CINXE.COM

<!doctype html> <html lang="en-US"> <head> <script type="text/javascript"> /*(function(){ if (document.cookie.indexOf('vip-go-cb') == -1) return; class CSPErrorUtil { constructor ( run = true, print = false ) { this.options = { run: run, print: print } this.previousState = '' this.errorContainerElement = {} this.initialize() } initialize = () => { if ( ! this.options.run ) return window.cspErrorMessages = {} window.addEventListener( "securitypolicyviolation", this.trackViolationHandler ) if ( ! this.options.print) return window.addEventListener( "DOMContentLoaded", this.buildViolationsContainer ) } trackViolationHandler = (e) => { this.recordState() let directive = e.violatedDirective.replaceAll('-','_') let source = this.parseSource(e.blockedURI) if( ! ( directive in window.cspErrorMessages ) ) window.cspErrorMessages[directive] = [] if( window.cspErrorMessages[directive].indexOf(source) == -1 ) window.cspErrorMessages[directive].push(source) if( this.checkStateIsUpdated() ) this.printViolations() } buildViolationsContainer = () => { let tags = { body: document.querySelector('body'), errorContainerElement: document.createElement('div') } let errorContainerAttributes = { classList: 'errorContainer', id: 'errorContainer', style: 'display: none' } Object.assign(tags.errorContainerElement, errorContainerAttributes) tags.body.append(tags.errorContainerElement) this.errorContainerElement = tags.errorContainerElement } getViolations = () => { return JSON.stringify(window.cspErrorMessages); } printViolations = () => { if( ! this.options.print ) return this.errorContainerElement.textContent = this.getViolations() } recordState = () => { this.previousState = this.getViolations() } checkStateIsUpdated = () => { return this.previousState != this.getViolations() } parseSource = url => { try { let urlObj = new URL(url) return urlObj.protocol + "//" + urlObj.hostname } catch(e) { //window.cspErrorMessages['invalid'] = window.cspErrorMessages['invalid'] || [] //if(!window.cspErrorMessages.invalid.includes('INVALID SRC:' + url)) { // window.cspErrorMessages['invalid'].push('INVALID SRC:' + url) //} return 'INVALID: ' + url } } } window.cspErrorUtil = new CSPErrorUtil(true, true) })()*/ </script> <meta charset="UTF-8"> <meta name="viewport" content="width=device-width, initial-scale=1"> <meta name="google-site-verification" content="cz45B7JVyQN-nDhh3OX4aAd0ltemit0E7Woivwl37s8" /> <link rel="profile" href="https://gmpg.org/xfn/11"> <meta name='robots' content='index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1' /> <style>img:is([sizes="auto" i], [sizes^="auto," i]) { contain-intrinsic-size: 3000px 1500px }</style> <title>2023 Annual Letter - Chan Zuckerberg Initiative</title> <meta name="description" content="Read CZI's 2023 annual letter to find out how we have been leveraging and advancing technology to accelerate our impact across science and education." /> <link rel="canonical" href="https://chanzuckerberg.com/about/annual-letter/year-2023/" /> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="article" /> <meta property="og:title" content="CZI Annual Letter 2023: Building for This Moment" /> <meta property="og:description" content="We’re accelerating scientific discovery with AI. Read how we got here and where we’re headed" /> <meta property="og:url" content="https://chanzuckerberg.com/about/annual-letter/year-2023/" /> <meta property="og:site_name" content="Chan Zuckerberg Initiative" /> <meta property="article:publisher" content="https://www.facebook.com/chanzuckerberginitiative/" /> <meta property="article:modified_time" content="2023-12-05T14:20:52+00:00" /> <meta property="og:image" content="https://chanzuckerberg.com/wp-content/uploads/2023/12/Mark-Zuckerberg-and-Priscilla-Chan-by-Cody-Pickens-The-Forbes-Collection_0088.jpg" /> <meta property="og:image:width" content="2000" /> <meta property="og:image:height" content="1334" /> <meta property="og:image:type" content="image/jpeg" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:title" content="CZI Annual Letter 2023: Building for This Moment" /> <meta name="twitter:description" content="We’re accelerating scientific discovery with AI. Read how we got here and where we’re headed" /> <meta name="twitter:image" content="https://chanzuckerberg.com/wp-content/uploads/2023/12/Mark-Zuckerberg-and-Priscilla-Chan-by-Cody-Pickens-The-Forbes-Collection_0088.jpg" /> <meta name="twitter:site" content="@ChanZuckerberg" /> <script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"WebPage","@id":"https://chanzuckerberg.com/about/annual-letter/year-2023/","url":"https://chanzuckerberg.com/about/annual-letter/year-2023/","name":"2023 Annual Letter - Chan Zuckerberg Initiative","isPartOf":{"@id":"https://chanzuckerberg.com/#website"},"datePublished":"2023-12-04T19:16:16+00:00","dateModified":"2023-12-05T14:20:52+00:00","description":"Read CZI's 2023 annual letter to find out how we have been leveraging and advancing technology to accelerate our impact across science and education.","breadcrumb":{"@id":"https://chanzuckerberg.com/about/annual-letter/year-2023/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https://chanzuckerberg.com/about/annual-letter/year-2023/"]}]},{"@type":"BreadcrumbList","@id":"https://chanzuckerberg.com/about/annual-letter/year-2023/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://chanzuckerberg.com/"},{"@type":"ListItem","position":2,"name":"About*","item":"https://chanzuckerberg.com/about/"},{"@type":"ListItem","position":3,"name":"Annual Letters","item":"https://chanzuckerberg.com/about/annual-letter/"},{"@type":"ListItem","position":4,"name":"Annual Letter 2023"}]},{"@type":"WebSite","@id":"https://chanzuckerberg.com/#website","url":"https://chanzuckerberg.com/","name":"Chan Zuckerberg Initiative","description":"A future for everyone","publisher":{"@id":"https://chanzuckerberg.com/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://chanzuckerberg.com/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https://chanzuckerberg.com/#organization","name":"Chan Zuckerberg Initiative","alternateName":"CZI","url":"https://chanzuckerberg.com/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https://chanzuckerberg.com/#/schema/logo/image/","url":"https://chanzuckerberg.com/wp-content/uploads/2018/12/czi-social-sharing-logo-1200-630-2.png","contentUrl":"https://chanzuckerberg.com/wp-content/uploads/2018/12/czi-social-sharing-logo-1200-630-2.png","width":1200,"height":630,"caption":"Chan Zuckerberg Initiative"},"image":{"@id":"https://chanzuckerberg.com/#/schema/logo/image/"},"sameAs":["https://www.facebook.com/chanzuckerberginitiative/","https://x.com/ChanZuckerberg","https://www.instagram.com/chanzuckerberginitiative/","https://www.linkedin.com/company/chan-zuckerberg-initiative/","https://www.youtube.com/channel/UCZioJ6fb9SuRdLIO7DlE09w"]}]}</script> <link rel='dns-prefetch' href='//fast.wistia.com' /> <link rel='dns-prefetch' href='//cdn.split.io' /> <link rel='dns-prefetch' href='//stats.wp.com' /> <link rel='dns-prefetch' href='//use.typekit.net' /> <link rel='dns-prefetch' href='//v0.wordpress.com' /> <link rel="alternate" type="application/rss+xml" title="Chan Zuckerberg Initiative » Feed" href="https://chanzuckerberg.com/feed/" /> <link rel='stylesheet' id='all-css-0' href='https://chanzuckerberg.com/_static/??-eJzTLy/QTc7PK0nNK9EvyUjNTS3WT67K1E8DChXrO+ZmFmXqF5dU5qQWZ6SmluglFxfr6OPT4eGt616UX5JanE2SNqfEopz8ciK1gFWBFNjn2hqaGxuZmZmam5gBAPnfSlQ=' type='text/css' media='all' /> <link rel='stylesheet' id='chan-zuckerberg-titling-gothic-fb-css' href='https://use.typekit.net/klq6bqd.css?ver=6.7.1' media='all' /> <link rel='stylesheet' id='all-css-2' href='https://chanzuckerberg.com/_static/??-eJx9jUsOwjAMBS+E6xIkWCHOko8pVhMnilOh3h6jii3b0bx5+G4QqwySgS1vC4uiIeXSMkGodWVZIPpMknyH1qnwVtCr0lCMqqhjN/PZLQImTYVlMn76Zlhi3hIdYvL6YvvSPwrrwJBrXCFz6L7vR/63eJT7+XZxbr7Ozn0AEDdE3Q==' type='text/css' media='all' /> <link rel='stylesheet' id='all-css-4' href='https://chanzuckerberg.com/_static/??-eJzTLy/QzcxLzilNSS3WzyrWz01NyUxMzUnNTc0rQeEU5CRWphbp5qSmJyZX6uVm5uklFxfr6OPTDpRD5sM02efaGpobGxkZmBkYGQMARIMu1Q==' type='text/css' media='all' /> <style id='jetpack-sharing-buttons-style-inline-css'> .jetpack-sharing-buttons__services-list{display:flex;flex-direction:row;flex-wrap:wrap;gap:0;list-style-type:none;margin:5px;padding:0}.jetpack-sharing-buttons__services-list.has-small-icon-size{font-size:12px}.jetpack-sharing-buttons__services-list.has-normal-icon-size{font-size:16px}.jetpack-sharing-buttons__services-list.has-large-icon-size{font-size:24px}.jetpack-sharing-buttons__services-list.has-huge-icon-size{font-size:36px}@media print{.jetpack-sharing-buttons__services-list{display:none!important}}.editor-styles-wrapper .wp-block-jetpack-sharing-buttons{gap:0;padding-inline-start:0}ul.jetpack-sharing-buttons__services-list.has-background{padding:1.25em 2.375em} </style> <style id='elasticpress-facet-style-inline-css'> .widget_ep-facet input[type=search],.wp-block-elasticpress-facet input[type=search]{margin-bottom:1rem}.widget_ep-facet .searchable .inner,.wp-block-elasticpress-facet .searchable .inner{max-height:20em;overflow:scroll}.widget_ep-facet .term.hide,.wp-block-elasticpress-facet .term.hide{display:none}.widget_ep-facet .empty-term,.wp-block-elasticpress-facet .empty-term{opacity:.5;position:relative}.widget_ep-facet .empty-term:after,.wp-block-elasticpress-facet .empty-term:after{bottom:0;content:" ";display:block;left:0;position:absolute;right:0;top:0;width:100%;z-index:2}.widget_ep-facet .level-1,.wp-block-elasticpress-facet .level-1{padding-left:20px}.widget_ep-facet .level-2,.wp-block-elasticpress-facet .level-2{padding-left:40px}.widget_ep-facet .level-3,.wp-block-elasticpress-facet .level-3{padding-left:60px}.widget_ep-facet .level-4,.wp-block-elasticpress-facet .level-4{padding-left:5pc}.widget_ep-facet .level-5,.wp-block-elasticpress-facet .level-5{padding-left:75pt}.widget_ep-facet input[disabled],.wp-block-elasticpress-facet input[disabled]{cursor:pointer;opacity:1}.widget_ep-facet .term a,.wp-block-elasticpress-facet .term a{-webkit-box-align:center;-ms-flex-align:center;align-items:center;display:-webkit-box;display:-ms-flexbox;display:flex;position:relative}.widget_ep-facet .term a:hover .ep-checkbox,.wp-block-elasticpress-facet .term a:hover .ep-checkbox{background-color:#ccc}.ep-checkbox{-webkit-box-align:center;-ms-flex-align:center;-ms-flex-negative:0;-webkit-box-pack:center;-ms-flex-pack:center;align-items:center;background-color:#eee;display:-webkit-box;display:-ms-flexbox;display:flex;flex-shrink:0;height:1em;justify-content:center;margin-right:.25em;width:1em}.ep-checkbox:after{border:solid #fff;border-width:0 .125em .125em 0;content:"";display:none;height:.5em;-webkit-transform:rotate(45deg);transform:rotate(45deg);width:.25em}.ep-checkbox.checked{background-color:#5e5e5e}.ep-checkbox.checked:after{display:block} </style> <link rel='stylesheet' id='all-css-8' href='https://chanzuckerberg.com/wp-content/mu-plugins/search/elasticpress/dist/css/related-posts-block-styles.min.css?m=1730999764g' type='text/css' media='all' /> <style id='classic-theme-styles-inline-css'> /*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} </style> <style id='global-styles-inline-css'> :root{--wp--preset--aspect-ratio--square: 1;--wp--preset--aspect-ratio--4-3: 4/3;--wp--preset--aspect-ratio--3-4: 3/4;--wp--preset--aspect-ratio--3-2: 3/2;--wp--preset--aspect-ratio--2-3: 2/3;--wp--preset--aspect-ratio--16-9: 16/9;--wp--preset--aspect-ratio--9-16: 9/16;--wp--preset--color--black: #000000;--wp--preset--color--cyan-bluish-gray: #abb8c3;--wp--preset--color--white: #ffffff;--wp--preset--color--pale-pink: #f78da7;--wp--preset--color--vivid-red: #cf2e2e;--wp--preset--color--luminous-vivid-orange: #ff6900;--wp--preset--color--luminous-vivid-amber: #fcb900;--wp--preset--color--light-green-cyan: #7bdcb5;--wp--preset--color--vivid-green-cyan: #00d084;--wp--preset--color--pale-cyan-blue: #8ed1fc;--wp--preset--color--vivid-cyan-blue: #0693e3;--wp--preset--color--vivid-purple: #9b51e0;--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple: linear-gradient(135deg,rgba(6,147,227,1) 0%,rgb(155,81,224) 100%);--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan: linear-gradient(135deg,rgb(122,220,180) 0%,rgb(0,208,130) 100%);--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange: linear-gradient(135deg,rgba(252,185,0,1) 0%,rgba(255,105,0,1) 100%);--wp--preset--gradient--luminous-vivid-orange-to-vivid-red: linear-gradient(135deg,rgba(255,105,0,1) 0%,rgb(207,46,46) 100%);--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray: linear-gradient(135deg,rgb(238,238,238) 0%,rgb(169,184,195) 100%);--wp--preset--gradient--cool-to-warm-spectrum: linear-gradient(135deg,rgb(74,234,220) 0%,rgb(151,120,209) 20%,rgb(207,42,186) 40%,rgb(238,44,130) 60%,rgb(251,105,98) 80%,rgb(254,248,76) 100%);--wp--preset--gradient--blush-light-purple: linear-gradient(135deg,rgb(255,206,236) 0%,rgb(152,150,240) 100%);--wp--preset--gradient--blush-bordeaux: linear-gradient(135deg,rgb(254,205,165) 0%,rgb(254,45,45) 50%,rgb(107,0,62) 100%);--wp--preset--gradient--luminous-dusk: linear-gradient(135deg,rgb(255,203,112) 0%,rgb(199,81,192) 50%,rgb(65,88,208) 100%);--wp--preset--gradient--pale-ocean: linear-gradient(135deg,rgb(255,245,203) 0%,rgb(182,227,212) 50%,rgb(51,167,181) 100%);--wp--preset--gradient--electric-grass: linear-gradient(135deg,rgb(202,248,128) 0%,rgb(113,206,126) 100%);--wp--preset--gradient--midnight: linear-gradient(135deg,rgb(2,3,129) 0%,rgb(40,116,252) 100%);--wp--preset--font-size--small: 13px;--wp--preset--font-size--medium: 20px;--wp--preset--font-size--large: 36px;--wp--preset--font-size--x-large: 42px;--wp--preset--spacing--20: 0.44rem;--wp--preset--spacing--30: 0.67rem;--wp--preset--spacing--40: 1rem;--wp--preset--spacing--50: 1.5rem;--wp--preset--spacing--60: 2.25rem;--wp--preset--spacing--70: 3.38rem;--wp--preset--spacing--80: 5.06rem;--wp--preset--shadow--natural: 6px 6px 9px rgba(0, 0, 0, 0.2);--wp--preset--shadow--deep: 12px 12px 50px rgba(0, 0, 0, 0.4);--wp--preset--shadow--sharp: 6px 6px 0px rgba(0, 0, 0, 0.2);--wp--preset--shadow--outlined: 6px 6px 0px -3px rgba(255, 255, 255, 1), 6px 6px rgba(0, 0, 0, 1);--wp--preset--shadow--crisp: 6px 6px 0px rgba(0, 0, 0, 1);}:where(.is-layout-flex){gap: 0.5em;}:where(.is-layout-grid){gap: 0.5em;}body .is-layout-flex{display: flex;}.is-layout-flex{flex-wrap: wrap;align-items: center;}.is-layout-flex > :is(*, div){margin: 0;}body .is-layout-grid{display: grid;}.is-layout-grid > :is(*, div){margin: 0;}:where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;}:where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;}.has-black-color{color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-color{color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-color{color: var(--wp--preset--color--white) !important;}.has-pale-pink-color{color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-color{color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-color{color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-color{color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-color{color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-color{color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-color{color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-color{color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-color{color: var(--wp--preset--color--vivid-purple) !important;}.has-black-background-color{background-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-background-color{background-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-background-color{background-color: var(--wp--preset--color--white) !important;}.has-pale-pink-background-color{background-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-background-color{background-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-background-color{background-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-background-color{background-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-background-color{background-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-background-color{background-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-background-color{background-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-background-color{background-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-background-color{background-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-border-color{border-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-border-color{border-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-border-color{border-color: var(--wp--preset--color--white) !important;}.has-pale-pink-border-color{border-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-border-color{border-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-border-color{border-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-border-color{border-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-border-color{border-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-border-color{border-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-border-color{border-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-border-color{border-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-border-color{border-color: var(--wp--preset--color--vivid-purple) !important;}.has-vivid-cyan-blue-to-vivid-purple-gradient-background{background: var(--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple) !important;}.has-light-green-cyan-to-vivid-green-cyan-gradient-background{background: var(--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan) !important;}.has-luminous-vivid-amber-to-luminous-vivid-orange-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange) !important;}.has-luminous-vivid-orange-to-vivid-red-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-orange-to-vivid-red) !important;}.has-very-light-gray-to-cyan-bluish-gray-gradient-background{background: var(--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray) !important;}.has-cool-to-warm-spectrum-gradient-background{background: var(--wp--preset--gradient--cool-to-warm-spectrum) !important;}.has-blush-light-purple-gradient-background{background: var(--wp--preset--gradient--blush-light-purple) !important;}.has-blush-bordeaux-gradient-background{background: var(--wp--preset--gradient--blush-bordeaux) !important;}.has-luminous-dusk-gradient-background{background: var(--wp--preset--gradient--luminous-dusk) !important;}.has-pale-ocean-gradient-background{background: var(--wp--preset--gradient--pale-ocean) !important;}.has-electric-grass-gradient-background{background: var(--wp--preset--gradient--electric-grass) !important;}.has-midnight-gradient-background{background: var(--wp--preset--gradient--midnight) !important;}.has-small-font-size{font-size: var(--wp--preset--font-size--small) !important;}.has-medium-font-size{font-size: var(--wp--preset--font-size--medium) !important;}.has-large-font-size{font-size: var(--wp--preset--font-size--large) !important;}.has-x-large-font-size{font-size: var(--wp--preset--font-size--x-large) !important;} :where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;} :where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;} :root :where(.wp-block-pullquote){font-size: 1.5em;line-height: 1.6;} </style> <script type="text/javascript" src="https://chanzuckerberg.com/_static/??-eJzTLy/QzcxLzilNSS3WzwKiwtLUokoopZebmaeXVayjj0+Rbm5melFiSSpUsX2uraG5sZGRgZmBkXEWAK8tIhI=" ></script><link rel='shortlink' href='https://wp.me/PamUkM-7N1' /> <style type="text/css"></style> <style>img#wpstats{display:none}</style> <script> function loadHbspt() { let event = new Event('hubspotLoaded'); window.dispatchEvent(event); } </script> <script charset="utf-8" type="text/javascript" defer src="//js.hsforms.net/forms/v2.js" onload="loadHbspt()"></script> <meta name="facebook-domain-verification" content="mziamrj37acb4rk2r1q5rrsvcuwri5" /><link rel="icon" href="https://chanzuckerberg.com/wp-content/uploads/2018/04/new-logo.png?w=32" sizes="32x32" /> <link rel="icon" href="https://chanzuckerberg.com/wp-content/uploads/2018/04/new-logo.png?w=108" sizes="192x192" /> <link rel="apple-touch-icon" href="https://chanzuckerberg.com/wp-content/uploads/2018/04/new-logo.png?w=108" /> <meta name="msapplication-TileImage" content="https://chanzuckerberg.com/wp-content/uploads/2018/04/new-logo.png?w=108" /> </head> <body class="page-template page-template-templates page-template-about-annual-letter-2023 page-template-templatesabout-annual-letter-2023-php page page-id-29947 page-child parent-pageid-28576 header-static page-year-2023"> <div id="breakpoints"></div> <div id="page" class="site"> <header class="header header--light"> <div class="header__top-nav"> <div class="header__grouping"> <div class="header__logo"> <a href="https://chanzuckerberg.com" title="New Homepage"> <img class="header__logo__image desktop-only" src="https://chanzuckerberg.com/wp-content/themes/czi/img/logo.svg" alt="Chan Zuckerberg Initiative logo"> <img class="header__logo__image mobile-only" src="https://chanzuckerberg.com/wp-content/themes/czi/img/logo.svg" alt="Chan Zuckerberg Initiative logo"> <img class="header__logo__image header__logo__image--alt" src="https://chanzuckerberg.com/wp-content/themes/czi/img/logo-dark.svg" alt="Chan Zuckerberg Initiative logo"> <img class="header__logo__image-minified" src="https://chanzuckerberg.com/wp-content/themes/czi/img/logo-minified.svg" alt="Chan Zuckerberg Initiative logo"> </a> </div> <nav class="header__nav" aria-label="Main Navigation"> <ul class="header__nav-list"> <li class="t-nav"> <a target="" href="https://chanzuckerberg.com/about/our-approach/" class="header--uppercase header--bold header__text page-item"> About Us </a> <div class="sub-menu"> <div class="sub-menu__wrapper"> <div class="sub-menu__col"> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/about/our-approach/">Our Approach</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/about/leaders/">Our Leadership</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/about/annual-letter/">Annual Letters</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/about/investing-our-endowment/">Investing Our Endowment</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/ethics-policies/">Ethics Policies & Guidelines</a> </li> </ul> </div> </div> </div> </li> <li class="t-nav"> <a target="" href="https://chanzuckerberg.com/about/our-approach/#four-column" class="header--uppercase header--bold header__text page-item"> What We Do </a> <div class="sub-menu"> <div class="sub-menu__wrapper"> <div class="sub-menu__col"> <a href="https://chanzuckerberg.com/science/" class="header--big header--bold">Science</a> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/science/">Overview</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/science/our-values-approach/">Our Values & Approach</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/science/programs-resources/">Programs</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/science/institutes/">Institutes</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/science/technology/">Technology</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/science/meetings/">Meetings</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/science/science-funding/">Funding</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/science/research/">Research</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/science/team/">Science Team</a> </li> </ul> </div> <div class="sub-menu__col"> <a href="https://chanzuckerberg.com/education/" class="header--big header--bold">Education</a> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/education/">Overview</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/education/whole-child-approach-to-education/">Whole Child Approach</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/education/impact/">Impact</a> </li> <li> <a class="page-item" href="https://tech.chanzuckerberg.com/edtech/">Technology</a> </li> </ul> </div> <div class="sub-menu__col"> <a href="https://chanzuckerberg.com/community/" class="header--big header--bold">Community</a> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/community/">Overview</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/community/housing-affordability/">Housing Affordability</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/community/economic-inclusion/">Economic Inclusion</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/community/san-mateo-county/">San Mateo County Partnerships</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/communityspace/">Community Space</a> </li> </ul> </div> </div> </div> </li> <li class="t-nav"> <a target="" href="https://chanzuckerberg.com/about/our-approach/#our-approach" class="header--uppercase header--bold header__text page-item"> How We Work </a> <div class="sub-menu"> <div class="sub-menu__wrapper"> <div class="sub-menu__col"> <a href="https://tech.chanzuckerberg.com/" class="header--big header--bold">Technology</a> <ul> <li> <a class="page-item" href="https://tech.chanzuckerberg.com/">Overview</a> </li> <li> <a class="page-item" href="https://tech.chanzuckerberg.com/scitech/">Science</a> </li> <li> <a class="page-item" href="https://tech.chanzuckerberg.com/edtech/">Education</a> </li> <li> <a class="page-item" href="https://tech.chanzuckerberg.com/careers/">Tech Careers</a> </li> </ul> </div> <div class="sub-menu__col"> <a href="https://chanzuckerberg.com/grants-ventures/" class="header--big header--bold">Grants & <span>Ventures</span></a> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/grants-ventures/">Overview</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/grants-ventures/grants/">Grants</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/grants-ventures/ventures/">Ventures</a> </li> </ul> </div> <div class="sub-menu__col"> <a href="https://chanzuckerberg.com/dei/" class="header--big header--bold">Diversity, Equity, <span>Inclusion & Accessibility</span></a> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/dei/">Overview</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/dei/workplace/">DEIA at CZI</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/dei/racial-equity-funding/">Racial Equity Funding</a> </li> </ul> </div> <div class="sub-menu__col"> <a href="https://chanzuckerberg.com/capacity-building/" class="header--big header--bold">Capabilities & Resources</a> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/capacity-building/">Capacity Building</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/capacity-building/training-sessions/">Training Sessions</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/public-opinion-survey-science/">Public Opinion & Survey Science</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/resources/">Resources</a> </li> </ul> </div> </div> </div> </li> <li class="t-nav"> <a target="" href="https://chanzuckerberg.com/newsroom/" class="header--uppercase header--bold header__text page-item"> News & Stories </a> <div class="sub-menu"> <div class="sub-menu__wrapper"> <div class="sub-menu__col"> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/newsroom/">Newsroom</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/blog/">Stories</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/videos/">Videos</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/newsroom/media-gallery/">Media Gallery</a> </li> </ul> </div> </div> </div> </li> <li class="t-nav"> <a target="" href="https://chanzuckerberg.com/careers/" class="header--uppercase header--bold header__text page-item"> Careers </a> <div class="sub-menu"> <div class="sub-menu__wrapper"> <div class="sub-menu__col"> <ul> <li> <a class="page-item" href="https://chanzuckerberg.com/careers/">Why CZI?</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/careers/career-opportunities/">Explore Roles</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/careers/candidate-journey/">Candidate Journey</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/careers/working-reimagined/">Working ReImagined</a> </li> <li> <a class="page-item" href="https://chanzuckerberg.com/careers/internship-program/">Internship Program</a> </li> </ul> </div> </div> </div> </li> </ul> </nav> <div class="header__actions"> <div class="search-li"> <a id="select-search" href="#" aria-label="Search button" class="select-search--bold"><svg class=" search-icon--black" xmlns="http://www.w3.org/2000/svg" width="23" height="23" viewBox="0 0 23 23" fill="none" alt="Search icon"><path d="M15.5 15.7L21.4 21.6" class="a"/><path d="M9.7 18.1C14.2 18.1 17.9 14.4 17.9 9.9 17.9 5.3 14.2 1.6 9.7 1.6 5.1 1.6 1.4 5.3 1.4 9.9 1.4 14.4 5.1 18.1 9.7 18.1Z" class="a"/></svg></a> </div> <div class="header__cta"> <a href="https://chanzuckerberg.com/blog/" id="header-cta">Read Our Blog</a> </div> <button class="header__burger-toggler"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/burger-open.svg" alt="Burger Toggler"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/burger-close.svg" alt="Burger Close"> </button> </div> </div> </div> <div class="mobile-nav"> <nav> <ul> <li class="t-h4--semibold mobile-nav__item mobile-nav__item--with-subnav color--black">About Us</li> <li class="mobile-nav__subnav"> <ul class="second-level"> <li class="mobile-nav__item"> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/about/our-approach/">Our Approach</a> </li> <li> <a href="https://chanzuckerberg.com/about/leaders/">Our Leadership</a> </li> <li> <a href="https://chanzuckerberg.com/about/annual-letter/">Annual Letters</a> </li> <li> <a href="https://chanzuckerberg.com/about/investing-our-endowment/">Investing Our Endowment</a> </li> <li> <a href="https://chanzuckerberg.com/ethics-policies/">Ethics Policies & Guidelines</a> </li> </ul> </li> </ul> </li> <li class="t-h4--semibold mobile-nav__item mobile-nav__item--with-subnav color--black">What We Do</li> <li class="mobile-nav__subnav"> <ul class="second-level"> <li class="mobile-nav__item"> <a href="https://chanzuckerberg.com/science/" class="t-h6--semibold">Science</a> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/science/">Overview</a> </li> <li> <a href="https://chanzuckerberg.com/science/our-values-approach/">Our Values & Approach</a> </li> <li> <a href="https://chanzuckerberg.com/science/programs-resources/">Programs</a> <ul class="fourth-level"> <li> <a href="https://chanzuckerberg.com/science/programs-resources/cell-science/">Cell Science</a> </li> <li> <a href="https://chanzuckerberg.com/science/programs-resources/imaging/">Imaging</a> </li> <li> <a href="https://chanzuckerberg.com/science/programs-resources/neuroscience/">Neuroscience</a> </li> <li> <a href="https://chanzuckerberg.com/science/programs-resources/open-science/">Open Science</a> </li> <li> <a href="https://chanzuckerberg.com/science/programs-resources/science-society/">Science in Society</a> </li> </ul> </li> <li> <a href="https://chanzuckerberg.com/science/institutes/">Institutes</a> </li> <li> <a href="https://chanzuckerberg.com/science/technology/">Technology</a> <ul class="fourth-level"> <li> <a href="https://chanzuckerberg.com/science/technology/virtual-cells/">Virtual Cells</a> </li> <li> <a href="https://tech.chanzuckerberg.com/scitech/">Tools</a> </li> </ul> </li> <li> <a href="https://chanzuckerberg.com/science/meetings/">Meetings</a> </li> <li> <a href="https://chanzuckerberg.com/science/science-funding/">Funding</a> </li> <li> <a href="https://chanzuckerberg.com/science/research/">Research</a> </li> <li> <a href="https://chanzuckerberg.com/science/team/">Science Team</a> </li> </ul> </li> <li class="mobile-nav__item"> <a href="https://chanzuckerberg.com/education/" class="t-h6--semibold">Education</a> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/education/">Overview</a> </li> <li> <a href="https://chanzuckerberg.com/education/whole-child-approach-to-education/">Whole Child Approach</a> </li> <li> <a href="https://chanzuckerberg.com/education/impact/">Impact</a> </li> <li> <a href="https://tech.chanzuckerberg.com/edtech/">Technology</a> </li> </ul> </li> <li class="mobile-nav__item"> <a href="https://chanzuckerberg.com/community/" class="t-h6--semibold">Community</a> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/community/">Overview</a> </li> <li> <a href="https://chanzuckerberg.com/community/housing-affordability/">Housing Affordability</a> </li> <li> <a href="https://chanzuckerberg.com/community/economic-inclusion/">Economic Inclusion</a> </li> <li> <a href="https://chanzuckerberg.com/community/san-mateo-county/">San Mateo County Partnerships</a> </li> <li> <a href="https://chanzuckerberg.com/communityspace/">Community Space</a> </li> </ul> </li> </ul> </li> <li class="t-h4--semibold mobile-nav__item mobile-nav__item--with-subnav color--black">How We Work</li> <li class="mobile-nav__subnav"> <ul class="second-level"> <li class="mobile-nav__item"> <a href="https://tech.chanzuckerberg.com/" class="t-h6--semibold">Technology</a> <ul class="third-level"> <li> <a href="https://tech.chanzuckerberg.com/">Overview</a> </li> <li> <a href="https://tech.chanzuckerberg.com/scitech/">Science</a> </li> <li> <a href="https://tech.chanzuckerberg.com/edtech/">Education</a> </li> <li> <a href="https://tech.chanzuckerberg.com/careers/">Tech Careers</a> </li> </ul> </li> <li class="mobile-nav__item"> <a href="https://chanzuckerberg.com/grants-ventures/" class="t-h6--semibold">Grants & <span>Ventures</span></a> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/grants-ventures/">Overview</a> </li> <li> <a href="https://chanzuckerberg.com/grants-ventures/grants/">Grants</a> </li> <li> <a href="https://chanzuckerberg.com/grants-ventures/ventures/">Ventures</a> </li> </ul> </li> <li class="mobile-nav__item"> <a href="https://chanzuckerberg.com/dei/" class="t-h6--semibold">Diversity, Equity, <span>Inclusion & Accessibility</span></a> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/dei/">Overview</a> </li> <li> <a href="https://chanzuckerberg.com/dei/workplace/">DEIA at CZI</a> </li> <li> <a href="https://chanzuckerberg.com/dei/racial-equity-funding/">Racial Equity Funding</a> </li> </ul> </li> <li class="mobile-nav__item"> <a href="https://chanzuckerberg.com/capacity-building/" class="t-h6--semibold">Capabilities & Resources</a> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/capacity-building/">Capacity Building</a> </li> <li> <a href="https://chanzuckerberg.com/capacity-building/training-sessions/">Training Sessions</a> </li> <li> <a href="https://chanzuckerberg.com/public-opinion-survey-science/">Public Opinion & Survey Science</a> </li> <li> <a href="https://chanzuckerberg.com/resources/">Resources</a> </li> </ul> </li> </ul> </li> <li class="t-h4--semibold mobile-nav__item mobile-nav__item--with-subnav color--black">News & Stories</li> <li class="mobile-nav__subnav"> <ul class="second-level"> <li class="mobile-nav__item"> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/newsroom/">Newsroom</a> </li> <li> <a href="https://chanzuckerberg.com/blog/">Stories</a> </li> <li> <a href="https://chanzuckerberg.com/videos/">Videos</a> </li> <li> <a href="https://chanzuckerberg.com/newsroom/media-gallery/">Media Gallery</a> </li> </ul> </li> </ul> </li> <li class="t-h4--semibold mobile-nav__item mobile-nav__item--with-subnav color--black">Careers</li> <li class="mobile-nav__subnav"> <ul class="second-level"> <li class="mobile-nav__item"> <ul class="third-level"> <li> <a href="https://chanzuckerberg.com/careers/">Why CZI?</a> </li> <li> <a href="https://chanzuckerberg.com/careers/career-opportunities/">Explore Roles</a> </li> <li> <a href="https://chanzuckerberg.com/careers/candidate-journey/">Candidate Journey</a> </li> <li> <a href="https://chanzuckerberg.com/careers/working-reimagined/">Working ReImagined</a> </li> <li> <a href="https://chanzuckerberg.com/careers/internship-program/">Internship Program</a> </li> </ul> </li> </ul> </li> <li class="t-h4--semibold mobile-nav__item"> <a id="select-search--mobile" class="select-search--bold" href="#"><svg class="search-icon--black" xmlns="http://www.w3.org/2000/svg" width="23" height="23" viewBox="0 0 23 23" fill="none"><path d="M15.5 15.7L21.4 21.6" class="a"></path><path d="M9.7 18.1C14.2 18.1 17.9 14.4 17.9 9.9 17.9 5.3 14.2 1.6 9.7 1.6 5.1 1.6 1.4 5.3 1.4 9.9 1.4 14.4 5.1 18.1 9.7 18.1Z" class="a"></path></svg> Search </a> </li> <li class="mobile-nav__item"> <div class="header__cta"> <a href="https://chanzuckerberg.com/blog/" id="header-cta">Read Our Blog</a> </div> </li> </ul> </nav> </div> <nav class="subnav section--border-bottom desktop-only"> <ul class="subnav__nav"> <li class="subnav__item "> <a target="" href="https://chanzuckerberg.com/about/our-approach/">Our Approach</a> </li> <li class="subnav__item "> <a target="" href="https://chanzuckerberg.com/about/leaders/">Our Leadership</a> </li> <li class="subnav__item "> <a target="" href="https://chanzuckerberg.com/about/annual-letter/">Annual Letters</a> </li> </ul> </nav>  <nav class="subnav--mobile mobile-only"> <ul class="subnav__nav--mobile"> <li class="subnav__item "> <a target="" href="https://chanzuckerberg.com/about/our-approach/">Our Approach</a> </li> <li class="subnav__item "> <a target="" href="https://chanzuckerberg.com/about/leaders/">Our Leadership</a> </li> <li class="subnav__item "> <a target="" href="https://chanzuckerberg.com/about/annual-letter/">Annual Letters</a> </li> </ul> </nav> <div class="page-template-global-search header--global-search-box "> <div class="container--global-search"> <div class="container--search-items"> <form class="search" method="get" action="https://chanzuckerberg.com" role="search" > <div class="search-icon"> <svg xmlns="http://www.w3.org/2000/svg" width="23" height="23" viewBox="0 0 23 23" fill="none" > <style> .c { stroke-width: 2; stroke: #ff414b; } </style> <path d="M15.5 15.7L21.4 21.6" class="c" /> <path d="M9.7 18.1C14.2 18.1 17.9 14.4 17.9 9.9 17.9 5.3 14.2 1.6 9.7 1.6 5.1 1.6 1.4 5.3 1.4 9.9 1.4 14.4 5.1 18.1 9.7 18.1Z" class="c" /> </svg> </div> <input class="search--textfield" type="text" name="s" id="search" value="" placeholder="Search" aria-label="Search" /> <button type="submit"> <div class="button-cta__arrow cta-arrow cta-arrow--red "> <div class="cta-arrow__bkg"></div> </div> </button> </form> <div class="close-icon"> <svg xmlns="http://www.w3.org/2000/svg" width="44" height="44" viewBox="0 0 44 44" fill="none" > <style> .b { stroke-width: 2; stroke: black; } </style> <circle cx="22" cy="22" r="22" fill="#FAFAFA" /> <g opacity="0.8"> <path d="M15.1 14.9L29.2 29.1" class="b" /> <path d="M15.1 29.1L29.2 14.9" class="b" /> </g> </svg> </div> </div> </div> </div> </header> <main id="content" role="main" class="content-wrapper with-subnav ">  <div class="search-overlay "></div> <div class="dimmed-overlay"></div> <div class="global-newsletter newsletter-container newsletter-container--active"> <img class="newsletter-container__close-icon" src="https://chanzuckerberg.com/wp-content/themes/czi/img/close-icon-transparent.svg" alt="Icon of a small black "x" in a light gray circle." close-icon> <div class="newsletter-container__top"> <p id="cta-text">Sign Up For Updates</p> <span id="toggle-button" class="newsletter-container__toggle"><svg width="12" height="6" fill="none" xmlns="http://www.w3.org/2000/svg"><path d="M10.804 5.14L6.098 1.18M1.196 5.32l4.706-3.96" stroke="#000000" stroke-linecap="round"/></svg></span> </div> </div> <div class="newsletter-background" newsletter-overlay></div> <div class="global-newsletter__form" newsletter-form> <div class="global-newsletter__form-container"> <div class="global-newsletter__form-close-icon" close-newsletter-icon> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/close-circle.svg" alt="Icon of a small black "x" in a light gray circle."> </div> <p id="hubspot-global-signup"><em>Sorry, marketing cookies are required to view this form.</em></p> <script> window.addEventListener('hubspotLoaded', () => { hbspt.forms.create({ portalId: "7272273", formId: "e9113fff-53ed-4f0e-a011-73985e78abfc", onFormReady: function(form, ctx){ const event = new CustomEvent('HUBSPOT_LOADED', { detail: form, }) window.dispatchEvent(event) }, onFormSubmit: function(form) { window.gaEvent('newsletter_subscription', 'czi_main_popup', document.location.pathname) } }); document.getElementById('hubspot-global-signup').remove(); }); </script> <div id="hbspt-form"></div> </div> </div> <div class="al-2023-wrap" al-2023> <div class="al-2022-nav sticky hidden"> <a href="#top" class="al-2022-nav__logo"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/nav-logo.svg" alt=""> </a> <div class="al-2022-nav__items"> <div class="al-2022-nav__item t-body--small is-active">2023</div> <a class="al-2022-nav__item t-body--small" href="https://chanzuckerberg.com/about/annual-letter/year-2022/" target="_blank">2022</a> <a class="al-2022-nav__item t-body--small" href="https://chanzuckerberg.com/about/annual-letter/year-2021/" target="_blank">2021</a> <a class="al-2022-nav__item t-body--small" href="https://chanzuckerberg.com/about/annual-letter/year-2020/" target="_blank">2020</a> <a class="al-2022-nav__item t-body--small" href="https://chanzuckerberg.com/about/annual-letter/year-2019/" target="_blank">2019</a> <a class="al-2022-nav__item t-body--small" href="https://chanzuckerberg.com/about/annual-letter/year-2018/" target="_blank">2018</a> <a class="al-2022-nav__item t-body--small" href="https://chanzuckerberg.com/newsroom/lessons-in-philanthropy-2017/" target="_blank">2017</a> <a class="al-2022-nav__item t-body--small" href="https://chanzuckerberg.com/newsroom/one-year-anniversary/" target="_blank">2016</a> <a class="al-2022-nav__item t-body--small" href="https://chanzuckerberg.com/about/letter-to-max/" target="_blank">2015</a> <div class="al-2022-social nav mobile-only"> <span class="t-body--x-small t-uppercase color--black">Share:</span> <a href="https://chanzuckerberg.com/about/annual-letter/year-2023/" class="button-social button-social--light button-social--share" social-share="share" aria-label="Copy link to clipboard." onclick=""></a> <a href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fchanzuckerberg.com%2Fabout%2Fannual-letter%2Fyear-2023" class="button-social button-social--light button-social--facebook" social-share="facebook" aria-label="Share on facebook. (Opens in a new window)" onclick=""></a> <a href="https://www.threads.net/@chanzuckerberginitiative/post/C0em768LLfl" class="button-social button-social--light button-social--threads" target="_blank" rel="noopener" aria-label="Share on Threads. (Opens in a new window)" onclick=""></a> <a href="https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Fchanzuckerberg.com%2Fabout%2Fannual-letter%2Fyear-2023" class="button-social button-social--light button-social--linkedin" social-share="linkedin" aria-label="Share on linkedin. (Opens in a new window)" onclick=""></a> <a href="https://twitter.com/intent/tweet?text=Read+how+%40ChanZuckerberg+is+using+AI+to+accelerate+scientific+discovery+%2B+what+led+to+this+moment+https%3A%2F%2Fchanzuckerberg.com%2Fabout%2Fannual-letter%2Fyear-2023" class="button-social button-social--light button-social--twitter" social-share="twitter" aria-label="Share on twitter. (Opens in a new window)" onclick=""></a> </div> </div> <div class="al-2022-social nav desktop-only"> <span class="t-body--small t-uppercase color--black">Share:</span> <a href="https://chanzuckerberg.com/about/annual-letter/year-2023/" class="button-social button-social--light button-social--share" social-share="share" aria-label="Copy link to clipboard." onclick=""></a> <a href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fchanzuckerberg.com%2Fabout%2Fannual-letter%2Fyear-2023" class="button-social button-social--light button-social--facebook" social-share="facebook" aria-label="Share on facebook. (Opens in a new window)" onclick=""></a> <a href="https://www.threads.net/@chanzuckerberginitiative/post/C0em768LLfl" class="button-social button-social--light button-social--threads" target="_blank" rel="noopener" aria-label="Share on Threads. (Opens in a new window)" onclick=""></a> <a href="https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Fchanzuckerberg.com%2Fabout%2Fannual-letter%2Fyear-2023" class="button-social button-social--light button-social--linkedin" social-share="linkedin" aria-label="Share on linkedin. (Opens in a new window)" onclick=""></a> <a href="https://twitter.com/intent/tweet?text=Read+how+%40ChanZuckerberg+is+using+AI+to+accelerate+scientific+discovery+%2B+what+led+to+this+moment+https%3A%2F%2Fchanzuckerberg.com%2Fabout%2Fannual-letter%2Fyear-2023" class="button-social button-social--light button-social--twitter" social-share="twitter" aria-label="Share on twitter. (Opens in a new window)" onclick=""></a> </div> <button class="al-2022-nav__toggle mobile-only"> <div class="al-2022-nav__toggle-current t-body--small color--black">2023</div> <div class="al-2022-nav__toggle-icon"> <svg class="toggle-open" width="13" height="8" viewBox="0 0 13 8" fill="none" xmlns="http://www.w3.org/2000/svg"> <line x1="0.233398" y1="0.671875" x2="12.4136" y2="0.671875" stroke="black"/> <line x1="0.233398" y1="3.67188" x2="12.4136" y2="3.67188" stroke="black"/> <line x1="0.233398" y1="6.67188" x2="12.4136" y2="6.67188" stroke="black"/> </svg> <svg class="toggle-close" width="11" height="10" viewBox="0 0 11 10" fill="none" xmlns="http://www.w3.org/2000/svg"> <line x1="1.37064" y1="0.511925" x2="9.98333" y2="9.12461" stroke="black"/> <line y1="-0.5" x2="12.1802" y2="-0.5" transform="matrix(0.707107 -0.707107 -0.707107 -0.707107 0.645996 8.67432)" stroke="black"/> </svg> </div> </button> <div class="scroll-indicator" scroll-indicator> <div class="scroll-indicator__fill"></div> </div> </div> <section class="al-2023-hero"> <div class="al-2023-hero__subhead"> <img class="al-2023-logomark" src="https://chanzuckerberg.com/wp-content/themes/czi/img/logo-minified.svg" alt=""> <h1 class="t-h5--semibold color--black">CZI Annual Letter 2023</h1> </div> <div class="al-2023-hero__headline"> <svg width="846" height="378" viewBox="0 0 846 378" fill="none" xmlns="http://www.w3.org/2000/svg" aria-labelledby="headingTitle"> <title id="headingTitle">Building for This Moment</title> <path d="M93.6338 144.138C93.6338 156.742 89.5874 166.426 81.4946 173.193C73.4017 179.959 63.1198 183.342 50.6489 183.342H8.65891C7.73022 183.342 7.00054 183.076 6.46986 182.546C5.93918 182.015 5.67384 181.285 5.67384 180.357V47.0237C5.67384 46.095 5.93918 45.3653 6.46986 44.8347C7.00054 44.304 7.73022 44.0386 8.65891 44.0386H44.6787C59.1397 44.0386 70.4166 47.2891 78.5095 53.7899C86.735 60.2907 90.8478 70.1082 90.8478 83.2425C90.8478 95.4481 87.0667 104.536 79.5045 110.506C78.8412 111.037 78.7085 111.501 79.1065 111.899C88.7914 119.329 93.6338 130.075 93.6338 144.138ZM44.2807 76.0784C43.4847 76.0784 43.0867 76.4764 43.0867 77.2724V97.1728C43.0867 97.9689 43.4847 98.3669 44.2807 98.3669H45.2757C51.2459 98.3669 54.2309 94.6521 54.2309 87.2226C54.2309 79.7931 51.2459 76.0784 45.2757 76.0784H44.2807ZM47.6638 151.302C50.1845 151.302 52.2409 150.241 53.8329 148.118C55.425 145.863 56.221 142.679 56.221 138.566C56.221 134.453 55.425 131.203 53.8329 128.815C52.3736 126.294 50.3835 125.033 47.8628 125.033H44.2807C43.4847 125.033 43.0867 125.431 43.0867 126.228V150.108C43.0867 150.904 43.4847 151.302 44.2807 151.302H47.6638ZM144.853 184.934C136.229 184.934 128.667 183.143 122.166 179.561C115.665 175.979 110.624 170.937 107.042 164.436C103.46 157.936 101.669 150.44 101.669 141.949V47.0237C101.669 46.095 101.934 45.3653 102.465 44.8347C102.995 44.304 103.725 44.0386 104.654 44.0386H136.096C137.025 44.0386 137.755 44.304 138.285 44.8347C138.816 45.3653 139.081 46.095 139.081 47.0237V145.531C139.081 147.786 139.612 149.577 140.674 150.904C141.735 152.231 143.128 152.894 144.853 152.894C146.577 152.894 147.904 152.231 148.833 150.904C149.894 149.577 150.425 147.786 150.425 145.531V47.0237C150.425 46.095 150.69 45.3653 151.221 44.8347C151.751 44.304 152.481 44.0386 153.41 44.0386H184.853C185.781 44.0386 186.511 44.304 187.042 44.8347C187.572 45.3653 187.838 46.095 187.838 47.0237V141.949C187.838 150.44 186.047 157.936 182.464 164.436C178.882 170.937 173.841 175.979 167.34 179.561C160.839 183.143 153.343 184.934 144.853 184.934ZM200.861 183.342C199.933 183.342 199.203 183.076 198.672 182.546C198.142 182.015 197.876 181.285 197.876 180.357V47.0237C197.876 46.095 198.142 45.3653 198.672 44.8347C199.203 44.304 199.933 44.0386 200.861 44.0386H232.304C233.233 44.0386 233.963 44.304 234.493 44.8347C235.024 45.3653 235.289 46.095 235.289 47.0237V180.357C235.289 181.285 235.024 182.015 234.493 182.546C233.963 183.076 233.233 183.342 232.304 183.342H200.861ZM248.669 183.342C247.741 183.342 247.011 183.076 246.48 182.546C245.949 182.015 245.684 181.285 245.684 180.357V47.0237C245.684 46.095 245.949 45.3653 246.48 44.8347C247.011 44.304 247.741 44.0386 248.669 44.0386H280.112C281.041 44.0386 281.77 44.304 282.301 44.8347C282.832 45.3653 283.097 46.095 283.097 47.0237V150.108C283.097 150.904 283.495 151.302 284.291 151.302H323.097C324.026 151.302 324.755 151.567 325.286 152.098C325.817 152.629 326.082 153.358 326.082 154.287V180.357C326.082 181.285 325.817 182.015 325.286 182.546C324.755 183.076 324.026 183.342 323.097 183.342H248.669ZM337.483 183.342C336.554 183.342 335.824 183.076 335.294 182.546C334.763 182.015 334.498 181.285 334.498 180.357V47.0237C334.498 46.095 334.763 45.3653 335.294 44.8347C335.824 44.304 336.554 44.0386 337.483 44.0386H376.687C385.443 44.0386 393.138 45.697 399.771 49.0138C406.537 52.3305 411.778 57.0403 415.492 63.1431C419.207 69.1132 421.065 76.012 421.065 83.8396V143.541C421.065 151.368 419.207 158.334 415.492 164.436C411.778 170.407 406.537 175.05 399.771 178.367C393.138 181.683 385.443 183.342 376.687 183.342H337.483ZM371.911 150.108C371.911 150.904 372.309 151.302 373.105 151.302L375.891 151.103C378.013 150.97 379.804 149.975 381.264 148.118C382.723 146.261 383.519 143.873 383.652 140.954V86.2276C383.652 83.1762 382.922 80.7218 381.463 78.8644C380.003 77.0071 378.08 76.0784 375.692 76.0784H373.105C372.309 76.0784 371.911 76.4764 371.911 77.2724V150.108ZM433.681 