NGS-Zielanreicherung und Library Prep

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href="/de/products/ngs/synthetic-viral-controls?tab=monkeypox-controls" class=""> Mpox-Virus-Kontrollen </a> </li> <li class="menu-item"> <a href="/de/products/ngs/synthetic-viral-controls?tab=sars-cov-2-controls" class=""> SARS-COV-2-Kontrollen </a> </li> <li class="menu-item"> <a href="/de/products/ngs/synthetic-viral-controls?tab=respiratory-virus-controls" class=""> Atemwegsvirus-Kontrollen </a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded level-2-category-section" data-column-position=1 data-column-v-weight=1> <div class="level-2-category-section "> <span class="menu-item menu-item--expanded level-2-category-section level-2-category-item"> Festpanels </span> <ul class="menu menu-level-3"> <li class="menu-item"> <a href="/de/products/ngs/fixed-panels/exome2" class=""> Exome 2.0 </a> </li> <li class="menu-item"> <a href="/de/products/ngs/fixed-panels/human-comprehensive-exome" class=""> Human Comprehensive Exome </a> </li> <li class="menu-item"> <a 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Mehr erfahren >"> </div> <p>Twist-Workflow zur Gesamtexom-Libraryvorbereitung. Mehr erfahren ></p> </a> </div> <div class="primary-menu__dropdown-content" data-tab-drawer-4 data-index="data-tab-drawer-4"> <div class="primary-menu__dropdown-columns"> <h2> <a href="/de/products/libraries"> <img src="https://www.twistbioscience.com/sites/default/files/2021-05/icon-libraries.png" alt="Variant Libraries"> Variant Libraries </a> </h2> <ul class="sub-nav-columns total-columns-2" data-sub-nav-columns="2"> <li data-sub-nav-column="1"></li> <li data-sub-nav-column="2"></li> </ul> <a href="/de/get-quote" class="main-action">Jetzt bestellen</a> <ul class="menu menu-level-2"> <li class="menu-item" data-column-position=1 data-column-v-weight=1> <a href="/de/tcr-libraries" class="menu-item level-2-category-item"> TCR-Libraries <span class="menu-link-new">Neu</span> </a> </li> <li class="menu-item" data-column-position=1 data-column-v-weight=1> <a href="/de/products/libraries/combinatorial-variant-library" class="menu-item level-2-category-item"> CVL </a> </li> <li 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level-2-category-item"> Flüssigbiopsie </span> <ul class="menu menu-level-3"> <li class="menu-item"> <a href="/de/products/ngs/twist-cfdna-pan-cancer-reference-standards" class=""> cfDNA Pan-Cancer Reference Standards v2<span class="menu-link-new">Neu</span> </a> </li> </ul> </div> </li> <li class="menu-item menu-item--expanded level-2-category-section" data-column-position=1 data-column-v-weight=1> <div class="level-2-category-section "> <a href="/de/products/ngs/synthetic-viral-controls" class="menu-item menu-item--expanded level-2-category-section level-2-category-item"> Infektionskrankheit </a> <ul class="menu menu-level-3"> <li class="menu-item"> <a href="/de/products/ngs/synthetic-viral-controls?tab=respiratory-virus-controls" class=""> Atemwegsvirus-Kontrollen </a> </li> <li class="menu-item"> <a href="/de/products/ngs/synthetic-viral-controls?tab=sars-cov-2-controls" class=""> SARS-COV-2-Kontrollen </a> </li> <li class="menu-item"> <a 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src="https://www.twistbioscience.com/sites/default/files/2021-05/biopharma-global-213x136%402x_0.png" alt="Lesen Sie unser neues E-Book zur Antikörperidentifizierung und <br>-entwicklung."> </div> <p>Lesen Sie unser neues E-Book zur Antikörperidentifizierung und <br>-entwicklung.</p> </a> </div> </div> </div> </div> </li> <li class="menu-item menu-item--expanded js-primary-menu-wide-mode"> <span title="" id="" name="" rel="" style="" target="" accesskey="">Anwendungen</span> <div data-primary-nav-subnav-container class="wide-menu-sub-navigation"> <div class="primary-nav__drawer-side-bar"> <div class="menu-dropdown menu-dropdown-0"> <ul class="menu menu-level-1" data-tabs > <li class="menu-item menu-item--expanded" data-tab="data-tab-drawer-1" > <a href="https://www.twistbioscience.com/de/good-fight-june-6"> <span>Krebsforschung</span> </a> </li> <li class="menu-item menu-item--large-icon" > <a href="/de/products/storage"> <span>DNA-Datenspeicherung</span> </a> </li> <li 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src="https://www.twistbioscience.com/sites/default/files/2022-06/personalized-sequencing-promo-thumbnail-426x272_0.png" alt="Erfahren Sie mehr über das Twist MRD Rapid 500 Panel."> </div> <p>Erfahren Sie mehr über das Twist MRD Rapid 500 Panel.