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class="user-info-component-wrapper"><div class="user-summary-cta-container"><div class="user-summary-container"><div class="social-profile-avatar-container"><img class="profile-avatar u-positionAbsolute" alt="Dominic Trépel" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/24191374/6809598/7687330/s200_dominic.trepel.jpg" /></div><div class="title-container"><h1 class="ds2-5-heading-sans-serif-sm">Dominic Trépel</h1><div class="affiliations-container fake-truncate js-profile-affiliations"><div><a class="u-tcGrayDarker" href="https://leeds.academia.edu/">University of Leeds</a>, <a class="u-tcGrayDarker" href="https://leeds.academia.edu/Departments/Leeds_Institute_of_Health_Sciences/Documents">Leeds Institute of Health Sciences</a>, <span class="u-tcGrayDarker">Faculty Member</span></div><div><a class="u-tcGrayDarker" 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backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Dominic Trépel</h3></div><div class="js-work-strip profile--work_container" data-work-id="27333919"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/27333919/An_examination_of_the_nutritional_intake_and_anthropometric_status_of_individuals_with_intellectual_disabilities_Results_from_the_SOPHIE_study"><img alt="Research paper thumbnail of An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study" class="work-thumbnail" src="https://attachments.academia-assets.com/47589878/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/27333919/An_examination_of_the_nutritional_intake_and_anthropometric_status_of_individuals_with_intellectual_disabilities_Results_from_the_SOPHIE_study">An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://dcu.academia.edu/Deirdrecorby">Deirdre Corby</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PeterGriffin39">Peter Griffin</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The prevalence of obesity appears greater in people with intellectual disabilities than those in ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The prevalence of obesity appears greater in people with intellectual disabilities than those in the general population. This study aimed to examine the nutritional intake and anthropometric status of individuals with intellectual disabilities. Participants aged 16–64 years were recruited from intellectual disability service provider organizations (n ¼ 131). Data were collected using questionnaires ; 4-day food dairies and weight, height and waist circumference measurements. Parti-cipants' mean body mass index (BMI) was 29.4 kg/m 2 + 6.1, 2.4% were underweight, 22.6% were normal weight, 28.2% were overweight and 46.8% were obese. Having a diagnosis of Down syndrome (p ¼ 0.03) was associated with increasing BMI. Increasing waist circumference was associated</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="243aafe4aa79491df732035f3e79cd41" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":47589878,"asset_id":27333919,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/47589878/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="27333919"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="27333919"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 27333919; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=27333919]").text(description); $(".js-view-count[data-work-id=27333919]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 27333919; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='27333919']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "243aafe4aa79491df732035f3e79cd41" } } $('.js-work-strip[data-work-id=27333919]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":27333919,"title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study","translated_title":"","metadata":{"abstract":"The prevalence of obesity appears greater in people with intellectual disabilities than those in the general population. 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href="https://www.academia.edu/22892484/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis"><img alt="Research paper thumbnail of Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/22892484/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis">Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://yorku.academia.edu/AmandaPerry">Amanda Perry</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/VivienPrior">Vivien Prior</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/Glanville">Julie Glanville</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a></span></div><div class="wp-workCard_item"><span>Health technology assessment (Winchester, England)</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Services have variable practices for identifying and providing interventions for &#39;severe atta...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Services have variable practices for identifying and providing interventions for &#39;severe attachment problems&#39; (disorganised attachment patterns and attachment disorders). Several government reports have highlighted the need for better parenting interventions in at-risk groups. This report was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems (the main review). One supplementary review explored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform health economic aspects of the main review. A total of 29 electronic databases were searched with additional mechanisms for identifying a wide pool of references using the Cochrane methodology. 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} }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="20445593"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/20445593/Screening_for_anxiety_disorders_with_the_GAD_7_and_GAD_2_a_systematic_review_and_diagnostic_metaanalysis"><img alt="Research paper thumbnail of Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis" class="work-thumbnail" src="https://attachments.academia-assets.com/41377550/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/20445593/Screening_for_anxiety_disorders_with_the_GAD_7_and_GAD_2_a_systematic_review_and_diagnostic_metaanalysis">Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PlummerFaye">Faye Plummer</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ManeaL">Laura Manea</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identifying anxiety disorders. Methods: A systematic review of the literature was conducted to identify studies that validated the GAD-7 or GAD-2 against a recognized gold standard diagnosis. Pooled estimates of diagnostic test accuracy were produced using random-effects bivariate metaanalysis. Heterogeneity was explored using the I 2 statistic. Results: A total of 12 samples were identified involving 5223 participants; 11 samples provided data on the accuracy of the GAD-7 for identifying generalized anxiety disorder (GAD). Pooled sensitivity and specificity values appeared acceptable at a cutoff point of 8 [sensitivity: 0.83 (95% CI 0.71–0.91), specificity: 0.84 (95% CI 0.70–0.92)] although cutoff scores 7–10 also had similar pooled estimates of sensitivity/specificity. Six samples provided data on the accuracy of the GAD-2 for identifying GAD. Pooled sensitivity and specificity values appeared acceptable at a cutoff of 3 [sensitivity: 0.76 (95% CI 0.55–0.89), specificity: 0.81 (95% CI 0.60–0.92)]. Four studies looked at the accuracy of the questionnaires for identifying any anxiety disorder. Conclusions: The GAD-7 had acceptable properties for identifying GAD at cutoff scores 7–10. The GAD-2 had acceptable properties for identifying GAD at a cutoff score of 3. Further validation studies are needed.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5d3bb0b0a9fe37b32f24078f86456090" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":41377550,"asset_id":20445593,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/41377550/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20445593"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20445593"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20445593; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20445593]").text(description); $(".js-view-count[data-work-id=20445593]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20445593; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20445593']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5d3bb0b0a9fe37b32f24078f86456090" } } $('.js-work-strip[data-work-id=20445593]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20445593,"title":"Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis","translated_title":"","metadata":{"abstract":"Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identifying anxiety disorders. Methods: A systematic review of the literature was conducted to identify studies that validated the GAD-7 or GAD-2 against a recognized gold standard diagnosis. Pooled estimates of diagnostic test accuracy were produced using random-effects bivariate metaanalysis. Heterogeneity was explored using the I 2 statistic. Results: A total of 12 samples were identified involving 5223 participants; 11 samples provided data on the accuracy of the GAD-7 for identifying generalized anxiety disorder (GAD). Pooled sensitivity and specificity values appeared acceptable at a cutoff point of 8 [sensitivity: 0.83 (95% CI 0.71–0.91), specificity: 0.84 (95% CI 0.70–0.92)] although cutoff scores 7–10 also had similar pooled estimates of sensitivity/specificity. Six samples provided data on the accuracy of the GAD-2 for identifying GAD. Pooled sensitivity and specificity values appeared acceptable at a cutoff of 3 [sensitivity: 0.76 (95% CI 0.55–0.89), specificity: 0.81 (95% CI 0.60–0.92)]. Four studies looked at the accuracy of the questionnaires for identifying any anxiety disorder. Conclusions: The GAD-7 had acceptable properties for identifying GAD at cutoff scores 7–10. The GAD-2 had acceptable properties for identifying GAD at a cutoff score of 3. Further validation studies are needed.","ai_title_tag":"GAD-7 and GAD-2 in Anxiety Disorder Diagnosis: A Meta-Analysis"},"translated_abstract":"Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identifying anxiety disorders. Methods: A systematic review of the literature was conducted to identify studies that validated the GAD-7 or GAD-2 against a recognized gold standard diagnosis. Pooled estimates of diagnostic test accuracy were produced using random-effects bivariate metaanalysis. Heterogeneity was explored using the I 2 statistic. Results: A total of 12 samples were identified involving 5223 participants; 11 samples provided data on the accuracy of the GAD-7 for identifying generalized anxiety disorder (GAD). Pooled sensitivity and specificity values appeared acceptable at a cutoff point of 8 [sensitivity: 0.83 (95% CI 0.71–0.91), specificity: 0.84 (95% CI 0.70–0.92)] although cutoff scores 7–10 also had similar pooled estimates of sensitivity/specificity. Six samples provided data on the accuracy of the GAD-2 for identifying GAD. Pooled sensitivity and specificity values appeared acceptable at a cutoff of 3 [sensitivity: 0.76 (95% CI 0.55–0.89), specificity: 0.81 (95% CI 0.60–0.92)]. Four studies looked at the accuracy of the questionnaires for identifying any anxiety disorder. Conclusions: The GAD-7 had acceptable properties for identifying GAD at cutoff scores 7–10. The GAD-2 had acceptable properties for identifying GAD at a cutoff score of 3. Further validation studies are needed.","internal_url":"https://www.academia.edu/20445593/Screening_for_anxiety_disorders_with_the_GAD_7_and_GAD_2_a_systematic_review_and_diagnostic_metaanalysis","translated_internal_url":"","created_at":"2016-01-21T15:22:37.919-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":13302783,"work_id":20445593,"tagging_user_id":24191374,"tagged_user_id":42199162,"co_author_invite_id":3118144,"email":"p***p@leeds.ac.uk","display_order":0,"name":"Faye Plummer","title":"Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis"},{"id":13302784,"work_id":20445593,"tagging_user_id":24191374,"tagged_user_id":32190908,"co_author_invite_id":null,"email":"l***a@york.ac.uk","display_order":4194304,"name":"Laura Manea","title":"Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis"},{"id":13302785,"work_id":20445593,"tagging_user_id":24191374,"tagged_user_id":31763798,"co_author_invite_id":null,"email":"d***n@york.ac.uk","display_order":6291456,"name":"Dean McMillan","title":"Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis"}],"downloadable_attachments":[{"id":41377550,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/41377550/thumbnails/1.jpg","file_name":"1-s2.0-S0163834315002406-main.pdf","download_url":"https://www.academia.edu/attachments/41377550/download_file","bulk_download_file_name":"Screening_for_anxiety_disorders_with_the.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/41377550/1-s2.0-S0163834315002406-main-libre.pdf?1453418671=\u0026response-content-disposition=attachment%3B+filename%3DScreening_for_anxiety_disorders_with_the.pdf\u0026Expires=1738613825\u0026Signature=X1Rp195qdJStskPCT9eoRxAjMbk5LdjWWYwS-94xaugQogakuMfhylm5DacWvC4yRZyUzflJnujGxlSF9PJzSYn7yIbiQpmINHiYoVlxmWuVoIaZJY51fan1oFgxjfIbNCQtzhbY7t1bywm6ey8RljoVzlPcof7Xmn26AiR63IQ3EIgnZHdZta-5AH5Zj6HezoxobemE7v89lIQYO6AFHQNA~9LfxwF39RuGJ~CMar-hMBW2LHyZ-XA2KMzdpa~PyLJrYiD4-PRXAF0On02Jj2AL7zn~gWDYsW-PL1GH9weWuu2GZIE1N7ST0vyeLdQcIoxJ7RGgDCveqO45KjsY0A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Screening_for_anxiety_disorders_with_the_GAD_7_and_GAD_2_a_systematic_review_and_diagnostic_metaanalysis","translated_slug":"","page_count":8,"language":"en","content_type":"Work","summary":"Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identifying anxiety disorders. Methods: A systematic review of the literature was conducted to identify studies that validated the GAD-7 or GAD-2 against a recognized gold standard diagnosis. Pooled estimates of diagnostic test accuracy were produced using random-effects bivariate metaanalysis. Heterogeneity was explored using the I 2 statistic. Results: A total of 12 samples were identified involving 5223 participants; 11 samples provided data on the accuracy of the GAD-7 for identifying generalized anxiety disorder (GAD). Pooled sensitivity and specificity values appeared acceptable at a cutoff point of 8 [sensitivity: 0.83 (95% CI 0.71–0.91), specificity: 0.84 (95% CI 0.70–0.92)] although cutoff scores 7–10 also had similar pooled estimates of sensitivity/specificity. Six samples provided data on the accuracy of the GAD-2 for identifying GAD. Pooled sensitivity and specificity values appeared acceptable at a cutoff of 3 [sensitivity: 0.76 (95% CI 0.55–0.89), specificity: 0.81 (95% CI 0.60–0.92)]. Four studies looked at the accuracy of the questionnaires for identifying any anxiety disorder. Conclusions: The GAD-7 had acceptable properties for identifying GAD at cutoff scores 7–10. The GAD-2 had acceptable properties for identifying GAD at a cutoff score of 3. Further validation studies are needed.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":41377550,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/41377550/thumbnails/1.jpg","file_name":"1-s2.0-S0163834315002406-main.pdf","download_url":"https://www.academia.edu/attachments/41377550/download_file","bulk_download_file_name":"Screening_for_anxiety_disorders_with_the.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/41377550/1-s2.0-S0163834315002406-main-libre.pdf?1453418671=\u0026response-content-disposition=attachment%3B+filename%3DScreening_for_anxiety_disorders_with_the.pdf\u0026Expires=1738613825\u0026Signature=X1Rp195qdJStskPCT9eoRxAjMbk5LdjWWYwS-94xaugQogakuMfhylm5DacWvC4yRZyUzflJnujGxlSF9PJzSYn7yIbiQpmINHiYoVlxmWuVoIaZJY51fan1oFgxjfIbNCQtzhbY7t1bywm6ey8RljoVzlPcof7Xmn26AiR63IQ3EIgnZHdZta-5AH5Zj6HezoxobemE7v89lIQYO6AFHQNA~9LfxwF39RuGJ~CMar-hMBW2LHyZ-XA2KMzdpa~PyLJrYiD4-PRXAF0On02Jj2AL7zn~gWDYsW-PL1GH9weWuu2GZIE1N7ST0vyeLdQcIoxJ7RGgDCveqO45KjsY0A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1314,"name":"Anxiety Disorders","url":"https://www.academia.edu/Documents/in/Anxiety_Disorders"},{"id":6482,"name":"Meta-Analysis and Systematic Review","url":"https://www.academia.edu/Documents/in/Meta-Analysis_and_Systematic_Review"},{"id":43363,"name":"Screening","url":"https://www.academia.edu/Documents/in/Screening"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="20445561"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/20445561/The_feasibility_and_acceptability_of_using_the_Mother_Generated_Index_MGI_as_a_Patient_Reported_Outcome_Measure_in_a_randomised_controlled_trial_of_maternity_care_and_SHIP_trial_team"><img alt="Research paper thumbnail of The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team" class="work-thumbnail" src="https://attachments.academia-assets.com/41377522/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/20445561/The_feasibility_and_acceptability_of_using_the_Mother_Generated_Index_MGI_as_a_Patient_Reported_Outcome_Measure_in_a_randomised_controlled_trial_of_maternity_care_and_SHIP_trial_team">The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PeterDiggle">Peter Diggle</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is we...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is well established, but commonly-used PROM item-sets do not necessarily capture what all respondents consider important. Measuring complex constructs is particularly difficult in randomised controlled trials (RCTs). The Mother-Generated Index (MGI) is a validated antenatal and postnatal QoL instrument in which the variables and scores are completely respondent-driven. This paper reports on the feasibility and acceptability of the MGI in an RCT, and compares the resulting variables and QoL scores with more commonly used instruments. Methods: The single-page MGI was included at the end of a ten page questionnaire pack and posted to the RCT participants at baseline (28–32 weeks' gestation) and follow-up (six weeks postnatal). Feasibility and acceptability were assessed by ease of administration, data entry and completion rates. Variables cited by women were analysed thematically. MGI QoL scores were compared with outcomes from the EQ-5D-3 L; Edinburgh Postnatal Depression Scale; Satisfaction With Life Scale; and State Trait Anxiety Inventory.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="098772e5db46604a6ef9385ca35dd840" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":41377522,"asset_id":20445561,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/41377522/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20445561"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20445561"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20445561; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20445561]").text(description); $(".js-view-count[data-work-id=20445561]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20445561; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20445561']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "098772e5db46604a6ef9385ca35dd840" } } $('.js-work-strip[data-work-id=20445561]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20445561,"title":"The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team","translated_title":"","metadata":{"abstract":"Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is well established, but commonly-used PROM item-sets do not necessarily capture what all respondents consider important. Measuring complex constructs is particularly difficult in randomised controlled trials (RCTs). The Mother-Generated Index (MGI) is a validated antenatal and postnatal QoL instrument in which the variables and scores are completely respondent-driven. This paper reports on the feasibility and acceptability of the MGI in an RCT, and compares the resulting variables and QoL scores with more commonly used instruments. Methods: The single-page MGI was included at the end of a ten page questionnaire pack and posted to the RCT participants at baseline (28–32 weeks' gestation) and follow-up (six weeks postnatal). Feasibility and acceptability were assessed by ease of administration, data entry and completion rates. Variables cited by women were analysed thematically. MGI QoL scores were compared with outcomes from the EQ-5D-3 L; Edinburgh Postnatal Depression Scale; Satisfaction With Life Scale; and State Trait Anxiety Inventory.","ai_title_tag":"Feasibility of the Mother-Generated Index in RCTs"},"translated_abstract":"Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is well established, but commonly-used PROM item-sets do not necessarily capture what all respondents consider important. Measuring complex constructs is particularly difficult in randomised controlled trials (RCTs). The Mother-Generated Index (MGI) is a validated antenatal and postnatal QoL instrument in which the variables and scores are completely respondent-driven. This paper reports on the feasibility and acceptability of the MGI in an RCT, and compares the resulting variables and QoL scores with more commonly used instruments. 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This qualitative study, which was part of a large mixed-method study, examined the experiences and perspectives of people with intellectual disability, their families and staff who work with them, about Special Olympics Ireland (SOI). A total of 47 participants (15 athletes, 6 non-athletes, 18 family members and 8 staff members) participated in focus group and individual interviews. Supplemental data, gathered as part of the larger study extracted from open-ended survey questions completed by 97 family members also informed this element. Findings revealed four main themes: impact of participation on athletes, impact of involvement on families, barriers to participation and how to enhance participation rates. Involvement in Special Olympics impacted positively on the quality of life of athletes and families. Enhanced availability of user-friendly information and service accessibility were important drivers identified for enhancing participation rates in Special Olympics.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="998c51bed9728c8ad40151453acdcbe4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":41377483,"asset_id":20445538,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/41377483/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20445538"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20445538"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20445538; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20445538]").text(description); $(".js-view-count[data-work-id=20445538]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20445538; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20445538']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "998c51bed9728c8ad40151453acdcbe4" } } $('.js-work-strip[data-work-id=20445538]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20445538,"title":"People with intellectual disability and their families' perspectives of Special Olympics Ireland: Qualitative findings from the SOPHIE study","translated_title":"","metadata":{"abstract":"Previous research has highlighted that while involvement in Special Olympics can have benefits for athletes and their families, there can also be many barriers to participation. This qualitative study, which was part of a large mixed-method study, examined the experiences and perspectives of people with intellectual disability, their families and staff who work with them, about Special Olympics Ireland (SOI). A total of 47 participants (15 athletes, 6 non-athletes, 18 family members and 8 staff members) participated in focus group and individual interviews. Supplemental data, gathered as part of the larger study extracted from open-ended survey questions completed by 97 family members also informed this element. Findings revealed four main themes: impact of participation on athletes, impact of involvement on families, barriers to participation and how to enhance participation rates. Involvement in Special Olympics impacted positively on the quality of life of athletes and families. 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research has highlighted that while involvement in Special Olympics can have benefits for athletes and their families, there can also be many barriers to participation. This qualitative study, which was part of a large mixed-method study, examined the experiences and perspectives of people with intellectual disability, their families and staff who work with them, about Special Olympics Ireland (SOI). A total of 47 participants (15 athletes, 6 non-athletes, 18 family members and 8 staff members) participated in focus group and individual interviews. Supplemental data, gathered as part of the larger study extracted from open-ended survey questions completed by 97 family members also informed this element. Findings revealed four main themes: impact of participation on athletes, impact of involvement on families, barriers to participation and how to enhance participation rates. Involvement in Special Olympics impacted positively on the quality of life of athletes and families. Enhanced availability of user-friendly information and service accessibility were important drivers identified for enhancing participation rates in Special Olympics.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":41377483,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/41377483/thumbnails/1.jpg","file_name":"Journal_of_Intellectual_Disabilities-2015-Bowers-1744629515617059.pdf","download_url":"https://www.academia.edu/attachments/41377483/download_file","bulk_download_file_name":"People_with_intellectual_disability_and.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/41377483/Journal_of_Intellectual_Disabilities-2015-Bowers-1744629515617059-libre.pdf?1453418367=\u0026response-content-disposition=attachment%3B+filename%3DPeople_with_intellectual_disability_and.pdf\u0026Expires=1738613826\u0026Signature=Spx8WRE1gJvg6NIkSwlvIWB4cflWCr8QK81l7GaCUCyiTF6XFVfOhu9qh1IDxuvwWxYGXwT4zPeIZSg6KGWgFblk5A9LOPbeilBZ7wMjqyIvRG626ChPJHesVTtlzq5eDXc1fKcFafcAwSwQPe-jGL2c4scytiklVwshCYv1rBNoY9zSmZkdXU8Dp6inDDWoznuVYs1SgfMVtAGUlimLFzpWAIj6IMcGjW3DDUV7KhNAPHL0i7RVcJWNs~XnSpY6wIB2VX58OT1KIXxMIvPh0-mwO5YxRR~khUKp54ZTA4pZnw4knhKdCipfZ~gOZk~vxVIOCEalwpIIv5A~U60GUw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":3136,"name":"Qualitative methodology","url":"https://www.academia.edu/Documents/in/Qualitative_methodology"},{"id":8910,"name":"Evaluation","url":"https://www.academia.edu/Documents/in/Evaluation"},{"id":23868,"name":"Intellectual Disability","url":"https://www.academia.edu/Documents/in/Intellectual_Disability"},{"id":61641,"name":"Olympic Games","url":"https://www.academia.edu/Documents/in/Olympic_Games"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="20440571"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/20440571/Social_Stories_to_alleviate_challenging_behaviour_and_social_difficulties_exhibited_by_children_with_autism_spectrum_disorder_in_mainstream_schools_design_of_a_manualised_training_toolkit_and_feasibility_study_for_a_cluster_randomised_controlled_trial_with_nested_qualitative_and_cost_effectiveness"><img alt="Research paper thumbnail of Social Stories to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised controlled trial with nested qualitative and cost-effectiveness" class="work-thumbnail" src="https://attachments.academia-assets.com/41373607/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/20440571/Social_Stories_to_alleviate_challenging_behaviour_and_social_difficulties_exhibited_by_children_with_autism_spectrum_disorder_in_mainstream_schools_design_of_a_manualised_training_toolkit_and_feasibility_study_for_a_cluster_randomised_controlled_trial_with_nested_qualitative_and_cost_effectiveness">Social Stories to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised controlled trial with nested qualitative and cost-effectiveness</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/MarshallDavid1">Marshall David</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background A Social Story™ (Carol Gray) is a child-friendly intervention that is used to give chi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background<br />A Social Story™ (Carol Gray) is a child-friendly intervention that is used to give children with autism spectrum disorders (ASDs) social information in situations where they have social difficulties. Limited evidence mainly using single-case designs suggests that they can reduce anxiety and challenging behaviour.<br />Objectives<br />The objectives were to conduct a systematic review, use this to develop a manualised intervention and run a feasibility trial to inform a fully powered randomised controlled trial (RCT) on their clinical effectiveness and cost-effectiveness in schools.<br />Design<br />This is a three-stage study following the Medical Research Council framework for complex interventions. Specifically, it involved a theoretical phase, a qualitative stage and a feasibility trial stage.<br />Setting<br />Qualitative interviews and focus groups took place in Child and Adolescent Mental Health Service and primary care settings. The feasibility study took place in 37 local mainstream schools.<br />Participants<br />Fifty children (aged 5–15 years) in mainstream school settings with a diagnosis of ASD were entered into the trial. For each child, an associated teacher and parent was also recruited.<br />Interventions<br />The intervention was a goal-setting session followed by a manualised toolkit (including a training session) for creating Social Stories™ for use with school-aged children. The comparator treatment was a goal-setting session followed by an attention control. Both arms received treatment as usual.<br />Main outcome measures<br />Outcomes tested as part of the feasibility study included child- and proxy-completed questionnaires for mental health, quality of life and goal-based outcome measures. Adults additionally completed behaviour diaries and the parental stress index.<br />Results<br />The review found that the research into social stories is predominantly based in the USA, carried out in under-12-year-olds and using single-case designs. Most studies either did not follow established Social Story criteria or did not report if they did. The assessment of effectiveness presents a largely positive picture but is limited by methodological issues. There were no adequate RCTs and insufficient information to assess a number of important sources of potential bias in most studies. A manualised intervention was produced using an iterative process between user focus groups and a writing team, and assessed in the feasibility study. All 50 participant groups were recruited within the study time frame. Two outcome measures, the Social Responsiveness Scale-2 and the custom-made goal-based measure, showed high levels of completion rates and appeared to be capturing social and behaviour skills targeted by the use of Social Stories. Detailed recommendations for a full trial are provided.<br />Limitations<br />Blinding of participants was not feasible. Treatment fidelity was not assessed because of low levels of story return rates.<br />Conclusions<br />The study showed that a fully powered RCT is feasible with an extended geographical footprint. A large amount of data and information has helped to inform the design of this RCT, which will be the subject of a future research grant application. Future work could focus on developing an appropriate blinded outcome measure for this population.<br />Study registration<br />This study is registered as PROSPERO CRD42011001440.<br />Trial registration<br />Current Controlled Trials ISRCTN96286707.<br />Funding<br />This project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 6. See the NIHR Journals Library website for further project information.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4ff1a63e8bf0a54de098a8f74a49e2d5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":41373607,"asset_id":20440571,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/41373607/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20440571"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20440571"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20440571; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20440571]").text(description); $(".js-view-count[data-work-id=20440571]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20440571; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20440571']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4ff1a63e8bf0a54de098a8f74a49e2d5" } } $('.js-work-strip[data-work-id=20440571]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20440571,"title":"Social Stories to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised controlled trial with nested qualitative and cost-effectiveness","translated_title":"","metadata":{"abstract":"Background\nA Social Story™ (Carol Gray) is a child-friendly intervention that is used to give children with autism spectrum disorders (ASDs) social information in situations where they have social difficulties. Limited evidence mainly using single-case designs suggests that they can reduce anxiety and challenging behaviour.