183.342C432.752 183.342 432.023 183.076 431.492 182.546C430.961 182.015 430.696 181.285 430.696 180.357V47.0237C430.696 46.095 430.961 45.3653 431.492 44.8347C432.023 44.304 432.752 44.0386 433.681 44.0386H465.124C466.053 44.0386 466.782 44.304 467.313 44.8347C467.844 45.3653 468.109 46.095 468.109 47.0237V180.357C468.109 181.285 467.844 182.015 467.313 182.546C466.782 183.076 466.053 183.342 465.124 183.342H433.681ZM536.215 47.0237C536.215 46.095 536.48 45.3653 537.011 44.8347C537.542 44.304 538.272 44.0386 539.2 44.0386H570.245C571.174 44.0386 571.903 44.304 572.434 44.8347C572.965 45.3653 573.23 46.095 573.23 47.0237V180.357C573.23 181.285 572.965 182.015 572.434 182.546C571.903 183.076 571.174 183.342 570.245 183.342H534.822C533.097 183.342 532.036 182.479 531.638 180.755L516.514 120.456C516.381 120.058 516.116 119.859 515.718 119.859C515.32 119.859 515.121 120.125 515.121 120.655L515.519 180.357C515.519 181.285 515.253 182.015 514.723 182.546C514.192 183.076 513.462 183.342 512.534 183.342H481.489C480.56 183.342 479.831 183.076 479.3 182.546C478.769 182.015 478.504 181.285 478.504 180.357V47.0237C478.504 46.095 478.769 45.3653 479.3 44.8347C479.831 44.304 480.56 44.0386 481.489 44.0386H516.514C518.238 44.0386 519.3 44.901 519.698 46.6257L535.021 107.123C535.154 107.654 535.419 107.919 535.817 107.919C536.215 107.919 536.414 107.654 536.414 107.123L536.215 47.0237ZM626.03 184.934C612.896 184.934 602.348 181.285 594.388 173.989C586.428 166.559 582.448 156.675 582.448 144.337V82.8445C582.448 70.5062 586.428 60.6887 594.388 53.3919C602.348 46.095 612.896 42.4466 626.03 42.4466C634.653 42.4466 642.216 44.105 648.716 47.4217C655.35 50.7385 660.458 55.5146 664.04 61.7501C667.755 67.8529 669.612 75.017 669.612 83.2425V89.8097C669.612 90.7384 669.347 91.4681 668.816 91.9987C668.285 92.5294 667.556 92.7948 666.627 92.7948H635.184C634.255 92.7948 633.526 92.5294 632.995 91.9987C632.464 91.4681 632.199 90.7384 632.199 89.8097V82.8445C632.199 80.3238 631.602 78.3338 630.408 76.8744C629.347 75.2824 627.887 74.4863 626.03 74.4863C624.173 74.4863 622.647 75.2824 621.453 76.8744C620.392 78.3338 619.861 80.3238 619.861 82.8445V144.536C619.861 147.057 620.392 149.113 621.453 150.705C622.647 152.164 624.173 152.894 626.03 152.894C627.887 152.894 629.347 152.164 630.408 150.705C631.602 149.113 632.199 147.057 632.199 144.536V134.785C632.199 133.989 631.801 133.591 631.005 133.591H629.413C628.484 133.591 627.755 133.325 627.224 132.795C626.693 132.264 626.428 131.534 626.428 130.606V107.72C626.428 106.791 626.693 106.062 627.224 105.531C627.755 105 628.484 104.735 629.413 104.735H666.627C667.556 104.735 668.285 105 668.816 105.531C669.347 106.062 669.612 106.791 669.612 107.72V144.337C669.612 152.43 667.755 159.594 664.04 165.829C660.458 171.932 655.35 176.642 648.716 179.959C642.216 183.275 634.653 184.934 626.03 184.934Z" fill="black"/> <path d="M73.0492 288.124C74.6754 287.885 76.182 287.455 77.5691 286.833C79.004 286.211 80.3671 285.494 81.6585 284.68C82.9499 283.819 84.1935 282.935 85.3892 282.026C86.585 281.069 87.7807 280.184 88.9765 279.371C88.7373 281.38 87.9481 283.054 86.6089 284.393C85.3175 285.733 83.8348 286.928 82.1607 287.981C81.3476 288.459 80.5106 288.937 79.6497 289.416C78.7888 289.894 77.88 290.276 76.9234 290.563C76.0146 290.85 75.058 291.018 74.0536 291.066C73.0492 291.066 71.9969 290.874 70.8969 290.492C69.7968 293.075 69.0315 295.873 68.601 298.886C68.1228 301.899 67.8597 305.008 67.8119 308.213C68.1467 308.643 68.4815 309.169 68.8163 309.791C69.1033 310.461 69.1989 311.082 69.1033 311.656C68.4336 311.8 67.8597 311.752 67.3814 311.513C66.9031 311.274 66.5205 310.891 66.2335 310.365C65.8987 309.887 65.6356 309.337 65.4443 308.715C65.2051 308.093 64.9899 307.447 64.7986 306.778C64.7986 305.104 64.8464 303.549 64.9421 302.114C64.9899 300.632 65.1334 299.221 65.3725 297.881C65.5639 296.494 65.8269 295.131 66.1617 293.792C66.4965 292.453 66.8792 291.042 67.3096 289.559C67.2618 289.463 67.214 289.416 67.1662 289.416C67.1183 289.368 67.0944 289.296 67.0944 289.2C66.9509 288.961 66.7596 288.746 66.5205 288.555C66.2813 288.363 66.0661 288.148 65.8748 287.909C65.6834 287.67 65.54 287.431 65.4443 287.191C65.3486 286.904 65.3725 286.57 65.516 286.187C65.8508 285.948 66.2335 285.948 66.6639 286.187C67.0466 286.378 67.4292 286.498 67.8119 286.546C68.8163 283.628 69.8685 280.687 70.9686 277.721C72.0687 274.708 73.2405 271.79 74.4841 268.968C75.7755 266.146 77.1625 263.444 78.6453 260.861C80.128 258.231 81.7781 255.839 83.5956 253.687C84.5522 253.304 85.5566 253.352 86.6089 253.83C87.709 254.261 88.4503 254.883 88.833 255.696C88.5938 258.565 87.9242 261.459 86.8241 264.377C85.724 267.247 84.3848 270.092 82.8064 272.914C81.2759 275.688 79.6258 278.367 77.8561 280.95C76.1342 283.532 74.5319 285.924 73.0492 288.124ZM73.7666 280.806C76.206 277.171 78.5257 273.417 80.7259 269.542C82.926 265.668 84.6718 261.459 85.9632 256.915C85.8675 256.772 85.748 256.724 85.6045 256.772C84.3131 258.446 83.0695 260.263 81.8738 262.224C80.7259 264.138 79.6497 266.146 78.6453 268.251C77.6408 270.308 76.7321 272.412 75.919 274.564C75.1059 276.669 74.3884 278.75 73.7666 280.806ZM99.0173 285.254C99.8304 284.92 100.572 284.537 101.241 284.106C101.911 283.628 102.533 283.126 103.107 282.6C103.729 282.074 104.35 281.548 104.972 281.021C105.594 280.447 106.24 279.945 106.909 279.515C106.861 280.902 106.574 282.145 106.048 283.246C105.522 284.298 104.829 285.23 103.968 286.044C103.107 286.809 102.102 287.478 100.954 288.052C99.8543 288.579 98.6586 289.009 97.3672 289.344C96.7454 290.109 96.1715 290.922 95.6453 291.783C95.167 292.644 94.6409 293.481 94.0669 294.294C93.493 295.059 92.8473 295.777 92.1298 296.446C91.4124 297.116 90.5276 297.618 89.4753 297.953C88.3752 297.905 87.5382 297.594 86.9643 297.02C86.3425 296.446 85.7446 295.873 85.1706 295.299C84.7402 293.051 84.6923 290.97 85.0272 289.057C85.3141 287.096 85.8163 285.254 86.5338 283.532C87.2512 281.811 88.0882 280.161 89.0448 278.582C90.0014 277.004 90.9341 275.449 91.8429 273.919C92.369 273.249 93.1104 272.962 94.0669 273.058C95.0235 273.153 95.9562 273.393 96.865 273.775C97.4868 274.349 97.989 275.091 98.3716 275.999C98.7542 276.908 99.0173 277.913 99.1608 279.013C99.3521 280.065 99.4239 281.141 99.376 282.241C99.3282 283.341 99.2086 284.346 99.0173 285.254ZM93.2778 279.3C93.0864 279.826 92.943 280.471 92.8473 281.237C92.7516 282.002 92.7277 282.743 92.7755 283.461C92.8234 284.178 92.9669 284.824 93.206 285.398C93.493 285.924 93.9235 286.283 94.4974 286.474C95.0235 284.991 95.454 283.485 95.7888 281.954C96.1236 280.424 96.004 278.821 95.4301 277.147C94.9518 277.434 94.5931 277.817 94.3539 278.295C94.1626 278.726 93.8039 279.06 93.2778 279.3ZM87.8969 295.299C89.1883 294.438 90.2645 293.361 91.1254 292.07C91.9864 290.779 92.8234 289.463 93.6365 288.124C92.9669 287.598 92.3451 287.024 91.7711 286.402C91.245 285.78 90.7189 285.159 90.1928 284.537C89.6188 286.067 89.0448 287.742 88.4709 289.559C87.8969 291.329 87.7056 293.242 87.8969 295.299ZM121.981 273.56C122.172 273.99 122.268 274.493 122.268 275.067C122.315 275.641 122.1 276.023 121.622 276.215C121.191 276.071 120.928 275.784 120.833 275.354C120.737 274.923 120.522 274.612 120.187 274.421C118.8 275.043 117.461 276.047 116.169 277.434C114.926 278.773 113.754 280.256 112.654 281.882C111.602 283.509 110.645 285.159 109.784 286.833C108.923 288.507 108.206 289.989 107.632 291.281C106.962 292.811 106.292 294.366 105.623 295.944C104.953 297.523 103.949 298.838 102.61 299.89C102.036 299.651 101.581 299.316 101.246 298.886C100.864 298.455 100.409 298.073 99.8833 297.738C100.218 295.586 100.672 293.529 101.246 291.568C101.773 289.559 102.394 287.598 103.112 285.685C103.781 283.724 104.475 281.787 105.192 279.874C105.91 277.913 106.603 275.928 107.273 273.919C107.703 273.967 108.11 273.895 108.493 273.704C108.923 273.512 109.306 273.417 109.641 273.417C110.023 273.369 110.358 273.488 110.645 273.775C110.98 274.062 111.219 274.708 111.362 275.712C110.98 276.573 110.621 277.482 110.286 278.439C109.951 279.395 109.545 280.28 109.067 281.093C109.784 280.376 110.549 279.419 111.362 278.223C112.223 276.98 113.156 275.88 114.16 274.923C115.213 273.919 116.361 273.225 117.604 272.843C118.896 272.412 120.354 272.651 121.981 273.56ZM146.822 260.718C148.831 260.431 151.079 260.072 153.566 259.642C156.101 259.211 158.66 258.9 161.243 258.709C163.873 258.47 166.48 258.398 169.063 258.494C171.693 258.542 174.133 258.924 176.381 259.642C176.716 260.024 177.122 260.335 177.6 260.574C178.079 260.813 178.342 261.268 178.39 261.937C177.72 261.985 177.098 262.009 176.524 262.009C175.95 262.009 175.305 261.818 174.587 261.435C172.196 261.292 169.709 261.268 167.126 261.363C164.591 261.411 162.032 261.579 159.449 261.866C156.914 262.153 154.403 262.535 151.916 263.014C149.477 263.492 147.181 264.042 145.028 264.664C143.211 268.825 141.369 273.201 139.504 277.793C137.687 282.337 135.989 286.976 134.41 291.711C134.362 292.859 134.219 293.912 133.98 294.868C133.741 295.825 133.645 296.925 133.693 298.168C134.362 298.025 135.128 297.523 135.989 296.662C136.85 295.753 137.734 294.772 138.643 293.72C139.552 292.62 140.413 291.568 141.226 290.563C142.039 289.559 142.709 288.866 143.235 288.483C144.144 287.048 145.196 285.637 146.392 284.25C147.587 282.863 148.735 281.715 149.835 280.806C149.74 281.763 149.501 282.672 149.118 283.532C148.735 284.346 148.305 285.159 147.826 285.972C147.348 286.785 146.846 287.598 146.32 288.411C145.794 289.176 145.363 289.989 145.028 290.85C143.976 292.333 142.876 293.768 141.728 295.155C140.58 296.542 139.456 297.977 138.356 299.46C137.734 300.177 137.065 300.632 136.347 300.823C135.63 300.966 134.912 300.942 134.195 300.751C133.478 300.512 132.832 300.129 132.258 299.603C131.636 299.029 131.11 298.384 130.68 297.666L130.106 294.438C130.488 291.951 131.062 289.487 131.827 287.048C132.545 284.609 133.358 282.217 134.267 279.874C135.128 277.482 136.06 275.162 137.065 272.914C138.069 270.619 139.05 268.347 140.006 266.099C137.28 266.72 134.649 267.39 132.114 268.107C129.532 268.777 126.949 269.231 124.366 269.471C123.696 269.279 123.099 268.921 122.572 268.394C122.381 267.725 122.238 267.127 122.142 266.601C122.046 266.027 121.951 265.429 121.855 264.807C122.62 264.712 123.386 264.64 124.151 264.592C124.916 264.544 125.586 264.496 126.16 264.448C126.208 264.688 126.208 264.855 126.16 264.951C126.112 265.046 126.04 265.142 125.944 265.238C125.849 265.286 125.777 265.357 125.729 265.453C125.634 265.549 125.61 265.692 125.657 265.883C128.145 265.453 130.632 264.927 133.119 264.305C135.558 263.683 138.261 262.966 141.226 262.153C141.896 261.387 142.493 260.263 143.02 258.781C143.546 257.25 144.024 255.863 144.455 254.62C144.646 254.093 145.005 253.711 145.531 253.472C146.057 253.185 146.583 253.065 147.109 253.113C147.683 253.113 148.185 253.304 148.616 253.687C149.046 254.022 149.285 254.572 149.333 255.337C149.333 255.863 149.214 256.341 148.974 256.772C148.783 257.154 148.52 257.561 148.185 257.991C147.898 258.374 147.611 258.805 147.324 259.283C147.037 259.713 146.87 260.192 146.822 260.718ZM158.971 251.965C159.832 252.108 160.573 252.252 161.195 252.395C161.817 252.491 162.319 252.945 162.702 253.759C162.128 255.911 161.458 257.991 160.693 260C159.928 261.961 159.138 263.922 158.325 265.883C157.512 267.797 156.699 269.758 155.886 271.766C155.073 273.727 154.355 275.784 153.734 277.936C154.164 277.649 154.571 277.291 154.953 276.86C155.384 276.382 155.838 275.928 156.316 275.497C156.795 275.019 157.321 274.588 157.895 274.206C158.469 273.823 159.114 273.584 159.832 273.488C160.167 273.488 160.454 273.56 160.693 273.704C160.932 273.847 161.147 274.014 161.339 274.206C161.53 274.349 161.721 274.493 161.912 274.636C162.104 274.78 162.367 274.875 162.702 274.923C163.036 276.454 163.084 277.889 162.845 279.228C162.606 280.519 162.295 281.835 161.912 283.174C161.578 284.465 161.267 285.828 160.98 287.263C160.693 288.65 160.669 290.205 160.908 291.927C161.243 291.974 161.506 291.903 161.697 291.711C161.889 291.52 162.032 291.305 162.128 291.066C162.223 290.827 162.319 290.635 162.415 290.492C162.558 290.3 162.773 290.253 163.06 290.348C163.252 289.392 163.73 288.483 164.495 287.622C165.308 286.761 165.978 285.876 166.504 284.967C166.935 284.633 167.317 284.25 167.652 283.819C167.987 283.389 168.298 282.959 168.585 282.528C168.92 282.05 169.254 281.595 169.589 281.165C169.924 280.734 170.331 280.376 170.809 280.089C170.617 281.332 170.307 282.552 169.876 283.748C169.493 284.896 169.039 286.02 168.513 287.12C167.987 288.22 167.413 289.296 166.791 290.348C166.217 291.353 165.643 292.357 165.069 293.361C164.543 293.648 164.065 293.983 163.634 294.366C163.204 294.701 162.654 294.916 161.984 295.012C160.31 294.39 159.162 293.433 158.541 292.142C157.967 290.803 157.656 289.32 157.608 287.694C157.608 286.02 157.799 284.298 158.182 282.528C158.564 280.711 158.947 279.013 159.33 277.434C157.895 278.391 156.603 279.587 155.455 281.021C154.308 282.409 153.231 283.963 152.227 285.685C151.27 287.359 150.386 289.129 149.572 290.994C148.759 292.811 147.994 294.629 147.277 296.446C147.324 297.212 147.253 297.834 147.061 298.312C146.87 298.79 146.655 299.292 146.416 299.818C145.698 299.627 145.124 299.388 144.694 299.101C144.216 298.766 143.761 298.288 143.331 297.666C143.235 297.14 143.259 296.757 143.402 296.518C143.546 296.231 143.594 295.849 143.546 295.37C145.794 288.674 148.09 282.074 150.433 275.569C152.777 269.016 155.264 262.511 157.895 256.054C158.134 255.767 158.134 255.552 157.895 255.409C157.656 255.217 157.656 255.026 157.895 254.835C157.895 254.452 157.943 254.141 158.038 253.902C158.182 253.663 158.325 253.472 158.469 253.328C158.612 253.137 158.732 252.945 158.827 252.754C158.971 252.515 159.019 252.252 158.971 251.965ZM176.411 263.659C177.128 263.803 177.607 264.114 177.846 264.592C178.085 265.07 178.157 265.596 178.061 266.17C177.965 266.696 177.726 267.199 177.344 267.677C176.961 268.155 176.483 268.418 175.909 268.466C175.431 268.371 175.072 268.131 174.833 267.749C174.594 267.366 174.354 267.007 174.115 266.673C174.115 265.812 174.354 265.166 174.833 264.735C175.311 264.305 175.837 263.946 176.411 263.659ZM175.191 276.358C175.239 276.884 175.215 277.219 175.12 277.362C175.072 277.506 175.144 277.769 175.335 278.152C174.187 280.878 172.943 283.628 171.604 286.402C170.313 289.129 169.356 291.998 168.734 295.012C169.069 294.964 169.404 294.82 169.739 294.581C170.074 294.342 170.385 294.055 170.671 293.72C171.006 293.385 171.341 293.075 171.676 292.788C172.059 292.453 172.441 292.19 172.824 291.998C173.637 290.755 174.546 289.655 175.55 288.698C176.602 287.742 177.607 286.737 178.563 285.685C178.946 285.111 179.376 284.609 179.855 284.178C180.381 283.7 180.907 283.198 181.433 282.672C181.911 282.193 182.366 281.667 182.796 281.093C183.275 280.471 183.849 280.161 184.518 280.161C183.992 281.356 183.155 282.863 182.007 284.68C180.907 286.45 179.663 288.244 178.276 290.061C176.937 291.879 175.574 293.553 174.187 295.083C172.848 296.566 171.676 297.618 170.671 298.24C169.811 298.288 169.117 298.24 168.591 298.097C168.017 297.905 167.539 297.642 167.156 297.307C166.726 296.973 166.367 296.59 166.08 296.16C165.793 295.681 165.482 295.179 165.147 294.653C165.147 292.883 165.362 291.233 165.793 289.703C166.175 288.172 166.654 286.689 167.228 285.254C167.802 283.819 168.4 282.409 169.021 281.021C169.643 279.587 170.145 278.104 170.528 276.573C171.006 275.856 171.748 275.473 172.752 275.425C173.756 275.378 174.57 275.688 175.191 276.358ZM198.559 272.34C198.559 273.44 198.344 274.397 197.914 275.21C197.531 276.023 197.077 276.836 196.55 277.649C196.072 278.415 195.594 279.228 195.116 280.089C194.637 280.902 194.35 281.858 194.255 282.959C193.585 282.815 193.083 282.528 192.748 282.098C192.413 281.619 192.031 281.189 191.6 280.806C191.696 279.754 191.696 278.797 191.6 277.936C190.596 278.558 189.543 279.419 188.443 280.519C187.343 281.571 186.482 282.743 185.861 284.035C185.765 284.322 185.789 284.537 185.932 284.68C186.076 284.776 186.1 284.967 186.004 285.254C186.721 285.78 187.487 286.283 188.3 286.761C189.161 287.191 189.974 287.67 190.739 288.196C191.504 288.674 192.222 289.224 192.892 289.846C193.609 290.42 194.183 291.113 194.613 291.927C194.566 292.453 194.542 292.788 194.542 292.931C194.542 293.027 194.566 293.338 194.613 293.864L193.752 295.514C192.748 296.088 191.576 296.733 190.237 297.451C188.898 298.121 187.511 298.671 186.076 299.101C184.641 299.532 183.206 299.747 181.771 299.747C180.288 299.699 178.949 299.245 177.753 298.384C177.706 297.857 177.634 297.379 177.538 296.949C177.395 296.47 177.275 296.016 177.179 295.586C177.084 295.155 177.036 294.701 177.036 294.222C176.988 293.744 177.06 293.218 177.251 292.644C177.873 292.261 178.471 291.855 179.045 291.424C179.619 290.946 180.193 290.492 180.767 290.061C181.293 289.583 181.867 289.152 182.489 288.77C183.11 288.339 183.804 288.005 184.569 287.765C184.33 288.579 183.947 289.272 183.421 289.846C182.895 290.42 182.369 290.994 181.843 291.568C181.269 292.094 180.791 292.668 180.408 293.29C179.978 293.912 179.762 294.653 179.762 295.514C180.623 295.609 181.58 295.586 182.632 295.442C183.684 295.251 184.713 294.988 185.717 294.653C186.769 294.27 187.75 293.84 188.659 293.361C189.615 292.835 190.404 292.285 191.026 291.711C190.213 291.042 189.376 290.42 188.515 289.846C187.654 289.224 186.698 288.65 185.645 288.124C185.311 287.837 185.024 287.478 184.784 287.048C184.593 286.57 184.426 286.091 184.282 285.613C184.139 285.087 183.995 284.561 183.852 284.035C183.708 283.509 183.541 283.03 183.35 282.6C183.397 281.882 183.517 281.261 183.708 280.734C183.947 280.208 184.187 279.73 184.426 279.3C184.713 278.869 185.024 278.439 185.358 278.008C185.693 277.578 186.028 277.076 186.363 276.502C187.176 276.023 187.893 275.425 188.515 274.708C189.137 273.99 189.783 273.321 190.452 272.699C191.17 272.077 191.983 271.551 192.892 271.121C193.8 270.69 194.924 270.499 196.263 270.547C196.694 270.834 197.077 271.145 197.411 271.479C197.794 271.766 198.177 272.053 198.559 272.34Z" fill="black"/> <path d="M301.682 216.339C302.478 214.879 303.672 214.149 305.265 214.149H336.309C337.238 214.149 337.968 214.415 338.498 214.946C339.029 215.476 339.294 216.206 339.294 217.135V350.468C339.294 351.396 339.029 352.126 338.498 352.657C337.968 353.187 337.238 353.453 336.309 353.453H304.866C303.938 353.453 303.208 353.187 302.677 352.657C302.147 352.126 301.881 351.396 301.881 350.468V269.473C301.881 268.942 301.682 268.61 301.284 268.478C301.019 268.345 300.754 268.544 300.488 269.075L289.145 288.179L287.155 291.761H286.956L273.822 269.075C273.556 268.544 273.225 268.345 272.827 268.478C272.561 268.478 272.429 268.809 272.429 269.473V350.468C272.429 351.396 272.163 352.126 271.633 352.657C271.102 353.187 270.372 353.453 269.444 353.453H238.001C237.072 353.453 236.343 353.187 235.812 352.657C235.281 352.126 235.016 351.396 235.016 350.468V217.135C235.016 216.206 235.281 215.476 235.812 214.946C236.343 214.415 237.072 214.149 238.001 214.149H269.046C270.77 214.149 271.964 214.879 272.628 216.339L286.558 241.811C286.823 242.209 287.089 242.474 287.354 242.607C287.752 242.607 288.017 242.342 288.15 241.811L301.682 216.339ZM391.713 355.045C378.314 355.045 367.567 351.197 359.475 343.502C351.514 335.808 347.534 325.459 347.534 312.458V255.144C347.534 242.143 351.514 231.795 359.475 224.1C367.567 216.405 378.314 212.557 391.713 212.557C405.113 212.557 415.793 216.405 423.753 224.1C431.846 231.795 435.892 242.143 435.892 255.144V312.458C435.892 325.459 431.846 335.808 423.753 343.502C415.793 351.197 405.113 355.045 391.713 355.045ZM391.713 323.005C393.836 323.005 395.494 322.209 396.688 320.617C397.882 319.025 398.479 316.836 398.479 314.05V253.552C398.479 250.766 397.882 248.577 396.688 246.985C395.494 245.393 393.836 244.597 391.713 244.597C389.591 244.597 387.932 245.393 386.738 246.985C385.544 248.577 384.947 250.766 384.947 253.552V314.05C384.947 316.836 385.544 319.025 386.738 320.617C387.932 322.209 389.591 323.005 391.713 323.005ZM510.793 216.339C511.589 214.879 512.783 214.149 514.375 214.149H545.419C546.348 214.149 547.078 214.415 547.608 214.946C548.139 215.476 548.404 216.206 548.404 217.135V350.468C548.404 351.396 548.139 352.126 547.608 352.657C547.078 353.187 546.348 353.453 545.419 353.453H513.977C513.048 353.453 512.318 353.187 511.788 352.657C511.257 352.126 510.992 351.396 510.992 350.468V269.473C510.992 268.942 510.793 268.61 510.395 268.478C510.129 268.345 509.864 268.544 509.599 269.075L498.255 288.179L496.265 291.761H496.066L482.932 269.075C482.667 268.544 482.335 268.345 481.937 268.478C481.672 268.478 481.539 268.809 481.539 269.473V350.468C481.539 351.396 481.274 352.126 480.743 352.657C480.212 353.187 479.483 353.453 478.554 353.453H447.111C446.182 353.453 445.453 353.187 444.922 352.657C444.391 352.126 444.126 351.396 444.126 350.468V217.135C444.126 216.206 444.391 215.476 444.922 214.946C445.453 214.415 446.182 214.149 447.111 214.149H478.156C479.881 214.149 481.075 214.879 481.738 216.339L495.668 241.811C495.934 242.209 496.199 242.474 496.464 242.607C496.862 242.607 497.128 242.342 497.26 241.811L510.793 216.339ZM637.44 243.204C637.44 244.133 637.175 244.863 636.644 245.393C636.114 245.924 635.384 246.189 634.455 246.189H596.445C595.649 246.189 595.251 246.587 595.251 247.383V266.488C595.251 267.284 595.649 267.682 596.445 267.682H616.147C617.076 267.682 617.805 267.947 618.336 268.478C618.867 269.008 619.132 269.738 619.132 270.667V296.736C619.132 297.665 618.867 298.395 618.336 298.925C617.805 299.456 617.076 299.721 616.147 299.721H596.445C595.649 299.721 595.251 300.119 595.251 300.915V320.219C595.251 321.015 595.649 321.413 596.445 321.413H634.455C635.384 321.413 636.114 321.678 636.644 322.209C637.175 322.74 637.44 323.469 637.44 324.398V350.468C637.44 351.396 637.175 352.126 636.644 352.657C636.114 353.187 635.384 353.453 634.455 353.453H560.824C559.895 353.453 559.165 353.187 558.635 352.657C558.104 352.126 557.839 351.396 557.839 350.468V217.135C557.839 216.206 558.104 215.476 558.635 214.946C559.165 214.415 559.895 214.149 560.824 214.149H634.455C635.384 214.149 636.114 214.415 636.644 214.946C637.175 215.476 637.44 216.206 637.44 217.135V243.204ZM703.975 217.135C703.975 216.206 704.24 215.476 704.771 214.946C705.301 214.415 706.031 214.149 706.96 214.149H738.004C738.933 214.149 739.663 214.415 740.193 214.946C740.724 215.476 740.989 216.206 740.989 217.135V350.468C740.989 351.396 740.724 352.126 740.193 352.657C739.663 353.187 738.933 353.453 738.004 353.453H702.582C700.857 353.453 699.796 352.59 699.398 350.866L684.273 290.567C684.141 290.169 683.875 289.97 683.477 289.97C683.079 289.97 682.88 290.236 682.88 290.766L683.278 350.468C683.278 351.396 683.013 352.126 682.482 352.657C681.951 353.187 681.222 353.453 680.293 353.453H649.248C648.32 353.453 647.59 353.187 647.059 352.657C646.529 352.126 646.263 351.396 646.263 350.468V217.135C646.263 216.206 646.529 215.476 647.059 214.946C647.59 214.415 648.32 214.149 649.248 214.149H684.273C685.998 214.149 687.059 215.012 687.457 216.737L702.781 277.234C702.913 277.765 703.179 278.03 703.577 278.03C703.975 278.03 704.174 277.765 704.174 277.234L703.975 217.135ZM838.963 214.149C839.892 214.149 840.622 214.415 841.152 214.946C841.683 215.476 841.948 216.206 841.948 217.135V243.204C841.948 244.133 841.683 244.863 841.152 245.393C840.622 245.924 839.892 246.189 838.963 246.189H815.481C814.685 246.189 814.287 246.587 814.287 247.383V350.468C814.287 351.396 814.021 352.126 813.491 352.657C812.96 353.187 812.23 353.453 811.302 353.453H779.859C778.93 353.453 778.201 353.187 777.67 352.657C777.139 352.126 776.874 351.396 776.874 350.468V247.383C776.874 246.587 776.476 246.189 775.68 246.189H752.794C751.866 246.189 751.136 245.924 750.605 245.393C750.075 244.863 749.809 244.133 749.809 243.204V217.135C749.809 216.206 750.075 215.476 750.605 214.946C751.136 214.415 751.866 214.149 752.794 214.149H838.963Z" fill="black"/> </svg> </div> </section> <section class="al-2023-letter top"> <div class="content-story__text "> <div class="content-block__body t-body--large"> <img class="al-2023-mp" src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/mp-2.jpg" alt="Photo of Priscilla Chan and Mark Zuckerberg"> <p class="al-2023-dear-friends t-h3--semibold">Dear friends,</p> <p>Looking forward to 2024, we see an incredible opportunity to use artificial intelligence (AI) to accelerate the progress of our work at the Chan Zuckerberg Initiative.</p> <p style="clear: left;">In the early days of CZI, we didn't know the exact path we were going to take, but we had a sense of where to start. We listened to our partners in the field and learned about the challenges they faced. Then, we explored the problems that CZI — as a philanthropic organization with a builder mentality staffed with incredible scientists, educators, full-stack technology teams, and mission-driven people who power our work — was uniquely positioned to tackle. We call these CZI-shaped problems.</p> <p>In science, we've spent the last seven years exploring and refining the CZI-shaped problems we will tackle. When we launched our science work in 2016, we set a goal to help scientists cure, prevent, or manage all diseases by the end of the century. We knew accomplishing this goal required a better understanding of the cell, the fundamental unit of life in which many diseases originate. To make progress in filling those gaps in knowledge, we needed to strengthen and increase the field's understanding of basic cellular biology.</p> <p>To put it another way: how can you debug the code if you can't examine all the lines of code? We want to equip scientists with that same ability to step through the code of our bodies, which requires new tools to observe, measure and analyze the processes that keep us healthy and the errors that cause disease.</p> <p>So, we started supporting researchers in gathering new information about our cells, the tissues and organs they form, and what changes occur between health and disease. We built open source software tools that helped scientists better access, explore and annotate that data. We also built scientific institutions to help address some of the biggest challenges in cell biology and imaging. And now, we are building a high-performance AI computing system to power predictive models of healthy and diseased human cells.</p> <p>We believe this convergence across data, tools and AI will unlock new scientific understanding and discoveries about how cells behave and function. This is the next step toward our goal to help end disease as we know it.</p> <p>When people first hear this goal, they either think it's impossible or inevitable. We think the truth lies in the middle — it can happen, but only if we build the tools and fund the science to make new discoveries that help change the way scientists can see the world.</p> <p>Take a look at how we've been building for this moment by following the path of two of our earliest bets in science: single-cell biology and our multidisciplinary Biohub model.</p> </div> </div> <div class="al-2023-letter__right desktop-only"> <div> <a href="#timeline" class="explore-cta"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/explore.svg" alt=""> </a> </div> </div> </section> <section class="al-2023-visual" id="timeline"> <div class="al-2023-chart"> <div class="al-2023-chart-inner"> <svg width="835" height="619" viewBox="0 0 835 619" fill="none" xmlns="http://www.w3.org/2000/svg"> <g id="Comp file" clip-path="url(#clip0_42_3042)"> <g id="inactive lines"> <path id="Vector 280" d="M435.521 143.586L435.521 541.645" stroke="#F9F9F9" stroke-width="4" /> <path id="Vector 281" d="M387.433 424C386.328 424 385.433 424.895 385.433 426C385.433 427.104 386.328 428 387.433 428L387.433 424ZM427.611 438.916L425.611 438.916L427.611 438.916ZM414.695 426L414.695 424L414.695 426ZM425.611 438.916L425.611 541.644L429.611 541.644L429.611 438.916L425.611 438.916ZM414.695 424L387.433 424L387.433 428L414.695 428L414.695 424ZM429.611 438.916C429.611 430.678 422.933 424 414.695 424L414.695 428C420.724 428 425.611 432.887 425.611 438.916L429.611 438.916Z" fill="#F9F9F9" /> <path id="Vector 320" d="M344.486 239.706C343.421 239.41 342.319 240.032 342.022 241.096C341.726 242.16 342.348 243.263 343.412 243.559L344.486 239.706ZM431.395 275.809L429.395 275.809L431.395 275.809ZM429.395 275.809L429.395 541.645L433.395 541.645L433.395 275.809L429.395 275.809ZM422.483 261.44L344.486 239.706L343.412 243.559L421.409 265.293L422.483 261.44ZM433.395 275.809C433.395 269.113 428.933 263.237 422.483 261.44L421.409 265.293C426.13 266.609 429.395 270.909 429.395 275.809L433.395 275.809Z" fill="#F9F9F9" /> <path id="Vector 319" d="M347.589 245.712C346.933 244.824 345.68 244.636 344.792 245.292C343.903 245.948 343.715 247.201 344.371 248.089L347.589 245.712ZM385.78 300.782L384.171 301.97L385.78 300.782ZM390.307 428L390.307 308.456L386.307 308.456L386.307 428L390.307 428ZM387.389 299.594L347.589 245.712L344.371 248.089L384.171 301.97L387.389 299.594ZM390.307 308.456C390.307 305.266 389.284 302.16 387.389 299.594L384.171 301.97C385.558 303.848 386.307 306.121 386.307 308.456L390.307 308.456Z" fill="#F9F9F9" /> <path id="Vector 316" d="M341.858 240.017C340.927 239.423 339.691 239.696 339.096 240.627C338.502 241.558 338.775 242.794 339.706 243.389L341.858 240.017ZM406.102 283.388L405.026 285.074L406.102 283.388ZM424.986 383.336L567.882 383.335L567.882 379.335L424.985 379.336L424.986 383.336ZM414.069 368.419L414.069 294.276L410.069 294.276L410.069 368.419L414.069 368.419ZM407.177 281.702L341.858 240.017L339.706 243.389L405.026 285.074L407.177 281.702ZM414.069 294.276C414.069 289.183 411.471 284.442 407.177 281.702L405.026 285.074C408.168 287.079 410.069 290.548 410.069 294.276L414.069 294.276ZM424.985 379.336C418.957 379.336 414.069 374.448 414.069 368.419L410.069 368.419C410.069 376.657 416.748 383.336 424.986 383.336L424.985 379.336Z" fill="#F9F9F9" /> <path id="Vector 292" d="M631.374 102.625C631.374 103.73 630.479 104.625 629.374 104.625C628.27 104.625 627.374 103.73 627.374 102.625L631.374 102.625ZM441.574 48.8478L441.574 66.8789L437.574 66.8789L437.574 48.8478L441.574 48.8478ZM452.49 77.7951L616.458 77.7951L616.458 81.7951L452.49 81.7951L452.49 77.7951ZM631.374 92.7113L631.374 102.625L627.374 102.625L627.374 92.7113L631.374 92.7113ZM616.458 77.7951C624.696 77.7951 631.374 84.4733 631.374 92.7113L627.374 92.7113C627.374 86.6825 622.487 81.7951 616.458 81.7951L616.458 77.7951ZM441.574 66.8789C441.574 72.9078 446.461 77.7951 452.49 77.7951L452.49 81.7951C444.252 81.7951 437.574 75.1169 437.574 66.8789L441.574 66.8789Z" fill="#F9F9F9" /> <path id="Vector 332" d="M240.924 102.625C240.924 103.73 241.819 104.625 242.924 104.625C244.028 104.625 244.924 103.73 244.924 102.625L240.924 102.625ZM430.724 48.8479L430.725 66.8789L434.725 66.8789L434.724 48.8478L430.724 48.8479ZM419.808 77.7952L255.84 77.7952L255.84 81.7952L419.808 81.7952L419.808 77.7952ZM240.924 92.7113L240.924 102.625L244.924 102.625L244.924 92.7113L240.924 92.7113ZM255.84 77.7952C247.602 77.7952 240.924 84.4734 240.924 92.7113L244.924 92.7113C244.924 86.6825 249.811 81.7952 255.84 81.7952L255.84 77.7952ZM430.725 66.8789C430.725 72.9078 425.837 77.7952 419.808 77.7952L419.808 81.7952C428.046 81.7952 434.725 75.1169 434.725 66.8789L430.725 66.8789Z" fill="#F9F9F9" /> <path id="Vector 293" d="M435.987 60.7497L435.987 146.598" stroke="#F9F9F9" stroke-width="4" /> <path id="Vector 295" d="M342.684 253C342.684 251.895 341.788 251 340.684 251C339.579 251 338.684 251.895 338.684 253H342.684ZM92.295 146.598V464.04H96.295V146.598H92.295ZM134.295 506.04H323.684V502.04H134.295V506.04ZM342.684 487.04V253H338.684V487.04H342.684ZM323.684 506.04C334.177 506.04 342.684 497.534 342.684 487.04H338.684C338.684 495.324 331.968 502.04 323.684 502.04V506.04ZM92.295 464.04C92.295 487.236 111.099 506.04 134.295 506.04V502.04C113.308 502.04 96.295 485.027 96.295 464.04H92.295Z" fill="#F9F9F9" /> <path id="Vector 296" d="M342.684 485C342.684 483.895 341.788 483 340.684 483C339.579 483 338.684 483.895 338.684 485H342.684ZM44.4189 146.598V469H48.4189V146.598H44.4189ZM86.4189 511H323.684V507H86.4189V511ZM342.684 492V485H338.684V492H342.684ZM323.684 511C334.177 511 342.684 502.493 342.684 492H338.684C338.684 500.284 331.968 507 323.684 507V511ZM44.4189 469C44.4189 492.196 63.223 511 86.4189 511V507C65.4321 507 48.4189 489.987 48.4189 469H44.4189Z" fill="#F9F9F9" /> <path id="Vector 297" d="M441.111 531.619C441.111 532.724 440.215 533.619 439.111 533.619C438.006 533.619 437.111 532.724 437.111 531.619H441.111ZM777.781 430.012L777.781 474.81H773.781L773.781 430.012H777.781ZM735.781 516.81H455.921V512.81H735.781V516.81ZM455.921 516.81C447.741 516.81 441.111 523.44 441.111 531.619H437.111C437.111 521.231 445.532 512.81 455.921 512.81V516.81ZM777.781 474.81C777.781 498.006 758.977 516.81 735.781 516.81V512.81C756.768 512.81 773.781 495.796 773.781 474.81H777.781Z" fill="#F9F9F9" /> <path id="Vector 322" d="M441.111 524.54C441.111 525.645 440.215 526.54 439.111 526.54C438.006 526.54 437.111 525.645 437.111 524.54H441.111ZM727.275 430.012L727.275 485.902L723.275 485.902L723.275 430.012H727.275ZM702.275 510.902H454.75V506.902H702.275V510.902ZM454.75 510.902C447.217 510.902 441.111 517.008 441.111 524.54H437.111C437.111 514.799 445.008 506.902 454.75 506.902V510.902ZM727.275 485.902C727.275 499.709 716.082 510.902 702.275 510.902V506.902C713.873 506.902 723.275 497.5 723.275 485.902L727.275 485.902Z" fill="#F9F9F9" /> <path id="Vector 323" d="M441.111 517.804C441.111 518.908 440.215 519.804 439.111 519.804C438.006 519.804 437.111 518.908 437.111 517.804H441.111ZM633.377 430.012L633.377 480.28L629.377 480.28L629.377 430.012H633.377ZM608.377 505.28H453.635V501.28H608.377V505.28ZM453.635 505.28C446.718 505.28 441.111 510.887 441.111 517.804H437.111C437.111 508.678 444.509 501.28 453.635 501.28V505.28ZM633.377 480.28C633.377 494.087 622.184 505.28 608.377 505.28V501.28C619.975 501.28 629.377 491.877 629.377 480.28L633.377 480.28Z" fill="#F9F9F9" /> <path d="M630.923 380.565L678.548 380.565" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 321" d="M441.111 512.564C441.111 513.669 440.215 514.564 439.111 514.564C438.006 514.564 437.111 513.669 437.111 512.564H441.111ZM584.012 383.071V457.247H580.012V383.071H584.012ZM542.012 499.247H454.428V495.247H542.012V499.247ZM454.428 499.247C447.073 499.247 441.111 505.209 441.111 512.564H437.111C437.111 503 444.864 495.247 454.428 495.247V499.247ZM584.012 457.247C584.012 480.443 565.208 499.247 542.012 499.247V495.247C562.999 495.247 580.012 478.234 580.012 457.247H584.012Z" fill="#F9F9F9" /> <path id="Vector 301" d="M342.684 472.869C342.684 471.765 341.788 470.869 340.684 470.869C339.579 470.869 338.684 471.765 338.684 472.869H342.684ZM141.198 194.336V468.296H145.198V194.336H141.198ZM173.198 500.296H323.684V496.296H173.198V500.296ZM342.684 481.296V472.869H338.684V481.296H342.684ZM323.684 500.296C334.177 500.296 342.684 491.789 342.684 481.296H338.684C338.684 489.58 331.968 496.296 323.684 496.296V500.296ZM141.198 468.296C141.198 485.969 155.525 500.296 173.198 500.296V496.296C157.734 496.296 145.198 483.76 145.198 468.296H141.198Z" fill="#F9F9F9" /> <path id="Vector 303" d="M342.684 470.605C342.684 469.501 341.788 468.605 340.684 468.605C339.579 468.605 338.684 469.501 338.684 470.605H342.684ZM191.598 334.336V466.074H195.598V334.336H191.598ZM210.598 485.074H328.215V481.074H210.598V485.074ZM328.215 485.074C336.206 485.074 342.684 478.596 342.684 470.605H338.684C338.684 476.387 333.997 481.074 328.215 481.074V485.074ZM191.598 466.074C191.598 476.567 200.104 485.074 210.598 485.074V481.074C202.314 481.074 195.598 474.358 195.598 466.074H191.598Z" fill="#F9F9F9" /> <path id="Vector 305" d="M293.61 430.012H330.684C336.207 430.012 340.684 425.535 340.684 420.012V408.597" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="sf-zebra-line" d="M630.143 100.997L536.244 330.973C535.412 333.013 534.983 335.195 534.983 337.399V425.735" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 308" d="M536.002 429.81L483.737 429.81C474.349 429.81 466.737 422.199 466.737 412.81V163.598C466.737 154.21 459.126 146.598 449.737 146.598L437.198 146.598" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 309" d="M568.518 375.386L493.459 375.386C484.07 375.386 476.459 367.775 476.459 358.386V163.598C476.459 154.21 468.848 146.598 459.459 146.598L457.57 146.598" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 310" d="M767.043 284.268L551.494 284.268C542.106 284.268 534.494 276.657 534.494 267.268V166.598C534.494 155.553 525.54 146.598 514.494 146.598H459.183" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 311" d="M446.518 145.385H357.684C348.295 145.385 340.684 152.996 340.684 162.385V246.992" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 312" d="M767.045 287.746L545.869 287.746C540.034 287.746 534.607 284.754 531.493 279.82L511.614 248.325C507.951 242.52 501.566 239 494.701 239H346.742" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 317" d="M147.335 209V211C147.335 216.523 151.813 221 157.335 221H551C567.016 221 580 233.983 580 250L580 373.023" stroke="#F9F9F9" stroke-width="4" stroke-linejoin="round" /> <path id="Vector 230" d="M240.389 102.329L197.51 102.329C194.505 102.329 191.516 102.765 188.637 103.626L48.8447 145.385" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 229" d="M239.772 103.537C240.822 103.194 241.394 102.064 241.051 101.015C240.708 99.9647 239.578 99.3919 238.528 99.7353L239.772 103.537ZM238.528 99.7353L93.5993 147.129L94.8426 150.931L239.772 103.537L238.528 99.7353Z" fill="#F9F9F9" /> <path id="Vector 324" d="M240.564 103.05C241.345 102.269 241.345 101.003 240.564 100.222C239.783 99.4409 238.517 99.4409 237.736 100.222L240.564 103.05ZM237.736 100.222L142.948 195.01L145.776 197.838L240.564 103.05L237.736 100.222Z" fill="#F9F9F9" /> <path id="Vector 325" d="M242.488 101.324C242.695 100.239 241.983 99.1916 240.898 98.9848C239.813 98.7779 238.766 99.4899 238.559 100.575L242.488 101.324ZM238.559 100.575L193.913 334.796L197.842 335.545L242.488 101.324L238.559 100.575Z" fill="#F9F9F9" /> <path id="Vector 326" d="M242.524 100.949C242.524 99.8449 241.628 98.9494 240.524 98.9494C239.419 98.9494 238.524 99.8449 238.524 100.949L242.524 100.949ZM238.524 100.949L238.523 334.484L242.523 334.484L242.524 100.949L238.524 100.949Z" fill="#F9F9F9" /> <path id="Vector 227" d="M244.353 100.625C243.249 100.625 242.353 101.521 242.353 102.625C242.353 103.73 243.249 104.625 244.353 104.625V100.625ZM244.353 104.625H625.955V100.625H244.353V104.625Z" fill="#F9F9F9" /> <path id="Vector 238" d="M630.375 101.969L775.635 289.024" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 328" d="M630.375 101.969L727.551 334.781" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 330" d="M630.375 101.969V379.763" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 331" d="M630.375 101.969L581.749 379.763" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round" /> <path id="Vector 285" d="M633.341 427.447L681.22 380.268" stroke="#F9F9F9" stroke-width="4" /> <path id="Vector 286" d="M681.22 377.268L729.099 330.089" stroke="#F9F9F9" stroke-width="4" /> <path id="Vector 287" d="M776.663 428.448L727.873 333.966" stroke="#F9F9F9" stroke-width="4" /> <path id="Vector 288" d="M725.275 429.222L725.275 334.695" stroke="#F9F9F9" stroke-width="4" /> <path d="M288.594 427.847L264.559 264.398L264.398 263.629C261.384 249.277 248.725 239 234.059 239H158.156C149.872 239 143.156 232.284 143.156 224L143.156 199.832" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round"/> <path d="M46.4424 200.57L46.4424 209.837C46.4424 215.36 50.9195 219.837 56.4424 219.837L98.9666 219.837L133.198 219.837C138.721 219.837 143.198 215.36 143.198 209.837L143.198 198.232" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round"/> <path d="M94.3467 146.117H128.001C136.782 146.117 143.923 153.195 144 161.976L144.294 195.196" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round"/> <path d="M240.523 334.484L330.684 334.484C336.206 334.484 340.684 330.007 340.684 324.484V314" stroke="#F9F9F9" stroke-width="4" stroke-linecap="round"/> </g> <g class="al-2023-svg-milestones"> <g id="21-AI" data-milestone="svg-ai" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line" d="M435.521 143.586L435.521 541.645" stroke="url(#paint0_linear_42_3042)" stroke-width="1.51955" /> <path class="al-2023-connector-line reverse" id="connector-line_2" d="M427.611 541.645L427.611 438.916C427.611 431.783 421.829 426 414.695 426L387.433 426" stroke="url(#paint1_linear_42_3042)" stroke-width="1.5" stroke-linecap="round"/> <path class="al-2023-connector-line reverse" id="connector-line_3" d="M431.395 541.645L431.395 275.809C431.395 270.011 427.532 264.923 421.946 263.367L343.949 241.633" stroke="url(#paint2_linear_42_3042)" stroke-width="1.51955" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_4" d="M775.781 430.013L775.781 474.81C775.781 496.901 757.872 514.81 735.781 514.81H455.921C446.637 514.81 439.111 522.336 439.111 531.62V531.62" stroke="url(#paint3_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_5" d="M725.275 430.013L725.275 485.902C725.275 498.604 714.978 508.902 702.275 508.902H454.75C446.113 508.902 439.111 515.904 439.111 524.541V524.541" stroke="url(#paint4_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_6" d="M631.377 430.013L631.377 480.28C631.377 492.982 621.08 503.28 608.377 503.28H453.635C445.614 503.28 439.111 509.782 439.111 517.804V517.804" stroke="url(#paint5_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_7" d="M580 383.071V457.247C580 479.339 562.091 497.247 540 497.247H454.428C445.969 497.247 439.111 504.105 439.111 512.564V512.564" stroke="url(#paint6_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <g id="bottom-connectors"> <path class="al-2023-connector-line" id="connector-line_8" d="M425.452 589.284L425.452 647" stroke="#DD424C" stroke-width="1.5" /> <path class="al-2023-connector-line" id="connector-line_9" d="M432.452 589.284L432.452 647" stroke="#DD424C" stroke-width="1.5" /> <path class="al-2023-connector-line" id="connector-line_10" d="M439.452 589.284L439.452 647" stroke="#DD424C" stroke-width="1.5" /> <path class="al-2023-connector-line" id="connector-line_11" d="M446.452 589.284L446.452 647" stroke="#DD424C" stroke-width="1.5" /> <path class="al-2023-connector-line" id="connector-line_12" d="M453.452 589.284L453.452 647" stroke="#DD424C" stroke-width="1.5" /> <path class="al-2023-connector-line" id="connector-line_13" d="M460.452 589.284L460.452 647" stroke="#DD424C" stroke-width="1.5" /> <path class="al-2023-connector-line" id="connector-line_14" d="M418.452 589.284L418.452 647" stroke="#DD424C" stroke-width="1.5" /> <path class="al-2023-connector-line" id="connector-line_15" d="M411.452 589.284L411.452 647" stroke="#DD424C" stroke-width="1.5" /> </g> <g class="al-2023-active-dots"> <circle id="red-circle-glow2" cx="435.154" cy="568.574" r="44.1349" fill="#FF414B" fill-opacity="0.2" /> <circle class="no-stroke" id="red-circle-glow1" cx="435.154" cy="568.574" r="49.5678" fill="#FF414B" fill-opacity="0.2" /> </g> <circle class="al-2023-inactive-dot red" cx="435.154" cy="568.574" r="36.9543" fill="#FF414B" stroke="white" stroke-width="3" /> <g id="Union"> <path fill-rule="evenodd" clip-rule="evenodd" d="M432.487 573.997H439.515C439.782 573.999 440.046 573.948 440.292 573.848C440.539 573.747 440.763 573.599 440.952 573.411C441.141 573.223 441.291 573 441.394 572.754C441.496 572.508 441.549 572.244 441.549 571.978V564.95C441.549 564.684 441.496 564.42 441.394 564.174C441.291 563.928 441.141 563.705 440.952 563.517C440.763 563.33 440.539 563.181 440.292 563.081C440.046 562.98 439.782 562.929 439.515 562.931H432.487C431.952 562.931 431.438 563.144 431.06 563.522C430.681 563.901 430.468 564.415 430.468 564.95V571.978C430.468 572.514 430.681 573.027 431.06 573.406C431.438 573.785 431.952 573.997 432.487 573.997ZM432.076 564.539C432.185 564.429 432.333 564.368 432.487 564.368H439.515C439.668 564.37 439.815 564.432 439.922 564.541C440.03 564.65 440.09 564.797 440.09 564.95V571.978C440.09 572.131 440.03 572.278 439.922 572.387C439.815 572.496 439.668 572.558 439.515 572.56H432.487C432.333 572.56 432.185 572.499 432.076 572.39C431.967 572.28 431.905 572.132 431.905 571.978V564.95C431.905 564.796 431.967 564.648 432.076 564.539Z" fill="white" /> <path fill-rule="evenodd" clip-rule="evenodd" d="M429.297 548.665C429.156 548.612 429.02 548.543 428.893 548.459C428.567 548.242 428.313 547.934 428.162 547.572C428.012 547.211 427.972 546.813 428.048 546.429C428.124 546.045 428.313 545.692 428.589 545.415C428.866 545.139 429.219 544.95 429.603 544.874C429.987 544.798 430.385 544.838 430.746 544.988C431.108 545.139 431.416 545.393 431.633 545.719C431.849 546.045 431.964 546.429 431.963 546.82C431.963 547.342 431.755 547.843 431.386 548.212C431.198 548.4 430.976 548.546 430.734 548.644V550.586L434.198 553.223C434.308 553.308 434.397 553.417 434.459 553.541C434.522 553.666 434.555 553.802 434.557 553.941V560.114H436.627V555.447C436.492 555.395 436.363 555.328 436.241 555.247C435.914 555.029 435.66 554.718 435.511 554.355C435.361 553.991 435.324 553.592 435.403 553.207C435.482 552.822 435.674 552.469 435.954 552.194C436.235 551.918 436.591 551.733 436.977 551.661C437.363 551.589 437.762 551.634 438.123 551.79C438.484 551.946 438.79 552.206 439.002 552.537C439.214 552.868 439.323 553.254 439.314 553.647C439.305 554.163 439.093 554.654 438.725 555.016C438.534 555.204 438.309 555.348 438.064 555.444V560.114H439.81V552.928C439.814 552.806 439.843 552.685 439.895 552.574C439.947 552.463 440.021 552.363 440.112 552.281L444.202 548.502C444.196 548.49 444.191 548.477 444.185 548.465C444.036 548.105 443.997 547.709 444.073 547.327C444.149 546.945 444.337 546.594 444.612 546.319C444.888 546.044 445.238 545.856 445.62 545.78C446.002 545.704 446.398 545.743 446.758 545.892C447.118 546.041 447.425 546.293 447.642 546.617C447.858 546.941 447.973 547.322 447.973 547.711C447.973 548.233 447.766 548.734 447.397 549.103C447.027 549.473 446.527 549.68 446.004 549.68C445.733 549.68 445.465 549.624 445.218 549.516L441.254 553.18L441.248 560.114H441.685C442.391 560.116 443.067 560.398 443.566 560.897C443.998 561.331 444.266 561.897 444.329 562.5H447.183L448.972 560.114V557.945C448.841 557.893 448.715 557.828 448.597 557.749C448.273 557.532 448.02 557.225 447.871 556.865C447.722 556.505 447.683 556.109 447.759 555.727C447.835 555.345 448.023 554.995 448.298 554.719C448.574 554.444 448.924 554.256 449.306 554.18C449.688 554.104 450.084 554.143 450.444 554.292C450.804 554.441 451.111 554.694 451.328 555.018C451.544 555.341 451.659 555.722 451.659 556.112C451.659 556.634 451.452 557.135 451.083 557.504C450.889 557.697 450.659 557.847 450.409 557.945V560.294C450.409 560.491 450.343 560.683 450.222 560.84L448.174 563.578C448.087 563.689 447.976 563.779 447.849 563.842C447.722 563.904 447.583 563.936 447.442 563.937H444.344V565.288H450.596L452.752 562.32C452.834 562.206 452.942 562.112 453.067 562.048C453.191 561.983 453.33 561.948 453.47 561.946H455.97C456.069 561.695 456.219 561.465 456.411 561.273C456.687 560.997 457.037 560.81 457.419 560.734C457.801 560.658 458.197 560.697 458.557 560.846C458.917 560.995 459.224 561.247 459.441 561.571C459.657 561.895 459.772 562.276 459.772 562.665C459.772 562.924 459.722 563.18 459.623 563.418C459.524 563.657 459.379 563.874 459.196 564.057C459.013 564.24 458.796 564.385 458.557 564.484C458.318 564.583 458.062 564.634 457.804 564.634C457.414 564.634 457.033 564.518 456.71 564.302C456.386 564.086 456.133 563.778 455.984 563.418C455.98 563.407 455.975 563.395 455.97 563.383H453.722L451.566 566.351C451.482 566.466 451.373 566.559 451.247 566.624C451.121 566.689 450.982 566.723 450.84 566.725H444.344V568.795H449.108C449.206 568.543 449.356 568.314 449.549 568.121C449.824 567.846 450.175 567.658 450.557 567.582C450.939 567.506 451.335 567.545 451.694 567.694C452.054 567.843 452.362 568.095 452.578 568.419C452.794 568.743 452.91 569.124 452.91 569.513C452.91 570.035 452.702 570.536 452.333 570.905C451.964 571.275 451.463 571.482 450.941 571.482C450.552 571.482 450.171 571.367 449.847 571.15C449.523 570.934 449.271 570.626 449.122 570.267C449.117 570.255 449.112 570.243 449.108 570.232H444.344V572.33H451.358C451.48 572.33 451.601 572.355 451.714 572.403C451.826 572.451 451.927 572.522 452.012 572.611L455.745 576.471C455.88 576.41 456.022 576.364 456.169 576.335C456.551 576.259 456.947 576.298 457.307 576.447C457.667 576.596 457.974 576.848 458.19 577.172C458.407 577.496 458.522 577.876 458.522 578.266C458.522 578.788 458.315 579.289 457.946 579.658C457.576 580.027 457.075 580.235 456.553 580.235C456.164 580.235 455.783 580.119 455.459 579.903C455.136 579.687 454.883 579.379 454.734 579.019C454.585 578.66 454.546 578.264 454.622 577.882C454.649 577.747 454.69 577.616 454.743 577.491L451.135 573.768H444.344V574.148C444.344 574.854 444.064 575.531 443.566 576.031C443.067 576.531 442.391 576.812 441.685 576.814H441.254V578.819L442.929 580.371H445.492C445.586 580.182 445.711 580.007 445.862 579.856C446.138 579.58 446.489 579.393 446.871 579.317C447.253 579.241 447.648 579.28 448.008 579.429C448.368 579.578 448.675 579.83 448.892 580.154C449.108 580.478 449.224 580.859 449.224 581.248C449.224 581.77 449.016 582.271 448.647 582.64C448.278 583.01 447.777 583.217 447.255 583.217C446.865 583.217 446.485 583.101 446.161 582.885C445.837 582.669 445.585 582.361 445.436 582.001C445.411 581.943 445.39 581.883 445.372 581.823H442.713C442.483 581.823 442.263 581.735 442.095 581.579L440.112 579.739C440.019 579.653 439.944 579.548 439.894 579.432C439.843 579.316 439.817 579.19 439.817 579.063V576.814H438.675V582.139L441.606 584.295C441.718 584.379 441.809 584.487 441.873 584.612C441.936 584.736 441.97 584.874 441.973 585.013L441.967 587.385C441.978 587.389 441.99 587.394 442.001 587.398C442.36 587.547 442.668 587.8 442.884 588.123C443.101 588.447 443.216 588.828 443.216 589.217C443.216 589.739 443.009 590.24 442.639 590.609C442.27 590.979 441.769 591.186 441.247 591.186C440.858 591.186 440.477 591.071 440.153 590.854C439.829 590.638 439.577 590.331 439.428 589.971C439.279 589.611 439.24 589.215 439.316 588.833C439.392 588.451 439.58 588.1 439.855 587.825C440.048 587.632 440.277 587.483 440.529 587.384V585.33L437.597 583.109C437.486 583.024 437.397 582.916 437.334 