</p> </a> </div> <div class="primary-menu__dropdown-content" data-tab-drawer-3 data-index="data-tab-drawer-3"> <div class="primary-menu__dropdown-columns"> <h2> <a href="https://www.twistbioscience.com/de/drug-discovery"> Tools für die Arzneimittelforschung </a> </h2> <ul class="sub-nav-columns total-columns-3" data-sub-nav-columns="3"> <li data-sub-nav-column="1"></li> <li data-sub-nav-column="2"></li> <li data-sub-nav-column="3"></li> </ul> <ul class="menu menu-level-2"> <li class="menu-item" data-column-position=1 data-column-v-weight=1> <a href="/de/products/antibody-discovery/single-domain-vhh-antibody-discovery" class="menu-item level-2-category-item"> VHH-Antikörperidentifizierung </a> </li> <li class="menu-item menu-item--expanded 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</aside> <div id="main-wrapper" class="layout-main-wrapper clearfix"> <div id="main"> <div class="row-offcanvas row-offcanvas-left clearfix"> <main class="main-content col" id="content" role="main"> <section class="section"> <a id="main-content" tabindex="-1"></a> <div data-drupal-messages-fallback class="hidden"></div> <div id="block-twist-barrio-content" class="block block-system block-system-main-block"> <div class="content"> <style type="text/css"> .product__banner { background: url(https://www.twistbioscience.com/sites/default/files/2019-12/ngsbackground.png) center no-repeat !important; background-size: cover !important; } </style> <div data-history-node-id="4546" about="/products/ngs" class="product-parent node node--type-product-parent node--view-mode-full"><div class="product__banner product__banner__style-forest "><div class="container"><div class="product__banner__wrapper"><div class="product-parent__image"><img srcset="https://www.twistbioscience.com/sites/default/files/styles/original/public/2020-08/NGS.png 1x" width="400" height="448" src="https://www.twistbioscience.com/sites/default/files/2020-08/NGS.png" alt="" loading="lazy" typeof="foaf:Image" /></div><div class="product-parent__banner-text"><h1>NGS</h1><p>Erzielen Sie eine überlegene Anreicherungseffizienz mit Twist Bioscience NGS-Zielanreicherungslösungen. Gezielte Sequenzierung macht mit optimiertem Anreicherungsworkflow und einfacher Anpassung des Panel-Inhalts einen Schritt nach vorne</p></div></div></div></div><div class="container"><div class="row"><div class="product_sub_menu"></div></div></div><div class="product__content product_content__style-forest"><div class="field field--name-field-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><section class="section-background ngs-icon-text-wrapper" style="background-color:transparent;background-image: url(https://www.twistbioscience.com/de/sites/default/files/2020-01/bg.svg)"><div class="clearfix component-paragraph paragraph paragraph--type--section paragraph--view-mode--default"><div class="section-wrapper container"><div class="row"><div class="paragraph col--bleed col-lg-3 col-sm-3 col-12 paragraph--type--column paragraph--view-mode--default"><div class="tile column-background center " style="background-color:transparent; "><div class="field field--name-field-paragraph-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--icon-with-text paragraph--view-mode--default image-top background" style="background-color:transparent"><div class="inner-wrapper text-align-center"><div class="field field--name-field-icon field--type-image field--label-hidden field__item"><img src="/de/sites/default/files/2020-08/fast-green-2_0.svg" alt="" loading="lazy" typeof="foaf:Image" /></div><div class="clearfix text-formatted field field--name-field-html field--type-text-long field--label-hidden field__item"><p class="text-align-center"><strong>Vom Sampling zum Sequenzer in nur einem Tag</strong></p><p class="text-align-center">Zuverlässige dsDNA-Sonden, verifiziert durch NGS-QK</p></div></div></div></div></div></div></div><div class="paragraph col--bleed col-lg-3 col-sm-3 col-12 paragraph--type--column paragraph--view-mode--default"><div class="tile column-background text-align-center " style="background-color:transparent; "><div class="field field--name-field-paragraph-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--icon-with-text paragraph--view-mode--default image-top background" style="background-color:transparent"><div class="inner-wrapper text-align-center"><div class="field field--name-field-icon field--type-image field--label-hidden field__item"><img src="/de/sites/default/files/2020-08/scale-green-2_0.svg" alt="" loading="lazy" typeof="foaf:Image" /></div><div class="clearfix text-formatted field field--name-field-html field--type-text-long field--label-hidden field__item"><p class="text-align-center"><strong>Schnelle