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style="--with-sidebar--basis: auto"> <li class="ml15 text13"><a href="/subjects/biophysics.atom" data-track="click" data-track-category="feeds" data-track-action="link:atom" data-track-label="/subjects/biophysics.atom" class="icon icon-left icon-tools-feed-16x16-color pl20">Atom</a></li> <li class="ml15 text13"><a href="/subjects/biophysics.rss" data-track="click" data-track-category="feeds" data-track-action="link:rss" data-track-label="/subjects/biophysics.rss" class="icon icon-left icon-tools-feed-16x16-color pl20">RSS Feed</a></li> </ul> <section class="u-mb-32"> <button class="text-blue pr20 inline-block position-relative icon-rotate icon-arrow-down-12x7-gray link-like js-hide js-mq640-show" data-toggle="collapsible-section" data-target="definition">Definition</button> <p class="tight-line-height js-mq640-hide" id="definition">Biophysics is the study of physical phenomena and physical processes in living things, on scales spanning molecules, cells, tissues and organisms. Biophysicists use the principles and methods of physics to understand biological systems. It is an interdisciplinary science, closely related to quantitative and systems biology.</p> </section> </div> </div> <section class="u-container u-mb-48"><h2 class="c-section-heading">Featured</h2> <ul class="c-list-group c-list-group--lg c-list-group--bordered c-list-group--flush app-article-list-row"> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41563-024-02030-8/MediaObjects/41563_2024_2030_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41563-024-02030-8/MediaObjects/41563_2024_2030_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41563-024-02030-8/MediaObjects/41563_2024_2030_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41563-024-02030-8" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Ions shaping the mechanics of chromosomes in mitosis</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Ions play a key role in governing the viscoelastic properties and mechanical stability of mitotic chromosomes.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Wenmao Huang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Zongqing Lim</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jie Yan</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-29" itemprop="datePublished">29 Oct 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/nmat" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Materials</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 23, P: 1468-1470</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div 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Materials</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 23, P: 1471-1472</div> </div> </article> </li> </ul> </section> <section class="u-container u-mb-48 u-pb-24"> <h2 class="c-section-heading">Related Subjects</h2> <ul class="ma0 clean-list tighten-line-height grid-auto-fill no-row-gap" id="related-subjects-list"> <li class="pb4"> <a href="/subjects/bioenergetics" class="subject-tag-link text14" data-track="click" data-track-action="link:related-subject-tag" data-track-category="subjects" data-track-label="Bioenergetics">Bioenergetics</a> </li> <li class="pb4"> <a href="/subjects/biological-fluorescence" class="subject-tag-link text14" data-track="click" data-track-action="link:related-subject-tag" data-track-category="subjects" data-track-label="Biological fluorescence">Biological fluorescence</a> </li> <li class="pb4"> <a href="/subjects/biopolymers-in-vivo" class="subject-tag-link text14" data-track="click" 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data-track-category="subjects" data-track-label="Single-molecule biophysics">Single-molecule biophysics</a> </li> </ul> <div class="position-absolute position-left grid grid-12 last text-center"> <button class="link-like pill-button-expand position-relative hide js-show-inline" data-toggle="expandable-list" data-target="related-subjects-list" aria-hidden="true"> <span class="icon-rotate position-relative pr20" data-expandable-list-label-toggled="Show less">Show more</span> </button> </div> </section> <section class="u-container u-mb-48"> <h2 class="c-section-heading">Latest Research and Reviews</h2> <ul class="c-list-group c-list-group--lg c-list-group--bordered c-list-group--flush app-article-list-row"> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" 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class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Kainate receptors (KARs) contribute to excitatory neurotransmission, neuronal plasticity and neurological disorders. Here, Gangwar et al. present KAR structures in complex with channel blockers NpTx8, PhTx74, KukoA, and spermine, which become trapped inside the channel upon its closure.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Shanti Pal Gangwar</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Maria V. Yelshanskaya</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Alexander I. Sobolevsky</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Research</span></span><span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-26" itemprop="datePublished">26 Nov 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/ncomms" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Communications</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 15, P: 10257</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41467-024-54305-y/MediaObjects/41467_2024_54305_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-024-54305-y/MediaObjects/41467_2024_54305_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-024-54305-y/MediaObjects/41467_2024_54305_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41467-024-54305-y" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Here, authors present cryo-EM structures and simulations of urea transporter members in resting-, transport-, or inactive-states bound with synthetic competitive, uncompetitive or noncompetitive inhibitor.