\nObjectives\nThe objectives were to conduct a systematic review, use this to develop a manualised intervention and run a feasibility trial to inform a fully powered randomised controlled trial (RCT) on their clinical effectiveness and cost-effectiveness in schools.\nDesign\nThis is a three-stage study following the Medical Research Council framework for complex interventions. Specifically, it involved a theoretical phase, a qualitative stage and a feasibility trial stage.\nSetting\nQualitative interviews and focus groups took place in Child and Adolescent Mental Health Service and primary care settings. The feasibility study took place in 37 local mainstream schools.\nParticipants\nFifty children (aged 5–15 years) in mainstream school settings with a diagnosis of ASD were entered into the trial. For each child, an associated teacher and parent was also recruited.\nInterventions\nThe intervention was a goal-setting session followed by a manualised toolkit (including a training session) for creating Social Stories™ for use with school-aged children. The comparator treatment was a goal-setting session followed by an attention control. Both arms received treatment as usual.\nMain outcome measures\nOutcomes tested as part of the feasibility study included child- and proxy-completed questionnaires for mental health, quality of life and goal-based outcome measures. Adults additionally completed behaviour diaries and the parental stress index.\nResults\nThe review found that the research into social stories is predominantly based in the USA, carried out in under-12-year-olds and using single-case designs. Most studies either did not follow established Social Story criteria or did not report if they did. The assessment of effectiveness presents a largely positive picture but is limited by methodological issues. There were no adequate RCTs and insufficient information to assess a number of important sources of potential bias in most studies. A manualised intervention was produced using an iterative process between user focus groups and a writing team, and assessed in the feasibility study. All 50 participant groups were recruited within the study time frame. Two outcome measures, the Social Responsiveness Scale-2 and the custom-made goal-based measure, showed high levels of completion rates and appeared to be capturing social and behaviour skills targeted by the use of Social Stories. Detailed recommendations for a full trial are provided.\nLimitations\nBlinding of participants was not feasible. Treatment fidelity was not assessed because of low levels of story return rates.\nConclusions\nThe study showed that a fully powered RCT is feasible with an extended geographical footprint. A large amount of data and information has helped to inform the design of this RCT, which will be the subject of a future research grant application. Future work could focus on developing an appropriate blinded outcome measure for this population.\nStudy registration\nThis study is registered as PROSPERO CRD42011001440.\nTrial registration\nCurrent Controlled Trials ISRCTN96286707.\nFunding\nThis project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 6. See the NIHR Journals Library website for further project information."},"translated_abstract":"Background\nA Social Story™ (Carol Gray) is a child-friendly intervention that is used to give children with autism spectrum disorders (ASDs) social information in situations where they have social difficulties. Limited evidence mainly using single-case designs suggests that they can reduce anxiety and challenging behaviour.\nObjectives\nThe objectives were to conduct a systematic review, use this to develop a manualised intervention and run a feasibility trial to inform a fully powered randomised controlled trial (RCT) on their clinical effectiveness and cost-effectiveness in schools.\nDesign\nThis is a three-stage study following the Medical Research Council framework for complex interventions. Specifically, it involved a theoretical phase, a qualitative stage and a feasibility trial stage.\nSetting\nQualitative interviews and focus groups took place in Child and Adolescent Mental Health Service and primary care settings. The feasibility study took place in 37 local mainstream schools.\nParticipants\nFifty children (aged 5–15 years) in mainstream school settings with a diagnosis of ASD were entered into the trial. For each child, an associated teacher and parent was also recruited.\nInterventions\nThe intervention was a goal-setting session followed by a manualised toolkit (including a training session) for creating Social Stories™ for use with school-aged children. The comparator treatment was a goal-setting session followed by an attention control. Both arms received treatment as usual.\nMain outcome measures\nOutcomes tested as part of the feasibility study included child- and proxy-completed questionnaires for mental health, quality of life and goal-based outcome measures. Adults additionally completed behaviour diaries and the parental stress index.\nResults\nThe review found that the research into social stories is predominantly based in the USA, carried out in under-12-year-olds and using single-case designs. Most studies either did not follow established Social Story criteria or did not report if they did. The assessment of effectiveness presents a largely positive picture but is limited by methodological issues. There were no adequate RCTs and insufficient information to assess a number of important sources of potential bias in most studies. A manualised intervention was produced using an iterative process between user focus groups and a writing team, and assessed in the feasibility study. All 50 participant groups were recruited within the study time frame. Two outcome measures, the Social Responsiveness Scale-2 and the custom-made goal-based measure, showed high levels of completion rates and appeared to be capturing social and behaviour skills targeted by the use of Social Stories. Detailed recommendations for a full trial are provided.\nLimitations\nBlinding of participants was not feasible. Treatment fidelity was not assessed because of low levels of story return rates.\nConclusions\nThe study showed that a fully powered RCT is feasible with an extended geographical footprint. A large amount of data and information has helped to inform the design of this RCT, which will be the subject of a future research grant application. Future work could focus on developing an appropriate blinded outcome measure for this population.\nStudy registration\nThis study is registered as PROSPERO CRD42011001440.\nTrial registration\nCurrent Controlled Trials ISRCTN96286707.\nFunding\nThis project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 6. 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Social Story™ (Carol Gray) is a child-friendly intervention that is used to give children with autism spectrum disorders (ASDs) social information in situations where they have social difficulties. Limited evidence mainly using single-case designs suggests that they can reduce anxiety and challenging behaviour.\nObjectives\nThe objectives were to conduct a systematic review, use this to develop a manualised intervention and run a feasibility trial to inform a fully powered randomised controlled trial (RCT) on their clinical effectiveness and cost-effectiveness in schools.\nDesign\nThis is a three-stage study following the Medical Research Council framework for complex interventions. Specifically, it involved a theoretical phase, a qualitative stage and a feasibility trial stage.\nSetting\nQualitative interviews and focus groups took place in Child and Adolescent Mental Health Service and primary care settings. The feasibility study took place in 37 local mainstream schools.\nParticipants\nFifty children (aged 5–15 years) in mainstream school settings with a diagnosis of ASD were entered into the trial. For each child, an associated teacher and parent was also recruited.\nInterventions\nThe intervention was a goal-setting session followed by a manualised toolkit (including a training session) for creating Social Stories™ for use with school-aged children. The comparator treatment was a goal-setting session followed by an attention control. Both arms received treatment as usual.\nMain outcome measures\nOutcomes tested as part of the feasibility study included child- and proxy-completed questionnaires for mental health, quality of life and goal-based outcome measures. Adults additionally completed behaviour diaries and the parental stress index.\nResults\nThe review found that the research into social stories is predominantly based in the USA, carried out in under-12-year-olds and using single-case designs. Most studies either did not follow established Social Story criteria or did not report if they did. The assessment of effectiveness presents a largely positive picture but is limited by methodological issues. There were no adequate RCTs and insufficient information to assess a number of important sources of potential bias in most studies. A manualised intervention was produced using an iterative process between user focus groups and a writing team, and assessed in the feasibility study. All 50 participant groups were recruited within the study time frame. Two outcome measures, the Social Responsiveness Scale-2 and the custom-made goal-based measure, showed high levels of completion rates and appeared to be capturing social and behaviour skills targeted by the use of Social Stories. Detailed recommendations for a full trial are provided.\nLimitations\nBlinding of participants was not feasible. Treatment fidelity was not assessed because of low levels of story return rates.\nConclusions\nThe study showed that a fully powered RCT is feasible with an extended geographical footprint. A large amount of data and information has helped to inform the design of this RCT, which will be the subject of a future research grant application. Future work could focus on developing an appropriate blinded outcome measure for this population.\nStudy registration\nThis study is registered as PROSPERO CRD42011001440.\nTrial registration\nCurrent Controlled Trials ISRCTN96286707.\nFunding\nThis project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 6. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="15629050"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/15629050/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial"><img alt="Research paper thumbnail of Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial" class="work-thumbnail" src="https://attachments.academia-assets.com/43017748/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/15629050/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial">Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SimonGilbody">Simon Gilbody</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://durham.academia.edu/BenAldersonDay">Ben Alderson-Day</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/LisaDyson">Lisa Dyson</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ShehzadAli13">Shehzad Ali</a></span></div><div class="wp-workCard_item"><span>BMJ open</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant med...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computer-administered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). Adolescents aged 12-18 with low mood/depression, (scoring ≥20 on the Mood and Feelings Questionnaire (MFQ)), will be approa...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3b8a17199fabc21726b2ebf02898bada" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":43017748,"asset_id":15629050,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/43017748/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15629050"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15629050"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15629050; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15629050]").text(description); $(".js-view-count[data-work-id=15629050]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15629050; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15629050']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "3b8a17199fabc21726b2ebf02898bada" } } $('.js-work-strip[data-work-id=15629050]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15629050,"title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial","translated_title":"","metadata":{"abstract":"The 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computer-administered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). Adolescents aged 12-18 with low mood/depression, (scoring ≥20 on the Mood and Feelings Questionnaire (MFQ)), will be approa...","ai_title_tag":"CCBT for Adolescent Depression: A Feasibility Trial","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"BMJ open"},"translated_abstract":"The 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computer-administered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). 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Verduyn","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled 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1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computer-administered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). Adolescents aged 12-18 with low mood/depression, (scoring ≥20 on the Mood and Feelings Questionnaire (MFQ)), will be approa...","owner":{"id":34806340,"first_name":"Simon","middle_initials":null,"last_name":"Gilbody","page_name":"SimonGilbody","domain_name":"independent","created_at":"2015-09-12T09:46:20.723-07:00","display_name":"Simon Gilbody","url":"https://independent.academia.edu/SimonGilbody"},"attachments":[{"id":43017748,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/43017748/thumbnails/1.jpg","file_name":"Computerised_cognitive_behaviour_therapy20160224-13490-1epnl6r.pdf","download_url":"https://www.academia.edu/attachments/43017748/download_file","bulk_download_file_name":"Computerised_cognitive_behaviour_therapy.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/43017748/Computerised_cognitive_behaviour_therapy20160224-13490-1epnl6r-libre.pdf?1456335490=\u0026response-content-disposition=attachment%3B+filename%3DComputerised_cognitive_behaviour_therapy.pdf\u0026Expires=1738613826\u0026Signature=TRqCOvhpYL7rNeG5H5LQvKovfp23VAnwlVXkLWhTOXj34QfD70yo55IPBmkBkc8vdlyuyYlFjQ5~jvrQERxC6FicsU6RSa4dXviiwDtqPeAQReoCahq26a3ZidjAvdSmhiFlMjalFzoeBYjPWq5reejxLQdMW8wQKcPTbd-yCFTvmE5fE7tpYTMFTP-Rr9xsk9wDgHrJXfAIdKBv~Irx30Y-c06wI3SO4waFjN7It8UfNCOp~UHTiZQnP6LqWWhQ9s8VBKe-XEzj-oWYLn6nFULjE4N7LikCSoM4WY9YrAuBik70qoPI~EEdbhmNm6v1~D5mlgprauN8WSMzDDwlTQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":37,"name":"Information Systems","url":"https://www.academia.edu/Documents/in/Information_Systems"},{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology"},{"id":230,"name":"Cognitive Behavioral Therapy","url":"https://www.academia.edu/Documents/in/Cognitive_Behavioral_Therapy"},{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"},{"id":633,"name":"Primary Care","url":"https://www.academia.edu/Documents/in/Primary_Care"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":1314,"name":"Anxiety Disorders","url":"https://www.academia.edu/Documents/in/Anxiety_Disorders"},{"id":2240,"name":"Psychotherapy","url":"https://www.academia.edu/Documents/in/Psychotherapy"},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health"},{"id":3217,"name":"Depression","url":"https://www.academia.edu/Documents/in/Depression"},{"id":4387,"name":"Clinical 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href="https://www.academia.edu/14455901/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis"><img alt="Research paper thumbnail of Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis" class="work-thumbnail" src="https://attachments.academia-assets.com/38313392/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14455901/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis">Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/VAllgar">Victoria Allgar</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ManeaL">Laura Manea</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JennyFell">Jenny Fell</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://yorku.academia.edu/AmandaPerry">Amanda Perry</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/VivienPrior">Vivien Prior</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/WhittonClare">Clare Whitton</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background and objectives: Services have variable practices for identifying and providing interve...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background and objectives: Services have variable practices for identifying and providing interventions <br />for ‘severe attachment problems’ (disorganised attachment patterns and attachment disorders). Several <br />government reports have highlighted the need for better parenting interventions in at-risk groups. This <br />report was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting <br />interventions for children with severe attachment problems (the main review). One supplementary review <br />explored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform <br />health economic aspects of the main review. <br />Data sources: A total of 29 electronic databases were searched with additional mechanisms for <br />identifying a wide pool of references using the Cochrane methodology. Examples of databases searched <br />include PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process & Other Non-Indexed <br />Citations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried <br />out between 6 and 12 January 2012. <br />Review methods: Papers identified were screened and data were extracted by two independent <br />reviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were <br />used, including quality assessment of diagnostic accuracy studies – version 2 and the Cochrane risk of bias <br />tool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken. <br />A health economics analysis was conducted. <br />Results: The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting <br />interventions to improve attachment patterns, and one involving children with reactive attachment <br />disorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed <br />statistically significant improvement in disorganised attachment. The interventions saw less disorganised <br />attachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65; <br />p < 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without <br />video feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool <br />demonstrating validity or psychometric data. Only five reported test–retest data. Twenty-six studies <br />reported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach’s alphas were reported <br />in 12 studies for the comparative tests (11 with α > 0.7) and four studies for the reference tests (four with <br />α > 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with <br />another assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment <br />Interview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment <br />disorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference <br />standard, two studies were found with disorganised attachment at baseline, with one finding raised <br />psychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model <br />could not be justifiably populated. This, alongside other findings, informed research priorities. <br />Limitations: There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our <br />health economists for long-term sequelae, yielded a limited number of papers. <br />Conclusions: Maternal sensitivity interventions show good outcomes in at-risk populations, but require <br />further research with complex children. The SSP and RDC for attachment disorders remain the reference <br />standards for identification until more concurrent and predictive validity research is conducted. A birth <br />cohort with sequential attachment measures and outcomes across different domains is recommended with <br />further, methodologically sound randomised controlled intervention trials. The main area identified for <br />future work was a need for good-quality RCTs in at-risk groups such as those entering foster care <br />or adoption. <br />Study registration: This study is registered as PROSPERO CRD42011001395. <br />Funding: The National Institute for Health Research Health Technology Assessment programme. <br />ABSTRACT <br />NIHR Journals Library <a href="http://www.journalslibrary.nihr.ac.uk" rel="nofollow">www.journalslibrary.nihr.ac.uk</a> <br />viii</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ff2afece6df36dad1ff2d47353759f13" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38313392,"asset_id":14455901,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38313392/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14455901"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14455901"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14455901; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14455901]").text(description); $(".js-view-count[data-work-id=14455901]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14455901; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14455901']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ff2afece6df36dad1ff2d47353759f13" } } $('.js-work-strip[data-work-id=14455901]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14455901,"title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis","translated_title":"","metadata":{"abstract":"Background and objectives: Services have variable practices for identifying and providing interventions\r\nfor ‘severe attachment problems’ (disorganised attachment patterns and attachment disorders). Several\r\ngovernment reports have highlighted the need for better parenting interventions in at-risk groups. This\r\nreport was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting\r\ninterventions for children with severe attachment problems (the main review). One supplementary review\r\nexplored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform\r\nhealth economic aspects of the main review.\r\nData sources: A total of 29 electronic databases were searched with additional mechanisms for\r\nidentifying a wide pool of references using the Cochrane methodology. Examples of databases searched\r\ninclude PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process \u0026 Other Non-Indexed\r\nCitations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried\r\nout between 6 and 12 January 2012.\r\nReview methods: Papers identified were screened and data were extracted by two independent\r\nreviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were\r\nused, including quality assessment of diagnostic accuracy studies – version 2 and the Cochrane risk of bias\r\ntool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken.\r\nA health economics analysis was conducted.\r\nResults: The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting\r\ninterventions to improve attachment patterns, and one involving children with reactive attachment\r\ndisorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed\r\nstatistically significant improvement in disorganised attachment. The interventions saw less disorganised\r\nattachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65;\r\np \u003c 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without\r\nvideo feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool\r\ndemonstrating validity or psychometric data. Only five reported test–retest data. Twenty-six studies\r\nreported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach’s alphas were reported\r\nin 12 studies for the comparative tests (11 with α \u003e 0.7) and four studies for the reference tests (four with\r\nα \u003e 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with\r\nanother assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment\r\nInterview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment\r\ndisorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference\r\nstandard, two studies were found with disorganised attachment at baseline, with one finding raised\r\npsychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model\r\ncould not be justifiably populated. This, alongside other findings, informed research priorities.\r\nLimitations: There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our\r\nhealth economists for long-term sequelae, yielded a limited number of papers.\r\nConclusions: Maternal sensitivity interventions show good outcomes in at-risk populations, but require\r\nfurther research with complex children. The SSP and RDC for attachment disorders remain the reference\r\nstandards for identification until more concurrent and predictive validity research is conducted. A birth\r\ncohort with sequential attachment measures and outcomes across different domains is recommended with\r\nfurther, methodologically sound randomised controlled intervention trials. The main area identified for\r\nfuture work was a need for good-quality RCTs in at-risk groups such as those entering foster care\r\nor adoption.\r\nStudy registration: This study is registered as PROSPERO CRD42011001395.\r\nFunding: The National Institute for Health Research Health Technology Assessment programme.\r\nABSTRACT\r\nNIHR Journals Library www.journalslibrary.nihr.ac.uk\r\nviii","ai_title_tag":"Effectiveness of Parenting Interventions for Attachment Issues"},"translated_abstract":"Background and objectives: Services have variable practices for identifying and providing interventions\r\nfor ‘severe attachment problems’ (disorganised attachment patterns and attachment disorders). Several\r\ngovernment reports have highlighted the need for better parenting interventions in at-risk groups. This\r\nreport was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting\r\ninterventions for children with severe attachment problems (the main review). One supplementary review\r\nexplored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform\r\nhealth economic aspects of the main review.\r\nData sources: A total of 29 electronic databases were searched with additional mechanisms for\r\nidentifying a wide pool of references using the Cochrane methodology. Examples of databases searched\r\ninclude PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process \u0026 Other Non-Indexed\r\nCitations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried\r\nout between 6 and 12 January 2012.\r\nReview methods: Papers identified were screened and data were extracted by two independent\r\nreviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were\r\nused, including quality assessment of diagnostic accuracy studies – version 2 and the Cochrane risk of bias\r\ntool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken.\r\nA health economics analysis was conducted.\r\nResults: The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting\r\ninterventions to improve attachment patterns, and one involving children with reactive attachment\r\ndisorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed\r\nstatistically significant improvement in disorganised attachment. The interventions saw less disorganised\r\nattachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65;\r\np \u003c 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without\r\nvideo feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool\r\ndemonstrating validity or psychometric data. Only five reported test–retest data. Twenty-six studies\r\nreported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach’s alphas were reported\r\nin 12 studies for the comparative tests (11 with α \u003e 0.7) and four studies for the reference tests (four with\r\nα \u003e 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with\r\nanother assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment\r\nInterview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment\r\ndisorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference\r\nstandard, two studies were found with disorganised attachment at baseline, with one finding raised\r\npsychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model\r\ncould not be justifiably populated. This, alongside other findings, informed research priorities.\r\nLimitations: There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our\r\nhealth economists for long-term sequelae, yielded a limited number of papers.\r\nConclusions: Maternal sensitivity interventions show good outcomes in at-risk populations, but require\r\nfurther research with complex children. The SSP and RDC for attachment disorders remain the reference\r\nstandards for identification until more concurrent and predictive validity research is conducted. A birth\r\ncohort with sequential attachment measures and outcomes across different domains is recommended with\r\nfurther, methodologically sound randomised controlled intervention trials. The main area identified for\r\nfuture work was a need for good-quality RCTs in at-risk groups such as those entering foster care\r\nor adoption.\r\nStudy registration: This study is registered as PROSPERO CRD42011001395.\r\nFunding: The National Institute for Health Research Health Technology Assessment programme.\r\nABSTRACT\r\nNIHR Journals Library www.journalslibrary.nihr.ac.uk\r\nviii","internal_url":"https://www.academia.edu/14455901/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis","translated_internal_url":"","created_at":"2015-07-28T01:09:55.851-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3957654,"work_id":14455901,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942616,"email":"m***y@nyypct.nhs.uk","display_order":-1,"name":"Barry Melissa (NORTH YORKSHIRE AND YORK PCT)","title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and 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Barry","title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis"},{"id":25297724,"work_id":14455901,"tagging_user_id":32190908,"tagged_user_id":34806340,"co_author_invite_id":null,"email":"s***9@york.ac.uk","display_order":8387584,"name":"Simon Gilbody","title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis"},{"id":31105906,"work_id":14455901,"tagging_user_id":47522776,"tagged_user_id":77830027,"co_author_invite_id":6636249,"email":"c***n@nhs.net","display_order":8388096,"name":"Clare Whitton","title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis"}],"downloadable_attachments":[{"id":38313392,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/38313392/thumbnails/1.jpg","file_name":"FullReport-hta19520.pdf","download_url":"https://www.academia.edu/attachments/38313392/download_file","bulk_download_file_name":"Clinical_effectiveness_and_cost_effectiv.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/38313392/FullReport-hta19520-libre.pdf?1438071201=\u0026response-content-disposition=attachment%3B+filename%3DClinical_effectiveness_and_cost_effectiv.pdf\u0026Expires=1738613826\u0026Signature=F6uma1vwlabcU3Sre4rzB5tIpa0z-PaQ0Q1uvPSZN7e7JNK4FiP7jrlwNoZh7EKtckANUkprJEa9C52KVOWWj-Mh7P4JJn61mQyUvd9QfpIR3l-YjpgbnISqhaMyi-qQ0t8R5sgmDZizGxwcLmGFFrzMlmTbsRonSiDcnR0K2Z6Hui5KXyTrKjS0x7HYaGNJmuqpJmCi02AoYW5oP4d3wbjgo8z8cy81RJ0GprbllbUYXN8s3Sppqvdjiu6ET7LU-wJxKK-Mc777vFXn0dyeatgeaAdSe23~xBo4UpHA7tdAQjYkbPpZHE4r6WCDIGiP4Q~kglah2bbldf2iONPgeQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis","translated_slug":"","page_count":380,"language":"en","content_type":"Work","summary":"Background and objectives: Services have variable practices for identifying and providing interventions\r\nfor ‘severe attachment problems’ (disorganised attachment patterns and attachment disorders). Several\r\ngovernment reports have highlighted the need for better parenting interventions in at-risk groups. This\r\nreport was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting\r\ninterventions for children with severe attachment problems (the main review). One supplementary review\r\nexplored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform\r\nhealth economic aspects of the main review.\r\nData sources: A total of 29 electronic databases were searched with additional mechanisms for\r\nidentifying a wide pool of references using the Cochrane methodology. Examples of databases searched\r\ninclude PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process \u0026 Other Non-Indexed\r\nCitations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried\r\nout between 6 and 12 January 2012.\r\nReview methods: Papers identified were screened and data were extracted by two independent\r\nreviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were\r\nused, including quality assessment of diagnostic accuracy studies – version 2 and the Cochrane risk of bias\r\ntool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken.\r\nA health economics analysis was conducted.