Schizophrenia - Mass General Advances in Motion

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class="layout-columns__main -padding--vertical -padding--horizontal"> <div class="layout-columns__main__content"> <ul class="content-tease__list"> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/journal.aspx?id=1079" itemprop="url"> Functional MRI Shows Promise for Studying Psychotic Experiences, Testing Treatment</a> </h3> <p itemprop="description"> <p>People with schizophrenia are known to have hippocampal overactivity. Is the same true of people with subthreshold psychosis, and are there clinical implications?</p></p> <p class="content-tease__related"> <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a>, <a href="/neuro/topic.aspx?id=1017" itemprop="relatedLink">Psychiatry</a>, <a href="/neuro/topic.aspx?id=1023" itemprop="relatedLink">Schizophrenia</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2018-07-26" itemprop="datePublished">July 26, 2018</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/video.aspx?id=1020" itemprop="url"> Prenatal Folic Acid and Schizophrenia Prevention</a> </h3> <p itemprop="description"> <p>Joshua Roffman, MD, MMSc, discusses his recent work investigating folic acid’s potential neuroprotective effects that may guard against schizophrenia development.</p></p> <p class="content-tease__related"> <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a>, <a href="/neuro/topic.aspx?id=1017" itemprop="relatedLink">Psychiatry</a>, <a href="/neuro/topic.aspx?id=1023" itemprop="relatedLink">Schizophrenia</a> </p> <p class="content-metadata"> <span class="content-metadata__media -video">Video</span> <time class="date" datetime="2018-07-24" itemprop="datePublished">July 24, 2018</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/article-external.aspx?id=1025" itemprop="url"> Prenatal Exposure to Folic Acid-fortified Foods May Reduce Mental Illness Risk</a> </h3> <p itemprop="description"> <p>Fortification of grain-based foods with folic acid, a practice instituted in the U.S. in the 1990s to prevent neural tube defects in infants, may also reduce the incidence of severe mental illnesses like schizophrenia that initially appear in young adulthood.</p></p> <p class="content-tease__related"> <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a>, <a href="/neuro/topic.aspx?id=1017" itemprop="relatedLink">Psychiatry</a>, <a href="/neuro/topic.aspx?id=1023" itemprop="relatedLink">Schizophrenia</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2018-07-12" itemprop="datePublished">July 12, 2018</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/journal.aspx?id=2107" itemprop="url"> Sex-specific Genetic Effects Across Neuropsychiatric and Behavioral Traits Identified for the First Time</a> </h3> <p itemprop="description"> <p>Jill M. Goldstein, PhD, and Jordan W. Smoller, MD, ScD, of the Department of Psychiatry, and colleagues have reported the first modest evidence of sex-dependent autosomal genetic effects across neuropsychiatric and behavioral traits.</p></p> <p class="content-tease__related"> <a href="/neuro/topic.aspx?id=1031" itemprop="relatedLink">Depression</a>, <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a>, <a href="/neuro/topic.aspx?id=1017" itemprop="relatedLink">Psychiatry</a>, <a href="/neuro/topic.aspx?id=1023" itemprop="relatedLink">Schizophrenia</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2021-12-17" itemprop="datePublished">December 17, 2021</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/article.aspx?id=1097" itemprop="url"> Synaptic Pruning May Play a Role in the Development and Treatment of Schizophrenia</a> </h3> <p itemprop="description"> <p>New research suggests a link between excessive synaptic pruning in human cells and schizophrenia—a major step towards disease prevention.</p></p> <p class="content-tease__related"> <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a>, <a href="/neuro/topic.aspx?id=1017" itemprop="relatedLink">Psychiatry</a>, <a href="/neuro/topic.aspx?id=1023" itemprop="relatedLink">Schizophrenia</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2019-08-02" itemprop="datePublished">August 2, 2019</time> </p> </div> </li> <li class="content-tease__item"> <div class="content-tease" itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/journal.aspx?id=1116" itemprop="url"> Prenatal Folic Acid Exposure Linked to Reduced Risk of Psychosis in Adolescence</a> </h3> <p itemprop="description"> <p>Psychiatrists at Massachusetts General Hospital present the first evidence that prenatal exposure to folic acid has a beneficial effect on postnatal brain development—and reduces the risk of psychotic disorders later in life.