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Shen-Ming Huang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Zhi-Zhen Huang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jin-Peng Sun</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Research</span></span><span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-26" itemprop="datePublished">26 Nov 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/ncomms" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Communications</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 15, P: 10226</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41467-024-54638-8/MediaObjects/41467_2024_54638_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-024-54638-8/MediaObjects/41467_2024_54638_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-024-54638-8/MediaObjects/41467_2024_54638_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41467-024-54638-8" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Quantitative determination of the spatial distribution of components in single cells with CellDetail</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Tools to determine the spatial distribution of components and their networks inside cells are not well developed. Here, authors provide the open-source 3D-cell-image analysis platform Cell Detection and Analysis of Intensity Lounge (CellDetail) for quantitative distribution analyses.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Tanja Schuster</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Amanda Amoah</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hartmut Geiger</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Research</span></span><span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-26" itemprop="datePublished">26 Nov 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/ncomms" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Communications</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 15, P: 10250</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41598-024-80325-1/MediaObjects/41598_2024_80325_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41598-024-80325-1/MediaObjects/41598_2024_80325_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41598-024-80325-1/MediaObjects/41598_2024_80325_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41598-024-80325-1" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Polarization and reflectance are linked to climate, size and mechanistic constraints in a group of scarab beetles</a> </h3> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Laura Ospina-Rozo</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Iliana Medina</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Devi Stuart-Fox</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Research</span></span><span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-26" itemprop="datePublished">26 Nov 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/srep" data-track="click" data-track-action="clicked journal" data-track-label="link">Scientific Reports</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 14, P: 29349</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41467-024-54325-8/MediaObjects/41467_2024_54325_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-024-54325-8/MediaObjects/41467_2024_54325_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-024-54325-8/MediaObjects/41467_2024_54325_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41467-024-54325-8" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Ultra-fast photoelectron transfer in bimetallic porphyrin optoelectrode for single neuron modulation</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Bimetallic zinc and gold porphyrin self-assembled into 2D nanosheets as nanoscale optoelectrodes. This design achieves exceptional photoelectric performance under visible one-photon and near-infrared two-photon excitation, enabling far-field optical modulation of single neurons.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jian Chen</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Feixiang Chen</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Wenbo Bu</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Research</span></span><span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-26" itemprop="datePublished">26 Nov 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/ncomms" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Communications</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 15, P: 10241</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41467-024-54173-6/MediaObjects/41467_2024_54173_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-024-54173-6/MediaObjects/41467_2024_54173_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-024-54173-6/MediaObjects/41467_2024_54173_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41467-024-54173-6" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Streptolysin O accelerates the conversion of plasminogen to plasmin</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Group A <i>Streptococcus</i> exploits the human fibrinolytic system to promote infection. Here, the authors reveal that the bacterial toxin streptolysin O binds to plasminogen and accelerates its conversion to plasmin, thereby dismantling blood clots and facilitating the spread within the human host.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Di Tang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hamed Khakzad</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Johan Malmstr枚m</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Research</span></span><span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-25" itemprop="datePublished">25 Nov 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/ncomms" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Communications</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 15, P: 10212</div> </div> </article> </li> </ul> <div class="position-left last text-center u-mb-48"> <a href="/search?article_type=protocols,research,reviews&subject=biophysics" class="pill-button inline-block" data-track="click" data-track-action="link:view-all" data-track-category="latest-research" data-track-label="All Research & Reviews"><span>All Research & Reviews</span></a> </div> <section class="u-container u-mb-48"> <div id="div-gpt-ad-article-list-2" class="div-gpt-ad medium-rectangle c-ad c-ad--300x250 advert js-ad hide-print grade-c-hide" 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u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41563-024-02050-4/MediaObjects/41563_2024_2050_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41563-024-02050-4/MediaObjects/41563_2024_2050_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41563-024-02050-4/MediaObjects/41563_2024_2050_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41563-024-02050-4" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Tissues pushing on</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Studies are shedding light on the mechanical properties of cellular tissues and their implications for biological processes.