\r\nResults: The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting\r\ninterventions to improve attachment patterns, and one involving children with reactive attachment\r\ndisorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed\r\nstatistically significant improvement in disorganised attachment. The interventions saw less disorganised\r\nattachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65;\r\np \u003c 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without\r\nvideo feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool\r\ndemonstrating validity or psychometric data. Only five reported test–retest data. Twenty-six studies\r\nreported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach’s alphas were reported\r\nin 12 studies for the comparative tests (11 with α \u003e 0.7) and four studies for the reference tests (four with\r\nα \u003e 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with\r\nanother assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment\r\nInterview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment\r\ndisorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference\r\nstandard, two studies were found with disorganised attachment at baseline, with one finding raised\r\npsychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model\r\ncould not be justifiably populated. This, alongside other findings, informed research priorities.\r\nLimitations: There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our\r\nhealth economists for long-term sequelae, yielded a limited number of papers.\r\nConclusions: Maternal sensitivity interventions show good outcomes in at-risk populations, but require\r\nfurther research with complex children. The SSP and RDC for attachment disorders remain the reference\r\nstandards for identification until more concurrent and predictive validity research is conducted. A birth\r\ncohort with sequential attachment measures and outcomes across different domains is recommended with\r\nfurther, methodologically sound randomised controlled intervention trials. The main area identified for\r\nfuture work was a need for good-quality RCTs in at-risk groups such as those entering foster care\r\nor adoption.\r\nStudy registration: This study is registered as PROSPERO CRD42011001395.\r\nFunding: The National Institute for Health Research Health Technology Assessment programme.\r\nABSTRACT\r\nNIHR Journals Library www.journalslibrary.nihr.ac.uk\r\nviii","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":38313392,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/38313392/thumbnails/1.jpg","file_name":"FullReport-hta19520.pdf","download_url":"https://www.academia.edu/attachments/38313392/download_file","bulk_download_file_name":"Clinical_effectiveness_and_cost_effectiv.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/38313392/FullReport-hta19520-libre.pdf?1438071201=\u0026response-content-disposition=attachment%3B+filename%3DClinical_effectiveness_and_cost_effectiv.pdf\u0026Expires=1738613826\u0026Signature=F6uma1vwlabcU3Sre4rzB5tIpa0z-PaQ0Q1uvPSZN7e7JNK4FiP7jrlwNoZh7EKtckANUkprJEa9C52KVOWWj-Mh7P4JJn61mQyUvd9QfpIR3l-YjpgbnISqhaMyi-qQ0t8R5sgmDZizGxwcLmGFFrzMlmTbsRonSiDcnR0K2Z6Hui5KXyTrKjS0x7HYaGNJmuqpJmCi02AoYW5oP4d3wbjgo8z8cy81RJ0GprbllbUYXN8s3Sppqvdjiu6ET7LU-wJxKK-Mc777vFXn0dyeatgeaAdSe23~xBo4UpHA7tdAQjYkbPpZHE4r6WCDIGiP4Q~kglah2bbldf2iONPgeQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":724,"name":"Economics","url":"https://www.academia.edu/Documents/in/Economics"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":6482,"name":"Meta-Analysis and Systematic Review","url":"https://www.academia.edu/Documents/in/Meta-Analysis_and_Systematic_Review"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":16834,"name":"Attachment Theory","url":"https://www.academia.edu/Documents/in/Attachment_Theory"}],"urls":[{"id":5019605,"url":"http://www.journalslibrary.nihr.ac.uk/hta/volume-19/issue-52#abstract"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="13085101"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/13085101/Autism_Spectrum_Social_Stories_In_Schools_Trial_ASSSIST_study_protocol_for_a_feasibility_randomised_controlled_trial_analysing_clinical_and_cost_effectiveness_of_Social_Stories_in_mainstream_schools"><img alt="Research paper thumbnail of Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost effectiveness of Social Stories in mainstream schools" class="work-thumbnail" src="https://attachments.academia-assets.com/37940494/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/13085101/Autism_Spectrum_Social_Stories_In_Schools_Trial_ASSSIST_study_protocol_for_a_feasibility_randomised_controlled_trial_analysing_clinical_and_cost_effectiveness_of_Social_Stories_in_mainstream_schools">Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost effectiveness of Social Stories in mainstream schools</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/LizCook">Liz Cook</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HannahAinsworth">Hannah Ainsworth</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/JoyAdamson">Joy Adamson</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/LisaDyson">Lisa Dyson</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/VAllgar">Victoria Allgar</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction Current evidence suggests that Social Stories can be effective in tackling problem b...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction Current evidence suggests that Social Stories can be effective in tackling problem behaviours exhibited by children with autism spectrum disorder. Exploring the meaning of behaviour from a child's perspective allows stories to provide social information that is tailored to their needs. Case reports in children with autism have suggested that these stories can lead to a number of benefits including improvements in social interactions and choice making in educational settings. <br /> <br />Methods and analysis The feasibility of clinical and cost-effectiveness of a Social Stories toolkit will be assessed using a randomised control framework. Participants (n=50) will be randomised to either the Social Stories intervention or a comparator group where they will be read standard stories for an equivalent amount of time. Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. Qualitative analysis will ascertain information on perceptions about the feasibility and acceptability of the intervention. <br /> <br />Ethics and dissemination National Health Service Ethics Approval (NHS; ref 11/YH/0340) for the trial protocol has been obtained along with NHS Research and Development permission from Leeds and York Partnership NHS Foundation Trust. All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. At least one article in a peer reviewed journal will be published and research findings presented at relevant conferences. <br /> <br />Trial registration number ISRCTN96286707.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2ec052029ebfcac5751c60a01e44ee37" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37940494,"asset_id":13085101,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37940494/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="13085101"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="13085101"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13085101; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13085101]").text(description); $(".js-view-count[data-work-id=13085101]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13085101; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='13085101']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2ec052029ebfcac5751c60a01e44ee37" } } $('.js-work-strip[data-work-id=13085101]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":13085101,"title":"Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost effectiveness of Social Stories in mainstream schools","translated_title":"","metadata":{"abstract":"Introduction Current evidence suggests that Social Stories can be effective in tackling problem behaviours exhibited by children with autism spectrum disorder. Exploring the meaning of behaviour from a child's perspective allows stories to provide social information that is tailored to their needs. Case reports in children with autism have suggested that these stories can lead to a number of benefits including improvements in social interactions and choice making in educational settings.\r\n\r\nMethods and analysis The feasibility of clinical and cost-effectiveness of a Social Stories toolkit will be assessed using a randomised control framework. Participants (n=50) will be randomised to either the Social Stories intervention or a comparator group where they will be read standard stories for an equivalent amount of time. Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. Qualitative analysis will ascertain information on perceptions about the feasibility and acceptability of the intervention.\r\n\r\nEthics and dissemination National Health Service Ethics Approval (NHS; ref 11/YH/0340) for the trial protocol has been obtained along with NHS Research and Development permission from Leeds and York Partnership NHS Foundation Trust. All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. At least one article in a peer reviewed journal will be published and research findings presented at relevant conferences.\r\n\r\nTrial registration number ISRCTN96286707."},"translated_abstract":"Introduction Current evidence suggests that Social Stories can be effective in tackling problem behaviours exhibited by children with autism spectrum disorder. Exploring the meaning of behaviour from a child's perspective allows stories to provide social information that is tailored to their needs. Case reports in children with autism have suggested that these stories can lead to a number of benefits including improvements in social interactions and choice making in educational settings.\r\n\r\nMethods and analysis The feasibility of clinical and cost-effectiveness of a Social Stories toolkit will be assessed using a randomised control framework. Participants (n=50) will be randomised to either the Social Stories intervention or a comparator group where they will be read standard stories for an equivalent amount of time. Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. Qualitative analysis will ascertain information on perceptions about the feasibility and acceptability of the intervention.\r\n\r\nEthics and dissemination National Health Service Ethics Approval (NHS; ref 11/YH/0340) for the trial protocol has been obtained along with NHS Research and Development permission from Leeds and York Partnership NHS Foundation Trust. All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. At least one article in a peer reviewed journal will be published and research findings presented at relevant conferences.\r\n\r\nTrial registration number ISRCTN96286707.","internal_url":"https://www.academia.edu/13085101/Autism_Spectrum_Social_Stories_In_Schools_Trial_ASSSIST_study_protocol_for_a_feasibility_randomised_controlled_trial_analysing_clinical_and_cost_effectiveness_of_Social_Stories_in_mainstream_schools","translated_internal_url":"","created_at":"2015-06-18T13:37:35.504-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3957400,"work_id":13085101,"tagging_user_id":24191374,"tagged_user_id":33557333,"co_author_invite_id":942569,"email":"l***k@york.ac.uk","affiliation":"University of York","display_order":-1,"name":"Liz Cook","title":"Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled 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Current evidence suggests that Social Stories can be effective in tackling problem behaviours exhibited by children with autism spectrum disorder. Exploring the meaning of behaviour from a child's perspective allows stories to provide social information that is tailored to their needs. Case reports in children with autism have suggested that these stories can lead to a number of benefits including improvements in social interactions and choice making in educational settings.\r\n\r\nMethods and analysis The feasibility of clinical and cost-effectiveness of a Social Stories toolkit will be assessed using a randomised control framework. Participants (n=50) will be randomised to either the Social Stories intervention or a comparator group where they will be read standard stories for an equivalent amount of time. Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. Qualitative analysis will ascertain information on perceptions about the feasibility and acceptability of the intervention.\r\n\r\nEthics and dissemination National Health Service Ethics Approval (NHS; ref 11/YH/0340) for the trial protocol has been obtained along with NHS Research and Development permission from Leeds and York Partnership NHS Foundation Trust. All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. At least one article in a peer reviewed journal will be published and research findings presented at relevant conferences.\r\n\r\nTrial registration number ISRCTN96286707.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":37940494,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940494/thumbnails/1.jpg","file_name":"BMJ_Open-2014-Wright-1.pdf","download_url":"https://www.academia.edu/attachments/37940494/download_file","bulk_download_file_name":"Autism_Spectrum_Social_Stories_In_School.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940494/BMJ_Open-2014-Wright-1-libre.pdf?1434660060=\u0026response-content-disposition=attachment%3B+filename%3DAutism_Spectrum_Social_Stories_In_School.pdf\u0026Expires=1738613826\u0026Signature=Va651t8m5Mme2~RpMB~5bDyn85sf227S8njJLLSANy5~Rla7zzEmdE6kT0OZqthpsXevqJ9HIQZEGRcDx8UOOY7YyEj3yjHmJfLnzUEZyXVcLGxOWU9EZB81jg9XPSpsH5gBuUhnRAMgYcUx3o-vjfFV6ZuNXBQfqCUazn-~ZkjChXnqtplVkePCgSRkYSvOQRnOZMKDlDsbs0G2mgt~EWjUWOmVSwvIKXlZl9WlukVPwTaLOqM7r0a7RWWDp8xx4Y7rR-ELA9YS6u-vrG9N~a6xk2Oo9-ZVRQQNrKJaYcRdK52UUo5~ipClVQdAYzRklQiMHzduIIiD8PddwXafgQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":2249,"name":"Autism","url":"https://www.academia.edu/Documents/in/Autism"},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health"},{"id":4270,"name":"Autism Spectrum Disorders","url":"https://www.academia.edu/Documents/in/Autism_Spectrum_Disorders"},{"id":4387,"name":"Clinical Trials","url":"https://www.academia.edu/Documents/in/Clinical_Trials"},{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":23550,"name":"Autism (Education)","url":"https://www.academia.edu/Documents/in/Autism_Education_"},{"id":44526,"name":"Feasibility Study","url":"https://www.academia.edu/Documents/in/Feasibility_Study"},{"id":1223929,"name":"Autism Spectrum Treatment","url":"https://www.academia.edu/Documents/in/Autism_Spectrum_Treatment"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="13084982"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/13084982/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial"><img alt="Research paper thumbnail of Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial" class="work-thumbnail" src="https://attachments.academia-assets.com/37940478/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/13084982/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial">Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/JoyAdamson">Joy Adamson</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/VAllgar">Victoria Allgar</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/LisaDyson">Lisa Dyson</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: The 1 year prevalence of depression in adolescents is about 2%. Treatment with ant...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: The 1 year prevalence of depression in <br />adolescents is about 2%. Treatment with antidepressant <br />medication is not recommended for initial treatment in <br />young people due to concerns over high side effects, <br />poor efficacy and addictive potential. Evidence suggests <br />that cognitive behaviour therapy (CBT) is an effective <br />treatment for depression and is currently one of the <br />main treatment options recommended in adolescents. <br />Given the affinity young people have with information <br />technology they may be treated effectively, more widely <br />and earlier in their illness evolution using computeradministered <br />CBT (CCBT). Currently little is known <br />about the clinical and resource implications of <br />implementing CCBT within the National Health Service <br />for adolescents with low mood/depression. We aim to <br />establish the feasibility of running a fully powered <br />randomised controlled trial (RCT). <br />Methods and analysis: Adolescents aged 12–18 with <br />low mood/depression, (scoring ≥20 on the Mood and <br />Feelings Questionnaire (MFQ)), will be approached to <br />participate. Consenting participants will be randomised <br />to either a CCBT programme (Stressbusters) or <br />accessing selected websites providing information <br />about low mood/depression. The primary outcome <br />measure will be the Beck Depression Inventory (BDI). <br />Participants will also complete generic health measures <br />(EQ5D-Y, HUI2) and resource use questionnaires to <br />examine the feasibility of cost-effectiveness analysis. <br />Questionnaires will be completed at baseline, 4 and 12- <br />month follow-ups. Progress and risk will be monitored <br />via the MFQ administered at each treatment session. <br />The acceptability of a CCBT programme to adolescents; <br />and the willingness of clinicians to recruit participants <br />and of participants to be randomised, recruitment rates, <br />attrition rates and questionnaire completion rates will be <br />collected for feasibility analysis. We will estimate <br />‘numbers needed’ to plan a fully powered RCT of clinical <br />and cost-effectiveness. <br />Ethics and dissemination: The current trial protocol <br />received a favourable ethical opinion from Leeds <br />(West) Research and Ethics Committee. (Reference: <br />10/H1307/137). <br />Trial registration number: ISRCTN31219579.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6e6366e2ba9c5c87cf6af4ec05e18db0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37940478,"asset_id":13084982,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37940478/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="13084982"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="13084982"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13084982; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13084982]").text(description); $(".js-view-count[data-work-id=13084982]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13084982; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='13084982']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6e6366e2ba9c5c87cf6af4ec05e18db0" } } $('.js-work-strip[data-work-id=13084982]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":13084982,"title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial","translated_title":"","metadata":{"abstract":"Introduction: The 1 year prevalence of depression in\r\nadolescents is about 2%. Treatment with antidepressant\r\nmedication is not recommended for initial treatment in\r\nyoung people due to concerns over high side effects,\r\npoor efficacy and addictive potential. Evidence suggests\r\nthat cognitive behaviour therapy (CBT) is an effective\r\ntreatment for depression and is currently one of the\r\nmain treatment options recommended in adolescents.\r\nGiven the affinity young people have with information\r\ntechnology they may be treated effectively, more widely\r\nand earlier in their illness evolution using computeradministered\r\nCBT (CCBT). Currently little is known\r\nabout the clinical and resource implications of\r\nimplementing CCBT within the National Health Service\r\nfor adolescents with low mood/depression. We aim to\r\nestablish the feasibility of running a fully powered\r\nrandomised controlled trial (RCT).\r\nMethods and analysis: Adolescents aged 12–18 with\r\nlow mood/depression, (scoring ≥20 on the Mood and\r\nFeelings Questionnaire (MFQ)), will be approached to\r\nparticipate. Consenting participants will be randomised\r\nto either a CCBT programme (Stressbusters) or\r\naccessing selected websites providing information\r\nabout low mood/depression. The primary outcome\r\nmeasure will be the Beck Depression Inventory (BDI).\r\nParticipants will also complete generic health measures\r\n(EQ5D-Y, HUI2) and resource use questionnaires to\r\nexamine the feasibility of cost-effectiveness analysis.\r\nQuestionnaires will be completed at baseline, 4 and 12-\r\nmonth follow-ups. Progress and risk will be monitored\r\nvia the MFQ administered at each treatment session.\r\nThe acceptability of a CCBT programme to adolescents;\r\nand the willingness of clinicians to recruit participants\r\nand of participants to be randomised, recruitment rates,\r\nattrition rates and questionnaire completion rates will be\r\ncollected for feasibility analysis. We will estimate\r\n‘numbers needed’ to plan a fully powered RCT of clinical\r\nand cost-effectiveness.\r\nEthics and dissemination: The current trial protocol\r\nreceived a favourable ethical opinion from Leeds\r\n(West) Research and Ethics Committee. (Reference:\r\n10/H1307/137).\r\nTrial registration number: ISRCTN31219579."},"translated_abstract":"Introduction: The 1 year prevalence of depression in\r\nadolescents is about 2%. Treatment with antidepressant\r\nmedication is not recommended for initial treatment in\r\nyoung people due to concerns over high side effects,\r\npoor efficacy and addictive potential. Evidence suggests\r\nthat cognitive behaviour therapy (CBT) is an effective\r\ntreatment for depression and is currently one of the\r\nmain treatment options recommended in adolescents.\r\nGiven the affinity young people have with information\r\ntechnology they may be treated effectively, more widely\r\nand earlier in their illness evolution using computeradministered\r\nCBT (CCBT). Currently little is known\r\nabout the clinical and resource implications of\r\nimplementing CCBT within the National Health Service\r\nfor adolescents with low mood/depression. We aim to\r\nestablish the feasibility of running a fully powered\r\nrandomised controlled trial (RCT).\r\nMethods and analysis: Adolescents aged 12–18 with\r\nlow mood/depression, (scoring ≥20 on the Mood and\r\nFeelings Questionnaire (MFQ)), will be approached to\r\nparticipate. Consenting participants will be randomised\r\nto either a CCBT programme (Stressbusters) or\r\naccessing selected websites providing information\r\nabout low mood/depression. The primary outcome\r\nmeasure will be the Beck Depression Inventory (BDI).\r\nParticipants will also complete generic health measures\r\n(EQ5D-Y, HUI2) and resource use questionnaires to\r\nexamine the feasibility of cost-effectiveness analysis.\r\nQuestionnaires will be completed at baseline, 4 and 12-\r\nmonth follow-ups. Progress and risk will be monitored\r\nvia the MFQ administered at each treatment session.\r\nThe acceptability of a CCBT programme to adolescents;\r\nand the willingness of clinicians to recruit participants\r\nand of participants to be randomised, recruitment rates,\r\nattrition rates and questionnaire completion rates will be\r\ncollected for feasibility analysis. We will estimate\r\n‘numbers needed’ to plan a fully powered RCT of clinical\r\nand cost-effectiveness.\r\nEthics and dissemination: The current trial protocol\r\nreceived a favourable ethical opinion from Leeds\r\n(West) Research and Ethics Committee. (Reference:\r\n10/H1307/137).\r\nTrial registration number: ISRCTN31219579.","internal_url":"https://www.academia.edu/13084982/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial","translated_internal_url":"","created_at":"2015-06-18T13:34:33.335-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3957458,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942581,"email":"s***y@hyms.ac.uk","display_order":-1,"name":"Simon Gilbody","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957459,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":333911,"email":"b***y@sms.ed.ac.uk","display_order":1,"name":"Ben Alderson-Day","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957460,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":827509,"co_author_invite_id":null,"email":"b***y@durham.ac.uk","affiliation":"Durham University","display_order":2,"name":"Ben Alderson-Day","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957765,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":324119,"email":"b***t@nyypct.nhs.uk","display_order":3,"name":"Barry Wright","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957766,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942646,"email":"l***l@nyypct.nhs.uk","display_order":4,"name":"Lucy Tindall","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957767,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":33444225,"co_author_invite_id":537027,"email":"j***n@york.ac.uk","affiliation":"University of York","display_order":5,"name":"Joy Adamson","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957768,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":33441087,"co_author_invite_id":366100,"email":"v***r@hyms.ac.uk","affiliation":"University of York","display_order":6,"name":"Victoria Allgar","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957769,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":333914,"email":"s***0@ucl.ac.uk","display_order":7,"name":"Sophie Bennett","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957771,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942647,"email":"c***n@cmmc.nhs.uk","display_order":8,"name":"Chrissie Verduyn","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957772,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":35884351,"co_author_invite_id":648697,"email":"l***n@york.ac.uk","affiliation":"University of York","display_order":9,"name":"Lisa Dyson","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957773,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942643,"email":"s***0@york.ac.uk","display_order":10,"name":"Shehzad Ali","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":32049411,"work_id":13084982,"tagging_user_id":33441087,"tagged_user_id":11797,"co_author_invite_id":null,"email":"e***r@sheffield.ac.uk","affiliation":"The University of Sheffield","display_order":4194309,"name":"Eva Kaltenthaler","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"}],"downloadable_attachments":[{"id":37940478,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940478/thumbnails/1.jpg","file_name":"BMJ_Open-2014-Wright-.pdf","download_url":"https://www.academia.edu/attachments/37940478/download_file","bulk_download_file_name":"Computerised_cognitive_behaviour_therapy.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940478/BMJ_Open-2014-Wright--libre.pdf?1434659857=\u0026response-content-disposition=attachment%3B+filename%3DComputerised_cognitive_behaviour_therapy.pdf\u0026Expires=1738613826\u0026Signature=XmzrGyCsoj3s2B5fJQJCzXOlGzEMY9C0gvm2aoSoNiEqgRuVzcn06ESP9-~QHzl6tz9cADQbINLPUOp~VhYv7k36gvDVVZgSvAkvegvSgQ46VWDZqNQWh3d3IA0D22MeRuQfRM6CbsL7hQdwSm4oJycR-1rZOR7ytbE-dhBvD5G4eUAGGFSja-cZqwWMiVQ3ZcS5lOXWh-Gdjeocct47WzMj4riTjcwBMVgti0y8JoWFijANobaceuPYfQrwz9sibWXI8xXPGI4n7IKKChDJhLJLM2F3PG4LD2Qj1bwgbIodVK5K0i2hbppZNAUY~pkc5VIIhJwB3T2NSJvnejzT8A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial","translated_slug":"","page_count":9,"language":"en","content_type":"Work","summary":"Introduction: The 1 year prevalence of depression in\r\nadolescents is about 2%. Treatment with antidepressant\r\nmedication is not recommended for initial treatment in\r\nyoung people due to concerns over high side effects,\r\npoor efficacy and addictive potential. Evidence suggests\r\nthat cognitive behaviour therapy (CBT) is an effective\r\ntreatment for depression and is currently one of the\r\nmain treatment options recommended in adolescents.\r\nGiven the affinity young people have with information\r\ntechnology they may be treated effectively, more widely\r\nand earlier in their illness evolution using computeradministered\r\nCBT (CCBT). Currently little is known\r\nabout the clinical and resource implications of\r\nimplementing CCBT within the National Health Service\r\nfor adolescents with low mood/depression. We aim to\r\nestablish the feasibility of running a fully powered\r\nrandomised controlled trial (RCT).\r\nMethods and analysis: Adolescents aged 12–18 with\r\nlow mood/depression, (scoring ≥20 on the Mood and\r\nFeelings Questionnaire (MFQ)), will be approached to\r\nparticipate. Consenting participants will be randomised\r\nto either a CCBT programme (Stressbusters) or\r\naccessing selected websites providing information\r\nabout low mood/depression. The primary outcome\r\nmeasure will be the Beck Depression Inventory (BDI).\r\nParticipants will also complete generic health measures\r\n(EQ5D-Y, HUI2) and resource use questionnaires to\r\nexamine the feasibility of cost-effectiveness analysis.\r\nQuestionnaires will be completed at baseline, 4 and 12-\r\nmonth follow-ups. Progress and risk will be monitored\r\nvia the MFQ administered at each treatment session.\r\nThe acceptability of a CCBT programme to adolescents;\r\nand the willingness of clinicians to recruit participants\r\nand of participants to be randomised, recruitment rates,\r\nattrition rates and questionnaire completion rates will be\r\ncollected for feasibility analysis. We will estimate\r\n‘numbers needed’ to plan a fully powered RCT of clinical\r\nand cost-effectiveness.\r\nEthics and dissemination: The current trial protocol\r\nreceived a favourable ethical opinion from Leeds\r\n(West) Research and Ethics Committee. (Reference:\r\n10/H1307/137).\r\nTrial registration number: ISRCTN31219579.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":37940478,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940478/thumbnails/1.jpg","file_name":"BMJ_Open-2014-Wright-.pdf","download_url":"https://www.academia.edu/attachments/37940478/download_file","bulk_download_file_name":"Computerised_cognitive_behaviour_therapy.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940478/BMJ_Open-2014-Wright--libre.pdf?1434659857=\u0026response-content-disposition=attachment%3B+filename%3DComputerised_cognitive_behaviour_therapy.pdf\u0026Expires=1738613826\u0026Signature=XmzrGyCsoj3s2B5fJQJCzXOlGzEMY9C0gvm2aoSoNiEqgRuVzcn06ESP9-~QHzl6tz9cADQbINLPUOp~VhYv7k36gvDVVZgSvAkvegvSgQ46VWDZqNQWh3d3IA0D22MeRuQfRM6CbsL7hQdwSm4oJycR-1rZOR7ytbE-dhBvD5G4eUAGGFSja-cZqwWMiVQ3ZcS5lOXWh-Gdjeocct47WzMj4riTjcwBMVgti0y8JoWFijANobaceuPYfQrwz9sibWXI8xXPGI4n7IKKChDJhLJLM2F3PG4LD2Qj1bwgbIodVK5K0i2hbppZNAUY~pkc5VIIhJwB3T2NSJvnejzT8A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":230,"name":"Cognitive Behavioral Therapy","url":"https://www.academia.edu/Documents/in/Cognitive_Behavioral_Therapy"},{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health"},{"id":4387,"name":"Clinical Trials","url":"https://www.academia.edu/Documents/in/Clinical_Trials"},{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":44526,"name":"Feasibility Study","url":"https://www.academia.edu/Documents/in/Feasibility_Study"},{"id":65944,"name":"eHealth","url":"https://www.academia.edu/Documents/in/eHealth"},{"id":189859,"name":"eHealth, health informatics, Healthcare Technology","url":"https://www.academia.edu/Documents/in/eHealth_health_informatics_Healthcare_Technology"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="13084418"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/13084418/Self_hypnosis_for_intrapartum_pain_management_in_pregnant_nulliparous_women_a_randomised_controlled_trial_of_clinical_effectiveness"><img alt="Research paper thumbnail of Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness" class="work-thumbnail" src="https://attachments.academia-assets.com/37940367/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/13084418/Self_hypnosis_for_intrapartum_pain_management_in_pregnant_nulliparous_women_a_randomised_controlled_trial_of_clinical_effectiveness">Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://uclan.academia.edu/SooDowne">Soo Downe</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/FinlaysonK">K. Finlayson</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HSpiby">H. Spiby</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HinderS">S. Hinder</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Abstract OBJECTIVE: (Primary) To establish the effect of antenatal group self-hypnosis for null...