582.791C437.272 582.667 437.239 582.53 437.237 582.391V576.814H434.694V580.665L434.707 580.67L434.729 580.679C435.088 580.828 435.396 581.081 435.612 581.404C435.829 581.728 435.944 582.109 435.944 582.498C435.944 583.02 435.737 583.521 435.367 583.891C434.998 584.26 434.497 584.467 433.975 584.467C433.586 584.467 433.205 584.352 432.881 584.135C432.557 583.919 432.305 583.612 432.156 583.252C432.007 582.892 431.968 582.496 432.044 582.114C432.12 581.732 432.308 581.381 432.583 581.106C432.776 580.913 433.005 580.764 433.256 580.665V576.814H431.611V583.109C431.613 583.247 431.584 583.383 431.526 583.508C431.467 583.632 431.381 583.742 431.273 583.828L427.212 587.143C427.331 587.4 427.393 587.681 427.393 587.967C427.393 588.226 427.342 588.483 427.242 588.722C427.143 588.961 426.997 589.179 426.814 589.362C426.63 589.545 426.412 589.69 426.172 589.788C425.933 589.887 425.676 589.937 425.417 589.936C425.028 589.935 424.648 589.818 424.325 589.601C424.002 589.383 423.751 589.075 423.603 588.716C423.455 588.356 423.417 587.96 423.494 587.578C423.57 587.197 423.759 586.847 424.034 586.572C424.31 586.298 424.661 586.111 425.042 586.035C425.418 585.961 425.807 585.998 426.162 586.142L430.174 582.872V576.81C429.52 576.773 428.9 576.497 428.434 576.031C427.935 575.532 427.653 574.855 427.651 574.148V572.481H425.603L423.807 574.982V577.934C423.819 577.939 423.83 577.944 423.842 577.948C424.201 578.097 424.509 578.35 424.725 578.674C424.942 578.997 425.057 579.378 425.057 579.768C425.057 580.29 424.85 580.791 424.48 581.16C424.111 581.529 423.61 581.736 423.088 581.736C422.699 581.736 422.318 581.621 421.994 581.405C421.671 581.188 421.418 580.881 421.269 580.521C421.12 580.161 421.081 579.765 421.157 579.383C421.233 579.001 421.421 578.651 421.696 578.375C421.889 578.183 422.118 578.033 422.37 577.934V574.831C422.37 574.641 422.428 574.456 422.535 574.299L424.597 571.425C424.679 571.31 424.787 571.215 424.912 571.149C425.036 571.083 425.175 571.047 425.316 571.044H427.651V570.232H421.802L419.991 573.006C419.913 573.127 419.807 573.227 419.682 573.298C419.557 573.369 419.416 573.41 419.272 573.415H417.067C416.969 573.665 416.82 573.895 416.626 574.089C416.257 574.458 415.756 574.666 415.234 574.666C414.845 574.666 414.464 574.55 414.14 574.334C413.816 574.118 413.564 573.81 413.415 573.45C413.266 573.09 413.227 572.695 413.303 572.313C413.379 571.931 413.566 571.58 413.842 571.304C414.117 571.029 414.468 570.842 414.85 570.766C415.232 570.69 415.628 570.729 415.987 570.878C416.347 571.027 416.655 571.279 416.871 571.603C416.95 571.721 417.016 571.847 417.067 571.978H418.949L420.753 569.211C420.835 569.083 420.949 568.977 421.083 568.904C421.218 568.831 421.369 568.794 421.522 568.795H427.651V566.725H423.942C423.844 566.924 423.713 567.105 423.555 567.261C423.369 567.443 423.149 567.587 422.907 567.684C422.666 567.781 422.407 567.828 422.147 567.825C421.758 567.819 421.38 567.699 421.06 567.478C420.74 567.258 420.492 566.948 420.348 566.588C420.203 566.227 420.169 565.832 420.248 565.452C420.328 565.071 420.519 564.723 420.796 564.451C421.073 564.179 421.425 563.995 421.806 563.922C422.188 563.849 422.582 563.891 422.94 564.042C423.298 564.193 423.604 564.446 423.818 564.77C423.924 564.931 424.006 565.106 424.061 565.288H427.651V563.384H421.342C421.205 563.386 421.069 563.358 420.945 563.3C420.821 563.243 420.711 563.159 420.623 563.053L417.271 559.009C417.025 559.116 416.757 559.173 416.484 559.173C416.093 559.173 415.711 559.056 415.387 558.838C415.062 558.62 414.81 558.311 414.662 557.949C414.514 557.587 414.477 557.189 414.556 556.806C414.635 556.423 414.826 556.073 415.105 555.799C415.384 555.525 415.738 555.34 416.123 555.268C416.507 555.197 416.904 555.241 417.263 555.395C417.622 555.55 417.927 555.808 418.139 556.136C418.351 556.465 418.46 556.849 418.453 557.24C418.449 557.5 418.393 557.753 418.291 557.987L421.558 561.946H427.787C427.917 561.555 428.137 561.194 428.434 560.897C428.9 560.431 429.52 560.155 430.174 560.118V557.635L427.982 555.58H425.259L425.252 555.598L425.245 555.615C425.146 555.854 425.001 556.071 424.818 556.254C424.636 556.436 424.418 556.581 424.18 556.68C423.941 556.779 423.685 556.83 423.426 556.83C423.037 556.83 422.656 556.715 422.332 556.498C422.008 556.282 421.756 555.975 421.607 555.615C421.458 555.255 421.419 554.859 421.495 554.477C421.571 554.095 421.758 553.744 422.034 553.469C422.309 553.194 422.66 553.006 423.042 552.93C423.424 552.854 423.82 552.893 424.18 553.042C424.539 553.191 424.847 553.444 425.063 553.767C425.142 553.886 425.208 554.011 425.259 554.143H428.183C428.415 554.142 428.639 554.229 428.808 554.387L431.323 556.744C431.414 556.83 431.485 556.934 431.535 557.049C431.584 557.164 431.61 557.287 431.611 557.412V560.114H433.12V554.179L429.656 551.548C429.546 551.463 429.457 551.355 429.395 551.23C429.333 551.106 429.299 550.969 429.297 550.83V548.665ZM429.693 546.368C429.782 546.31 429.887 546.28 429.994 546.281C430.136 546.283 430.271 546.341 430.37 546.441C430.47 546.542 430.526 546.678 430.526 546.82C430.526 546.927 430.494 547.031 430.434 547.12C430.375 547.209 430.29 547.278 430.191 547.319C430.092 547.359 429.984 547.369 429.879 547.348C429.774 547.327 429.678 547.275 429.603 547.198C429.528 547.122 429.477 547.026 429.457 546.921C429.437 546.816 429.449 546.707 429.491 546.609C429.533 546.51 429.603 546.427 429.693 546.368ZM437.044 553.159C437.133 553.101 437.238 553.071 437.345 553.072C437.487 553.074 437.622 553.132 437.722 553.232C437.821 553.333 437.877 553.469 437.877 553.611C437.877 553.718 437.845 553.822 437.786 553.911C437.726 554 437.642 554.069 437.543 554.11C437.444 554.15 437.335 554.16 437.23 554.139C437.126 554.118 437.03 554.066 436.954 553.989C436.879 553.913 436.829 553.817 436.809 553.712C436.789 553.607 436.8 553.498 436.842 553.4C436.884 553.301 436.954 553.218 437.044 553.159ZM445.709 547.269C445.796 547.211 445.899 547.179 446.004 547.179C446.146 547.179 446.281 547.235 446.38 547.335C446.48 547.435 446.536 547.57 446.536 547.711C446.536 547.816 446.505 547.919 446.447 548.007C446.388 548.094 446.305 548.162 446.208 548.202C446.111 548.243 446.004 548.253 445.901 548.233C445.798 548.212 445.703 548.162 445.628 548.087C445.554 548.013 445.503 547.918 445.483 547.815C445.462 547.712 445.473 547.605 445.513 547.508C445.553 547.41 445.622 547.327 445.709 547.269ZM423.131 554.419C423.218 554.361 423.321 554.33 423.426 554.33V554.365C423.561 554.365 423.691 554.416 423.79 554.508C423.889 554.6 423.949 554.727 423.958 554.861C423.958 554.966 423.927 555.069 423.868 555.157C423.81 555.244 423.727 555.312 423.63 555.353C423.532 555.393 423.426 555.403 423.322 555.383C423.219 555.362 423.124 555.312 423.05 555.237C422.976 555.163 422.925 555.068 422.905 554.965C422.884 554.862 422.895 554.755 422.935 554.658C422.975 554.561 423.043 554.478 423.131 554.419ZM416.189 556.762C416.276 556.703 416.379 556.672 416.484 556.672C416.554 556.672 416.623 556.686 416.688 556.713C416.752 556.739 416.811 556.778 416.86 556.828C416.91 556.877 416.949 556.936 416.976 557C417.002 557.065 417.016 557.134 417.016 557.204C417.016 557.309 416.985 557.412 416.927 557.499C416.868 557.587 416.785 557.655 416.688 557.695C416.591 557.735 416.484 557.746 416.381 557.725C416.277 557.705 416.183 557.654 416.108 557.58C416.034 557.505 415.983 557.411 415.963 557.308C415.942 557.204 415.953 557.097 415.993 557C416.033 556.903 416.101 556.82 416.189 556.762ZM421.851 565.414C421.939 565.355 422.041 565.324 422.147 565.324C422.288 565.324 422.423 565.38 422.523 565.48C422.622 565.579 422.678 565.715 422.678 565.856C422.678 565.961 422.647 566.064 422.589 566.151C422.53 566.239 422.447 566.307 422.35 566.347C422.253 566.387 422.146 566.398 422.043 566.377C421.94 566.357 421.845 566.306 421.771 566.232C421.696 566.157 421.646 566.063 421.625 565.959C421.605 565.856 421.615 565.749 421.655 565.652C421.696 565.555 421.764 565.472 421.851 565.414ZM414.939 572.255C415.026 572.196 415.129 572.165 415.234 572.165C415.375 572.165 415.51 572.221 415.61 572.321C415.71 572.42 415.766 572.556 415.766 572.697C415.766 572.802 415.735 572.905 415.676 572.992C415.618 573.08 415.535 573.148 415.437 573.188C415.34 573.228 415.233 573.239 415.13 573.218C415.027 573.198 414.932 573.147 414.858 573.073C414.784 572.998 414.733 572.904 414.712 572.8C414.692 572.697 414.702 572.59 414.743 572.493C414.783 572.396 414.851 572.313 414.939 572.255ZM422.793 579.325C422.88 579.267 422.983 579.236 423.088 579.236C423.229 579.236 423.364 579.292 423.464 579.392C423.564 579.491 423.62 579.626 423.62 579.768C423.62 579.873 423.589 579.976 423.53 580.063C423.472 580.15 423.389 580.219 423.292 580.259C423.195 580.299 423.088 580.31 422.984 580.289C422.881 580.269 422.787 580.218 422.712 580.144C422.638 580.069 422.587 579.974 422.567 579.871C422.546 579.768 422.557 579.661 422.597 579.564C422.637 579.467 422.705 579.384 422.793 579.325ZM425.123 587.528C425.21 587.469 425.312 587.437 425.417 587.435V587.421C425.488 587.421 425.559 587.435 425.625 587.463C425.69 587.49 425.75 587.53 425.8 587.581C425.851 587.632 425.89 587.692 425.917 587.759C425.943 587.825 425.957 587.896 425.956 587.967C425.956 588.072 425.925 588.174 425.867 588.262C425.808 588.349 425.726 588.417 425.629 588.458C425.532 588.498 425.426 588.509 425.323 588.489C425.22 588.469 425.125 588.419 425.05 588.345C424.976 588.272 424.925 588.178 424.903 588.075C424.882 587.972 424.891 587.866 424.931 587.768C424.97 587.671 425.037 587.588 425.123 587.528ZM433.68 582.056C433.767 581.998 433.87 581.966 433.975 581.966C434.116 581.966 434.251 582.023 434.351 582.122C434.451 582.222 434.507 582.357 434.507 582.498C434.507 582.603 434.476 582.706 434.417 582.794C434.359 582.881 434.276 582.949 434.179 582.99C434.082 583.03 433.975 583.04 433.871 583.02C433.768 582.999 433.674 582.949 433.599 582.874C433.525 582.8 433.474 582.705 433.454 582.602C433.433 582.499 433.444 582.392 433.484 582.295C433.524 582.198 433.592 582.115 433.68 582.056ZM440.952 588.775C441.039 588.717 441.142 588.685 441.247 588.685C441.388 588.685 441.523 588.742 441.623 588.841C441.723 588.941 441.779 589.076 441.779 589.217C441.779 589.322 441.748 589.425 441.689 589.513C441.631 589.6 441.548 589.668 441.451 589.709C441.353 589.749 441.247 589.759 441.143 589.739C441.04 589.718 440.946 589.668 440.871 589.593C440.797 589.519 440.746 589.424 440.726 589.321C440.705 589.218 440.716 589.111 440.756 589.014C440.796 588.917 440.864 588.834 440.952 588.775ZM446.959 580.806C447.047 580.747 447.15 580.716 447.255 580.716C447.396 580.716 447.531 580.772 447.631 580.872C447.73 580.972 447.786 581.107 447.786 581.248C447.786 581.353 447.755 581.456 447.697 581.543C447.638 581.631 447.555 581.699 447.458 581.739C447.361 581.78 447.254 581.79 447.151 581.77C447.048 581.749 446.953 581.698 446.879 581.624C446.804 581.55 446.754 581.455 446.733 581.352C446.713 581.249 446.723 581.142 446.763 581.045C446.804 580.947 446.872 580.864 446.959 580.806ZM449.395 555.669C449.483 555.611 449.585 555.58 449.691 555.58C449.76 555.58 449.829 555.594 449.894 555.62C449.959 555.647 450.017 555.686 450.067 555.736C450.116 555.785 450.155 555.844 450.182 555.908C450.209 555.973 450.222 556.042 450.222 556.112C450.222 556.217 450.191 556.32 450.133 556.407C450.074 556.494 449.991 556.563 449.894 556.603C449.797 556.643 449.69 556.654 449.587 556.633C449.484 556.613 449.389 556.562 449.314 556.488C449.24 556.413 449.189 556.318 449.169 556.215C449.148 556.112 449.159 556.005 449.199 555.908C449.239 555.811 449.308 555.728 449.395 555.669ZM457.508 562.223C457.596 562.164 457.698 562.133 457.804 562.133C457.873 562.133 457.943 562.147 458.007 562.174C458.072 562.2 458.13 562.24 458.18 562.289C458.229 562.338 458.268 562.397 458.295 562.461C458.322 562.526 458.335 562.595 458.335 562.665C458.335 562.77 458.304 562.873 458.246 562.96C458.187 563.048 458.104 563.116 458.007 563.156C457.91 563.197 457.803 563.207 457.7 563.187C457.597 563.166 457.502 563.115 457.428 563.041C457.353 562.967 457.303 562.872 457.282 562.769C457.261 562.666 457.272 562.559 457.312 562.461C457.353 562.364 457.421 562.281 457.508 562.223ZM450.646 569.071C450.733 569.013 450.836 568.981 450.941 568.981C451.082 568.981 451.217 569.037 451.317 569.137C451.417 569.237 451.473 569.372 451.473 569.513C451.473 569.618 451.442 569.721 451.383 569.809C451.325 569.896 451.242 569.964 451.144 570.004C451.047 570.045 450.94 570.055 450.837 570.035C450.734 570.014 450.639 569.964 450.565 569.889C450.491 569.815 450.44 569.72 450.419 569.617C450.399 569.514 450.409 569.407 450.45 569.31C450.49 569.212 450.558 569.129 450.646 569.071ZM456.258 577.824C456.345 577.765 456.448 577.734 456.553 577.734V577.72C456.624 577.72 456.695 577.734 456.76 577.761C456.826 577.789 456.885 577.83 456.934 577.88C456.984 577.931 457.023 577.992 457.049 578.058C457.075 578.124 457.087 578.195 457.085 578.266C457.085 578.371 457.054 578.474 456.995 578.561C456.937 578.649 456.854 578.717 456.757 578.757C456.66 578.797 456.553 578.808 456.45 578.787C456.346 578.767 456.252 578.716 456.177 578.642C456.103 578.567 456.052 578.473 456.032 578.37C456.011 578.266 456.022 578.159 456.062 578.062C456.102 577.965 456.17 577.882 456.258 577.824ZM430.317 561.551C429.992 561.553 429.68 561.683 429.45 561.913C429.22 562.143 429.09 562.455 429.088 562.78V574.148C429.09 574.473 429.22 574.785 429.45 575.015C429.68 575.245 429.992 575.375 430.317 575.377H441.685C442.01 575.375 442.321 575.245 442.55 575.015C442.779 574.784 442.907 574.473 442.907 574.148V562.78C442.907 562.455 442.779 562.144 442.55 561.914C442.321 561.683 442.01 561.553 441.685 561.551H430.317Z" fill="white" /> </g> </g> <g id="20-CELLxGENE-Census" data-milestone="svg-cellxgene-census" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_16" d="M388.307 428L388.307 308.456C388.307 305.694 387.421 303.004 385.78 300.782L345.98 246.901" stroke="#4BC1C0" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M360.778 456.488C358.512 456.488 357.06 454.937 357.06 452.484C357.06 450.031 358.512 448.48 360.778 448.48C362.395 448.48 363.616 449.261 364.177 450.724L362.912 451.219C362.571 450.262 361.823 449.789 360.778 449.789C359.293 449.789 358.435 450.757 358.435 452.473C358.435 454.2 359.304 455.179 360.778 455.179C361.834 455.179 362.582 454.684 362.912 453.716L364.199 454.2C363.649 455.685 362.417 456.488 360.778 456.488ZM365.408 456.323V448.656H370.512V449.921H366.783V451.747H370.248V453.012H366.783V455.058H370.512V456.323H365.408ZM372.122 456.323V448.656H373.497V455.058H376.775V456.323H372.122ZM377.837 456.323V448.656H379.212V455.058H382.49V456.323H377.837ZM382.617 456.323L384.476 453.595L382.617 450.9H384.234L385.356 452.693L386.478 450.9H388.095L386.225 453.595L388.095 456.323H386.478L385.356 454.497L384.234 456.323H382.617ZM392.648 452.176H395.728V456.323H394.749L394.584 455.531C394.133 456.147 393.308 456.488 392.318 456.488C390.173 456.488 388.534 454.904 388.534 452.473C388.534 450.196 389.975 448.48 392.274 448.48C393.836 448.48 395.09 449.272 395.651 450.724L394.386 451.219C394.045 450.273 393.286 449.789 392.252 449.789C390.778 449.789 389.909 450.779 389.909 452.462C389.909 454.211 390.844 455.179 392.406 455.179C393.638 455.179 394.364 454.574 394.364 453.54V453.441H392.648V452.176ZM397.377 456.323V448.656H402.481V449.921H398.752V451.747H402.217V453.012H398.752V455.058H402.481V456.323H397.377ZM408.733 448.656H410.108V456.323H408.678L405.466 451.021V456.323H404.091V448.656H405.51L408.733 453.936V448.656ZM412.04 456.323V448.656H417.144V449.921H413.415V451.747H416.88V453.012H413.415V455.058H417.144V456.323H412.04ZM374.828 469.488C372.562 469.488 371.11 467.937 371.11 465.484C371.11 463.031 372.562 461.48 374.828 461.48C376.445 461.48 377.666 462.261 378.227 463.724L376.962 464.219C376.621 463.262 375.873 462.789 374.828 462.789C373.343 462.789 372.485 463.757 372.485 465.473C372.485 467.2 373.354 468.179 374.828 468.179C375.884 468.179 376.632 467.684 376.962 466.716L378.249 467.2C377.699 468.685 376.467 469.488 374.828 469.488ZM383.699 466.54C383.699 466.705 383.688 466.87 383.666 467.046H379.948C380.003 467.761 380.443 468.234 381.301 468.234C381.785 468.234 382.225 468.08 382.599 467.651L383.512 468.454C382.918 469.114 382.203 469.433 381.29 469.433C379.42 469.433 378.628 468.091 378.628 466.639C378.628 465.22 379.398 463.79 381.202 463.79C382.885 463.79 383.699 465.033 383.699 466.54ZM379.937 466.001H382.434C382.412 465.308 381.884 464.89 381.191 464.89C380.388 464.89 380.014 465.462 379.937 466.001ZM387.742 463.79C388.963 463.79 389.656 464.538 389.656 465.825V469.323H388.336V466.155C388.336 465.781 388.336 464.945 387.335 464.945C386.103 464.945 386.103 466.188 386.103 467.156V469.323H384.783V463.9H386.103V464.527C386.488 464.01 387.082 463.79 387.742 463.79ZM392.783 469.433C391.639 469.433 390.77 468.74 390.506 467.915L391.562 467.442C391.705 467.838 391.991 468.333 392.717 468.333C393.333 468.333 393.597 467.981 393.597 467.695C393.597 466.782 390.803 467.387 390.803 465.374C390.803 464.329 391.749 463.79 392.794 463.79C393.729 463.79 394.444 464.23 394.851 464.967L393.828 465.528C393.641 465.187 393.344 464.835 392.75 464.835C392.321 464.835 392.057 465.044 392.057 465.297C392.057 466.122 394.895 465.638 394.895 467.618C394.895 468.883 393.806 469.433 392.783 469.433ZM399.386 463.9H400.706V469.323H399.386V468.696C399.001 469.213 398.407 469.433 397.769 469.433C396.405 469.433 395.833 468.443 395.833 467.288V463.9H397.153V466.958C397.153 467.332 397.153 468.278 398.154 468.278C399.386 468.278 399.386 466.925 399.386 465.957V463.9ZM403.954 469.433C402.81 469.433 401.941 468.74 401.677 467.915L402.733 467.442C402.876 467.838 403.162 468.333 403.888 468.333C404.504 468.333 404.768 467.981 404.768 467.695C404.768 466.782 401.974 467.387 401.974 465.374C401.974 464.329 402.92 463.79 403.965 463.79C404.9 463.79 405.615 464.23 406.022 464.967L404.999 465.528C404.812 465.187 404.515 464.835 403.921 464.835C403.492 464.835 403.228 465.044 403.228 465.297C403.228 466.122 406.066 465.638 406.066 467.618C406.066 468.883 404.977 469.433 403.954 469.433Z" fill="black" /> <g class="al-2023-active-dots turqiose" id="active dots"> <circle id="Ellipse 2765" cx="388.737" cy="427.276" r="48.5676" fill="#74FFFE" fill-opacity="0.1" /> <circle id="Ellipse 2767" cx="388.738" cy="427.276" r="25.309" fill="#74FFFE" fill-opacity="0.4" /> <circle id="Ellipse 2771" cx="388.738" cy="427.276" r="13.0446" fill="white" stroke="#73DAD9" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot turqiose" id="inactive dot" cx="388.737" cy="427.276" r="10.2374" fill="#73DAD9" stroke="white" stroke-width="3" /> <circle class="overlay-dot turqiose" id="inactive dot" cx="388.737" cy="427.276" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="19-Human-Breast-Cell-Atlas" data-milestone="human-breast-cell-atlas" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" d="M293.61 430.013H330.684C336.207 430.013 340.684 425.535 340.684 420.013V419.688" stroke="url(#paint7_linear_42_3042)" stroke-width="1.5" stroke-linecap="round"/> <path class="al-2023-connector-line reverse" d="M288.594 427.847L264.559 264.398L264.398 263.629C261.384 249.277 248.725 239 234.059 239H158.156C149.872 239 143.156 232.284 143.156 224L143.156 199.832" stroke="#22704F" stroke-width="1.5" stroke-linecap="round"/> <path class="al-2023-svg-text" d="M201.203 418.333H202.578V421.424H205.933V418.333H207.308V426H205.933V422.689H202.578V426H201.203V418.333ZM213.792 420.577V426H212.472V425.373C212.288 425.622 212.054 425.809 211.768 425.934C211.489 426.051 211.185 426.11 210.855 426.11C210.209 426.11 209.725 425.908 209.403 425.505C209.08 425.102 208.919 424.588 208.919 423.965V420.577H210.239V423.635C210.239 423.98 210.297 424.288 210.415 424.559C210.532 424.823 210.807 424.955 211.24 424.955C211.621 424.955 211.9 424.838 212.076 424.603C212.259 424.368 212.369 424.097 212.406 423.789C212.45 423.481 212.472 423.096 212.472 422.634V420.577H213.792ZM221.396 420.467C222.012 420.467 222.481 420.669 222.804 421.072C223.127 421.468 223.288 421.959 223.288 422.546V426H221.968V422.942C221.968 422.062 221.66 421.622 221.044 421.622C220.699 421.622 220.45 421.732 220.296 421.952C220.142 422.165 220.05 422.418 220.021 422.711C219.992 422.997 219.977 423.404 219.977 423.932V426H218.657V422.942C218.657 422.062 218.353 421.622 217.744 421.622C217.399 421.622 217.15 421.732 216.996 421.952C216.842 422.165 216.747 422.421 216.71 422.722C216.681 423.015 216.666 423.419 216.666 423.932V426H215.346L215.335 420.577H216.611V421.259C216.919 420.731 217.403 420.467 218.063 420.467C218.4 420.467 218.708 420.548 218.987 420.709C219.273 420.87 219.493 421.145 219.647 421.534C219.845 421.153 220.091 420.881 220.384 420.72C220.677 420.551 221.015 420.467 221.396 420.467ZM226.792 420.467C227.511 420.467 228.076 420.658 228.486 421.039C228.904 421.413 229.113 421.926 229.113 422.579V426H227.903L227.793 425.296C227.632 425.553 227.405 425.754 227.111 425.901C226.825 426.04 226.503 426.11 226.143 426.11C225.769 426.11 225.432 426.037 225.131 425.89C224.838 425.736 224.607 425.523 224.438 425.252C224.27 424.981 224.185 424.676 224.185 424.339C224.185 424.016 224.255 423.738 224.394 423.503C224.534 423.268 224.735 423.092 224.999 422.975C225.351 422.814 225.832 422.733 226.44 422.733H227.793V422.579C227.793 422.286 227.702 422.055 227.518 421.886C227.335 421.71 227.086 421.622 226.77 421.622C226.492 421.622 226.228 421.692 225.978 421.831C225.729 421.97 225.505 422.172 225.307 422.436L224.35 421.633C224.996 420.856 225.81 420.467 226.792 420.467ZM226.352 424.988C226.748 424.988 227.086 424.867 227.364 424.625C227.65 424.376 227.793 424.075 227.793 423.723H226.616C226.191 423.723 225.894 423.785 225.725 423.91C225.579 424.013 225.505 424.163 225.505 424.361C225.505 424.552 225.579 424.706 225.725 424.823C225.879 424.933 226.088 424.988 226.352 424.988ZM233.462 420.467C234.071 420.467 234.54 420.647 234.87 421.006C235.207 421.358 235.376 421.857 235.376 422.502V426H234.056V422.832C234.056 422.502 233.997 422.22 233.88 421.985C233.763 421.743 233.488 421.622 233.055 421.622C232.674 421.622 232.391 421.732 232.208 421.952C232.032 422.165 231.922 422.421 231.878 422.722C231.841 423.015 231.823 423.386 231.823 423.833V426H230.503V420.577H231.823V421.204C232.006 420.955 232.237 420.771 232.516 420.654C232.802 420.529 233.117 420.467 233.462 420.467ZM239.671 418.333H242.344C243.106 418.333 243.7 418.505 244.126 418.85C244.558 419.187 244.775 419.66 244.775 420.269C244.775 420.628 244.701 420.947 244.555 421.226C244.408 421.497 244.199 421.71 243.928 421.864C244.764 422.165 245.182 422.795 245.182 423.756C245.182 424.46 244.962 425.01 244.522 425.406C244.082 425.802 243.469 426 242.685 426H239.671V418.333ZM242.344 421.38C242.688 421.38 242.949 421.307 243.125 421.16C243.308 421.013 243.4 420.797 243.4 420.511C243.4 420.218 243.308 419.994 243.125 419.84C242.941 419.679 242.681 419.598 242.344 419.598H241.046V421.38H242.344ZM242.575 424.735C242.956 424.735 243.257 424.64 243.477 424.449C243.697 424.251 243.807 423.983 243.807 423.646C243.807 423.323 243.7 423.078 243.488 422.909C243.282 422.733 242.978 422.645 242.575 422.645H241.046V424.735H242.575ZM249.152 420.467C249.511 420.467 249.856 420.57 250.186 420.775L249.548 421.941C249.357 421.816 249.137 421.754 248.888 421.754C248.089 421.754 247.689 422.26 247.689 423.272V426H246.369V420.577H247.7V421.501C247.81 421.178 247.997 420.925 248.261 420.742C248.532 420.559 248.829 420.467 249.152 420.467ZM255.2 423.217C255.2 423.378 255.189 423.547 255.167 423.723H251.449C251.478 424.09 251.607 424.379 251.834 424.592C252.061 424.805 252.384 424.911 252.802 424.911C253.33 424.911 253.763 424.717 254.1 424.328L255.013 425.131C254.712 425.461 254.379 425.707 254.012 425.868C253.653 426.029 253.246 426.11 252.791 426.11C252.197 426.11 251.698 425.982 251.295 425.725C250.899 425.468 250.606 425.131 250.415 424.713C250.224 424.288 250.129 423.822 250.129 423.316C250.129 422.817 250.221 422.352 250.404 421.919C250.595 421.486 250.881 421.138 251.262 420.874C251.651 420.603 252.131 420.467 252.703 420.467C253.246 420.467 253.704 420.588 254.078 420.83C254.452 421.072 254.731 421.402 254.914 421.82C255.105 422.238 255.2 422.704 255.2 423.217ZM253.935 422.678C253.928 422.341 253.807 422.073 253.572 421.875C253.337 421.67 253.044 421.567 252.692 421.567C252.318 421.567 252.025 421.677 251.812 421.897C251.607 422.11 251.482 422.37 251.438 422.678H253.935ZM258.385 420.467C259.104 420.467 259.668 420.658 260.079 421.039C260.497 421.413 260.706 421.926 260.706 422.579V426H259.496L259.386 425.296C259.225 425.553 258.997 425.754 258.704 425.901C258.418 426.04 258.095 426.11 257.736 426.11C257.362 426.11 257.025 426.037 256.724 425.89C256.431 425.736 256.2 425.523 256.031 425.252C255.862 424.981 255.778 424.676 255.778 424.339C255.778 424.016 255.848 423.738 255.987 423.503C256.126 423.268 256.328 423.092 256.592 422.975C256.944 422.814 257.424 422.733 258.033 422.733H259.386V422.579C259.386 422.286 259.294 422.055 259.111 421.886C258.928 421.71 258.678 421.622 258.363 421.622C258.084 421.622 257.82 421.692 257.571 421.831C257.322 421.97 257.098 422.172 256.9 422.436L255.943 421.633C256.588 420.856 257.402 420.467 258.385 420.467ZM257.945 424.988C258.341 424.988 258.678 424.867 258.957 424.625C259.243 424.376 259.386 424.075 259.386 423.723H258.209C257.784 423.723 257.487 423.785 257.318 423.91C257.171 424.013 257.098 424.163 257.098 424.361C257.098 424.552 257.171 424.706 257.318 424.823C257.472 424.933 257.681 424.988 257.945 424.988ZM263.801 426.11C263.251 426.11 262.767 425.967 262.349 425.681C261.938 425.388 261.663 425.025 261.524 424.592L262.58 424.119C262.792 424.713 263.177 425.01 263.735 425.01C264.021 425.01 264.237 424.944 264.384 424.812C264.538 424.68 264.615 424.533 264.615 424.372C264.615 424.211 264.538 424.09 264.384 424.009C264.23 423.928 263.977 423.837 263.625 423.734C263.258 423.639 262.954 423.54 262.712 423.437C262.47 423.327 262.261 423.162 262.085 422.942C261.909 422.715 261.821 422.418 261.821 422.051C261.821 421.552 262.011 421.164 262.393 420.885C262.781 420.606 263.254 420.467 263.812 420.467C264.274 420.467 264.681 420.57 265.033 420.775C265.385 420.98 265.663 421.27 265.869 421.644L264.846 422.205C264.736 422 264.596 421.835 264.428 421.71C264.259 421.578 264.039 421.512 263.768 421.512C263.562 421.512 263.394 421.556 263.262 421.644C263.137 421.732 263.075 421.842 263.075 421.974C263.075 422.121 263.152 422.234 263.306 422.315C263.467 422.396 263.713 422.48 264.043 422.568C264.424 422.678 264.739 422.788 264.989 422.898C265.238 423.008 265.454 423.177 265.638 423.404C265.821 423.631 265.913 423.928 265.913 424.295C265.913 424.698 265.81 425.036 265.605 425.307C265.407 425.578 265.146 425.78 264.824 425.912C264.501 426.044 264.16 426.11 263.801 426.11ZM268.566 421.622V424.383C268.566 424.596 268.625 424.753 268.742 424.856C268.867 424.959 269.039 425.01 269.259 425.01C269.443 425.01 269.663 424.97 269.919 424.889V425.945C269.589 426.055 269.259 426.11 268.929 426.11C268.438 426.11 268.035 425.978 267.719 425.714C267.404 425.443 267.246 425.032 267.246 424.482V421.622H266.366V420.577H267.246V419.312L268.566 418.333V420.577H269.919V421.622H268.566ZM227.735 438.165C226.987 438.165 226.331 438.004 225.766 437.681C225.209 437.351 224.776 436.885 224.468 436.284C224.167 435.675 224.017 434.968 224.017 434.161C224.017 433.354 224.167 432.65 224.468 432.049C224.776 431.44 225.209 430.975 225.766 430.652C226.331 430.322 226.987 430.157 227.735 430.157C228.549 430.157 229.249 430.351 229.836 430.74C230.423 431.121 230.855 431.675 231.134 432.401L229.869 432.896C229.7 432.419 229.433 432.064 229.066 431.829C228.707 431.587 228.263 431.466 227.735 431.466C226.994 431.466 226.419 431.701 226.008 432.17C225.597 432.632 225.392 433.292 225.392 434.15C225.392 435.008 225.597 435.675 226.008 436.152C226.419 436.621 226.994 436.856 227.735 436.856C228.263 436.856 228.71 436.735 229.077 436.493C229.444 436.244 229.708 435.877 229.869 435.393L231.156 435.877C230.885 436.618 230.452 437.186 229.858 437.582C229.264 437.971 228.556 438.165 227.735 438.165ZM236.605 435.217C236.605 435.378 236.594 435.547 236.572 435.723H232.854C232.884 436.09 233.012 436.379 233.239 436.592C233.467 436.805 233.789 436.911 234.207 436.911C234.735 436.911 235.168 436.717 235.505 436.328L236.418 437.131C236.118 437.461 235.784 437.707 235.417 437.868C235.058 438.029 234.651 438.11 234.196 438.11C233.602 438.11 233.104 437.982 232.7 437.725C232.304 437.468 232.011 437.131 231.82 436.713C231.63 436.288 231.534 435.822 231.534 435.316C231.534 434.817 231.626 434.352 231.809 433.919C232 433.486 232.286 433.138 232.667 432.874C233.056 432.603 233.536 432.467 234.108 432.467C234.651 432.467 235.109 432.588 235.483 432.83C235.857 433.072 236.136 433.402 236.319 433.82C236.51 434.238 236.605 434.704 236.605 435.217ZM235.34 434.678C235.333 434.341 235.212 434.073 234.977 433.875C234.743 433.67 234.449 433.567 234.097 433.567C233.723 433.567 233.43 433.677 233.217 433.897C233.012 434.11 232.887 434.37 232.843 434.678H235.34ZM238.91 438.11C238.522 438.11 238.21 437.993 237.975 437.758C237.748 437.523 237.634 437.171 237.634 436.702V430.333H238.954V436.614C238.954 436.841 239.083 436.955 239.339 436.955C239.464 436.955 239.603 436.933 239.757 436.889V437.945C239.464 438.055 239.182 438.11 238.91 438.11ZM241.972 438.11C241.583 438.11 241.272 437.993 241.037 437.758C240.81 437.523 240.696 437.171 240.696 436.702V430.333H242.016V436.614C242.016 436.841 242.144 436.955 242.401 436.955C242.526 436.955 242.665 436.933 242.819 436.889V437.945C242.526 438.055 242.243 438.11 241.972 438.11ZM250.843 436.416H247.84L247.257 438H245.761L248.83 430.333H249.864L252.922 438H251.426L250.843 436.416ZM250.381 435.151L249.347 432.357L248.313 435.151H250.381ZM255.031 433.622V436.383C255.031 436.596 255.09 436.753 255.207 436.856C255.332 436.959 255.504 437.01 255.724 437.01C255.908 437.01 256.128 436.97 256.384 436.889V437.945C256.054 438.055 255.724 438.11 255.394 438.11C254.903 438.11 254.5 437.978 254.184 437.714C253.869 437.443 253.711 437.032 253.711 436.482V433.622H252.831V432.577H253.711V431.312L255.031 430.333V432.577H256.384V433.622H255.031ZM258.493 438.11C258.105 438.11 257.793 437.993 257.558 437.758C257.331 437.523 257.217 437.171 257.217 436.702V430.333H258.537V436.614C258.537 436.841 258.666 436.955 258.922 436.955C259.047 436.955 259.186 436.933 259.34 436.889V437.945C259.047 438.055 258.765 438.11 258.493 438.11ZM262.403 432.467C263.121 432.467 263.686 432.658 264.097 433.039C264.515 433.413 264.724 433.926 264.724 434.579V438H263.514L263.404 437.296C263.242 437.553 263.015 437.754 262.722 437.901C262.436 438.04 262.113 438.11 261.754 438.11C261.38 438.11 261.042 438.037 260.742 437.89C260.448 437.736 260.217 437.523 260.049 437.252C259.88 436.981 259.796 436.676 259.796 436.339C259.796 436.016 259.865 435.738 260.005 435.503C260.144 435.268 260.346 435.092 260.61 434.975C260.962 434.814 261.442 434.733 262.051 434.733H263.404V434.579C263.404 434.286 263.312 434.055 263.129 433.886C262.945 433.71 262.696 433.622 262.381 433.622C262.102 433.622 261.838 433.692 261.589 433.831C261.339 433.97 261.116 434.172 260.918 434.436L259.961 433.633C260.606 432.856 261.42 432.467 262.403 432.467ZM261.963 436.988C262.359 436.988 262.696 436.867 262.975 436.625C263.261 436.376 263.404 436.075 263.404 435.723H262.227C261.801 435.723 261.504 435.785 261.336 435.91C261.189 436.013 261.116 436.163 261.116 436.361C261.116 436.552 261.189 436.706 261.336 436.823C261.49 436.933 261.699 436.988 261.963 436.988ZM267.818 438.11C267.268 438.11 266.784 437.967 266.366 437.681C265.956 437.388 265.681 437.025 265.541 436.592L266.597 436.119C266.81 436.713 267.195 437.01 267.752 437.01C268.038 437.01 268.255 436.944 268.401 436.812C268.555 436.68 268.632 436.533 268.632 436.372C268.632 436.211 268.555 436.09 268.401 436.009C268.247 435.928 267.994 435.837 267.642 435.734C267.276 435.639 266.971 435.54 266.729 435.437C266.487 435.327 266.278 435.162 266.102 434.942C265.926 434.715 265.838 434.418 265.838 434.051C265.838 433.552 266.029 433.164 266.41 432.885C266.799 432.606 267.272 432.467 267.829 432.467C268.291 432.467 268.698 432.57 269.05 432.775C269.402 432.98 269.681 433.27 269.886 433.644L268.863 434.205C268.753 434 268.614 433.835 268.445 433.71C268.277 433.578 268.057 433.512 267.785 433.512C267.58 433.512 267.411 433.556 267.279 433.644C267.155 433.732 267.092 433.842 267.092 433.974C267.092 434.121 267.169 434.234 267.323 434.315C267.485 434.396 267.73 434.48 268.06 434.568C268.442 434.678 268.757 434.788 269.006 434.898C269.256 435.008 269.472 435.177 269.655 435.404C269.839 435.631 269.93 435.928 269.93 436.295C269.93 436.698 269.828 437.036 269.622 437.307C269.424 437.578 269.164 437.78 268.841 437.912C268.519 438.044 268.178 438.11 267.818 438.11Z" fill="black" /> <g class="al-2023-active-dots green" id="active dots_2"> <circle id="Ellipse 2765_2" cx="289.583" cy="427.276" r="48.5676" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2767_2" cx="289.583" cy="427.276" r="25.309" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2771_2" cx="289.583" cy="427.276" r="13.0446" fill="white" stroke="#22704F" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot green" id="inactive dot_2" cx="289.583" cy="427.276" r="10.2374" fill="#22704F" stroke="white" stroke-width="3" /> <circle class="overlay-dot green" id="inactive dot_2" cx="289.583" cy="427.276" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="18-Zebrahub" data-milestone="zebrahub" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_19" d="M536.002 429.811L483.737 429.811C474.349 429.811 466.737 422.199 466.737 412.811V163.599C466.737 154.21 459.126 146.599 449.737 146.599L437.198 146.599" stroke="url(#paint8_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_20" d="M630.143 100.997L536.244 330.973C535.412 333.013 534.983 335.195 534.983 337.399V425.735" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M518.589 448.657L514.288 454.058H518.589V455.323H512.407V454.366L516.752 448.921H512.66V447.656H518.589V448.657ZM524.278 452.54C524.278 452.701 524.267 452.87 524.245 453.046H520.527C520.557 453.412 520.685 453.702 520.912 453.915C521.14 454.127 521.462 454.234 521.88 454.234C522.408 454.234 522.841 454.039 523.178 453.651L524.091 454.454C523.791 454.784 523.457 455.029 523.09 455.191C522.731 455.352 522.324 455.433 521.869 455.433C521.275 455.433 520.777 455.304 520.373 455.048C519.977 454.791 519.684 454.454 519.493 454.036C519.303 453.61 519.207 453.145 519.207 452.639C519.207 452.14 519.299 451.674 519.482 451.242C519.673 450.809 519.959 450.461 520.34 450.197C520.729 449.925 521.209 449.79 521.781 449.79C522.324 449.79 522.782 449.911 523.156 450.153C523.53 450.395 523.809 450.725 523.992 451.143C524.183 451.561 524.278 452.026 524.278 452.54ZM523.013 452.001C523.006 451.663 522.885 451.396 522.65 451.198C522.416 450.992 522.122 450.89 521.77 450.89C521.396 450.89 521.103 451 520.89 451.22C520.685 451.432 520.56 451.693 520.516 452.001H523.013ZM528.256 449.79C528.703 449.79 529.099 449.903 529.444 450.131C529.788 450.351 530.056 450.673 530.247 451.099C530.445 451.524 530.544 452.026 530.544 452.606C530.544 453.442 530.342 454.124 529.939 454.652C529.535 455.172 528.974 455.433 528.256 455.433C527.948 455.433 527.654 455.381 527.376 455.279C527.097 455.169 526.87 455.004 526.694 454.784V455.323H525.374V447.656H526.694V450.45C526.862 450.244 527.086 450.083 527.365 449.966C527.651 449.848 527.948 449.79 528.256 449.79ZM527.937 454.212C528.369 454.212 528.692 454.076 528.905 453.805C529.117 453.526 529.224 453.13 529.224 452.617C529.224 452.096 529.114 451.696 528.894 451.418C528.681 451.132 528.358 450.989 527.926 450.989C527.478 450.989 527.141 451.139 526.914 451.44C526.686 451.74 526.573 452.133 526.573 452.617C526.573 453.093 526.686 453.478 526.914 453.772C527.141 454.065 527.482 454.212 527.937 454.212ZM534.451 449.79C534.811 449.79 535.155 449.892 535.485 450.098L534.847 451.264C534.657 451.139 534.437 451.077 534.187 451.077C533.388 451.077 532.988 451.583 532.988 452.595V455.323H531.668V449.9H532.999V450.824C533.109 450.501 533.296 450.248 533.56 450.065C533.832 449.881 534.129 449.79 534.451 449.79ZM538.292 449.79C539.01 449.79 539.575 449.98 539.986 450.362C540.404 450.736 540.613 451.249 540.613 451.902V455.323H539.403L539.293 454.619C539.131 454.875 538.904 455.077 538.611 455.224C538.325 455.363 538.002 455.433 537.643 455.433C537.269 455.433 536.931 455.359 536.631 455.213C536.337 455.059 536.106 454.846 535.938 454.575C535.769 454.303 535.685 453.999 535.685 453.662C535.685 453.339 535.754 453.06 535.894 452.826C536.033 452.591 536.235 452.415 536.499 452.298C536.851 452.136 537.331 452.056 537.94 452.056H539.293V451.902C539.293 451.608 539.201 451.377 539.018 451.209C538.834 451.033 538.585 450.945 538.27 450.945C537.991 450.945 537.727 451.014 537.478 451.154C537.228 451.293 537.005 451.495 536.807 451.759L535.85 450.956C536.495 450.178 537.309 449.79 538.292 449.79ZM537.852 454.311C538.248 454.311 538.585 454.19 538.864 453.948C539.15 453.698 539.293 453.398 539.293 453.046H538.116C537.69 453.046 537.393 453.108 537.225 453.233C537.078 453.335 537.005 453.486 537.005 453.684C537.005 453.874 537.078 454.028 537.225 454.146C537.379 454.256 537.588 454.311 537.852 454.311ZM544.972 449.79C545.581 449.79 546.05 449.966 546.38 450.318C546.718 450.67 546.886 451.172 546.886 451.825V455.323H545.566V452.155C545.566 451.744 545.486 451.44 545.324 451.242C545.163 451.044 544.91 450.945 544.565 450.945C544.133 450.945 543.817 451.121 543.619 451.473C543.429 451.817 543.333 452.378 543.333 453.156V455.323H542.013V447.656H543.333V450.516C543.707 450.032 544.254 449.79 544.972 449.79ZM553.006 449.9V455.323H551.686V454.696C551.503 454.945 551.268 455.132 550.982 455.257C550.703 455.374 550.399 455.433 550.069 455.433C549.424 455.433 548.94 455.231 548.617 454.828C548.294 454.424 548.133 453.911 548.133 453.288V449.9H549.453V452.958C549.453 453.302 549.512 453.61 549.629 453.882C549.746 454.146 550.021 454.278 550.454 454.278C550.835 454.278 551.114 454.16 551.29 453.926C551.473 453.691 551.583 453.42 551.62 453.112C551.664 452.804 551.686 452.419 551.686 451.957V449.9H553.006ZM557.442 449.79C557.889 449.79 558.285 449.903 558.63 450.131C558.975 450.351 559.242 450.673 559.433 451.099C559.631 451.524 559.73 452.026 559.73 452.606C559.73 453.442 559.528 454.124 559.125 454.652C558.722 455.172 558.161 455.433 557.442 455.433C557.134 455.433 556.841 455.381 556.562 455.279C556.283 455.169 556.056 455.004 555.88 454.784V455.323H554.56V447.656H555.88V450.45C556.049 450.244 556.272 450.083 556.551 449.966C556.837 449.848 557.134 449.79 557.442 449.79ZM557.123 454.212C557.556 454.212 557.878 454.076 558.091 453.805C558.304 453.526 558.41 453.13 558.41 452.617C558.41 452.096 558.3 451.696 558.08 451.418C557.867 451.132 557.545 450.989 557.112 450.989C556.665 450.989 556.327 451.139 556.1 451.44C555.873 451.74 555.759 452.133 555.759 452.617C555.759 453.093 555.873 453.478 556.1 453.772C556.327 454.065 556.668 454.212 557.123 454.212Z" fill="black" /> <g class="al-2023-active-dots navy" id="active dots_3"> <circle id="Ellipse 2765_3" cx="535.474" cy="427.275" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_3" cx="535.474" cy="427.275" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_3" cx="535.474" cy="427.276" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive dot_3" cx="535.474" cy="427.275" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_3" cx="535.474" cy="427.275" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="17-CryoET-Data-Portal" data-milestone="cryoet-data-portal" class="al-2023-svg-milestone"> <line class="al-2023-connector-line" id="connector-line_21" x1="680.778" y1="379.824" x2="633.455" y2="427.55" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M618.032 455.493C615.854 455.493 614.363 453.893 614.363 451.484C614.363 449.086 615.848 447.485 618.032 447.485C619.66 447.485 620.897 448.349 621.414 449.773L620.078 450.257C619.742 449.366 619.022 448.844 618.032 448.844C616.662 448.844 615.788 449.85 615.788 451.484C615.788 453.128 616.662 454.135 618.032 454.135C619.022 454.135 619.742 453.612 620.078 452.721L621.414 453.2C620.897 454.624 619.66 455.493 618.032 455.493ZM622.415 455.323V449.9H623.79V450.653C624.109 450.12 624.697 449.79 625.253 449.79C625.599 449.79 625.913 449.878 626.276 450.098L625.616 451.33C625.451 451.236 625.176 451.154 624.928 451.154C624.483 451.154 624.07 451.379 623.889 451.907C623.817 452.127 623.784 452.38 623.784 452.991V455.323H622.415ZM627.538 457.561L628.638 454.905L626.592 449.9H628.094L629.364 453.541L630.662 449.9H632.136L629.023 457.561H627.538ZM635.267 455.433C633.694 455.433 632.539 454.245 632.539 452.606C632.539 450.972 633.677 449.79 635.267 449.79C636.845 449.79 637.989 450.972 637.989 452.606C637.989 454.234 636.834 455.433 635.267 455.433ZM633.903 452.606C633.903 453.618 634.414 454.228 635.267 454.228C636.119 454.228 636.62 453.618 636.62 452.606C636.62 451.588 636.119 450.989 635.267 450.989C634.409 450.989 633.903 451.594 633.903 452.606ZM639.153 455.323V447.656H644.262V448.926H640.577V450.752H644.015V452.023H640.577V454.052H644.262V455.323H639.153ZM647.272 455.323V448.926H644.896V447.656H651.078V448.926H648.713V455.323H647.272ZM604.998 467.323V459.656H607.231C609.772 459.656 611.235 461.069 611.235 463.55C611.235 465.986 609.816 467.323 607.22 467.323H604.998ZM606.422 466.014H607.082C608.804 466.014 609.799 465.442 609.799 463.495C609.799 461.597 608.82 460.965 607.209 460.965H606.422V466.014ZM615.82 467.323L615.732 466.679C615.341 467.246 614.764 467.433 614.181 467.433C612.987 467.433 612.113 466.723 612.113 465.645C612.113 465.029 612.388 464.573 612.822 464.325C613.18 464.116 613.642 464.028 614.148 464.028H615.71V463.896C615.71 463.33 615.325 462.978 614.599 462.978C614.12 462.978 613.669 463.137 613.185 463.643L612.201 462.813C612.844 462.103 613.763 461.79 614.698 461.79C616.194 461.79 617.074 462.587 617.074 463.896V467.323H615.82ZM613.482 465.651C613.482 466.063 613.829 466.327 614.379 466.327C615.105 466.327 615.71 465.81 615.71 465.095V465.046H614.346C614.104 465.046 613.873 465.079 613.708 465.194C613.559 465.299 613.482 465.453 613.482 465.651ZM620.538 467.433C619.663 467.433 618.899 466.982 618.899 465.733V462.961H617.909V461.9H618.899V460.64L620.285 459.892V461.9H621.462V462.961H620.285V465.354C620.285 465.981 620.422 466.311 620.912 466.311C621.055 466.311 621.247 466.278 621.462 466.217V467.268C621.165 467.378 620.851 467.433 620.538 467.433ZM626.004 467.323L625.916 466.679C625.525 467.246 624.948 467.433 624.365 467.433C623.171 467.433 622.297 466.723 622.297 465.645C622.297 465.029 622.572 464.573 623.006 464.325C623.364 464.116 623.826 464.028 624.332 464.028H625.894V463.896C625.894 463.33 625.509 462.978 624.783 462.978C624.304 462.978 623.853 463.137 623.369 463.643L622.385 462.813C623.028 462.103 623.947 461.79 624.882 461.79C626.378 461.79 627.258 462.587 627.258 463.896V467.323H626.004ZM623.666 465.651C623.666 466.063 624.013 466.327 624.563 466.327C625.289 466.327 625.894 465.81 625.894 465.095V465.046H624.53C624.288 465.046 624.057 465.079 623.892 465.194C623.743 465.299 623.666 465.453 623.666 465.651ZM631.456 467.323V459.656H633.986C635.713 459.656 636.604 460.398 636.604 461.878C636.604 463.363 635.691 464.155 633.986 464.155H632.869V467.323H631.456ZM632.869 462.89H633.843C634.69 462.89 635.185 462.626 635.185 461.894C635.185 461.185 634.734 460.926 633.843 460.926H632.869V462.89ZM639.752 467.433C638.179 467.433 637.024 466.245 637.024 464.606C637.024 462.972 638.162 461.79 639.752 461.79C641.33 461.79 642.474 462.972 642.474 464.606C642.474 466.234 641.319 467.433 639.752 467.433ZM638.388 464.606C638.388 465.618 638.899 466.228 639.752 466.228C640.604 466.228 641.105 465.618 641.105 464.606C641.105 463.588 640.604 462.989 639.752 462.989C638.894 462.989 638.388 463.594 638.388 464.606ZM643.572 467.323V461.9H644.947V462.653C645.266 462.12 645.854 461.79 646.41 461.79C646.756 461.79 647.07 461.878 647.433 462.098L646.773 463.33C646.608 463.236 646.333 463.154 646.085 463.154C645.64 463.154 645.227 463.379 645.046 463.907C644.974 464.127 644.941 464.38 644.941 464.991V467.323H643.572ZM650.444 467.433C649.57 467.433 648.805 466.982 648.805 465.733V462.961H647.815V461.9H648.805V460.64L650.191 459.892V461.9H651.368V462.961H650.191V465.354C650.191 465.981 650.329 466.311 650.818 466.311C650.961 466.311 651.154 466.278 651.368 466.217V467.268C651.071 467.378 650.758 467.433 650.444 467.433ZM655.91 467.323L655.822 466.679C655.431 467.246 654.854 467.433 654.271 467.433C653.077 467.433 652.203 466.723 652.203 465.645C652.203 465.029 652.478 464.573 652.912 464.325C653.27 464.116 653.732 464.028 654.238 464.028H655.8V463.896C655.8 463.33 655.415 462.978 654.689 462.978C654.21 462.978 653.759 463.137 653.275 463.643L652.291 462.813C652.934 462.103 653.853 461.79 654.788 461.79C656.284 461.79 657.164 462.587 657.164 463.896V467.323H655.91ZM653.572 465.651C653.572 466.063 653.919 466.327 654.469 466.327C655.195 466.327 655.8 465.81 655.8 465.095V465.046H654.436C654.194 465.046 653.963 465.079 653.798 465.194C653.649 465.299 653.572 465.453 653.572 465.651ZM659.704 467.433C658.961 467.433 658.411 467.004 658.411 466.019V459.656H659.77V465.75C659.77 466.052 659.935 466.168 660.166 466.168C660.281 466.168 660.413 466.146 660.556 466.102V467.262C660.254 467.383 659.935 467.433 659.704 467.433Z" fill="black" /> <g class="al-2023-active-dots navy" id="active dots_4"> <circle id="Ellipse 2765_4" cx="630.374" cy="427.276" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_4" cx="630.374" cy="427.276" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_4" cx="630.374" cy="427.276" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive dot_4" cx="630.374" cy="427.276" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_4" cx="630.374" cy="427.276" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="16-Biohub-New-York-Chicago" data-milestone="biohub-new-york-chicago" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_22" d="M728.505 334.898L776.211 427.644" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_23" d="M725.417 336.977L724.895 428.9" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M706.852 447.656H709.525C710.287 447.656 710.881 447.828 711.307 448.173C711.739 448.51 711.956 448.983 711.956 449.592C711.956 449.951 711.882 450.27 711.736 450.549C711.589 450.82 711.38 451.033 711.109 451.187C711.945 451.488 712.363 452.118 712.363 453.079C712.363 453.783 712.143 454.333 711.703 454.729C711.263 455.125 710.65 455.323 709.866 455.323H706.852V447.656ZM709.525 450.703C709.869 450.703 710.13 450.63 710.306 450.483C710.489 450.336 710.581 450.12 710.581 449.834C710.581 449.541 710.489 449.317 710.306 449.163C710.122 449.002 709.862 448.921 709.525 448.921H708.227V450.703H709.525ZM709.756 454.058C710.137 454.058 710.438 453.963 710.658 453.772C710.878 453.574 710.988 453.306 710.988 452.969C710.988 452.646 710.881 452.401 710.669 452.232C710.463 452.056 710.159 451.968 709.756 451.968H708.227V454.058H709.756ZM713.572 449.9H714.892V455.323H713.572V449.9ZM713.539 447.656H714.925V448.877H713.539V447.656ZM718.662 455.433C718.119 455.433 717.639 455.308 717.221 455.059C716.81 454.802 716.495 454.458 716.275 454.025C716.055 453.592 715.945 453.119 715.945 452.606C715.945 452.093 716.055 451.623 716.275 451.198C716.495 450.765 716.81 450.424 717.221 450.175C717.639 449.918 718.119 449.79 718.662 449.79C719.205 449.79 719.681 449.918 720.092 450.175C720.503 450.424 720.818 450.765 721.038 451.198C721.265 451.623 721.379 452.093 721.379 452.606C721.379 453.119 721.265 453.592 721.038 454.025C720.818 454.458 720.503 454.802 720.092 455.059C719.681 455.308 719.205 455.433 718.662 455.433ZM718.662 454.278C719.131 454.278 719.48 454.12 719.707 453.805C719.942 453.49 720.059 453.09 720.059 452.606C720.059 452.122 719.942 451.726 719.707 451.418C719.48 451.103 719.131 450.945 718.662 450.945C718.193 450.945 717.841 451.103 717.606 451.418C717.379 451.726 717.265 452.122 717.265 452.606C717.265 453.09 717.379 453.49 717.606 453.805C717.841 454.12 718.193 454.278 718.662 454.278ZM725.404 449.79C726.013 449.79 726.482 449.966 726.812 450.318C727.149 450.67 727.318 451.172 727.318 451.825V455.323H725.998V452.155C725.998 451.744 725.917 451.44 725.756 451.242C725.595 451.044 725.342 450.945 724.997 450.945C724.564 450.945 724.249 451.121 724.051 451.473C723.86 451.818 723.765 452.379 723.765 453.156V455.323H722.445V447.656H723.765V450.516C724.139 450.032 724.685 449.79 725.404 449.79ZM733.438 449.9V455.323H732.118V454.696C731.934 454.945 731.7 455.132 731.414 455.257C731.135 455.374 730.831 455.433 730.501 455.433C729.855 455.433 729.371 455.231 729.049 454.828C728.726 454.425 728.565 453.911 728.565 453.288V449.9H729.885V452.958C729.885 453.303 729.943 453.611 730.061 453.882C730.178 454.146 730.453 454.278 730.886 454.278C731.267 454.278 731.546 454.161 731.722 453.926C731.905 453.691 732.015 453.42 732.052 453.112C732.096 452.804 732.118 452.419 732.118 451.957V449.9H733.438ZM737.874 449.79C738.321 449.79 738.717 449.904 739.062 450.131C739.406 450.351 739.674 450.674 739.865 451.099C740.063 451.524 740.162 452.027 740.162 452.606C740.162 453.442 739.96 454.124 739.557 454.652C739.153 455.173 738.592 455.433 737.874 455.433C737.566 455.433 737.272 455.382 736.994 455.279C736.715 455.169 736.488 455.004 736.312 454.784V455.323H734.992V447.656H736.312V450.45C736.48 450.245 736.704 450.083 736.983 449.966C737.269 449.849 737.566 449.79 737.874 449.79ZM737.555 454.212C737.987 454.212 738.31 454.076 738.523 453.805C738.735 453.526 738.842 453.13 738.842 452.617C738.842 452.096 738.732 451.697 738.512 451.418C738.299 451.132 737.976 450.989 737.544 450.989C737.096 450.989 736.759 451.139 736.532 451.44C736.304 451.741 736.191 452.133 736.191 452.617C736.191 453.094 736.304 453.479 736.532 453.772C736.759 454.065 737.1 454.212 737.555 454.212ZM707.479 467.488C706.731 467.488 706.075 467.327 705.51 467.004C704.953 466.674 704.52 466.208 704.212 465.607C703.911 464.998 703.761 464.291 703.761 463.484C703.761 462.677 703.911 461.973 704.212 461.372C704.52 460.763 704.953 460.298 705.51 459.975C706.075 459.645 706.731 459.48 707.479 459.48C708.293 459.48 708.993 459.674 709.58 460.063C710.167 460.444 710.599 