</p> </div> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Editorial</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-29" itemprop="datePublished">29 Oct 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/nmat" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Materials</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 23, P: 1457</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope 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data-track-label="link">Ions shaping the mechanics of chromosomes in mitosis</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Ions play a key role in governing the viscoelastic properties and mechanical stability of mitotic chromosomes.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Wenmao Huang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Zongqing Lim</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jie Yan</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-29" itemprop="datePublished">29 Oct 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/nmat" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Materials</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 23, P: 1468-1470</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41563-024-02033-5/MediaObjects/41563_2024_2033_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41563-024-02033-5/MediaObjects/41563_2024_2033_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 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itemtype="http://schema.org/Person"><span itemprop="name">Kristian Franze</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-29" itemprop="datePublished">29 Oct 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/nmat" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Materials</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 23, P: 1471-1472</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" 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cell cortex consists of a chemical and a mechanical subsystem, but how energy is allocated between them is unknown. Now, measurements of the entropy production rate have revealed what determines the cell cortex鈥檚 energy budget.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Shashi Thutupalli</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-28" itemprop="datePublished">28 Oct 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/nphys" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Physics</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 20, P: 1704-1705</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41594-024-01403-6/MediaObjects/41594_2024_1403_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41594-024-01403-6/MediaObjects/41594_2024_1403_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41594-024-01403-6/MediaObjects/41594_2024_1403_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41594-024-01403-6" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">The guanylate-binding protein GBP1 forms a protein coat that enwraps cytosol-invasive bacteria</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>GBP1 is an important innate immunity component that contributes to the control of cytosol-invasive bacterial pathogens. Using cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET) and biophysical assays, we show how GBP1 oligomers enwrap and remodel the lipopolysaccharide (LPS)-containing membrane of gram-negative bacterial pathogens.</p> </div> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-15" itemprop="datePublished">15 Oct 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/nsmb" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Structural & Molecular Biology</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">P: 1-2</div> </div> </article> </li> <li class="app-article-list-row__item"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs43588-024-00705-5/MediaObjects/43588_2024_705_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs43588-024-00705-5/MediaObjects/43588_2024_705_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs43588-024-00705-5/MediaObjects/43588_2024_705_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s43588-024-00705-5" class="u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Effectively detecting anomalous diffusion via deep learning</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A deep learning algorithm is presented to classify single-particle tracking trajectories into theoretical models of anomalous diffusion and detect if the trajectory is related to a model not originally found within the training dataset.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Adrian Pacheco-Pozo</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Diego Krapf</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">News & Views</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-11" itemprop="datePublished">11 Oct 2024</time> <span class="c-meta__item c-meta__item--block-at-lg"><a href="https://www.nature.com/natcomputsci/" data-track="click" data-track-action="clicked journal" data-track-label="link">Nature Computational Science</a></span> <div class="c-meta__item c-meta__item--block-at-lg" data-test="volume-and-page-info">Volume: 4, P: 731-732</div> </div> </article> </li> </ul> <div class="position-left last text-center"> <a href="/search?article_type=news,editorial,comments-and-opinion,correspondence,news-and-views,research-highlights&subject=biophysics" class="pill-button inline-block" data-track="click" data-track-action="link:view-all" data-track-category="news-and-comment" data-track-label="All News & Comment"><span>All News & Comment</span> </a> </div> </section> </div> <div id="search-menu" class="c-header__dropdown c-header__dropdown--full-width" data-track-component="nature-150-split-header"> <div 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