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Abstract <br />OBJECTIVE: <br />(Primary) To establish the effect of antenatal group self-hypnosis for nulliparous women on intra-partum epidural use. <br />DESIGN: <br />Multi-method randomised control trial (RCT). <br />SETTING: <br />Three NHS Trusts. <br />POPULATION: <br />Nulliparous women not planning elective caesarean, without medication for hypertension and without psychological illness. <br />METHODS: <br />Randomisation at 28-32 weeks' gestation to usual care, or to usual care plus brief self-hypnosis training (two × 90-minute groups at around 32 and 35 weeks' gestation; daily audio self-hypnosis CD). Follow up at 2 and 6 weeks postnatal. <br />MAIN OUTCOME MEASURES: <br />Primary: epidural analgesia. Secondary: associated clinical and psychological outcomes; cost analysis. <br />RESULTS: <br />Six hundred and eighty women were randomised. There was no statistically significant difference in epidural use: 27.9% (intervention), 30.3% (control), odds ratio (OR) 0.89 [95% confidence interval (CI): 0.64-1.24], or in 27 of 29 pre-specified secondary clinical and psychological outcomes. Women in the intervention group had lower actual than anticipated levels of fear and anxiety between baseline and 2 weeks post natal (anxiety: OR -0.72, 95% CI -1.16 to -0.28, P = 0.001); fear (OR -0.62, 95% CI -1.08 to -0.16, P = 0.009). Postnatal response rates were 67% overall at 2 weeks. The additional cost in the intervention arm per woman was £4.83 (CI -£257.93 to £267.59). <br />CONCLUSIONS: <br />Allocation to two-third-trimester group self-hypnosis training sessions did not significantly reduce intra-partum epidural analgesia use or a range of other clinical and psychological variables. The impact of women's anxiety and fear about childbirth needs further investigation.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6f275c5e2e1ec74adc90fd09975cbac6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37940367,"asset_id":13084418,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37940367/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="13084418"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="13084418"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13084418; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13084418]").text(description); $(".js-view-count[data-work-id=13084418]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13084418; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='13084418']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6f275c5e2e1ec74adc90fd09975cbac6" } } $('.js-work-strip[data-work-id=13084418]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":13084418,"title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness","translated_title":"","metadata":{"abstract":"Abstract\r\nOBJECTIVE:\r\n(Primary) To establish the effect of antenatal group self-hypnosis for nulliparous women on intra-partum epidural use.\r\nDESIGN:\r\nMulti-method randomised control trial (RCT).\r\nSETTING:\r\nThree NHS Trusts.\r\nPOPULATION:\r\nNulliparous women not planning elective caesarean, without medication for hypertension and without psychological illness.\r\nMETHODS:\r\nRandomisation at 28-32 weeks' gestation to usual care, or to usual care plus brief self-hypnosis training (two × 90-minute groups at around 32 and 35 weeks' gestation; daily audio self-hypnosis CD). Follow up at 2 and 6 weeks postnatal.\r\nMAIN OUTCOME MEASURES:\r\nPrimary: epidural analgesia. Secondary: associated clinical and psychological outcomes; cost analysis.\r\nRESULTS:\r\nSix hundred and eighty women were randomised. There was no statistically significant difference in epidural use: 27.9% (intervention), 30.3% (control), odds ratio (OR) 0.89 [95% confidence interval (CI): 0.64-1.24], or in 27 of 29 pre-specified secondary clinical and psychological outcomes. Women in the intervention group had lower actual than anticipated levels of fear and anxiety between baseline and 2 weeks post natal (anxiety: OR -0.72, 95% CI -1.16 to -0.28, P = 0.001); fear (OR -0.62, 95% CI -1.08 to -0.16, P = 0.009). Postnatal response rates were 67% overall at 2 weeks. The additional cost in the intervention arm per woman was £4.83 (CI -£257.93 to £267.59).\r\nCONCLUSIONS:\r\nAllocation to two-third-trimester group self-hypnosis training sessions did not significantly reduce intra-partum epidural analgesia use or a range of other clinical and psychological variables. The impact of women's anxiety and fear about childbirth needs further investigation.\r\n"},"translated_abstract":"Abstract\r\nOBJECTIVE:\r\n(Primary) To establish the effect of antenatal group self-hypnosis for nulliparous women on intra-partum epidural use.\r\nDESIGN:\r\nMulti-method randomised control trial (RCT).\r\nSETTING:\r\nThree NHS Trusts.\r\nPOPULATION:\r\nNulliparous women not planning elective caesarean, without medication for hypertension and without psychological illness.\r\nMETHODS:\r\nRandomisation at 28-32 weeks' gestation to usual care, or to usual care plus brief self-hypnosis training (two × 90-minute groups at around 32 and 35 weeks' gestation; daily audio self-hypnosis CD). Follow up at 2 and 6 weeks postnatal.\r\nMAIN OUTCOME MEASURES:\r\nPrimary: epidural analgesia. Secondary: associated clinical and psychological outcomes; cost analysis.\r\nRESULTS:\r\nSix hundred and eighty women were randomised. There was no statistically significant difference in epidural use: 27.9% (intervention), 30.3% (control), odds ratio (OR) 0.89 [95% confidence interval (CI): 0.64-1.24], or in 27 of 29 pre-specified secondary clinical and psychological outcomes. Women in the intervention group had lower actual than anticipated levels of fear and anxiety between baseline and 2 weeks post natal (anxiety: OR -0.72, 95% CI -1.16 to -0.28, P = 0.001); fear (OR -0.62, 95% CI -1.08 to -0.16, P = 0.009). Postnatal response rates were 67% overall at 2 weeks. The additional cost in the intervention arm per woman was £4.83 (CI -£257.93 to £267.59).\r\nCONCLUSIONS:\r\nAllocation to two-third-trimester group self-hypnosis training sessions did not significantly reduce intra-partum epidural analgesia use or a range of other clinical and psychological variables. The impact of women's anxiety and fear about childbirth needs further investigation.\r\n","internal_url":"https://www.academia.edu/13084418/Self_hypnosis_for_intrapartum_pain_management_in_pregnant_nulliparous_women_a_randomised_controlled_trial_of_clinical_effectiveness","translated_internal_url":"","created_at":"2015-06-18T13:16:34.490-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3957782,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":7126,"co_author_invite_id":null,"email":"s***e@uclan.ac.uk","affiliation":"University of Central Lancashire","display_order":-1,"name":"Soo Downe","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957783,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":44705351,"co_author_invite_id":942648,"email":"k***1@uclan.ac.uk","display_order":1,"name":"K. Finlayson","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957784,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":72278626,"co_author_invite_id":942649,"email":"c***n@elht.nhs.uk","display_order":2,"name":"C. Melvin","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957785,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":33441025,"co_author_invite_id":942650,"email":"h***y@nottingham.ac.uk","display_order":3,"name":"H. Spiby","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957786,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942643,"email":"s***0@york.ac.uk","display_order":4,"name":"S. Ali","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957787,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":42538904,"co_author_invite_id":350508,"email":"p***e@lancaster.ac.uk","display_order":5,"name":"Peter Diggle","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957788,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":60821468,"co_author_invite_id":942651,"email":"g***e@gmail.com","display_order":6,"name":"G. Gyte","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957789,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":49163259,"co_author_invite_id":942652,"email":"s***r@hotmail.co.uk","display_order":7,"name":"S. Hinder","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957790,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942653,"email":"v***r@uhsm.nhs.uk","display_order":8,"name":"V. Miller","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957791,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942654,"email":"p***e@liverpool.ac.uk","display_order":9,"name":"P. Slade","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957792,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":134981544,"co_author_invite_id":942655,"email":"a***s@liverpool.ac.uk","display_order":10,"name":"A. Weeks","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957793,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":630300,"email":"p***l@uhsm.nhs.uk","display_order":11,"name":"P. Whorwell","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957794,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":329261,"email":"m***n@elht.nhs.uk","display_order":12,"name":"M. Williamson","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"}],"downloadable_attachments":[{"id":37940367,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940367/thumbnails/1.jpg","file_name":"Downe_et_al-2015-BJOG-_An_International_Journal_of_Obstetrics___Gynaecology_2.pdf","download_url":"https://www.academia.edu/attachments/37940367/download_file","bulk_download_file_name":"Self_hypnosis_for_intrapartum_pain_manag.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940367/Downe_et_al-2015-BJOG-_An_International_Journal_of_Obstetrics___Gynaecology_2-libre.pdf?1434658886=\u0026response-content-disposition=attachment%3B+filename%3DSelf_hypnosis_for_intrapartum_pain_manag.pdf\u0026Expires=1738613826\u0026Signature=UpRzO2uY3kLI4qKQofZbpc1ZtbMDQDt~2RwIk-IHJv2I9U~y3rBfv15KF0VpyBDfwhQxuxQKaLoLsbQSVMeSPKxx3AYKQdTjPiJbrvDuvANGGZE7VpX~QWn82F4Rgcf~cWmVj-A1ExclvmfO7n5fXHE0UWLSyejv4T070dpHp~dNoLucILgDn094gW36BhxL39kxX9qIiJ245m-mSNIe3wgJOjE0wx4~kjtg57xH2wynMa27CrrHGIR7ak2NEStTjjAY6VrB4xYRgo7xLYMwGm2g-h82MVaVdhKobh9C-7S0QB8dtyIGpq4jQiMIR8QHuv-mXlmiSc5ZxgQlMevNkQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Self_hypnosis_for_intrapartum_pain_management_in_pregnant_nulliparous_women_a_randomised_controlled_trial_of_clinical_effectiveness","translated_slug":"","page_count":9,"language":"en","content_type":"Work","summary":"Abstract\r\nOBJECTIVE:\r\n(Primary) To establish the effect of antenatal group self-hypnosis for nulliparous women on intra-partum epidural use.\r\nDESIGN:\r\nMulti-method randomised control trial (RCT).\r\nSETTING:\r\nThree NHS Trusts.\r\nPOPULATION:\r\nNulliparous women not planning elective caesarean, without medication for hypertension and without psychological illness.\r\nMETHODS:\r\nRandomisation at 28-32 weeks' gestation to usual care, or to usual care plus brief self-hypnosis training (two × 90-minute groups at around 32 and 35 weeks' gestation; daily audio self-hypnosis CD). Follow up at 2 and 6 weeks postnatal.\r\nMAIN OUTCOME MEASURES:\r\nPrimary: epidural analgesia. Secondary: associated clinical and psychological outcomes; cost analysis.\r\nRESULTS:\r\nSix hundred and eighty women were randomised. There was no statistically significant difference in epidural use: 27.9% (intervention), 30.3% (control), odds ratio (OR) 0.89 [95% confidence interval (CI): 0.64-1.24], or in 27 of 29 pre-specified secondary clinical and psychological outcomes. Women in the intervention group had lower actual than anticipated levels of fear and anxiety between baseline and 2 weeks post natal (anxiety: OR -0.72, 95% CI -1.16 to -0.28, P = 0.001); fear (OR -0.62, 95% CI -1.08 to -0.16, P = 0.009). Postnatal response rates were 67% overall at 2 weeks. The additional cost in the intervention arm per woman was £4.83 (CI -£257.93 to £267.59).\r\nCONCLUSIONS:\r\nAllocation to two-third-trimester group self-hypnosis training sessions did not significantly reduce intra-partum epidural analgesia use or a range of other clinical and psychological variables. The impact of women's anxiety and fear about childbirth needs further investigation.\r\n","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":37940367,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940367/thumbnails/1.jpg","file_name":"Downe_et_al-2015-BJOG-_An_International_Journal_of_Obstetrics___Gynaecology_2.pdf","download_url":"https://www.academia.edu/attachments/37940367/download_file","bulk_download_file_name":"Self_hypnosis_for_intrapartum_pain_manag.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940367/Downe_et_al-2015-BJOG-_An_International_Journal_of_Obstetrics___Gynaecology_2-libre.pdf?1434658886=\u0026response-content-disposition=attachment%3B+filename%3DSelf_hypnosis_for_intrapartum_pain_manag.pdf\u0026Expires=1738613826\u0026Signature=UpRzO2uY3kLI4qKQofZbpc1ZtbMDQDt~2RwIk-IHJv2I9U~y3rBfv15KF0VpyBDfwhQxuxQKaLoLsbQSVMeSPKxx3AYKQdTjPiJbrvDuvANGGZE7VpX~QWn82F4Rgcf~cWmVj-A1ExclvmfO7n5fXHE0UWLSyejv4T070dpHp~dNoLucILgDn094gW36BhxL39kxX9qIiJ245m-mSNIe3wgJOjE0wx4~kjtg57xH2wynMa27CrrHGIR7ak2NEStTjjAY6VrB4xYRgo7xLYMwGm2g-h82MVaVdhKobh9C-7S0QB8dtyIGpq4jQiMIR8QHuv-mXlmiSc5ZxgQlMevNkQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":4387,"name":"Clinical Trials","url":"https://www.academia.edu/Documents/in/Clinical_Trials"},{"id":9747,"name":"Hypnosis (Psychology)","url":"https://www.academia.edu/Documents/in/Hypnosis_Psychology_"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":40165,"name":"Pain Management","url":"https://www.academia.edu/Documents/in/Pain_Management"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy"},{"id":103289,"name":"Gynecology and Obstetrics","url":"https://www.academia.edu/Documents/in/Gynecology_and_Obstetrics"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="13084299"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/13084299/An_Economic_Analysis_of_Home_Care_Services"><img alt="Research paper thumbnail of An Economic Analysis of Home Care Services" class="work-thumbnail" src="https://attachments.academia-assets.com/38962170/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/13084299/An_Economic_Analysis_of_Home_Care_Services">An Economic Analysis of Home Care Services</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The Health Service Executive will consider how best to configure resources currently invested in ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The Health Service Executive will consider how best to configure resources currently invested in home care packages and respite care so as to facilitate people with dementia to continue living in their own homes and communities for as long as possible and to improve the supports available for carers.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8bb5e7c7d1024e5b225e6a2b5a68ebc9" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38962170,"asset_id":13084299,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38962170/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="13084299"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="13084299"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13084299; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="12695251"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/12695251/CASPER_plus_CollAborative_care_in_Screen_Positive_EldeRs_with_major_depressive_disorder_study_protocol_for_a_randomised_controlled_trial"><img alt="Research paper thumbnail of CASPER plus (CollAborative care in Screen-Positive EldeRs with major depressive disorder): study protocol for a randomised controlled trial" class="work-thumbnail" src="https://attachments.academia-assets.com/37801831/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/12695251/CASPER_plus_CollAborative_care_in_Screen_Positive_EldeRs_with_major_depressive_disorder_study_protocol_for_a_randomised_controlled_trial">CASPER plus (CollAborative care in Screen-Positive EldeRs with major depressive disorder): study protocol for a randomised controlled trial</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/KarenOverend">Karen Overend</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/shaistameer">shaista meer</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/JohnHolmes">John Holmes</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HelenLewis11">Helen Lewis</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/RebeccaWoodhouse">Rebecca Woodhouse</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/McMillanDean">Dean McMillan</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/CarolynChewgraham">Carolyn Chew-graham</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/BaileyDella">Della Bailey</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/KBosanquet">Kate Bosanquet</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/GemmaTraviss">Gemma Traviss</a></span></div><div class="wp-workCard_item"><span>Trials</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Depression accounts for the greatest disease burden of all mental health disorders, c...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Depression accounts for the greatest disease burden of all mental health disorders, contributes heavily to healthcare costs, and by 2020 is set to become the second largest cause of global disability. Although 10% to 16% of people aged 65 years and over are likely to experience depressive symptoms, the condition is under-diagnosed and often inadequately treated in primary care. Later-life depression is associated with chronic illness and disability, cognitive impairment and social isolation. With a progressively ageing population it becomes increasingly important to refine strategies to identity and manage depression in older people. Currently, management may be limited to the prescription of antidepressants where there may be poor concordance; older people may lack awareness of psychosocial interventions and general practitioners may neglect to offer this treatment option. Methods/design: CASPER Plus is a multi-centre, randomised controlled trial of a collaborative care intervention for individuals aged 65 years and over experiencing moderate to severe depression. Selected practices in the North of England identify potentially eligible patients and invite them to participate in the study. A diagnostic interview is carried out and participants with major depressive disorder are randomised to either collaborative care or usual care. The recruitment target is 450 participants. The intervention, behavioural activation and medication management in a collaborative care framework, has been adapted to meet the complex needs of older people. It is delivered over eight to 10 weekly sessions by a case manager liaising with general practitioners. The trial aims to evaluate the clinical and cost effectiveness of collaborative care in addition to usual GP care versus usual GP care alone. The primary clinical outcome, depression severity, will be measured with the Patient Health Questionnaire-9 (PHQ-9) at baseline, 4, 12 and 18 months. Cost effectiveness analysis will assess health-related quality of life using the SF-12 and EQ-5D and will examine cost-consequences of collaborative care. A qualitative process evaluation will be undertaken to explore acceptability, gauge the extent to which the intervention is implemented and to explore sustainability beyond the clinical trial. Discussion: Results will add to existing evidence and a positive outcome may lead to the commissioning of this model of service in primary care.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5623bbbb7066da5941a1dcc47303022f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37801831,"asset_id":12695251,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37801831/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="12695251"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="12695251"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12695251; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="12963906"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/12963906/Screening_for_psychological_and_mental_health_difficulties_in_young_people_who_offend_a_systematic_review_and_decision_model"><img alt="Research paper thumbnail of Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/12963906/Screening_for_psychological_and_mental_health_difficulties_in_young_people_who_offend_a_systematic_review_and_decision_model">Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ShehzadAli13">Shehzad Ali</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SimonGilbody">Simon Gilbody</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://yorku.academia.edu/AmandaPerry">Amanda Perry</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ManeaL">Laura Manea</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/Glanville">Julie Glanville</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a></span></div><div class="wp-workCard_item"><span>Health Technology Assessment</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">There is policy interest in the screening and treatment of mental health problems in young people...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">There is policy interest in the screening and treatment of mental health problems in young people who offend, but the value of such screening is not yet known. To assess the diagnostic test accuracy of screening measures for mental health problems in young people who offend; to evaluate the clinical effectiveness and cost-effectiveness of screening and treatment; to model estimates of cost; to assess the evidence base for screening against UK National Screening Committee criteria; and to identify future research priorities. In total, 25 electronic databases including MEDLINE, PsycINFO, EMBASE and The Cochrane Library were searched from inception until April 2011. Reverse citation searches of included studies were undertaken and reference list of included studies were examined. Two reviewers independently examined titles and abstracts and extracted data from included studies using a standardised form. The inclusion criteria for the review were (1) population - young offenders (aged 10-21 years); (2) intervention/instrument - screening instruments for mental health problems, implementation of a screening programme or a psychological or pharmacological intervention as part of a clinical trial; (3) comparator - for diagnostic test accuracy studies, any standardised diagnostic interview; for trials, any comparator; (4) outcomes - details of diagnostic test accuracy, mental health outcomes over the short or longer term or measurement of cost data; and (5) study design - for diagnostic test accuracy studies, any design; for screening programmes, randomised controlled trials or controlled trials; for clinical effectiveness studies, randomised controlled trials; for economic studies, economic evaluations of screening strategies or interventions. Of 13,580 studies identified, nine, including eight independent samples, met the inclusion criteria for the diagnostic test accuracy and validity of screening measures review. Screening accuracy was typically modest. No studies examined the clinical effectiveness of screening, although 10 studies were identified that examined the clinical effectiveness of interventions for mental health problems. There were too few studies to make firm conclusions about the clinical effectiveness of treatments in this population. No studies met the inclusion criteria for the assessment of the cost-effectiveness of screening or treatment. An exemplar decision model was developed for depression, which identified a number of the likely key drivers of uncertainty, including the prevalence of unidentified mental health problems, the severity of mental health problems and their relationship to generic measures of outcome and the impact of treatment on recidivism. The information evaluated as part of the review was relevant to five of the UK National Screening Committee criteria. On the basis of the above results, none of the five criteria was met. The conclusions of the review are based on limited evidence. Conclusions are tentative and the decision model should be treated as an exemplar. Evidence on the clinical effectiveness and cost-effectiveness of screening for mental health problems in young people who offend is currently lacking. Future research should consider feasibility trials of clinical interventions to establish important parameters ahead of conducting definitive trials. Future diagnostic studies should compare the diagnostic test accuracy of a range of screening instruments, including those recommended for use in the UK in this population. These studies should be designed to reduce the decision uncertainty identified by the exemplar decision model. This study is registered as PROSPERO CRD42011001466. The National Institute for Health Research Health Technology Assessment programme.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="12963906"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="12963906"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12963906; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12963906]").text(description); $(".js-view-count[data-work-id=12963906]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12963906; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='12963906']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=12963906]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":12963906,"title":"Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model","internal_url":"https://www.academia.edu/12963906/Screening_for_psychological_and_mental_health_difficulties_in_young_people_who_offend_a_systematic_review_and_decision_model","owner_id":32158302,"coauthors_can_edit":true,"owner":{"id":32158302,"first_name":"Julie","middle_initials":null,"last_name":"Glanville","page_name":"Glanville","domain_name":"independent","created_at":"2015-06-13T09:22:31.375-07:00","display_name":"Julie Glanville","url":"https://independent.academia.edu/Glanville"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="10242630"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/10242630/Informal_Cost_of_Dementia_Care_A_Proxy_Good_Valuation_in_Ireland"><img alt="Research paper thumbnail of Informal Cost of Dementia Care – A Proxy-Good Valuation in Ireland" class="work-thumbnail" src="https://attachments.academia-assets.com/36334121/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/10242630/Informal_Cost_of_Dementia_Care_A_Proxy_Good_Valuation_in_Ireland">Informal Cost of Dementia Care – A Proxy-Good Valuation in Ireland</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This paper values the informal costs of dementia care in Ireland based on recently agreed nationa...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This paper values the informal costs of dementia care in Ireland based on recently agreed national costing framework. Drawing on a survey of 270 Irish dementia caregivers, the hours of informal care per day are estimated using variables of individual characteristics, functional limitations and behavioural problems. This estimation finds that an interlinked workcohabitation effect significantly predicts the total informal care available and suggests that increasing burden on carers may alter overall welfare. Given conflict in carers' personal priorities, this paper calculates the market value of formal services to inform equitable distribution of dementia care required. By associating "proxy-good' market values to dementia symptoms requiring specific types of care, the per diem costs of care are estimated to range from €240.96 (early-stage) to €570.04 (late-stage). As burnout is a major risk factor in prolonged care, this paper indicates the formal value of the output of care from a public health service perspective. Policy initiatives to improve technical and allocative efficiency of formal dementia services are required to reduce reliance on informal care.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7a282267484a620b7386c4bc2e48c1f8" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":36334121,"asset_id":10242630,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/36334121/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="10242630"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="10242630"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 10242630; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=10242630]").text(description); $(".js-view-count[data-work-id=10242630]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 10242630; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='10242630']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7a282267484a620b7386c4bc2e48c1f8" } } $('.js-work-strip[data-work-id=10242630]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":10242630,"title":"Informal Cost of Dementia Care – A Proxy-Good Valuation in Ireland","translated_title":"","metadata":{"grobid_abstract":"This paper values the informal costs of dementia care in Ireland based on recently agreed national costing framework. 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Policy initiatives to improve technical and allocative efficiency of formal dementia services are required to reduce reliance on informal care.","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"grobid_abstract_attachment_id":36334121},"translated_abstract":null,"internal_url":"https://www.academia.edu/10242630/Informal_Cost_of_Dementia_Care_A_Proxy_Good_Valuation_in_Ireland","translated_internal_url":"","created_at":"2015-01-20T03:46:30.488-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":36334121,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/36334121/thumbnails/1.jpg","file_name":"05_Trepel_article_ESRI_Vol_42-42.pdf","download_url":"https://www.academia.edu/attachments/36334121/download_file","bulk_download_file_name":"Informal_Cost_of_Dementia_Care_A_Proxy_G.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/36334121/05_Trepel_article_ESRI_Vol_42-42-libre.pdf?1421756533=\u0026response-content-disposition=attachment%3B+filename%3DInformal_Cost_of_Dementia_Care_A_Proxy_G.pdf\u0026Expires=1738613827\u0026Signature=dzjbeAWGDbzRqLucbC5PoP4rnO-v79Sj5VBzDoprTuy-KQrM7CXoNkjsRKUvKkh2OXj37EMDipUsZJD-1qQ02kZg95Aftmmy9aLwfP2573P9U0CrA7BgbLKlyF9de7kl-EKa6~28zbDvkxFQyeNwoHBXvIZ9uTeYzRFLCap7Vu~aAc8bGFERmkekAThBZbuyWN47wlKDziTV7fBaq84HYO~aFTca1pRWMzRbz0by6UV1~iIgSF~58zzJeYvAELgCa57SU~WqJzSufJd12MkXp6ho2tjF3JZTU~NdaP4ksS6pYdfMcEHTDNC95NsFNrWgrIPTdYpYQvVYz~vjT7o1uw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Informal_Cost_of_Dementia_Care_A_Proxy_Good_Valuation_in_Ireland","translated_slug":"","page_count":25,"language":"en","content_type":"Work","summary":"This paper values the informal costs of dementia care in Ireland based on recently agreed national costing framework. Drawing on a survey of 270 Irish dementia caregivers, the hours of informal care per day are estimated using variables of individual characteristics, functional limitations and behavioural problems. This estimation finds that an interlinked workcohabitation effect significantly predicts the total informal care available and suggests that increasing burden on carers may alter overall welfare. Given conflict in carers' personal priorities, this paper calculates the market value of formal services to inform equitable distribution of dementia care required. By associating \"proxy-good' market values to dementia symptoms requiring specific types of care, the per diem costs of care are estimated to range from €240.96 (early-stage) to €570.04 (late-stage). As burnout is a major risk factor in prolonged care, this paper indicates the formal value of the output of care from a public health service perspective. Policy initiatives to improve technical and allocative efficiency of formal dementia services are required to reduce reliance on informal care.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":36334121,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/36334121/thumbnails/1.jpg","file_name":"05_Trepel_article_ESRI_Vol_42-42.pdf","download_url":"https://www.academia.edu/attachments/36334121/download_file","bulk_download_file_name":"Informal_Cost_of_Dementia_Care_A_Proxy_G.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/36334121/05_Trepel_article_ESRI_Vol_42-42-libre.pdf?1421756533=\u0026response-content-disposition=attachment%3B+filename%3DInformal_Cost_of_Dementia_Care_A_Proxy_G.pdf\u0026Expires=1738613827\u0026Signature=dzjbeAWGDbzRqLucbC5PoP4rnO-v79Sj5VBzDoprTuy-KQrM7CXoNkjsRKUvKkh2OXj37EMDipUsZJD-1qQ02kZg95Aftmmy9aLwfP2573P9U0CrA7BgbLKlyF9de7kl-EKa6~28zbDvkxFQyeNwoHBXvIZ9uTeYzRFLCap7Vu~aAc8bGFERmkekAThBZbuyWN47wlKDziTV7fBaq84HYO~aFTca1pRWMzRbz0by6UV1~iIgSF~58zzJeYvAELgCa57SU~WqJzSufJd12MkXp6ho2tjF3JZTU~NdaP4ksS6pYdfMcEHTDNC95NsFNrWgrIPTdYpYQvVYz~vjT7o1uw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health"},{"id":3662,"name":"Dementia","url":"https://www.academia.edu/Documents/in/Dementia"},{"id":3776,"name":"Alzheimer's Disease","url":"https://www.academia.edu/Documents/in/Alzheimers_Disease"},{"id":14166,"name":"Informal Caregivers/Carers","url":"https://www.academia.edu/Documents/in/Informal_Caregivers_Carers"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"}],"urls":[{"id":4205657,"url":"http://www.esr.ie/vol42_4/05%20Trepel%20article_ESRI%20Vol%2042-42.