460.998 710.878 461.724L709.613 462.219C709.444 461.742 709.177 461.387 708.81 461.152C708.451 460.91 708.007 460.789 707.479 460.789C706.738 460.789 706.163 461.024 705.752 461.493C705.341 461.955 705.136 462.615 705.136 463.473C705.136 464.331 705.341 464.998 705.752 465.475C706.163 465.944 706.738 466.179 707.479 466.179C708.007 466.179 708.454 466.058 708.821 465.816C709.188 465.567 709.452 465.2 709.613 464.716L710.9 465.2C710.629 465.941 710.196 466.509 709.602 466.905C709.008 467.294 708.3 467.488 707.479 467.488ZM714.775 461.79C715.383 461.79 715.853 461.966 716.183 462.318C716.52 462.67 716.689 463.172 716.689 463.825V467.323H715.369V464.155C715.369 463.744 715.288 463.44 715.127 463.242C714.965 463.044 714.712 462.945 714.368 462.945C713.935 462.945 713.62 463.121 713.422 463.473C713.231 463.818 713.136 464.379 713.136 465.156V467.323H711.816V459.656H713.136V462.516C713.51 462.032 714.056 461.79 714.775 461.79ZM718.11 461.9H719.43V467.323H718.11V461.9ZM718.077 459.656H719.463V460.877H718.077V459.656ZM723.124 467.433C722.559 467.433 722.079 467.305 721.683 467.048C721.287 466.784 720.99 466.439 720.792 466.014C720.594 465.581 720.495 465.119 720.495 464.628C720.495 464.129 720.594 463.667 720.792 463.242C720.99 462.809 721.283 462.461 721.672 462.197C722.068 461.926 722.548 461.79 723.113 461.79C723.663 461.79 724.139 461.926 724.543 462.197C724.946 462.461 725.25 462.857 725.456 463.385L724.202 463.88C724.128 463.594 723.993 463.367 723.795 463.198C723.604 463.029 723.377 462.945 723.113 462.945C722.687 462.945 722.368 463.106 722.156 463.429C721.95 463.752 721.848 464.151 721.848 464.628C721.848 465.105 721.95 465.501 722.156 465.816C722.361 466.124 722.68 466.278 723.113 466.278C723.377 466.278 723.604 466.197 723.795 466.036C723.993 465.867 724.128 465.644 724.202 465.365L725.401 465.827C725.217 466.333 724.924 466.729 724.521 467.015C724.125 467.294 723.659 467.433 723.124 467.433ZM728.483 461.79C729.201 461.79 729.766 461.981 730.177 462.362C730.595 462.736 730.804 463.249 730.804 463.902V467.323H729.594L729.484 466.619C729.322 466.876 729.095 467.077 728.802 467.224C728.516 467.363 728.193 467.433 727.834 467.433C727.46 467.433 727.122 467.36 726.822 467.213C726.528 467.059 726.297 466.846 726.129 466.575C725.96 466.304 725.876 465.999 725.876 465.662C725.876 465.339 725.945 465.061 726.085 464.826C726.224 464.591 726.426 464.415 726.69 464.298C727.042 464.137 727.522 464.056 728.131 464.056H729.484V463.902C729.484 463.609 729.392 463.378 729.209 463.209C729.025 463.033 728.776 462.945 728.461 462.945C728.182 462.945 727.918 463.015 727.669 463.154C727.419 463.293 727.196 463.495 726.998 463.759L726.041 462.956C726.686 462.179 727.5 461.79 728.483 461.79ZM728.043 466.311C728.439 466.311 728.776 466.19 729.055 465.948C729.341 465.699 729.484 465.398 729.484 465.046H728.307C727.881 465.046 727.584 465.108 727.416 465.233C727.269 465.336 727.196 465.486 727.196 465.684C727.196 465.875 727.269 466.029 727.416 466.146C727.57 466.256 727.779 466.311 728.043 466.311ZM734.251 466.498C734.808 466.571 735.244 466.645 735.56 466.718C735.875 466.791 736.154 466.934 736.396 467.147C736.645 467.36 736.77 467.664 736.77 468.06C736.77 468.603 736.546 469.006 736.099 469.27C735.651 469.541 735.043 469.677 734.273 469.677C733.459 469.677 732.832 469.53 732.392 469.237C731.952 468.944 731.732 468.518 731.732 467.961C731.732 467.873 731.739 467.792 731.754 467.719L732.535 467.224C732.102 466.989 731.886 466.619 731.886 466.113C731.886 465.68 732.054 465.317 732.392 465.024C732.098 464.657 731.952 464.243 731.952 463.781C731.952 463.4 732.051 463.059 732.249 462.758C732.454 462.45 732.725 462.212 733.063 462.043C733.4 461.874 733.77 461.79 734.174 461.79C734.65 461.79 735.076 461.904 735.45 462.131L736.275 461.427L736.968 462.263L736.187 462.901C736.341 463.194 736.418 463.51 736.418 463.847C736.418 464.236 736.319 464.58 736.121 464.881C735.923 465.182 735.655 465.416 735.318 465.585C734.98 465.746 734.614 465.827 734.218 465.827C733.858 465.827 733.51 465.757 733.173 465.618C733.07 465.684 733.019 465.779 733.019 465.904C733.019 466.087 733.121 466.219 733.327 466.3C733.532 466.381 733.84 466.447 734.251 466.498ZM734.196 462.89C733.917 462.89 733.693 462.974 733.525 463.143C733.356 463.312 733.272 463.535 733.272 463.814C733.272 464.085 733.352 464.309 733.514 464.485C733.675 464.661 733.902 464.749 734.196 464.749C734.489 464.749 734.713 464.665 734.867 464.496C735.021 464.32 735.098 464.093 735.098 463.814C735.098 463.535 735.017 463.312 734.856 463.143C734.694 462.974 734.474 462.89 734.196 462.89ZM734.328 468.687C734.643 468.687 734.907 468.647 735.12 468.566C735.34 468.485 735.45 468.357 735.45 468.181C735.45 468.012 735.351 467.895 735.153 467.829C734.955 467.763 734.643 467.701 734.218 467.642L733.976 467.609L733.525 467.543L733.052 467.994C733.044 468.016 733.041 468.045 733.041 468.082C733.041 468.295 733.165 468.449 733.415 468.544C733.664 468.639 733.968 468.687 734.328 468.687ZM740.055 467.433C739.512 467.433 739.032 467.308 738.614 467.059C738.203 466.802 737.888 466.458 737.668 466.025C737.448 465.592 737.338 465.119 737.338 464.606C737.338 464.093 737.448 463.623 737.668 463.198C737.888 462.765 738.203 462.424 738.614 462.175C739.032 461.918 739.512 461.79 740.055 461.79C740.598 461.79 741.074 461.918 741.485 462.175C741.896 462.424 742.211 462.765 742.431 463.198C742.658 463.623 742.772 464.093 742.772 464.606C742.772 465.119 742.658 465.592 742.431 466.025C742.211 466.458 741.896 466.802 741.485 467.059C741.074 467.308 740.598 467.433 740.055 467.433ZM740.055 466.278C740.524 466.278 740.873 466.12 741.1 465.805C741.335 465.49 741.452 465.09 741.452 464.606C741.452 464.122 741.335 463.726 741.1 463.418C740.873 463.103 740.524 462.945 740.055 462.945C739.586 462.945 739.234 463.103 738.999 463.418C738.772 463.726 738.658 464.122 738.658 464.606C738.658 465.09 738.772 465.49 738.999 465.805C739.234 466.12 739.586 466.278 740.055 466.278Z" fill="black" /> <path class="al-2023-svg-text" d="M761.473 447.656H764.146C764.909 447.656 765.503 447.828 765.928 448.173C766.361 448.51 766.577 448.983 766.577 449.592C766.577 449.951 766.504 450.27 766.357 450.549C766.211 450.82 766.002 451.033 765.73 451.187C766.566 451.488 766.984 452.118 766.984 453.079C766.984 453.783 766.764 454.333 766.324 454.729C765.884 455.125 765.272 455.323 764.487 455.323H761.473V447.656ZM764.146 450.703C764.491 450.703 764.751 450.63 764.927 450.483C765.111 450.336 765.202 450.12 765.202 449.834C765.202 449.541 765.111 449.317 764.927 449.163C764.744 449.002 764.484 448.921 764.146 448.921H762.848V450.703H764.146ZM764.377 454.058C764.759 454.058 765.059 453.963 765.279 453.772C765.499 453.574 765.609 453.306 765.609 452.969C765.609 452.646 765.503 452.401 765.29 452.232C765.085 452.056 764.781 451.968 764.377 451.968H762.848V454.058H764.377ZM768.193 449.9H769.513V455.323H768.193V449.9ZM768.16 447.656H769.546V448.877H768.16V447.656ZM773.284 455.433C772.741 455.433 772.261 455.308 771.843 455.059C771.432 454.802 771.117 454.458 770.897 454.025C770.677 453.592 770.567 453.119 770.567 452.606C770.567 452.093 770.677 451.623 770.897 451.198C771.117 450.765 771.432 450.424 771.843 450.175C772.261 449.918 772.741 449.79 773.284 449.79C773.826 449.79 774.303 449.918 774.714 450.175C775.124 450.424 775.44 450.765 775.66 451.198C775.887 451.623 776.001 452.093 776.001 452.606C776.001 453.119 775.887 453.592 775.66 454.025C775.44 454.458 775.124 454.802 774.714 455.059C774.303 455.308 773.826 455.433 773.284 455.433ZM773.284 454.278C773.753 454.278 774.101 454.12 774.329 453.805C774.563 453.49 774.681 453.09 774.681 452.606C774.681 452.122 774.563 451.726 774.329 451.418C774.101 451.103 773.753 450.945 773.284 450.945C772.814 450.945 772.462 451.103 772.228 451.418C772 451.726 771.887 452.122 771.887 452.606C771.887 453.09 772 453.49 772.228 453.805C772.462 454.12 772.814 454.278 773.284 454.278ZM780.026 449.79C780.634 449.79 781.104 449.966 781.434 450.318C781.771 450.67 781.94 451.172 781.94 451.825V455.323H780.62V452.155C780.62 451.744 780.539 451.44 780.378 451.242C780.216 451.044 779.963 450.945 779.619 450.945C779.186 450.945 778.871 451.121 778.673 451.473C778.482 451.818 778.387 452.379 778.387 453.156V455.323H777.067V447.656H778.387V450.516C778.761 450.032 779.307 449.79 780.026 449.79ZM788.059 449.9V455.323H786.739V454.696C786.556 454.945 786.321 455.132 786.035 455.257C785.757 455.374 785.452 455.433 785.122 455.433C784.477 455.433 783.993 455.231 783.67 454.828C783.348 454.425 783.186 453.911 783.186 453.288V449.9H784.506V452.958C784.506 453.303 784.565 453.611 784.682 453.882C784.8 454.146 785.075 454.278 785.507 454.278C785.889 454.278 786.167 454.161 786.343 453.926C786.527 453.691 786.637 453.42 786.673 453.112C786.717 452.804 786.739 452.419 786.739 451.957V449.9H788.059ZM792.495 449.79C792.943 449.79 793.339 449.904 793.683 450.131C794.028 450.351 794.296 450.674 794.486 451.099C794.684 451.524 794.783 452.027 794.783 452.606C794.783 453.442 794.582 454.124 794.178 454.652C793.775 455.173 793.214 455.433 792.495 455.433C792.187 455.433 791.894 455.382 791.615 455.279C791.337 455.169 791.109 455.004 790.933 454.784V455.323H789.613V447.656H790.933V450.45C791.102 450.245 791.326 450.083 791.604 449.966C791.89 449.849 792.187 449.79 792.495 449.79ZM792.176 454.212C792.609 454.212 792.932 454.076 793.144 453.805C793.357 453.526 793.463 453.13 793.463 452.617C793.463 452.096 793.353 451.697 793.133 451.418C792.921 451.132 792.598 450.989 792.165 450.989C791.718 450.989 791.381 451.139 791.153 451.44C790.926 451.741 790.812 452.133 790.812 452.617C790.812 453.094 790.926 453.479 791.153 453.772C791.381 454.065 791.722 454.212 792.176 454.212ZM761.416 459.656V467.323H759.986L756.774 462.021V467.323H755.399V459.656H756.818L760.041 464.936V459.656H761.416ZM767.738 464.54C767.738 464.701 767.727 464.87 767.705 465.046H763.987C764.016 465.413 764.144 465.702 764.372 465.915C764.599 466.128 764.922 466.234 765.34 466.234C765.868 466.234 766.3 466.04 766.638 465.651L767.551 466.454C767.25 466.784 766.916 467.03 766.55 467.191C766.19 467.352 765.783 467.433 765.329 467.433C764.735 467.433 764.236 467.305 763.833 467.048C763.437 466.791 763.143 466.454 762.953 466.036C762.762 465.611 762.667 465.145 762.667 464.639C762.667 464.14 762.758 463.675 762.942 463.242C763.132 462.809 763.418 462.461 763.8 462.197C764.188 461.926 764.669 461.79 765.241 461.79C765.783 461.79 766.242 461.911 766.616 462.153C766.99 462.395 767.268 462.725 767.452 463.143C767.642 463.561 767.738 464.027 767.738 464.54ZM766.473 464.001C766.465 463.664 766.344 463.396 766.11 463.198C765.875 462.993 765.582 462.89 765.23 462.89C764.856 462.89 764.562 463 764.35 463.22C764.144 463.433 764.02 463.693 763.976 464.001H766.473ZM768.096 461.9H769.504L770.428 465.299L771.451 461.9H772.584L773.607 465.288L774.542 461.9H775.95L774.278 467.323H773.09L772.023 463.77L770.956 467.323H769.768L768.096 461.9ZM781.547 464.331L778.632 459.656H780.249L782.207 463.011L784.187 459.656H785.815L782.922 464.331V467.323H781.547V464.331ZM787.694 467.433C787.152 467.433 786.671 467.308 786.253 467.059C785.843 466.802 785.527 466.458 785.307 466.025C785.087 465.592 784.977 465.119 784.977 464.606C784.977 464.093 785.087 463.623 785.307 463.198C785.527 462.765 785.843 462.424 786.253 462.175C786.671 461.918 787.152 461.79 787.694 461.79C788.237 461.79 788.714 461.918 789.124 462.175C789.535 462.424 789.85 462.765 790.07 463.198C790.298 463.623 790.411 464.093 790.411 464.606C790.411 465.119 790.298 465.592 790.07 466.025C789.85 466.458 789.535 466.802 789.124 467.059C788.714 467.308 788.237 467.433 787.694 467.433ZM787.694 466.278C788.164 466.278 788.512 466.12 788.739 465.805C788.974 465.49 789.091 465.09 789.091 464.606C789.091 464.122 788.974 463.726 788.739 463.418C788.512 463.103 788.164 462.945 787.694 462.945C787.225 462.945 786.873 463.103 786.638 463.418C786.411 463.726 786.297 464.122 786.297 464.606C786.297 465.09 786.411 465.49 786.638 465.805C786.873 466.12 787.225 466.278 787.694 466.278ZM794.249 461.79C794.609 461.79 794.953 461.893 795.283 462.098L794.645 463.264C794.455 463.139 794.235 463.077 793.985 463.077C793.186 463.077 792.786 463.583 792.786 464.595V467.323H791.466V461.9H792.797V462.824C792.907 462.501 793.094 462.248 793.358 462.065C793.63 461.882 793.927 461.79 794.249 461.79ZM795.967 459.656H797.287V464.1L799.278 461.9H801.049L799.025 464.001L801.28 467.323H799.707L798.123 464.815L797.287 465.739V467.323H795.967V459.656Z" fill="black" /> <g class="al-2023-active-dots navy" id="active dots_5"> <circle id="Ellipse 2765_5" cx="775.781" cy="427.276" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_5" cx="775.781" cy="427.276" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_5" cx="775.781" cy="427.276" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <g class="al-2023-active-dots navy" id="active dots_6"> <circle id="Ellipse 2765_6" cx="725.275" cy="427.276" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_6" cx="725.276" cy="427.276" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_6" cx="725.275" cy="427.276" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive dot_5" cx="725.275" cy="427.276" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_5" cx="725.275" cy="427.276" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> <circle class="al-2023-inactive-dot navy" id="inactive dot_6" cx="775.781" cy="427.276" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_6" cx="775.781" cy="427.276" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="15-Tabula-Sapiens" data-milestone="tabula-sapiens" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="Vector 316_2" d="M567.882 381.335L424.986 381.336C417.852 381.336 412.069 375.553 412.069 368.42L412.069 294.276C412.069 289.866 409.819 285.761 406.102 283.388L340.782 241.703" stroke="url(#paint9_linear_42_3042)" stroke-width="1.51955" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_24" d="M568.518 375.386L493.459 375.386C484.07 375.386 476.459 367.775 476.459 358.386V163.599C476.459 154.21 468.848 146.599 459.459 146.599L457.57 146.599" stroke="url(#paint10_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_25" d="M147.335 209V211C147.335 216.523 151.813 221 157.335 221H551C567.016 221 580 233.984 580 250L580 373.023" stroke="url(#paint11_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" stroke-linejoin="round" /> <path class="al-2023-connector-line" id="connector-line_26" d="M630.375 101.969L581.749 379.763" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M499.98 364.95V358.554H497.604V357.283H503.786V358.554H501.421V364.95H499.98ZM507.098 364.95L507.01 364.307C506.619 364.873 506.042 365.06 505.459 365.06C504.265 365.06 503.391 364.351 503.391 363.273C503.391 362.657 503.666 362.2 504.1 361.953C504.458 361.744 504.92 361.656 505.426 361.656H506.988V361.524C506.988 360.957 506.603 360.605 505.877 360.605C505.398 360.605 504.947 360.765 504.463 361.271L503.479 360.44C504.122 359.731 505.041 359.417 505.976 359.417C507.472 359.417 508.352 360.215 508.352 361.524V364.95H507.098ZM504.76 363.278C504.76 363.691 505.107 363.955 505.657 363.955C506.383 363.955 506.988 363.438 506.988 362.723V362.673H505.624C505.382 362.673 505.151 362.706 504.986 362.822C504.837 362.926 504.76 363.08 504.76 363.278ZM512.542 365.06C511.948 365.06 511.37 364.857 510.991 364.235V364.95H509.632V357.283H510.991V360.248C511.337 359.681 511.915 359.417 512.542 359.417C513.823 359.417 514.857 360.462 514.857 362.233C514.857 363.85 513.977 365.06 512.542 365.06ZM510.87 362.233C510.87 363.185 511.376 363.806 512.173 363.806C512.971 363.806 513.488 363.19 513.488 362.233C513.488 361.282 512.971 360.671 512.173 360.671C511.376 360.671 510.87 361.287 510.87 362.233ZM517.889 365.06C516.553 365.06 515.909 364.224 515.909 362.915V359.527H517.279V362.574C517.279 363.328 517.493 363.867 518.296 363.867C519.259 363.867 519.462 363.009 519.462 361.683V359.527H520.826V364.95H519.462V364.268C519.099 364.829 518.533 365.06 517.889 365.06ZM523.449 365.06C522.707 365.06 522.157 364.631 522.157 363.647V357.283H523.515V363.377C523.515 363.68 523.68 363.795 523.911 363.795C524.027 363.795 524.159 363.773 524.302 363.729V364.89C523.999 365.011 523.68 365.06 523.449 365.06ZM528.765 364.95L528.677 364.307C528.286 364.873 527.709 365.06 527.126 365.06C525.932 365.06 525.058 364.351 525.058 363.273C525.058 362.657 525.333 362.2 525.767 361.953C526.125 361.744 526.587 361.656 527.093 361.656H528.655V361.524C528.655 360.957 528.27 360.605 527.544 360.605C527.065 360.605 526.614 360.765 526.13 361.271L525.146 360.44C525.789 359.731 526.708 359.417 527.643 359.417C529.139 359.417 530.019 360.215 530.019 361.524V364.95H528.765ZM526.427 363.278C526.427 363.691 526.774 363.955 527.324 363.955C528.05 363.955 528.655 363.438 528.655 362.723V362.673H527.291C527.049 362.673 526.818 362.706 526.653 362.822C526.504 362.926 526.427 363.08 526.427 363.278ZM536.753 365.099C535.114 365.099 534.014 364.175 533.788 362.761L535.174 362.42C535.334 363.361 535.939 363.834 536.797 363.834C537.473 363.834 538.001 363.454 538.001 362.844C538.001 362.255 537.49 361.975 536.494 361.59C535.042 361.034 534.305 360.391 534.305 359.219C534.305 357.993 535.273 357.113 536.725 357.113C537.754 357.113 538.573 357.591 539.052 358.526L537.919 359.219C537.611 358.675 537.193 358.372 536.681 358.372C536.137 358.372 535.73 358.713 535.73 359.192C535.73 359.703 536.142 359.989 537.237 360.396C538.645 360.93 539.415 361.551 539.415 362.756C539.415 364.12 538.342 365.099 536.753 365.099ZM543.954 364.95L543.866 364.307C543.476 364.873 542.898 365.06 542.315 365.06C541.122 365.06 540.247 364.351 540.247 363.273C540.247 362.657 540.522 362.2 540.957 361.953C541.314 361.744 541.776 361.656 542.282 361.656H543.844V361.524C543.844 360.957 543.459 360.605 542.733 360.605C542.255 360.605 541.804 360.765 541.32 361.271L540.335 360.44C540.979 359.731 541.897 359.417 542.832 359.417C544.328 359.417 545.208 360.215 545.208 361.524V364.95H543.954ZM541.617 363.278C541.617 363.691 541.963 363.955 542.513 363.955C543.239 363.955 543.844 363.438 543.844 362.723V362.673H542.48C542.238 362.673 542.007 362.706 541.842 362.822C541.694 362.926 541.617 363.08 541.617 363.278ZM549.398 359.417C550.834 359.417 551.714 360.627 551.714 362.244C551.714 364.015 550.68 365.06 549.398 365.06C548.771 365.06 548.194 364.796 547.847 364.23V367.194H546.489V359.527H547.847V360.242C548.227 359.621 548.804 359.417 549.398 359.417ZM547.726 362.244C547.726 363.19 548.232 363.806 549.03 363.806C549.827 363.806 550.344 363.196 550.344 362.244C550.344 361.287 549.827 360.671 549.03 360.671C548.232 360.671 547.726 361.293 547.726 362.244ZM552.821 364.95V359.527H554.19V364.95H552.821ZM552.782 358.686V357.283H554.234V358.686H552.782ZM557.97 365.06C556.084 365.06 555.297 363.713 555.297 362.272C555.297 360.858 556.062 359.417 557.882 359.417C559.565 359.417 560.396 360.655 560.396 362.189C560.396 362.305 560.385 362.497 560.363 362.695H556.661C556.716 363.377 557.156 363.823 557.981 363.823C558.476 363.823 558.905 363.652 559.257 363.245L560.203 364.081C559.62 364.725 558.9 365.06 557.97 365.06ZM556.645 361.689H559.092V361.667C559.092 361.051 558.625 360.556 557.91 360.556C557.085 360.556 556.711 361.122 556.645 361.689ZM561.501 364.95V359.527H562.876V360.226C563.239 359.637 563.855 359.417 564.46 359.417C565.692 359.417 566.423 360.149 566.423 361.408V364.95H565.054V361.914C565.054 361.012 564.735 360.605 564.053 360.605C563.266 360.605 562.876 361.144 562.876 362.349V364.95H561.501ZM569.591 365.06C568.381 365.06 567.644 364.433 567.27 363.944L568.199 363.13C568.463 363.537 568.914 363.955 569.602 363.955C570.141 363.955 570.465 363.713 570.465 363.388C570.465 362.987 569.976 362.855 569.387 362.695C568.529 362.464 567.534 362.145 567.534 361.034C567.534 360.066 568.353 359.417 569.569 359.417C570.443 359.417 571.18 359.769 571.593 360.418L570.707 361.073C570.443 360.682 570.003 360.451 569.53 360.451C569.118 360.451 568.81 360.627 568.81 360.908C568.81 361.188 569.074 361.309 569.778 361.48C570.652 361.694 571.807 361.969 571.807 363.24C571.807 364.329 570.922 365.06 569.591 365.06Z" fill="black" /> <g class="al-2023-active-dots navy" id="active dots_7"> <circle id="Ellipse 2765_7" cx="578.374" cy="381.599" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_7" cx="578.375" cy="381.599" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_7" cx="578.375" cy="381.599" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive dot_7" cx="578.374" cy="381.599" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_7" cx="578.374" cy="381.599" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="14-OpenCell" data-milestone="opencell" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_27" d="M630.375 101.969V379.763" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_28" d="M630.923 380.565L678.548 380.565" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M610.658 359.886C608.48 359.886 606.995 358.291 606.995 355.893C606.995 353.484 608.48 351.889 610.658 351.889C612.847 351.889 614.321 353.484 614.321 355.893C614.321 358.291 612.836 359.886 610.658 359.886ZM610.658 358.577C612.055 358.577 612.946 357.543 612.946 355.893C612.946 354.232 612.055 353.198 610.658 353.198C609.261 353.198 608.37 354.221 608.37 355.893C608.37 357.554 609.261 358.577 610.658 358.577ZM618.404 354.188C619.878 354.188 620.692 355.387 620.692 357.015C620.692 358.786 619.735 359.831 618.404 359.831C617.788 359.831 617.183 359.578 616.842 359.171V361.965H615.522V354.298H616.842V354.837C617.216 354.375 617.821 354.188 618.404 354.188ZM618.074 358.676C618.954 358.676 619.372 358.06 619.372 357.004C619.372 355.937 618.965 355.343 618.085 355.343C617.128 355.343 616.721 356.036 616.721 357.004C616.721 357.95 617.128 358.676 618.074 358.676ZM626.437 356.938C626.437 357.103 626.426 357.268 626.404 357.444H622.686C622.741 358.159 623.181 358.632 624.039 358.632C624.523 358.632 624.963 358.478 625.337 358.049L626.25 358.852C625.656 359.512 624.941 359.831 624.028 359.831C622.158 359.831 621.366 358.489 621.366 357.037C621.366 355.618 622.136 354.188 623.94 354.188C625.623 354.188 626.437 355.431 626.437 356.938ZM622.675 356.399H625.172C625.15 355.706 624.622 355.288 623.929 355.288C623.126 355.288 622.752 355.86 622.675 356.399ZM630.48 354.188C631.701 354.188 632.394 354.936 632.394 356.223V359.721H631.074V356.553C631.074 356.179 631.074 355.343 630.073 355.343C628.841 355.343 628.841 356.586 628.841 357.554V359.721H627.521V354.298H628.841V354.925C629.226 354.408 629.82 354.188 630.48 354.188ZM639.857 359.886C637.591 359.886 636.139 358.335 636.139 355.882C636.139 353.429 637.591 351.878 639.857 351.878C641.474 351.878 642.695 352.659 643.256 354.122L641.991 354.617C641.65 353.66 640.902 353.187 639.857 353.187C638.372 353.187 637.514 354.155 637.514 355.871C637.514 357.598 638.383 358.577 639.857 358.577C640.913 358.577 641.661 358.082 641.991 357.114L643.278 357.598C642.728 359.083 641.496 359.886 639.857 359.886ZM648.727 356.938C648.727 357.103 648.716 357.268 648.694 357.444H644.976C645.031 358.159 645.471 358.632 646.329 358.632C646.813 358.632 647.253 358.478 647.627 358.049L648.54 358.852C647.946 359.512 647.231 359.831 646.318 359.831C644.448 359.831 643.656 358.489 643.656 357.037C643.656 355.618 644.426 354.188 646.23 354.188C647.913 354.188 648.727 355.431 648.727 356.938ZM644.965 356.399H647.462C647.44 355.706 646.912 355.288 646.219 355.288C645.416 355.288 645.042 355.86 644.965 356.399ZM651.032 359.831C650.295 359.831 649.756 359.391 649.756 358.423V352.054H651.076V358.335C651.076 358.577 651.219 358.676 651.461 358.676C651.582 358.676 651.725 358.654 651.879 358.61V359.666C651.582 359.776 651.285 359.831 651.032 359.831ZM654.094 359.831C653.357 359.831 652.818 359.391 652.818 358.423V352.054H654.138V358.335C654.138 358.577 654.281 358.676 654.523 358.676C654.644 358.676 654.787 358.654 654.941 358.61V359.666C654.644 359.776 654.347 359.831 654.094 359.831Z" fill="black" /> <g class="al-2023-active-dots navy" id="active dots_8"> <circle id="Ellipse 2765_8" cx="630.374" cy="379.972" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_8" cx="630.375" cy="379.972" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_8" cx="630.375" cy="379.972" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive dot_8" cx="630.374" cy="379.972" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_8" cx="630.374" cy="379.972" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="13-Chan-Zuckerberg-Institute-for-Advanced-Biological-Imaging" data-milestone="chan-zuckerberg-institute-for-advanced-biological-imaging" class="al-2023-svg-milestone"> <line class="al-2023-connector-line" id="connector-line_29" x1="728.938" y1="329.886" x2="681.615" y2="377.611" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M701.47 371.948C700.722 371.948 700.066 371.787 699.501 371.464C698.944 371.134 698.511 370.668 698.203 370.067C697.902 369.458 697.752 368.751 697.752 367.944C697.752 367.137 697.902 366.433 698.203 365.832C698.511 365.223 698.944 364.758 699.501 364.435C700.066 364.105 700.722 363.94 701.47 363.94C702.284 363.94 702.984 364.134 703.571 364.523C704.158 364.904 704.59 365.458 704.869 366.184L703.604 366.679C703.435 366.202 703.168 365.847 702.801 365.612C702.442 365.37 701.998 365.249 701.47 365.249C700.729 365.249 700.154 365.484 699.743 365.953C699.332 366.415 699.127 367.075 699.127 367.933C699.127 368.791 699.332 369.458 699.743 369.935C700.154 370.404 700.729 370.639 701.47 370.639C701.998 370.639 702.445 370.518 702.812 370.276C703.179 370.027 703.443 369.66 703.604 369.176L704.891 369.66C704.62 370.401 704.187 370.969 703.593 371.365C702.999 371.754 702.291 371.948 701.47 371.948ZM708.765 366.25C709.374 366.25 709.843 366.426 710.173 366.778C710.511 367.13 710.679 367.632 710.679 368.285V371.783H709.359V368.615C709.359 368.204 709.279 367.9 709.117 367.702C708.956 367.504 708.703 367.405 708.358 367.405C707.926 367.405 707.61 367.581 707.412 367.933C707.222 368.278 707.126 368.839 707.126 369.616V371.783H705.806V364.116H707.126V366.976C707.5 366.492 708.047 366.25 708.765 366.25ZM714.202 366.25C714.921 366.25 715.485 366.441 715.896 366.822C716.314 367.196 716.523 367.709 716.523 368.362V371.783H715.313L715.203 371.079C715.042 371.336 714.814 371.537 714.521 371.684C714.235 371.823 713.912 371.893 713.553 371.893C713.179 371.893 712.842 371.82 712.541 371.673C712.248 371.519 712.017 371.306 711.848 371.035C711.679 370.764 711.595 370.459 711.595 370.122C711.595 369.799 711.665 369.521 711.804 369.286C711.943 369.051 712.145 368.875 712.409 368.758C712.761 368.597 713.241 368.516 713.85 368.516H715.203V368.362C715.203 368.069 715.111 367.838 714.928 367.669C714.745 367.493 714.495 367.405 714.18 367.405C713.901 367.405 713.637 367.475 713.388 367.614C713.139 367.753 712.915 367.955 712.717 368.219L711.76 367.416C712.405 366.639 713.219 366.25 714.202 366.25ZM713.762 370.771C714.158 370.771 714.495 370.65 714.774 370.408C715.06 370.159 715.203 369.858 715.203 369.506H714.026C713.601 369.506 713.304 369.568 713.135 369.693C712.988 369.796 712.915 369.946 712.915 370.144C712.915 370.335 712.988 370.489 713.135 370.606C713.289 370.716 713.498 370.771 713.762 370.771ZM720.872 366.25C721.48 366.25 721.95 366.43 722.28 366.789C722.617 367.141 722.786 367.64 722.786 368.285V371.783H721.466V368.615C721.466 368.285 721.407 368.003 721.29 367.768C721.172 367.526 720.897 367.405 720.465 367.405C720.083 367.405 719.801 367.515 719.618 367.735C719.442 367.948 719.332 368.204 719.288 368.505C719.251 368.798 719.233 369.169 719.233 369.616V371.783H717.913V366.36H719.233V366.987C719.416 366.738 719.647 366.554 719.926 366.437C720.212 366.312 720.527 366.25 720.872 366.25ZM732.591 365.117L728.29 370.518H732.591V371.783H726.409V370.826L730.754 365.381H726.662V364.116H732.591V365.117ZM738.402 366.36V371.783H737.082V371.156C736.898 371.405 736.664 371.592 736.378 371.717C736.099 371.834 735.795 371.893 735.465 371.893C734.819 371.893 734.335 371.691 734.013 371.288C733.69 370.885 733.529 370.371 733.529 369.748V366.36H734.849V369.418C734.849 369.763 734.907 370.071 735.025 370.342C735.142 370.606 735.417 370.738 735.85 370.738C736.231 370.738 736.51 370.621 736.686 370.386C736.869 370.151 736.979 369.88 737.016 369.572C737.06 369.264 737.082 368.879 737.082 368.417V366.36H738.402ZM742.079 371.893C741.515 371.893 741.034 371.765 740.638 371.508C740.242 371.244 739.945 370.899 739.747 370.474C739.549 370.041 739.45 369.579 739.45 369.088C739.45 368.589 739.549 368.127 739.747 367.702C739.945 367.269 740.239 366.921 740.627 366.657C741.023 366.386 741.504 366.25 742.068 366.25C742.618 366.25 743.095 366.386 743.498 366.657C743.902 366.921 744.206 367.317 744.411 367.845L743.157 368.34C743.084 368.054 742.948 367.827 742.75 367.658C742.56 367.489 742.332 367.405 742.068 367.405C741.643 367.405 741.324 367.566 741.111 367.889C740.906 368.212 740.803 368.611 740.803 369.088C740.803 369.565 740.906 369.961 741.111 370.276C741.317 370.584 741.636 370.738 742.068 370.738C742.332 370.738 742.56 370.657 742.75 370.496C742.948 370.327 743.084 370.104 743.157 369.825L744.356 370.287C744.173 370.793 743.88 371.189 743.476 371.475C743.08 371.754 742.615 371.893 742.079 371.893ZM745.37 364.116H746.69V368.56L748.681 366.36H750.452L748.428 368.461L750.683 371.783H749.11L747.526 369.275L746.69 370.199V371.783H745.37V364.116ZM755.758 369C755.758 369.161 755.747 369.33 755.725 369.506H752.007C752.036 369.873 752.165 370.162 752.392 370.375C752.619 370.588 752.942 370.694 753.36 370.694C753.888 370.694 754.321 370.5 754.658 370.111L755.571 370.914C755.27 371.244 754.937 371.49 754.57 371.651C754.211 371.812 753.804 371.893 753.349 371.893C752.755 371.893 752.256 371.765 751.853 371.508C751.457 371.251 751.164 370.914 750.973 370.496C750.782 370.071 750.687 369.605 750.687 369.099C750.687 368.6 750.779 368.135 750.962 367.702C751.153 367.269 751.439 366.921 751.82 366.657C752.209 366.386 752.689 366.25 753.261 366.25C753.804 366.25 754.262 366.371 754.636 366.613C755.01 366.855 755.289 367.185 755.472 367.603C755.663 368.021 755.758 368.487 755.758 369ZM754.493 368.461C754.486 368.124 754.365 367.856 754.13 367.658C753.895 367.453 753.602 367.35 753.25 367.35C752.876 367.35 752.583 367.46 752.37 367.68C752.165 367.893 752.04 368.153 751.996 368.461H754.493ZM759.625 366.25C759.985 366.25 760.329 366.353 760.659 366.558L760.021 367.724C759.831 367.599 759.611 367.537 759.361 367.537C758.562 367.537 758.162 368.043 758.162 369.055V371.783H756.842V366.36H758.173V367.284C758.283 366.961 758.47 366.708 758.734 366.525C759.006 366.342 759.303 366.25 759.625 366.25ZM764.226 366.25C764.673 366.25 765.069 366.364 765.414 366.591C765.758 366.811 766.026 367.134 766.216 367.559C766.415 367.984 766.514 368.487 766.514 369.066C766.514 369.902 766.312 370.584 765.909 371.112C765.505 371.633 764.944 371.893 764.226 371.893C763.918 371.893 763.624 371.842 763.346 371.739C763.067 371.629 762.84 371.464 762.664 371.244V371.783H761.344V364.116H762.664V366.91C762.832 366.705 763.056 366.543 763.335 366.426C763.621 366.309 763.918 366.25 764.226 366.25ZM763.907 370.672C764.339 370.672 764.662 370.536 764.875 370.265C765.087 369.986 765.194 369.59 765.194 369.077C765.194 368.556 765.084 368.157 764.864 367.878C764.651 367.592 764.328 367.449 763.896 367.449C763.448 367.449 763.111 367.599 762.884 367.9C762.656 368.201 762.543 368.593 762.543 369.077C762.543 369.554 762.656 369.939 762.884 370.232C763.111 370.525 763.452 370.672 763.907 370.672ZM772.258 369C772.258 369.161 772.247 369.33 772.225 369.506H768.507C768.536 369.873 768.665 370.162 768.892 370.375C769.119 370.588 769.442 370.694 769.86 370.694C770.388 370.694 770.821 370.5 771.158 370.111L772.071 370.914C771.77 371.244 771.437 371.49 771.07 371.651C770.711 371.812 770.304 371.893 769.849 371.893C769.255 371.893 768.756 371.765 768.353 371.508C767.957 371.251 767.664 370.914 767.473 370.496C767.282 370.071 767.187 369.605 767.187 369.099C767.187 368.6 767.279 368.135 767.462 367.702C767.653 367.269 767.939 366.921 768.32 366.657C768.709 366.386 769.189 366.25 769.761 366.25C770.304 366.25 770.762 366.371 771.136 366.613C771.51 366.855 771.789 367.185 771.972 367.603C772.163 368.021 772.258 368.487 772.258 369ZM770.993 368.461C770.986 368.124 770.865 367.856 770.63 367.658C770.395 367.453 770.102 367.35 769.75 367.35C769.376 367.35 769.083 367.46 768.87 367.68C768.665 367.893 768.54 368.153 768.496 368.461H770.993ZM776.125 366.25C776.485 366.25 776.829 366.353 777.159 366.558L776.521 367.724C776.331 367.599 776.111 367.537 775.861 367.537C775.062 367.537 774.662 368.043 774.662 369.055V371.783H773.342V366.36H774.673V367.284C774.783 366.961 774.97 366.708 775.234 366.525C775.506 366.342 775.803 366.25 776.125 366.25ZM779.632 370.958C780.19 371.031 780.626 371.105 780.941 371.178C781.257 371.251 781.535 371.394 781.777 371.607C782.027 371.82 782.151 372.124 782.151 372.52C782.151 373.063 781.928 373.466 781.48 373.73C781.033 374.001 780.424 374.137 779.654 374.137C778.84 374.137 778.213 373.99 777.773 373.697C777.333 373.404 777.113 372.978 777.113 372.421C777.113 372.333 777.121 372.252 777.135 372.179L777.916 371.684C777.484 371.449 777.267 371.079 777.267 370.573C777.267 370.14 777.436 369.777 777.773 369.484C777.48 369.117 777.333 368.703 777.333 368.241C777.333 367.86 777.432 367.519 777.63 367.218C777.836 366.91 778.107 366.672 778.444 366.503C778.782 366.334 779.152 366.25 779.555 366.25C780.032 366.25 780.457 366.364 780.831 366.591L781.656 365.887L782.349 366.723L781.568 367.361C781.722 367.654 781.799 367.97 781.799 368.307C781.799 368.696 781.7 369.04 781.502 369.341C781.304 369.642 781.037 369.876 780.699 370.045C780.362 370.206 779.995 370.287 779.599 370.287C779.24 370.287 778.892 370.217 778.554 370.078C778.452 370.144 778.4 370.239 778.4 370.364C778.4 370.547 778.503 370.679 778.708 370.76C778.914 370.841 779.222 370.907 779.632 370.958ZM779.577 367.35C779.299 367.35 779.075 367.434 778.906 367.603C778.738 367.772 778.653 367.995 778.653 368.274C778.653 368.545 778.734 368.769 778.895 368.945C779.057 369.121 779.284 369.209 779.577 369.209C779.871 369.209 780.094 369.125 780.248 368.956C780.402 368.78 780.479 368.553 780.479 368.274C780.479 367.995 780.399 367.772 780.237 367.603C780.076 367.434 779.856 367.35 779.577 367.35ZM779.709 373.147C780.025 373.147 780.289 373.107 780.501 373.026C780.721 372.945 780.831 372.817 780.831 372.641C780.831 372.472 780.732 372.355 780.534 372.289C780.336 372.223 780.025 372.161 779.599 372.102L779.357 372.069L778.906 372.003L778.433 372.454C778.426 372.476 778.422 372.505 778.422 372.542C778.422 372.755 778.547 372.909 778.796 373.004C779.046 373.099 779.35 373.147 779.709 373.147ZM698.302 376.116H699.677V383.783H698.302V376.116ZM704.372 378.25C704.98 378.25 705.45 378.43 705.78 378.789C706.117 379.141 706.286 379.64 706.286 380.285V383.783H704.966V380.615C704.966 380.285 704.907 380.003 704.79 379.768C704.672 379.526 704.397 379.405 703.965 379.405C703.583 379.405 703.301 379.515 703.118 379.735C702.942 379.948 702.832 380.204 702.788 380.505C702.751 380.798 702.733 381.169 702.733 381.616V383.783H701.413V378.36H702.733V378.987C702.916 378.738 703.147 378.554 703.426 378.437C703.712 378.312 704.027 378.25 704.372 378.25ZM709.413 383.893C708.863 383.893 708.379 383.75 707.961 383.464C707.55 383.171 707.275 382.808 707.136 382.375L708.192 381.902C708.404 382.496 708.789 382.793 709.347 382.793C709.633 382.793 709.849 382.727 709.996 382.595C710.15 382.463 710.227 382.316 710.227 382.155C710.227 381.994 710.15 381.873 709.996 381.792C709.842 381.711 709.589 381.62 709.237 381.517C708.87 381.422 708.566 381.323 708.324 381.22C708.082 381.11 707.873 380.945 707.697 380.725C707.521 380.498 707.433 380.201 707.433 379.834C707.433 379.335 707.623 378.947 708.005 378.668C708.393 378.389 708.866 378.25 709.424 378.25C709.886 378.25 710.293 378.353 710.645 378.558C710.997 378.763 711.275 379.053 711.481 379.427L710.458 379.988C710.348 379.783 710.208 379.618 710.04 379.493C709.871 379.361 709.651 379.295 709.38 379.295C709.174 379.295 709.006 379.339 708.874 379.427C708.749 379.515 708.687 379.625 708.687 379.757C708.687 379.904 708.764 380.017 708.918 380.098C709.079 380.179 709.325 380.263 709.655 380.351C710.036 380.461 710.351 380.571 710.601 380.681C710.85 380.791 711.066 380.96 711.25 381.187C711.433 381.414 711.525 381.711 711.525 382.078C711.525 382.481 711.422 382.819 711.217 383.09C711.019 383.361 710.758 383.563 710.436 383.695C710.113 383.827 709.772 383.893 709.413 383.893ZM714.178 379.405V382.166C714.178 382.379 714.237 382.536 714.354 382.639C714.479 382.742 714.651 382.793 714.871 382.793C715.054 382.793 715.274 382.753 715.531 382.672V383.728C715.201 383.838 714.871 383.893 714.541 383.893C714.05 383.893 713.646 383.761 713.331 383.497C713.016 383.226 712.858 382.815 712.858 382.265V379.405H711.978V378.36H712.858V377.095L714.178 376.116V378.36H715.531V379.405H714.178ZM716.688 378.36H718.008V383.783H716.688V378.36ZM716.655 376.116H718.041V377.337H716.655V376.116ZM721.085 379.405V382.166C721.085 382.379 721.144 382.536 721.261 382.639C721.386 382.742 721.558 382.793 721.778 382.793C721.962 382.793 722.182 382.753 722.438 382.672V383.728C722.108 383.838 721.778 383.893 721.448 383.893C720.957 383.893 720.554 383.761 720.238 383.497C719.923 383.226 719.765 382.815 719.765 382.265V379.405H718.885V378.36H719.765V377.095L721.085 376.116V378.36H722.438V379.405H721.085ZM728.368 378.36V383.783H727.048V383.156C726.865 383.405 726.63 383.592 726.344 383.717C726.066 383.834 725.761 383.893 725.431 383.893C724.786 383.893 724.302 383.691 723.979 383.288C723.657 382.885 723.495 382.371 723.495 381.748V378.36H724.815V381.418C724.815 381.763 724.874 382.071 724.991 382.342C725.109 382.606 725.384 382.738 725.816 382.738C726.198 382.738 726.476 382.621 726.652 382.386C726.836 382.151 726.946 381.88 726.982 381.572C727.026 381.264 727.048 380.879 727.048 380.417V378.36H728.368ZM731.452 379.405V382.166C731.452 382.379 731.51 382.536 731.628 382.639C731.752 382.742 731.925 382.793 732.145 382.793C732.328 382.793 732.548 382.753 732.805 382.672V383.728C732.475 383.838 732.145 383.893 731.815 383.893C731.323 383.893 730.92 383.761 730.605 383.497C730.289 383.226 730.132 382.815 730.132 382.265V379.405H729.252V378.36H730.132V377.095L731.452 376.116V378.36H732.805V379.405H731.452ZM738.528 381C738.528 381.161 738.517 381.33 738.495 381.506H734.777C734.806 381.873 734.934 382.162 735.162 382.375C735.389 382.588 735.712 382.694 736.13 382.694C736.658 382.694 737.09 382.5 737.428 382.111L738.341 382.914C738.04 383.244 737.706 383.49 737.34 383.651C736.98 383.812 736.573 383.893 736.119 383.893C735.525 383.893 735.026 383.765 734.623 383.508C734.227 383.251 733.933 382.914 733.743 382.496C733.552 382.071 733.457 381.605 733.457 381.099C733.457 380.6 733.548 380.135 733.732 379.702C733.922 379.269 734.208 378.921 734.59 378.657C734.978 378.386 735.459 378.25 736.031 378.25C736.573 378.25 737.032 378.371 737.406 378.613C737.78 378.855 738.058 379.185 738.242 379.603C738.432 380.021 738.528 380.487 738.528 381ZM737.263 380.461C737.255 380.124 737.134 379.856 736.9 379.658C736.665 379.453 736.372 379.35 736.02 379.35C735.646 379.35 735.352 379.46 735.14 379.68C734.934 379.893 734.81 380.153 734.766 380.461H737.263ZM742.606 379.405H741.572V378.36H742.617V377.744C742.617 376.585 743.163 376.006 744.256 376.006C744.622 376.006 744.963 376.079 745.279 376.226L744.85 377.238C744.71 377.15 744.56 377.106 744.399 377.106C744.193 377.106 744.061 377.168 744.003 377.293C743.951 377.418 743.926 377.564 743.926 377.733V378.36H745.191V379.405H743.926V383.783H742.606V379.405ZM748.043 383.893C747.5 383.893 747.02 383.768 746.602 383.519C746.191 383.262 745.876 382.918 745.656 382.485C745.436 382.052 745.326 381.579 745.326 381.066C745.326 380.553 745.436 380.083 745.656 379.658C745.876 379.225 746.191 378.884 746.602 378.635C747.02 378.378 747.5 378.25 748.043 378.25C748.586 378.25 749.062 378.378 749.473 378.635C749.884 378.884 750.199 379.225 750.419 379.658C750.646 380.083 750.76 380.553 750.76 381.066C750.76 381.579 750.646 382.052 750.419 382.485C750.199 382.918 749.884 383.262 749.473 383.519C749.062 383.768 748.586 383.893 748.043 383.893ZM748.043 382.738C748.512 382.738 748.861 382.58 749.088 382.265C749.323 381.95 749.44 381.55 749.44 381.066C749.44 380.582 749.323 380.186 749.088 379.878C748.861 379.563 748.512 379.405 748.043 379.405C747.574 379.405 747.222 379.563 746.987 379.878C746.76 380.186 746.646 380.582 746.646 381.066C746.646 381.55 746.76 381.95 746.987 382.265C747.222 382.58 747.574 382.738 748.043 382.738ZM754.598 378.25C754.957 378.25 755.302 378.353 755.632 378.558L754.994 379.724C754.803 379.599 754.583 379.537 754.334 379.537C753.535 379.537 753.135 380.043 753.135 381.055V383.783H751.815V378.36H753.146V379.284C753.256 378.961 753.443 378.708 753.707 378.525C753.978 378.342 754.275 378.25 754.598 378.25ZM763.304 382.199H760.301L759.718 383.783H758.222L761.291 376.116H762.325L765.383 383.783H763.887L763.304 382.199ZM762.842 380.934L761.808 378.14L760.774 380.934H762.842ZM770.843 376.116V383.783H769.523V383.244C769.347 383.464 769.12 383.629 768.841 383.739C768.563 383.842 768.269 383.893 767.961 383.893C767.243 383.893 766.682 383.633 766.278 383.112C765.875 382.584 765.673 381.902 765.673 381.066C765.673 380.487 765.769 379.984 765.959 379.559C766.157 379.134 766.429 378.811 766.773 378.591C767.118 378.364 767.514 378.25 767.961 378.25C768.269 378.25 768.563 378.309 768.841 378.426C769.127 378.543 769.355 378.705 769.523 378.91V376.116H770.843ZM768.28 382.672C768.735 382.672 769.076 382.525 769.303 382.232C769.531 381.939 769.644 381.554 769.644 381.077C769.644 380.593 769.531 380.201 769.303 379.9C769.076 379.599 768.739 379.449 768.291 379.449C767.859 379.449 767.532 379.592 767.312 379.878C767.1 380.157 766.993 380.556 766.993 381.077C766.993 381.59 767.1 381.986 767.312 382.265C767.525 382.536 767.848 382.672 768.28 382.672ZM771.572 378.36H773.013L774.322 382.067L775.653 378.36H777.083L774.872 383.783H773.783L771.572 378.36ZM779.88 378.25C780.598 378.25 781.163 378.441 781.574 378.822C781.992 379.196 782.201 379.709 782.201 380.362V383.783H780.991L780.881 383.079C780.719 383.336 780.492 383.537 780.199 383.684C779.913 383.823 779.59 383.893 779.231 383.893C778.857 383.893 778.519 383.82 778.219 383.673C777.925 383.519 777.694 383.306 777.526 383.035C777.357 382.764 777.273 382.459 777.273 382.122C777.273 381.799 777.342 381.521 777.482 381.286C777.621 381.051 777.823 380.875 778.087 380.758C778.439 380.597 778.919 380.516 779.528 380.516H780.881V380.362C780.881 380.069 780.789 379.838 780.606 379.669C780.422 379.493 780.173 379.405 779.858 379.405C779.579 379.405 779.315 379.475 779.066 379.614C778.816 379.753 778.593 379.955 778.395 380.219L777.438 379.416C778.083 378.639 778.897 378.25 779.88 378.25ZM779.44 382.771C779.836 382.771 780.173 382.65 780.452 382.408C780.738 382.159 780.881 381.858 780.881 381.506H779.704C779.278 381.506 778.981 381.568 778.813 381.693C778.666 381.796 778.593 381.946 778.593 382.144C778.593 382.335 778.666 382.489 778.813 382.606C778.967 382.716 779.176 382.771 779.44 382.771ZM786.549 378.25C787.158 378.25 787.627 378.43 787.957 378.789C788.295 379.141 788.463 379.64 788.463 380.285V383.783H787.143V380.615C787.143 380.285 787.085 380.003 786.967 379.768C786.85 379.526 786.575 379.405 786.142 379.405C785.761 379.405 785.479 379.515 785.295 379.735C785.119 379.948 785.009 380.204 784.965 380.505C784.929 380.798 784.91 381.169 784.91 381.616V383.783H783.59V378.36H784.91V378.987C785.094 378.738 785.325 378.554 785.603 378.437C785.889 378.312 786.205 378.25 786.549 378.25ZM792.041 383.893C791.477 383.893 790.996 383.765 790.6 383.508C790.204 383.244 789.907 382.899 789.709 382.474C789.511 382.041 789.412 381.579 789.412 381.088C789.412 380.589 789.511 380.127 789.709 379.702C789.907 379.269 790.201 378.921 790.589 378.657C790.985 378.386 791.466 378.25 792.03 378.25C792.58 378.25 793.057 378.386 793.46 378.657C793.864 378.921 794.168 379.317 794.373 379.845L793.119 380.34C793.046 380.054 792.91 379.827 792.712 379.658C792.522 379.489 792.294 379.405 792.03 379.405C791.605 379.405 791.286 379.566 791.073 379.889C790.868 380.212 790.765 380.611 790.765 381.088C790.765 381.565 790.868 381.961 791.073 382.276C791.279 382.584 791.598 382.738 792.03 382.738C792.294 382.738 792.522 382.657 792.712 382.496C792.91 382.327 793.046 382.104 793.119 381.825L794.318 382.287C794.135 382.793 793.842 383.189 793.438 383.475C793.042 383.754 792.577 383.893 792.041 383.893ZM799.887 381C799.887 381.161 799.876 381.33 799.854 381.506H796.136C796.165 381.873 796.294 382.162 796.521 382.375C796.748 382.588 797.071 382.694 797.489 382.694C798.017 382.694 798.45 382.5 798.787 382.111L799.7 382.914C799.399 383.244 799.066 383.49 798.699 383.651C798.34 383.812 797.933 383.893 797.478 383.893C796.884 383.893 796.385 383.765 795.982 383.508C795.586 383.251 795.293 382.914 795.102 382.496C794.911 382.071 794.816 381.605 794.816 381.099C794.816 380.6 794.908 380.135 795.091 379.702C795.282 379.269 795.568 378.921 795.949 378.657C796.338 378.386 796.818 378.25 797.39 378.25C797.933 378.25 798.391 378.371 798.765 378.613C799.139 378.855 799.418 379.185 799.601 379.603C799.792 380.021 799.887 380.487 799.887 381ZM798.622 380.461C798.615 380.124 798.494 379.856 798.259 379.658C798.024 379.453 797.731 379.35 797.379 379.35C797.005 379.35 796.712 379.46 796.499 379.68C796.294 379.893 796.169 380.153 796.125 380.461H798.622ZM805.723 376.116V383.783H804.403V383.244C804.227 383.464 804 383.629 803.721 383.739C803.443 383.842 803.149 383.893 802.841 383.893C802.123 383.893 801.562 383.633 801.158 383.112C800.755 382.584 800.553 381.902 800.553 381.066C800.553 380.487 800.649 379.984 800.839 379.559C801.037 379.134 801.309 378.811 801.653 378.591C801.998 378.364 802.394 378.25 802.841 378.25C803.149 378.25 803.443 378.309 803.721 378.426C804.007 378.543 804.235 378.705 804.403 378.91V376.116H805.723ZM803.16 382.672C803.615 382.672 803.956 382.525 804.183 382.232C804.411 381.939 804.524 381.554 804.524 381.077C804.524 380.593 804.411 380.201 804.183 379.9C803.956 379.599 803.619 379.449 803.171 379.449C802.739 379.449 802.412 379.592 802.192 379.878C801.98 380.157 801.873 380.556 801.873 381.077C801.873 381.59 801.98 381.986 802.192 382.265C802.405 382.536 802.728 382.672 803.16 382.672ZM698.302 388.116H700.975C701.738 388.116 702.332 388.288 702.757 388.633C703.19 388.97 703.406 389.443 703.406 390.052C703.406 390.411 703.333 390.73 703.186 391.009C703.039 391.28 702.83 391.493 702.559 391.647C703.395 391.948 703.813 392.578 703.813 393.539C703.813 394.243 703.593 394.793 703.153 395.189C702.713 395.585 702.101 395.783 701.316 395.783H698.302V388.116ZM700.975 391.163C701.32 391.163 701.58 391.09 701.756 390.943C701.939 390.796 702.031 390.58 702.031 390.294C702.031 390.001 701.939 389.777 701.756 389.623C701.573 389.462 701.312 389.381 700.975 389.381H699.677V391.163H700.975ZM701.206 394.518C701.587 394.518 701.888 394.423 702.108 394.232C702.328 394.034 702.438 393.766 702.438 393.429C702.438 393.106 702.332 392.861 702.119 392.692C701.914 392.516 701.609 392.428 701.206 392.428H699.677V394.518H701.206ZM705.022 390.36H706.342V395.783H705.022V390.36ZM704.989 388.116H706.375V389.337H704.989V388.116ZM710.112 395.893C709.57 395.893 709.089 395.768 708.671 395.519C708.261 395.262 707.945 394.918 707.725 394.485C707.505 394.052 707.395 393.579 707.395 393.066C707.395 392.553 707.505 392.083 707.725 391.658C707.945 391.225 708.261 390.884 708.671 390.635C709.089 390.378 709.57 390.25 710.112 390.25C710.655 390.25 711.132 390.378 711.542 390.635C711.953 390.884 712.268 391.225 712.488 391.658C712.716 392.083 712.829 392.553 712.829 393.066C712.829 393.579 712.716 394.052 712.488 394.485C712.268 394.918 711.953 395.262 711.542 395.519C711.132 395.768 710.655 395.893 710.112 395.893ZM710.112 394.738C710.582 394.738 710.93 394.58 711.157 394.265C711.392 393.95 711.509 393.55 711.509 393.066C711.509 392.582 711.392 392.186 711.157 391.878C710.93 391.563 710.582 391.405 710.112 391.405C709.643 391.405 709.291 391.563 709.056 391.878C708.829 392.186 708.715 392.582 708.715 393.066C708.715 393.55 708.829 393.95 709.056 394.265C709.291 394.58 709.643 394.738 710.112 394.738ZM715.105 395.893C714.717 395.893 714.405 395.776 714.17 395.541C713.943 395.306 713.829 394.954 713.829 394.485V388.116H715.149V394.397C715.149 394.624 715.278 394.738 715.534 394.738C715.659 394.738 715.798 394.716 715.952 394.672V395.728C715.659 395.838 715.377 395.893 715.105 395.893ZM719.179 395.893C718.636 395.893 718.156 395.768 717.738 395.519C717.327 395.262 717.012 394.918 716.792 394.485C716.572 394.052 716.462 393.579 716.462 393.066C716.462 392.553 716.572 392.083 716.792 391.658C717.012 391.225 717.327 390.884 717.738 390.635C718.156 390.378 718.636 390.25 719.179 390.25C719.721 390.25 720.198 390.378 720.609 390.635C721.019 390.884 721.335 391.225 721.555 391.658C721.782 392.083 721.896 392.553 721.896 393.066C721.896 393.579 721.782 394.052 721.555 394.485C721.335 394.918 721.019 395.262 720.609 395.519C720.198 395.768 719.721 395.893 719.179 395.893ZM719.179 394.738C719.648 394.738 719.996 394.58 720.224 394.265C720.458 393.95 720.576 393.55 720.576 393.066C720.576 392.582 720.458 392.186 720.224 391.878C719.996 391.563 719.648 391.405 719.179 391.405C718.709 391.405 718.357 391.563 718.123 391.878C717.895 392.186 717.782 392.582 717.782 393.066C717.782 393.55 717.895 393.95 718.123 394.265C718.357 394.58 718.709 394.738 719.179 394.738ZM725.03 394.958C725.587 395.031 726.023 395.105 726.339 395.178C726.654 395.251 726.933 395.394 727.175 395.607C727.424 395.82 727.549 396.124 727.549 396.52C727.549 397.063 727.325 397.466 726.878 397.73C726.43 398.001 725.822 398.137 725.052 398.137C724.238 398.137 723.611 397.99 723.171 397.697C722.731 397.404 722.511 396.978 722.511 396.421C722.511 396.333 722.518 396.252 722.533 396.179L723.314 395.684C722.881 395.449 722.665 395.079 722.665 394.573C722.665 394.14 722.833 393.777 723.171 393.484C722.877 393.117 722.731 392.703 722.731 392.241C722.731 391.86 722.83 391.519 723.028 391.218C723.233 390.91 723.504 390.672 723.842 390.503C724.179 390.334 724.549 390.25 724.953 390.25C725.429 390.25 725.855 390.364 726.229 390.591L727.054 