Anpassung</strong></p><p class="text-align-center">Von kleinen Panels bis zu mehr als 1 Million Sonden pro Pool</p></div></div></div></div></div></div></div><div class="paragraph col--bleed col-lg-3 col-sm-3 col-12 paragraph--type--column paragraph--view-mode--default"><div class="tile column-background text-align-center " style="background-color:transparent; "><div class="field field--name-field-paragraph-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--icon-with-text paragraph--view-mode--default image-top background" style="background-color:transparent"><div class="inner-wrapper text-align-center"><div class="field field--name-field-icon field--type-image field--label-hidden field__item"><img src="/de/sites/default/files/2020-08/coverage-green-2_0.svg" alt="" loading="lazy" typeof="foaf:Image" /></div><div class="clearfix text-formatted field field--name-field-html field--type-text-long field--label-hidden field__item"><p class="text-align-center"><strong>Maximierte Sequenzierungseffizienz und außergewöhnliche Abdeckungsgleichmäßigkeit</strong></p><p class="text-align-center">Verbessern Sie die Abdeckungstiefe oder führen Sie mehr Proben mit demselben Budget aus.</p></div></div></div></div></div></div></div><div class="paragraph col--bleed col-lg-3 col-sm-3 col-12 paragraph--type--column paragraph--view-mode--default"><div class="tile column-background text-align-center " style="background-color:transparent; "><div class="field field--name-field-paragraph-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--icon-with-text paragraph--view-mode--default image-top background" style="background-color:transparent"><div class="inner-wrapper text-align-center"><div class="field field--name-field-icon field--type-image field--label-hidden field__item"><img src="/de/sites/default/files/2020-08/target-green-2_0.svg" alt="" loading="lazy" typeof="foaf:Image" /></div><div class="clearfix text-formatted field field--name-field-html field--type-text-long field--label-hidden field__item"><p class="text-align-center"><strong>Erhöhen Sie das Vertrauen in die Variantenidentifizierung</strong></p><p class="text-align-center">Lassen Sie kein Molekül zurück, erfassen Sie jedes Molekül.</p></div></div></div></div></div></div></div></div></div></div></section></div><div class="field__item"><section class="section-background ngs-content-wrapper" style="background-color:transparent;"><div class="clearfix component-paragraph paragraph paragraph--type--section paragraph--view-mode--default"><div class="section-wrapper container"><div class="row"><div class="paragraph col--bleed col-lg-6 col-sm-12 col-12 paragraph--type--column paragraph--view-mode--default"><div class="tile column-background " style="background-color:transparent; "><div class="field field--name-field-paragraph-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--text paragraph--view-mode--default"><div class="tile " style="background-color: transparent;"><div class="clearfix text-formatted field field--name-field-paragraph-text field--type-text-long field--label-hidden field__item"><div class="verical-align" style="display:none;"><h3>Verbesserte Tiefe bei gleichzeitiger Reduzierung der Gesamtsequenzierung</h3><p class="dark-gray-text size18">Unsere Sonden ermöglichen eine bessere Abdeckung der beabsichtigten Ziele im Vergleich zu den Sonden der Konkurrenz. Die verbesserte Gleichmäßigkeit unseres Panels erhöht den Prozentsatz der Basen, die in der gewünschten Tiefe abgedeckt werden, und reduziert die Menge der Übersequenzierung.</p></div></div></div></div></div></div></div></div><div class="paragraph col--bleed col-lg-6 col-sm-12 col-12 paragraph--type--column paragraph--view-mode--default"><div class="tile column-background " style="background-color:transparent; "><div class="field field--name-field-paragraph-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--image paragraph--view-mode--default"><div class="tile mr0 auto-width block-image" style="background-color: transparent;"><img class="twist-lightbox" src="/de/sites/default/files/2020-08/NGS-CumulativeCoverage_0.svg" alt="NGS-Gesamtabdeckung" title="" width="540" height="466" loading="lazy" data-mfp-src="/sites/default/files/2020-08/NGS-CumulativeCoverage_0.svg"></div></div></div></div></div></div><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--text paragraph--view-mode--default"><div class="tile divider " style="background-color: transparent;"><div class="clearfix text-formatted field field--name-field-paragraph-text field--type-text-long field--label-hidden field__item"><style