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="2438298" id="papers"><div class="js-work-strip profile--work_container" data-work-id="27333919"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/27333919/An_examination_of_the_nutritional_intake_and_anthropometric_status_of_individuals_with_intellectual_disabilities_Results_from_the_SOPHIE_study"><img alt="Research paper thumbnail of An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study" class="work-thumbnail" src="https://attachments.academia-assets.com/47589878/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/27333919/An_examination_of_the_nutritional_intake_and_anthropometric_status_of_individuals_with_intellectual_disabilities_Results_from_the_SOPHIE_study">An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://dcu.academia.edu/Deirdrecorby">Deirdre Corby</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PeterGriffin39">Peter Griffin</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The prevalence of obesity appears greater in people with intellectual disabilities than those in ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The prevalence of obesity appears greater in people with intellectual disabilities than those in the general population. This study aimed to examine the nutritional intake and anthropometric status of individuals with intellectual disabilities. Participants aged 16–64 years were recruited from intellectual disability service provider organizations (n ¼ 131). Data were collected using questionnaires ; 4-day food dairies and weight, height and waist circumference measurements. Parti-cipants' mean body mass index (BMI) was 29.4 kg/m 2 + 6.1, 2.4% were underweight, 22.6% were normal weight, 28.2% were overweight and 46.8% were obese. Having a diagnosis of Down syndrome (p ¼ 0.03) was associated with increasing BMI. Increasing waist circumference was associated</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="243aafe4aa79491df732035f3e79cd41" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":47589878,"asset_id":27333919,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/47589878/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="27333919"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="27333919"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 27333919; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=27333919]").text(description); $(".js-view-count[data-work-id=27333919]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 27333919; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='27333919']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "243aafe4aa79491df732035f3e79cd41" } } $('.js-work-strip[data-work-id=27333919]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":27333919,"title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study","translated_title":"","metadata":{"abstract":"The prevalence of obesity appears greater in people with intellectual disabilities than those in the general population. This study aimed to examine the nutritional intake and anthropometric status of individuals with intellectual disabilities. Participants aged 16–64 years were recruited from intellectual disability service provider organizations (n ¼ 131). Data were collected using questionnaires ; 4-day food dairies and weight, height and waist circumference measurements. Parti-cipants' mean body mass index (BMI) was 29.4 kg/m 2 + 6.1, 2.4% were underweight, 22.6% were normal weight, 28.2% were overweight and 46.8% were obese. Having a diagnosis of Down syndrome (p ¼ 0.03) was associated with increasing BMI. Increasing waist circumference was associated"},"translated_abstract":"The prevalence of obesity appears greater in people with intellectual disabilities than those in the general population. This study aimed to examine the nutritional intake and anthropometric status of individuals with intellectual disabilities. Participants aged 16–64 years were recruited from intellectual disability service provider organizations (n ¼ 131). Data were collected using questionnaires ; 4-day food dairies and weight, height and waist circumference measurements. Parti-cipants' mean body mass index (BMI) was 29.4 kg/m 2 + 6.1, 2.4% were underweight, 22.6% were normal weight, 28.2% were overweight and 46.8% were obese. Having a diagnosis of Down syndrome (p ¼ 0.03) was associated with increasing BMI. Increasing waist circumference was associated","internal_url":"https://www.academia.edu/27333919/An_examination_of_the_nutritional_intake_and_anthropometric_status_of_individuals_with_intellectual_disabilities_Results_from_the_SOPHIE_study","translated_internal_url":"","created_at":"2016-07-28T04:41:12.097-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":22842904,"work_id":27333919,"tagging_user_id":24191374,"tagged_user_id":42072597,"co_author_invite_id":null,"email":"e***4@mail.dcu.ie","display_order":1,"name":"Edel Hoey","title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study"},{"id":22842905,"work_id":27333919,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":5096686,"email":"a***s@gmail.com","display_order":2,"name":"Anthony Staines","title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study"},{"id":22842906,"work_id":27333919,"tagging_user_id":24191374,"tagged_user_id":38267021,"co_author_invite_id":null,"email":"d***y@dcu.ie","affiliation":"Dublin City University","display_order":3,"name":"Deirdre Corby","title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study"},{"id":22842907,"work_id":27333919,"tagging_user_id":24191374,"tagged_user_id":34858983,"co_author_invite_id":null,"email":"s***n@dcu.ie","display_order":4,"name":"Sarah Meegan","title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study"},{"id":22842908,"work_id":27333919,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":3118114,"email":"t***h@dcu.ie","display_order":5,"name":"Treasa McVeigh","title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study"},{"id":22842909,"work_id":27333919,"tagging_user_id":24191374,"tagged_user_id":41959921,"co_author_invite_id":null,"email":"p***n@qub.ac.uk","display_order":6,"name":"Peter Griffin","title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study"},{"id":22842910,"work_id":27333919,"tagging_user_id":24191374,"tagged_user_id":24191374,"co_author_invite_id":5096687,"email":"d***l@leeds.ac.uk","affiliation":"University of Leeds","display_order":7,"name":"Dominic Trépel","title":"An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study"}],"downloadable_attachments":[{"id":47589878,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/47589878/thumbnails/1.jpg","file_name":"Journal_of_Intellectual_Disabilities-2016-Hoey-1744629516657946.pdf","download_url":"https://www.academia.edu/attachments/47589878/download_file","bulk_download_file_name":"An_examination_of_the_nutritional_intake.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/47589878/Journal_of_Intellectual_Disabilities-2016-Hoey-1744629516657946-libre.pdf?1469706413=\u0026response-content-disposition=attachment%3B+filename%3DAn_examination_of_the_nutritional_intake.pdf\u0026Expires=1738613825\u0026Signature=TQLbGM8DyiiyeJpusZtMnUZQnjwMwwlEpcNn~xCUTMBvpmcQK1U0QQHOQ069kmEAmvN2NhV-z5j72cvmSs9TT97VGMR69RxGP~~rcYksTu10nQCDdWe0HTiD1RPdgHICvvyz4NDUwdsKdYbp9HUr-n1Xj4ye~X~8LuCd5Pi1iBYQoPZUQjPwHQUWIUVSk5WshBx-T1Ylaf~f-H6e51b9-COL7Oby0Yy1eCDtZKMgEwSmBVETxFndLWXlFxqxshgvYJKEUyFvxIInVjiCNAUq05G9xTceXTdyGLYUVuJTBNDyKeOe71DBSwlItXWuqjo2unTKuOw0AXcJIT7cbUmpXg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"An_examination_of_the_nutritional_intake_and_anthropometric_status_of_individuals_with_intellectual_disabilities_Results_from_the_SOPHIE_study","translated_slug":"","page_count":20,"language":"en","content_type":"Work","summary":"The prevalence of obesity appears greater in people with intellectual disabilities than those in the general population. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="25636607"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/25636607/HEALTH_TECHNOLOGY_ASSESSMENT_PROMISE_first_trimester_progesterone_therapy_in_women_with_a_history_of_unexplained_recurrent_miscarriages_a_randomised_double_blind_placebo_controlled_international_multicentre_trial_and_economic_evaluation"><img alt="Research paper thumbnail of HEALTH TECHNOLOGY ASSESSMENT PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages – a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation" class="work-thumbnail" src="https://attachments.academia-assets.com/45970702/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/25636607/HEALTH_TECHNOLOGY_ASSESSMENT_PROMISE_first_trimester_progesterone_therapy_in_women_with_a_history_of_unexplained_recurrent_miscarriages_a_randomised_double_blind_placebo_controlled_international_multicentre_trial_and_economic_evaluation">HEALTH TECHNOLOGY ASSESSMENT PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages – a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/EwaTruchanowicz">Ewa Truchanowicz</a></span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5bf41acf7f05a21e9bf407785301636d" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":45970702,"asset_id":25636607,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/45970702/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="25636607"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="25636607"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 25636607; 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href="https://www.academia.edu/22892484/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis"><img alt="Research paper thumbnail of Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/22892484/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis">Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://yorku.academia.edu/AmandaPerry">Amanda Perry</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/VivienPrior">Vivien Prior</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/Glanville">Julie Glanville</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a></span></div><div class="wp-workCard_item"><span>Health technology assessment (Winchester, England)</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Services have variable practices for identifying and providing interventions for &#39;severe atta...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Services have variable practices for identifying and providing interventions for &#39;severe attachment problems&#39; (disorganised attachment patterns and attachment disorders). Several government reports have highlighted the need for better parenting interventions in at-risk groups. This report was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems (the main review). One supplementary review explored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform health economic aspects of the main review. A total of 29 electronic databases were searched with additional mechanisms for identifying a wide pool of references using the Cochrane methodology. Examples of databases searched include PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process & Other Non-Indexed Citations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012)...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="22892484"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="22892484"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22892484; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); 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} }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="20445593"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/20445593/Screening_for_anxiety_disorders_with_the_GAD_7_and_GAD_2_a_systematic_review_and_diagnostic_metaanalysis"><img alt="Research paper thumbnail of Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis" class="work-thumbnail" src="https://attachments.academia-assets.com/41377550/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/20445593/Screening_for_anxiety_disorders_with_the_GAD_7_and_GAD_2_a_systematic_review_and_diagnostic_metaanalysis">Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PlummerFaye">Faye Plummer</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ManeaL">Laura Manea</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identifying anxiety disorders. Methods: A systematic review of the literature was conducted to identify studies that validated the GAD-7 or GAD-2 against a recognized gold standard diagnosis. Pooled estimates of diagnostic test accuracy were produced using random-effects bivariate metaanalysis. Heterogeneity was explored using the I 2 statistic. Results: A total of 12 samples were identified involving 5223 participants; 11 samples provided data on the accuracy of the GAD-7 for identifying generalized anxiety disorder (GAD). Pooled sensitivity and specificity values appeared acceptable at a cutoff point of 8 [sensitivity: 0.83 (95% CI 0.71–0.91), specificity: 0.84 (95% CI 0.70–0.92)] although cutoff scores 7–10 also had similar pooled estimates of sensitivity/specificity. Six samples provided data on the accuracy of the GAD-2 for identifying GAD. Pooled sensitivity and specificity values appeared acceptable at a cutoff of 3 [sensitivity: 0.76 (95% CI 0.55–0.89), specificity: 0.81 (95% CI 0.60–0.92)]. Four studies looked at the accuracy of the questionnaires for identifying any anxiety disorder. Conclusions: The GAD-7 had acceptable properties for identifying GAD at cutoff scores 7–10. The GAD-2 had acceptable properties for identifying GAD at a cutoff score of 3. Further validation studies are needed.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5d3bb0b0a9fe37b32f24078f86456090" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":41377550,"asset_id":20445593,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/41377550/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20445593"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20445593"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20445593; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20445593]").text(description); $(".js-view-count[data-work-id=20445593]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20445593; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20445593']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5d3bb0b0a9fe37b32f24078f86456090" } } $('.js-work-strip[data-work-id=20445593]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20445593,"title":"Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis","translated_title":"","metadata":{"abstract":"Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identifying anxiety disorders. Methods: A systematic review of the literature was conducted to identify studies that validated the GAD-7 or GAD-2 against a recognized gold standard diagnosis. Pooled estimates of diagnostic test accuracy were produced using random-effects bivariate metaanalysis. Heterogeneity was explored using the I 2 statistic. Results: A total of 12 samples were identified involving 5223 participants; 11 samples provided data on the accuracy of the GAD-7 for identifying generalized anxiety disorder (GAD). Pooled sensitivity and specificity values appeared acceptable at a cutoff point of 8 [sensitivity: 0.83 (95% CI 0.71–0.91), specificity: 0.84 (95% CI 0.70–0.92)] although cutoff scores 7–10 also had similar pooled estimates of sensitivity/specificity. Six samples provided data on the accuracy of the GAD-2 for identifying GAD. Pooled sensitivity and specificity values appeared acceptable at a cutoff of 3 [sensitivity: 0.76 (95% CI 0.55–0.89), specificity: 0.81 (95% CI 0.60–0.92)]. Four studies looked at the accuracy of the questionnaires for identifying any anxiety disorder. Conclusions: The GAD-7 had acceptable properties for identifying GAD at cutoff scores 7–10. The GAD-2 had acceptable properties for identifying GAD at a cutoff score of 3. Further validation studies are needed.","ai_title_tag":"GAD-7 and GAD-2 in Anxiety Disorder Diagnosis: A Meta-Analysis"},"translated_abstract":"Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identifying anxiety disorders. Methods: A systematic review of the literature was conducted to identify studies that validated the GAD-7 or GAD-2 against a recognized gold standard diagnosis. Pooled estimates of diagnostic test accuracy were produced using random-effects bivariate metaanalysis. Heterogeneity was explored using the I 2 statistic. Results: A total of 12 samples were identified involving 5223 participants; 11 samples provided data on the accuracy of the GAD-7 for identifying generalized anxiety disorder (GAD). Pooled sensitivity and specificity values appeared acceptable at a cutoff point of 8 [sensitivity: 0.83 (95% CI 0.71–0.91), specificity: 0.84 (95% CI 0.70–0.92)] although cutoff scores 7–10 also had similar pooled estimates of sensitivity/specificity. Six samples provided data on the accuracy of the GAD-2 for identifying GAD. Pooled sensitivity and specificity values appeared acceptable at a cutoff of 3 [sensitivity: 0.76 (95% CI 0.55–0.89), specificity: 0.81 (95% CI 0.60–0.92)]. Four studies looked at the accuracy of the questionnaires for identifying any anxiety disorder. Conclusions: The GAD-7 had acceptable properties for identifying GAD at cutoff scores 7–10. The GAD-2 had acceptable properties for identifying GAD at a cutoff score of 3. Further validation studies are needed.","internal_url":"https://www.academia.edu/20445593/Screening_for_anxiety_disorders_with_the_GAD_7_and_GAD_2_a_systematic_review_and_diagnostic_metaanalysis","translated_internal_url":"","created_at":"2016-01-21T15:22:37.919-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":13302783,"work_id":20445593,"tagging_user_id":24191374,"tagged_user_id":42199162,"co_author_invite_id":3118144,"email":"p***p@leeds.ac.uk","display_order":0,"name":"Faye Plummer","title":"Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis"},{"id":13302784,"work_id":20445593,"tagging_user_id":24191374,"tagged_user_id":32190908,"co_author_invite_id":null,"email":"l***a@york.ac.uk","display_order":4194304,"name":"Laura Manea","title":"Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis"},{"id":13302785,"work_id":20445593,"tagging_user_id":24191374,"tagged_user_id":31763798,"co_author_invite_id":null,"email":"d***n@york.ac.uk","display_order":6291456,"name":"Dean McMillan","title":"Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis"}],"downloadable_attachments":[{"id":41377550,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/41377550/thumbnails/1.jpg","file_name":"1-s2.0-S0163834315002406-main.pdf","download_url":"https://www.academia.edu/attachments/41377550/download_file","bulk_download_file_name":"Screening_for_anxiety_disorders_with_the.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/41377550/1-s2.0-S0163834315002406-main-libre.pdf?1453418671=\u0026response-content-disposition=attachment%3B+filename%3DScreening_for_anxiety_disorders_with_the.pdf\u0026Expires=1738613825\u0026Signature=X1Rp195qdJStskPCT9eoRxAjMbk5LdjWWYwS-94xaugQogakuMfhylm5DacWvC4yRZyUzflJnujGxlSF9PJzSYn7yIbiQpmINHiYoVlxmWuVoIaZJY51fan1oFgxjfIbNCQtzhbY7t1bywm6ey8RljoVzlPcof7Xmn26AiR63IQ3EIgnZHdZta-5AH5Zj6HezoxobemE7v89lIQYO6AFHQNA~9LfxwF39RuGJ~CMar-hMBW2LHyZ-XA2KMzdpa~PyLJrYiD4-PRXAF0On02Jj2AL7zn~gWDYsW-PL1GH9weWuu2GZIE1N7ST0vyeLdQcIoxJ7RGgDCveqO45KjsY0A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Screening_for_anxiety_disorders_with_the_GAD_7_and_GAD_2_a_systematic_review_and_diagnostic_metaanalysis","translated_slug":"","page_count":8,"language":"en","content_type":"Work","summary":"Objective: To systematically review the accuracy of the GAD-7 and GAD-2 questionnaires for identifying anxiety disorders. Methods: A systematic review of the literature was conducted to identify studies that validated the GAD-7 or GAD-2 against a recognized gold standard diagnosis. Pooled estimates of diagnostic test accuracy were produced using random-effects bivariate metaanalysis. Heterogeneity was explored using the I 2 statistic. Results: A total of 12 samples were identified involving 5223 participants; 11 samples provided data on the accuracy of the GAD-7 for identifying generalized anxiety disorder (GAD). Pooled sensitivity and specificity values appeared acceptable at a cutoff point of 8 [sensitivity: 0.83 (95% CI 0.71–0.91), specificity: 0.84 (95% CI 0.70–0.92)] although cutoff scores 7–10 also had similar pooled estimates of sensitivity/specificity. Six samples provided data on the accuracy of the GAD-2 for identifying GAD. Pooled sensitivity and specificity values appeared acceptable at a cutoff of 3 [sensitivity: 0.76 (95% CI 0.55–0.89), specificity: 0.81 (95% CI 0.60–0.92)]. Four studies looked at the accuracy of the questionnaires for identifying any anxiety disorder. Conclusions: The GAD-7 had acceptable properties for identifying GAD at cutoff scores 7–10. The GAD-2 had acceptable properties for identifying GAD at a cutoff score of 3. Further validation studies are needed.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":41377550,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/41377550/thumbnails/1.jpg","file_name":"1-s2.0-S0163834315002406-main.pdf","download_url":"https://www.academia.edu/attachments/41377550/download_file","bulk_download_file_name":"Screening_for_anxiety_disorders_with_the.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/41377550/1-s2.0-S0163834315002406-main-libre.pdf?1453418671=\u0026response-content-disposition=attachment%3B+filename%3DScreening_for_anxiety_disorders_with_the.pdf\u0026Expires=1738613825\u0026Signature=X1Rp195qdJStskPCT9eoRxAjMbk5LdjWWYwS-94xaugQogakuMfhylm5DacWvC4yRZyUzflJnujGxlSF9PJzSYn7yIbiQpmINHiYoVlxmWuVoIaZJY51fan1oFgxjfIbNCQtzhbY7t1bywm6ey8RljoVzlPcof7Xmn26AiR63IQ3EIgnZHdZta-5AH5Zj6HezoxobemE7v89lIQYO6AFHQNA~9LfxwF39RuGJ~CMar-hMBW2LHyZ-XA2KMzdpa~PyLJrYiD4-PRXAF0On02Jj2AL7zn~gWDYsW-PL1GH9weWuu2GZIE1N7ST0vyeLdQcIoxJ7RGgDCveqO45KjsY0A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1314,"name":"Anxiety Disorders","url":"https://www.academia.edu/Documents/in/Anxiety_Disorders"},{"id":6482,"name":"Meta-Analysis and Systematic Review","url":"https://www.academia.edu/Documents/in/Meta-Analysis_and_Systematic_Review"},{"id":43363,"name":"Screening","url":"https://www.academia.edu/Documents/in/Screening"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="20445561"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/20445561/The_feasibility_and_acceptability_of_using_the_Mother_Generated_Index_MGI_as_a_Patient_Reported_Outcome_Measure_in_a_randomised_controlled_trial_of_maternity_care_and_SHIP_trial_team"><img alt="Research paper thumbnail of The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team" class="work-thumbnail" src="https://attachments.academia-assets.com/41377522/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/20445561/The_feasibility_and_acceptability_of_using_the_Mother_Generated_Index_MGI_as_a_Patient_Reported_Outcome_Measure_in_a_randomised_controlled_trial_of_maternity_care_and_SHIP_trial_team">The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PeterDiggle">Peter Diggle</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is we...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is well established, but commonly-used PROM item-sets do not necessarily capture what all respondents consider important. Measuring complex constructs is particularly difficult in randomised controlled trials (RCTs). The Mother-Generated Index (MGI) is a validated antenatal and postnatal QoL instrument in which the variables and scores are completely respondent-driven. This paper reports on the feasibility and acceptability of the MGI in an RCT, and compares the resulting variables and QoL scores with more commonly used instruments. Methods: The single-page MGI was included at the end of a ten page questionnaire pack and posted to the RCT participants at baseline (28–32 weeks' gestation) and follow-up (six weeks postnatal). Feasibility and acceptability were assessed by ease of administration, data entry and completion rates. Variables cited by women were analysed thematically. MGI QoL scores were compared with outcomes from the EQ-5D-3 L; Edinburgh Postnatal Depression Scale; Satisfaction With Life Scale; and State Trait Anxiety Inventory.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="098772e5db46604a6ef9385ca35dd840" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":41377522,"asset_id":20445561,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/41377522/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20445561"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20445561"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20445561; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20445561]").text(description); $(".js-view-count[data-work-id=20445561]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20445561; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20445561']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "098772e5db46604a6ef9385ca35dd840" } } $('.js-work-strip[data-work-id=20445561]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20445561,"title":"The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team","translated_title":"","metadata":{"abstract":"Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is well established, but commonly-used PROM item-sets do not necessarily capture what all respondents consider important. Measuring complex constructs is particularly difficult in randomised controlled trials (RCTs). The Mother-Generated Index (MGI) is a validated antenatal and postnatal QoL instrument in which the variables and scores are completely respondent-driven. This paper reports on the feasibility and acceptability of the MGI in an RCT, and compares the resulting variables and QoL scores with more commonly used instruments. Methods: The single-page MGI was included at the end of a ten page questionnaire pack and posted to the RCT participants at baseline (28–32 weeks' gestation) and follow-up (six weeks postnatal). Feasibility and acceptability were assessed by ease of administration, data entry and completion rates. Variables cited by women were analysed thematically. MGI QoL scores were compared with outcomes from the EQ-5D-3 L; Edinburgh Postnatal Depression Scale; Satisfaction With Life Scale; and State Trait Anxiety Inventory.","ai_title_tag":"Feasibility of the Mother-Generated Index in RCTs"},"translated_abstract":"Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is well established, but commonly-used PROM item-sets do not necessarily capture what all respondents consider important. Measuring complex constructs is particularly difficult in randomised controlled trials (RCTs). The Mother-Generated Index (MGI) is a validated antenatal and postnatal QoL instrument in which the variables and scores are completely respondent-driven. This paper reports on the feasibility and acceptability of the MGI in an RCT, and compares the resulting variables and QoL scores with more commonly used instruments. Methods: The single-page MGI was included at the end of a ten page questionnaire pack and posted to the RCT participants at baseline (28–32 weeks' gestation) and follow-up (six weeks postnatal). Feasibility and acceptability were assessed by ease of administration, data entry and completion rates. Variables cited by women were analysed thematically. MGI QoL scores were compared with outcomes from the EQ-5D-3 L; Edinburgh Postnatal Depression Scale; Satisfaction With Life Scale; and State Trait Anxiety Inventory.","internal_url":"https://www.academia.edu/20445561/The_feasibility_and_acceptability_of_using_the_Mother_Generated_Index_MGI_as_a_Patient_Reported_Outcome_Measure_in_a_randomised_controlled_trial_of_maternity_care_and_SHIP_trial_team","translated_internal_url":"","created_at":"2016-01-21T15:19:03.430-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":13302754,"work_id":20445561,"tagging_user_id":24191374,"tagged_user_id":57000,"co_author_invite_id":null,"email":"a***n@dundee.ac.uk","affiliation":"University of Dundee","display_order":0,"name":"Andrew Symon","title":"The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team"},{"id":13302755,"work_id":20445561,"tagging_user_id":24191374,"tagged_user_id":7126,"co_author_invite_id":null,"email":"s***e@uclan.ac.uk","affiliation":"University of Central Lancashire","display_order":4194304,"name":"Soo Downe","title":"The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team"},{"id":13302756,"work_id":20445561,"tagging_user_id":24191374,"tagged_user_id":44705351,"co_author_invite_id":942648,"email":"k***1@uclan.ac.uk","display_order":6291456,"name":"K. Finlayson","title":"The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team"},{"id":13302757,"work_id":20445561,"tagging_user_id":24191374,"tagged_user_id":42538904,"co_author_invite_id":350508,"email":"p***e@lancaster.ac.uk","display_order":7340032,"name":"Peter Diggle","title":"The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team"}],"downloadable_attachments":[{"id":41377522,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/41377522/thumbnails/1.jpg","file_name":"s12874-015-0092-0.pdf","download_url":"https://www.academia.edu/attachments/41377522/download_file","bulk_download_file_name":"The_feasibility_and_acceptability_of_usi.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/41377522/s12874-015-0092-0-libre.pdf?1453418365=\u0026response-content-disposition=attachment%3B+filename%3DThe_feasibility_and_acceptability_of_usi.pdf\u0026Expires=1738613826\u0026Signature=T5uGf8xr5lVrPBUlKz~mJSSC7w-HLv6Mu3xv63VqX83YtqgrYNBl28pJhbpE6RecREJ~HvloftvbDKaG1ff8F3R7CkreoTKOXU8EtgBReXvvG5TCoHbumxGPT-~tRkEqF73SdKmO3g79D8bl0n7jBY~ZQNdq9wni0rdbnddzT~P19JvqfKBdzyqUYSMalHfyc60ZZOFhFCyrOs4Ms9VvjuPlucvQWNlUw0H6lgtg2jA84IQdnD-NNux1u5B3jpFJU3gQH42QS9bzUGjdm4DISFy3An~-G4-lq4vb90~N0k8zC~EZZtztwyy~u2CjRTDHITWFMb5rQQxm3-eRhYAc0g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"The_feasibility_and_acceptability_of_using_the_Mother_Generated_Index_MGI_as_a_Patient_Reported_Outcome_Measure_in_a_randomised_controlled_trial_of_maternity_care_and_SHIP_trial_team","translated_slug":"","page_count":9,"language":"en","content_type":"Work","summary":"Background: Using patient-reported outcome measures (PROMs) to assess Quality of Life (QoL) is well established, but commonly-used PROM item-sets do not necessarily capture what all respondents consider important. Measuring complex constructs is particularly difficult in randomised controlled trials (RCTs). The Mother-Generated Index (MGI) is a validated antenatal and postnatal QoL instrument in which the variables and scores are completely respondent-driven. This paper reports on the feasibility and acceptability of the MGI in an RCT, and compares the resulting variables and QoL scores with more commonly used instruments. Methods: The single-page MGI was included at the end of a ten page questionnaire pack and posted to the RCT participants at baseline (28–32 weeks' gestation) and follow-up (six weeks postnatal). Feasibility and acceptability were assessed by ease of administration, data entry and completion rates. Variables cited by women were analysed thematically. MGI QoL scores were compared with outcomes from the EQ-5D-3 L; Edinburgh Postnatal Depression Scale; Satisfaction With Life Scale; and State Trait Anxiety Inventory.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":41377522,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/41377522/thumbnails/1.jpg","file_name":"s12874-015-0092-0.pdf","download_url":"https://www.academia.edu/attachments/41377522/download_file","bulk_download_file_name":"The_feasibility_and_acceptability_of_usi.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/41377522/s12874-015-0092-0-libre.pdf?1453418365=\u0026response-content-disposition=attachment%3B+filename%3DThe_feasibility_and_acceptability_of_usi.pdf\u0026Expires=1738613826\u0026Signature=T5uGf8xr5lVrPBUlKz~mJSSC7w-HLv6Mu3xv63VqX83YtqgrYNBl28pJhbpE6RecREJ~HvloftvbDKaG1ff8F3R7CkreoTKOXU8EtgBReXvvG5TCoHbumxGPT-~tRkEqF73SdKmO3g79D8bl0n7jBY~ZQNdq9wni0rdbnddzT~P19JvqfKBdzyqUYSMalHfyc60ZZOFhFCyrOs4Ms9VvjuPlucvQWNlUw0H6lgtg2jA84IQdnD-NNux1u5B3jpFJU3gQH42QS9bzUGjdm4DISFy3An~-G4-lq4vb90~N0k8zC~EZZtztwyy~u2CjRTDHITWFMb5rQQxm3-eRhYAc0g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":5409,"name":"Health Outcomes","url":"https://www.academia.edu/Documents/in/Health_Outcomes"},{"id":8910,"name":"Evaluation","url":"https://www.academia.edu/Documents/in/Evaluation"},{"id":103289,"name":"Gynecology and Obstetrics","url":"https://www.academia.edu/Documents/in/Gynecology_and_Obstetrics"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="20445538"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/20445538/People_with_intellectual_disability_and_their_families_perspectives_of_Special_Olympics_Ireland_Qualitative_findings_from_the_SOPHIE_study"><img alt="Research paper thumbnail of People with intellectual disability and their families' perspectives of Special Olympics Ireland: Qualitative findings from the SOPHIE study" class="work-thumbnail" src="https://attachments.academia-assets.com/41377483/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/20445538/People_with_intellectual_disability_and_their_families_perspectives_of_Special_Olympics_Ireland_Qualitative_findings_from_the_SOPHIE_study">People with intellectual disability and their families' perspectives of Special Olympics Ireland: Qualitative findings from the SOPHIE study</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://dcu.academia.edu/Deirdrecorby">Deirdre Corby</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/VeronicaLambert">Veronica Lambert</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/EdelHoey">Edel Hoey</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SarahMeegan">Sarah Meegan</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/PeterGriffin39">Peter Griffin</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Previous research has highlighted that while involvement in Special Olympics can have benefits fo...