389.887L727.747 390.723L726.966 391.361C727.12 391.654 727.197 391.97 727.197 392.307C727.197 392.696 727.098 393.04 726.9 393.341C726.702 393.642 726.434 393.876 726.097 394.045C725.759 394.206 725.393 394.287 724.997 394.287C724.637 394.287 724.289 394.217 723.952 394.078C723.849 394.144 723.798 394.239 723.798 394.364C723.798 394.547 723.9 394.679 724.106 394.76C724.311 394.841 724.619 394.907 725.03 394.958ZM724.975 391.35C724.696 391.35 724.472 391.434 724.304 391.603C724.135 391.772 724.051 391.995 724.051 392.274C724.051 392.545 724.131 392.769 724.293 392.945C724.454 393.121 724.681 393.209 724.975 393.209C725.268 393.209 725.492 393.125 725.646 392.956C725.8 392.78 725.877 392.553 725.877 392.274C725.877 391.995 725.796 391.772 725.635 391.603C725.473 391.434 725.253 391.35 724.975 391.35ZM725.107 397.147C725.422 397.147 725.686 397.107 725.899 397.026C726.119 396.945 726.229 396.817 726.229 396.641C726.229 396.472 726.13 396.355 725.932 396.289C725.734 396.223 725.422 396.161 724.997 396.102L724.755 396.069L724.304 396.003L723.831 396.454C723.823 396.476 723.82 396.505 723.82 396.542C723.82 396.755 723.944 396.909 724.194 397.004C724.443 397.099 724.747 397.147 725.107 397.147ZM728.601 390.36H729.921V395.783H728.601V390.36ZM728.568 388.116H729.954V389.337H728.568V388.116ZM733.614 395.893C733.05 395.893 732.569 395.765 732.173 395.508C731.777 395.244 731.48 394.899 731.282 394.474C731.084 394.041 730.985 393.579 730.985 393.088C730.985 392.589 731.084 392.127 731.282 391.702C731.48 391.269 731.774 390.921 732.162 390.657C732.558 390.386 733.039 390.25 733.603 390.25C734.153 390.25 734.63 390.386 735.033 390.657C735.437 390.921 735.741 391.317 735.946 391.845L734.692 392.34C734.619 392.054 734.483 391.827 734.285 391.658C734.095 391.489 733.867 391.405 733.603 391.405C733.178 391.405 732.859 391.566 732.646 391.889C732.441 392.212 732.338 392.611 732.338 393.088C732.338 393.565 732.441 393.961 732.646 394.276C732.852 394.584 733.171 394.738 733.603 394.738C733.867 394.738 734.095 394.657 734.285 394.496C734.483 394.327 734.619 394.104 734.692 393.825L735.891 394.287C735.708 394.793 735.415 395.189 735.011 395.475C734.615 395.754 734.15 395.893 733.614 395.893ZM738.974 390.25C739.692 390.25 740.257 390.441 740.668 390.822C741.086 391.196 741.295 391.709 741.295 392.362V395.783H740.085L739.975 395.079C739.813 395.336 739.586 395.537 739.293 395.684C739.007 395.823 738.684 395.893 738.325 395.893C737.951 395.893 737.613 395.82 737.313 395.673C737.019 395.519 736.788 395.306 736.62 395.035C736.451 394.764 736.367 394.459 736.367 394.122C736.367 393.799 736.436 393.521 736.576 393.286C736.715 393.051 736.917 392.875 737.181 392.758C737.533 392.597 738.013 392.516 738.622 392.516H739.975V392.362C739.975 392.069 739.883 391.838 739.7 391.669C739.516 391.493 739.267 391.405 738.952 391.405C738.673 391.405 738.409 391.475 738.16 391.614C737.91 391.753 737.687 391.955 737.489 392.219L736.532 391.416C737.177 390.639 737.991 390.25 738.974 390.25ZM738.534 394.771C738.93 394.771 739.267 394.65 739.546 394.408C739.832 394.159 739.975 393.858 739.975 393.506H738.798C738.372 393.506 738.075 393.568 737.907 393.693C737.76 393.796 737.687 393.946 737.687 394.144C737.687 394.335 737.76 394.489 737.907 394.606C738.061 394.716 738.27 394.771 738.534 394.771ZM743.905 395.893C743.516 395.893 743.205 395.776 742.97 395.541C742.743 395.306 742.629 394.954 742.629 394.485V388.116H743.949V394.397C743.949 394.624 744.077 394.738 744.334 394.738C744.459 394.738 744.598 394.716 744.752 394.672V395.728C744.459 395.838 744.176 395.893 743.905 395.893ZM748.618 388.116H749.993V395.783H748.618V388.116ZM757.79 390.25C758.406 390.25 758.875 390.452 759.198 390.855C759.521 391.251 759.682 391.742 759.682 392.329V395.783H758.362V392.725C758.362 391.845 758.054 391.405 757.438 391.405C757.093 391.405 756.844 391.515 756.69 391.735C756.536 391.948 756.444 392.201 756.415 392.494C756.386 392.78 756.371 393.187 756.371 393.715V395.783H755.051V392.725C755.051 391.845 754.747 391.405 754.138 391.405C753.793 391.405 753.544 391.515 753.39 391.735C753.236 391.948 753.141 392.204 753.104 392.505C753.075 392.798 753.06 393.202 753.06 393.715V395.783H751.74L751.729 390.36H753.005V391.042C753.313 390.514 753.797 390.25 754.457 390.25C754.794 390.25 755.102 390.331 755.381 390.492C755.667 390.653 755.887 390.928 756.041 391.317C756.239 390.936 756.485 390.664 756.778 390.503C757.071 390.334 757.409 390.25 757.79 390.25ZM763.186 390.25C763.905 390.25 764.47 390.441 764.88 390.822C765.298 391.196 765.507 391.709 765.507 392.362V395.783H764.297L764.187 395.079C764.026 395.336 763.799 395.537 763.505 395.684C763.219 395.823 762.897 395.893 762.537 395.893C762.163 395.893 761.826 395.82 761.525 395.673C761.232 395.519 761.001 395.306 760.832 395.035C760.664 394.764 760.579 394.459 760.579 394.122C760.579 393.799 760.649 393.521 760.788 393.286C760.928 393.051 761.129 392.875 761.393 392.758C761.745 392.597 762.226 392.516 762.834 392.516H764.187V392.362C764.187 392.069 764.096 391.838 763.912 391.669C763.729 391.493 763.48 391.405 763.164 391.405C762.886 391.405 762.622 391.475 762.372 391.614C762.123 391.753 761.899 391.955 761.701 392.219L760.744 391.416C761.39 390.639 762.204 390.25 763.186 390.25ZM762.746 394.771C763.142 394.771 763.48 394.65 763.758 394.408C764.044 394.159 764.187 393.858 764.187 393.506H763.01C762.585 393.506 762.288 393.568 762.119 393.693C761.973 393.796 761.899 393.946 761.899 394.144C761.899 394.335 761.973 394.489 762.119 394.606C762.273 394.716 762.482 394.771 762.746 394.771ZM768.954 394.958C769.512 395.031 769.948 395.105 770.263 395.178C770.579 395.251 770.857 395.394 771.099 395.607C771.349 395.82 771.473 396.124 771.473 396.52C771.473 397.063 771.25 397.466 770.802 397.73C770.355 398.001 769.746 398.137 768.976 398.137C768.162 398.137 767.535 397.99 767.095 397.697C766.655 397.404 766.435 396.978 766.435 396.421C766.435 396.333 766.443 396.252 766.457 396.179L767.238 395.684C766.806 395.449 766.589 395.079 766.589 394.573C766.589 394.14 766.758 393.777 767.095 393.484C766.802 393.117 766.655 392.703 766.655 392.241C766.655 391.86 766.754 391.519 766.952 391.218C767.158 390.91 767.429 390.672 767.766 390.503C768.104 390.334 768.474 390.25 768.877 390.25C769.354 390.25 769.779 390.364 770.153 390.591L770.978 389.887L771.671 390.723L770.89 391.361C771.044 391.654 771.121 391.97 771.121 392.307C771.121 392.696 771.022 393.04 770.824 393.341C770.626 393.642 770.359 393.876 770.021 394.045C769.684 394.206 769.317 394.287 768.921 394.287C768.562 394.287 768.214 394.217 767.876 394.078C767.774 394.144 767.722 394.239 767.722 394.364C767.722 394.547 767.825 394.679 768.03 394.76C768.236 394.841 768.544 394.907 768.954 394.958ZM768.899 391.35C768.621 391.35 768.397 391.434 768.228 391.603C768.06 391.772 767.975 391.995 767.975 392.274C767.975 392.545 768.056 392.769 768.217 392.945C768.379 393.121 768.606 393.209 768.899 393.209C769.193 393.209 769.416 393.125 769.57 392.956C769.724 392.78 769.801 392.553 769.801 392.274C769.801 391.995 769.721 391.772 769.559 391.603C769.398 391.434 769.178 391.35 768.899 391.35ZM769.031 397.147C769.347 397.147 769.611 397.107 769.823 397.026C770.043 396.945 770.153 396.817 770.153 396.641C770.153 396.472 770.054 396.355 769.856 396.289C769.658 396.223 769.347 396.161 768.921 396.102L768.679 396.069L768.228 396.003L767.755 396.454C767.748 396.476 767.744 396.505 767.744 396.542C767.744 396.755 767.869 396.909 768.118 397.004C768.368 397.099 768.672 397.147 769.031 397.147ZM772.526 390.36H773.846V395.783H772.526V390.36ZM772.493 388.116H773.879V389.337H772.493V388.116ZM778.342 390.25C778.951 390.25 779.42 390.43 779.75 390.789C780.088 391.141 780.256 391.64 780.256 392.285V395.783H778.936V392.615C778.936 392.285 778.878 392.003 778.76 391.768C778.643 391.526 778.368 391.405 777.935 391.405C777.554 391.405 777.272 391.515 777.088 391.735C776.912 391.948 776.802 392.204 776.758 392.505C776.722 392.798 776.703 393.169 776.703 393.616V395.783H775.383V390.36H776.703V390.987C776.887 390.738 777.118 390.554 777.396 390.437C777.682 390.312 777.998 390.25 778.342 390.25ZM783.757 394.958C784.315 395.031 784.751 395.105 785.066 395.178C785.382 395.251 785.66 395.394 785.902 395.607C786.152 395.82 786.276 396.124 786.276 396.52C786.276 397.063 786.053 397.466 785.605 397.73C785.158 398.001 784.549 398.137 783.779 398.137C782.965 398.137 782.338 397.99 781.898 397.697C781.458 397.404 781.238 396.978 781.238 396.421C781.238 396.333 781.246 396.252 781.26 396.179L782.041 395.684C781.609 395.449 781.392 395.079 781.392 394.573C781.392 394.14 781.561 393.777 781.898 393.484C781.605 393.117 781.458 392.703 781.458 392.241C781.458 391.86 781.557 391.519 781.755 391.218C781.961 390.91 782.232 390.672 782.569 390.503C782.907 390.334 783.277 390.25 783.68 390.25C784.157 390.25 784.582 390.364 784.956 390.591L785.781 389.887L786.474 390.723L785.693 391.361C785.847 391.654 785.924 391.97 785.924 392.307C785.924 392.696 785.825 393.04 785.627 393.341C785.429 393.642 785.162 393.876 784.824 394.045C784.487 394.206 784.12 394.287 783.724 394.287C783.365 394.287 783.017 394.217 782.679 394.078C782.577 394.144 782.525 394.239 782.525 394.364C782.525 394.547 782.628 394.679 782.833 394.76C783.039 394.841 783.347 394.907 783.757 394.958ZM783.702 391.35C783.424 391.35 783.2 391.434 783.031 391.603C782.863 391.772 782.778 391.995 782.778 392.274C782.778 392.545 782.859 392.769 783.02 392.945C783.182 393.121 783.409 393.209 783.702 393.209C783.996 393.209 784.219 393.125 784.373 392.956C784.527 392.78 784.604 392.553 784.604 392.274C784.604 391.995 784.524 391.772 784.362 391.603C784.201 391.434 783.981 391.35 783.702 391.35ZM783.834 397.147C784.15 397.147 784.414 397.107 784.626 397.026C784.846 396.945 784.956 396.817 784.956 396.641C784.956 396.472 784.857 396.355 784.659 396.289C784.461 396.223 784.15 396.161 783.724 396.102L783.482 396.069L783.031 396.003L782.558 396.454C782.551 396.476 782.547 396.505 782.547 396.542C782.547 396.755 782.672 396.909 782.921 397.004C783.171 397.099 783.475 397.147 783.834 397.147Z" fill="black" /> <g class="al-2023-active-dots navy" id="active dots_9"> <circle id="Ellipse 2765_9" cx="679.256" cy="379.972" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_9" cx="679.256" cy="379.972" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_9" cx="679.256" cy="379.972" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive dot_9" cx="679.256" cy="379.972" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_9" cx="679.256" cy="379.972" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="12-Chan-Zuckerberg-Biohub-Network" data-milestone="chan-zuckerberg-biohub-network" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_30" d="M630.375 101.969L727.551 334.782" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M751.077 336.679C748.811 336.679 747.359 335.128 747.359 332.675C747.359 330.222 748.811 328.671 751.077 328.671C752.694 328.671 753.915 329.452 754.476 330.915L753.211 331.41C752.87 330.453 752.122 329.98 751.077 329.98C749.592 329.98 748.734 330.948 748.734 332.664C748.734 334.391 749.603 335.37 751.077 335.37C752.133 335.37 752.881 334.875 753.211 333.907L754.498 334.391C753.948 335.876 752.716 336.679 751.077 336.679ZM758.373 330.981C759.594 330.981 760.287 331.718 760.287 333.016V336.514H758.967V333.346C758.967 332.521 758.648 332.136 757.966 332.136C757.097 332.136 756.734 332.785 756.734 334.347V336.514H755.414V328.847H756.734V331.707C757.097 331.234 757.658 330.981 758.373 330.981ZM763.809 330.981C765.239 330.981 766.13 331.784 766.13 333.093V336.514H764.92L764.81 335.81C764.491 336.316 763.875 336.624 763.16 336.624C762.016 336.624 761.202 335.887 761.202 334.853C761.202 334.215 761.488 333.731 762.016 333.489C762.379 333.324 762.841 333.247 763.457 333.247H764.81V333.093C764.81 332.499 764.414 332.136 763.787 332.136C763.237 332.136 762.72 332.422 762.324 332.95L761.367 332.147C762.016 331.366 762.819 330.981 763.809 330.981ZM763.369 335.502C764.161 335.502 764.81 334.941 764.81 334.237H763.633C763.182 334.237 762.918 334.292 762.742 334.424C762.599 334.523 762.522 334.677 762.522 334.875C762.522 335.26 762.841 335.502 763.369 335.502ZM770.479 330.981C771.7 330.981 772.393 331.729 772.393 333.016V336.514H771.073V333.346C771.073 332.972 771.073 332.136 770.072 332.136C768.84 332.136 768.84 333.379 768.84 334.347V336.514H767.52V331.091H768.84V331.718C769.225 331.201 769.819 330.981 770.479 330.981ZM782.199 328.847V329.848L777.898 335.249H782.199V336.514H776.017V335.557L780.362 330.112H776.27V328.847H782.199ZM786.689 331.091H788.009V336.514H786.689V335.887C786.304 336.404 785.71 336.624 785.072 336.624C783.708 336.624 783.136 335.634 783.136 334.479V331.091H784.456V334.149C784.456 334.523 784.456 335.469 785.457 335.469C786.689 335.469 786.689 334.116 786.689 333.148V331.091ZM791.687 336.624C789.916 336.624 789.058 335.249 789.058 333.819C789.058 332.389 789.905 330.981 791.676 330.981C792.754 330.981 793.601 331.498 794.019 332.576L792.765 333.071C792.622 332.499 792.215 332.136 791.676 332.136C790.763 332.136 790.411 332.961 790.411 333.819C790.411 334.677 790.752 335.469 791.676 335.469C792.204 335.469 792.622 335.117 792.765 334.556L793.964 335.018C793.601 336.03 792.765 336.624 791.687 336.624ZM794.977 336.514V328.847H796.297V333.291L798.288 331.091H800.059L798.035 333.192L800.29 336.514H798.717L797.133 334.006L796.297 334.93V336.514H794.977ZM805.366 333.731C805.366 333.896 805.355 334.061 805.333 334.237H801.615C801.67 334.952 802.11 335.425 802.968 335.425C803.452 335.425 803.892 335.271 804.266 334.842L805.179 335.645C804.585 336.305 803.87 336.624 802.957 336.624C801.087 336.624 800.295 335.282 800.295 333.83C800.295 332.411 801.065 330.981 802.869 330.981C804.552 330.981 805.366 332.224 805.366 333.731ZM801.604 333.192H804.101C804.079 332.499 803.551 332.081 802.858 332.081C802.055 332.081 801.681 332.653 801.604 333.192ZM809.233 330.981C809.596 330.981 809.915 331.069 810.267 331.289L809.629 332.455C809.442 332.334 809.233 332.268 808.969 332.268C808.166 332.268 807.77 332.763 807.77 333.786V336.514H806.45V331.091H807.781V332.015C808.012 331.344 808.617 330.981 809.233 330.981ZM813.833 330.981C815.164 330.981 816.121 332.026 816.121 333.797C816.121 335.425 815.307 336.624 813.833 336.624C813.25 336.624 812.645 336.437 812.271 335.975V336.514H810.951V328.847H812.271V331.641C812.612 331.234 813.217 330.981 813.833 330.981ZM813.514 335.403C814.394 335.403 814.801 334.809 814.801 333.808C814.801 332.796 814.383 332.18 813.503 332.18C812.557 332.18 812.15 332.906 812.15 333.808C812.15 334.71 812.557 335.403 813.514 335.403ZM821.866 333.731C821.866 333.896 821.855 334.061 821.833 334.237H818.115C818.17 334.952 818.61 335.425 819.468 335.425C819.952 335.425 820.392 335.271 820.766 334.842L821.679 335.645C821.085 336.305 820.37 336.624 819.457 336.624C817.587 336.624 816.795 335.282 816.795 333.83C816.795 332.411 817.565 330.981 819.369 330.981C821.052 330.981 821.866 332.224 821.866 333.731ZM818.104 333.192H820.601C820.579 332.499 820.051 332.081 819.358 332.081C818.555 332.081 818.181 332.653 818.104 333.192ZM825.733 330.981C826.096 330.981 826.415 331.069 826.767 331.289L826.129 332.455C825.942 332.334 825.733 332.268 825.469 332.268C824.666 332.268 824.27 332.763 824.27 333.786V336.514H822.95V331.091H824.281V332.015C824.512 331.344 825.117 330.981 825.733 330.981ZM829.24 335.689C830.34 335.832 831.759 335.953 831.759 337.251C831.759 338.384 830.725 338.868 829.262 338.868C827.645 338.868 826.721 338.274 826.721 337.152C826.721 337.02 826.732 336.965 826.743 336.91L827.524 336.415C827.139 336.206 826.875 335.865 826.875 335.304C826.875 334.831 827.062 334.49 827.381 334.215C827.106 333.874 826.941 333.445 826.941 332.972C826.941 331.795 827.953 330.981 829.163 330.981C829.636 330.981 830.076 331.102 830.439 331.322L831.264 330.618L831.957 331.454L831.176 332.092C831.319 332.367 831.407 332.686 831.407 333.038C831.407 334.248 830.395 335.018 829.207 335.018C828.833 335.018 828.481 334.941 828.162 334.809C828.063 334.875 828.008 334.963 828.008 335.095C828.008 335.491 828.558 335.601 829.24 335.689ZM829.185 332.081C828.624 332.081 828.261 332.455 828.261 333.005C828.261 333.522 828.569 333.94 829.185 333.94C829.79 333.94 830.087 333.533 830.087 333.005C830.087 332.444 829.746 332.081 829.185 332.081ZM829.317 337.878C829.878 337.878 830.439 337.746 830.439 337.372C830.439 336.954 829.746 336.91 828.965 336.8L828.514 336.734L828.041 337.185C828.03 337.218 828.03 337.251 828.03 337.273C828.03 337.735 828.701 337.878 829.317 337.878ZM747.909 348.514V340.847H750.582C752.111 340.847 753.013 341.573 753.013 342.783C753.013 343.498 752.705 344.07 752.166 344.378C752.991 344.675 753.42 345.313 753.42 346.27C753.42 347.678 752.485 348.514 750.923 348.514H747.909ZM749.284 343.894H750.582C751.275 343.894 751.638 343.597 751.638 343.025C751.638 342.442 751.253 342.112 750.582 342.112H749.284V343.894ZM749.284 347.249H750.813C751.583 347.249 752.045 346.831 752.045 346.16C752.045 345.511 751.616 345.159 750.813 345.159H749.284V347.249ZM754.596 342.068V340.847H755.982V342.068H754.596ZM754.629 348.514V343.091H755.949V348.514H754.629ZM759.72 348.624C758.037 348.624 757.003 347.326 757.003 345.797C757.003 344.257 758.037 342.981 759.72 342.981C761.392 342.981 762.437 344.257 762.437 345.797C762.437 347.326 761.392 348.624 759.72 348.624ZM759.72 347.469C760.721 347.469 761.117 346.677 761.117 345.797C761.117 344.906 760.721 344.136 759.72 344.136C758.719 344.136 758.323 344.906 758.323 345.797C758.323 346.677 758.719 347.469 759.72 347.469ZM766.462 342.981C767.683 342.981 768.376 343.718 768.376 345.016V348.514H767.056V345.346C767.056 344.521 766.737 344.136 766.055 344.136C765.186 344.136 764.823 344.785 764.823 346.347V348.514H763.503V340.847H764.823V343.707C765.186 343.234 765.747 342.981 766.462 342.981ZM773.175 343.091H774.495V348.514H773.175V347.887C772.79 348.404 772.196 348.624 771.558 348.624C770.194 348.624 769.622 347.634 769.622 346.479V343.091H770.942V346.149C770.942 346.523 770.942 347.469 771.943 347.469C773.175 347.469 773.175 346.116 773.175 345.148V343.091ZM778.932 342.981C780.263 342.981 781.22 344.026 781.22 345.797C781.22 347.425 780.406 348.624 778.932 348.624C778.349 348.624 777.744 348.437 777.37 347.975V348.514H776.05V340.847H777.37V343.641C777.711 343.234 778.316 342.981 778.932 342.981ZM778.613 347.403C779.493 347.403 779.9 346.809 779.9 345.808C779.9 344.796 779.482 344.18 778.602 344.18C777.656 344.18 777.249 344.906 777.249 345.808C777.249 346.71 777.656 347.403 778.613 347.403ZM789.859 340.847H791.234V348.514H789.804L786.592 343.212V348.514H785.217V340.847H786.636L789.859 346.127V340.847ZM797.556 345.731C797.556 345.896 797.545 346.061 797.523 346.237H793.805C793.86 346.952 794.3 347.425 795.158 347.425C795.642 347.425 796.082 347.271 796.456 346.842L797.369 347.645C796.775 348.305 796.06 348.624 795.147 348.624C793.277 348.624 792.485 347.282 792.485 345.83C792.485 344.411 793.255 342.981 795.059 342.981C796.742 342.981 797.556 344.224 797.556 345.731ZM793.794 345.192H796.291C796.269 344.499 795.741 344.081 795.048 344.081C794.245 344.081 793.871 344.653 793.794 345.192ZM801.533 344.136H800.18V346.897C800.18 347.326 800.444 347.524 800.873 347.524C801.06 347.524 801.291 347.48 801.533 347.403V348.459C801.203 348.569 800.873 348.624 800.543 348.624C799.63 348.624 798.86 348.151 798.86 346.996V344.136H797.98V343.091H798.86V341.826L800.18 340.847V343.091H801.533V344.136ZM803.647 348.514L801.975 343.091H803.383L804.307 346.49L805.33 343.091H806.463L807.486 346.479L808.421 343.091H809.829L808.157 348.514H806.969L805.902 344.961L804.835 348.514H803.647ZM812.732 348.624C811.049 348.624 810.015 347.326 810.015 345.797C810.015 344.257 811.049 342.981 812.732 342.981C814.404 342.981 815.449 344.257 815.449 345.797C815.449 347.326 814.404 348.624 812.732 348.624ZM812.732 347.469C813.733 347.469 814.129 346.677 814.129 345.797C814.129 344.906 813.733 344.136 812.732 344.136C811.731 344.136 811.335 344.906 811.335 345.797C811.335 346.677 811.731 347.469 812.732 347.469ZM819.287 342.981C819.65 342.981 819.969 343.069 820.321 343.289L819.683 344.455C819.496 344.334 819.287 344.268 819.023 344.268C818.22 344.268 817.824 344.763 817.824 345.786V348.514H816.504V343.091H817.835V344.015C818.066 343.344 818.671 342.981 819.287 342.981ZM821.006 348.514V340.847H822.326V345.291L824.317 343.091H826.088L824.064 345.192L826.319 348.514H824.746L823.162 346.006L822.326 346.93V348.514H821.006Z" fill="black" /> <g class="al-2023-active-dots navy" id="active dots_10"> <circle id="Ellipse 2765_10" cx="727.256" cy="334.861" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_10" cx="727.256" cy="334.861" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_10" cx="727.256" cy="334.861" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive dot_10" cx="727.256" cy="334.861" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_10" cx="727.256" cy="334.861" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="11-Pediatric-and-Ancestry-Networks-for-a-Human-Cell-Atlas" data-milestone="pediatric-and-ancestry-networks-for-a-human-cell-atlas" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_31" d="M240.524 100.95L240.523 334.484" stroke="#22704F" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" d="M240.523 334.484L330.684 334.484C336.206 334.484 340.684 330.007 340.684 324.484V324.05" stroke="url(#paint20_linear_42_3042)" stroke-width="1.5" stroke-linecap="round"/> <path class="al-2023-svg-text" d="M220.637 361.464V353.797H223.145C224.861 353.797 225.752 354.545 225.752 356.008C225.752 357.493 224.839 358.285 223.145 358.285H222.001V361.464H220.637ZM222.001 357.02H223.002C223.97 357.02 224.377 356.723 224.377 356.03C224.377 355.337 223.981 355.062 223.002 355.062H222.001V357.02ZM231.042 358.681C231.042 358.846 231.031 359.011 231.009 359.187H227.291C227.346 359.902 227.786 360.375 228.644 360.375C229.128 360.375 229.568 360.221 229.942 359.792L230.855 360.595C230.261 361.255 229.546 361.574 228.633 361.574C226.763 361.574 225.971 360.232 225.971 358.78C225.971 357.361 226.741 355.931 228.545 355.931C230.228 355.931 231.042 357.174 231.042 358.681ZM227.28 358.142H229.777C229.755 357.449 229.227 357.031 228.534 357.031C227.731 357.031 227.357 357.603 227.28 358.142ZM235.558 353.797H236.878V361.464H235.558V360.925C235.184 361.387 234.579 361.574 233.996 361.574C232.522 361.574 231.708 360.375 231.708 358.747C231.708 356.976 232.665 355.931 233.996 355.931C234.612 355.931 235.217 356.184 235.558 356.591V353.797ZM234.315 360.353C235.272 360.353 235.679 359.66 235.679 358.758C235.679 357.856 235.272 357.13 234.326 357.13C233.446 357.13 233.028 357.746 233.028 358.758C233.028 359.759 233.435 360.353 234.315 360.353ZM238.399 355.018V353.797H239.785V355.018H238.399ZM238.432 361.464V356.041H239.752V361.464H238.432ZM243.39 355.931C244.82 355.931 245.711 356.734 245.711 358.043V361.464H244.501L244.391 360.76C244.072 361.266 243.456 361.574 242.741 361.574C241.597 361.574 240.783 360.837 240.783 359.803C240.783 359.165 241.069 358.681 241.597 358.439C241.96 358.274 242.422 358.197 243.038 358.197H244.391V358.043C244.391 357.449 243.995 357.086 243.368 357.086C242.818 357.086 242.301 357.372 241.905 357.9L240.948 357.097C241.597 356.316 242.4 355.931 243.39 355.931ZM242.95 360.452C243.742 360.452 244.391 359.891 244.391 359.187H243.214C242.763 359.187 242.499 359.242 242.323 359.374C242.18 359.473 242.103 359.627 242.103 359.825C242.103 360.21 242.422 360.452 242.95 360.452ZM249.962 357.086H248.609V359.847C248.609 360.276 248.873 360.474 249.302 360.474C249.489 360.474 249.72 360.43 249.962 360.353V361.409C249.632 361.519 249.302 361.574 248.972 361.574C248.059 361.574 247.289 361.101 247.289 359.946V357.086H246.409V356.041H247.289V354.776L248.609 353.797V356.041H249.962V357.086ZM253.826 355.931C254.189 355.931 254.508 356.019 254.86 356.239L254.222 357.405C254.035 357.284 253.826 357.218 253.562 357.218C252.759 357.218 252.363 357.713 252.363 358.736V361.464H251.043V356.041H252.374V356.965C252.605 356.294 253.21 355.931 253.826 355.931ZM255.5 355.018V353.797H256.886V355.018H255.5ZM255.533 361.464V356.041H256.853V361.464H255.533ZM260.547 361.574C258.776 361.574 257.918 360.199 257.918 358.769C257.918 357.339 258.765 355.931 260.536 355.931C261.614 355.931 262.461 356.448 262.879 357.526L261.625 358.021C261.482 357.449 261.075 357.086 260.536 357.086C259.623 357.086 259.271 357.911 259.271 358.769C259.271 359.627 259.612 360.419 260.536 360.419C261.064 360.419 261.482 360.067 261.625 359.506L262.824 359.968C262.461 360.98 261.625 361.574 260.547 361.574ZM268.602 355.931C270.032 355.931 270.923 356.734 270.923 358.043V361.464H269.713L269.603 360.76C269.284 361.266 268.668 361.574 267.953 361.574C266.809 361.574 265.995 360.837 265.995 359.803C265.995 359.165 266.281 358.681 266.809 358.439C267.172 358.274 267.634 358.197 268.25 358.197H269.603V358.043C269.603 357.449 269.207 357.086 268.58 357.086C268.03 357.086 267.513 357.372 267.117 357.9L266.16 357.097C266.809 356.316 267.612 355.931 268.602 355.931ZM268.162 360.452C268.954 360.452 269.603 359.891 269.603 359.187H268.426C267.975 359.187 267.711 359.242 267.535 359.374C267.392 359.473 267.315 359.627 267.315 359.825C267.315 360.21 267.634 360.452 268.162 360.452ZM275.272 355.931C276.493 355.931 277.186 356.679 277.186 357.966V361.464H275.866V358.296C275.866 357.922 275.866 357.086 274.865 357.086C273.633 357.086 273.633 358.329 273.633 359.297V361.464H272.313V356.041H273.633V356.668C274.018 356.151 274.612 355.931 275.272 355.931ZM282.04 353.797H283.36V361.464H282.04V360.925C281.666 361.387 281.061 361.574 280.478 361.574C279.004 361.574 278.19 360.375 278.19 358.747C278.19 356.976 279.147 355.931 280.478 355.931C281.094 355.931 281.699 356.184 282.04 356.591V353.797ZM280.797 360.353C281.754 360.353 282.161 359.66 282.161 358.758C282.161 357.856 281.754 357.13 280.808 357.13C279.928 357.13 279.51 357.746 279.51 358.758C279.51 359.759 279.917 360.353 280.797 360.353ZM292.527 361.464L291.944 359.88H288.941L288.358 361.464H286.862L289.931 353.797H290.965L294.023 361.464H292.527ZM289.414 358.615H291.482L290.448 355.821L289.414 358.615ZM297.777 355.931C298.998 355.931 299.691 356.679 299.691 357.966V361.464H298.371V358.296C298.371 357.922 298.371 357.086 297.37 357.086C296.138 357.086 296.138 358.329 296.138 359.297V361.464H294.818V356.041H296.138V356.668C296.523 356.151 297.117 355.931 297.777 355.931ZM303.269 361.574C301.498 361.574 300.64 360.199 300.64 358.769C300.64 357.339 301.487 355.931 303.258 355.931C304.336 355.931 305.183 356.448 305.601 357.526L304.347 358.021C304.204 357.449 303.797 357.086 303.258 357.086C302.345 357.086 301.993 357.911 301.993 358.769C301.993 359.627 302.334 360.419 303.258 360.419C303.786 360.419 304.204 360.067 304.347 359.506L305.546 359.968C305.183 360.98 304.347 361.574 303.269 361.574ZM311.114 358.681C311.114 358.846 311.103 359.011 311.081 359.187H307.363C307.418 359.902 307.858 360.375 308.716 360.375C309.2 360.375 309.64 360.221 310.014 359.792L310.927 360.595C310.333 361.255 309.618 361.574 308.705 361.574C306.835 361.574 306.043 360.232 306.043 358.78C306.043 357.361 306.813 355.931 308.617 355.931C310.3 355.931 311.114 357.174 311.114 358.681ZM307.352 358.142H309.849C309.827 357.449 309.299 357.031 308.606 357.031C307.803 357.031 307.429 357.603 307.352 358.142ZM313.903 361.574C312.759 361.574 311.89 360.881 311.626 360.056L312.682 359.583C312.825 359.979 313.111 360.474 313.837 360.474C314.453 360.474 314.717 360.122 314.717 359.836C314.717 358.923 311.923 359.528 311.923 357.515C311.923 356.47 312.869 355.931 313.914 355.931C314.849 355.931 315.564 356.371 315.971 357.108L314.948 357.669C314.761 357.328 314.464 356.976 313.87 356.976C313.441 356.976 313.177 357.185 313.177 357.438C313.177 358.263 316.015 357.779 316.015 359.759C316.015 361.024 314.926 361.574 313.903 361.574ZM320.022 357.086H318.669V359.847C318.669 360.276 318.933 360.474 319.362 360.474C319.549 360.474 319.78 360.43 320.022 360.353V361.409C319.692 361.519 319.362 361.574 319.032 361.574C318.119 361.574 317.349 361.101 317.349 359.946V357.086H316.469V356.041H317.349V354.776L318.669 353.797V356.041H320.022V357.086ZM323.887 355.931C324.25 355.931 324.569 356.019 324.921 356.239L324.283 357.405C324.096 357.284 323.887 357.218 323.623 357.218C322.82 357.218 322.424 357.713 322.424 358.736V361.464H321.104V356.041H322.435V356.965C322.666 356.294 323.271 355.931 323.887 355.931ZM326.16 363.708L327.128 361.321L325.005 356.041H326.457L327.832 359.803L329.218 356.041H330.67L327.59 363.708H326.16ZM225.279 365.797H226.654V373.464H225.224L222.012 368.162V373.464H220.637V365.797H222.056L225.279 371.077V365.797ZM232.976 370.681C232.976 370.846 232.965 371.011 232.943 371.187H229.225C229.28 371.902 229.72 372.375 230.578 372.375C231.062 372.375 231.502 372.221 231.876 371.792L232.789 372.595C232.195 373.255 231.48 373.574 230.567 373.574C228.697 373.574 227.905 372.232 227.905 370.78C227.905 369.361 228.675 367.931 230.479 367.931C232.162 367.931 232.976 369.174 232.976 370.681ZM229.214 370.142H231.711C231.689 369.449 231.161 369.031 230.468 369.031C229.665 369.031 229.291 369.603 229.214 370.142ZM236.953 369.086H235.6V371.847C235.6 372.276 235.864 372.474 236.293 372.474C236.48 372.474 236.711 372.43 236.953 372.353V373.409C236.623 373.519 236.293 373.574 235.963 373.574C235.05 373.574 234.28 373.101 234.28 371.946V369.086H233.4V368.041H234.28V366.776L235.6 365.797V368.041H236.953V369.086ZM239.066 373.464L237.394 368.041H238.802L239.726 371.44L240.749 368.041H241.882L242.905 371.429L243.84 368.041H245.248L243.576 373.464H242.388L241.321 369.911L240.254 373.464H239.066ZM248.152 373.574C246.469 373.574 245.435 372.276 245.435 370.747C245.435 369.207 246.469 367.931 248.152 367.931C249.824 367.931 250.869 369.207 250.869 370.747C250.869 372.276 249.824 373.574 248.152 373.574ZM248.152 372.419C249.153 372.419 249.549 371.627 249.549 370.747C249.549 369.856 249.153 369.086 248.152 369.086C247.151 369.086 246.755 369.856 246.755 370.747C246.755 371.627 247.151 372.419 248.152 372.419ZM254.707 367.931C255.07 367.931 255.389 368.019 255.741 368.239L255.103 369.405C254.916 369.284 254.707 369.218 254.443 369.218C253.64 369.218 253.244 369.713 253.244 370.736V373.464H251.924V368.041H253.255V368.965C253.486 368.294 254.091 367.931 254.707 367.931ZM256.425 373.464V365.797H257.745V370.241L259.736 368.041H261.507L259.483 370.142L261.738 373.464H260.165L258.581 370.956L257.745 371.88V373.464H256.425ZM264.146 373.574C263.002 373.574 262.133 372.881 261.869 372.056L262.925 371.583C263.068 371.979 263.354 372.474 264.08 372.474C264.696 372.474 264.96 372.122 264.96 371.836C264.96 370.923 262.166 371.528 262.166 369.515C262.166 368.47 263.112 367.931 264.157 367.931C265.092 367.931 265.807 368.371 266.214 369.108L265.191 369.669C265.004 369.328 264.707 368.976 264.113 368.976C263.684 368.976 263.42 369.185 263.42 369.438C263.42 370.263 266.258 369.779 266.258 371.759C266.258 373.024 265.169 373.574 264.146 373.574ZM270.365 373.464V369.086H269.331V368.041H270.376V367.425C270.376 366.05 271.157 365.687 272.015 365.687C272.433 365.687 272.752 365.775 273.038 365.907L272.609 366.919C272.488 366.842 272.334 366.787 272.158 366.787C271.685 366.787 271.685 367.216 271.685 367.414V368.041H272.95V369.086H271.685V373.464H270.365ZM275.803 373.574C274.12 373.574 273.086 372.276 273.086 370.747C273.086 369.207 274.12 367.931 275.803 367.931C277.475 367.931 278.52 369.207 278.52 370.747C278.52 372.276 277.475 373.574 275.803 373.574ZM275.803 372.419C276.804 372.419 277.2 371.627 277.2 370.747C277.2 369.856 276.804 369.086 275.803 369.086C274.802 369.086 274.406 369.856 274.406 370.747C274.406 371.627 274.802 372.419 275.803 372.419ZM282.357 367.931C282.72 367.931 283.039 368.019 283.391 368.239L282.753 369.405C282.566 369.284 282.357 369.218 282.093 369.218C281.29 369.218 280.894 369.713 280.894 370.736V373.464H279.574V368.041H280.905V368.965C281.136 368.294 281.741 367.931 282.357 367.931ZM288.808 367.931C290.238 367.931 291.129 368.734 291.129 370.043V373.464H289.919L289.809 372.76C289.49 373.266 288.874 373.574 288.159 373.574C287.015 373.574 286.201 372.837 286.201 371.803C286.201 371.165 286.487 370.681 287.015 370.439C287.378 370.274 287.84 370.197 288.456 370.197H289.809V370.043C289.809 369.449 289.413 369.086 288.786 369.086C288.236 369.086 287.719 369.372 287.323 369.9L286.366 369.097C287.015 368.316 287.818 367.931 288.808 367.931ZM288.368 372.452C289.16 372.452 289.809 371.891 289.809 371.187H288.632C288.181 371.187 287.917 371.242 287.741 371.374C287.598 371.473 287.521 371.627 287.521 371.825C287.521 372.21 287.84 372.452 288.368 372.452ZM295.392 373.464V365.797H296.767V368.888H300.122V365.797H301.497V373.464H300.122V370.153H296.767V373.464H295.392ZM306.66 368.041H307.98V373.464H306.66V372.837C306.275 373.354 305.681 373.574 305.043 373.574C303.679 373.574 303.107 372.584 303.107 371.429V368.041H304.427V371.099C304.427 371.473 304.427 372.419 305.428 372.419C306.66 372.419 306.66 371.066 306.66 370.098V368.041ZM315.585 367.931C316.894 367.931 317.477 368.921 317.477 370.01V373.464H316.157V370.406C316.157 369.977 316.102 369.086 315.233 369.086C314.122 369.086 314.166 370.307 314.166 371.396V373.464H312.846V370.406C312.846 369.977 312.791 369.086 311.933 369.086C310.822 369.086 310.855 370.307 310.855 371.396V373.464H309.535L309.524 368.041H310.8V368.723C311.152 368.118 311.713 367.931 312.252 367.931C312.846 367.931 313.506 368.162 313.836 368.998C314.254 368.184 314.881 367.931 315.585 367.931ZM320.981 367.931C322.411 367.931 323.302 368.734 323.302 370.043V373.464H322.092L321.982 372.76C321.663 373.266 321.047 373.574 320.332 373.574C319.188 373.574 318.374 372.837 318.374 371.803C318.374 371.165 318.66 370.681 319.188 370.439C319.551 370.274 320.013 370.197 320.629 370.197H321.982V370.043C321.982 369.449 321.586 369.086 320.959 369.086C320.409 369.086 319.892 369.372 319.496 369.9L318.539 369.097C319.188 368.316 319.991 367.931 320.981 367.931ZM320.541 372.452C321.333 372.452 321.982 371.891 321.982 371.187H320.805C320.354 371.187 320.09 371.242 319.914 371.374C319.771 371.473 319.694 371.627 319.694 371.825C319.694 372.21 320.013 372.452 320.541 372.452ZM327.651 367.931C328.872 367.931 329.565 368.679 329.565 369.966V373.464H328.245V370.296C328.245 369.922 328.245 369.086 327.244 369.086C326.012 369.086 326.012 370.329 326.012 371.297V373.464H324.692V368.041H326.012V368.668C326.397 368.151 326.991 367.931 327.651 367.931ZM223.805 385.629C221.539 385.629 220.087 384.078 220.087 381.625C220.087 379.172 221.539 377.621 223.805 377.621C225.422 377.621 226.643 378.402 227.204 379.865L225.939 380.36C225.598 379.403 224.85 378.93 223.805 378.93C222.32 378.93 221.462 379.898 221.462 381.614C221.462 383.341 222.331 384.32 223.805 384.32C224.861 384.32 225.609 383.825 225.939 382.857L227.226 383.341C226.676 384.826 225.444 385.629 223.805 385.629ZM232.675 382.681C232.675 382.846 232.664 383.011 232.642 383.187H228.924C228.979 383.902 229.419 384.375 230.277 384.375C230.761 384.375 231.201 384.221 231.575 383.792L232.488 384.595C231.894 385.255 231.179 385.574 230.266 385.574C228.396 385.574 227.604 384.232 227.604 382.78C227.604 381.361 228.374 379.931 230.178 379.931C231.861 379.931 232.675 381.174 232.675 382.681ZM228.913 382.142H231.41C231.388 381.449 230.86 381.031 230.167 381.031C229.364 381.031 228.99 381.603 228.913 382.142ZM234.98 385.574C234.243 385.574 233.704 385.134 233.704 384.166V377.797H235.024V384.078C235.024 384.32 235.167 384.419 235.409 384.419C235.53 384.419 235.673 384.397 235.827 384.353V385.409C235.53 385.519 235.233 385.574 234.98 385.574ZM238.042 385.574C237.305 385.574 236.766 385.134 236.766 384.166V377.797H238.086V384.078C238.086 384.32 238.229 384.419 238.471 384.419C238.592 384.419 238.735 384.397 238.889 384.353V385.409C238.592 385.519 238.295 385.574 238.042 385.574ZM247.496 385.464L246.913 383.88H243.91L243.327 385.464H241.831L244.9 377.797H245.934L248.992 385.464H247.496ZM244.383 382.615H246.451L245.417 379.821L244.383 382.615ZM252.454 381.086H251.101V383.847C251.101 384.276 251.365 384.474 251.794 384.474C251.981 384.474 252.212 384.43 252.454 384.353V385.409C252.124 385.519 251.794 385.574 251.464 385.574C250.551 385.574 249.781 385.101 249.781 383.946V381.086H248.901V380.041H249.781V378.776L251.101 377.797V380.041H252.454V381.086ZM254.563 385.574C253.826 385.574 253.287 385.134 253.287 384.166V377.797H254.607V384.078C254.607 384.32 254.75 384.419 254.992 384.419C255.113 384.419 255.256 384.397 255.41 384.353V385.409C255.113 385.519 254.816 385.574 254.563 385.574ZM258.472 379.931C259.902 379.931 260.793 380.734 260.793 382.043V385.464H259.583L259.473 384.76C259.154 385.266 258.538 385.574 257.823 385.574C256.679 385.574 255.865 384.837 255.865 383.803C255.865 383.165 256.151 382.681 256.679 382.439C257.042 382.274 257.504 382.197 258.12 382.197H259.473V382.043C259.473 381.449 259.077 381.086 258.45 381.086C257.9 381.086 257.383 381.372 256.987 381.9L256.03 381.097C256.679 380.316 257.482 379.931 258.472 379.931ZM258.032 384.452C258.824 384.452 259.473 383.891 259.473 383.187H258.296C257.845 383.187 257.581 383.242 257.405 383.374C257.262 383.473 257.185 383.627 257.185 383.825C257.185 384.21 257.504 384.452 258.032 384.452ZM263.888 385.574C262.744 385.574 261.875 384.881 261.611 384.056L262.667 383.583C262.81 383.979 263.096 384.474 263.822 384.474C264.438 384.474 264.702 384.122 264.702 383.836C264.702 382.923 261.908 383.528 261.908 381.515C261.908 380.47 262.854 379.931 263.899 379.931C264.834 379.931 265.549 380.371 265.956 381.108L264.933 381.669C264.746 381.328 264.449 380.976 263.855 380.976C263.426 380.976 263.162 381.185 263.162 381.438C263.162 382.263 266 381.779 266 383.759C266 385.024 264.911 385.574 263.888 385.574Z" fill="black" /> <g class="al-2023-active-dots green" id="active dots_11"> <circle id="Ellipse 2765_11" cx="242.225" cy="333.508" r="48.5676" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2767_11" cx="242.225" cy="333.508" r="25.309" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2771_11" cx="242.225" cy="333.508" r="13.0446" fill="white" stroke="#22704F" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot green" id="inactive dot_11" cx="242.225" cy="333.508" r="10.2374" fill="#22704F" stroke="white" stroke-width="3" /> <circle class="overlay-dot green" id="inactive dot_11" cx="242.225" cy="333.508" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="10-Single-Cell-Biology-Data-Insights" data-milestone="single-cell-biology-data-insights" class="al-2023-svg-milestone"> <g id="connector-line_32"> <path class="al-2023-connector-line" d="M193.598 334.336V466.074C193.598 475.463 201.209 483.074 210.598 483.074H328.215C335.101 483.074 340.684 477.492 340.684 470.605V470.605" stroke="black" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" d="M193.598 334.336V466.074C193.598 475.463 201.209 483.074 210.598 483.074H328.215C335.101 483.074 340.684 477.492 340.684 470.605V470.605" stroke="url(#paint12_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> </g> <path class="al-2023-connector-line" id="connector-line_33" d="M240.523 100.95L195.877 335.171" stroke="#22704F" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M171.482 284.903C170.976 284.903 170.514 284.808 170.096 284.617C169.678 284.427 169.334 284.159 169.062 283.814C168.791 283.462 168.619 283.055 168.545 282.593L169.909 282.252C169.961 282.707 170.126 283.059 170.404 283.308C170.69 283.558 171.057 283.682 171.504 283.682C171.893 283.682 172.201 283.591 172.428 283.407C172.656 283.224 172.769 282.971 172.769 282.648C172.769 282.384 172.656 282.157 172.428 281.966C172.208 281.776 171.812 281.567 171.24 281.339C170.698 281.127 170.269 280.914 169.953 280.701C169.638 280.489 169.411 280.25 169.271 279.986C169.132 279.715 169.062 279.392 169.062 279.018C169.062 278.608 169.161 278.245 169.359 277.929C169.557 277.614 169.836 277.368 170.195 277.192C170.562 277.016 170.98 276.928 171.449 276.928C171.97 276.928 172.428 277.046 172.824 277.28C173.22 277.515 173.539 277.863 173.781 278.325L172.637 279.029C172.505 278.743 172.333 278.527 172.12 278.38C171.908 278.226 171.669 278.149 171.405 278.149C171.134 278.149 170.903 278.23 170.712 278.391C170.529 278.553 170.437 278.751 170.437 278.985C170.437 279.235 170.547 279.447 170.767 279.623C170.987 279.799 171.383 280.001 171.955 280.228C172.513 280.441 172.949 280.654 173.264 280.866C173.58 281.079 173.803 281.317 173.935 281.581C174.075 281.838 174.144 282.153 174.144 282.527C174.144 282.997 174.031 283.411 173.803 283.77C173.583 284.13 173.272 284.408 172.868 284.606C172.465 284.804 172.003 284.903 171.482 284.903ZM175.186 279.337H176.506V284.76H175.186V279.337ZM175.153 277.093H176.539V278.314H175.153V277.093ZM181.002 279.227C181.611 279.227 182.08 279.407 182.41 279.766C182.748 280.118 182.916 280.617 182.916 281.262V284.76H181.596V281.592C181.596 281.262 181.538 280.98 181.42 280.745C181.303 280.503 181.028 280.382 180.595 280.382C180.214 280.382 179.932 280.492 179.748 280.712C179.572 280.925 179.462 281.182 179.418 281.482C179.382 281.776 179.363 282.146 179.363 282.593V284.76H178.043V279.337H179.363V279.964C179.547 279.715 179.778 279.532 180.056 279.414C180.342 279.29 180.658 279.227 181.002 279.227ZM186.417 283.935C186.975 284.009 187.411 284.082 187.726 284.155C188.042 284.229 188.32 284.372 188.562 284.584C188.812 284.797 188.936 285.101 188.936 285.497C188.936 286.04 188.713 286.443 188.265 286.707C187.818 286.979 187.209 287.114 186.439 287.114C185.625 287.114 184.998 286.968 184.558 286.674C184.118 286.381 183.898 285.956 183.898 285.398C183.898 285.31 183.906 285.23 183.92 285.156L184.701 284.661C184.269 284.427 184.052 284.056 184.052 283.55C184.052 283.118 184.221 282.755 184.558 282.461C184.265 282.095 184.118 281.68 184.118 281.218C184.118 280.837 184.217 280.496 184.415 280.195C184.621 279.887 184.892 279.649 185.229 279.48C185.567 279.312 185.937 279.227 186.34 279.227C186.817 279.227 187.242 279.341 187.616 279.568L188.441 278.864L189.134 279.7L188.353 280.338C188.507 280.632 188.584 280.947 188.584 281.284C188.584 281.673 188.485 282.018 188.287 282.318C188.089 282.619 187.822 282.854 187.484 283.022C187.147 283.184 186.78 283.264 186.384 283.264C186.025 283.264 185.677 283.195 185.339 283.055C185.237 283.121 185.185 283.217 185.185 283.341C185.185 283.525 185.288 283.657 185.493 283.737C185.699 283.818 186.007 283.884 186.417 283.935ZM186.362 280.327C186.084 280.327 185.86 280.412 185.691 280.58C185.523 280.749 185.438 280.973 185.438 281.251C185.438 281.523 185.519 281.746 185.68 281.922C185.842 282.098 186.069 282.186 186.362 282.186C186.656 282.186 186.879 282.102 187.033 281.933C187.187 281.757 187.264 281.53 187.264 281.251C187.264 280.973 187.184 280.749 187.022 280.58C186.861 280.412 186.641 280.327 186.362 280.327ZM186.494 286.124C186.81 286.124 187.074 286.084 187.286 286.003C187.506 285.923 187.616 285.794 187.616 285.618C187.616 285.45 187.517 285.332 187.319 285.266C187.121 285.2 186.81 285.138 186.384 285.079L186.142 285.046L185.691 284.98L185.218 285.431C185.211 285.453 185.207 285.483 185.207 285.519C185.207 285.732 185.332 285.886 185.581 285.981C185.831 286.077 186.135 286.124 186.494 286.124ZM191.21 284.87C190.821 284.87 190.509 284.753 190.275 284.518C190.047 284.284 189.934 283.932 189.934 283.462V277.093H191.254V283.374C191.254 283.602 191.382 283.715 191.639 283.715C191.763 283.715 191.903 283.693 192.057 283.649V284.705C191.763 284.815 191.481 284.87 191.21 284.87ZM197.67 281.977C197.67 282.139 197.659 282.307 197.637 282.483H193.919C193.948 282.85 194.077 283.14 194.304 283.352C194.531 283.565 194.854 283.671 195.272 283.671C195.8 283.671 196.233 283.477 196.57 283.088L197.483 283.891C197.182 284.221 196.849 284.467 196.482 284.628C196.123 284.79 195.716 284.87 195.261 284.87C194.667 284.87 194.168 284.742 193.765 284.485C193.369 284.229 193.076 283.891 192.885 283.473C192.694 283.048 192.599 282.582 192.599 282.076C192.599 281.578 192.691 281.112 192.874 280.679C193.065 280.247 193.351 279.898 193.732 279.634C194.121 279.363 194.601 279.227 195.173 279.227C195.716 279.227 196.174 279.348 196.548 279.59C196.922 279.832 197.201 280.162 197.384 280.58C197.575 280.998 197.67 281.464 197.67 281.977ZM196.405 281.438C196.398 281.101 196.277 280.833 196.042 280.635C195.807 280.43 195.514 280.327 195.162 280.327C194.788 280.327 194.495 280.437 194.282 280.657C194.077 280.87 193.952 281.13 193.908 281.438H196.405ZM198.732 281.009H201.9V281.999H198.732V281.009ZM206.782 284.925C206.034 284.925 205.378 284.764 204.813 284.441C204.256 284.111 203.823 283.646 203.515 283.044C203.215 282.436 203.064 281.728 203.064 280.921C203.064 280.115 203.215 279.411 203.515 278.809C203.823 278.201 204.256 277.735 204.813 277.412C205.378 277.082 206.034 276.917 206.782 276.917C207.596 276.917 208.297 277.112 208.883 277.5C209.47 277.882 209.903 278.435 210.181 279.161L208.916 279.656C208.748 279.18 208.48 278.824 208.113 278.589C207.754 278.347 207.31 278.226 206.782 278.226C206.042 278.226 205.466 278.461 205.055 278.93C204.645 279.392 204.439 280.052 204.439 280.91C204.439 281.768 204.645 282.436 205.055 282.912C205.466 283.382 206.042 283.616 206.782 283.616C207.31 283.616 207.758 283.495 208.124 283.253C208.491 283.004 208.755 282.637 208.916 282.153L210.203 282.637C209.932 283.378 209.499 283.946 208.905 284.342C208.311 284.731 207.604 284.925 206.782 284.925ZM215.653 281.977C215.653 282.139 215.642 282.307 215.62 282.483H211.902C211.931 282.85 212.059 283.14 212.287 283.352C212.514 283.565 212.837 283.671 213.255 283.671C213.783 283.671 214.215 283.477 214.553 283.088L215.466 283.891C215.165 284.221 214.831 284.467 214.465 284.628C214.105 284.79 213.698 284.87 213.244 284.87C212.65 284.87 212.151 284.742 211.748 284.485C211.352 284.229 211.058 283.891 210.868 283.473C210.677 283.048 210.582 282.582 210.582 282.076C210.582 281.578 210.673 281.112 210.857 280.679C211.047 280.247 211.333 279.898 211.715 279.634C212.103 279.363 212.584 279.227 213.156 279.227C213.698 279.227 214.157 279.348 214.531 279.59C214.905 279.832 215.183 280.162 215.367 280.58C215.557 280.998 215.653 281.464 215.653 281.977ZM214.388 281.438C214.38 281.101 214.259 280.833 214.025 280.635C213.79 280.43 213.497 280.327 213.145 280.327C212.771 280.327 212.477 280.437 212.265 280.657C212.059 280.87 211.935 281.13 211.891 281.438H214.388ZM217.958 284.87C217.569 284.87 217.257 284.753 217.023 284.518C216.795 284.284 216.682 283.932 216.682 283.462V277.093H218.002V283.374C218.002 283.602 218.13 283.715 218.387 283.715C218.511 283.715 218.651 283.693 218.805 283.649V284.705C218.511 284.815 218.229 284.87 217.958 284.87ZM221.019 284.87C220.63 284.87 220.319 284.753 220.084 284.518C219.857 284.284 219.743 283.932 219.743 283.462V277.093H221.063V283.374C221.063 283.602 221.191 283.715 221.448 283.715C221.573 283.715 221.712 283.693 221.866 283.649V284.705C221.573 284.815 221.29 284.87 221.019 284.87ZM165.195 289.093H167.868C168.631 289.093 169.225 289.266 169.65 289.61C170.083 289.948 170.299 290.421 170.299 291.029C170.299 291.389 170.226 291.708 170.079 291.986C169.932 292.258 169.723 292.47 169.452 292.624C170.288 292.925 170.706 293.556 170.706 294.516C170.706 295.22 170.486 295.77 170.046 296.166C169.606 296.562 168.994 296.76 168.209 296.76H165.195V289.093ZM167.868 292.14C168.213 292.14 168.473 292.067 168.649 291.92C168.832 291.774 168.924 291.557 168.924 291.271C168.924 290.978 168.832 290.754 168.649 290.6C168.466 290.439 168.205 290.358 167.868 290.358H166.57V292.14H167.868ZM168.099 295.495C168.48 295.495 168.781 295.4 169.001 295.209C169.221 295.011 169.331 294.744 169.331 294.406C169.331 294.084 169.225 293.838 169.012 293.669C168.807 293.493 168.502 293.405 168.099 293.405H166.57V295.495H168.099ZM171.915 291.337H173.235V296.76H171.915V291.337ZM171.882 289.093H173.268V290.314H171.882V289.093ZM177.005 296.87C176.463 296.87 175.982 296.746 175.564 296.496C175.154 296.24 174.838 295.895 174.618 295.462C174.398 295.03 174.288 294.557 174.288 294.043C174.288 293.53 174.398 293.061 174.618 292.635C174.838 292.203 175.154 291.862 175.564 291.612C175.982 291.356 176.463 291.227 177.005 291.227C177.548 291.227 178.025 291.356 178.435 291.612C178.846 291.862 179.161 292.203 179.381 292.635C179.609 293.061 179.722 293.53 179.722 294.043C179.722 294.557 179.609 295.03 179.381 295.462C179.161 295.895 178.846 296.24 178.435 296.496C178.025 296.746 177.548 296.87 177.005 296.87ZM177.005 295.715C177.475 295.715 177.823 295.558 178.05 295.242C178.285 294.927 178.402 294.527 178.402 294.043C178.402 293.559 178.285 293.163 178.05 292.855C177.823 292.54 177.475 292.382 177.005 292.382C176.536 292.382 176.184 292.54 175.949 292.855C175.722 293.163 175.608 293.559 175.608 294.043C175.608 294.527 175.722 294.927 175.949 295.242C176.184 295.558 176.536 295.715 177.005 295.715ZM181.998 296.87C181.609 296.87 181.298 296.753 181.063 296.518C180.836 296.284 180.722 295.932 180.722 295.462V289.093H182.042V295.374C182.042 295.602 182.17 295.715 182.427 295.715C182.552 295.715 182.691 295.693 182.845 295.649V296.705C182.552 296.815 182.269 296.87 181.998 296.87ZM186.072 296.87C185.529 296.87 185.049 296.746 184.631 296.496C184.22 296.24 183.905 295.895 183.685 295.462C183.465 295.03 183.355 294.557 183.355 294.043C183.355 293.53 183.465 293.061 183.685 292.635C183.905 292.203 184.22 291.862 184.631 291.612C185.049 291.356 185.529 291.227 186.072 291.227C186.614 291.227 187.091 291.356 187.502 291.612C187.912 291.862 188.228 292.203 188.448 292.635C188.675 293.061 188.789 293.53 188.789 294.043C188.789 294.557 188.675 295.03 188.448 295.462C188.228 295.895 187.912 296.24 187.502 296.496C187.091 296.746 186.614 296.87 186.072 296.87ZM186.072 295.715C186.541 295.715 186.889 295.558 187.117 295.242C187.351 294.927 187.469 294.527 187.469 294.043C187.469 293.559 187.351 293.163 187.117 292.855C186.889 292.54 186.541 292.382 186.072 292.382C185.602 292.382 185.25 292.54 185.016 292.855C184.788 293.163 184.675 293.559 184.675 294.043C184.675 294.527 184.788 294.927 185.016 295.242C185.25 295.558 185.602 295.715 186.072 295.715ZM191.923 295.935C192.48 296.009 192.916 296.082 193.232 296.155C193.547 296.229 193.826 296.372 194.068 296.584C194.317 296.797 194.442 297.101 194.442 297.497C194.442 298.04 194.218 298.443 193.771 298.707C193.323 298.979 