type="text/css">.vertical-align{display:none;} </style></div></div></div><div class="paragraph col--bleed col-lg-6 col-sm-12 col-12 paragraph--type--column paragraph--view-mode--default"><div class="tile column-background " style="background-color:transparent; "><div class="field field--name-field-paragraph-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--image paragraph--view-mode--default"><div class="tile mr0 auto-width block-image" style="background-color: transparent;"><img class="twist-lightbox" src="/de/sites/default/files/2020-08/NGS-uniformity-2.svg" alt="Verbesserung der Tiefe bei gleichzeitiger Reduzierung der Gesamtsequenzierung" title="" width="540" height="549" loading="lazy" data-mfp-src="/sites/default/files/2020-08/NGS-uniformity-2.svg"></div></div></div></div></div></div><div class="paragraph col--bleed col-lg-6 col-sm-12 col-12 paragraph--type--column paragraph--view-mode--default"><div class="tile column-background " style="background-color:transparent; "><div class="field field--name-field-paragraph-components field--type-entity-reference-revisions field--label-hidden field__items"><div class="field__item"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--text paragraph--view-mode--default"><div class="tile " style="background-color: transparent;"><div class="clearfix text-formatted field field--name-field-paragraph-text field--type-text-long field--label-hidden field__item"><div class="verical-align" style="display:none;"><h3>Höheres Vertrauen in die Variantenidentifizierung</h3><p class="dark-gray-text size18">Gleichmäßigkeit beschreibt die Leseverteilung entlang der Zielregionen des Genoms. Eine gleichmäßige Abdeckung verringert den Sequenzierungsaufwand, der erforderlich ist, um eine ausreichende Abdeckungstiefe für alle Regionen von Interesse zu erreichen. Das Erfüllen der Sequenzierungsanforderungen für Ihre Anwendung bedeutet ein höheres Vertrauen in die Variantenidentifizierung.</p></div></div></div></div></div></div></div></div></div></div></div></section></div><div class="field__item"><section class="section-background" style="background-color:transparent;"><div class="clearfix component-paragraph paragraph paragraph--type--section paragraph--view-mode--default"><div class="section-wrapper container"><div class="row"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--html paragraph--view-mode--default"><div style="background-color:transparent"><div class="clearfix text-formatted field field--name-field-html field--type-text-long field--label-hidden field__item"><h3 class="text-align-center">Mehr über NGS erfahren</h3><p> </p><script src="https://fast.wistia.com/embed/medias/n49pgsc9f6.jsonp" async></script><script src="https://fast.wistia.com/assets/external/E-v1.js" async></script><div class="wistia_responsive_padding" style="padding:56.25% 0 0 0;position:relative;"><div class="wistia_responsive_wrapper" style="height:100%;left:0;position:absolute;top:0;width:100%;"><div class="wistia_embed wistia_async_n49pgsc9f6 videoFoam=true" style="height:100%;position:relative;width:100%"><div class="wistia_swatch" style="height:100%;left:0;opacity:0;overflow:hidden;position:absolute;top:0;transition:opacity 200ms;width:100%;"><img alt aria-hidden="true" onload="this.parentNode.style.opacity=1;" src="https://fast.wistia.com/embed/medias/n49pgsc9f6/swatch" style="filter:blur(5px);height:100%;object-fit:contain;width:100%;"></div></div></div></div></div></div></div></div></div></div></section></div><div class="field__item"><div class="paragraph paragraph--type--component-testimonials paragraph--view-mode--default col-lg-12 col-sm-12 col-12"><h2 class="cp-title">Erfahrungsberichte</h2><div class="testimonials-wrapper-slick clearfix"><div class="sub-block sub-block-0"><span class="testimonial-quote" style="color: #19805E">“</span><div class="ti-quote">Durch flexible und kostengünstige Panels haben wir mehr Proben verarbeiten und somit noch tiefer reichende Analysen durchführen können, um diese Varianten mit sehr, sehr geringen Fraktionen zu erkennen.“ </div><div class="bottom-data"><div class="ti-img"></div><div class="ti-name">Brendan Blumenstiel</div><div class="ti-institution">Broad Institute of MIT and Harvard</div></div></div><div class="sub-block sub-block-1"><span class="testimonial-quote" style="color: #19805E">“</span><div class="ti-quote">Ich hatte gehört, dass die Twist Target Enrichment-Werkzeuge eine unglaubliche Gleichförmigkeit erzielten. Wir beschlossen, das neue Twist Exom auszuprobieren, um uns eine eigene Meinung zu bilden. Es stimmte! Nicht nur die Gleichförmigkeit war unglaublich, sondern auch die Abdeckung. Jetzt verwenden wir ein Twist Custom Panel, das auf die spezifischen Anforderungen unserer Patienten zugeschnitten ist.