit&redlink=1" class="new" title="阿斯特拉公司（页面不存在）">阿斯特拉公司</a>（英语：<a href="https://en.wikipedia.org/wiki/Astra_AB" class="extiw" title="en:Astra AB">Astra AB</a>）</li> <li><a href="/w/index.php?title=%E5%89%91%E6%A1%A5%E6%8A%97%E4%BD%93%E7%A7%91%E6%8A%80&action=edit&redlink=1" class="new" title="剑桥抗体科技（页面不存在）">剑桥抗体科技</a></li> <li><a href="/w/index.php?title=MedImmune&action=edit&redlink=1" class="new" title="MedImmune（页面不存在）">MedImmune</a></li> <li><a href="/wiki/%E6%8D%B7%E5%88%A9%E5%BA%B7" title="捷利康">捷利康公司</a></li> <li><a href="/wiki/%E7%91%9E%E9%A2%82%E5%88%B6%E8%8D%AF" title="瑞颂制药">瑞颂制药</a></li> <li><a href="/wiki/%E4%BA%98%E5%96%9C%E7%94%9F%E7%89%A9" title="亘喜生物">亘喜生物</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">人物</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Tom_McKillop&action=edit&redlink=1" class="new" title="Tom McKillop（页面不存在）">Tom McKillop</a></li> <li><a href="/w/index.php?title=Louis_Schweitzer_(CEO)&action=edit&redlink=1" class="new" title="Louis Schweitzer (CEO)（页面不存在）">Louis Schweitzer</a></li> <li><a href="/wiki/%E8%8B%8F%E5%8D%9A%E7%A7%91" title="苏博科">苏博科</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div><img alt="分类" src="//upload.wikimedia.org/wikipedia/commons/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /> <a href="/wiki/Category:%E9%98%BF%E6%96%AF%E5%88%A9%E5%BA%B7%E5%88%B6%E8%8D%AF" title="Category:阿斯利康制药">Category:阿斯利康制药</a></div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r84365013">.mw-parser-output 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