192.715 299.114 191.945 299.114C191.131 299.114 190.504 298.968 190.064 298.674C189.624 298.381 189.404 297.956 189.404 297.398C189.404 297.31 189.411 297.23 189.426 297.156L190.207 296.661C189.774 296.427 189.558 296.056 189.558 295.55C189.558 295.118 189.726 294.755 190.064 294.461C189.77 294.095 189.624 293.68 189.624 293.218C189.624 292.837 189.723 292.496 189.921 292.195C190.126 291.887 190.397 291.649 190.735 291.48C191.072 291.312 191.442 291.227 191.846 291.227C192.322 291.227 192.748 291.341 193.122 291.568L193.947 290.864L194.64 291.7L193.859 292.338C194.013 292.632 194.09 292.947 194.09 293.284C194.09 293.673 193.991 294.018 193.793 294.318C193.595 294.619 193.327 294.854 192.99 295.022C192.652 295.184 192.286 295.264 191.89 295.264C191.53 295.264 191.182 295.195 190.845 295.055C190.742 295.121 190.691 295.217 190.691 295.341C190.691 295.525 190.793 295.657 190.999 295.737C191.204 295.818 191.512 295.884 191.923 295.935ZM191.868 292.327C191.589 292.327 191.365 292.412 191.197 292.58C191.028 292.749 190.944 292.973 190.944 293.251C190.944 293.523 191.024 293.746 191.186 293.922C191.347 294.098 191.574 294.186 191.868 294.186C192.161 294.186 192.385 294.102 192.539 293.933C192.693 293.757 192.77 293.53 192.77 293.251C192.77 292.973 192.689 292.749 192.528 292.58C192.366 292.412 192.146 292.327 191.868 292.327ZM192 298.124C192.315 298.124 192.579 298.084 192.792 298.003C193.012 297.923 193.122 297.794 193.122 297.618C193.122 297.45 193.023 297.332 192.825 297.266C192.627 297.2 192.315 297.138 191.89 297.079L191.648 297.046L191.197 296.98L190.724 297.431C190.716 297.453 190.713 297.483 190.713 297.519C190.713 297.732 190.837 297.886 191.087 297.981C191.336 298.077 191.64 298.124 192 298.124ZM196.738 296.617L194.615 291.337H196.067L197.442 295.099L198.828 291.337H200.28L197.2 299.004H195.77L196.738 296.617ZM203.867 289.093H206.089C207.357 289.093 208.34 289.434 209.037 290.116C209.733 290.791 210.082 291.748 210.082 292.987C210.082 294.212 209.737 295.147 209.048 295.792C208.366 296.438 207.376 296.76 206.078 296.76H203.867V289.093ZM205.946 295.495C206.914 295.495 207.614 295.294 208.047 294.89C208.479 294.487 208.696 293.834 208.696 292.932C208.696 292.045 208.483 291.396 208.058 290.985C207.64 290.567 206.976 290.358 206.067 290.358H205.242V295.495H205.946ZM213.375 291.227C214.094 291.227 214.659 291.418 215.069 291.799C215.487 292.173 215.696 292.687 215.696 293.339V296.76H214.486L214.376 296.056C214.215 296.313 213.988 296.515 213.694 296.661C213.408 296.801 213.086 296.87 212.726 296.87C212.352 296.87 212.015 296.797 211.714 296.65C211.421 296.496 211.19 296.284 211.021 296.012C210.853 295.741 210.768 295.437 210.768 295.099C210.768 294.777 210.838 294.498 210.977 294.263C211.117 294.029 211.318 293.853 211.582 293.735C211.934 293.574 212.415 293.493 213.023 293.493H214.376V293.339C214.376 293.046 214.285 292.815 214.101 292.646C213.918 292.47 213.669 292.382 213.353 292.382C213.075 292.382 212.811 292.452 212.561 292.591C212.312 292.731 212.088 292.932 211.89 293.196L210.933 292.393C211.579 291.616 212.393 291.227 213.375 291.227ZM212.935 295.748C213.331 295.748 213.669 295.627 213.947 295.385C214.233 295.136 214.376 294.835 214.376 294.483H213.199C212.774 294.483 212.477 294.546 212.308 294.67C212.162 294.773 212.088 294.923 212.088 295.121C212.088 295.312 212.162 295.466 212.308 295.583C212.462 295.693 212.671 295.748 212.935 295.748ZM218.594 292.382V295.143C218.594 295.356 218.652 295.514 218.77 295.616C218.894 295.719 219.067 295.77 219.287 295.77C219.47 295.77 219.69 295.73 219.947 295.649V296.705C219.617 296.815 219.287 296.87 218.957 296.87C218.465 296.87 218.062 296.738 217.747 296.474C217.431 296.203 217.274 295.792 217.274 295.242V292.382H216.394V291.337H217.274V290.072L218.594 289.093V291.337H219.947V292.382H218.594ZM223.237 291.227C223.955 291.227 224.52 291.418 224.931 291.799C225.349 292.173 225.558 292.687 225.558 293.339V296.76H224.348L224.238 296.056C224.076 296.313 223.849 296.515 223.556 296.661C223.27 296.801 222.947 296.87 222.588 296.87C222.214 296.87 221.876 296.797 221.576 296.65C221.282 296.496 221.051 296.284 220.883 296.012C220.714 295.741 220.63 295.437 220.63 295.099C220.63 294.777 220.699 294.498 220.839 294.263C220.978 294.029 221.18 293.853 221.444 293.735C221.796 293.574 222.276 293.493 222.885 293.493H224.238V293.339C224.238 293.046 224.146 292.815 223.963 292.646C223.779 292.47 223.53 292.382 223.215 292.382C222.936 292.382 222.672 292.452 222.423 292.591C222.173 292.731 221.95 292.932 221.752 293.196L220.795 292.393C221.44 291.616 222.254 291.227 223.237 291.227ZM222.797 295.748C223.193 295.748 223.53 295.627 223.809 295.385C224.095 295.136 224.238 294.835 224.238 294.483H223.061C222.635 294.483 222.338 294.546 222.17 294.67C222.023 294.773 221.95 294.923 221.95 295.121C221.95 295.312 222.023 295.466 222.17 295.583C222.324 295.693 222.533 295.748 222.797 295.748ZM176.947 301.093H178.322V308.76H176.947V301.093ZM183.016 303.227C183.625 303.227 184.094 303.407 184.424 303.766C184.762 304.118 184.93 304.617 184.93 305.262V308.76H183.61V305.592C183.61 305.262 183.552 304.98 183.434 304.745C183.317 304.503 183.042 304.382 182.609 304.382C182.228 304.382 181.946 304.492 181.762 304.712C181.586 304.925 181.476 305.182 181.432 305.482C181.396 305.776 181.377 306.146 181.377 306.593V308.76H180.057V303.337H181.377V303.964C181.561 303.715 181.792 303.532 182.07 303.414C182.356 303.29 182.672 303.227 183.016 303.227ZM188.057 308.87C187.507 308.87 187.023 308.727 186.605 308.441C186.195 308.148 185.92 307.785 185.78 307.352L186.836 306.879C187.049 307.473 187.434 307.77 187.991 307.77C188.277 307.77 188.494 307.704 188.64 307.572C188.794 307.44 188.871 307.294 188.871 307.132C188.871 306.971 188.794 306.85 188.64 306.769C188.486 306.689 188.233 306.597 187.881 306.494C187.515 306.399 187.21 306.3 186.968 306.197C186.726 306.087 186.517 305.922 186.341 305.702C186.165 305.475 186.077 305.178 186.077 304.811C186.077 304.313 186.268 303.924 186.649 303.645C187.038 303.367 187.511 303.227 188.068 303.227C188.53 303.227 188.937 303.33 189.289 303.535C189.641 303.741 189.92 304.03 190.125 304.404L189.102 304.965C188.992 304.76 188.853 304.595 188.684 304.47C188.516 304.338 188.296 304.272 188.024 304.272C187.819 304.272 187.65 304.316 187.518 304.404C187.394 304.492 187.331 304.602 187.331 304.734C187.331 304.881 187.408 304.995 187.562 305.075C187.724 305.156 187.969 305.24 188.299 305.328C188.681 305.438 188.996 305.548 189.245 305.658C189.495 305.768 189.711 305.937 189.894 306.164C190.078 306.392 190.169 306.689 190.169 307.055C190.169 307.459 190.067 307.796 189.861 308.067C189.663 308.339 189.403 308.54 189.08 308.672C188.758 308.804 188.417 308.87 188.057 308.87ZM191.283 303.337H192.603V308.76H191.283V303.337ZM191.25 301.093H192.636V302.314H191.25V301.093ZM196.219 307.935C196.777 308.009 197.213 308.082 197.528 308.155C197.844 308.229 198.122 308.372 198.364 308.584C198.614 308.797 198.738 309.101 198.738 309.497C198.738 310.04 198.515 310.443 198.067 310.707C197.62 310.979 197.011 311.114 196.241 311.114C195.427 311.114 194.8 310.968 194.36 310.674C193.92 310.381 193.7 309.956 193.7 309.398C193.7 309.31 193.708 309.23 193.722 309.156L194.503 308.661C194.071 308.427 193.854 308.056 193.854 307.55C193.854 307.118 194.023 306.755 194.36 306.461C194.067 306.095 193.92 305.68 193.92 305.218C193.92 304.837 194.019 304.496 194.217 304.195C194.423 303.887 194.694 303.649 195.031 303.48C195.369 303.312 195.739 303.227 196.142 303.227C196.619 303.227 197.044 303.341 197.418 303.568L198.243 302.864L198.936 303.7L198.155 304.338C198.309 304.632 198.386 304.947 198.386 305.284C198.386 305.673 198.287 306.018 198.089 306.318C197.891 306.619 197.624 306.854 197.286 307.022C196.949 307.184 196.582 307.264 196.186 307.264C195.827 307.264 195.479 307.195 195.141 307.055C195.039 307.121 194.987 307.217 194.987 307.341C194.987 307.525 195.09 307.657 195.295 307.737C195.501 307.818 195.809 307.884 196.219 307.935ZM196.164 304.327C195.886 304.327 195.662 304.412 195.493 304.58C195.325 304.749 195.24 304.973 195.24 305.251C195.24 305.523 195.321 305.746 195.482 305.922C195.644 306.098 195.871 306.186 196.164 306.186C196.458 306.186 196.681 306.102 196.835 305.933C196.989 305.757 197.066 305.53 197.066 305.251C197.066 304.973 196.986 304.749 196.824 304.58C196.663 304.412 196.443 304.327 196.164 304.327ZM196.296 310.124C196.612 310.124 196.876 310.084 197.088 310.003C197.308 309.923 197.418 309.794 197.418 309.618C197.418 309.45 197.319 309.332 197.121 309.266C196.923 309.2 196.612 309.138 196.186 309.079L195.944 309.046L195.493 308.98L195.02 309.431C195.013 309.453 195.009 309.483 195.009 309.519C195.009 309.732 195.134 309.886 195.383 309.981C195.633 310.077 195.937 310.124 196.296 310.124ZM202.761 303.227C203.369 303.227 203.839 303.403 204.169 303.755C204.506 304.107 204.675 304.61 204.675 305.262V308.76H203.355V305.592C203.355 305.182 203.274 304.877 203.113 304.679C202.951 304.481 202.698 304.382 202.354 304.382C201.921 304.382 201.606 304.558 201.408 304.91C201.217 305.255 201.122 305.816 201.122 306.593V308.76H199.802V301.093H201.122V303.953C201.496 303.469 202.042 303.227 202.761 303.227ZM207.636 304.382V307.143C207.636 307.356 207.695 307.514 207.812 307.616C207.937 307.719 208.109 307.77 208.329 307.77C208.513 307.77 208.733 307.73 208.989 307.649V308.705C208.659 308.815 208.329 308.87 207.999 308.87C207.508 308.87 207.105 308.738 206.789 308.474C206.474 308.203 206.316 307.792 206.316 307.242V304.382H205.436V303.337H206.316V302.072L207.636 301.093V303.337H208.989V304.382H207.636ZM211.969 308.87C211.419 308.87 210.935 308.727 210.517 308.441C210.107 308.148 209.832 307.785 209.692 307.352L210.748 306.879C210.961 307.473 211.346 307.77 211.903 307.77C212.189 307.77 212.406 307.704 212.552 307.572C212.706 307.44 212.783 307.294 212.783 307.132C212.783 306.971 212.706 306.85 212.552 306.769C212.398 306.689 212.145 306.597 211.793 306.494C211.427 306.399 211.122 306.3 210.88 306.197C210.638 306.087 210.429 305.922 210.253 305.702C210.077 305.475 209.989 305.178 209.989 304.811C209.989 304.313 210.18 303.924 210.561 303.645C210.95 303.367 211.423 303.227 211.98 303.227C212.442 303.227 212.849 303.33 213.201 303.535C213.553 303.741 213.832 304.03 214.037 304.404L213.014 304.965C212.904 304.76 212.765 304.595 212.596 304.47C212.428 304.338 212.208 304.272 211.936 304.272C211.731 304.272 211.562 304.316 211.43 304.404C211.306 304.492 211.243 304.602 211.243 304.734C211.243 304.881 211.32 304.995 211.474 305.075C211.636 305.156 211.881 305.24 212.211 305.328C212.593 305.438 212.908 305.548 213.157 305.658C213.407 305.768 213.623 305.937 213.806 306.164C213.99 306.392 214.081 306.689 214.081 307.055C214.081 307.459 213.979 307.796 213.773 308.067C213.575 308.339 213.315 308.54 212.992 308.672C212.67 308.804 212.329 308.87 211.969 308.87Z" fill="black" /> <g class="al-2023-active-dots green" id="active dots_12"> <circle id="Ellipse 2765_12" cx="195.664" cy="333.508" r="48.5676" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2767_12" cx="195.665" cy="333.508" r="25.309" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2771_12" cx="195.665" cy="333.508" r="13.0446" fill="white" stroke="#22704F" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot green" id="inactive dot_12" cx="195.664" cy="333.508" r="10.2374" fill="#22704F" stroke="white" stroke-width="3" /> <circle class="overlay-dot green" id="inactive dot_12" cx="195.664" cy="333.508" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="9-COVID-19-Tissue-Atlas" data-milestone="covid-19-tissue-atlas" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_32" d="M767.043 284.268L551.494 284.268C542.106 284.268 534.494 276.657 534.494 267.268V166.599C534.494 155.553 525.54 146.599 514.494 146.599H443.75" stroke="url(#paint13_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_35" d="M767.045 287.747L545.869 287.747C540.034 287.747 534.607 284.754 531.493 279.82L511.614 248.325C507.951 242.52 501.566 239 494.701 239H346.742" stroke="url(#paint14_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" id="connector-line_36" d="M630.375 101.969L775.635 289.025" stroke="#004375" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M761.077 253.829C760.329 253.829 759.673 253.667 759.108 253.345C758.551 253.015 758.118 252.549 757.81 251.948C757.51 251.339 757.359 250.631 757.359 249.825C757.359 249.018 757.51 248.314 757.81 247.713C758.118 247.104 758.551 246.638 759.108 246.316C759.673 245.986 760.329 245.821 761.077 245.821C761.891 245.821 762.592 246.015 763.178 246.404C763.765 246.785 764.198 247.339 764.476 248.065L763.211 248.56C763.043 248.083 762.775 247.727 762.408 247.493C762.049 247.251 761.605 247.13 761.077 247.13C760.337 247.13 759.761 247.364 759.35 247.834C758.94 248.296 758.734 248.956 758.734 249.814C758.734 250.672 758.94 251.339 759.35 251.816C759.761 252.285 760.337 252.52 761.077 252.52C761.605 252.52 762.053 252.399 762.419 252.157C762.786 251.907 763.05 251.541 763.211 251.057L764.498 251.541C764.227 252.281 763.794 252.85 763.2 253.246C762.606 253.634 761.899 253.829 761.077 253.829ZM768.746 253.829C768.027 253.829 767.389 253.664 766.832 253.334C766.282 252.996 765.853 252.527 765.545 251.926C765.237 251.324 765.083 250.628 765.083 249.836C765.083 249.044 765.237 248.347 765.545 247.746C765.853 247.137 766.282 246.668 766.832 246.338C767.389 246 768.027 245.832 768.746 245.832C769.472 245.832 770.11 246 770.66 246.338C771.217 246.668 771.646 247.137 771.947 247.746C772.255 248.347 772.409 249.044 772.409 249.836C772.409 250.628 772.255 251.324 771.947 251.926C771.639 252.527 771.206 252.996 770.649 253.334C770.099 253.664 769.465 253.829 768.746 253.829ZM768.746 252.52C769.443 252.52 769.996 252.278 770.407 251.794C770.825 251.31 771.034 250.657 771.034 249.836C771.034 249.007 770.825 248.351 770.407 247.867C769.996 247.383 769.443 247.141 768.746 247.141C768.042 247.141 767.485 247.383 767.074 247.867C766.663 248.343 766.458 249 766.458 249.836C766.458 250.664 766.663 251.321 767.074 251.805C767.485 252.281 768.042 252.52 768.746 252.52ZM779.755 245.997L776.697 253.664H775.663L772.594 245.997H774.112L776.18 251.42L778.237 245.997H779.755ZM780.769 245.997H782.144V253.664H780.769V245.997ZM784.077 245.997H786.299C787.568 245.997 788.551 246.338 789.247 247.02C789.944 247.694 790.292 248.651 790.292 249.891C790.292 251.115 789.948 252.05 789.258 252.696C788.576 253.341 787.586 253.664 786.288 253.664H784.077V245.997ZM786.156 252.399C787.124 252.399 787.825 252.197 788.257 251.794C788.69 251.39 788.906 250.738 788.906 249.836C788.906 248.948 788.694 248.299 788.268 247.889C787.85 247.471 787.187 247.262 786.277 247.262H785.452V252.399H786.156ZM791.463 249.913H794.631V250.903H791.463V249.913ZM799.766 245.997V253.664H798.446V248.296H796.653V247.196H797.676C797.94 247.196 798.134 247.137 798.259 247.02C798.384 246.902 798.446 246.715 798.446 246.459V245.997H799.766ZM805.034 245.887C805.54 245.887 806.006 246.008 806.431 246.25C806.864 246.484 807.205 246.807 807.454 247.218C807.711 247.628 807.839 248.072 807.839 248.549C807.839 249.047 807.696 249.524 807.41 249.979L805.122 253.664H803.604L805.177 251.244C804.789 251.266 804.407 251.203 804.033 251.057C803.513 250.859 803.084 250.536 802.746 250.089C802.416 249.634 802.251 249.124 802.251 248.56C802.251 248.076 802.376 247.628 802.625 247.218C802.875 246.807 803.212 246.484 803.637 246.25C804.07 246.008 804.536 245.887 805.034 245.887ZM805.034 249.968C805.298 249.968 805.54 249.905 805.76 249.781C805.988 249.649 806.164 249.476 806.288 249.264C806.42 249.051 806.486 248.816 806.486 248.56C806.486 248.303 806.42 248.068 806.288 247.856C806.164 247.643 805.988 247.474 805.76 247.35C805.54 247.218 805.298 247.152 805.034 247.152C804.77 247.152 804.528 247.218 804.308 247.35C804.088 247.474 803.912 247.643 803.78 247.856C803.656 248.068 803.593 248.303 803.593 248.56C803.593 248.816 803.656 249.051 803.78 249.264C803.912 249.476 804.088 249.649 804.308 249.781C804.528 249.905 804.77 249.968 805.034 249.968ZM759.427 259.262H757.029V257.997H763.211V259.262H760.813V265.664H759.427V259.262ZM763.985 260.241H765.305V265.664H763.985V260.241ZM763.952 257.997H765.338V259.218H763.952V257.997ZM768.547 265.774C767.997 265.774 767.513 265.631 767.095 265.345C766.685 265.051 766.41 264.688 766.27 264.256L767.326 263.783C767.539 264.377 767.924 264.674 768.481 264.674C768.767 264.674 768.984 264.608 769.13 264.476C769.284 264.344 769.361 264.197 769.361 264.036C769.361 263.874 769.284 263.753 769.13 263.673C768.976 263.592 768.723 263.5 768.371 263.398C768.005 263.302 767.7 263.203 767.458 263.101C767.216 262.991 767.007 262.826 766.831 262.606C766.655 262.378 766.567 262.081 766.567 261.715C766.567 261.216 766.758 260.827 767.139 260.549C767.528 260.27 768.001 260.131 768.558 260.131C769.02 260.131 769.427 260.233 769.779 260.439C770.131 260.644 770.41 260.934 770.615 261.308L769.592 261.869C769.482 261.663 769.343 261.498 769.174 261.374C769.006 261.242 768.786 261.176 768.514 261.176C768.309 261.176 768.14 261.22 768.008 261.308C767.884 261.396 767.821 261.506 767.821 261.638C767.821 261.784 767.898 261.898 768.052 261.979C768.214 262.059 768.459 262.144 768.789 262.232C769.171 262.342 769.486 262.452 769.735 262.562C769.985 262.672 770.201 262.84 770.384 263.068C770.568 263.295 770.659 263.592 770.659 263.959C770.659 264.362 770.557 264.699 770.351 264.971C770.153 265.242 769.893 265.444 769.57 265.576C769.248 265.708 768.907 265.774 768.547 265.774ZM773.478 265.774C772.928 265.774 772.444 265.631 772.026 265.345C771.615 265.051 771.34 264.688 771.201 264.256L772.257 263.783C772.47 264.377 772.855 264.674 773.412 264.674C773.698 264.674 773.914 264.608 774.061 264.476C774.215 264.344 774.292 264.197 774.292 264.036C774.292 263.874 774.215 263.753 774.061 263.673C773.907 263.592 773.654 263.5 773.302 263.398C772.935 263.302 772.631 263.203 772.389 263.101C772.147 262.991 771.938 262.826 771.762 262.606C771.586 262.378 771.498 262.081 771.498 261.715C771.498 261.216 771.689 260.827 772.07 260.549C772.459 260.27 772.932 260.131 773.489 260.131C773.951 260.131 774.358 260.233 774.71 260.439C775.062 260.644 775.341 260.934 775.546 261.308L774.523 261.869C774.413 261.663 774.274 261.498 774.105 261.374C773.936 261.242 773.716 261.176 773.445 261.176C773.24 261.176 773.071 261.22 772.939 261.308C772.814 261.396 772.752 261.506 772.752 261.638C772.752 261.784 772.829 261.898 772.983 261.979C773.144 262.059 773.39 262.144 773.72 262.232C774.101 262.342 774.417 262.452 774.666 262.562C774.915 262.672 775.132 262.84 775.315 263.068C775.498 263.295 775.59 263.592 775.59 263.959C775.59 264.362 775.487 264.699 775.282 264.971C775.084 265.242 774.824 265.444 774.501 265.576C774.178 265.708 773.837 265.774 773.478 265.774ZM781.402 260.241V265.664H780.082V265.037C779.898 265.286 779.664 265.473 779.378 265.598C779.099 265.715 778.795 265.774 778.465 265.774C777.819 265.774 777.335 265.572 777.013 265.169C776.69 264.765 776.529 264.252 776.529 263.629V260.241H777.849V263.299C777.849 263.643 777.907 263.951 778.025 264.223C778.142 264.487 778.417 264.619 778.85 264.619C779.231 264.619 779.51 264.501 779.686 264.267C779.869 264.032 779.979 263.761 780.016 263.453C780.06 263.145 780.082 262.76 780.082 262.298V260.241H781.402ZM787.543 262.881C787.543 263.042 787.532 263.211 787.51 263.387H783.792C783.822 263.753 783.95 264.043 784.177 264.256C784.405 264.468 784.727 264.575 785.145 264.575C785.673 264.575 786.106 264.38 786.443 263.992L787.356 264.795C787.056 265.125 786.722 265.37 786.355 265.532C785.996 265.693 785.589 265.774 785.134 265.774C784.54 265.774 784.042 265.645 783.638 265.389C783.242 265.132 782.949 264.795 782.758 264.377C782.568 263.951 782.472 263.486 782.472 262.98C782.472 262.481 782.564 262.015 782.747 261.583C782.938 261.15 783.224 260.802 783.605 260.538C783.994 260.266 784.474 260.131 785.046 260.131C785.589 260.131 786.047 260.252 786.421 260.494C786.795 260.736 787.074 261.066 787.257 261.484C787.448 261.902 787.543 262.367 787.543 262.881ZM786.278 262.342C786.271 262.004 786.15 261.737 785.915 261.539C785.681 261.333 785.387 261.231 785.035 261.231C784.661 261.231 784.368 261.341 784.155 261.561C783.95 261.773 783.825 262.034 783.781 262.342H786.278ZM795.658 264.08H792.655L792.072 265.664H790.576L793.645 257.997H794.679L797.737 265.664H796.241L795.658 264.08ZM795.196 262.815L794.162 260.021L793.128 262.815H795.196ZM799.846 261.286V264.047C799.846 264.259 799.905 264.417 800.022 264.52C800.147 264.622 800.319 264.674 800.539 264.674C800.722 264.674 800.942 264.633 801.199 264.553V265.609C800.869 265.719 800.539 265.774 800.209 265.774C799.718 265.774 799.314 265.642 798.999 265.378C798.684 265.106 798.526 264.696 798.526 264.146V261.286H797.646V260.241H798.526V258.976L799.846 257.997V260.241H801.199V261.286H799.846ZM803.308 265.774C802.92 265.774 802.608 265.656 802.373 265.422C802.146 265.187 802.032 264.835 802.032 264.366V257.997H803.352V264.278C803.352 264.505 803.481 264.619 803.737 264.619C803.862 264.619 804.001 264.597 804.155 264.553V265.609C803.862 265.719 803.58 265.774 803.308 265.774ZM807.218 260.131C807.936 260.131 808.501 260.321 808.912 260.703C809.33 261.077 809.539 261.59 809.539 262.243V265.664H808.329L808.219 264.96C808.057 265.216 807.83 265.418 807.537 265.565C807.251 265.704 806.928 265.774 806.569 265.774C806.195 265.774 805.857 265.7 805.557 265.554C805.263 265.4 805.032 265.187 804.864 264.916C804.695 264.644 804.611 264.34 804.611 264.003C804.611 263.68 804.68 263.401 804.82 263.167C804.959 262.932 805.161 262.756 805.425 262.639C805.777 262.477 806.257 262.397 806.866 262.397H808.219V262.243C808.219 261.949 808.127 261.718 807.944 261.55C807.76 261.374 807.511 261.286 807.196 261.286C806.917 261.286 806.653 261.355 806.404 261.495C806.154 261.634 805.931 261.836 805.733 262.1L804.776 261.297C805.421 260.519 806.235 260.131 807.218 260.131ZM806.778 264.652C807.174 264.652 807.511 264.531 807.79 264.289C808.076 264.039 808.219 263.739 808.219 263.387H807.042C806.616 263.387 806.319 263.449 806.151 263.574C806.004 263.676 805.931 263.827 805.931 264.025C805.931 264.215 806.004 264.369 806.151 264.487C806.305 264.597 806.514 264.652 806.778 264.652ZM812.633 265.774C812.083 265.774 811.599 265.631 811.181 265.345C810.771 265.051 810.496 264.688 810.356 264.256L811.412 263.783C811.625 264.377 812.01 264.674 812.567 264.674C812.853 264.674 813.07 264.608 813.216 264.476C813.37 264.344 813.447 264.197 813.447 264.036C813.447 263.874 813.37 263.753 813.216 263.673C813.062 263.592 812.809 263.5 812.457 263.398C812.091 263.302 811.786 263.203 811.544 263.101C811.302 262.991 811.093 262.826 810.917 262.606C810.741 262.378 810.653 262.081 810.653 261.715C810.653 261.216 810.844 260.827 811.225 260.549C811.614 260.27 812.087 260.131 812.644 260.131C813.106 260.131 813.513 260.233 813.865 260.439C814.217 260.644 814.496 260.934 814.701 261.308L813.678 261.869C813.568 261.663 813.429 261.498 813.26 261.374C813.092 261.242 812.872 261.176 812.6 261.176C812.395 261.176 812.226 261.22 812.094 261.308C811.97 261.396 811.907 261.506 811.907 261.638C811.907 261.784 811.984 261.898 812.138 261.979C812.3 262.059 812.545 262.144 812.875 262.232C813.257 262.342 813.572 262.452 813.821 262.562C814.071 262.672 814.287 262.84 814.47 263.068C814.654 263.295 814.745 263.592 814.745 263.959C814.745 264.362 814.643 264.699 814.437 264.971C814.239 265.242 813.979 265.444 813.656 265.576C813.334 265.708 812.993 265.774 812.633 265.774Z" fill="black" /> <g class="al-2023-active-dots navy" id="active dots_13"> <circle id="Ellipse 2765_13" cx="776.371" cy="287.205" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_13" cx="776.371" cy="287.204" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_13" cx="776.371" cy="287.205" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive dot_13" cx="776.371" cy="287.204" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive dot_13" cx="776.371" cy="287.204" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="8-CELLxGENE-Discover" data-milestone="cellxgene-discover" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_37" d="M94.295 146.599V464.04C94.295 486.132 112.204 504.04 134.295 504.04H323.684C333.073 504.04 340.684 496.429 340.684 487.04V253" stroke="url(#paint15_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" d="M46.4189 214.133V469C46.4189 491.091 64.3276 509 86.4189 509H323.684C333.073 509 340.684 501.389 340.684 492V485" stroke="url(#paint16_linear_42_3042)" stroke-width="1.5" stroke-linecap="round"/> <g id="connector-line_39"> <path class="al-2023-connector-line" d="M143.198 194.336V468.296C143.198 484.864 156.629 498.296 173.198 498.296H323.684C333.073 498.296 340.684 490.685 340.684 481.296V472.87" stroke="black" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line" d="M143.198 194.336V468.296C143.198 484.864 156.629 498.296 173.198 498.296H323.684C333.073 498.296 340.684 490.685 340.684 481.296V472.87" stroke="#21704F" stroke-width="1.5" stroke-linecap="round" /> </g> <path class="al-2023-connector-line" id="connector-line_40" d="M446.518 145.385H357.684C348.295 145.385 340.684 152.996 340.684 162.385V246.992" stroke="#4BC1C0" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M264.461 242.031C263.713 242.031 263.056 241.87 262.492 241.547C261.934 241.217 261.502 240.752 261.194 240.15C260.893 239.542 260.743 238.834 260.743 238.027C260.743 237.221 260.893 236.517 261.194 235.915C261.502 235.307 261.934 234.841 262.492 234.518C263.056 234.188 263.713 234.023 264.461 234.023C265.275 234.023 265.975 234.218 266.562 234.606C267.148 234.988 267.581 235.541 267.86 236.267L266.595 236.762C266.426 236.286 266.158 235.93 265.792 235.695C265.432 235.453 264.989 235.332 264.461 235.332C263.72 235.332 263.144 235.567 262.734 236.036C262.323 236.498 262.118 237.158 262.118 238.016C262.118 238.874 262.323 239.542 262.734 240.018C263.144 240.488 263.72 240.722 264.461 240.722C264.989 240.722 265.436 240.601 265.803 240.359C266.169 240.11 266.433 239.743 266.595 239.259L267.882 239.743C267.61 240.484 267.178 241.052 266.584 241.448C265.99 241.837 265.282 242.031 264.461 242.031ZM269.091 234.199H274.195V235.464H270.466V237.29H273.931V238.555H270.466V240.601H274.195V241.866H269.091V234.199ZM275.805 234.199H277.18V240.601H280.458V241.866H275.805V234.199ZM281.52 234.199H282.895V240.601H286.173V241.866H281.52V234.199ZM288.159 239.138L286.3 236.443H287.917L289.039 238.236L290.161 236.443H291.778L289.908 239.138L291.778 241.866H290.161L289.039 240.04L287.917 241.866H286.3L288.159 239.138ZM299.411 237.719V241.866H298.432L298.267 241.074C298.04 241.382 297.728 241.621 297.332 241.789C296.943 241.951 296.5 242.031 296.001 242.031C295.29 242.031 294.644 241.866 294.065 241.536C293.493 241.199 293.042 240.726 292.712 240.117C292.382 239.509 292.217 238.808 292.217 238.016C292.217 237.254 292.367 236.572 292.668 235.97C292.976 235.362 293.412 234.885 293.977 234.54C294.549 234.196 295.209 234.023 295.957 234.023C296.749 234.023 297.438 234.218 298.025 234.606C298.619 234.995 299.055 235.549 299.334 236.267L298.069 236.762C297.9 236.293 297.633 235.937 297.266 235.695C296.899 235.453 296.456 235.332 295.935 235.332C295.194 235.332 294.619 235.567 294.208 236.036C293.797 236.506 293.592 237.162 293.592 238.005C293.592 238.871 293.812 239.542 294.252 240.018C294.692 240.488 295.304 240.722 296.089 240.722C296.705 240.722 297.185 240.579 297.53 240.293C297.875 240 298.047 239.597 298.047 239.083V238.984H296.331V237.719H299.411ZM301.06 234.199H306.164V235.464H302.435V237.29H305.9V238.555H302.435V240.601H306.164V241.866H301.06V234.199ZM313.791 234.199V241.866H312.361L309.149 236.564V241.866H307.774V234.199H309.193L312.416 239.479V234.199H313.791ZM315.723 234.199H320.827V235.464H317.098V237.29H320.563V238.555H317.098V240.601H320.827V241.866H315.723V234.199ZM280.435 247.199H282.657C283.926 247.199 284.908 247.54 285.605 248.222C286.302 248.897 286.65 249.854 286.65 251.093C286.65 252.318 286.305 253.253 285.616 253.898C284.934 254.544 283.944 254.866 282.646 254.866H280.435V247.199ZM282.514 253.601C283.482 253.601 284.182 253.4 284.615 252.996C285.048 252.593 285.264 251.94 285.264 251.038C285.264 250.151 285.051 249.502 284.626 249.091C284.208 248.673 283.544 248.464 282.635 248.464H281.81V253.601H282.514ZM287.843 249.443H289.163V254.866H287.843V249.443ZM287.81 247.199H289.196V248.42H287.81V247.199ZM292.405 254.976C291.855 254.976 291.371 254.833 290.953 254.547C290.542 254.254 290.267 253.891 290.128 253.458L291.184 252.985C291.397 253.579 291.782 253.876 292.339 253.876C292.625 253.876 292.841 253.81 292.988 253.678C293.142 253.546 293.219 253.4 293.219 253.238C293.219 253.077 293.142 252.956 292.988 252.875C292.834 252.795 292.581 252.703 292.229 252.6C291.862 252.505 291.558 252.406 291.316 252.303C291.074 252.193 290.865 252.028 290.689 251.808C290.513 251.581 290.425 251.284 290.425 250.917C290.425 250.419 290.616 250.03 290.997 249.751C291.386 249.473 291.859 249.333 292.416 249.333C292.878 249.333 293.285 249.436 293.637 249.641C293.989 249.847 294.268 250.136 294.473 250.51L293.45 251.071C293.34 250.866 293.201 250.701 293.032 250.576C292.863 250.444 292.643 250.378 292.372 250.378C292.167 250.378 291.998 250.422 291.866 250.51C291.741 250.598 291.679 250.708 291.679 250.84C291.679 250.987 291.756 251.101 291.91 251.181C292.071 251.262 292.317 251.346 292.647 251.434C293.028 251.544 293.344 251.654 293.593 251.764C293.842 251.874 294.059 252.043 294.242 252.27C294.425 252.498 294.517 252.795 294.517 253.161C294.517 253.565 294.414 253.902 294.209 254.173C294.011 254.445 293.751 254.646 293.428 254.778C293.105 254.91 292.764 254.976 292.405 254.976ZM297.765 254.976C297.201 254.976 296.72 254.848 296.324 254.591C295.928 254.327 295.631 253.983 295.433 253.557C295.235 253.125 295.136 252.663 295.136 252.171C295.136 251.673 295.235 251.211 295.433 250.785C295.631 250.353 295.925 250.004 296.313 249.74C296.709 249.469 297.19 249.333 297.754 249.333C298.304 249.333 298.781 249.469 299.184 249.74C299.588 250.004 299.892 250.4 300.097 250.928L298.843 251.423C298.77 251.137 298.634 250.91 298.436 250.741C298.246 250.573 298.018 250.488 297.754 250.488C297.329 250.488 297.01 250.65 296.797 250.972C296.592 251.295 296.489 251.695 296.489 252.171C296.489 252.648 296.592 253.044 296.797 253.359C297.003 253.667 297.322 253.821 297.754 253.821C298.018 253.821 298.246 253.741 298.436 253.579C298.634 253.411 298.77 253.187 298.843 252.908L300.042 253.37C299.859 253.876 299.566 254.272 299.162 254.558C298.766 254.837 298.301 254.976 297.765 254.976ZM303.224 254.976C302.681 254.976 302.201 254.852 301.783 254.602C301.372 254.346 301.057 254.001 300.837 253.568C300.617 253.136 300.507 252.663 300.507 252.149C300.507 251.636 300.617 251.167 300.837 250.741C301.057 250.309 301.372 249.968 301.783 249.718C302.201 249.462 302.681 249.333 303.224 249.333C303.767 249.333 304.243 249.462 304.654 249.718C305.065 249.968 305.38 250.309 305.6 250.741C305.827 251.167 305.941 251.636 305.941 252.149C305.941 252.663 305.827 253.136 305.6 253.568C305.38 254.001 305.065 254.346 304.654 254.602C304.243 254.852 303.767 254.976 303.224 254.976ZM303.224 253.821C303.693 253.821 304.042 253.664 304.269 253.348C304.504 253.033 304.621 252.633 304.621 252.149C304.621 251.665 304.504 251.269 304.269 250.961C304.042 250.646 303.693 250.488 303.224 250.488C302.755 250.488 302.403 250.646 302.168 250.961C301.941 251.269 301.827 251.665 301.827 252.149C301.827 252.633 301.941 253.033 302.168 253.348C302.403 253.664 302.755 253.821 303.224 253.821ZM306.01 249.443H307.451L308.76 253.15L310.091 249.443H311.521L309.31 254.866H308.221L306.01 249.443ZM316.697 252.083C316.697 252.245 316.686 252.413 316.664 252.589H312.946C312.975 252.956 313.104 253.246 313.331 253.458C313.558 253.671 313.881 253.777 314.299 253.777C314.827 253.777 315.26 253.583 315.597 253.194L316.51 253.997C316.209 254.327 315.876 254.573 315.509 254.734C315.15 254.896 314.743 254.976 314.288 254.976C313.694 254.976 313.195 254.848 312.792 254.591C312.396 254.335 312.103 253.997 311.912 253.579C311.721 253.154 311.626 252.688 311.626 252.182C311.626 251.684 311.718 251.218 311.901 250.785C312.092 250.353 312.378 250.004 312.759 249.74C313.148 249.469 313.628 249.333 314.2 249.333C314.743 249.333 315.201 249.454 315.575 249.696C315.949 249.938 316.228 250.268 316.411 250.686C316.602 251.104 316.697 251.57 316.697 252.083ZM315.432 251.544C315.425 251.207 315.304 250.939 315.069 250.741C314.834 250.536 314.541 250.433 314.189 250.433C313.815 250.433 313.522 250.543 313.309 250.763C313.104 250.976 312.979 251.236 312.935 251.544H315.432ZM320.564 249.333C320.923 249.333 321.268 249.436 321.598 249.641L320.96 250.807C320.769 250.683 320.549 250.62 320.3 250.62C319.501 250.62 319.101 251.126 319.101 252.138V254.866H317.781V249.443H319.112V250.367C319.222 250.045 319.409 249.792 319.673 249.608C319.944 249.425 320.241 249.333 320.564 249.333Z" fill="black" /> <g class="al-2023-active-dots turqiose" id="active dots_14"> <circle id="Ellipse 2765_14" cx="341.088" cy="242.444" r="48.5676" fill="#74FFFE" fill-opacity="0.1" /> <circle id="Ellipse 2767_14" cx="341.088" cy="242.444" r="25.309" fill="#74FFFE" fill-opacity="0.4" /> <circle id="Ellipse 2771_14" cx="341.088" cy="242.444" r="13.0446" fill="white" stroke="#73DAD9" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot turqiose" id="inactive dot_14" cx="341.088" cy="242.607" r="10.2374" fill="#73DAD9" stroke="white" stroke-width="3" /> <circle class="overlay-dot turqiose" id="inactive dot_14" cx="341.088" cy="242.607" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="7-Seed-Networks-for-a-Human-Cell-Atlas" data-milestone="seed-networks-for-a-human-cell-atlas" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" d="M46.4424 150.461L46.4424 209.837C46.4424 215.36 50.9195 219.837 56.4424 219.837L98.9666 219.837L133.198 219.837C138.721 219.837 143.198 215.36 143.198 209.837L143.198 198.232" stroke="#22704F" stroke-width="1.5" stroke-linecap="round"/> <path class="al-2023-connector-line" d="M94.3467 146.117H128.001C136.782 146.117 143.923 153.195 144 161.976L144.294 195.196" stroke="#22704F" stroke-width="1.5" stroke-linecap="round"/> <path class="al-2023-connector-line" id="connector-line_41" d="M239.15 101.636L144.362 196.424" stroke="#22704F" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M167.909 192.408C167.403 192.408 166.941 192.313 166.523 192.122C166.105 191.932 165.76 191.664 165.489 191.319C165.218 190.967 165.045 190.56 164.972 190.098L166.336 189.757C166.387 190.212 166.552 190.564 166.831 190.813C167.117 191.063 167.484 191.187 167.931 191.187C168.32 191.187 168.628 191.096 168.855 190.912C169.082 190.729 169.196 190.476 169.196 190.153C169.196 189.889 169.082 189.662 168.855 189.471C168.635 189.281 168.239 189.072 167.667 188.844C167.124 188.632 166.695 188.419 166.38 188.206C166.065 187.994 165.837 187.755 165.698 187.491C165.559 187.22 165.489 186.897 165.489 186.523C165.489 186.113 165.588 185.75 165.786 185.434C165.984 185.119 166.263 184.873 166.622 184.697C166.989 184.521 167.407 184.433 167.876 184.433C168.397 184.433 168.855 184.551 169.251 184.785C169.647 185.02 169.966 185.368 170.208 185.83L169.064 186.534C168.932 186.248 168.76 186.032 168.547 185.885C168.334 185.731 168.096 185.654 167.832 185.654C167.561 185.654 167.33 185.735 167.139 185.896C166.956 186.058 166.864 186.256 166.864 186.49C166.864 186.74 166.974 186.952 167.194 187.128C167.414 187.304 167.81 187.506 168.382 187.733C168.939 187.946 169.376 188.159 169.691 188.371C170.006 188.584 170.23 188.822 170.362 189.086C170.501 189.343 170.571 189.658 170.571 190.032C170.571 190.502 170.457 190.916 170.23 191.275C170.01 191.635 169.698 191.913 169.295 192.111C168.892 192.309 168.43 192.408 167.909 192.408ZM176.211 189.482C176.211 189.644 176.2 189.812 176.178 189.988H172.46C172.489 190.355 172.618 190.645 172.845 190.857C173.072 191.07 173.395 191.176 173.813 191.176C174.341 191.176 174.774 190.982 175.111 190.593L176.024 191.396C175.723 191.726 175.39 191.972 175.023 192.133C174.664 192.295 174.257 192.375 173.802 192.375C173.208 192.375 172.709 192.247 172.306 191.99C171.91 191.734 171.617 191.396 171.426 190.978C171.235 190.553 171.14 190.087 171.14 189.581C171.14 189.083 171.232 188.617 171.415 188.184C171.606 187.752 171.892 187.403 172.273 187.139C172.662 186.868 173.142 186.732 173.714 186.732C174.257 186.732 174.715 186.853 175.089 187.095C175.463 187.337 175.742 187.667 175.925 188.085C176.116 188.503 176.211 188.969 176.211 189.482ZM174.946 188.943C174.939 188.606 174.818 188.338 174.583 188.14C174.348 187.935 174.055 187.832 173.703 187.832C173.329 187.832 173.036 187.942 172.823 188.162C172.618 188.375 172.493 188.635 172.449 188.943H174.946ZM181.915 189.482C181.915 189.644 181.904 189.812 181.882 189.988H178.164C178.193 190.355 178.322 190.645 178.549 190.857C178.776 191.07 179.099 191.176 179.517 191.176C180.045 191.176 180.478 190.982 180.815 190.593L181.728 191.396C181.427 191.726 181.094 191.972 180.727 192.133C180.368 192.295 179.961 192.375 179.506 192.375C178.912 192.375 178.413 192.247 178.01 191.99C177.614 191.734 177.321 191.396 177.13 190.978C176.939 190.553 176.844 190.087 176.844 189.581C176.844 189.083 176.936 188.617 177.119 188.184C177.31 187.752 177.596 187.403 177.977 187.139C178.366 186.868 178.846 186.732 179.418 186.732C179.961 186.732 180.419 186.853 180.793 187.095C181.167 187.337 181.446 187.667 181.629 188.085C181.82 188.503 181.915 188.969 181.915 189.482ZM180.65 188.943C180.643 188.606 180.522 188.338 180.287 188.14C180.052 187.935 179.759 187.832 179.407 187.832C179.033 187.832 178.74 187.942 178.527 188.162C178.322 188.375 178.197 188.635 178.153 188.943H180.65ZM187.751 184.598V192.265H186.431V191.726C186.255 191.946 186.028 192.111 185.749 192.221C185.471 192.324 185.177 192.375 184.869 192.375C184.151 192.375 183.59 192.115 183.186 191.594C182.783 191.066 182.581 190.384 182.581 189.548C182.581 188.969 182.677 188.467 182.867 188.041C183.065 187.616 183.337 187.293 183.681 187.073C184.026 186.846 184.422 186.732 184.869 186.732C185.177 186.732 185.471 186.791 185.749 186.908C186.035 187.026 186.263 187.187 186.431 187.392V184.598H187.751ZM185.188 191.154C185.643 191.154 185.984 191.008 186.211 190.714C186.439 190.421 186.552 190.036 186.552 189.559C186.552 189.075 186.439 188.683 186.211 188.382C185.984 188.082 185.647 187.931 185.199 187.931C184.767 187.931 184.44 188.074 184.22 188.36C184.008 188.639 183.901 189.039 183.901 189.559C183.901 190.073 184.008 190.469 184.22 190.747C184.433 191.019 184.756 191.154 185.188 191.154ZM198.195 184.598V192.265H196.765L193.553 186.963V192.265H192.178V184.598H193.597L196.82 189.878V184.598H198.195ZM204.517 189.482C204.517 189.644 204.506 189.812 204.484 189.988H200.766C200.795 190.355 200.923 190.645 201.151 190.857C201.378 191.07 201.701 191.176 202.119 191.176C202.647 191.176 203.079 190.982 203.417 190.593L204.33 191.396C204.029 191.726 203.695 191.972 203.329 192.133C202.969 192.295 202.562 192.375 202.108 192.375C201.514 192.375 201.015 192.247 200.612 191.99C200.216 191.734 199.922 191.396 199.732 190.978C199.541 190.553 199.446 190.087 199.446 189.581C199.446 189.083 199.537 188.617 199.721 188.184C199.911 187.752 200.197 187.403 200.579 187.139C200.967 186.868 201.448 186.732 202.02 186.732C202.562 186.732 203.021 186.853 203.395 187.095C203.769 187.337 204.047 187.667 204.231 188.085C204.421 188.503 204.517 188.969 204.517 189.482ZM203.252 188.943C203.244 188.606 203.123 188.338 202.889 188.14C202.654 187.935 202.361 187.832 202.009 187.832C201.635 187.832 201.341 187.942 201.129 188.162C200.923 188.375 200.799 188.635 200.755 188.943H203.252ZM207.141 187.887V190.648C207.141 190.861 207.199 191.019 207.317 191.121C207.441 191.224 207.614 191.275 207.834 191.275C208.017 191.275 208.237 191.235 208.494 191.154V192.21C208.164 192.32 207.834 192.375 207.504 192.375C207.012 192.375 206.609 192.243 206.294 191.979C205.978 191.708 205.821 191.297 205.821 190.747V187.887H204.941V186.842H205.821V185.577L207.141 184.598V186.842H208.494V187.887H207.141ZM208.935 186.842H210.343L211.267 190.241L212.29 186.842H213.423L214.446 190.23L215.381 186.842H216.789L215.117 192.265H213.929L212.862 188.712L211.795 192.265H210.607L208.935 186.842ZM219.693 192.375C219.151 192.375 218.67 192.251 218.252 192.001C217.842 191.745 217.526 191.4 217.306 190.967C217.086 190.535 216.976 190.062 216.976 189.548C216.976 189.035 217.086 188.566 217.306 188.14C217.526 187.708 217.842 187.367 218.252 187.117C218.67 186.861 219.151 186.732 219.693 186.732C220.236 186.732 220.713 186.861 221.123 187.117C221.534 187.367 221.849 187.708 222.069 188.14C222.297 188.566 222.41 189.035 222.41 189.548C222.41 190.062 222.297 190.535 222.069 190.967C221.849 191.4 221.534 191.745 221.123 192.001C220.713 192.251 220.236 192.375 219.693 192.375ZM219.693 191.22C220.163 191.22 220.511 191.063 220.738 190.747C220.973 190.432 221.09 190.032 221.09 189.548C221.09 189.064 220.973 188.668 220.738 188.36C220.511 188.045 220.163 187.887 219.693 187.887C219.224 187.887 218.872 188.045 218.637 188.36C218.41 188.668 218.296 189.064 218.296 189.548C218.296 190.032 218.41 190.432 218.637 190.747C218.872 191.063 219.224 191.22 219.693 191.22ZM226.248 186.732C226.607 186.732 226.952 186.835 227.282 187.04L226.644 188.206C226.453 188.082 226.233 188.019 225.984 188.019C225.185 188.019 224.785 188.525 224.785 189.537V192.265H223.465V186.842H224.796V187.766C224.906 187.444 225.093 187.191 225.357 187.007C225.628 186.824 225.925 186.732 226.248 186.732ZM227.966 184.598H229.286V189.042L231.277 186.842H233.048L231.024 188.943L233.279 192.265H231.706L230.122 189.757L229.286 190.681V192.265H227.966V184.598ZM235.687 192.375C235.137 192.375 234.653 192.232 234.235 191.946C233.824 191.653 233.549 191.29 233.41 190.857L234.466 190.384C234.678 190.978 235.063 191.275 235.621 191.275C235.907 191.275 236.123 191.209 236.27 191.077C236.424 190.945 236.501 190.799 236.501 190.637C236.501 190.476 236.424 190.355 236.27 190.274C236.116 190.194 235.863 190.102 235.511 189.999C235.144 189.904 234.84 189.805 234.598 189.702C234.356 189.592 234.147 189.427 233.971 189.207C233.795 188.98 233.707 188.683 233.707 188.316C233.707 187.818 233.897 187.429 234.279 187.15C234.667 186.872 235.14 186.732 235.698 186.732C236.16 186.732 236.567 186.835 236.919 187.04C237.271 187.246 237.549 187.535 237.755 187.909L236.732 188.47C236.622 188.265 236.482 188.1 236.314 187.975C236.145 187.843 235.925 187.777 235.654 187.777C235.448 187.777 235.28 187.821 235.148 187.909C235.023 187.997 234.961 188.107 234.961 188.239C234.961 188.386 235.038 188.5 235.192 188.58C235.353 188.661 235.599 188.745 235.929 188.833C236.31 188.943 236.625 189.053 236.875 189.163C237.124 189.273 237.34 189.442 237.524 189.669C237.707 189.897 237.799 190.194 237.799 190.56C237.799 190.964 237.696 191.301 237.491 191.572C237.293 191.844 237.032 192.045 236.71 192.177C236.387 192.309 236.046 192.375 235.687 192.375ZM241.906 187.887H240.872V186.842H241.917V186.226C241.917 185.068 242.463 184.488 243.556 184.488C243.923 184.488 244.264 184.562 244.579 184.708L244.15 185.72C244.011 185.632 243.86 185.588 243.699 185.588C243.494 185.588 243.362 185.651 243.303 185.775C243.252 185.9 243.226 186.047 243.226 186.215V186.842H244.491V187.887H243.226V192.265H241.906V187.887ZM247.344 192.375C246.801 192.375 246.321 192.251 245.903 192.001C245.492 191.745 245.177 191.4 244.957 190.967C244.737 190.535 244.627 190.062 244.627 189.548C244.627 189.035 244.737 188.566 244.957 188.14C245.177 187.708 245.492 187.367 245.903 187.117C246.321 186.861 246.801 186.732 247.344 186.732C247.886 186.732 248.363 186.861 248.774 187.117C249.184 187.367 249.5 187.708 249.72 188.14C249.947 188.566 250.061 189.035 250.061 189.548C250.061 190.062 249.947 190.535 249.72 190.967C249.5 191.4 249.184 191.745 248.774 192.001C248.363 192.251 247.886 192.375 247.344 192.375ZM247.344 191.22C247.813 191.22 248.161 191.063 248.389 190.747C248.623 190.432 248.741 190.032 248.741 189.548C248.741 189.064 248.623 188.668 248.389 188.36C248.161 188.045 247.813 187.887 247.344 187.887C246.874 187.887 246.522 188.045 246.288 188.36C246.06 188.668 245.947 189.064 245.947 189.548C245.947 190.032 246.06 190.432 246.288 190.747C246.522 191.063 246.874 191.22 247.344 191.22ZM253.898 186.732C254.258 186.732 254.602 186.835 254.932 187.04L254.294 188.206C254.104 188.082 253.884 188.019 253.634 188.019C252.835 188.019 252.435 188.525 252.435 189.537V192.265H251.115V186.842H252.446V187.766C252.556 187.444 252.743 187.191 253.007 187.007C253.279 186.824 253.576 186.732 253.898 186.732ZM260.349 186.732C261.068 186.732 261.633 186.923 262.043 187.304C262.461 187.678 262.67 188.192 262.67 188.844V192.265H261.46L261.35 191.561C261.189 191.818 260.962 192.02 260.668 192.166C260.382 192.306 260.06 192.375 259.7 192.375C259.326 192.375 258.989 192.302 258.688 192.155C258.395 192.001 258.164 191.789 257.995 191.517C257.827 191.246 257.742 190.942 257.742 190.604C257.742 190.282 257.812 190.003 257.951 189.768C258.091 189.534 258.292 189.358 258.556 189.24C258.908 189.079 259.389 188.998 259.997 188.998H261.35V188.844C261.35 188.551 261.259 188.32 261.075 188.151C260.892 187.975 260.643 187.887 260.327 187.887C260.049 187.887 259.785 187.957 259.535 188.096C259.286 188.236 259.062 188.437 258.864 188.701L257.907 187.898C258.553 187.121 259.367 186.732 260.349 186.732ZM259.909 191.253C260.305 191.253 260.643 191.132 260.921 190.89C261.207 190.641 261.35 190.34 261.35 189.988H260.173C259.748 189.988 259.451 190.051 259.282 190.175C259.136 190.278 259.062 190.428 259.062 190.626C259.062 190.817 259.136 190.971 259.282 191.088C259.436 191.198 259.645 191.253 259.909 191.253ZM165.709 196.598H167.084V199.689H170.439V196.598H171.814V204.265H170.439V200.954H167.084V204.265H165.709V196.598ZM178.298 198.842V204.265H176.978V203.638C176.795 203.888 176.56 204.075 176.274 204.199C175.995 204.317 175.691 204.375 175.361 204.375C174.716 204.375 174.232 204.174 173.909 203.77C173.586 203.367 173.425 202.854 173.425 202.23V198.842H174.745V201.9C174.745 202.245 174.804 202.553 174.921 202.824C175.038 203.088 175.313 203.22 175.746 203.22C176.127 203.22 176.406 203.103 176.582 202.868C176.765 202.634 176.875 202.362 176.912 202.054C176.956 201.746 176.978 201.361 176.978 200.899V198.842H178.298ZM185.902 198.732C186.518 198.732 186.987 198.934 187.31 199.337C187.633 199.733 187.794 200.225 187.794 200.811V204.265H186.474V201.207C186.474 200.327 186.166 199.887 185.55 199.887C185.205 199.887 184.956 199.997 184.802 200.217C184.648 200.43 184.556 200.683 184.527 200.976C184.498 201.262 184.483 201.669 184.483 202.197V204.265H183.163V201.207C183.163 200.327 182.859 199.887 182.25 199.887C181.905 199.887 181.656 199.997 181.502 200.217C181.348 200.43 181.253 200.687 181.216 200.987C181.187 201.281 181.172 201.684 181.172 202.197V204.265H179.852L179.841 198.842H181.117V199.524C181.425 198.996 181.909 198.732 182.569 198.732C182.906 198.732 183.214 198.813 183.493 198.974C183.779 199.136 183.999 199.411 184.153 199.799C184.351 199.418 184.597 199.147 184.89 198.985C185.183 198.817 185.521 198.732 185.902 198.732ZM191.298 198.732C192.017 198.732 192.582 198.923 192.992 199.304C193.41 199.678 193.619 200.192 193.619 200.844V204.265H192.409L192.299 203.561C192.138 203.818 191.911 204.02 191.617 204.166C191.331 204.306 191.009 204.375 190.649 204.375C190.275 204.375 189.938 204.302 189.637 204.155C189.344 204.001 189.113 203.789 188.944 203.517C188.776 203.246 188.691 202.942 188.691 202.604C188.691 202.282 188.761 202.003 188.9 201.768C189.04 201.534 189.241 201.358 189.505 201.24C189.857 201.079 190.338 200.998 190.946 200.998H192.299V200.844C192.299 200.551 192.208 200.32 192.024 200.151C191.841 199.975 191.592 199.887 191.276 199.887C190.998 199.887 190.734 199.957 190.484 200.096C190.235 200.236 190.011 200.437 189.813 200.701L188.856 199.898C189.502 199.121 190.316 198.732 191.298 198.732ZM190.858 203.253C191.254 203.253 191.592 203.132 191.87 202.89C192.156 202.641 192.299 202.34 192.299 201.988H191.122C190.697 201.988 190.4 202.051 190.231 202.175C190.085 202.278 190.011 202.428 190.011 202.626C190.011 202.817 190.085 202.971 190.231 203.088C190.385 203.198 190.594 203.253 190.858 203.253ZM197.968 198.732C198.577 198.732 199.046 198.912 199.376 199.271C199.713 199.623 199.882 200.122 199.882 200.767V204.265H198.562V201.097C198.562 200.767 198.503 200.485 198.386 200.25C198.269 200.008 197.994 199.887 197.561 199.887C197.18 199.887 196.897 199.997 196.714 200.217C196.538 200.43 196.428 200.687 196.384 200.987C196.347 201.281 196.329 201.651 196.329 202.098V204.265H195.009V198.842H196.329V199.469C196.512 199.22 196.743 199.037 197.022 198.919C197.308 198.795 197.623 198.732 197.968 198.732ZM207.345 204.43C206.597 204.43 205.94 204.269 205.376 203.946C204.818 203.616 204.386 203.151 204.078 202.549C203.777 201.941 203.627 201.233 203.627 200.426C203.627 199.62 203.777 198.916 204.078 198.314C204.386 197.706 204.818 197.24 205.376 196.917C205.94 196.587 206.597 196.422 207.345 196.422C208.159 196.422 208.859 196.617 209.446 197.005C210.032 197.387 210.465 197.94 210.744 198.666L209.479 199.161C209.31 198.685 209.042 198.329 208.676 198.094C208.316 197.852 207.873 197.731 207.345 197.731C206.604 197.731 206.028 197.966 205.618 198.435C205.207 198.897 205.002 199.557 205.002 200.415C205.002 201.273 205.207 201.941 205.618 202.417C206.028 202.887 206.604 203.121 207.345 203.121C207.873 203.121 208.32 203 208.687 202.758C209.053 202.509 209.317 202.142 209.479 201.658L210.766 202.142C210.494 202.883 210.062 203.451 209.468 203.847C208.874 204.236 208.166 204.43 207.345 204.43ZM216.215 201.482C216.215 201.644 216.204 201.812 216.182 201.988H212.464C212.493 202.355 212.622 202.645 212.849 202.857C213.076 203.07 213.399 203.176 213.817 203.176C214.345 203.176 214.778 202.982 215.115 202.593L216.028 203.396C215.727 203.726 215.394 203.972 215.027 204.133C214.668 204.295 214.261 204.375 213.806 204.375C213.212 204.375 212.713 204.247 212.31 203.99C211.914 203.734 211.621 203.396 211.43 202.978C211.239 202.553 211.144 202.087 211.144 201.581C211.144 201.083 211.236 200.617 211.419 200.184C211.61 199.752 211.896 199.403 212.277 199.139C212.666 198.868 213.146 198.732 213.718 198.732C214.261 198.732 214.719 198.853 215.093 