</div><div class="bottom-data"><div class="ti-img"></div><div class="ti-name">Dr. Simon von Ameln</div><div class="ti-institution">ÜBAG Dres. Habets / Keller / Groschek / Danaei – Aachen, Deutschland</div></div></div><div class="sub-block sub-block-2"><span class="testimonial-quote" style="color: #19805E">“</span><div class="ti-quote">Mit Twist Custom Panels konnten wir uns auf wichtige, medizinisch relevante Gene konzentrieren, anstatt auf das gesamte Genom. Das Panel war prägnant und wies ein einfaches Protokoll und angemessene Kosten bei sehr guten Kandidatenvarianten auf, die bereits in der Literatur kuratiert wurden. </div><div class="bottom-data"><div class="ti-img"></div><div class="ti-name">Renata Pelligrino, PhD.</div><div class="ti-institution">Children’s Hospital of Philadelphia</div></div></div></div></div></div><div class="field__item"><section class="section-background" style="background-color:transparent;"><div class="clearfix component-paragraph paragraph paragraph--type--section paragraph--view-mode--default"><div class="section-wrapper container"><div class="row"><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--html paragraph--view-mode--default"><div style="background-color:transparent"><div class="clearfix text-formatted field field--name-field-html field--type-text-long field--label-hidden field__item"><h2 class="text-align-center">Weitere NGS-Ressourcen</p></h2></div></div></div><div class="paragraph paragraph--type--component-resource-reference paragraph--view-mode--default section-wrapper"><div class="field field--name-field-rr-resource field--type-entity-reference field--label-hidden row field__items"><div class="field__item col-md-4 col-sm-4"><a href="/de/resources/protocol/twist-target-enrichment-standard-hybridization-v1-protocol" data-history-node-id="4461" about="/resources/protocol/twist-target-enrichment-standard-hybridization-v1-protocol" class="resource-card resource--theme-ngs"><h6 class="title"> Twist Target Enrichment Standard Hybridization v1 Protocol </h6><div class="resource-info"><span class="type"><img src="https://www.twistbioscience.com/de/sites/default/files/2020-08/dark-protocol-slate.svg" width="16px" height="16px" /> Protokoll </span><span class="family" style="background:#E6F6F0; color:#105928;">NGS</span></div><div class="subtitle"> Ein umfassendes Protokoll zur Anreicherung genomischer DNA-Libraries mit einer 16-stündigen Hybridisierung in einem zweitägigen Workflow </div></a></div><div class="field__item col-md-4 col-sm-4"><a href="/de/resources/technical-note/utility-twist-respiratory-viral-controls-sars-cov-2-and-multiplexed" data-history-node-id="6031" about="/resources/technical-note/utility-twist-respiratory-viral-controls-sars-cov-2-and-multiplexed" class="resource-card resource--theme-synthetic-controls"><h6 class="title"> Der Nutzen von Twist Respiratory Viral Controls für den Nachweis von SARS-CoV-2 und Multiplex-Pathogen </h6><div class="resource-info"><span class="type"><img src="https://www.twistbioscience.com/de/sites/default/files/2020-08/dark-technote-slate.svg" width="16px" height="16px" /> Technischer Hinweis </span><span class="family" style="background:#E6F6F0; color:#105928;">Synthetische Kontrollen</span></div><div class="subtitle"> Diverse Atemwegsvirus-Kontrollen zur genauen Abgrenzung zwischen Infektionserregern mit überlappenden Symptomen </div></a></div><div class="field__item col-md-4 col-sm-4"><a href="/de/resources/webinar/custom-enrichment-rna-sequencing-liquid-biopsies" data-history-node-id="4451" about="/resources/webinar/custom-enrichment-rna-sequencing-liquid-biopsies" class="resource-card resource--theme-ngs"><h6 class="title"> Custom enrichment for RNA sequencing of liquid biopsies </h6><div class="resource-info"><span class="type"><img src="https://www.twistbioscience.com/de/sites/default/files/2020-08/dark-webinar-slate.svg" width="16px" height="16px" /> Webinar </span><span class="family" style="background:#E6F6F0; color:#105928;">NGS</span></div><div class="subtitle"> Believe in Better: Leading the Way in Target Enrichment </div></a></div></div></div><div class="paragraph col-lg-12 col-sm-12 col-12 paragraph--type--text paragraph--view-mode--default"><div class="tile " style="background-color: transparent;"><div class="clearfix text-formatted field field--name-field-paragraph-text field--type-text-long field--label-hidden field__item"><p class="text-align-center"><a 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