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Previous research has highlighted that while involvement in Special Olympics can have benefits for athletes and their families, there can also be many barriers to participation. This qualitative study, which was part of a large mixed-method study, examined the experiences and perspectives of people with intellectual disability, their families and staff who work with them, about Special Olympics Ireland (SOI). A total of 47 participants (15 athletes, 6 non-athletes, 18 family members and 8 staff members) participated in focus group and individual interviews. Supplemental data, gathered as part of the larger study extracted from open-ended survey questions completed by 97 family members also informed this element. Findings revealed four main themes: impact of participation on athletes, impact of involvement on families, barriers to participation and how to enhance participation rates. Involvement in Special Olympics impacted positively on the quality of life of athletes and families. Enhanced availability of user-friendly information and service accessibility were important drivers identified for enhancing participation rates in Special Olympics.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="998c51bed9728c8ad40151453acdcbe4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":41377483,"asset_id":20445538,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/41377483/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20445538"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20445538"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20445538; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20445538]").text(description); $(".js-view-count[data-work-id=20445538]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20445538; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20445538']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "998c51bed9728c8ad40151453acdcbe4" } } $('.js-work-strip[data-work-id=20445538]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20445538,"title":"People with intellectual disability and their families' perspectives of Special Olympics Ireland: Qualitative findings from the SOPHIE study","translated_title":"","metadata":{"abstract":"Previous research has highlighted that while involvement in Special Olympics can have benefits for athletes and their families, there can also be many barriers to participation. This qualitative study, which was part of a large mixed-method study, examined the experiences and perspectives of people with intellectual disability, their families and staff who work with them, about Special Olympics Ireland (SOI). A total of 47 participants (15 athletes, 6 non-athletes, 18 family members and 8 staff members) participated in focus group and individual interviews. Supplemental data, gathered as part of the larger study extracted from open-ended survey questions completed by 97 family members also informed this element. Findings revealed four main themes: impact of participation on athletes, impact of involvement on families, barriers to participation and how to enhance participation rates. Involvement in Special Olympics impacted positively on the quality of life of athletes and families. 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Limited evidence mainly using single-case designs suggests that they can reduce anxiety and challenging behaviour.<br />Objectives<br />The objectives were to conduct a systematic review, use this to develop a manualised intervention and run a feasibility trial to inform a fully powered randomised controlled trial (RCT) on their clinical effectiveness and cost-effectiveness in schools.<br />Design<br />This is a three-stage study following the Medical Research Council framework for complex interventions. Specifically, it involved a theoretical phase, a qualitative stage and a feasibility trial stage.<br />Setting<br />Qualitative interviews and focus groups took place in Child and Adolescent Mental Health Service and primary care settings. The feasibility study took place in 37 local mainstream schools.<br />Participants<br />Fifty children (aged 5–15 years) in mainstream school settings with a diagnosis of ASD were entered into the trial. For each child, an associated teacher and parent was also recruited.<br />Interventions<br />The intervention was a goal-setting session followed by a manualised toolkit (including a training session) for creating Social Stories™ for use with school-aged children. The comparator treatment was a goal-setting session followed by an attention control. Both arms received treatment as usual.<br />Main outcome measures<br />Outcomes tested as part of the feasibility study included child- and proxy-completed questionnaires for mental health, quality of life and goal-based outcome measures. Adults additionally completed behaviour diaries and the parental stress index.<br />Results<br />The review found that the research into social stories is predominantly based in the USA, carried out in under-12-year-olds and using single-case designs. Most studies either did not follow established Social Story criteria or did not report if they did. The assessment of effectiveness presents a largely positive picture but is limited by methodological issues. There were no adequate RCTs and insufficient information to assess a number of important sources of potential bias in most studies. A manualised intervention was produced using an iterative process between user focus groups and a writing team, and assessed in the feasibility study. All 50 participant groups were recruited within the study time frame. Two outcome measures, the Social Responsiveness Scale-2 and the custom-made goal-based measure, showed high levels of completion rates and appeared to be capturing social and behaviour skills targeted by the use of Social Stories. Detailed recommendations for a full trial are provided.<br />Limitations<br />Blinding of participants was not feasible. Treatment fidelity was not assessed because of low levels of story return rates.<br />Conclusions<br />The study showed that a fully powered RCT is feasible with an extended geographical footprint. A large amount of data and information has helped to inform the design of this RCT, which will be the subject of a future research grant application. Future work could focus on developing an appropriate blinded outcome measure for this population.<br />Study registration<br />This study is registered as PROSPERO CRD42011001440.<br />Trial registration<br />Current Controlled Trials ISRCTN96286707.<br />Funding<br />This project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 6. See the NIHR Journals Library website for further project information.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4ff1a63e8bf0a54de098a8f74a49e2d5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":41373607,"asset_id":20440571,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/41373607/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20440571"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20440571"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20440571; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20440571]").text(description); $(".js-view-count[data-work-id=20440571]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20440571; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20440571']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4ff1a63e8bf0a54de098a8f74a49e2d5" } } $('.js-work-strip[data-work-id=20440571]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20440571,"title":"Social Stories to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised controlled trial with nested qualitative and cost-effectiveness","translated_title":"","metadata":{"abstract":"Background\nA Social Story™ (Carol Gray) is a child-friendly intervention that is used to give children with autism spectrum disorders (ASDs) social information in situations where they have social difficulties. Limited evidence mainly using single-case designs suggests that they can reduce anxiety and challenging behaviour.\nObjectives\nThe objectives were to conduct a systematic review, use this to develop a manualised intervention and run a feasibility trial to inform a fully powered randomised controlled trial (RCT) on their clinical effectiveness and cost-effectiveness in schools.\nDesign\nThis is a three-stage study following the Medical Research Council framework for complex interventions. Specifically, it involved a theoretical phase, a qualitative stage and a feasibility trial stage.\nSetting\nQualitative interviews and focus groups took place in Child and Adolescent Mental Health Service and primary care settings. The feasibility study took place in 37 local mainstream schools.\nParticipants\nFifty children (aged 5–15 years) in mainstream school settings with a diagnosis of ASD were entered into the trial. For each child, an associated teacher and parent was also recruited.\nInterventions\nThe intervention was a goal-setting session followed by a manualised toolkit (including a training session) for creating Social Stories™ for use with school-aged children. The comparator treatment was a goal-setting session followed by an attention control. Both arms received treatment as usual.\nMain outcome measures\nOutcomes tested as part of the feasibility study included child- and proxy-completed questionnaires for mental health, quality of life and goal-based outcome measures. Adults additionally completed behaviour diaries and the parental stress index.\nResults\nThe review found that the research into social stories is predominantly based in the USA, carried out in under-12-year-olds and using single-case designs. Most studies either did not follow established Social Story criteria or did not report if they did. The assessment of effectiveness presents a largely positive picture but is limited by methodological issues. There were no adequate RCTs and insufficient information to assess a number of important sources of potential bias in most studies. A manualised intervention was produced using an iterative process between user focus groups and a writing team, and assessed in the feasibility study. All 50 participant groups were recruited within the study time frame. Two outcome measures, the Social Responsiveness Scale-2 and the custom-made goal-based measure, showed high levels of completion rates and appeared to be capturing social and behaviour skills targeted by the use of Social Stories. Detailed recommendations for a full trial are provided.\nLimitations\nBlinding of participants was not feasible. Treatment fidelity was not assessed because of low levels of story return rates.\nConclusions\nThe study showed that a fully powered RCT is feasible with an extended geographical footprint. A large amount of data and information has helped to inform the design of this RCT, which will be the subject of a future research grant application. Future work could focus on developing an appropriate blinded outcome measure for this population.\nStudy registration\nThis study is registered as PROSPERO CRD42011001440.\nTrial registration\nCurrent Controlled Trials ISRCTN96286707.\nFunding\nThis project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 6. See the NIHR Journals Library website for further project information."},"translated_abstract":"Background\nA Social Story™ (Carol Gray) is a child-friendly intervention that is used to give children with autism spectrum disorders (ASDs) social information in situations where they have social difficulties. Limited evidence mainly using single-case designs suggests that they can reduce anxiety and challenging behaviour.\nObjectives\nThe objectives were to conduct a systematic review, use this to develop a manualised intervention and run a feasibility trial to inform a fully powered randomised controlled trial (RCT) on their clinical effectiveness and cost-effectiveness in schools.\nDesign\nThis is a three-stage study following the Medical Research Council framework for complex interventions. Specifically, it involved a theoretical phase, a qualitative stage and a feasibility trial stage.\nSetting\nQualitative interviews and focus groups took place in Child and Adolescent Mental Health Service and primary care settings. The feasibility study took place in 37 local mainstream schools.\nParticipants\nFifty children (aged 5–15 years) in mainstream school settings with a diagnosis of ASD were entered into the trial. For each child, an associated teacher and parent was also recruited.\nInterventions\nThe intervention was a goal-setting session followed by a manualised toolkit (including a training session) for creating Social Stories™ for use with school-aged children. The comparator treatment was a goal-setting session followed by an attention control. Both arms received treatment as usual.\nMain outcome measures\nOutcomes tested as part of the feasibility study included child- and proxy-completed questionnaires for mental health, quality of life and goal-based outcome measures. Adults additionally completed behaviour diaries and the parental stress index.\nResults\nThe review found that the research into social stories is predominantly based in the USA, carried out in under-12-year-olds and using single-case designs. Most studies either did not follow established Social Story criteria or did not report if they did. The assessment of effectiveness presents a largely positive picture but is limited by methodological issues. There were no adequate RCTs and insufficient information to assess a number of important sources of potential bias in most studies. A manualised intervention was produced using an iterative process between user focus groups and a writing team, and assessed in the feasibility study. All 50 participant groups were recruited within the study time frame. Two outcome measures, the Social Responsiveness Scale-2 and the custom-made goal-based measure, showed high levels of completion rates and appeared to be capturing social and behaviour skills targeted by the use of Social Stories. Detailed recommendations for a full trial are provided.\nLimitations\nBlinding of participants was not feasible. Treatment fidelity was not assessed because of low levels of story return rates.\nConclusions\nThe study showed that a fully powered RCT is feasible with an extended geographical footprint. A large amount of data and information has helped to inform the design of this RCT, which will be the subject of a future research grant application. Future work could focus on developing an appropriate blinded outcome measure for this population.\nStudy registration\nThis study is registered as PROSPERO CRD42011001440.\nTrial registration\nCurrent Controlled Trials ISRCTN96286707.\nFunding\nThis project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 6. 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Social Story™ (Carol Gray) is a child-friendly intervention that is used to give children with autism spectrum disorders (ASDs) social information in situations where they have social difficulties. Limited evidence mainly using single-case designs suggests that they can reduce anxiety and challenging behaviour.\nObjectives\nThe objectives were to conduct a systematic review, use this to develop a manualised intervention and run a feasibility trial to inform a fully powered randomised controlled trial (RCT) on their clinical effectiveness and cost-effectiveness in schools.\nDesign\nThis is a three-stage study following the Medical Research Council framework for complex interventions. Specifically, it involved a theoretical phase, a qualitative stage and a feasibility trial stage.\nSetting\nQualitative interviews and focus groups took place in Child and Adolescent Mental Health Service and primary care settings. The feasibility study took place in 37 local mainstream schools.\nParticipants\nFifty children (aged 5–15 years) in mainstream school settings with a diagnosis of ASD were entered into the trial. For each child, an associated teacher and parent was also recruited.\nInterventions\nThe intervention was a goal-setting session followed by a manualised toolkit (including a training session) for creating Social Stories™ for use with school-aged children. The comparator treatment was a goal-setting session followed by an attention control. Both arms received treatment as usual.\nMain outcome measures\nOutcomes tested as part of the feasibility study included child- and proxy-completed questionnaires for mental health, quality of life and goal-based outcome measures. Adults additionally completed behaviour diaries and the parental stress index.\nResults\nThe review found that the research into social stories is predominantly based in the USA, carried out in under-12-year-olds and using single-case designs. Most studies either did not follow established Social Story criteria or did not report if they did. The assessment of effectiveness presents a largely positive picture but is limited by methodological issues. There were no adequate RCTs and insufficient information to assess a number of important sources of potential bias in most studies. A manualised intervention was produced using an iterative process between user focus groups and a writing team, and assessed in the feasibility study. All 50 participant groups were recruited within the study time frame. Two outcome measures, the Social Responsiveness Scale-2 and the custom-made goal-based measure, showed high levels of completion rates and appeared to be capturing social and behaviour skills targeted by the use of Social Stories. Detailed recommendations for a full trial are provided.\nLimitations\nBlinding of participants was not feasible. Treatment fidelity was not assessed because of low levels of story return rates.\nConclusions\nThe study showed that a fully powered RCT is feasible with an extended geographical footprint. A large amount of data and information has helped to inform the design of this RCT, which will be the subject of a future research grant application. Future work could focus on developing an appropriate blinded outcome measure for this population.\nStudy registration\nThis study is registered as PROSPERO CRD42011001440.\nTrial registration\nCurrent Controlled Trials ISRCTN96286707.\nFunding\nThis project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 6. See the NIHR Journals Library website for further project information.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":41373607,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/41373607/thumbnails/1.jpg","file_name":"FullReport-hta20060.pdf","download_url":"https://www.academia.edu/attachments/41373607/download_file","bulk_download_file_name":"Social_Stories_to_alleviate_challenging.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/41373607/FullReport-hta20060-libre.pdf?1453400776=\u0026response-content-disposition=attachment%3B+filename%3DSocial_Stories_to_alleviate_challenging.pdf\u0026Expires=1738613826\u0026Signature=NioHoH0xsrbLdErQWPhQZKtnSoDvKUA-gWylU6F3~jW5RN3PuuHDa7LASUhBMiznikb0irGaCcYXO58v2UjPF9g98u0z0pp8XB~Z1Z854y4K5NswCzaJzMZ~kULAyWUuWfap6ntIPof3ObM4J8e-DGZjEXpMT3rlBfhYML9U71cp~iomylqKc~eRix2Mhj3rOYzoz4C5ZWM146LuuG7yWZx2KEx-P0IGtZB7GiymqZ1l0mzfwPDqAhCvXH1LXXkyCMV3Upy-d-kN~fz5AFHjyk7hX8MSxWv7sly0t-H6gDoBVTvMdkdtOlCZf6KpWxdhghsbJLUAvnhFkK6SrCVM0Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":4270,"name":"Autism Spectrum Disorders","url":"https://www.academia.edu/Documents/in/Autism_Spectrum_Disorders"},{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="16363671"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/16363671/An_Economic_Analysis_of_Home_Care_Services_for_People_with_Dementia_Executive_Summary_"><img alt="Research paper thumbnail of An Economic Analysis of Home Care Services for People with Dementia (Executive Summary)" class="work-thumbnail" src="https://attachments.academia-assets.com/38962882/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/16363671/An_Economic_Analysis_of_Home_Care_Services_for_People_with_Dementia_Executive_Summary_">An Economic Analysis of Home Care Services for People with Dementia (Executive Summary)</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/MargaretCrean">Margaret Crean</a></span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="d45ae66ae729f22d78906735f6073bad" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38962882,"asset_id":16363671,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38962882/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="16363671"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="16363671"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 16363671; 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It highlights the importance of providing care in home settings, the role of case management approaches in optimizing care delivery, and recommendations for policy to effectively support individuals with dementia and their caregivers. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="15629050"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/15629050/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial"><img alt="Research paper thumbnail of Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial" class="work-thumbnail" src="https://attachments.academia-assets.com/43017748/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/15629050/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial">Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SimonGilbody">Simon Gilbody</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://durham.academia.edu/BenAldersonDay">Ben Alderson-Day</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/LisaDyson">Lisa Dyson</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ShehzadAli13">Shehzad Ali</a></span></div><div class="wp-workCard_item"><span>BMJ open</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant med...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computer-administered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). Adolescents aged 12-18 with low mood/depression, (scoring ≥20 on the Mood and Feelings Questionnaire (MFQ)), will be approa...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3b8a17199fabc21726b2ebf02898bada" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":43017748,"asset_id":15629050,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/43017748/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15629050"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15629050"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15629050; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15629050]").text(description); $(".js-view-count[data-work-id=15629050]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15629050; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15629050']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "3b8a17199fabc21726b2ebf02898bada" } } $('.js-work-strip[data-work-id=15629050]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15629050,"title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial","translated_title":"","metadata":{"abstract":"The 1 year prevalence of depression in adolescents is about 2%. 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href="https://www.academia.edu/14455901/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis"><img alt="Research paper thumbnail of Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis" class="work-thumbnail" src="https://attachments.academia-assets.com/38313392/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/14455901/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis">Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/VAllgar">Victoria Allgar</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ManeaL">Laura Manea</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/JennyFell">Jenny Fell</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://yorku.academia.edu/AmandaPerry">Amanda Perry</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/VivienPrior">Vivien Prior</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/WhittonClare">Clare Whitton</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background and objectives: Services have variable practices for identifying and providing interve...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background and objectives: Services have variable practices for identifying and providing interventions <br />for ‘severe attachment problems’ (disorganised attachment patterns and attachment disorders). Several <br />government reports have highlighted the need for better parenting interventions in at-risk groups. This <br />report was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting <br />interventions for children with severe attachment problems (the main review). One supplementary review <br />explored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform <br />health economic aspects of the main review. <br />Data sources: A total of 29 electronic databases were searched with additional mechanisms for <br />identifying a wide pool of references using the Cochrane methodology. Examples of databases searched <br />include PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process & Other Non-Indexed <br />Citations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried <br />out between 6 and 12 January 2012. <br />Review methods: Papers identified were screened and data were extracted by two independent <br />reviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were <br />used, including quality assessment of diagnostic accuracy studies – version 2 and the Cochrane risk of bias <br />tool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken. <br />A health economics analysis was conducted. <br />Results: The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting <br />interventions to improve attachment patterns, and one involving children with reactive attachment <br />disorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed <br />statistically significant improvement in disorganised attachment. The interventions saw less disorganised <br />attachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65; <br />p < 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without <br />video feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool <br />demonstrating validity or psychometric data. Only five reported test–retest data. Twenty-six studies <br />reported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach’s alphas were reported <br />in 12 studies for the comparative tests (11 with α > 0.7) and four studies for the reference tests (four with <br />α > 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with <br />another assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment <br />Interview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment <br />disorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference <br />standard, two studies were found with disorganised attachment at baseline, with one finding raised <br />psychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model <br />could not be justifiably populated. This, alongside other findings, informed research priorities. <br />Limitations: There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our <br />health economists for long-term sequelae, yielded a limited number of papers. <br />Conclusions: Maternal sensitivity interventions show good outcomes in at-risk populations, but require <br />further research with complex children. The SSP and RDC for attachment disorders remain the reference <br />standards for identification until more concurrent and predictive validity research is conducted. A birth <br />cohort with sequential attachment measures and outcomes across different domains is recommended with <br />further, methodologically sound randomised controlled intervention trials. The main area identified for <br />future work was a need for good-quality RCTs in at-risk groups such as those entering foster care <br />or adoption. <br />Study registration: This study is registered as PROSPERO CRD42011001395. <br />Funding: The National Institute for Health Research Health Technology Assessment programme. <br />ABSTRACT <br />NIHR Journals Library <a href="http://www.journalslibrary.nihr.ac.uk" rel="nofollow">www.journalslibrary.nihr.ac.uk</a> <br />viii</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ff2afece6df36dad1ff2d47353759f13" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38313392,"asset_id":14455901,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38313392/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="14455901"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="14455901"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 14455901; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=14455901]").text(description); $(".js-view-count[data-work-id=14455901]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 14455901; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='14455901']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ff2afece6df36dad1ff2d47353759f13" } } $('.js-work-strip[data-work-id=14455901]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":14455901,"title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis","translated_title":"","metadata":{"abstract":"Background and objectives: Services have variable practices for identifying and providing interventions\r\nfor ‘severe attachment problems’ (disorganised attachment patterns and attachment disorders). Several\r\ngovernment reports have highlighted the need for better parenting interventions in at-risk groups. This\r\nreport was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting\r\ninterventions for children with severe attachment problems (the main review). One supplementary review\r\nexplored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform\r\nhealth economic aspects of the main review.\r\nData sources: A total of 29 electronic databases were searched with additional mechanisms for\r\nidentifying a wide pool of references using the Cochrane methodology. Examples of databases searched\r\ninclude PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process \u0026 Other Non-Indexed\r\nCitations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried\r\nout between 6 and 12 January 2012.\r\nReview methods: Papers identified were screened and data were extracted by two independent\r\nreviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were\r\nused, including quality assessment of diagnostic accuracy studies – version 2 and the Cochrane risk of bias\r\ntool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken.\r\nA health economics analysis was conducted.\r\nResults: The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting\r\ninterventions to improve attachment patterns, and one involving children with reactive attachment\r\ndisorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed\r\nstatistically significant improvement in disorganised attachment. The interventions saw less disorganised\r\nattachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65;\r\np \u003c 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without\r\nvideo feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool\r\ndemonstrating validity or psychometric data. Only five reported test–retest data. Twenty-six studies\r\nreported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach’s alphas were reported\r\nin 12 studies for the comparative tests (11 with α \u003e 0.7) and four studies for the reference tests (four with\r\nα \u003e 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with\r\nanother assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment\r\nInterview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment\r\ndisorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference\r\nstandard, two studies were found with disorganised attachment at baseline, with one finding raised\r\npsychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model\r\ncould not be justifiably populated. This, alongside other findings, informed research priorities.\r\nLimitations: There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our\r\nhealth economists for long-term sequelae, yielded a limited number of papers.