</p></p> <p class="content-tease__related"> <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a>, <a href="/neuro/topic.aspx?id=1017" itemprop="relatedLink">Psychiatry</a>, <a href="/neuro/topic.aspx?id=1023" itemprop="relatedLink">Schizophrenia</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2018-10-04" itemprop="datePublished">October 4, 2018</time> </p> </div> </li> </ui> <p class="fat-link__cta u-flush u-text-right"> <a class="fat-link -caret -large" href="https://advances.massgeneral.org/search.aspx?q=*&st=1&topic=schizophrenia&maxResults=15">View All Schizophrenia Updates</a> </p> </div> </div> </section> <section class="-background--grey -padding--vertical -padding--horizontal"> <div class="content-container -width--wide -centered"> <h2 class="section-heading -centered">Schizophrenia Contributors</h2> <ul class="profile-card__list" id="profile-cards"> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <p class="profile-card__content__image"> <img alt="Daphne J. Holt, MD, PhD" itemprop="image" srcset="/assets/images/contributors/daphne-holt_v2_advances.png, /assets/images/contributors/daphne-holt_v2_advancesx2.png 2x" src="/assets/images/contributors/daphne-holt_v2_advances.png"> </p> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1155" itemprop="url">Daphne J. Holt, MD, PhD</a> </h3> <p itemprop="jobTitle"> Co-director, Schizophrenia Clinical and Research Program, Director, Emotion and Social Neuroscience Laboratory; Director, Resilience Program , MGH Research Scholar 2018-2023</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/radiology/article.aspx?id=1589">Radiology Research in a Rapidly Changing World</a> </p> </div> <p class="profile-card__image"> <img alt="Daphne J. Holt, MD, PhD" itemprop="image" srcset="/assets/images/contributors/daphne-holt_v2_advances.png, /assets/images/contributors/daphne-holt_v2_advancesx2.png 2x" src="/assets/images/contributors/daphne-holt_v2_advances.png"> </p> </li> <li class="profile-card" itemscope="" itemtype="http://schema.org/Person"> <div class="profile-card__content"> <p class="profile-card__content__image"> <img alt="Joshua L. Roffman, MD" itemprop="image" srcset="/assets/images/contributors/Joshua_Roffman_advances_2x.png, /assets/images/contributors/Joshua_Roffman_advances.png 2x" src="/assets/images/contributors/Joshua_Roffman_advances_2x.png"> </p> <h3 class="profile-card__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1158" itemprop="url">Joshua L. Roffman, MD, MMSc</a> </h3> <p itemprop="jobTitle"> Director of the Mass General Early Brain Development Initiative</p> <p class="profile-card__article"> <strong>Recent Article</strong><br> <a href="/neuro/journal.aspx?id=2492">Genetic Patterning for Psychopathology Is Distinct in Children and Adults</a> </p> </div> <p class="profile-card__image"> <img alt="Joshua L. Roffman, MD" itemprop="image" srcset="/assets/images/contributors/Joshua_Roffman_advances_2x.png, /assets/images/contributors/Joshua_Roffman_advances.png 2x" src="/assets/images/contributors/Joshua_Roffman_advances_2x.png"> </p> </li> </ul> </div> </section> <div class="content-container -width--xwide -centered specialty-block__wrapper" id="specialty-block"> <style> #specialty-block .specialty-block__image { /* 540px */ background-image: url(/assets/raw/specialty-block/neurocall-out-1x.jpg); } only screen and (-webkit-min-device-pixel-ratio: 2), only screen and (min--moz-device-pixel-ratio: 2), only screen and (-moz-min-device-pixel-ratio: 2), only screen and (-o-min-device-pixel-ratio: 2/1), only screen and (min-device-pixel-ratio: 2), only screen and (min-resolution: 192dpi), only screen and (min-resolution: 2dppx) { #specialty-block .specialty-block__image { /* 1080 width */ background-image: url(/assets/raw/specialty-block/neurocall-out-2x.jpg); } } /* </style> <span 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