199.095C215.467 199.337 215.746 199.667 215.929 200.085C216.12 200.503 216.215 200.969 216.215 201.482ZM214.95 200.943C214.943 200.606 214.822 200.338 214.587 200.14C214.352 199.935 214.059 199.832 213.707 199.832C213.333 199.832 213.04 199.942 212.827 200.162C212.622 200.375 212.497 200.635 212.453 200.943H214.95ZM218.52 204.375C218.131 204.375 217.82 204.258 217.585 204.023C217.358 203.789 217.244 203.437 217.244 202.967V196.598H218.564V202.879C218.564 203.107 218.692 203.22 218.949 203.22C219.074 203.22 219.213 203.198 219.367 203.154V204.21C219.074 204.32 218.791 204.375 218.52 204.375ZM221.582 204.375C221.193 204.375 220.881 204.258 220.647 204.023C220.419 203.789 220.306 203.437 220.306 202.967V196.598H221.626V202.879C221.626 203.107 221.754 203.22 222.011 203.22C222.135 203.22 222.275 203.198 222.429 203.154V204.21C222.135 204.32 221.853 204.375 221.582 204.375ZM230.453 202.681H227.45L226.867 204.265H225.371L228.44 196.598H229.474L232.532 204.265H231.036L230.453 202.681ZM229.991 201.416L228.957 198.622L227.923 201.416H229.991ZM234.641 199.887V202.648C234.641 202.861 234.699 203.019 234.817 203.121C234.941 203.224 235.114 203.275 235.334 203.275C235.517 203.275 235.737 203.235 235.994 203.154V204.21C235.664 204.32 235.334 204.375 235.004 204.375C234.512 204.375 234.109 204.243 233.794 203.979C233.478 203.708 233.321 203.297 233.321 202.747V199.887H232.441V198.842H233.321V197.577L234.641 196.598V198.842H235.994V199.887H234.641ZM238.103 204.375C237.714 204.375 237.403 204.258 237.168 204.023C236.941 203.789 236.827 203.437 236.827 202.967V196.598H238.147V202.879C238.147 203.107 238.275 203.22 238.532 203.22C238.657 203.22 238.796 203.198 238.95 203.154V204.21C238.657 204.32 238.374 204.375 238.103 204.375ZM242.012 198.732C242.731 198.732 243.296 198.923 243.706 199.304C244.124 199.678 244.333 200.192 244.333 200.844V204.265H243.123L243.013 203.561C242.852 203.818 242.625 204.02 242.331 204.166C242.045 204.306 241.723 204.375 241.363 204.375C240.989 204.375 240.652 204.302 240.351 204.155C240.058 204.001 239.827 203.789 239.658 203.517C239.49 203.246 239.405 202.942 239.405 202.604C239.405 202.282 239.475 202.003 239.614 201.768C239.754 201.534 239.955 201.358 240.219 201.24C240.571 201.079 241.052 200.998 241.66 200.998H243.013V200.844C243.013 200.551 242.922 200.32 242.738 200.151C242.555 199.975 242.306 199.887 241.99 199.887C241.712 199.887 241.448 199.957 241.198 200.096C240.949 200.236 240.725 200.437 240.527 200.701L239.57 199.898C240.216 199.121 241.03 198.732 242.012 198.732ZM241.572 203.253C241.968 203.253 242.306 203.132 242.584 202.89C242.87 202.641 243.013 202.34 243.013 201.988H241.836C241.411 201.988 241.114 202.051 240.945 202.175C240.799 202.278 240.725 202.428 240.725 202.626C240.725 202.817 240.799 202.971 240.945 203.088C241.099 203.198 241.308 203.253 241.572 203.253ZM247.428 204.375C246.878 204.375 246.394 204.232 245.976 203.946C245.565 203.653 245.29 203.29 245.151 202.857L246.207 202.384C246.42 202.978 246.805 203.275 247.362 203.275C247.648 203.275 247.864 203.209 248.011 203.077C248.165 202.945 248.242 202.799 248.242 202.637C248.242 202.476 248.165 202.355 248.011 202.274C247.857 202.194 247.604 202.102 247.252 201.999C246.885 201.904 246.581 201.805 246.339 201.702C246.097 201.592 245.888 201.427 245.712 201.207C245.536 200.98 245.448 200.683 245.448 200.316C245.448 199.818 245.639 199.429 246.02 199.15C246.409 198.872 246.882 198.732 247.439 198.732C247.901 198.732 248.308 198.835 248.66 199.04C249.012 199.246 249.291 199.535 249.496 199.909L248.473 200.47C248.363 200.265 248.224 200.1 248.055 199.975C247.886 199.843 247.666 199.777 247.395 199.777C247.19 199.777 247.021 199.821 246.889 199.909C246.764 199.997 246.702 200.107 246.702 200.239C246.702 200.386 246.779 200.5 246.933 200.58C247.094 200.661 247.34 200.745 247.67 200.833C248.051 200.943 248.367 201.053 248.616 201.163C248.865 201.273 249.082 201.442 249.265 201.669C249.448 201.897 249.54 202.194 249.54 202.56C249.54 202.964 249.437 203.301 249.232 203.572C249.034 203.844 248.774 204.045 248.451 204.177C248.128 204.309 247.787 204.375 247.428 204.375Z" fill="black" /> <g class="al-2023-active-dots green" id="active dots_15"> <circle id="Ellipse 2765_15" cx="144.022" cy="194.528" r="48.5676" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2767_15" cx="144.022" cy="194.528" r="25.309" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2771_15" cx="144.022" cy="194.528" r="13.0446" fill="white" stroke="#22704F" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot green" id="inactive dot_15" cx="144.022" cy="194.528" r="10.2374" fill="#22704F" stroke="white" stroke-width="3" /> <circle class="overlay-dot green" id="inactive dot_15" cx="144.022" cy="194.528" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="6-CELLxGENE-Annotate" data-milestone="cellxgene-annotate" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_42" d="M435.987 60.75L435.987 146.599" stroke="url(#paint17_linear_42_3042)" stroke-width="1.5" /> <path class="al-2023-svg-text" d="M458.176 125.498C457.428 125.498 456.772 125.337 456.207 125.014C455.65 124.684 455.217 124.219 454.909 123.617C454.609 123.009 454.458 122.301 454.458 121.494C454.458 120.688 454.609 119.984 454.909 119.382C455.217 118.774 455.65 118.308 456.207 117.985C456.772 117.655 457.428 117.49 458.176 117.49C458.99 117.49 459.691 117.685 460.277 118.073C460.864 118.455 461.297 119.008 461.575 119.734L460.31 120.229C460.142 119.753 459.874 119.397 459.507 119.162C459.148 118.92 458.704 118.799 458.176 118.799C457.436 118.799 456.86 119.034 456.449 119.503C456.039 119.965 455.833 120.625 455.833 121.483C455.833 122.341 456.039 123.009 456.449 123.485C456.86 123.955 457.436 124.189 458.176 124.189C458.704 124.189 459.152 124.068 459.518 123.826C459.885 123.577 460.149 123.21 460.31 122.726L461.597 123.21C461.326 123.951 460.893 124.519 460.299 124.915C459.705 125.304 458.998 125.498 458.176 125.498ZM462.807 117.666H467.911V118.931H464.182V120.757H467.647V122.022H464.182V124.068H467.911V125.333H462.807V117.666ZM469.521 117.666H470.896V124.068H474.174V125.333H469.521V117.666ZM475.236 117.666H476.611V124.068H479.889V125.333H475.236V117.666ZM481.875 122.605L480.016 119.91H481.633L482.755 121.703L483.877 119.91H485.494L483.624 122.605L485.494 125.333H483.877L482.755 123.507L481.633 125.333H480.016L481.875 122.605ZM493.127 121.186V125.333H492.148L491.983 124.541C491.755 124.849 491.444 125.088 491.048 125.256C490.659 125.418 490.215 125.498 489.717 125.498C489.005 125.498 488.36 125.333 487.781 125.003C487.209 124.666 486.758 124.193 486.428 123.584C486.098 122.976 485.933 122.275 485.933 121.483C485.933 120.721 486.083 120.039 486.384 119.437C486.692 118.829 487.128 118.352 487.693 118.007C488.265 117.663 488.925 117.49 489.673 117.49C490.465 117.49 491.154 117.685 491.741 118.073C492.335 118.462 492.771 119.016 493.05 119.734L491.785 120.229C491.616 119.76 491.348 119.404 490.982 119.162C490.615 118.92 490.171 118.799 489.651 118.799C488.91 118.799 488.334 119.034 487.924 119.503C487.513 119.973 487.308 120.629 487.308 121.472C487.308 122.338 487.528 123.009 487.968 123.485C488.408 123.955 489.02 124.189 489.805 124.189C490.421 124.189 490.901 124.046 491.246 123.76C491.59 123.467 491.763 123.064 491.763 122.55V122.451H490.047V121.186H493.127ZM494.776 117.666H499.88V118.931H496.151V120.757H499.616V122.022H496.151V124.068H499.88V125.333H494.776V117.666ZM507.507 117.666V125.333H506.077L502.865 120.031V125.333H501.49V117.666H502.909L506.132 122.946V117.666H507.507ZM509.439 117.666H514.543V118.931H510.814V120.757H514.279V122.022H510.814V124.068H514.543V125.333H509.439V117.666ZM459.166 136.749H456.163L455.58 138.333H454.084L457.153 130.666H458.187L461.245 138.333H459.749L459.166 136.749ZM458.704 135.484L457.67 132.69L456.636 135.484H458.704ZM464.999 132.8C465.607 132.8 466.077 132.98 466.407 133.339C466.744 133.691 466.913 134.19 466.913 134.835V138.333H465.593V135.165C465.593 134.835 465.534 134.553 465.417 134.318C465.299 134.076 465.024 133.955 464.592 133.955C464.21 133.955 463.928 134.065 463.745 134.285C463.569 134.498 463.459 134.755 463.415 135.055C463.378 135.349 463.36 135.719 463.36 136.166V138.333H462.04V132.91H463.36V133.537C463.543 133.288 463.774 133.105 464.053 132.987C464.339 132.863 464.654 132.8 464.999 132.8ZM471.294 132.8C471.902 132.8 472.372 132.98 472.702 133.339C473.039 133.691 473.208 134.19 473.208 134.835V138.333H471.888V135.165C471.888 134.835 471.829 134.553 471.712 134.318C471.594 134.076 471.319 133.955 470.887 133.955C470.505 133.955 470.223 134.065 470.04 134.285C469.864 134.498 469.754 134.755 469.71 135.055C469.673 135.349 469.655 135.719 469.655 136.166V138.333H468.335V132.91H469.655V133.537C469.838 133.288 470.069 133.105 470.348 132.987C470.634 132.863 470.949 132.8 471.294 132.8ZM476.863 138.443C476.32 138.443 475.84 138.319 475.422 138.069C475.011 137.813 474.696 137.468 474.476 137.035C474.256 136.603 474.146 136.13 474.146 135.616C474.146 135.103 474.256 134.634 474.476 134.208C474.696 133.776 475.011 133.435 475.422 133.185C475.84 132.929 476.32 132.8 476.863 132.8C477.405 132.8 477.882 132.929 478.293 133.185C478.703 133.435 479.019 133.776 479.239 134.208C479.466 134.634 479.58 135.103 479.58 135.616C479.58 136.13 479.466 136.603 479.239 137.035C479.019 137.468 478.703 137.813 478.293 138.069C477.882 138.319 477.405 138.443 476.863 138.443ZM476.863 137.288C477.332 137.288 477.68 137.131 477.908 136.815C478.142 136.5 478.26 136.1 478.26 135.616C478.26 135.132 478.142 134.736 477.908 134.428C477.68 134.113 477.332 133.955 476.863 133.955C476.393 133.955 476.041 134.113 475.807 134.428C475.579 134.736 475.466 135.132 475.466 135.616C475.466 136.1 475.579 136.5 475.807 136.815C476.041 137.131 476.393 137.288 476.863 137.288ZM482.153 133.955V136.716C482.153 136.929 482.212 137.087 482.329 137.189C482.454 137.292 482.626 137.343 482.846 137.343C483.029 137.343 483.249 137.303 483.506 137.222V138.278C483.176 138.388 482.846 138.443 482.516 138.443C482.025 138.443 481.621 138.311 481.306 138.047C480.991 137.776 480.833 137.365 480.833 136.815V133.955H479.953V132.91H480.833V131.645L482.153 130.666V132.91H483.506V133.955H482.153ZM486.796 132.8C487.515 132.8 488.079 132.991 488.49 133.372C488.908 133.746 489.117 134.26 489.117 134.912V138.333H487.907L487.797 137.629C487.636 137.886 487.408 138.088 487.115 138.234C486.829 138.374 486.506 138.443 486.147 138.443C485.773 138.443 485.436 138.37 485.135 138.223C484.842 138.069 484.611 137.857 484.442 137.585C484.273 137.314 484.189 137.01 484.189 136.672C484.189 136.35 484.259 136.071 484.398 135.836C484.537 135.602 484.739 135.426 485.003 135.308C485.355 135.147 485.835 135.066 486.444 135.066H487.797V134.912C487.797 134.619 487.705 134.388 487.522 134.219C487.339 134.043 487.089 133.955 486.774 133.955C486.495 133.955 486.231 134.025 485.982 134.164C485.733 134.304 485.509 134.505 485.311 134.769L484.354 133.966C484.999 133.189 485.813 132.8 486.796 132.8ZM486.356 137.321C486.752 137.321 487.089 137.2 487.368 136.958C487.654 136.709 487.797 136.408 487.797 136.056H486.62C486.195 136.056 485.898 136.119 485.729 136.243C485.582 136.346 485.509 136.496 485.509 136.694C485.509 136.885 485.582 137.039 485.729 137.156C485.883 137.266 486.092 137.321 486.356 137.321ZM492.014 133.955V136.716C492.014 136.929 492.073 137.087 492.19 137.189C492.315 137.292 492.487 137.343 492.707 137.343C492.891 137.343 493.111 137.303 493.367 137.222V138.278C493.037 138.388 492.707 138.443 492.377 138.443C491.886 138.443 491.483 138.311 491.167 138.047C490.852 137.776 490.694 137.365 490.694 136.815V133.955H489.814V132.91H490.694V131.645L492.014 130.666V132.91H493.367V133.955H492.014ZM499.09 135.55C499.09 135.712 499.079 135.88 499.057 136.056H495.339C495.369 136.423 495.497 136.713 495.724 136.925C495.952 137.138 496.274 137.244 496.692 137.244C497.22 137.244 497.653 137.05 497.99 136.661L498.903 137.464C498.603 137.794 498.269 138.04 497.902 138.201C497.543 138.363 497.136 138.443 496.681 138.443C496.087 138.443 495.589 138.315 495.185 138.058C494.789 137.802 494.496 137.464 494.305 137.046C494.115 136.621 494.019 136.155 494.019 135.649C494.019 135.151 494.111 134.685 494.294 134.252C494.485 133.82 494.771 133.471 495.152 133.207C495.541 132.936 496.021 132.8 496.593 132.8C497.136 132.8 497.594 132.921 497.968 133.163C498.342 133.405 498.621 133.735 498.804 134.153C498.995 134.571 499.09 135.037 499.09 135.55ZM497.825 135.011C497.818 134.674 497.697 134.406 497.462 134.208C497.228 134.003 496.934 133.9 496.582 133.9C496.208 133.9 495.915 134.01 495.702 134.23C495.497 134.443 495.372 134.703 495.328 135.011H497.825Z" fill="black" /> <g class="al-2023-active-dots turqiose" id="active dots_16"> <circle id="Ellipse 2765_16" cx="435.987" cy="146.599" r="48.5676" fill="#74FFFE" fill-opacity="0.1" /> <circle id="Ellipse 2767_16" cx="435.987" cy="146.599" r="25.309" fill="#74FFFE" fill-opacity="0.4" /> <circle id="Ellipse 2771_16" cx="435.987" cy="146.599" r="13.0446" fill="white" stroke="#73DAD9" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot turqiose" id="inactive dot_16" cx="435.987" cy="146.599" r="10.2374" fill="#73DAD9" stroke="white" stroke-width="3" /> <circle class="overlay-dot turqiose" id="inactive dot_16" cx="435.987" cy="146.599" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="5-Collaborative-Computational-Tools-for-a-Human-Cell-Atlas" data-milestone="collaborative-computational-tools-for-a-human-cell-atlas" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_43" d="M240.389 102.329L197.51 102.329C194.505 102.329 191.516 102.766 188.637 103.626L48.8447 145.386" stroke="#22704F" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M31.646 88.9477C30.898 88.9477 30.2417 88.7864 29.677 88.4637C29.1197 88.1337 28.687 87.668 28.379 87.0667C28.0783 86.458 27.928 85.7504 27.928 84.9437C27.928 84.137 28.0783 83.433 28.379 82.8317C28.687 82.223 29.1197 81.7574 29.677 81.4347C30.2417 81.1047 30.898 80.9397 31.646 80.9397C32.46 80.9397 33.1603 81.134 33.747 81.5227C34.3337 81.904 34.7663 82.4577 35.045 83.1837L33.78 83.6787C33.6113 83.202 33.3437 82.8464 32.977 82.6117C32.6177 82.3697 32.174 82.2487 31.646 82.2487C30.9053 82.2487 30.3297 82.4834 29.919 82.9527C29.5083 83.4147 29.303 84.0747 29.303 84.9327C29.303 85.7907 29.5083 86.458 29.919 86.9347C30.3297 87.404 30.9053 87.6387 31.646 87.6387C32.174 87.6387 32.6213 87.5177 32.988 87.2757C33.3547 87.0264 33.6187 86.6597 33.78 86.1757L35.067 86.6597C34.7957 87.4004 34.363 87.9687 33.769 88.3647C33.175 88.7534 32.4673 88.9477 31.646 88.9477ZM38.1292 88.8927C37.5866 88.8927 37.1062 88.768 36.6882 88.5187C36.2776 88.262 35.9622 87.9174 35.7422 87.4847C35.5222 87.052 35.4122 86.579 35.4122 86.0657C35.4122 85.5524 35.5222 85.083 35.7422 84.6577C35.9622 84.225 36.2776 83.884 36.6882 83.6347C37.1062 83.378 37.5866 83.2497 38.1292 83.2497C38.6719 83.2497 39.1486 83.378 39.5592 83.6347C39.9699 83.884 40.2852 84.225 40.5052 84.6577C40.7326 85.083 40.8462 85.5524 40.8462 86.0657C40.8462 86.579 40.7326 87.052 40.5052 87.4847C40.2852 87.9174 39.9699 88.262 39.5592 88.5187C39.1486 88.768 38.6719 88.8927 38.1292 88.8927ZM38.1292 87.7377C38.5986 87.7377 38.9469 87.58 39.1742 87.2647C39.4089 86.9494 39.5262 86.5497 39.5262 86.0657C39.5262 85.5817 39.4089 85.1857 39.1742 84.8777C38.9469 84.5624 38.5986 84.4047 38.1292 84.4047C37.6599 84.4047 37.3079 84.5624 37.0732 84.8777C36.8459 85.1857 36.7322 85.5817 36.7322 86.0657C36.7322 86.5497 36.8459 86.9494 37.0732 87.2647C37.3079 87.58 37.6599 87.7377 38.1292 87.7377ZM43.1221 88.8927C42.7334 88.8927 42.4218 88.7754 42.1871 88.5407C41.9598 88.306 41.8461 87.954 41.8461 87.4847V81.1157H43.1661V87.3967C43.1661 87.624 43.2944 87.7377 43.5511 87.7377C43.6758 87.7377 43.8151 87.7157 43.9691 87.6717V88.7277C43.6758 88.8377 43.3934 88.8927 43.1221 88.8927ZM46.1836 88.8927C45.795 88.8927 45.4833 88.7754 45.2486 88.5407C45.0213 88.306 44.9076 87.954 44.9076 87.4847V81.1157H46.2276V87.3967C46.2276 87.624 46.356 87.7377 46.6126 87.7377C46.7373 87.7377 46.8766 87.7157 47.0306 87.6717V88.7277C46.7373 88.8377 46.455 88.8927 46.1836 88.8927ZM50.0929 83.2497C50.8116 83.2497 51.3763 83.4404 51.7869 83.8217C52.2049 84.1957 52.4139 84.709 52.4139 85.3617V88.7827H51.2039L51.0939 88.0787C50.9326 88.3354 50.7053 88.537 50.4119 88.6837C50.1259 88.823 49.8033 88.8927 49.4439 88.8927C49.0699 88.8927 48.7326 88.8194 48.4319 88.6727C48.1386 88.5187 47.9076 88.306 47.7389 88.0347C47.5703 87.7634 47.4859 87.459 47.4859 87.1217C47.4859 86.799 47.5556 86.5204 47.6949 86.2857C47.8343 86.051 48.0359 85.875 48.2999 85.7577C48.6519 85.5964 49.1323 85.5157 49.7409 85.5157H51.0939V85.3617C51.0939 85.0684 51.0023 84.8374 50.8189 84.6687C50.6356 84.4927 50.3863 84.4047 50.0709 84.4047C49.7923 84.4047 49.5283 84.4744 49.2789 84.6137C49.0296 84.753 48.8059 84.9547 48.6079 85.2187L47.6509 84.4157C48.2963 83.6384 49.1103 83.2497 50.0929 83.2497ZM49.6529 87.7707C50.0489 87.7707 50.3863 87.6497 50.6649 87.4077C50.9509 87.1584 51.0939 86.8577 51.0939 86.5057H49.9169C49.4916 86.5057 49.1946 86.568 49.0259 86.6927C48.8793 86.7954 48.8059 86.9457 48.8059 87.1437C48.8059 87.3344 48.8793 87.4884 49.0259 87.6057C49.1799 87.7157 49.3889 87.7707 49.6529 87.7707ZM56.6964 83.2497C57.1438 83.2497 57.5398 83.3634 57.8844 83.5907C58.2291 83.8107 58.4968 84.1334 58.6874 84.5587C58.8854 84.984 58.9844 85.4864 58.9844 86.0657C58.9844 86.9017 58.7828 87.5837 58.3794 88.1117C57.9761 88.6324 57.4151 88.8927 56.6964 88.8927C56.3884 88.8927 56.0951 88.8414 55.8164 88.7387C55.5378 88.6287 55.3104 88.4637 55.1344 88.2437V88.7827H53.8144V81.1157H55.1344V83.9097C55.3031 83.7044 55.5268 83.543 55.8054 83.4257C56.0914 83.3084 56.3884 83.2497 56.6964 83.2497ZM56.3774 87.6717C56.8101 87.6717 57.1328 87.536 57.3454 87.2647C57.5581 86.986 57.6644 86.59 57.6644 86.0767C57.6644 85.556 57.5544 85.1564 57.3344 84.8777C57.1218 84.5917 56.7991 84.4487 56.3664 84.4487C55.9191 84.4487 55.5818 84.599 55.3544 84.8997C55.1271 85.2004 55.0134 85.5927 55.0134 86.0767C55.0134 86.5534 55.1271 86.9384 55.3544 87.2317C55.5818 87.525 55.9228 87.6717 56.3774 87.6717ZM62.3421 88.8927C61.7994 88.8927 61.3191 88.768 60.9011 88.5187C60.4904 88.262 60.1751 87.9174 59.9551 87.4847C59.7351 87.052 59.6251 86.579 59.6251 86.0657C59.6251 85.5524 59.7351 85.083 59.9551 84.6577C60.1751 84.225 60.4904 83.884 60.9011 83.6347C61.3191 83.378 61.7994 83.2497 62.3421 83.2497C62.8848 83.2497 63.3614 83.378 63.7721 83.6347C64.1828 83.884 64.4981 84.225 64.7181 84.6577C64.9454 85.083 65.0591 85.5524 65.0591 86.0657C65.0591 86.579 64.9454 87.052 64.7181 87.4847C64.4981 87.9174 64.1828 88.262 63.7721 88.5187C63.3614 88.768 62.8848 88.8927 62.3421 88.8927ZM62.3421 87.7377C62.8114 87.7377 63.1598 87.58 63.3871 87.2647C63.6218 86.9494 63.7391 86.5497 63.7391 86.0657C63.7391 85.5817 63.6218 85.1857 63.3871 84.8777C63.1598 84.5624 62.8114 84.4047 62.3421 84.4047C61.8728 84.4047 61.5208 84.5624 61.2861 84.8777C61.0588 85.1857 60.9451 85.5817 60.9451 86.0657C60.9451 86.5497 61.0588 86.9494 61.2861 87.2647C61.5208 87.58 61.8728 87.7377 62.3421 87.7377ZM68.897 83.2497C69.2563 83.2497 69.601 83.3524 69.931 83.5577L69.293 84.7237C69.1023 84.599 68.8823 84.5367 68.633 84.5367C67.8337 84.5367 67.434 85.0427 67.434 86.0547V88.7827H66.114V83.3597H67.445V84.2837C67.555 83.961 67.742 83.708 68.006 83.5247C68.2773 83.3414 68.5743 83.2497 68.897 83.2497ZM72.7375 83.2497C73.4561 83.2497 74.0208 83.4404 74.4315 83.8217C74.8495 84.1957 75.0585 84.709 75.0585 85.3617V88.7827H73.8485L73.7385 88.0787C73.5771 88.3354 73.3498 88.537 73.0565 88.6837C72.7705 88.823 72.4478 88.8927 72.0885 88.8927C71.7145 88.8927 71.3771 88.8194 71.0765 88.6727C70.7831 88.5187 70.5521 88.306 70.3835 88.0347C70.2148 87.7634 70.1305 87.459 70.1305 87.1217C70.1305 86.799 70.2001 86.5204 70.3395 86.2857C70.4788 86.051 70.6805 85.875 70.9445 85.7577C71.2965 85.5964 71.7768 85.5157 72.3855 85.5157H73.7385V85.3617C73.7385 85.0684 73.6468 84.8374 73.4635 84.6687C73.2801 84.4927 73.0308 84.4047 72.7155 84.4047C72.4368 84.4047 72.1728 84.4744 71.9235 84.6137C71.6741 84.753 71.4505 84.9547 71.2525 85.2187L70.2955 84.4157C70.9408 83.6384 71.7548 83.2497 72.7375 83.2497ZM72.2975 87.7707C72.6935 87.7707 73.0308 87.6497 73.3095 87.4077C73.5955 87.1584 73.7385 86.8577 73.7385 86.5057H72.5615C72.1361 86.5057 71.8391 86.568 71.6705 86.6927C71.5238 86.7954 71.4505 86.9457 71.4505 87.1437C71.4505 87.3344 71.5238 87.4884 71.6705 87.6057C71.8245 87.7157 72.0335 87.7707 72.2975 87.7707ZM77.9558 84.4047V87.1657C77.9558 87.3784 78.0144 87.536 78.1318 87.6387C78.2564 87.7414 78.4288 87.7927 78.6488 87.7927C78.8321 87.7927 79.0521 87.7524 79.3088 87.6717V88.7277C78.9788 88.8377 78.6488 88.8927 78.3188 88.8927C77.8274 88.8927 77.4241 88.7607 77.1088 88.4967C76.7934 88.2254 76.6358 87.8147 76.6358 87.2647V84.4047H75.7558V83.3597H76.6358V82.0947L77.9558 81.1157V83.3597H79.3088V84.4047H77.9558ZM80.4656 83.3597H81.7856V88.7827H80.4656V83.3597ZM80.4326 81.1157H81.8186V82.3367H80.4326V81.1157ZM82.498 83.3597H83.939L85.248 87.0667L86.579 83.3597H88.009L85.798 88.7827H84.709L82.498 83.3597ZM93.1852 85.9997C93.1852 86.161 93.1742 86.3297 93.1522 86.5057H89.4342C89.4635 86.8724 89.5918 87.162 89.8192 87.3747C90.0465 87.5874 90.3692 87.6937 90.7872 87.6937C91.3152 87.6937 91.7478 87.4994 92.0852 87.1107L92.9982 87.9137C92.6975 88.2437 92.3638 88.4894 91.9972 88.6507C91.6378 88.812 91.2308 88.8927 90.7762 88.8927C90.1822 88.8927 89.6835 88.7644 89.2802 88.5077C88.8842 88.251 88.5908 87.9137 88.4002 87.4957C88.2095 87.0704 88.1142 86.6047 88.1142 86.0987C88.1142 85.6 88.2058 85.1344 88.3892 84.7017C88.5798 84.269 88.8658 83.9207 89.2472 83.6567C89.6358 83.3854 90.1162 83.2497 90.6882 83.2497C91.2308 83.2497 91.6892 83.3707 92.0632 83.6127C92.4372 83.8547 92.7158 84.1847 92.8992 84.6027C93.0898 85.0207 93.1852 85.4864 93.1852 85.9997ZM91.9202 85.4607C91.9128 85.1234 91.7918 84.8557 91.5572 84.6577C91.3225 84.4524 91.0292 84.3497 90.6772 84.3497C90.3032 84.3497 90.0098 84.4597 89.7972 84.6797C89.5918 84.8924 89.4672 85.1527 89.4232 85.4607H91.9202ZM31.646 100.948C30.898 100.948 30.2417 100.786 29.677 100.464C29.1197 100.134 28.687 99.668 28.379 99.0667C28.0783 98.458 27.928 97.7504 27.928 96.9437C27.928 96.137 28.0783 95.433 28.379 94.8317C28.687 94.223 29.1197 93.7574 29.677 93.4347C30.2417 93.1047 30.898 92.9397 31.646 92.9397C32.46 92.9397 33.1603 93.134 33.747 93.5227C34.3337 93.904 34.7663 94.4577 35.045 95.1837L33.78 95.6787C33.6113 95.202 33.3437 94.8464 32.977 94.6117C32.6177 94.3697 32.174 94.2487 31.646 94.2487C30.9053 94.2487 30.3297 94.4834 29.919 94.9527C29.5083 95.4147 29.303 96.0747 29.303 96.9327C29.303 97.7907 29.5083 98.458 29.919 98.9347C30.3297 99.404 30.9053 99.6387 31.646 99.6387C32.174 99.6387 32.6213 99.5177 32.988 99.2757C33.3547 99.0264 33.6187 98.6597 33.78 98.1757L35.067 98.6597C34.7957 99.4004 34.363 99.9687 33.769 100.365C33.175 100.753 32.4673 100.948 31.646 100.948ZM38.1292 100.893C37.5866 100.893 37.1062 100.768 36.6882 100.519C36.2776 100.262 35.9622 99.9174 35.7422 99.4847C35.5222 99.052 35.4122 98.579 35.4122 98.0657C35.4122 97.5524 35.5222 97.083 35.7422 96.6577C35.9622 96.225 36.2776 95.884 36.6882 95.6347C37.1062 95.378 37.5866 95.2497 38.1292 95.2497C38.6719 95.2497 39.1486 95.378 39.5592 95.6347C39.9699 95.884 40.2852 96.225 40.5052 96.6577C40.7326 97.083 40.8462 97.5524 40.8462 98.0657C40.8462 98.579 40.7326 99.052 40.5052 99.4847C40.2852 99.9174 39.9699 100.262 39.5592 100.519C39.1486 100.768 38.6719 100.893 38.1292 100.893ZM38.1292 99.7377C38.5986 99.7377 38.9469 99.58 39.1742 99.2647C39.4089 98.9494 39.5262 98.5497 39.5262 98.0657C39.5262 97.5817 39.4089 97.1857 39.1742 96.8777C38.9469 96.5624 38.5986 96.4047 38.1292 96.4047C37.6599 96.4047 37.3079 96.5624 37.0732 96.8777C36.8459 97.1857 36.7322 97.5817 36.7322 98.0657C36.7322 98.5497 36.8459 98.9494 37.0732 99.2647C37.3079 99.58 37.6599 99.7377 38.1292 99.7377ZM47.9621 95.2497C48.5781 95.2497 49.0474 95.4514 49.3701 95.8547C49.6928 96.2507 49.8541 96.742 49.8541 97.3287V100.783H48.5341V97.7247C48.5341 96.8447 48.2261 96.4047 47.6101 96.4047C47.2654 96.4047 47.0161 96.5147 46.8621 96.7347C46.7081 96.9474 46.6164 97.2004 46.5871 97.4937C46.5578 97.7797 46.5431 98.1867 46.5431 98.7147V100.783H45.2231V97.7247C45.2231 96.8447 44.9188 96.4047 44.3101 96.4047C43.9654 96.4047 43.7161 96.5147 43.5621 96.7347C43.4081 96.9474 43.3128 97.204 43.2761 97.5047C43.2468 97.798 43.2321 98.2014 43.2321 98.7147V100.783H41.9121L41.9011 95.3597H43.1771V96.0417C43.4851 95.5137 43.9691 95.2497 44.6291 95.2497C44.9664 95.2497 45.2744 95.3304 45.5531 95.4917C45.8391 95.653 46.0591 95.928 46.2131 96.3167C46.4111 95.9354 46.6568 95.664 46.9501 95.5027C47.2434 95.334 47.5808 95.2497 47.9621 95.2497ZM54.1505 95.2497C54.8692 95.2497 55.4302 95.5137 55.8335 96.0417C56.2369 96.5624 56.4385 97.2407 56.4385 98.0767C56.4385 98.656 56.3395 99.1584 56.1415 99.5837C55.9509 100.009 55.6832 100.335 55.3385 100.563C54.9939 100.783 54.5979 100.893 54.1505 100.893C53.8425 100.893 53.5455 100.834 53.2595 100.717C52.9809 100.599 52.7572 100.438 52.5885 100.233V103.027H51.2685V95.3597H52.5885V95.8987C52.7645 95.6787 52.9919 95.5174 53.2705 95.4147C53.5492 95.3047 53.8425 95.2497 54.1505 95.2497ZM53.8205 99.7377C54.2532 99.7377 54.5759 99.5947 54.7885 99.3087C55.0085 99.0154 55.1185 98.601 55.1185 98.0657C55.1185 96.9584 54.6895 96.4047 53.8315 96.4047C53.3695 96.4047 53.0249 96.555 52.7975 96.8557C52.5775 97.1564 52.4675 97.5597 52.4675 98.0657C52.4675 98.5644 52.5775 98.9677 52.7975 99.2757C53.0249 99.5837 53.3659 99.7377 53.8205 99.7377ZM62.2827 95.3597V100.783H60.9627V100.156C60.7794 100.405 60.5447 100.592 60.2587 100.717C59.9801 100.834 59.6757 100.893 59.3457 100.893C58.7004 100.893 58.2164 100.691 57.8937 100.288C57.5711 99.8844 57.4097 99.371 57.4097 98.7477V95.3597H58.7297V98.4177C58.7297 98.7624 58.7884 99.0704 58.9057 99.3417C59.0231 99.6057 59.2981 99.7377 59.7307 99.7377C60.1121 99.7377 60.3907 99.6204 60.5667 99.3857C60.7501 99.151 60.8601 98.8797 60.8967 98.5717C60.9407 98.2637 60.9627 97.8787 60.9627 97.4167V95.3597H62.2827ZM65.3659 96.4047V99.1657C65.3659 99.3784 65.4246 99.536 65.5419 99.6387C65.6666 99.7414 65.8389 99.7927 66.0589 99.7927C66.2422 99.7927 66.4622 99.7524 66.7189 99.6717V100.728C66.3889 100.838 66.0589 100.893 65.7289 100.893C65.2376 100.893 64.8342 100.761 64.5189 100.497C64.2036 100.225 64.0459 99.8147 64.0459 99.2647V96.4047H63.1659V95.3597H64.0459V94.0947L65.3659 93.1157V95.3597H66.7189V96.4047H65.3659ZM70.0089 95.2497C70.7276 95.2497 71.2923 95.4404 71.7029 95.8217C72.1209 96.1957 72.3299 96.709 72.3299 97.3617V100.783H71.1199L71.0099 100.079C70.8486 100.335 70.6213 100.537 70.3279 100.684C70.0419 100.823 69.7193 100.893 69.3599 100.893C68.9859 100.893 68.6486 100.819 68.3479 100.673C68.0546 100.519 67.8236 100.306 67.6549 100.035C67.4863 99.7634 67.4019 99.459 67.4019 99.1217C67.4019 98.799 67.4716 98.5204 67.6109 98.2857C67.7503 98.051 67.9519 97.875 68.2159 97.7577C68.5679 97.5964 69.0483 97.5157 69.6569 97.5157H71.0099V97.3617C71.0099 97.0684 70.9183 96.8374 70.7349 96.6687C70.5516 96.4927 70.3023 96.4047 69.9869 96.4047C69.7083 96.4047 69.4443 96.4744 69.1949 96.6137C68.9456 96.753 68.7219 96.9547 68.5239 97.2187L67.5669 96.4157C68.2123 95.6384 69.0263 95.2497 70.0089 95.2497ZM69.5689 99.7707C69.9649 99.7707 70.3023 99.6497 70.5809 99.4077C70.8669 99.1584 71.0099 98.8577 71.0099 98.5057H69.8329C69.4076 98.5057 69.1106 98.568 68.9419 98.6927C68.7953 98.7954 68.7219 98.9457 68.7219 99.1437C68.7219 99.3344 68.7953 99.4884 68.9419 99.6057C69.0959 99.7157 69.3049 99.7707 69.5689 99.7707ZM75.2272 96.4047V99.1657C75.2272 99.3784 75.2859 99.536 75.4032 99.6387C75.5279 99.7414 75.7002 99.7927 75.9202 99.7927C76.1036 99.7927 76.3236 99.7524 76.5802 99.6717V100.728C76.2502 100.838 75.9202 100.893 75.5902 100.893C75.0989 100.893 74.6956 100.761 74.3802 100.497C74.0649 100.225 73.9072 99.8147 73.9072 99.2647V96.4047H73.0272V95.3597H73.9072V94.0947L75.2272 93.1157V95.3597H76.5802V96.4047H75.2272ZM77.737 95.3597H79.057V100.783H77.737V95.3597ZM77.704 93.1157H79.09V94.3367H77.704V93.1157ZM82.8275 100.893C82.2848 100.893 81.8045 100.768 81.3865 100.519C80.9758 100.262 80.6605 99.9174 80.4405 99.4847C80.2205 99.052 80.1105 98.579 80.1105 98.0657C80.1105 97.5524 80.2205 97.083 80.4405 96.6577C80.6605 96.225 80.9758 95.884 81.3865 95.6347C81.8045 95.378 82.2848 95.2497 82.8275 95.2497C83.3701 95.2497 83.8468 95.378 84.2575 95.6347C84.6681 95.884 84.9835 96.225 85.2035 96.6577C85.4308 97.083 85.5445 97.5524 85.5445 98.0657C85.5445 98.579 85.4308 99.052 85.2035 99.4847C84.9835 99.9174 84.6681 100.262 84.2575 100.519C83.8468 100.768 83.3701 100.893 82.8275 100.893ZM82.8275 99.7377C83.2968 99.7377 83.6451 99.58 83.8725 99.2647C84.1071 98.9494 84.2245 98.5497 84.2245 98.0657C84.2245 97.5817 84.1071 97.1857 83.8725 96.8777C83.6451 96.5624 83.2968 96.4047 82.8275 96.4047C82.3581 96.4047 82.0061 96.5624 81.7715 96.8777C81.5441 97.1857 81.4305 97.5817 81.4305 98.0657C81.4305 98.5497 81.5441 98.9494 81.7715 99.2647C82.0061 99.58 82.3581 99.7377 82.8275 99.7377ZM89.5583 95.2497C90.167 95.2497 90.6363 95.4294 90.9663 95.7887C91.3037 96.1407 91.4723 96.6394 91.4723 97.2847V100.783H90.1523V97.6147C90.1523 97.2847 90.0937 97.0024 89.9763 96.7677C89.859 96.5257 89.584 96.4047 89.1513 96.4047C88.77 96.4047 88.4877 96.5147 88.3043 96.7347C88.1283 96.9474 88.0183 97.204 87.9743 97.5047C87.9377 97.798 87.9193 98.1684 87.9193 98.6157V100.783H86.5993V95.3597H87.9193V95.9867C88.1027 95.7374 88.3337 95.554 88.6123 95.4367C88.8983 95.312 89.2137 95.2497 89.5583 95.2497ZM94.9953 95.2497C95.7139 95.2497 96.2786 95.4404 96.6893 95.8217C97.1073 96.1957 97.3163 96.709 97.3163 97.3617V100.783H96.1063L95.9963 100.079C95.8349 100.335 95.6076 100.537 95.3143 100.684C95.0283 100.823 94.7056 100.893 94.3463 100.893C93.9723 100.893 93.6349 100.819 93.3343 100.673C93.0409 100.519 92.8099 100.306 92.6413 100.035C92.4726 99.7634 92.3883 99.459 92.3883 99.1217C92.3883 98.799 92.4579 98.5204 92.5973 98.2857C92.7366 98.051 92.9383 97.875 93.2023 97.7577C93.5543 97.5964 94.0346 97.5157 94.6433 97.5157H95.9963V97.3617C95.9963 97.0684 95.9046 96.8374 95.7213 96.6687C95.5379 96.4927 95.2886 96.4047 94.9733 96.4047C94.6946 96.4047 94.4306 96.4744 94.1813 96.6137C93.9319 96.753 93.7083 96.9547 93.5103 97.2187L92.5533 96.4157C93.1986 95.6384 94.0126 95.2497 94.9953 95.2497ZM94.5553 99.7707C94.9513 99.7707 95.2886 99.6497 95.5673 99.4077C95.8533 99.1584 95.9963 98.8577 95.9963 98.5057H94.8193C94.3939 98.5057 94.0969 98.568 93.9283 98.6927C93.7816 98.7954 93.7083 98.9457 93.7083 99.1437C93.7083 99.3344 93.7816 99.4884 93.9283 99.6057C94.0823 99.7157 94.2913 99.7707 94.5553 99.7707ZM99.9268 100.893C99.5381 100.893 99.2265 100.775 98.9918 100.541C98.7645 100.306 98.6508 99.954 98.6508 99.4847V93.1157H99.9708V99.3967C99.9708 99.624 100.099 99.7377 100.356 99.7377C100.48 99.7377 100.62 99.7157 100.774 99.6717V100.728C100.48 100.838 100.198 100.893 99.9268 100.893ZM29.996 106.381H27.598V105.116H33.78V106.381H31.382V112.783H29.996V106.381ZM35.8197 112.893C35.277 112.893 34.7967 112.768 34.3787 112.519C33.968 112.262 33.6527 111.917 33.4327 111.485C33.2127 111.052 33.1027 110.579 33.1027 110.066C33.1027 109.552 33.2127 109.083 33.4327 108.658C33.6527 108.225 33.968 107.884 34.3787 107.635C34.7967 107.378 35.277 107.25 35.8197 107.25C36.3623 107.25 36.839 107.378 37.2497 107.635C37.6603 107.884 37.9757 108.225 38.1957 108.658C38.423 109.083 38.5367 109.552 38.5367 110.066C38.5367 110.579 38.423 111.052 38.1957 111.485C37.9757 111.917 37.6603 112.262 37.2497 112.519C36.839 112.768 36.3623 112.893 35.8197 112.893ZM35.8197 111.738C36.289 111.738 36.6373 111.58 36.8647 111.265C37.0993 110.949 37.2167 110.55 37.2167 110.066C37.2167 109.582 37.0993 109.186 36.8647 108.878C36.6373 108.562 36.289 108.405 35.8197 108.405C35.3503 108.405 34.9983 108.562 34.7637 108.878C34.5363 109.186 34.4227 109.582 34.4227 110.066C34.4227 110.55 34.5363 110.949 34.7637 111.265C34.9983 111.58 35.3503 111.738 35.8197 111.738ZM41.8245 112.893C41.2819 112.893 40.8015 112.768 40.3835 112.519C39.9729 112.262 39.6575 111.917 39.4375 111.485C39.2175 111.052 39.1075 110.579 39.1075 110.066C39.1075 109.552 39.2175 109.083 39.4375 108.658C39.6575 108.225 39.9729 107.884 40.3835 107.635C40.8015 107.378 41.2819 107.25 41.8245 107.25C42.3672 107.25 42.8439 107.378 43.2545 107.635C43.6652 107.884 43.9805 108.225 44.2005 108.658C44.4279 109.083 44.5415 109.552 44.5415 110.066C44.5415 110.579 44.4279 111.052 44.2005 111.485C43.9805 111.917 43.6652 112.262 43.2545 112.519C42.8439 112.768 42.3672 112.893 41.8245 112.893ZM41.8245 111.738C42.2939 111.738 42.6422 111.58 42.8695 111.265C43.1042 110.949 43.2215 110.55 43.2215 110.066C43.2215 109.582 43.1042 109.186 42.8695 108.878C42.6422 108.562 42.2939 108.405 41.8245 108.405C41.3552 108.405 41.0032 108.562 40.7685 108.878C40.5412 109.186 40.4275 109.582 40.4275 110.066C40.4275 110.55 40.5412 110.949 40.7685 111.265C41.0032 111.58 41.3552 111.738 41.8245 111.738ZM46.8174 112.893C46.4287 112.893 46.1171 112.775 45.8824 112.541C45.6551 112.306 45.5414 111.954 45.5414 111.485V105.116H46.8614V111.397C46.8614 111.624 46.9897 111.738 47.2464 111.738C47.3711 111.738 47.5104 111.716 47.6644 111.672V112.728C47.3711 112.838 47.0887 112.893 46.8174 112.893ZM50.3629 112.893C49.8129 112.893 49.3289 112.75 48.9109 112.464C48.5003 112.17 48.2253 111.807 48.0859 111.375L49.1419 110.902C49.3546 111.496 49.7396 111.793 50.2969 111.793C50.5829 111.793 50.7993 111.727 50.9459 111.595C51.0999 111.463 51.1769 111.316 51.1769 111.155C51.1769 110.993 51.0999 110.872 50.9459 110.792C50.7919 110.711 50.5389 110.619 50.1869 110.517C49.8203 110.421 49.5159 110.322 49.2739 110.22C49.0319 110.11 48.8229 109.945 48.6469 109.725C48.4709 109.497 48.3829 109.2 48.3829 108.834C48.3829 108.335 48.5736 107.946 48.9549 107.668C49.3436 107.389 49.8166 107.25 50.3739 107.25C50.8359 107.25 51.2429 107.352 51.5949 107.558C51.9469 107.763 52.2256 108.053 52.4309 108.427L51.4079 108.988C51.2979 108.782 51.1586 108.617 50.9899 108.493C50.8213 108.361 50.6013 108.295 50.3299 108.295C50.1246 108.295 49.9559 108.339 49.8239 108.427C49.6993 108.515 49.6369 108.625 49.6369 108.757C49.6369 108.903 49.7139 109.017 49.8679 109.098C50.0293 109.178 50.2749 109.263 50.6049 109.351C50.9863 109.461 51.3016 109.571 51.5509 109.681C51.8003 109.791 52.0166 109.959 52.1999 110.187C52.3833 110.414 52.4749 110.711 52.4749 111.078C52.4749 111.481 52.3723 111.818 52.1669 112.09C51.9689 112.361 51.7086 112.563 51.3859 112.695C51.0633 112.827 50.7223 112.893 50.3629 112.893ZM56.5824 108.405H55.5484V107.36H56.5934V106.744C56.5934 105.585 57.1397 105.006 58.2324 105.006C58.5991 105.006 58.9401 105.079 59.2554 105.226L58.8264 106.238C58.6871 106.15 58.5367 106.106 58.3754 106.106C58.1701 106.106 58.0381 106.168 57.9794 106.293C57.9281 106.417 57.9024 106.564 57.9024 106.733V107.36H59.1674V108.405H57.9024V112.783H56.5824V108.405ZM62.0198 112.893C61.4772 112.893 60.9968 112.768 60.5788 112.519C60.1682 112.262 59.8528 111.917 59.6328 111.485C59.4128 111.052 59.3028 110.579 59.3028 110.066C59.3028 109.552 59.4128 109.083 59.6328 108.658C59.8528 108.225 60.1682 107.884 60.5788 107.635C60.9968 107.378 61.4772 107.25 62.0198 107.25C62.5625 107.25 63.0392 107.378 63.4498 107.635C63.8605 107.884 64.1758 108.225 64.3958 108.658C64.6232 109.083 64.7368 109.552 64.7368 110.066C64.7368 110.579 64.6232 111.052 64.3958 111.485C64.1758 111.917 63.8605 112.262 63.4498 112.519C63.0392 112.768 62.5625 112.893 62.0198 112.893ZM62.0198 111.738C62.4892 111.738 62.8375 111.58 63.0648 111.265C63.2995 110.949 63.4168 110.55 63.4168 110.066C63.4168 109.582 63.2995 109.186 63.0648 108.878C62.8375 108.562 62.4892 108.405 62.0198 108.405C61.5505 108.405 61.1985 108.562 60.9638 108.878C60.7365 109.186 60.6228 109.582 60.6228 110.066C60.6228 110.55 60.7365 110.949 60.9638 111.265C61.1985 111.58 61.5505 111.738 62.0198 111.738ZM68.5747 107.25C68.9341 107.25 69.2787 107.352 69.6087 107.558L68.9707 108.724C68.7801 108.599 68.5601 108.537 68.3107 108.537C67.5114 108.537 67.1117 109.043 67.1117 110.055V112.783H65.7917V107.36H67.1227V108.284C67.2327 107.961 67.4197 107.708 67.6837 107.525C67.9551 107.341 68.2521 107.25 68.5747 107.25ZM75.0255 107.25C75.7442 107.25 76.3089 107.44 76.7195 107.822C77.1375 108.196 77.3465 108.709 77.3465 109.362V112.783H76.1365L76.0265 112.079C75.8652 112.335 75.6379 112.537 75.3445 112.684C75.0585 112.823 74.7359 112.893 74.3765 112.893C74.0025 112.893 73.6652 112.819 73.3645 112.673C73.0712 112.519 72.8402 112.306 72.6715 112.035C72.5029 111.763 72.4185 111.459 72.4185 111.122C72.4185 110.799 72.4882 110.52 72.6275 110.286C72.7669 110.051 72.9685 109.875 73.2325 109.758C73.5845 109.596 74.0649 109.516 74.6735 109.516H76.0265V109.362C76.0265 109.068 75.9349 108.837 75.7515 108.669C75.5682 108.493 75.3189 108.405 75.0035 108.405C74.7249 108.405 74.4609 108.474 74.2115 108.614C73.9622 108.753 73.7385 108.955 73.5405 109.219L72.5835 108.416C73.2289 107.638 74.0429 107.25 75.0255 107.25ZM74.5855 111.771C74.9815 111.771 75.3189 111.65 75.5975 111.408C75.8835 111.158 76.0265 110.858 76.0265 110.506H74.8495C74.4242 110.506 74.1272 110.568 73.9585 110.693C73.8119 110.795 73.7385 110.946 73.7385 111.144C73.7385 111.334 73.8119 111.488 73.9585 111.606C74.1125 111.716 74.3215 111.771 74.5855 111.771ZM81.6089 105.116H82.9839V108.207H86.3389V105.116H87.7139V112.783H86.3389V109.472H82.9839V112.783H81.6089V105.116ZM94.1978 107.36V112.783H92.8778V112.156C92.6944 112.405 92.4598 112.592 92.1738 112.717C91.8951 112.834 91.5908 112.893 91.2608 112.893C90.6154 112.893 90.1314 112.691 89.8088 112.288C89.4861 111.884 89.3248 111.371 89.3248 110.748V107.36H90.6448V110.418C90.6448 110.762 90.7034 111.07 90.8208 111.342C90.9381 111.606 91.2131 111.738 91.6458 111.738C92.0271 111.738 92.3058 111.62 92.4818 111.386C92.6651 111.151 92.7751 110.88 92.8118 110.572C92.8558 110.264 92.8778 109.879 92.8778 109.417V107.36H94.1978ZM101.802 107.25C102.418 107.25 102.887 107.451 103.21 107.855C103.533 108.251 103.694 108.742 103.694 109.329V112.783H102.374V109.725C102.374 108.845 102.066 108.405 101.45 108.405C101.105 108.405 100.856 108.515 100.702 108.735C100.548 108.947 100.456 109.2 100.427 109.494C100.398 109.78 100.383 110.187 100.383 110.715V112.783H99.0629V109.725C99.0629 108.845 98.7586 108.405 98.1499 108.405C97.8053 108.405 97.5559 108.515 97.4019 108.735C97.2479 108.947 97.1526 109.204 97.1159 109.505C97.0866 109.798 97.0719 110.201 97.0719 110.715V112.783H95.7519L95.7409 107.36H97.0169V108.042C97.3249 107.514 97.8089 107.25 98.4689 107.25C98.8063 107.25 99.1143 107.33 99.3929 107.492C99.6789 107.653 99.8989 107.928 100.053 108.317C100.251 107.935 100.497 107.664 100.79 107.503C101.083 107.334 101.421 107.25 101.802 107.25ZM107.198 107.25C107.917 107.25 108.482 107.44 108.892 107.822C109.31 108.196 109.519 108.709 109.519 109.362V112.783H108.309L108.199 112.079C108.038 112.335 107.811 112.537 107.517 112.684C107.231 112.823 106.909 112.893 106.549 112.893C106.175 112.893 105.838 112.819 105.537 112.673C105.244 112.519 105.013 112.306 104.844 112.035C104.676 111.763 104.591 111.459 104.591 111.122C104.591 110.799 104.661 110.52 104.8 110.286C104.94 110.051 105.141 109.875 105.405 109.758C105.757 109.596 106.238 109.516 106.846 109.516H108.199V109.362C108.199 109.068 108.108 108.837 107.924 108.669C107.741 108.493 107.492 108.405 107.176 108.405C106.898 108.405 106.634 108.474 106.384 108.614C106.135 108.753 105.911 108.955 105.713 109.219L104.756 108.416C105.402 107.638 106.216 107.25 107.198 107.25ZM106.758 111.771C107.154 111.771 107.492 111.65 107.77 111.408C108.056 111.158 108.199 110.858 108.199 110.506H107.022C106.597 110.506 106.3 110.568 106.131 110.693C105.985 110.795 105.911 110.946 105.911 111.144C105.911 111.334 105.985 111.488 106.131 111.606C106.285 111.716 106.494 111.771 106.758 111.771ZM113.868 107.25C114.477 107.25 114.946 107.429 115.276 107.789C115.613 108.141 115.782 108.639 115.782 109.285V112.783H114.462V109.615C114.462 109.285 114.403 109.002 114.286 108.768C114.169 108.526 113.894 108.405 113.461 108.405C113.08 108.405 112.797 108.515 112.614 108.735C112.438 108.947 112.328 109.204 112.284 109.505C112.247 109.798 112.229 110.168 112.229 110.616V112.783H110.909V107.36H112.229V107.987C112.412 107.737 112.643 107.554 112.922 107.437C113.208 107.312 113.523 107.25 113.868 107.25ZM31.646 124.948C30.898 124.948 30.2417 124.786 29.677 124.464C29.1197 124.134 28.687 123.668 28.379 123.067C28.0783 122.458 27.928 121.75 27.928 120.944C27.928 120.137 28.0783 119.433 28.379 118.832C28.687 118.223 29.1197 117.757 29.677 117.435C30.2417 117.105 30.898 116.94 31.646 116.94C32.46 116.94 33.1603 117.134 33.747 117.523C34.3337 117.904 34.7663 118.458 35.045 119.184L33.78 119.679C33.6113 119.202 33.3437 118.846 32.977 118.612C32.6177 118.37 32.174 118.249 31.646 118.249C30.9053 118.249 30.3297 118.483 29.919 118.953C29.5083 119.415 29.303 120.075 29.303 120.933C29.303 121.791 29.5083 122.458 29.919 122.935C30.3297 123.404 30.9053 123.639 31.646 123.639C32.174 123.639 32.6213 123.518 32.988 123.276C33.3547 123.026 33.6187 122.66 33.78 122.176L35.067 122.66C34.7957 123.4 34.363 123.969 33.769 124.365C33.175 124.753 32.4673 124.948 31.646 124.948ZM40.5162 122C40.5162 122.161 40.5052 122.33 40.4832 122.506H36.7652C36.7946 122.872 36.9229 123.162 37.1502 123.375C37.3776 123.587 37.7002 123.694 38.1182 123.694C38.6462 123.694 39.0789 123.499 39.4162 123.111L40.3292 123.914C40.0286 124.244 39.6949 124.489 39.3282 124.651C38.9689 124.812 38.5619 124.893 38.1072 124.893C37.5132 124.893 37.0146 124.764 36.6112 124.508C36.2152 124.251 35.9219 123.914 35.7312 123.496C35.5406 123.07 35.4452 122.605 35.4452 122.099C35.4452 121.6 35.5369 121.134 35.7202 120.702C35.9109 120.269 36.1969 119.921 36.5782 119.657C36.9669 119.385 37.4472 119.25 38.0192 119.25C38.5619 119.25 39.0202 119.371 39.3942 119.613C39.7682 119.855 40.0469 120.185 40.2302 120.603C40.4209 121.021 40.5162 121.486 40.5162 122ZM39.2512 121.461C39.2439 121.123 39.1229 120.856 38.8882 120.658C38.6536 120.452 38.3602 120.35 38.0082 120.35C37.6342 120.35 37.3409 120.46 37.1282 120.68C36.9229 120.892 36.7982 121.153 36.7542 121.461H39.2512ZM42.8213 124.893C42.4327 124.893 42.121 124.775 41.8863 124.541C41.659 124.306 41.5453 123.954 41.5453 123.485V117.116H42.8653V123.397C42.8653 123.624 42.9937 123.738 43.2503 123.738C43.375 123.738 43.5143 123.716 43.6683 123.672V124.728C43.375 124.838 43.0927 124.893 42.8213 124.893ZM45.8828 124.893C45.4942 124.893 45.1825 124.775 44.9478 124.541C44.7205 124.306 44.6068 123.954 44.6068 123.485V117.116H45.9268V123.397C45.9268 123.624 46.0552 123.738 46.3118 123.738C46.4365 123.738 46.5758 123.716 46.7298 123.672V124.728C46.4365 124.838 46.1542 124.893 45.8828 124.893ZM54.7542 123.199H51.7512L51.1682 124.783H49.6722L52.7412 117.116H53.7752L56.8332 124.783H55.3372L54.7542 123.199ZM54.2922 121.934L53.2582 119.14L52.2242 121.934H54.2922ZM58.9421 120.405V123.166C58.9421 123.378 59.0007 123.536 59.1181 123.639C59.2427 123.741 59.4151 123.793 59.6351 123.793C59.8184 123.793 60.0384 123.752 60.2951 123.672V124.728C59.9651 124.838 59.6351 124.893 59.3051 124.893C58.8137 124.893 58.4104 124.761 58.0951 124.497C57.7797 124.225 57.6221 123.815 57.6221 123.265V120.405H56.7421V119.36H57.6221V118.095L58.9421 117.116V119.36H60.2951V120.405H58.9421ZM62.4043 124.893C62.0157 124.893 61.704 124.775 61.4693 124.541C61.242 124.306 61.1283 123.954 61.1283 123.485V117.116H62.4483V123.397C62.4483 123.624 62.5767 123.738 62.8333 123.738C62.958 123.738 63.0973 123.716 63.2513 123.672V124.728C62.958 124.838 62.6757 124.893 62.4043 124.893ZM66.3136 119.25C67.0323 119.25 67.597 119.44 68.0076 119.822C68.4256 120.196 68.6346 120.709 68.6346 121.362V124.783H67.4246L67.3146 124.079C67.1533 124.335 66.926 124.537 66.6326 124.684C66.3466 124.823 66.024 124.893 65.6646 124.893C65.2906 124.893 64.9533 124.819 64.6526 124.673C64.3593 124.519 64.1283 124.306 63.9596 124.035C63.791 123.763 63.7066 123.459 63.7066 123.122C63.7066 122.799 63.7763 122.52 63.9156 122.286C64.055 122.051 64.2566 121.875 64.5206 121.758C64.8726 121.596 65.353 121.516 65.9616 121.516H67.3146V121.362C67.3146 121.068 67.223 120.837 67.0396 120.669C66.8563 120.493 66.607 120.405 66.2916 120.405C66.013 120.405 65.749 120.474 65.4996 120.614C65.2503 120.753 65.0266 120.955 64.8286 121.219L63.8716 120.416C64.517 119.638 65.331 119.25 66.3136 119.25ZM65.8736 123.771C66.2696 123.771 66.607 123.65 66.8856 123.408C67.1716 123.158 67.3146 122.858 67.3146 122.506H66.1376C65.7123 122.506 65.4153 122.568 65.2466 122.693C65.1 122.795 65.0266 122.946 65.0266 123.144C65.0266 123.334 65.1 123.488 65.2466 123.606C65.4006 123.716 65.6096 123.771 65.8736 123.771ZM71.7292 124.893C71.1792 124.893 70.6952 124.75 70.2772 124.464C69.8665 124.17 69.5915 123.807 69.4522 123.375L70.5082 122.902C70.7208 123.496 71.1058 123.793 71.6632 123.793C71.9492 123.793 72.1655 123.727 72.3122 123.595C72.4662 123.463 72.5432 123.316 72.5432 123.155C72.5432 122.993 72.4662 122.872 72.3122 122.792C72.1582 122.711 71.9052 122.619 71.5532 122.517C71.1865 122.421 70.8822 122.322 70.6402 122.22C70.3982 122.11 70.1892 121.945 70.0132 121.725C69.8372 121.497 69.7492 121.2 69.7492 120.834C69.7492 120.335 69.9398 119.946 70.3212 119.668C70.7098 119.389 71.1828 119.25 71.7402 119.25C72.2022 119.25 72.6092 119.352 72.9612 119.558C73.3132 119.763 73.5918 120.053 73.7972 120.427L72.7742 120.988C72.6642 120.782 72.5248 120.617 72.3562 120.493C72.1875 120.361 71.9675 120.295 71.6962 120.295C71.4908 120.295 71.3222 120.339 71.1902 120.427C71.0655 120.515 71.0032 120.625 71.0032 120.757C71.0032 120.903 71.0802 121.017 71.2342 121.098C71.3955 121.178 71.6412 121.263 71.9712 121.351C72.3525 121.461 72.6678 121.571 72.9172 121.681C73.1665 121.791 73.3828 121.959 73.5662 122.187C73.7495 122.414 73.8412 122.711 73.8412 123.078C73.8412 123.481 73.7385 123.818 73.5332 124.09C73.3352 124.361 73.0748 124.563 72.7522 124.695C72.4295 124.827 72.0885 124.893 71.7292 124.893Z" fill="black" /> <g class="al-2023-active-dots green" id="active dots_17"> <circle id="Ellipse 2765_17" cx="48.8447" cy="146.599" r="48.5676" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2767_17" cx="48.8449" cy="146.599" r="25.309" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2771_17" cx="48.8448" cy="146.599" r="13.0446" fill="white" stroke="#22704F" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot green" id="inactive dot_17" cx="48.8446" cy="146.599" r="10.2374" fill="#22704F" stroke="white" stroke-width="3" /> <circle class="overlay-dot green" id="inactive dot_17" cx="48.8446" cy="146.599" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="4-Pilot-Projects-for-a-Human-Cell-Atlas" data-milestone="pilot-projects-for-a-human-cell-atlas" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_44" d="M239.15 101.636L94.2209 149.03" stroke="#22704F" stroke-width="1.5" stroke-linecap="round"/> <path class="al-2023-svg-text" d="M62.2407 170.147H64.7487C65.6067 170.147 66.2557 170.334 66.6957 170.708C67.1357 171.075 67.3557 171.625 67.3557 172.358C67.3557 173.099 67.132 173.664 66.6847 174.052C66.2447 174.441 65.5994 174.635 64.7487 174.635H63.6047V177.814H62.2407V170.147ZM64.6057 173.37C65.0897 173.37 65.438 173.293 65.6507 173.139C65.8707 172.978 65.9807 172.725 65.9807 172.38C65.9807 172.036 65.8744 171.79 65.6617 171.643C65.449 171.489 65.097 171.412 64.6057 171.412H63.6047V173.37H64.6057ZM68.3699 172.391H69.6899V177.814H68.3699V172.391ZM68.3369 170.147H69.7229V171.368H68.3369V170.147ZM72.4483 177.924C72.0596 177.924 71.7479 177.807 71.5133 177.572C71.2859 177.338 71.1723 176.986 71.1723 176.516V170.147H72.4923V176.428C72.4923 176.656 72.6206 176.769 72.8773 176.769C73.0019 176.769 73.1413 176.747 73.2953 176.703V177.759C73.0019 177.869 72.7196 177.924 72.4483 177.924ZM76.5218 177.924C75.9791 177.924 75.4988 177.8 75.0808 177.55C74.6701 177.294 74.3548 176.949 74.1348 176.516C73.9148 176.084 73.8048 175.611 73.8048 175.097C73.8048 174.584 73.9148 174.115 74.1348 173.689C74.3548 173.257 74.6701 172.916 75.0808 172.666C75.4988 172.41 75.9791 172.281 76.5218 172.281C77.0645 172.281 77.5411 172.41 77.9518 172.666C78.3625 172.916 78.6778 173.257 78.8978 173.689C79.1251 174.115 79.2388 174.584 79.2388 175.097C79.2388 175.611 79.1251 176.084 78.8978 176.516C78.6778 176.949 78.3625 177.294 77.9518 177.55C77.5411 177.8 77.0645 177.924 76.5218 177.924ZM76.5218 176.769C76.9911 176.769 77.3395 176.612 77.5668 176.296C77.8015 175.981 77.9188 175.581 77.9188 175.097C77.9188 174.613 77.8015 174.217 77.5668 173.909C77.3395 173.594 76.9911 173.436 76.5218 173.436C76.0525 173.436 75.7005 173.594 75.4658 173.909C75.2385 174.217 75.1248 174.613 75.1248 175.097C75.1248 175.581 75.2385 175.981 75.4658 176.296C75.7005 176.612 76.0525 176.769 76.5218 176.769ZM81.8122 173.436V176.197C81.8122 176.41 81.8709 176.568 81.9882 176.67C82.1129 176.773 82.2852 176.824 82.5052 176.824C82.6885 176.824 82.9085 176.784 83.1652 176.703V177.759C82.8352 177.869 82.5052 177.924 82.1752 177.924C81.6839 177.924 81.2805 177.792 80.9652 177.528C80.6499 177.257 80.4922 176.846 80.4922 176.296V173.436H79.6122V172.391H80.4922V171.126L81.8122 170.147V172.391H83.1652V173.436H81.8122ZM87.1626 170.147H89.6706C90.5286 170.147 91.1776 170.334 91.6176 170.708C92.0576 171.075 92.2776 171.625 92.2776 172.358C92.2776 173.099 92.0539 173.664 91.6066 174.052C91.1666 174.441 90.5212 174.635 89.6706 174.635H88.5266V177.814H87.1626V170.147ZM89.5276 173.37C90.0116 173.37 90.3599 173.293 90.5726 173.139C90.7926 172.978 90.9026 172.725 90.9026 172.38C90.9026 172.036 90.7962 171.79 90.5836 171.643C90.3709 171.489 90.0189 171.412 89.5276 171.412H88.5266V173.37H89.5276ZM95.9458 172.281C96.3052 172.281 96.6498 172.384 96.9798 172.589L96.3418 173.755C96.1512 173.631 95.9312 173.568 95.6818 173.568C94.8825 173.568 94.4828 174.074 94.4828 175.086V177.814H93.1628V172.391H94.4938V173.315C94.6038 172.993 94.7908 172.74 95.0548 172.556C95.3262 172.373 95.6232 172.281 95.9458 172.281ZM99.6068 177.924C99.0641 177.924 98.5838 177.8 98.1658 177.55C97.7551 177.294 97.4398 176.949 97.2198 176.516C96.9998 176.084 96.8898 175.611 96.8898 175.097C96.8898 174.584 96.9998 174.115 97.2198 173.689C97.4398 173.257 97.7551 172.916 98.1658 172.666C98.5838 172.41 99.0641 172.281 99.6068 172.281C100.149 172.281 100.626 172.41 101.037 172.666C101.447 172.916 101.763 173.257 101.983 