\r\nConclusions: Maternal sensitivity interventions show good outcomes in at-risk populations, but require\r\nfurther research with complex children. The SSP and RDC for attachment disorders remain the reference\r\nstandards for identification until more concurrent and predictive validity research is conducted. A birth\r\ncohort with sequential attachment measures and outcomes across different domains is recommended with\r\nfurther, methodologically sound randomised controlled intervention trials. The main area identified for\r\nfuture work was a need for good-quality RCTs in at-risk groups such as those entering foster care\r\nor adoption.\r\nStudy registration: This study is registered as PROSPERO CRD42011001395.\r\nFunding: The National Institute for Health Research Health Technology Assessment programme.\r\nABSTRACT\r\nNIHR Journals Library www.journalslibrary.nihr.ac.uk\r\nviii","ai_title_tag":"Effectiveness of Parenting Interventions for Attachment Issues"},"translated_abstract":"Background and objectives: Services have variable practices for identifying and providing interventions\r\nfor ‘severe attachment problems’ (disorganised attachment patterns and attachment disorders). Several\r\ngovernment reports have highlighted the need for better parenting interventions in at-risk groups. This\r\nreport was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting\r\ninterventions for children with severe attachment problems (the main review). One supplementary review\r\nexplored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform\r\nhealth economic aspects of the main review.\r\nData sources: A total of 29 electronic databases were searched with additional mechanisms for\r\nidentifying a wide pool of references using the Cochrane methodology. Examples of databases searched\r\ninclude PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process \u0026 Other Non-Indexed\r\nCitations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried\r\nout between 6 and 12 January 2012.\r\nReview methods: Papers identified were screened and data were extracted by two independent\r\nreviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were\r\nused, including quality assessment of diagnostic accuracy studies – version 2 and the Cochrane risk of bias\r\ntool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken.\r\nA health economics analysis was conducted.\r\nResults: The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting\r\ninterventions to improve attachment patterns, and one involving children with reactive attachment\r\ndisorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed\r\nstatistically significant improvement in disorganised attachment. The interventions saw less disorganised\r\nattachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65;\r\np \u003c 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without\r\nvideo feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool\r\ndemonstrating validity or psychometric data. Only five reported test–retest data. Twenty-six studies\r\nreported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach’s alphas were reported\r\nin 12 studies for the comparative tests (11 with α \u003e 0.7) and four studies for the reference tests (four with\r\nα \u003e 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with\r\nanother assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment\r\nInterview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment\r\ndisorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference\r\nstandard, two studies were found with disorganised attachment at baseline, with one finding raised\r\npsychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model\r\ncould not be justifiably populated. This, alongside other findings, informed research priorities.\r\nLimitations: There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our\r\nhealth economists for long-term sequelae, yielded a limited number of papers.\r\nConclusions: Maternal sensitivity interventions show good outcomes in at-risk populations, but require\r\nfurther research with complex children. The SSP and RDC for attachment disorders remain the reference\r\nstandards for identification until more concurrent and predictive validity research is conducted. A birth\r\ncohort with sequential attachment measures and outcomes across different domains is recommended with\r\nfurther, methodologically sound randomised controlled intervention trials. The main area identified for\r\nfuture work was a need for good-quality RCTs in at-risk groups such as those entering foster care\r\nor adoption.\r\nStudy registration: This study is registered as PROSPERO CRD42011001395.\r\nFunding: The National Institute for Health Research Health Technology Assessment programme.\r\nABSTRACT\r\nNIHR Journals Library www.journalslibrary.nihr.ac.uk\r\nviii","internal_url":"https://www.academia.edu/14455901/Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis","translated_internal_url":"","created_at":"2015-07-28T01:09:55.851-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3957654,"work_id":14455901,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942616,"email":"m***y@nyypct.nhs.uk","display_order":-1,"name":"Barry Melissa (NORTH YORKSHIRE AND YORK PCT)","title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and 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Barry","title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis"},{"id":25297724,"work_id":14455901,"tagging_user_id":32190908,"tagged_user_id":34806340,"co_author_invite_id":null,"email":"s***9@york.ac.uk","display_order":8387584,"name":"Simon Gilbody","title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis"},{"id":31105906,"work_id":14455901,"tagging_user_id":47522776,"tagged_user_id":77830027,"co_author_invite_id":6636249,"email":"c***n@nhs.net","display_order":8388096,"name":"Clare Whitton","title":"Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis"}],"downloadable_attachments":[{"id":38313392,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/38313392/thumbnails/1.jpg","file_name":"FullReport-hta19520.pdf","download_url":"https://www.academia.edu/attachments/38313392/download_file","bulk_download_file_name":"Clinical_effectiveness_and_cost_effectiv.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/38313392/FullReport-hta19520-libre.pdf?1438071201=\u0026response-content-disposition=attachment%3B+filename%3DClinical_effectiveness_and_cost_effectiv.pdf\u0026Expires=1738613826\u0026Signature=F6uma1vwlabcU3Sre4rzB5tIpa0z-PaQ0Q1uvPSZN7e7JNK4FiP7jrlwNoZh7EKtckANUkprJEa9C52KVOWWj-Mh7P4JJn61mQyUvd9QfpIR3l-YjpgbnISqhaMyi-qQ0t8R5sgmDZizGxwcLmGFFrzMlmTbsRonSiDcnR0K2Z6Hui5KXyTrKjS0x7HYaGNJmuqpJmCi02AoYW5oP4d3wbjgo8z8cy81RJ0GprbllbUYXN8s3Sppqvdjiu6ET7LU-wJxKK-Mc777vFXn0dyeatgeaAdSe23~xBo4UpHA7tdAQjYkbPpZHE4r6WCDIGiP4Q~kglah2bbldf2iONPgeQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Clinical_effectiveness_and_cost_effectiveness_of_parenting_interventions_for_children_with_severe_attachment_problems_a_systematic_review_and_meta_analysis","translated_slug":"","page_count":380,"language":"en","content_type":"Work","summary":"Background and objectives: Services have variable practices for identifying and providing interventions\r\nfor ‘severe attachment problems’ (disorganised attachment patterns and attachment disorders). Several\r\ngovernment reports have highlighted the need for better parenting interventions in at-risk groups. This\r\nreport was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting\r\ninterventions for children with severe attachment problems (the main review). One supplementary review\r\nexplored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform\r\nhealth economic aspects of the main review.\r\nData sources: A total of 29 electronic databases were searched with additional mechanisms for\r\nidentifying a wide pool of references using the Cochrane methodology. Examples of databases searched\r\ninclude PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process \u0026 Other Non-Indexed\r\nCitations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried\r\nout between 6 and 12 January 2012.\r\nReview methods: Papers identified were screened and data were extracted by two independent\r\nreviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were\r\nused, including quality assessment of diagnostic accuracy studies – version 2 and the Cochrane risk of bias\r\ntool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken.\r\nA health economics analysis was conducted.\r\nResults: The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting\r\ninterventions to improve attachment patterns, and one involving children with reactive attachment\r\ndisorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed\r\nstatistically significant improvement in disorganised attachment. The interventions saw less disorganised\r\nattachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65;\r\np \u003c 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without\r\nvideo feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool\r\ndemonstrating validity or psychometric data. Only five reported test–retest data. Twenty-six studies\r\nreported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach’s alphas were reported\r\nin 12 studies for the comparative tests (11 with α \u003e 0.7) and four studies for the reference tests (four with\r\nα \u003e 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with\r\nanother assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment\r\nInterview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment\r\ndisorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference\r\nstandard, two studies were found with disorganised attachment at baseline, with one finding raised\r\npsychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model\r\ncould not be justifiably populated. This, alongside other findings, informed research priorities.\r\nLimitations: There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our\r\nhealth economists for long-term sequelae, yielded a limited number of papers.\r\nConclusions: Maternal sensitivity interventions show good outcomes in at-risk populations, but require\r\nfurther research with complex children. The SSP and RDC for attachment disorders remain the reference\r\nstandards for identification until more concurrent and predictive validity research is conducted. A birth\r\ncohort with sequential attachment measures and outcomes across different domains is recommended with\r\nfurther, methodologically sound randomised controlled intervention trials. The main area identified for\r\nfuture work was a need for good-quality RCTs in at-risk groups such as those entering foster care\r\nor adoption.\r\nStudy registration: This study is registered as PROSPERO CRD42011001395.\r\nFunding: The National Institute for Health Research Health Technology Assessment programme.\r\nABSTRACT\r\nNIHR Journals Library www.journalslibrary.nihr.ac.uk\r\nviii","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":38313392,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/38313392/thumbnails/1.jpg","file_name":"FullReport-hta19520.pdf","download_url":"https://www.academia.edu/attachments/38313392/download_file","bulk_download_file_name":"Clinical_effectiveness_and_cost_effectiv.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/38313392/FullReport-hta19520-libre.pdf?1438071201=\u0026response-content-disposition=attachment%3B+filename%3DClinical_effectiveness_and_cost_effectiv.pdf\u0026Expires=1738613826\u0026Signature=F6uma1vwlabcU3Sre4rzB5tIpa0z-PaQ0Q1uvPSZN7e7JNK4FiP7jrlwNoZh7EKtckANUkprJEa9C52KVOWWj-Mh7P4JJn61mQyUvd9QfpIR3l-YjpgbnISqhaMyi-qQ0t8R5sgmDZizGxwcLmGFFrzMlmTbsRonSiDcnR0K2Z6Hui5KXyTrKjS0x7HYaGNJmuqpJmCi02AoYW5oP4d3wbjgo8z8cy81RJ0GprbllbUYXN8s3Sppqvdjiu6ET7LU-wJxKK-Mc777vFXn0dyeatgeaAdSe23~xBo4UpHA7tdAQjYkbPpZHE4r6WCDIGiP4Q~kglah2bbldf2iONPgeQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":724,"name":"Economics","url":"https://www.academia.edu/Documents/in/Economics"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":6482,"name":"Meta-Analysis and Systematic Review","url":"https://www.academia.edu/Documents/in/Meta-Analysis_and_Systematic_Review"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":16834,"name":"Attachment Theory","url":"https://www.academia.edu/Documents/in/Attachment_Theory"}],"urls":[{"id":5019605,"url":"http://www.journalslibrary.nihr.ac.uk/hta/volume-19/issue-52#abstract"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="13085101"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/13085101/Autism_Spectrum_Social_Stories_In_Schools_Trial_ASSSIST_study_protocol_for_a_feasibility_randomised_controlled_trial_analysing_clinical_and_cost_effectiveness_of_Social_Stories_in_mainstream_schools"><img alt="Research paper thumbnail of Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost effectiveness of Social Stories in mainstream schools" class="work-thumbnail" src="https://attachments.academia-assets.com/37940494/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/13085101/Autism_Spectrum_Social_Stories_In_Schools_Trial_ASSSIST_study_protocol_for_a_feasibility_randomised_controlled_trial_analysing_clinical_and_cost_effectiveness_of_Social_Stories_in_mainstream_schools">Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost effectiveness of Social Stories in mainstream schools</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/LizCook">Liz Cook</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HannahAinsworth">Hannah Ainsworth</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/JoyAdamson">Joy Adamson</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/LisaDyson">Lisa Dyson</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/VAllgar">Victoria Allgar</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction Current evidence suggests that Social Stories can be effective in tackling problem b...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction Current evidence suggests that Social Stories can be effective in tackling problem behaviours exhibited by children with autism spectrum disorder. Exploring the meaning of behaviour from a child's perspective allows stories to provide social information that is tailored to their needs. Case reports in children with autism have suggested that these stories can lead to a number of benefits including improvements in social interactions and choice making in educational settings. <br /> <br />Methods and analysis The feasibility of clinical and cost-effectiveness of a Social Stories toolkit will be assessed using a randomised control framework. Participants (n=50) will be randomised to either the Social Stories intervention or a comparator group where they will be read standard stories for an equivalent amount of time. Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. Qualitative analysis will ascertain information on perceptions about the feasibility and acceptability of the intervention. <br /> <br />Ethics and dissemination National Health Service Ethics Approval (NHS; ref 11/YH/0340) for the trial protocol has been obtained along with NHS Research and Development permission from Leeds and York Partnership NHS Foundation Trust. All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. At least one article in a peer reviewed journal will be published and research findings presented at relevant conferences. <br /> <br />Trial registration number ISRCTN96286707.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2ec052029ebfcac5751c60a01e44ee37" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37940494,"asset_id":13085101,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37940494/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="13085101"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="13085101"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13085101; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13085101]").text(description); $(".js-view-count[data-work-id=13085101]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13085101; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='13085101']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2ec052029ebfcac5751c60a01e44ee37" } } $('.js-work-strip[data-work-id=13085101]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":13085101,"title":"Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost effectiveness of Social Stories in mainstream schools","translated_title":"","metadata":{"abstract":"Introduction Current evidence suggests that Social Stories can be effective in tackling problem behaviours exhibited by children with autism spectrum disorder. Exploring the meaning of behaviour from a child's perspective allows stories to provide social information that is tailored to their needs. Case reports in children with autism have suggested that these stories can lead to a number of benefits including improvements in social interactions and choice making in educational settings.\r\n\r\nMethods and analysis The feasibility of clinical and cost-effectiveness of a Social Stories toolkit will be assessed using a randomised control framework. Participants (n=50) will be randomised to either the Social Stories intervention or a comparator group where they will be read standard stories for an equivalent amount of time. Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. Qualitative analysis will ascertain information on perceptions about the feasibility and acceptability of the intervention.\r\n\r\nEthics and dissemination National Health Service Ethics Approval (NHS; ref 11/YH/0340) for the trial protocol has been obtained along with NHS Research and Development permission from Leeds and York Partnership NHS Foundation Trust. All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. At least one article in a peer reviewed journal will be published and research findings presented at relevant conferences.\r\n\r\nTrial registration number ISRCTN96286707."},"translated_abstract":"Introduction Current evidence suggests that Social Stories can be effective in tackling problem behaviours exhibited by children with autism spectrum disorder. Exploring the meaning of behaviour from a child's perspective allows stories to provide social information that is tailored to their needs. Case reports in children with autism have suggested that these stories can lead to a number of benefits including improvements in social interactions and choice making in educational settings.\r\n\r\nMethods and analysis The feasibility of clinical and cost-effectiveness of a Social Stories toolkit will be assessed using a randomised control framework. Participants (n=50) will be randomised to either the Social Stories intervention or a comparator group where they will be read standard stories for an equivalent amount of time. Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. Qualitative analysis will ascertain information on perceptions about the feasibility and acceptability of the intervention.\r\n\r\nEthics and dissemination National Health Service Ethics Approval (NHS; ref 11/YH/0340) for the trial protocol has been obtained along with NHS Research and Development permission from Leeds and York Partnership NHS Foundation Trust. All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. At least one article in a peer reviewed journal will be published and research findings presented at relevant conferences.\r\n\r\nTrial registration number ISRCTN96286707.","internal_url":"https://www.academia.edu/13085101/Autism_Spectrum_Social_Stories_In_Schools_Trial_ASSSIST_study_protocol_for_a_feasibility_randomised_controlled_trial_analysing_clinical_and_cost_effectiveness_of_Social_Stories_in_mainstream_schools","translated_internal_url":"","created_at":"2015-06-18T13:37:35.504-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3957400,"work_id":13085101,"tagging_user_id":24191374,"tagged_user_id":33557333,"co_author_invite_id":942569,"email":"l***k@york.ac.uk","affiliation":"University of York","display_order":-1,"name":"Liz Cook","title":"Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled 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schools"}],"downloadable_attachments":[{"id":37940494,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940494/thumbnails/1.jpg","file_name":"BMJ_Open-2014-Wright-1.pdf","download_url":"https://www.academia.edu/attachments/37940494/download_file","bulk_download_file_name":"Autism_Spectrum_Social_Stories_In_School.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940494/BMJ_Open-2014-Wright-1-libre.pdf?1434660060=\u0026response-content-disposition=attachment%3B+filename%3DAutism_Spectrum_Social_Stories_In_School.pdf\u0026Expires=1738613826\u0026Signature=Va651t8m5Mme2~RpMB~5bDyn85sf227S8njJLLSANy5~Rla7zzEmdE6kT0OZqthpsXevqJ9HIQZEGRcDx8UOOY7YyEj3yjHmJfLnzUEZyXVcLGxOWU9EZB81jg9XPSpsH5gBuUhnRAMgYcUx3o-vjfFV6ZuNXBQfqCUazn-~ZkjChXnqtplVkePCgSRkYSvOQRnOZMKDlDsbs0G2mgt~EWjUWOmVSwvIKXlZl9WlukVPwTaLOqM7r0a7RWWDp8xx4Y7rR-ELA9YS6u-vrG9N~a6xk2Oo9-ZVRQQNrKJaYcRdK52UUo5~ipClVQdAYzRklQiMHzduIIiD8PddwXafgQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Autism_Spectrum_Social_Stories_In_Schools_Trial_ASSSIST_study_protocol_for_a_feasibility_randomised_controlled_trial_analysing_clinical_and_cost_effectiveness_of_Social_Stories_in_mainstream_schools","translated_slug":"","page_count":7,"language":"en","content_type":"Work","summary":"Introduction Current evidence suggests that Social Stories can be effective in tackling problem behaviours exhibited by children with autism spectrum disorder. Exploring the meaning of behaviour from a child's perspective allows stories to provide social information that is tailored to their needs. Case reports in children with autism have suggested that these stories can lead to a number of benefits including improvements in social interactions and choice making in educational settings.\r\n\r\nMethods and analysis The feasibility of clinical and cost-effectiveness of a Social Stories toolkit will be assessed using a randomised control framework. Participants (n=50) will be randomised to either the Social Stories intervention or a comparator group where they will be read standard stories for an equivalent amount of time. Statistics will be calculated for recruitment rates, follow-up rates and attrition. Economic analysis will determine appropriate measures of generic health and resource use categories for cost-effectiveness analysis. Qualitative analysis will ascertain information on perceptions about the feasibility and acceptability of the intervention.\r\n\r\nEthics and dissemination National Health Service Ethics Approval (NHS; ref 11/YH/0340) for the trial protocol has been obtained along with NHS Research and Development permission from Leeds and York Partnership NHS Foundation Trust. All adverse events will be closely monitored, documented and reported to the study Data Monitoring Ethics Committee. At least one article in a peer reviewed journal will be published and research findings presented at relevant conferences.\r\n\r\nTrial registration number ISRCTN96286707.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":37940494,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940494/thumbnails/1.jpg","file_name":"BMJ_Open-2014-Wright-1.pdf","download_url":"https://www.academia.edu/attachments/37940494/download_file","bulk_download_file_name":"Autism_Spectrum_Social_Stories_In_School.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940494/BMJ_Open-2014-Wright-1-libre.pdf?1434660060=\u0026response-content-disposition=attachment%3B+filename%3DAutism_Spectrum_Social_Stories_In_School.pdf\u0026Expires=1738613826\u0026Signature=Va651t8m5Mme2~RpMB~5bDyn85sf227S8njJLLSANy5~Rla7zzEmdE6kT0OZqthpsXevqJ9HIQZEGRcDx8UOOY7YyEj3yjHmJfLnzUEZyXVcLGxOWU9EZB81jg9XPSpsH5gBuUhnRAMgYcUx3o-vjfFV6ZuNXBQfqCUazn-~ZkjChXnqtplVkePCgSRkYSvOQRnOZMKDlDsbs0G2mgt~EWjUWOmVSwvIKXlZl9WlukVPwTaLOqM7r0a7RWWDp8xx4Y7rR-ELA9YS6u-vrG9N~a6xk2Oo9-ZVRQQNrKJaYcRdK52UUo5~ipClVQdAYzRklQiMHzduIIiD8PddwXafgQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":2249,"name":"Autism","url":"https://www.academia.edu/Documents/in/Autism"},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health"},{"id":4270,"name":"Autism Spectrum Disorders","url":"https://www.academia.edu/Documents/in/Autism_Spectrum_Disorders"},{"id":4387,"name":"Clinical Trials","url":"https://www.academia.edu/Documents/in/Clinical_Trials"},{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":23550,"name":"Autism (Education)","url":"https://www.academia.edu/Documents/in/Autism_Education_"},{"id":44526,"name":"Feasibility Study","url":"https://www.academia.edu/Documents/in/Feasibility_Study"},{"id":1223929,"name":"Autism Spectrum Treatment","url":"https://www.academia.edu/Documents/in/Autism_Spectrum_Treatment"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="13084982"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/13084982/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial"><img alt="Research paper thumbnail of Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial" class="work-thumbnail" src="https://attachments.academia-assets.com/37940478/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/13084982/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial">Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/JoyAdamson">Joy Adamson</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/VAllgar">Victoria Allgar</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://york.academia.edu/LisaDyson">Lisa Dyson</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: The 1 year prevalence of depression in adolescents is about 2%. Treatment with ant...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: The 1 year prevalence of depression in <br />adolescents is about 2%. Treatment with antidepressant <br />medication is not recommended for initial treatment in <br />young people due to concerns over high side effects, <br />poor efficacy and addictive potential. Evidence suggests <br />that cognitive behaviour therapy (CBT) is an effective <br />treatment for depression and is currently one of the <br />main treatment options recommended in adolescents. <br />Given the affinity young people have with information <br />technology they may be treated effectively, more widely <br />and earlier in their illness evolution using computeradministered <br />CBT (CCBT). Currently little is known <br />about the clinical and resource implications of <br />implementing CCBT within the National Health Service <br />for adolescents with low mood/depression. We aim to <br />establish the feasibility of running a fully powered <br />randomised controlled trial (RCT). <br />Methods and analysis: Adolescents aged 12–18 with <br />low mood/depression, (scoring ≥20 on the Mood and <br />Feelings Questionnaire (MFQ)), will be approached to <br />participate. Consenting participants will be randomised <br />to either a CCBT programme (Stressbusters) or <br />accessing selected websites providing information <br />about low mood/depression. The primary outcome <br />measure will be the Beck Depression Inventory (BDI). <br />Participants will also complete generic health measures <br />(EQ5D-Y, HUI2) and resource use questionnaires to <br />examine the feasibility of cost-effectiveness analysis. <br />Questionnaires will be completed at baseline, 4 and 12- <br />month follow-ups. Progress and risk will be monitored <br />via the MFQ administered at each treatment session. <br />The acceptability of a CCBT programme to adolescents; <br />and the willingness of clinicians to recruit participants <br />and of participants to be randomised, recruitment rates, <br />attrition rates and questionnaire completion rates will be <br />collected for feasibility analysis. We will estimate <br />‘numbers needed’ to plan a fully powered RCT of clinical <br />and cost-effectiveness. <br />Ethics and dissemination: The current trial protocol <br />received a favourable ethical opinion from Leeds <br />(West) Research and Ethics Committee. (Reference: <br />10/H1307/137). <br />Trial registration number: ISRCTN31219579.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6e6366e2ba9c5c87cf6af4ec05e18db0" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37940478,"asset_id":13084982,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37940478/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="13084982"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="13084982"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13084982; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13084982]").text(description); $(".js-view-count[data-work-id=13084982]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13084982; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='13084982']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6e6366e2ba9c5c87cf6af4ec05e18db0" } } $('.js-work-strip[data-work-id=13084982]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":13084982,"title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial","translated_title":"","metadata":{"abstract":"Introduction: The 1 year prevalence of depression in\r\nadolescents is about 2%. Treatment with antidepressant\r\nmedication is not recommended for initial treatment in\r\nyoung people due to concerns over high side effects,\r\npoor efficacy and addictive potential. Evidence suggests\r\nthat cognitive behaviour therapy (CBT) is an effective\r\ntreatment for depression and is currently one of the\r\nmain treatment options recommended in adolescents.\r\nGiven the affinity young people have with information\r\ntechnology they may be treated effectively, more widely\r\nand earlier in their illness evolution using computeradministered\r\nCBT (CCBT). Currently little is known\r\nabout the clinical and resource implications of\r\nimplementing CCBT within the National Health Service\r\nfor adolescents with low mood/depression. We aim to\r\nestablish the feasibility of running a fully powered\r\nrandomised controlled trial (RCT).\r\nMethods and analysis: Adolescents aged 12–18 with\r\nlow mood/depression, (scoring ≥20 on the Mood and\r\nFeelings Questionnaire (MFQ)), will be approached to\r\nparticipate. Consenting participants will be randomised\r\nto either a CCBT programme (Stressbusters) or\r\naccessing selected websites providing information\r\nabout low mood/depression. The primary outcome\r\nmeasure will be the Beck Depression Inventory (BDI).\r\nParticipants will also complete generic health measures\r\n(EQ5D-Y, HUI2) and resource use questionnaires to\r\nexamine the feasibility of cost-effectiveness analysis.\r\nQuestionnaires will be completed at baseline, 4 and 12-\r\nmonth follow-ups. Progress and risk will be monitored\r\nvia the MFQ administered at each treatment session.\r\nThe acceptability of a CCBT programme to adolescents;\r\nand the willingness of clinicians to recruit participants\r\nand of participants to be randomised, recruitment rates,\r\nattrition rates and questionnaire completion rates will be\r\ncollected for feasibility analysis. We will estimate\r\n‘numbers needed’ to plan a fully powered RCT of clinical\r\nand cost-effectiveness.\r\nEthics and dissemination: The current trial protocol\r\nreceived a favourable ethical opinion from Leeds\r\n(West) Research and Ethics Committee. (Reference:\r\n10/H1307/137).\r\nTrial registration number: ISRCTN31219579."},"translated_abstract":"Introduction: The 1 year prevalence of depression in\r\nadolescents is about 2%. Treatment with antidepressant\r\nmedication is not recommended for initial treatment in\r\nyoung people due to concerns over high side effects,\r\npoor efficacy and addictive potential. Evidence suggests\r\nthat cognitive behaviour therapy (CBT) is an effective\r\ntreatment for depression and is currently one of the\r\nmain treatment options recommended in adolescents.\r\nGiven the affinity young people have with information\r\ntechnology they may be treated effectively, more widely\r\nand earlier in their illness evolution using computeradministered\r\nCBT (CCBT). Currently little is known\r\nabout the clinical and resource implications of\r\nimplementing CCBT within the National Health Service\r\nfor adolescents with low mood/depression. We aim to\r\nestablish the feasibility of running a fully powered\r\nrandomised controlled trial (RCT).\r\nMethods and analysis: Adolescents aged 12–18 with\r\nlow mood/depression, (scoring ≥20 on the Mood and\r\nFeelings Questionnaire (MFQ)), will be approached to\r\nparticipate. Consenting participants will be randomised\r\nto either a CCBT programme (Stressbusters) or\r\naccessing selected websites providing information\r\nabout low mood/depression. The primary outcome\r\nmeasure will be the Beck Depression Inventory (BDI).\r\nParticipants will also complete generic health measures\r\n(EQ5D-Y, HUI2) and resource use questionnaires to\r\nexamine the feasibility of cost-effectiveness analysis.\r\nQuestionnaires will be completed at baseline, 4 and 12-\r\nmonth follow-ups. Progress and risk will be monitored\r\nvia the MFQ administered at each treatment session.\r\nThe acceptability of a CCBT programme to adolescents;\r\nand the willingness of clinicians to recruit participants\r\nand of participants to be randomised, recruitment rates,\r\nattrition rates and questionnaire completion rates will be\r\ncollected for feasibility analysis. We will estimate\r\n‘numbers needed’ to plan a fully powered RCT of clinical\r\nand cost-effectiveness.