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Search results for: Yongil Kim
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Kim</h1> <div class="card publication-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> The Inhibitory Effect of Weissella koreensis 521 Isolated from Kimchi on 3T3-L1 Adipocyte Differentiation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=KyungBae%20Pi">KyungBae Pi</a>, <a href="https://publications.waset.org/search?q=KiBeom%20Lee"> KiBeom Lee</a>, <a href="https://publications.waset.org/search?q=Yongil%20Kim"> Yongil Kim</a>, <a href="https://publications.waset.org/search?q=Eun-Jung%20Lee"> Eun-Jung Lee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p>Abnormal adipocyte growth, in terms of increased cell numbers and increased cell differentiation, is considered to be a major pathological feature of obesity. Thus, the inhibition of preadipocyte mitogenesis and differentiation could help prevent and suppress obesity. The aim of this study was to assess whether extracts from <em>Weissella koreensis </em>521 cells isolated from kimchi could exert anti-adipogenic effects in 3T3-L1 cells (fat cells). Differentiating 3T3-L1 cells were treated with <em>W. koreensis</em> 521 cell extracts (<em>W. koreensis</em> 521_CE), and cell viability was assessed by MTT assays. At concentrations below 0.2 mg/ml, <em>W. koreensis</em> 521_CE did not exert any cytotoxic effect in 3T3-L1 cells. However, treatment with <em>W</em>.<em> koreensis </em>521_CE significantly inhibited adipocyte differentiation, as assessed by morphological analysis and Oil Red O staining of fat.<em> W. koreensis</em> 521_CE treatment (0.2 mg/ml) also reduced lipid accumulation by 24% in fully differentiated 3T3-L1 adipocytes. These findings collectively indicate that <em>Weissella koreensis </em>521 may help prevent obesity.</p> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Weissella%20koreensis%20521" title="Weissella koreensis 521">Weissella koreensis 521</a>, <a href="https://publications.waset.org/search?q=3T3-L1%20cells" title=" 3T3-L1 cells"> 3T3-L1 cells</a>, <a href="https://publications.waset.org/search?q=adipocyte%20differentiation" title=" adipocyte differentiation"> adipocyte differentiation</a>, <a href="https://publications.waset.org/search?q=obesity." title=" obesity."> obesity.</a> </p> <a href="https://publications.waset.org/9997105/the-inhibitory-effect-of-weissella-koreensis-521-isolated-from-kimchi-on-3t3-l1-adipocyte-differentiation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/9997105/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a 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