\r\nEthics and dissemination: The current trial protocol\r\nreceived a favourable ethical opinion from Leeds\r\n(West) Research and Ethics Committee. (Reference:\r\n10/H1307/137).\r\nTrial registration number: ISRCTN31219579.","internal_url":"https://www.academia.edu/13084982/Computerised_cognitive_behaviour_therapy_for_depression_in_adolescents_study_protocol_for_a_feasibility_randomised_controlled_trial","translated_internal_url":"","created_at":"2015-06-18T13:34:33.335-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3957458,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942581,"email":"s***y@hyms.ac.uk","display_order":-1,"name":"Simon Gilbody","title":"Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial"},{"id":3957459,"work_id":13084982,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":333911,"email":"b***y@sms.ed.ac.uk","display_order":1,"name":"Ben 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The 1 year prevalence of depression in\r\nadolescents is about 2%. Treatment with antidepressant\r\nmedication is not recommended for initial treatment in\r\nyoung people due to concerns over high side effects,\r\npoor efficacy and addictive potential. Evidence suggests\r\nthat cognitive behaviour therapy (CBT) is an effective\r\ntreatment for depression and is currently one of the\r\nmain treatment options recommended in adolescents.\r\nGiven the affinity young people have with information\r\ntechnology they may be treated effectively, more widely\r\nand earlier in their illness evolution using computeradministered\r\nCBT (CCBT). Currently little is known\r\nabout the clinical and resource implications of\r\nimplementing CCBT within the National Health Service\r\nfor adolescents with low mood/depression. We aim to\r\nestablish the feasibility of running a fully powered\r\nrandomised controlled trial (RCT).\r\nMethods and analysis: Adolescents aged 12–18 with\r\nlow mood/depression, (scoring ≥20 on the Mood and\r\nFeelings Questionnaire (MFQ)), will be approached to\r\nparticipate. Consenting participants will be randomised\r\nto either a CCBT programme (Stressbusters) or\r\naccessing selected websites providing information\r\nabout low mood/depression. The primary outcome\r\nmeasure will be the Beck Depression Inventory (BDI).\r\nParticipants will also complete generic health measures\r\n(EQ5D-Y, HUI2) and resource use questionnaires to\r\nexamine the feasibility of cost-effectiveness analysis.\r\nQuestionnaires will be completed at baseline, 4 and 12-\r\nmonth follow-ups. Progress and risk will be monitored\r\nvia the MFQ administered at each treatment session.\r\nThe acceptability of a CCBT programme to adolescents;\r\nand the willingness of clinicians to recruit participants\r\nand of participants to be randomised, recruitment rates,\r\nattrition rates and questionnaire completion rates will be\r\ncollected for feasibility analysis. We will estimate\r\n‘numbers needed’ to plan a fully powered RCT of clinical\r\nand cost-effectiveness.\r\nEthics and dissemination: The current trial protocol\r\nreceived a favourable ethical opinion from Leeds\r\n(West) Research and Ethics Committee. (Reference:\r\n10/H1307/137).\r\nTrial registration number: ISRCTN31219579.","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":37940478,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940478/thumbnails/1.jpg","file_name":"BMJ_Open-2014-Wright-.pdf","download_url":"https://www.academia.edu/attachments/37940478/download_file","bulk_download_file_name":"Computerised_cognitive_behaviour_therapy.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940478/BMJ_Open-2014-Wright--libre.pdf?1434659857=\u0026response-content-disposition=attachment%3B+filename%3DComputerised_cognitive_behaviour_therapy.pdf\u0026Expires=1738613826\u0026Signature=XmzrGyCsoj3s2B5fJQJCzXOlGzEMY9C0gvm2aoSoNiEqgRuVzcn06ESP9-~QHzl6tz9cADQbINLPUOp~VhYv7k36gvDVVZgSvAkvegvSgQ46VWDZqNQWh3d3IA0D22MeRuQfRM6CbsL7hQdwSm4oJycR-1rZOR7ytbE-dhBvD5G4eUAGGFSja-cZqwWMiVQ3ZcS5lOXWh-Gdjeocct47WzMj4riTjcwBMVgti0y8JoWFijANobaceuPYfQrwz9sibWXI8xXPGI4n7IKKChDJhLJLM2F3PG4LD2Qj1bwgbIodVK5K0i2hbppZNAUY~pkc5VIIhJwB3T2NSJvnejzT8A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":230,"name":"Cognitive Behavioral Therapy","url":"https://www.academia.edu/Documents/in/Cognitive_Behavioral_Therapy"},{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health"},{"id":4387,"name":"Clinical Trials","url":"https://www.academia.edu/Documents/in/Clinical_Trials"},{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":44526,"name":"Feasibility Study","url":"https://www.academia.edu/Documents/in/Feasibility_Study"},{"id":65944,"name":"eHealth","url":"https://www.academia.edu/Documents/in/eHealth"},{"id":189859,"name":"eHealth, health informatics, Healthcare Technology","url":"https://www.academia.edu/Documents/in/eHealth_health_informatics_Healthcare_Technology"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="13084418"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/13084418/Self_hypnosis_for_intrapartum_pain_management_in_pregnant_nulliparous_women_a_randomised_controlled_trial_of_clinical_effectiveness"><img alt="Research paper thumbnail of Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness" class="work-thumbnail" src="https://attachments.academia-assets.com/37940367/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/13084418/Self_hypnosis_for_intrapartum_pain_management_in_pregnant_nulliparous_women_a_randomised_controlled_trial_of_clinical_effectiveness">Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://uclan.academia.edu/SooDowne">Soo Downe</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/FinlaysonK">K. Finlayson</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HSpiby">H. Spiby</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HinderS">S. Hinder</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Abstract OBJECTIVE: (Primary) To establish the effect of antenatal group self-hypnosis for null...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Abstract <br />OBJECTIVE: <br />(Primary) To establish the effect of antenatal group self-hypnosis for nulliparous women on intra-partum epidural use. <br />DESIGN: <br />Multi-method randomised control trial (RCT). <br />SETTING: <br />Three NHS Trusts. <br />POPULATION: <br />Nulliparous women not planning elective caesarean, without medication for hypertension and without psychological illness. <br />METHODS: <br />Randomisation at 28-32 weeks' gestation to usual care, or to usual care plus brief self-hypnosis training (two × 90-minute groups at around 32 and 35 weeks' gestation; daily audio self-hypnosis CD). Follow up at 2 and 6 weeks postnatal. <br />MAIN OUTCOME MEASURES: <br />Primary: epidural analgesia. Secondary: associated clinical and psychological outcomes; cost analysis. <br />RESULTS: <br />Six hundred and eighty women were randomised. There was no statistically significant difference in epidural use: 27.9% (intervention), 30.3% (control), odds ratio (OR) 0.89 [95% confidence interval (CI): 0.64-1.24], or in 27 of 29 pre-specified secondary clinical and psychological outcomes. Women in the intervention group had lower actual than anticipated levels of fear and anxiety between baseline and 2 weeks post natal (anxiety: OR -0.72, 95% CI -1.16 to -0.28, P = 0.001); fear (OR -0.62, 95% CI -1.08 to -0.16, P = 0.009). Postnatal response rates were 67% overall at 2 weeks. The additional cost in the intervention arm per woman was £4.83 (CI -£257.93 to £267.59). <br />CONCLUSIONS: <br />Allocation to two-third-trimester group self-hypnosis training sessions did not significantly reduce intra-partum epidural analgesia use or a range of other clinical and psychological variables. The impact of women's anxiety and fear about childbirth needs further investigation.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6f275c5e2e1ec74adc90fd09975cbac6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37940367,"asset_id":13084418,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37940367/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="13084418"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="13084418"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13084418; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13084418]").text(description); $(".js-view-count[data-work-id=13084418]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13084418; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='13084418']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6f275c5e2e1ec74adc90fd09975cbac6" } } $('.js-work-strip[data-work-id=13084418]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":13084418,"title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness","translated_title":"","metadata":{"abstract":"Abstract\r\nOBJECTIVE:\r\n(Primary) To establish the effect of antenatal group self-hypnosis for nulliparous women on intra-partum epidural use.\r\nDESIGN:\r\nMulti-method randomised control trial (RCT).\r\nSETTING:\r\nThree NHS Trusts.\r\nPOPULATION:\r\nNulliparous women not planning elective caesarean, without medication for hypertension and without psychological illness.\r\nMETHODS:\r\nRandomisation at 28-32 weeks' gestation to usual care, or to usual care plus brief self-hypnosis training (two × 90-minute groups at around 32 and 35 weeks' gestation; daily audio self-hypnosis CD). Follow up at 2 and 6 weeks postnatal.\r\nMAIN OUTCOME MEASURES:\r\nPrimary: epidural analgesia. Secondary: associated clinical and psychological outcomes; cost analysis.\r\nRESULTS:\r\nSix hundred and eighty women were randomised. There was no statistically significant difference in epidural use: 27.9% (intervention), 30.3% (control), odds ratio (OR) 0.89 [95% confidence interval (CI): 0.64-1.24], or in 27 of 29 pre-specified secondary clinical and psychological outcomes. Women in the intervention group had lower actual than anticipated levels of fear and anxiety between baseline and 2 weeks post natal (anxiety: OR -0.72, 95% CI -1.16 to -0.28, P = 0.001); fear (OR -0.62, 95% CI -1.08 to -0.16, P = 0.009). Postnatal response rates were 67% overall at 2 weeks. The additional cost in the intervention arm per woman was £4.83 (CI -£257.93 to £267.59).\r\nCONCLUSIONS:\r\nAllocation to two-third-trimester group self-hypnosis training sessions did not significantly reduce intra-partum epidural analgesia use or a range of other clinical and psychological variables. The impact of women's anxiety and fear about childbirth needs further investigation.\r\n"},"translated_abstract":"Abstract\r\nOBJECTIVE:\r\n(Primary) To establish the effect of antenatal group self-hypnosis for nulliparous women on intra-partum epidural use.\r\nDESIGN:\r\nMulti-method randomised control trial (RCT).\r\nSETTING:\r\nThree NHS Trusts.\r\nPOPULATION:\r\nNulliparous women not planning elective caesarean, without medication for hypertension and without psychological illness.\r\nMETHODS:\r\nRandomisation at 28-32 weeks' gestation to usual care, or to usual care plus brief self-hypnosis training (two × 90-minute groups at around 32 and 35 weeks' gestation; daily audio self-hypnosis CD). Follow up at 2 and 6 weeks postnatal.\r\nMAIN OUTCOME MEASURES:\r\nPrimary: epidural analgesia. Secondary: associated clinical and psychological outcomes; cost analysis.\r\nRESULTS:\r\nSix hundred and eighty women were randomised. There was no statistically significant difference in epidural use: 27.9% (intervention), 30.3% (control), odds ratio (OR) 0.89 [95% confidence interval (CI): 0.64-1.24], or in 27 of 29 pre-specified secondary clinical and psychological outcomes. Women in the intervention group had lower actual than anticipated levels of fear and anxiety between baseline and 2 weeks post natal (anxiety: OR -0.72, 95% CI -1.16 to -0.28, P = 0.001); fear (OR -0.62, 95% CI -1.08 to -0.16, P = 0.009). Postnatal response rates were 67% overall at 2 weeks. The additional cost in the intervention arm per woman was £4.83 (CI -£257.93 to £267.59).\r\nCONCLUSIONS:\r\nAllocation to two-third-trimester group self-hypnosis training sessions did not significantly reduce intra-partum epidural analgesia use or a range of other clinical and psychological variables. The impact of women's anxiety and fear about childbirth needs further investigation.\r\n","internal_url":"https://www.academia.edu/13084418/Self_hypnosis_for_intrapartum_pain_management_in_pregnant_nulliparous_women_a_randomised_controlled_trial_of_clinical_effectiveness","translated_internal_url":"","created_at":"2015-06-18T13:16:34.490-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24191374,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":3957782,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":7126,"co_author_invite_id":null,"email":"s***e@uclan.ac.uk","affiliation":"University of Central Lancashire","display_order":-1,"name":"Soo Downe","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957783,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":44705351,"co_author_invite_id":942648,"email":"k***1@uclan.ac.uk","display_order":1,"name":"K. Finlayson","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957784,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":72278626,"co_author_invite_id":942649,"email":"c***n@elht.nhs.uk","display_order":2,"name":"C. Melvin","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957785,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":33441025,"co_author_invite_id":942650,"email":"h***y@nottingham.ac.uk","display_order":3,"name":"H. Spiby","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957786,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942643,"email":"s***0@york.ac.uk","display_order":4,"name":"S. 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Hinder","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957790,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942653,"email":"v***r@uhsm.nhs.uk","display_order":8,"name":"V. Miller","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957791,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":null,"co_author_invite_id":942654,"email":"p***e@liverpool.ac.uk","display_order":9,"name":"P. Slade","title":"Self-hypnosis for intrapartum pain management in pregnant nulliparous women: a randomised controlled trial of clinical effectiveness"},{"id":3957792,"work_id":13084418,"tagging_user_id":24191374,"tagged_user_id":134981544,"co_author_invite_id":942655,"email":"a***s@liverpool.ac.uk","display_order":10,"name":"A. 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Follow up at 2 and 6 weeks postnatal.\r\nMAIN OUTCOME MEASURES:\r\nPrimary: epidural analgesia. Secondary: associated clinical and psychological outcomes; cost analysis.\r\nRESULTS:\r\nSix hundred and eighty women were randomised. There was no statistically significant difference in epidural use: 27.9% (intervention), 30.3% (control), odds ratio (OR) 0.89 [95% confidence interval (CI): 0.64-1.24], or in 27 of 29 pre-specified secondary clinical and psychological outcomes. Women in the intervention group had lower actual than anticipated levels of fear and anxiety between baseline and 2 weeks post natal (anxiety: OR -0.72, 95% CI -1.16 to -0.28, P = 0.001); fear (OR -0.62, 95% CI -1.08 to -0.16, P = 0.009). Postnatal response rates were 67% overall at 2 weeks. The additional cost in the intervention arm per woman was £4.83 (CI -£257.93 to £267.59).\r\nCONCLUSIONS:\r\nAllocation to two-third-trimester group self-hypnosis training sessions did not significantly reduce intra-partum epidural analgesia use or a range of other clinical and psychological variables. The impact of women's anxiety and fear about childbirth needs further investigation.\r\n","owner":{"id":24191374,"first_name":"Dominic","middle_initials":null,"last_name":"Trépel","page_name":"DominicTrépel","domain_name":"leeds","created_at":"2014-12-30T12:16:39.293-08:00","display_name":"Dominic Trépel","url":"https://leeds.academia.edu/DominicTr%C3%A9pel"},"attachments":[{"id":37940367,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37940367/thumbnails/1.jpg","file_name":"Downe_et_al-2015-BJOG-_An_International_Journal_of_Obstetrics___Gynaecology_2.pdf","download_url":"https://www.academia.edu/attachments/37940367/download_file","bulk_download_file_name":"Self_hypnosis_for_intrapartum_pain_manag.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37940367/Downe_et_al-2015-BJOG-_An_International_Journal_of_Obstetrics___Gynaecology_2-libre.pdf?1434658886=\u0026response-content-disposition=attachment%3B+filename%3DSelf_hypnosis_for_intrapartum_pain_manag.pdf\u0026Expires=1738613826\u0026Signature=UpRzO2uY3kLI4qKQofZbpc1ZtbMDQDt~2RwIk-IHJv2I9U~y3rBfv15KF0VpyBDfwhQxuxQKaLoLsbQSVMeSPKxx3AYKQdTjPiJbrvDuvANGGZE7VpX~QWn82F4Rgcf~cWmVj-A1ExclvmfO7n5fXHE0UWLSyejv4T070dpHp~dNoLucILgDn094gW36BhxL39kxX9qIiJ245m-mSNIe3wgJOjE0wx4~kjtg57xH2wynMa27CrrHGIR7ak2NEStTjjAY6VrB4xYRgo7xLYMwGm2g-h82MVaVdhKobh9C-7S0QB8dtyIGpq4jQiMIR8QHuv-mXlmiSc5ZxgQlMevNkQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"},{"id":1292,"name":"Health Economics","url":"https://www.academia.edu/Documents/in/Health_Economics"},{"id":4387,"name":"Clinical Trials","url":"https://www.academia.edu/Documents/in/Clinical_Trials"},{"id":9747,"name":"Hypnosis (Psychology)","url":"https://www.academia.edu/Documents/in/Hypnosis_Psychology_"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":40165,"name":"Pain Management","url":"https://www.academia.edu/Documents/in/Pain_Management"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy"},{"id":103289,"name":"Gynecology and Obstetrics","url":"https://www.academia.edu/Documents/in/Gynecology_and_Obstetrics"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="13084299"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/13084299/An_Economic_Analysis_of_Home_Care_Services"><img alt="Research paper thumbnail of An Economic Analysis of Home Care Services" class="work-thumbnail" src="https://attachments.academia-assets.com/38962170/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/13084299/An_Economic_Analysis_of_Home_Care_Services">An Economic Analysis of Home Care Services</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The Health Service Executive will consider how best to configure resources currently invested in ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The Health Service Executive will consider how best to configure resources currently invested in home care packages and respite care so as to facilitate people with dementia to continue living in their own homes and communities for as long as possible and to improve the supports available for carers.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8bb5e7c7d1024e5b225e6a2b5a68ebc9" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38962170,"asset_id":13084299,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38962170/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="13084299"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="13084299"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13084299; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="12695251"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/12695251/CASPER_plus_CollAborative_care_in_Screen_Positive_EldeRs_with_major_depressive_disorder_study_protocol_for_a_randomised_controlled_trial"><img alt="Research paper thumbnail of CASPER plus (CollAborative care in Screen-Positive EldeRs with major depressive disorder): study protocol for a randomised controlled trial" class="work-thumbnail" src="https://attachments.academia-assets.com/37801831/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/12695251/CASPER_plus_CollAborative_care_in_Screen_Positive_EldeRs_with_major_depressive_disorder_study_protocol_for_a_randomised_controlled_trial">CASPER plus (CollAborative care in Screen-Positive EldeRs with major depressive disorder): study protocol for a randomised controlled trial</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/KarenOverend">Karen Overend</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/shaistameer">shaista meer</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/JohnHolmes">John Holmes</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/HelenLewis11">Helen Lewis</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/RebeccaWoodhouse">Rebecca Woodhouse</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/McMillanDean">Dean McMillan</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/CarolynChewgraham">Carolyn Chew-graham</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/BaileyDella">Della Bailey</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/KBosanquet">Kate Bosanquet</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/GemmaTraviss">Gemma Traviss</a></span></div><div class="wp-workCard_item"><span>Trials</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Depression accounts for the greatest disease burden of all mental health disorders, c...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Depression accounts for the greatest disease burden of all mental health disorders, contributes heavily to healthcare costs, and by 2020 is set to become the second largest cause of global disability. Although 10% to 16% of people aged 65 years and over are likely to experience depressive symptoms, the condition is under-diagnosed and often inadequately treated in primary care. Later-life depression is associated with chronic illness and disability, cognitive impairment and social isolation. With a progressively ageing population it becomes increasingly important to refine strategies to identity and manage depression in older people. Currently, management may be limited to the prescription of antidepressants where there may be poor concordance; older people may lack awareness of psychosocial interventions and general practitioners may neglect to offer this treatment option. Methods/design: CASPER Plus is a multi-centre, randomised controlled trial of a collaborative care intervention for individuals aged 65 years and over experiencing moderate to severe depression. Selected practices in the North of England identify potentially eligible patients and invite them to participate in the study. A diagnostic interview is carried out and participants with major depressive disorder are randomised to either collaborative care or usual care. The recruitment target is 450 participants. The intervention, behavioural activation and medication management in a collaborative care framework, has been adapted to meet the complex needs of older people. It is delivered over eight to 10 weekly sessions by a case manager liaising with general practitioners. The trial aims to evaluate the clinical and cost effectiveness of collaborative care in addition to usual GP care versus usual GP care alone. The primary clinical outcome, depression severity, will be measured with the Patient Health Questionnaire-9 (PHQ-9) at baseline, 4, 12 and 18 months. Cost effectiveness analysis will assess health-related quality of life using the SF-12 and EQ-5D and will examine cost-consequences of collaborative care. A qualitative process evaluation will be undertaken to explore acceptability, gauge the extent to which the intervention is implemented and to explore sustainability beyond the clinical trial. Discussion: Results will add to existing evidence and a positive outcome may lead to the commissioning of this model of service in primary care.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5623bbbb7066da5941a1dcc47303022f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37801831,"asset_id":12695251,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37801831/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="12695251"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="12695251"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12695251; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="12963906"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/12963906/Screening_for_psychological_and_mental_health_difficulties_in_young_people_who_offend_a_systematic_review_and_decision_model"><img alt="Research paper thumbnail of Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/12963906/Screening_for_psychological_and_mental_health_difficulties_in_young_people_who_offend_a_systematic_review_and_decision_model">Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ShehzadAli13">Shehzad Ali</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SimonGilbody">Simon Gilbody</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://yorku.academia.edu/AmandaPerry">Amanda Perry</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/ManeaL">Laura Manea</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/Glanville">Julie Glanville</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://leeds.academia.edu/DominicTr%C3%A9pel">Dominic Trépel</a></span></div><div class="wp-workCard_item"><span>Health Technology Assessment</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">There is policy interest in the screening and treatment of mental health problems in young people...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">There is policy interest in the screening and treatment of mental health problems in young people who offend, but the value of such screening is not yet known. To assess the diagnostic test accuracy of screening measures for mental health problems in young people who offend; to evaluate the clinical effectiveness and cost-effectiveness of screening and treatment; to model estimates of cost; to assess the evidence base for screening against UK National Screening Committee criteria; and to identify future research priorities. In total, 25 electronic databases including MEDLINE, PsycINFO, EMBASE and The Cochrane Library were searched from inception until April 2011. Reverse citation searches of included studies were undertaken and reference list of included studies were examined. Two reviewers independently examined titles and abstracts and extracted data from included studies using a standardised form. The inclusion criteria for the review were (1) population - young offenders (aged 10-21 years); (2) intervention/instrument - screening instruments for mental health problems, implementation of a screening programme or a psychological or pharmacological intervention as part of a clinical trial; (3) comparator - for diagnostic test accuracy studies, any standardised diagnostic interview; for trials, any comparator; (4) outcomes - details of diagnostic test accuracy, mental health outcomes over the short or longer term or measurement of cost data; and (5) study design - for diagnostic test accuracy studies, any design; for screening programmes, randomised controlled trials or controlled trials; for clinical effectiveness studies, randomised controlled trials; for economic studies, economic evaluations of screening strategies or interventions. Of 13,580 studies identified, nine, including eight independent samples, met the inclusion criteria for the diagnostic test accuracy and validity of screening measures review. Screening accuracy was typically modest. No studies examined the clinical effectiveness of screening, although 10 studies were identified that examined the clinical effectiveness of interventions for mental health problems. There were too few studies to make firm conclusions about the clinical effectiveness of treatments in this population. No studies met the inclusion criteria for the assessment of the cost-effectiveness of screening or treatment. An exemplar decision model was developed for depression, which identified a number of the likely key drivers of uncertainty, including the prevalence of unidentified mental health problems, the severity of mental health problems and their relationship to generic measures of outcome and the impact of treatment on recidivism. The information evaluated as part of the review was relevant to five of the UK National Screening Committee criteria. On the basis of the above results, none of the five criteria was met. The conclusions of the review are based on limited evidence. Conclusions are tentative and the decision model should be treated as an exemplar. Evidence on the clinical effectiveness and cost-effectiveness of screening for mental health problems in young people who offend is currently lacking. Future research should consider feasibility trials of clinical interventions to establish important parameters ahead of conducting definitive trials. Future diagnostic studies should compare the diagnostic test accuracy of a range of screening instruments, including those recommended for use in the UK in this population. These studies should be designed to reduce the decision uncertainty identified by the exemplar decision model. This study is registered as PROSPERO CRD42011001466. The National Institute for Health Research Health Technology Assessment programme.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="12963906"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="12963906"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12963906; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12963906]").text(description); $(".js-view-count[data-work-id=12963906]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12963906; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='12963906']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=12963906]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":12963906,"title":"Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model","internal_url":"https://www.academia.edu/12963906/Screening_for_psychological_and_mental_health_difficulties_in_young_people_who_offend_a_systematic_review_and_decision_model","owner_id":32158302,"coauthors_can_edit":true,"owner":{"id":32158302,"first_name":"Julie","middle_initials":null,"last_name":"Glanville","page_name":"Glanville","domain_name":"independent","created_at":"2015-06-13T09:22:31.375-07:00","display_name":"Julie Glanville","url":"https://independent.academia.edu/Glanville"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="10242630"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/10242630/Informal_Cost_of_Dementia_Care_A_Proxy_Good_Valuation_in_Ireland"><img alt="Research paper thumbnail of Informal Cost of Dementia Care – A Proxy-Good Valuation in Ireland" class="work-thumbnail" src="https://attachments.academia-assets.com/36334121/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/10242630/Informal_Cost_of_Dementia_Care_A_Proxy_Good_Valuation_in_Ireland">Informal Cost of Dementia Care – A Proxy-Good Valuation in Ireland</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This paper values the informal costs of dementia care in Ireland based on recently agreed nationa...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This paper values the informal costs of dementia care in Ireland based on recently agreed national costing framework. Drawing on a survey of 270 Irish dementia caregivers, the hours of informal care per day are estimated using variables of individual characteristics, functional limitations and behavioural problems. This estimation finds that an interlinked workcohabitation effect significantly predicts the total informal care available and suggests that increasing burden on carers may alter overall welfare. Given conflict in carers' personal priorities, this paper calculates the market value of formal services to inform equitable distribution of dementia care required. By associating "proxy-good' market values to dementia symptoms requiring specific types of care, the per diem costs of care are estimated to range from €240.96 (early-stage) to €570.04 (late-stage). As burnout is a major risk factor in prolonged care, this paper indicates the formal value of the output of care from a public health service perspective. Policy initiatives to improve technical and allocative efficiency of formal dementia services are required to reduce reliance on informal care.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7a282267484a620b7386c4bc2e48c1f8" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":36334121,"asset_id":10242630,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/36334121/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="10242630"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="10242630"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 10242630; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=10242630]").text(description); $(".js-view-count[data-work-id=10242630]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 10242630; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='10242630']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7a282267484a620b7386c4bc2e48c1f8" } } $('.js-work-strip[data-work-id=10242630]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":10242630,"title":"Informal Cost of Dementia Care – A Proxy-Good Valuation in Ireland","translated_title":"","metadata":{"grobid_abstract":"This paper values the informal costs of dementia care in Ireland based on recently agreed national costing framework. 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