173.689C102.21 174.115 102.324 174.584 102.324 175.097C102.324 175.611 102.21 176.084 101.983 176.516C101.763 176.949 101.447 177.294 101.037 177.55C100.626 177.8 100.149 177.924 99.6068 177.924ZM99.6068 176.769C100.076 176.769 100.424 176.612 100.652 176.296C100.886 175.981 101.004 175.581 101.004 175.097C101.004 174.613 100.886 174.217 100.652 173.909C100.424 173.594 100.076 173.436 99.6068 173.436C99.1374 173.436 98.7854 173.594 98.5508 173.909C98.3234 174.217 98.2098 174.613 98.2098 175.097C98.2098 175.581 98.3234 175.981 98.5508 176.296C98.7854 176.612 99.1374 176.769 99.6068 176.769ZM103.434 180.168C103.17 180.168 102.887 180.113 102.587 180.003V178.947C102.741 178.991 102.88 179.013 103.005 179.013C103.261 179.013 103.39 178.9 103.39 178.672V172.391H104.71V178.76C104.71 179.23 104.592 179.582 104.358 179.816C104.13 180.051 103.822 180.168 103.434 180.168ZM103.357 170.147H104.743V171.368H103.357V170.147ZM110.878 175.031C110.878 175.193 110.867 175.361 110.845 175.537H107.127C107.156 175.904 107.284 176.194 107.512 176.406C107.739 176.619 108.062 176.725 108.48 176.725C109.008 176.725 109.44 176.531 109.778 176.142L110.691 176.945C110.39 177.275 110.056 177.521 109.69 177.682C109.33 177.844 108.923 177.924 108.469 177.924C107.875 177.924 107.376 177.796 106.973 177.539C106.577 177.283 106.283 176.945 106.093 176.527C105.902 176.102 105.807 175.636 105.807 175.13C105.807 174.632 105.898 174.166 106.082 173.733C106.272 173.301 106.558 172.952 106.94 172.688C107.328 172.417 107.809 172.281 108.381 172.281C108.923 172.281 109.382 172.402 109.756 172.644C110.13 172.886 110.408 173.216 110.592 173.634C110.782 174.052 110.878 174.518 110.878 175.031ZM109.613 174.492C109.605 174.155 109.484 173.887 109.25 173.689C109.015 173.484 108.722 173.381 108.37 173.381C107.996 173.381 107.702 173.491 107.49 173.711C107.284 173.924 107.16 174.184 107.116 174.492H109.613ZM114.118 177.924C113.553 177.924 113.073 177.796 112.677 177.539C112.281 177.275 111.984 176.931 111.786 176.505C111.588 176.073 111.489 175.611 111.489 175.119C111.489 174.621 111.588 174.159 111.786 173.733C111.984 173.301 112.277 172.952 112.666 172.688C113.062 172.417 113.542 172.281 114.107 172.281C114.657 172.281 115.133 172.417 115.537 172.688C115.94 172.952 116.244 173.348 116.45 173.876L115.196 174.371C115.122 174.085 114.987 173.858 114.789 173.689C114.598 173.521 114.371 173.436 114.107 173.436C113.681 173.436 113.362 173.598 113.15 173.92C112.944 174.243 112.842 174.643 112.842 175.119C112.842 175.596 112.944 175.992 113.15 176.307C113.355 176.615 113.674 176.769 114.107 176.769C114.371 176.769 114.598 176.689 114.789 176.527C114.987 176.359 115.122 176.135 115.196 175.856L116.395 176.318C116.211 176.824 115.918 177.22 115.515 177.506C115.119 177.785 114.653 177.924 114.118 177.924ZM118.937 173.436V176.197C118.937 176.41 118.996 176.568 119.113 176.67C119.238 176.773 119.41 176.824 119.63 176.824C119.814 176.824 120.034 176.784 120.29 176.703V177.759C119.96 177.869 119.63 177.924 119.3 177.924C118.809 177.924 118.406 177.792 118.09 177.528C117.775 177.257 117.617 176.846 117.617 176.296V173.436H116.737V172.391H117.617V171.126L118.937 170.147V172.391H120.29V173.436H118.937ZM123.27 177.924C122.72 177.924 122.236 177.781 121.818 177.495C121.407 177.202 121.132 176.839 120.993 176.406L122.049 175.933C122.262 176.527 122.647 176.824 123.204 176.824C123.49 176.824 123.706 176.758 123.853 176.626C124.007 176.494 124.084 176.348 124.084 176.186C124.084 176.025 124.007 175.904 123.853 175.823C123.699 175.743 123.446 175.651 123.094 175.548C122.727 175.453 122.423 175.354 122.181 175.251C121.939 175.141 121.73 174.976 121.554 174.756C121.378 174.529 121.29 174.232 121.29 173.865C121.29 173.367 121.481 172.978 121.862 172.699C122.251 172.421 122.724 172.281 123.281 172.281C123.743 172.281 124.15 172.384 124.502 172.589C124.854 172.795 125.133 173.084 125.338 173.458L124.315 174.019C124.205 173.814 124.066 173.649 123.897 173.524C123.728 173.392 123.508 173.326 123.237 173.326C123.032 173.326 122.863 173.37 122.731 173.458C122.606 173.546 122.544 173.656 122.544 173.788C122.544 173.935 122.621 174.049 122.775 174.129C122.936 174.21 123.182 174.294 123.512 174.382C123.893 174.492 124.209 174.602 124.458 174.712C124.707 174.822 124.924 174.991 125.107 175.218C125.29 175.446 125.382 175.743 125.382 176.109C125.382 176.513 125.279 176.85 125.074 177.121C124.876 177.393 124.616 177.594 124.293 177.726C123.97 177.858 123.629 177.924 123.27 177.924ZM64.1181 185.436H63.0841V184.391H64.1291V183.775C64.1291 182.617 64.6754 182.037 65.7681 182.037C66.1347 182.037 66.4757 182.111 66.7911 182.257L66.3621 183.269C66.2227 183.181 66.0724 183.137 65.9111 183.137C65.7057 183.137 65.5737 183.2 65.5151 183.324C65.4637 183.449 65.4381 183.596 65.4381 183.764V184.391H66.7031V185.436H65.4381V189.814H64.1181V185.436ZM69.5555 189.924C69.0128 189.924 68.5325 189.8 68.1145 189.55C67.7038 189.294 67.3885 188.949 67.1685 188.516C66.9485 188.084 66.8385 187.611 66.8385 187.097C66.8385 186.584 66.9485 186.115 67.1685 185.689C67.3885 185.257 67.7038 184.916 68.1145 184.666C68.5325 184.41 69.0128 184.281 69.5555 184.281C70.0982 184.281 70.5748 184.41 70.9855 184.666C71.3962 184.916 71.7115 185.257 71.9315 185.689C72.1588 186.115 72.2725 186.584 72.2725 187.097C72.2725 187.611 72.1588 188.084 71.9315 188.516C71.7115 188.949 71.3962 189.294 70.9855 189.55C70.5748 189.8 70.0982 189.924 69.5555 189.924ZM69.5555 188.769C70.0248 188.769 70.3732 188.612 70.6005 188.296C70.8352 187.981 70.9525 187.581 70.9525 187.097C70.9525 186.613 70.8352 186.217 70.6005 185.909C70.3732 185.594 70.0248 185.436 69.5555 185.436C69.0862 185.436 68.7342 185.594 68.4995 185.909C68.2722 186.217 68.1585 186.613 68.1585 187.097C68.1585 187.581 68.2722 187.981 68.4995 188.296C68.7342 188.612 69.0862 188.769 69.5555 188.769ZM76.1104 184.281C76.4697 184.281 76.8144 184.384 77.1444 184.589L76.5064 185.755C76.3157 185.631 76.0957 185.568 75.8464 185.568C75.047 185.568 74.6474 186.074 74.6474 187.086V189.814H73.3274V184.391H74.6584V185.315C74.7684 184.993 74.9554 184.74 75.2194 184.556C75.4907 184.373 75.7877 184.281 76.1104 184.281ZM82.5612 184.281C83.2799 184.281 83.8445 184.472 84.2552 184.853C84.6732 185.227 84.8822 185.741 84.8822 186.393V189.814H83.6722L83.5622 189.11C83.4009 189.367 83.1735 189.569 82.8802 189.715C82.5942 189.855 82.2715 189.924 81.9122 189.924C81.5382 189.924 81.2009 189.851 80.9002 189.704C80.6069 189.55 80.3759 189.338 80.2072 189.066C80.0385 188.795 79.9542 188.491 79.9542 188.153C79.9542 187.831 80.0239 187.552 80.1632 187.317C80.3025 187.083 80.5042 186.907 80.7682 186.789C81.1202 186.628 81.6005 186.547 82.2092 186.547H83.5622V186.393C83.5622 186.1 83.4705 185.869 83.2872 185.7C83.1039 185.524 82.8545 185.436 82.5392 185.436C82.2605 185.436 81.9965 185.506 81.7472 185.645C81.4979 185.785 81.2742 185.986 81.0762 186.25L80.1192 185.447C80.7645 184.67 81.5785 184.281 82.5612 184.281ZM82.1212 188.802C82.5172 188.802 82.8545 188.681 83.1332 188.439C83.4192 188.19 83.5622 187.889 83.5622 187.537H82.3852C81.9599 187.537 81.6629 187.6 81.4942 187.724C81.3475 187.827 81.2742 187.977 81.2742 188.175C81.2742 188.366 81.3475 188.52 81.4942 188.637C81.6482 188.747 81.8572 188.802 82.1212 188.802ZM89.1445 182.147H90.5195V185.238H93.8745V182.147H95.2495V189.814H93.8745V186.503H90.5195V189.814H89.1445V182.147ZM101.733 184.391V189.814H100.413V189.187C100.23 189.437 99.9954 189.624 99.7094 189.748C99.4307 189.866 99.1264 189.924 98.7964 189.924C98.1511 189.924 97.6671 189.723 97.3444 189.319C97.0217 188.916 96.8604 188.403 96.8604 187.779V184.391H98.1804V187.449C98.1804 187.794 98.2391 188.102 98.3564 188.373C98.4737 188.637 98.7487 188.769 99.1814 188.769C99.5627 188.769 99.8414 188.652 100.017 188.417C100.201 188.183 100.311 187.911 100.347 187.603C100.391 187.295 100.413 186.91 100.413 186.448V184.391H101.733ZM109.338 184.281C109.954 184.281 110.423 184.483 110.746 184.886C111.068 185.282 111.23 185.774 111.23 186.36V189.814H109.91V186.756C109.91 185.876 109.602 185.436 108.986 185.436C108.641 185.436 108.392 185.546 108.238 185.766C108.084 185.979 107.992 186.232 107.963 186.525C107.933 186.811 107.919 187.218 107.919 187.746V189.814H106.599V186.756C106.599 185.876 106.294 185.436 105.686 185.436C105.341 185.436 105.092 185.546 104.938 185.766C104.784 185.979 104.688 186.236 104.652 186.536C104.622 186.83 104.608 187.233 104.608 187.746V189.814H103.288L103.277 184.391H104.553V185.073C104.861 184.545 105.345 184.281 106.005 184.281C106.342 184.281 106.65 184.362 106.929 184.523C107.215 184.685 107.435 184.96 107.589 185.348C107.787 184.967 108.032 184.696 108.326 184.534C108.619 184.366 108.956 184.281 109.338 184.281ZM114.734 184.281C115.453 184.281 116.017 184.472 116.428 184.853C116.846 185.227 117.055 185.741 117.055 186.393V189.814H115.845L115.735 189.11C115.574 189.367 115.346 189.569 115.053 189.715C114.767 189.855 114.444 189.924 114.085 189.924C113.711 189.924 113.374 189.851 113.073 189.704C112.78 189.55 112.549 189.338 112.38 189.066C112.211 188.795 112.127 188.491 112.127 188.153C112.127 187.831 112.197 187.552 112.336 187.317C112.475 187.083 112.677 186.907 112.941 186.789C113.293 186.628 113.773 186.547 114.382 186.547H115.735V186.393C115.735 186.1 115.643 185.869 115.46 185.7C115.277 185.524 115.027 185.436 114.712 185.436C114.433 185.436 114.169 185.506 113.92 185.645C113.671 185.785 113.447 185.986 113.249 186.25L112.292 185.447C112.937 184.67 113.751 184.281 114.734 184.281ZM114.294 188.802C114.69 188.802 115.027 188.681 115.306 188.439C115.592 188.19 115.735 187.889 115.735 187.537H114.558C114.133 187.537 113.836 187.6 113.667 187.724C113.52 187.827 113.447 187.977 113.447 188.175C113.447 188.366 113.52 188.52 113.667 188.637C113.821 188.747 114.03 188.802 114.294 188.802ZM121.404 184.281C122.012 184.281 122.482 184.461 122.812 184.82C123.149 185.172 123.318 185.671 123.318 186.316V189.814H121.998V186.646C121.998 186.316 121.939 186.034 121.822 185.799C121.704 185.557 121.429 185.436 120.997 185.436C120.615 185.436 120.333 185.546 120.15 185.766C119.974 185.979 119.864 186.236 119.82 186.536C119.783 186.83 119.765 187.2 119.765 187.647V189.814H118.445V184.391H119.765V185.018C119.948 184.769 120.179 184.586 120.458 184.468C120.744 184.344 121.059 184.281 121.404 184.281ZM74.2979 201.979C73.5499 201.979 72.8935 201.818 72.3289 201.495C71.7715 201.165 71.3389 200.7 71.0309 200.098C70.7302 199.49 70.5799 198.782 70.5799 197.975C70.5799 197.169 70.7302 196.465 71.0309 195.863C71.3389 195.255 71.7715 194.789 72.3289 194.466C72.8935 194.136 73.5499 193.971 74.2979 193.971C75.1119 193.971 75.8122 194.166 76.3989 194.554C76.9855 194.936 77.4182 195.489 77.6969 196.215L76.4319 196.71C76.2632 196.234 75.9955 195.878 75.6289 195.643C75.2695 195.401 74.8259 195.28 74.2979 195.28C73.5572 195.28 72.9815 195.515 72.5709 195.984C72.1602 196.446 71.9549 197.106 71.9549 197.964C71.9549 198.822 72.1602 199.49 72.5709 199.966C72.9815 200.436 73.5572 200.67 74.2979 200.67C74.8259 200.67 75.2732 200.549 75.6399 200.307C76.0065 200.058 76.2705 199.691 76.4319 199.207L77.7189 199.691C77.4475 200.432 77.0149 201 76.4209 201.396C75.8269 201.785 75.1192 201.979 74.2979 201.979ZM83.1681 199.031C83.1681 199.193 83.1571 199.361 83.1351 199.537H79.4171C79.4464 199.904 79.5747 200.194 79.8021 200.406C80.0294 200.619 80.3521 200.725 80.7701 200.725C81.2981 200.725 81.7307 200.531 82.0681 200.142L82.9811 200.945C82.6804 201.275 82.3467 201.521 81.9801 201.682C81.6207 201.844 81.2137 201.924 80.7591 201.924C80.1651 201.924 79.6664 201.796 79.2631 201.539C78.8671 201.283 78.5737 200.945 78.3831 200.527C78.1924 200.102 78.0971 199.636 78.0971 199.13C78.0971 198.632 78.1887 198.166 78.3721 197.733C78.5627 197.301 78.8487 196.952 79.2301 196.688C79.6187 196.417 80.0991 196.281 80.6711 196.281C81.2137 196.281 81.6721 196.402 82.0461 196.644C82.4201 196.886 82.6987 197.216 82.8821 197.634C83.0727 198.052 83.1681 198.518 83.1681 199.031ZM81.9031 198.492C81.8957 198.155 81.7747 197.887 81.5401 197.689C81.3054 197.484 81.0121 197.381 80.6601 197.381C80.2861 197.381 79.9927 197.491 79.7801 197.711C79.5747 197.924 79.4501 198.184 79.4061 198.492H81.9031ZM85.4732 201.924C85.0845 201.924 84.7728 201.807 84.5382 201.572C84.3108 201.338 84.1972 200.986 84.1972 200.516V194.147H85.5172V200.428C85.5172 200.656 85.6455 200.769 85.9022 200.769C86.0268 200.769 86.1662 200.747 86.3202 200.703V201.759C86.0268 201.869 85.7445 201.924 85.4732 201.924ZM88.5347 201.924C88.146 201.924 87.8344 201.807 87.5997 201.572C87.3724 201.338 87.2587 200.986 87.2587 200.516V194.147H88.5787V200.428C88.5787 200.656 88.707 200.769 88.9637 200.769C89.0884 200.769 89.2277 200.747 89.3817 200.703V201.759C89.0884 201.869 88.806 201.924 88.5347 201.924ZM97.406 200.23H94.403L93.82 201.814H92.324L95.393 194.147H96.427L99.485 201.814H97.989L97.406 200.23ZM96.944 198.965L95.91 196.171L94.876 198.965H96.944ZM101.594 197.436V200.197C101.594 200.41 101.653 200.568 101.77 200.67C101.895 200.773 102.067 200.824 102.287 200.824C102.47 200.824 102.69 200.784 102.947 200.703V201.759C102.617 201.869 102.287 201.924 101.957 201.924C101.466 201.924 101.062 201.792 100.747 201.528C100.432 201.257 100.274 200.846 100.274 200.296V197.436H99.3939V196.391H100.274V195.126L101.594 194.147V196.391H102.947V197.436H101.594ZM105.056 201.924C104.668 201.924 104.356 201.807 104.121 201.572C103.894 201.338 103.78 200.986 103.78 200.516V194.147H105.1V200.428C105.1 200.656 105.229 200.769 105.485 200.769C105.61 200.769 105.749 200.747 105.903 200.703V201.759C105.61 201.869 105.328 201.924 105.056 201.924ZM108.965 196.281C109.684 196.281 110.249 196.472 110.659 196.853C111.077 197.227 111.286 197.741 111.286 198.393V201.814H110.076L109.966 201.11C109.805 201.367 109.578 201.569 109.284 201.715C108.998 201.855 108.676 201.924 108.316 201.924C107.942 201.924 107.605 201.851 107.304 201.704C107.011 201.55 106.78 201.338 106.611 201.066C106.443 200.795 106.358 200.491 106.358 200.153C106.358 199.831 106.428 199.552 106.567 199.317C106.707 199.083 106.908 198.907 107.172 198.789C107.524 198.628 108.005 198.547 108.613 198.547H109.966V198.393C109.966 198.1 109.875 197.869 109.691 197.7C109.508 197.524 109.259 197.436 108.943 197.436C108.665 197.436 108.401 197.506 108.151 197.645C107.902 197.785 107.678 197.986 107.48 198.25L106.523 197.447C107.169 196.67 107.983 196.281 108.965 196.281ZM108.525 200.802C108.921 200.802 109.259 200.681 109.537 200.439C109.823 200.19 109.966 199.889 109.966 199.537H108.789C108.364 199.537 108.067 199.6 107.898 199.724C107.752 199.827 107.678 199.977 107.678 200.175C107.678 200.366 107.752 200.52 107.898 200.637C108.052 200.747 108.261 200.802 108.525 200.802ZM114.381 201.924C113.831 201.924 113.347 201.781 112.929 201.495C112.518 201.202 112.243 200.839 112.104 200.406L113.16 199.933C113.373 200.527 113.758 200.824 114.315 200.824C114.601 200.824 114.817 200.758 114.964 200.626C115.118 200.494 115.195 200.348 115.195 200.186C115.195 200.025 115.118 199.904 114.964 199.823C114.81 199.743 114.557 199.651 114.205 199.548C113.838 199.453 113.534 199.354 113.292 199.251C113.05 199.141 112.841 198.976 112.665 198.756C112.489 198.529 112.401 198.232 112.401 197.865C112.401 197.367 112.592 196.978 112.973 196.699C113.362 196.421 113.835 196.281 114.392 196.281C114.854 196.281 115.261 196.384 115.613 196.589C115.965 196.795 116.244 197.084 116.449 197.458L115.426 198.019C115.316 197.814 115.177 197.649 115.008 197.524C114.839 197.392 114.619 197.326 114.348 197.326C114.143 197.326 113.974 197.37 113.842 197.458C113.717 197.546 113.655 197.656 113.655 197.788C113.655 197.935 113.732 198.049 113.886 198.129C114.047 198.21 114.293 198.294 114.623 198.382C115.004 198.492 115.32 198.602 115.569 198.712C115.818 198.822 116.035 198.991 116.218 199.218C116.401 199.446 116.493 199.743 116.493 200.109C116.493 200.513 116.39 200.85 116.185 201.121C115.987 201.393 115.727 201.594 115.404 201.726C115.081 201.858 114.74 201.924 114.381 201.924Z" fill="black" /> <g class="al-2023-active-dots green" id="active dots_18"> <circle id="Ellipse 2765_18" cx="93.831" cy="146.506" r="48.5676" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2767_18" cx="93.8312" cy="146.505" r="25.309" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2771_18" cx="93.8311" cy="146.506" r="13.0446" fill="white" stroke="#22704F" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot green" id="inactive dot_18" cx="93.9135" cy="146.599" r="10.2374" fill="#22704F" stroke="white" stroke-width="3" /> <circle class="overlay-dot green" id="inactive dot_18" cx="93.9135" cy="146.599" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="3-Single-Cell-Biology" data-milestone="single-cell-biology" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_45" d="M432.725 48.8479L432.725 66.8789C432.725 74.0124 426.942 79.7952 419.809 79.7952L255.84 79.7952C248.707 79.7952 242.924 85.5779 242.924 92.7113L242.924 102.625" stroke="#21704F" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-connector-line reverse" id="connector-line_46" d="M625.955 102.625H244.353" stroke="url(#paint18_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M173.414 79.2997C172.908 79.2997 172.446 79.2044 172.028 79.0137C171.61 78.823 171.266 78.5554 170.994 78.2107C170.723 77.8587 170.551 77.4517 170.477 76.9897L171.841 76.6487C171.893 77.1034 172.058 77.4554 172.336 77.7047C172.622 77.954 172.989 78.0787 173.436 78.0787C173.825 78.0787 174.133 77.987 174.36 77.8037C174.588 77.6204 174.701 77.3674 174.701 77.0447C174.701 76.7807 174.588 76.5534 174.36 76.3627C174.14 76.172 173.744 75.963 173.172 75.7357C172.63 75.523 172.201 75.3104 171.885 75.0977C171.57 74.885 171.343 74.6467 171.203 74.3827C171.064 74.1114 170.994 73.7887 170.994 73.4147C170.994 73.004 171.093 72.641 171.291 72.3257C171.489 72.0104 171.768 71.7647 172.127 71.5887C172.494 71.4127 172.912 71.3247 173.381 71.3247C173.902 71.3247 174.36 71.442 174.756 71.6767C175.152 71.9114 175.471 72.2597 175.713 72.7217L174.569 73.4257C174.437 73.1397 174.265 72.9234 174.052 72.7767C173.84 72.6227 173.601 72.5457 173.337 72.5457C173.066 72.5457 172.835 72.6264 172.644 72.7877C172.461 72.949 172.369 73.147 172.369 73.3817C172.369 73.631 172.479 73.8437 172.699 74.0197C172.919 74.1957 173.315 74.3974 173.887 74.6247C174.445 74.8374 174.881 75.05 175.196 75.2627C175.512 75.4754 175.735 75.7137 175.867 75.9777C176.007 76.2344 176.076 76.5497 176.076 76.9237C176.076 77.393 175.963 77.8074 175.735 78.1667C175.515 78.526 175.204 78.8047 174.8 79.0027C174.397 79.2007 173.935 79.2997 173.414 79.2997ZM177.118 73.7337H178.438V79.1567H177.118V73.7337ZM177.085 71.4897H178.471V72.7107H177.085V71.4897ZM182.934 73.6237C183.543 73.6237 184.012 73.8034 184.342 74.1627C184.68 74.5147 184.848 75.0134 184.848 75.6587V79.1567H183.528V75.9887C183.528 75.6587 183.47 75.3764 183.352 75.1417C183.235 74.8997 182.96 74.7787 182.527 74.7787C182.146 74.7787 181.864 74.8887 181.68 75.1087C181.504 75.3214 181.394 75.578 181.35 75.8787C181.314 76.172 181.295 76.5424 181.295 76.9897V79.1567H179.975V73.7337H181.295V74.3607C181.479 74.1114 181.71 73.928 181.988 73.8107C182.274 73.686 182.59 73.6237 182.934 73.6237ZM188.349 78.3317C188.907 78.405 189.343 78.4784 189.658 78.5517C189.974 78.625 190.252 78.768 190.494 78.9807C190.744 79.1934 190.868 79.4977 190.868 79.8937C190.868 80.4364 190.645 80.8397 190.197 81.1037C189.75 81.375 189.141 81.5107 188.371 81.5107C187.557 81.5107 186.93 81.364 186.49 81.0707C186.05 80.7774 185.83 80.352 185.83 79.7947C185.83 79.7067 185.838 79.626 185.852 79.5527L186.633 79.0577C186.201 78.823 185.984 78.4527 185.984 77.9467C185.984 77.514 186.153 77.151 186.49 76.8577C186.197 76.491 186.05 76.0767 186.05 75.6147C186.05 75.2334 186.149 74.8924 186.347 74.5917C186.553 74.2837 186.824 74.0454 187.161 73.8767C187.499 73.708 187.869 73.6237 188.272 73.6237C188.749 73.6237 189.174 73.7374 189.548 73.9647L190.373 73.2607L191.066 74.0967L190.285 74.7347C190.439 75.028 190.516 75.3434 190.516 75.6807C190.516 76.0694 190.417 76.414 190.219 76.7147C190.021 77.0154 189.754 77.25 189.416 77.4187C189.079 77.58 188.712 77.6607 188.316 77.6607C187.957 77.6607 187.609 77.591 187.271 77.4517C187.169 77.5177 187.117 77.613 187.117 77.7377C187.117 77.921 187.22 78.053 187.425 78.1337C187.631 78.2144 187.939 78.2804 188.349 78.3317ZM188.294 74.7237C188.016 74.7237 187.792 74.808 187.623 74.9767C187.455 75.1454 187.37 75.369 187.37 75.6477C187.37 75.919 187.451 76.1427 187.612 76.3187C187.774 76.4947 188.001 76.5827 188.294 76.5827C188.588 76.5827 188.811 76.4984 188.965 76.3297C189.119 76.1537 189.196 75.9264 189.196 75.6477C189.196 75.369 189.116 75.1454 188.954 74.9767C188.793 74.808 188.573 74.7237 188.294 74.7237ZM188.426 80.5207C188.742 80.5207 189.006 80.4804 189.218 80.3997C189.438 80.319 189.548 80.1907 189.548 80.0147C189.548 79.846 189.449 79.7287 189.251 79.6627C189.053 79.5967 188.742 79.5344 188.316 79.4757L188.074 79.4427L187.623 79.3767L187.15 79.8277C187.143 79.8497 187.139 79.879 187.139 79.9157C187.139 80.1284 187.264 80.2824 187.513 80.3777C187.763 80.473 188.067 80.5207 188.426 80.5207ZM193.142 79.2667C192.753 79.2667 192.441 79.1494 192.207 78.9147C191.979 78.68 191.866 78.328 191.866 77.8587V71.4897H193.186V77.7707C193.186 77.998 193.314 78.1117 193.571 78.1117C193.695 78.1117 193.835 78.0897 193.989 78.0457V79.1017C193.695 79.2117 193.413 79.2667 193.142 79.2667ZM199.602 76.3737C199.602 76.535 199.591 76.7037 199.569 76.8797H195.851C195.881 77.2464 196.009 77.536 196.236 77.7487C196.464 77.9614 196.786 78.0677 197.204 78.0677C197.732 78.0677 198.165 77.8734 198.502 77.4847L199.415 78.2877C199.115 78.6177 198.781 78.8634 198.414 79.0247C198.055 79.186 197.648 79.2667 197.193 79.2667C196.599 79.2667 196.101 79.1384 195.697 78.8817C195.301 78.625 195.008 78.2877 194.817 77.8697C194.627 77.4444 194.531 76.9787 194.531 76.4727C194.531 75.974 194.623 75.5084 194.806 75.0757C194.997 74.643 195.283 74.2947 195.664 74.0307C196.053 73.7594 196.533 73.6237 197.105 73.6237C197.648 73.6237 198.106 73.7447 198.48 73.9867C198.854 74.2287 199.133 74.5587 199.316 74.9767C199.507 75.3947 199.602 75.8604 199.602 76.3737ZM198.337 75.8347C198.33 75.4974 198.209 75.2297 197.974 75.0317C197.74 74.8264 197.446 74.7237 197.094 74.7237C196.72 74.7237 196.427 74.8337 196.214 75.0537C196.009 75.2664 195.884 75.5267 195.84 75.8347H198.337ZM200.664 75.4057H203.832V76.3957H200.664V75.4057ZM208.714 79.3217C207.966 79.3217 207.31 79.1604 206.745 78.8377C206.188 78.5077 205.755 78.042 205.447 77.4407C205.147 76.832 204.996 76.1244 204.996 75.3177C204.996 74.511 205.147 73.807 205.447 73.2057C205.755 72.597 206.188 72.1314 206.745 71.8087C207.31 71.4787 207.966 71.3137 208.714 71.3137C209.528 71.3137 210.229 71.508 210.815 71.8967C211.402 72.278 211.835 72.8317 212.113 73.5577L210.848 74.0527C210.68 73.576 210.412 73.2204 210.045 72.9857C209.686 72.7437 209.242 72.6227 208.714 72.6227C207.974 72.6227 207.398 72.8574 206.987 73.3267C206.577 73.7887 206.371 74.4487 206.371 75.3067C206.371 76.1647 206.577 76.832 206.987 77.3087C207.398 77.778 207.974 78.0127 208.714 78.0127C209.242 78.0127 209.69 77.8917 210.056 77.6497C210.423 77.4004 210.687 77.0337 210.848 76.5497L212.135 77.0337C211.864 77.7744 211.431 78.3427 210.837 78.7387C210.243 79.1274 209.536 79.3217 208.714 79.3217ZM217.585 76.3737C217.585 76.535 217.574 76.7037 217.552 76.8797H213.834C213.863 77.2464 213.991 77.536 214.219 77.7487C214.446 77.9614 214.769 78.0677 215.187 78.0677C215.715 78.0677 216.147 77.8734 216.485 77.4847L217.398 78.2877C217.097 78.6177 216.763 78.8634 216.397 79.0247C216.037 79.186 215.63 79.2667 215.176 79.2667C214.582 79.2667 214.083 79.1384 213.68 78.8817C213.284 78.625 212.99 78.2877 212.8 77.8697C212.609 77.4444 212.514 76.9787 212.514 76.4727C212.514 75.974 212.605 75.5084 212.789 75.0757C212.979 74.643 213.265 74.2947 213.647 74.0307C214.035 73.7594 214.516 73.6237 215.088 73.6237C215.63 73.6237 216.089 73.7447 216.463 73.9867C216.837 74.2287 217.115 74.5587 217.299 74.9767C217.489 75.3947 217.585 75.8604 217.585 76.3737ZM216.32 75.8347C216.312 75.4974 216.191 75.2297 215.957 75.0317C215.722 74.8264 215.429 74.7237 215.077 74.7237C214.703 74.7237 214.409 74.8337 214.197 75.0537C213.991 75.2664 213.867 75.5267 213.823 75.8347H216.32ZM219.89 79.2667C219.501 79.2667 219.189 79.1494 218.955 78.9147C218.727 78.68 218.614 78.328 218.614 77.8587V71.4897H219.934V77.7707C219.934 77.998 220.062 78.1117 220.319 78.1117C220.443 78.1117 220.583 78.0897 220.737 78.0457V79.1017C220.443 79.2117 220.161 79.2667 219.89 79.2667ZM222.951 79.2667C222.563 79.2667 222.251 79.1494 222.016 78.9147C221.789 78.68 221.675 78.328 221.675 77.8587V71.4897H222.995V77.7707C222.995 77.998 223.124 78.1117 223.38 78.1117C223.505 78.1117 223.644 78.0897 223.798 78.0457V79.1017C223.505 79.2117 223.223 79.2667 222.951 79.2667ZM188.993 85.4897H191.666C192.428 85.4897 193.022 85.662 193.448 86.0067C193.88 86.344 194.097 86.817 194.097 87.4257C194.097 87.785 194.023 88.104 193.877 88.3827C193.73 88.654 193.521 88.8667 193.25 89.0207C194.086 89.3214 194.504 89.952 194.504 90.9127C194.504 91.6167 194.284 92.1667 193.844 92.5627C193.404 92.9587 192.791 93.1567 192.007 93.1567H188.993V85.4897ZM191.666 88.5367C192.01 88.5367 192.271 88.4634 192.447 88.3167C192.63 88.17 192.722 87.9537 192.722 87.6677C192.722 87.3744 192.63 87.1507 192.447 86.9967C192.263 86.8354 192.003 86.7547 191.666 86.7547H190.368V88.5367H191.666ZM191.897 91.8917C192.278 91.8917 192.579 91.7964 192.799 91.6057C193.019 91.4077 193.129 91.14 193.129 90.8027C193.129 90.48 193.022 90.2344 192.81 90.0657C192.604 89.8897 192.3 89.8017 191.897 89.8017H190.368V91.8917H191.897ZM195.713 87.7337H197.033V93.1567H195.713V87.7337ZM195.68 85.4897H197.066V86.7107H195.68V85.4897ZM200.803 93.2667C200.261 93.2667 199.78 93.142 199.362 92.8927C198.952 92.636 198.636 92.2914 198.416 91.8587C198.196 91.426 198.086 90.953 198.086 90.4397C198.086 89.9264 198.196 89.457 198.416 89.0317C198.636 88.599 198.952 88.258 199.362 88.0087C199.78 87.752 200.261 87.6237 200.803 87.6237C201.346 87.6237 201.823 87.752 202.233 88.0087C202.644 88.258 202.959 88.599 203.179 89.0317C203.407 89.457 203.52 89.9264 203.52 90.4397C203.52 90.953 203.407 91.426 203.179 91.8587C202.959 92.2914 202.644 92.636 202.233 92.8927C201.823 93.142 201.346 93.2667 200.803 93.2667ZM200.803 92.1117C201.273 92.1117 201.621 91.954 201.848 91.6387C202.083 91.3234 202.2 90.9237 202.2 90.4397C202.2 89.9557 202.083 89.5597 201.848 89.2517C201.621 88.9364 201.273 88.7787 200.803 88.7787C200.334 88.7787 199.982 88.9364 199.747 89.2517C199.52 89.5597 199.406 89.9557 199.406 90.4397C199.406 90.9237 199.52 91.3234 199.747 91.6387C199.982 91.954 200.334 92.1117 200.803 92.1117ZM205.796 93.2667C205.407 93.2667 205.096 93.1494 204.861 92.9147C204.634 92.68 204.52 92.328 204.52 91.8587V85.4897H205.84V91.7707C205.84 91.998 205.968 92.1117 206.225 92.1117C206.35 92.1117 206.489 92.0897 206.643 92.0457V93.1017C206.35 93.2117 206.067 93.2667 205.796 93.2667ZM209.87 93.2667C209.327 93.2667 208.847 93.142 208.429 92.8927C208.018 92.636 207.703 92.2914 207.483 91.8587C207.263 91.426 207.153 90.953 207.153 90.4397C207.153 89.9264 207.263 89.457 207.483 89.0317C207.703 88.599 208.018 88.258 208.429 88.0087C208.847 87.752 209.327 87.6237 209.87 87.6237C210.412 87.6237 210.889 87.752 211.3 88.0087C211.71 88.258 212.026 88.599 212.246 89.0317C212.473 89.457 212.587 89.9264 212.587 90.4397C212.587 90.953 212.473 91.426 212.246 91.8587C212.026 92.2914 211.71 92.636 211.3 92.8927C210.889 93.142 210.412 93.2667 209.87 93.2667ZM209.87 92.1117C210.339 92.1117 210.687 91.954 210.915 91.6387C211.149 91.3234 211.267 90.9237 211.267 90.4397C211.267 89.9557 211.149 89.5597 210.915 89.2517C210.687 88.9364 210.339 88.7787 209.87 88.7787C209.4 88.7787 209.048 88.9364 208.814 89.2517C208.586 89.5597 208.473 89.9557 208.473 90.4397C208.473 90.9237 208.586 91.3234 208.814 91.6387C209.048 91.954 209.4 92.1117 209.87 92.1117ZM215.72 92.3317C216.278 92.405 216.714 92.4784 217.029 92.5517C217.345 92.625 217.623 92.768 217.865 92.9807C218.115 93.1934 218.239 93.4977 218.239 93.8937C218.239 94.4364 218.016 94.8397 217.568 95.1037C217.121 95.375 216.512 95.5107 215.742 95.5107C214.928 95.5107 214.301 95.364 213.861 95.0707C213.421 94.7774 213.201 94.352 213.201 93.7947C213.201 93.7067 213.209 93.626 213.223 93.5527L214.004 93.0577C213.572 92.823 213.355 92.4527 213.355 91.9467C213.355 91.514 213.524 91.151 213.861 90.8577C213.568 90.491 213.421 90.0767 213.421 89.6147C213.421 89.2334 213.52 88.8924 213.718 88.5917C213.924 88.2837 214.195 88.0454 214.532 87.8767C214.87 87.708 215.24 87.6237 215.643 87.6237C216.12 87.6237 216.545 87.7374 216.919 87.9647L217.744 87.2607L218.437 88.0967L217.656 88.7347C217.81 89.028 217.887 89.3434 217.887 89.6807C217.887 90.0694 217.788 90.414 217.59 90.7147C217.392 91.0154 217.125 91.25 216.787 91.4187C216.45 91.58 216.083 91.6607 215.687 91.6607C215.328 91.6607 214.98 91.591 214.642 91.4517C214.54 91.5177 214.488 91.613 214.488 91.7377C214.488 91.921 214.591 92.053 214.796 92.1337C215.002 92.2144 215.31 92.2804 215.72 92.3317ZM215.665 88.7237C215.387 88.7237 215.163 88.808 214.994 88.9767C214.826 89.1454 214.741 89.369 214.741 89.6477C214.741 89.919 214.822 90.1427 214.983 90.3187C215.145 90.4947 215.372 90.5827 215.665 90.5827C215.959 90.5827 216.182 90.4984 216.336 90.3297C216.49 90.1537 216.567 89.9264 216.567 89.6477C216.567 89.369 216.487 89.1454 216.325 88.9767C216.164 88.808 215.944 88.7237 215.665 88.7237ZM215.797 94.5207C216.113 94.5207 216.377 94.4804 216.589 94.3997C216.809 94.319 216.919 94.1907 216.919 94.0147C216.919 93.846 216.82 93.7287 216.622 93.6627C216.424 93.5967 216.113 93.5344 215.687 93.4757L215.445 93.4427L214.994 93.3767L214.521 93.8277C214.514 93.8497 214.51 93.879 214.51 93.9157C214.51 94.1284 214.635 94.2824 214.884 94.3777C215.134 94.473 215.438 94.5207 215.797 94.5207ZM220.536 93.0137L218.413 87.7337H219.865L221.24 91.4957L222.626 87.7337H224.078L220.998 95.4007H219.568L220.536 93.0137Z" fill="black" /> <g class="al-2023-active-dots green" id="active-dot"> <circle id="Ellipse 2765_19" cx="241.034" cy="101.598" r="48.5676" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2767_19" cx="241.035" cy="101.598" r="25.309" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse 2771_19" cx="241.034" cy="101.598" r="13.0446" fill="white" stroke="#22704F" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot green" id="inactive-dot" cx="241.034" cy="101.598" r="10.2374" fill="#22704F" stroke="white" stroke-width="3" /> <circle class="overlay-dot green" id="inactive-dot" cx="241.034" cy="101.598" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="2-Biohub-San-Francisco" data-milestone="biohub-san-francisco" class="al-2023-svg-milestone"> <path class="al-2023-connector-line" id="connector-line_47" d="M439.574 48.8482L439.574 66.8792C439.574 74.0127 445.356 79.7955 452.49 79.7955L616.458 79.7955C623.591 79.7955 629.374 85.5783 629.374 92.7117L629.374 102.625" stroke="url(#paint19_linear_42_3042)" stroke-width="1.5" stroke-linecap="round" /> <path class="al-2023-svg-text" d="M649.296 100.582V92.9145H651.969C653.498 92.9145 654.4 93.6405 654.4 94.8505C654.4 95.5655 654.092 96.1375 653.553 96.4455C654.378 96.7425 654.807 97.3805 654.807 98.3375C654.807 99.7455 653.872 100.582 652.31 100.582H649.296ZM650.671 95.9615H651.969C652.662 95.9615 653.025 95.6645 653.025 95.0925C653.025 94.5095 652.64 94.1795 651.969 94.1795H650.671V95.9615ZM650.671 99.3165H652.2C652.97 99.3165 653.432 98.8985 653.432 98.2275C653.432 97.5785 653.003 97.2265 652.2 97.2265H650.671V99.3165ZM655.983 94.1355V92.9145H657.369V94.1355H655.983ZM656.016 100.582V95.1585H657.336V100.582H656.016ZM661.106 100.692C659.423 100.692 658.389 99.3935 658.389 97.8645C658.389 96.3245 659.423 95.0485 661.106 95.0485C662.778 95.0485 663.823 96.3245 663.823 97.8645C663.823 99.3935 662.778 100.692 661.106 100.692ZM661.106 99.5365C662.107 99.5365 662.503 98.7445 662.503 97.8645C662.503 96.9735 662.107 96.2035 661.106 96.2035C660.105 96.2035 659.709 96.9735 659.709 97.8645C659.709 98.7445 660.105 99.5365 661.106 99.5365ZM667.848 95.0485C669.069 95.0485 669.762 95.7855 669.762 97.0835V100.582H668.442V97.4135C668.442 96.5885 668.123 96.2035 667.441 96.2035C666.572 96.2035 666.209 96.8525 666.209 98.4145V100.582H664.889V92.9145H666.209V95.7745C666.572 95.3015 667.133 95.0485 667.848 95.0485ZM674.562 95.1585H675.882V100.582H674.562V99.9545C674.177 100.472 673.583 100.692 672.945 100.692C671.581 100.692 671.009 99.7015 671.009 98.5465V95.1585H672.329V98.2165C672.329 98.5905 672.329 99.5365 673.33 99.5365C674.562 99.5365 674.562 98.1835 674.562 97.2155V95.1585ZM680.318 95.0485C681.649 95.0485 682.606 96.0935 682.606 97.8645C682.606 99.4925 681.792 100.692 680.318 100.692C679.735 100.692 679.13 100.505 678.756 100.043V100.582H677.436V92.9145H678.756V95.7085C679.097 95.3015 679.702 95.0485 680.318 95.0485ZM679.999 99.4705C680.879 99.4705 681.286 98.8765 681.286 97.8755C681.286 96.8635 680.868 96.2475 679.988 96.2475C679.042 96.2475 678.635 96.9735 678.635 97.8755C678.635 98.7775 679.042 99.4705 679.999 99.4705ZM688.803 100.725C687.274 100.725 686.086 99.8115 685.866 98.4145L687.23 98.0735C687.329 98.9865 687.934 99.5035 688.825 99.5035C689.595 99.5035 690.09 99.1185 690.09 98.4695C690.09 97.9415 689.694 97.6115 688.561 97.1605C686.955 96.5335 686.383 95.9505 686.383 94.8395C686.383 93.5965 687.34 92.7495 688.77 92.7495C689.804 92.7495 690.618 93.2225 691.102 94.1465L689.958 94.8505C689.694 94.2785 689.243 93.9705 688.726 93.9705C688.176 93.9705 687.758 94.3335 687.758 94.8065C687.758 95.3015 688.132 95.5985 689.276 96.0495C690.926 96.6765 691.465 97.2485 691.465 98.3485C691.465 99.7785 690.376 100.725 688.803 100.725ZM694.608 95.0485C696.038 95.0485 696.929 95.8515 696.929 97.1605V100.582H695.719L695.609 99.8775C695.29 100.384 694.674 100.692 693.959 100.692C692.815 100.692 692.001 99.9545 692.001 98.9205C692.001 98.2825 692.287 97.7985 692.815 97.5565C693.178 97.3915 693.64 97.3145 694.256 97.3145H695.609V97.1605C695.609 96.5665 695.213 96.2035 694.586 96.2035C694.036 96.2035 693.519 96.4895 693.123 97.0175L692.166 96.2145C692.815 95.4335 693.618 95.0485 694.608 95.0485ZM694.168 99.5695C694.96 99.5695 695.609 99.0085 695.609 98.3045H694.432C693.981 98.3045 693.717 98.3595 693.541 98.4915C693.398 98.5905 693.321 98.7445 693.321 98.9425C693.321 99.3275 693.64 99.5695 694.168 99.5695ZM701.278 95.0485C702.499 95.0485 703.192 95.7965 703.192 97.0835V100.582H701.872V97.4135C701.872 97.0395 701.872 96.2035 700.871 96.2035C699.639 96.2035 699.639 97.4465 699.639 98.4145V100.582H698.319V95.1585H699.639V95.7855C700.024 95.2685 700.618 95.0485 701.278 95.0485ZM649.296 112.582V104.915H654.73V106.18H650.671V108.006H654.246V109.271H650.671V112.582H649.296ZM658.165 107.049C658.528 107.049 658.847 107.137 659.199 107.357L658.561 108.523C658.374 108.402 658.165 108.336 657.901 108.336C657.098 108.336 656.702 108.831 656.702 109.854V112.582H655.382V107.159H656.713V108.083C656.944 107.412 657.549 107.049 658.165 107.049ZM662.006 107.049C663.436 107.049 664.327 107.852 664.327 109.161V112.582H663.117L663.007 111.878C662.688 112.384 662.072 112.692 661.357 112.692C660.213 112.692 659.399 111.955 659.399 110.921C659.399 110.283 659.685 109.799 660.213 109.557C660.576 109.392 661.038 109.315 661.654 109.315H663.007V109.161C663.007 108.567 662.611 108.204 661.984 108.204C661.434 108.204 660.917 108.49 660.521 109.018L659.564 108.215C660.213 107.434 661.016 107.049 662.006 107.049ZM661.566 111.57C662.358 111.57 663.007 111.009 663.007 110.305H661.83C661.379 110.305 661.115 110.36 660.939 110.492C660.796 110.591 660.719 110.745 660.719 110.943C660.719 111.328 661.038 111.57 661.566 111.57ZM668.675 107.049C669.896 107.049 670.589 107.797 670.589 109.084V112.582H669.269V109.414C669.269 109.04 669.269 108.204 668.268 108.204C667.036 108.204 667.036 109.447 667.036 110.415V112.582H665.716V107.159H667.036V107.786C667.421 107.269 668.015 107.049 668.675 107.049ZM674.167 112.692C672.396 112.692 671.538 111.317 671.538 109.887C671.538 108.457 672.385 107.049 674.156 107.049C675.234 107.049 676.081 107.566 676.499 108.644L675.245 109.139C675.102 108.567 674.695 108.204 674.156 108.204C673.243 108.204 672.891 109.029 672.891 109.887C672.891 110.745 673.232 111.537 674.156 111.537C674.684 111.537 675.102 111.185 675.245 110.624L676.444 111.086C676.081 112.098 675.245 112.692 674.167 112.692ZM677.414 106.136V104.915H678.8V106.136H677.414ZM677.447 112.582V107.159H678.767V112.582H677.447ZM682.009 112.692C680.865 112.692 679.996 111.999 679.732 111.174L680.788 110.701C680.931 111.097 681.217 111.592 681.943 111.592C682.559 111.592 682.823 111.24 682.823 110.954C682.823 110.041 680.029 110.646 680.029 108.633C680.029 107.588 680.975 107.049 682.02 107.049C682.955 107.049 683.67 107.489 684.077 108.226L683.054 108.787C682.867 108.446 682.57 108.094 681.976 108.094C681.547 108.094 681.283 108.303 681.283 108.556C681.283 109.381 684.121 108.897 684.121 110.877C684.121 112.142 683.032 112.692 682.009 112.692ZM687.369 112.692C685.598 112.692 684.74 111.317 684.74 109.887C684.74 108.457 685.587 107.049 687.358 107.049C688.436 107.049 689.283 107.566 689.701 108.644L688.447 109.139C688.304 108.567 687.897 108.204 687.358 108.204C686.445 108.204 686.093 109.029 686.093 109.887C686.093 110.745 686.434 111.537 687.358 111.537C687.886 111.537 688.304 111.185 688.447 110.624L689.646 111.086C689.283 112.098 688.447 112.692 687.369 112.692ZM692.828 112.692C691.145 112.692 690.111 111.394 690.111 109.865C690.111 108.325 691.145 107.049 692.828 107.049C694.5 107.049 695.545 108.325 695.545 109.865C695.545 111.394 694.5 112.692 692.828 112.692ZM692.828 111.537C693.829 111.537 694.225 110.745 694.225 109.865C694.225 108.974 693.829 108.204 692.828 108.204C691.827 108.204 691.431 108.974 691.431 109.865C691.431 110.745 691.827 111.537 692.828 111.537Z" fill="black" /> <g class="al-2023-active-dots navy" id="active-dots"> <circle id="Ellipse 2765_20" cx="630.374" cy="101.598" r="48.5676" fill="#4990C6" fill-opacity="0.1" /> <circle id="Ellipse 2767_20" cx="630.374" cy="101.598" r="25.309" fill="#4990C6" fill-opacity="0.3" /> <circle id="Ellipse 2771_20" cx="630.374" cy="101.598" r="13.0446" fill="white" stroke="#004375" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot navy" id="inactive-dot_2" cx="630.374" cy="101.599" r="10.2374" fill="#004375" stroke="white" stroke-width="3" /> <circle class="overlay-dot navy" id="inactive-dot_2" cx="630.374" cy="101.599" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> <g id="1-CZI-Science-Launches" data-milestone="czi-science-launches" class="al-2023-svg-milestone"> <path class="al-2023-svg-text" d="M469.187 47.996C466.921 47.996 465.469 46.445 465.469 43.992C465.469 41.539 466.921 39.988 469.187 39.988C470.804 39.988 472.025 40.769 472.586 42.232L471.321 42.727C470.98 41.77 470.232 41.297 469.187 41.297C467.702 41.297 466.844 42.265 466.844 43.981C466.844 45.708 467.713 46.687 469.187 46.687C470.243 46.687 470.991 46.192 471.321 45.224L472.608 45.708C472.058 47.193 470.826 47.996 469.187 47.996ZM479.329 40.164V41.165L475.028 46.566H479.329V47.831H473.147V46.874L477.492 41.429H473.4V40.164H479.329ZM480.682 47.831V40.164H482.057V47.831H480.682ZM488.866 47.974C487.337 47.974 486.149 47.061 485.929 45.664L487.293 45.323C487.392 46.236 487.997 46.753 488.888 46.753C489.658 46.753 490.153 46.368 490.153 45.719C490.153 45.191 489.757 44.861 488.624 44.41C487.018 43.783 486.446 43.2 486.446 42.089C486.446 40.846 487.403 39.999 488.833 39.999C489.867 39.999 490.681 40.472 491.165 41.396L490.021 42.1C489.757 41.528 489.306 41.22 488.789 41.22C488.239 41.22 487.821 41.583 487.821 42.056C487.821 42.551 488.195 42.848 489.339 43.299C490.989 43.926 491.528 44.498 491.528 45.598C491.528 47.028 490.439 47.974 488.866 47.974ZM494.704 47.941C492.933 47.941 492.075 46.566 492.075 45.136C492.075 43.706 492.922 42.298 494.693 42.298C495.771 42.298 496.618 42.815 497.036 43.893L495.782 44.388C495.639 43.816 495.232 43.453 494.693 43.453C493.78 43.453 493.428 44.278 493.428 45.136C493.428 45.994 493.769 46.786 494.693 46.786C495.221 46.786 495.639 46.434 495.782 45.873L496.981 46.335C496.618 47.347 495.782 47.941 494.704 47.941ZM497.951 41.385V40.164H499.337V41.385H497.951ZM497.984 47.831V42.408H499.304V47.831H497.984ZM505.461 45.048C505.461 45.213 505.45 45.378 505.428 45.554H501.71C501.765 46.269 502.205 46.742 503.063 46.742C503.547 46.742 503.987 46.588 504.361 46.159L505.274 46.962C504.68 47.622 503.965 47.941 503.052 47.941C501.182 47.941 500.39 46.599 500.39 45.147C500.39 43.728 501.16 42.298 502.964 42.298C504.647 42.298 505.461 43.541 505.461 45.048ZM501.699 44.509H504.196C504.174 43.816 503.646 43.398 502.953 43.398C502.15 43.398 501.776 43.97 501.699 44.509ZM509.504 42.298C510.725 42.298 511.418 43.046 511.418 44.333V47.831H510.098V44.663C510.098 44.289 510.098 43.453 509.097 43.453C507.865 43.453 507.865 44.696 507.865 45.664V47.831H506.545V42.408H507.865V43.035C508.25 42.518 508.844 42.298 509.504 42.298ZM514.996 47.941C513.225 47.941 512.367 46.566 512.367 45.136C512.367 43.706 513.214 42.298 514.985 42.298C516.063 42.298 516.91 42.815 517.328 43.893L516.074 44.388C515.931 43.816 515.524 43.453 514.985 43.453C514.072 43.453 513.72 44.278 513.72 45.136C513.72 45.994 514.061 46.786 514.985 46.786C515.513 46.786 515.931 46.434 516.074 45.873L517.273 46.335C516.91 47.347 516.074 47.941 514.996 47.941ZM522.842 45.048C522.842 45.213 522.831 45.378 522.809 45.554H519.091C519.146 46.269 519.586 46.742 520.444 46.742C520.928 46.742 521.368 46.588 521.742 46.159L522.655 46.962C522.061 47.622 521.346 47.941 520.433 47.941C518.563 47.941 517.771 46.599 517.771 45.147C517.771 43.728 518.541 42.298 520.345 42.298C522.028 42.298 522.842 43.541 522.842 45.048ZM519.08 44.509H521.577C521.555 43.816 521.027 43.398 520.334 43.398C519.531 43.398 519.157 43.97 519.08 44.509ZM466.019 59.831V52.164H467.394V58.566H470.672V59.831H466.019ZM473.702 54.298C475.132 54.298 476.023 55.101 476.023 56.41V59.831H474.813L474.703 59.127C474.384 59.633 473.768 59.941 473.053 59.941C471.909 59.941 471.095 59.204 471.095 58.17C471.095 57.532 471.381 57.048 471.909 56.806C472.272 56.641 472.734 56.564 473.35 56.564H474.703V56.41C474.703 55.816 474.307 55.453 473.68 55.453C473.13 55.453 472.613 55.739 472.217 56.267L471.26 55.464C471.909 54.683 472.712 54.298 473.702 54.298ZM473.262 58.819C474.054 58.819 474.703 58.258 474.703 57.554H473.526C473.075 57.554 472.811 57.609 472.635 57.741C472.492 57.84 472.415 57.994 472.415 58.192C472.415 58.577 472.734 58.819 473.262 58.819ZM480.758 54.408H482.078V59.831H480.758V59.204C480.373 59.721 479.779 59.941 479.141 59.941C477.777 59.941 477.205 58.951 477.205 57.796V54.408H478.525V57.466C478.525 57.84 478.525 58.786 479.526 58.786C480.758 58.786 480.758 57.433 480.758 56.465V54.408ZM486.58 54.298C487.801 54.298 488.494 55.046 488.494 56.333V59.831H487.174V56.663C487.174 56.289 487.174 55.453 486.173 55.453C484.941 55.453 484.941 56.696 484.941 57.664V59.831H483.621V54.408H484.941V55.035C485.326 54.518 485.92 54.298 486.58 54.298ZM492.072 59.941C490.301 59.941 489.443 58.566 489.443 57.136C489.443 55.706 490.29 54.298 492.061 54.298C493.139 54.298 493.986 54.815 494.404 55.893L493.15 56.388C493.007 55.816 492.6 55.453 492.061 55.453C491.148 55.453 490.796 56.278 490.796 57.136C490.796 57.994 491.137 58.786 492.061 58.786C492.589 58.786 493.007 58.434 493.15 57.873L494.349 58.335C493.986 59.347 493.15 59.941 492.072 59.941ZM498.322 54.298C499.543 54.298 500.236 55.035 500.236 56.333V59.831H498.916V56.663C498.916 55.838 498.597 55.453 497.915 55.453C497.046 55.453 496.683 56.102 496.683 57.664V59.831H495.363V52.164H496.683V55.024C497.046 54.551 497.607 54.298 498.322 54.298ZM506.277 57.048C506.277 57.213 506.266 57.378 506.244 57.554H502.526C502.581 58.269 503.021 58.742 503.879 58.742C504.363 58.742 504.803 58.588 505.177 58.159L506.09 58.962C505.496 59.622 504.781 59.941 503.868 59.941C501.998 59.941 501.206 58.599 501.206 57.147C501.206 55.728 501.976 54.298 503.78 54.298C505.463 54.298 506.277 55.541 506.277 57.048ZM502.515 56.509H505.012C504.99 55.816 504.462 55.398 503.769 55.398C502.966 55.398 502.592 55.97 502.515 56.509ZM509.066 59.941C507.922 59.941 507.053 59.248 506.789 58.423L507.845 57.95C507.988 58.346 508.274 58.841 509 58.841C509.616 58.841 509.88 58.489 509.88 58.203C509.88 57.29 507.086 57.895 507.086 55.882C507.086 54.837 508.032 54.298 509.077 54.298C510.012 54.298 510.727 54.738 511.134 55.475L510.111 56.036C509.924 55.695 509.627 55.343 509.033 55.343C508.604 55.343 508.34 55.552 508.34 55.805C508.34 56.63 511.178 56.146 511.178 58.126C511.178 59.391 510.089 59.941 509.066 59.941Z" fill="black" /> <g class="al-2023-active-dots black" id="active-dot_2"> <circle id="Ellipse-2765" cx="435.518" cy="48.8478" r="48.5676" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse-2767" cx="435.518" cy="48.8478" r="25.309" fill="#36AA79" fill-opacity="0.1" /> <circle id="Ellipse-2771" cx="435.518" cy="48.8478" r="14.9177" fill="white" stroke="#22704F" stroke-width="2.27933" /> </g> <circle class="al-2023-inactive-dot black" id="inactive-dot_3" cx="435.518" cy="48.8478" r="10.2374" fill="#22704F" stroke="white" stroke-width="3" /> <circle class="overlay-dot black" cx="435.518" cy="48.8478" r="10.2374" fill="#FF414B" stroke="white" stroke-width="3" /> </g> </g> </g> <defs> <linearGradient id="paint0_linear_42_3042" x1="436.021" y1="165.112" x2="436.021" y2="513.849" gradientUnits="userSpaceOnUse"> <stop offset="0.300897" stop-color="#4BC1C0" /> <stop offset="0.783827" stop-color="#FF414B" /> </linearGradient> <linearGradient id="paint1_linear_42_3042" x1="410.81" y1="426" x2="430.657" y2="463.252" gradientUnits="userSpaceOnUse"> <stop stop-color="#4BC1C0" /> <stop offset="0.910328" stop-color="#FF414B" /> </linearGradient> <linearGradient id="paint2_linear_42_3042" x1="414.594" y1="266" x2="498.77" y2="471.738" gradientUnits="userSpaceOnUse"> <stop stop-color="#4BC1C0" /> <stop offset="0.910328" stop-color="#FF414B" /> </linearGradient> <linearGradient id="paint3_linear_42_3042" x1="499.878" y1="444.917" x2="458.176" y2="467.027" gradientUnits="userSpaceOnUse"> <stop stop-color="#004375" /> <stop offset="1" stop-color="#FF414B" /> </linearGradient> <linearGradient id="paint4_linear_42_3042" x1="490.762" y1="443.878" x2="453.982" y2="461.694" gradientUnits="userSpaceOnUse"> <stop stop-color="#004375" /> <stop offset="1" stop-color="#FF414B" /> </linearGradient> <linearGradient id="paint5_linear_42_3042" x1="473.814" y1="442.89" x2="446.641" y2="452.412" gradientUnits="userSpaceOnUse"> <stop stop-color="#004375" /> <stop offset="1" stop-color="#FF414B" /> </linearGradient> <linearGradient id="paint6_linear_42_3042" x1="464.904" y1="443.549" x2="443.539" y2="448.843" gradientUnits="userSpaceOnUse"> <stop stop-color="#004375" /> <stop offset="1" stop-color="#FF414B" /> </linearGradient> <linearGradient id="paint7_linear_42_3042" x1="372.649" y1="417.065" x2="369.579" y2="387.839" gradientUnits="userSpaceOnUse"> <stop stop-color="#22704F" /> <stop offset="1" stop-color="#73DAD9" /> </linearGradient> <linearGradient id="paint8_linear_42_3042" x1="461.018" y1="298.336" x2="452.7" y2="417.856" gradientUnits="userSpaceOnUse"> <stop stop-color="#4BC1C0" /> <stop offset="0.489583" stop-color="#3B90A8" /> <stop offset="1" stop-color="#004375" /> </linearGradient> <linearGradient id="paint9_linear_42_3042" x1="454.913" y1="254.392" x2="555.61" y2="315.889" gradientUnits="userSpaceOnUse"> <stop stop-color="#4BC1C0" /> <stop offset="0.489583" stop-color="#3B90A8" /> <stop offset="1" stop-color="#004375" /> </linearGradient> <linearGradient id="paint10_linear_42_3042" x1="472.518" y1="307.723" x2="493.956" y2="374.602" gradientUnits="userSpaceOnUse"> <stop stop-color="#4BC1C0" /> <stop offset="0.489583" stop-color="#3B90A8" /> <stop offset="1" stop-color="#004375" /> </linearGradient> <linearGradient id="paint11_linear_42_3042" x1="156.36" y1="231.5" x2="579.883" y2="330.252" gradientUnits="userSpaceOnUse"> <stop stop-color="#21704F" /> <stop offset="1" stop-color="#004375" /> </linearGradient> <linearGradient id="paint12_linear_42_3042" x1="345.533" y1="458.472" x2="381.775" y2="411.042" gradientUnits="userSpaceOnUse"> <stop stop-color="#22704F" /> <stop offset="1" stop-color="#73DAD9" /> </linearGradient> <linearGradient id="paint13_linear_42_3042" x1="509.457" y1="153.553" x2="501.172" y2="255.715" gradientUnits="userSpaceOnUse"> <stop stop-color="#4BC1C0" /> <stop offset="1" stop-color="#004375" /> </linearGradient> <linearGradient id="paint14_linear_42_3042" x1="443.071" y1="405.184" x2="506.462" y2="416.862" gradientUnits="userSpaceOnUse"> <stop stop-color="#4BC1C0" /> <stop offset="0.489583" stop-color="#3B90A8" /> <stop offset="1" stop-color="#004375" /> </linearGradient> <linearGradient id="paint15_linear_42_3042" x1="336.483" y1="444.917" x2="426.105" y2="365.426" gradientUnits="userSpaceOnUse"> <stop stop-color="#22704F" /> <stop offset="1" stop-color="#4BC1C0" /> </linearGradient> <linearGradient id="paint16_linear_42_3042" x1="330.838" y1="449.056" x2="422.356" y2="357.038" gradientUnits="userSpaceOnUse"> <stop stop-color="#22704F" /> <stop offset="1" stop-color="#73DAD9" /> </linearGradient> <linearGradient id="paint17_linear_42_3042" x1="385.998" y1="143.205" x2="385.998" y2="55.6544" gradientUnits="userSpaceOnUse"> <stop stop-color="#73DAD9" /> <stop offset="1" stop-color="#22704F" /> </linearGradient> <linearGradient id="paint18_linear_42_3042" x1="358.393" y1="168.041" x2="553.054" y2="168.041" gradientUnits="userSpaceOnUse"> <stop stop-color="#22704F" /> <stop offset="1" stop-color="#004375" /> </linearGradient> <linearGradient id="paint19_linear_42_3042" x1="607.75" y1="91.75" x2="462.5" y2="65" gradientUnits="userSpaceOnUse"> <stop stop-color="#004375" /> <stop offset="0.938626" stop-color="#21704F" /> </linearGradient> <linearGradient id="paint20_linear_42_3042" x1="273.632" y1="334.484" x2="331.699" y2="334.484" gradientUnits="userSpaceOnUse"> <stop stop-color="#22704F"/> <stop offset="1" stop-color="#3FA99E"/> </linearGradient> <clipPath id="clip0_42_3042"> <rect width="835" height="619" fill="white" /> </clipPath> </defs> </svg> </div> </div> <div class="al-2023-milestones"> <div class="al-2023-milestones-inner"> <div class="al-2023-milestone" data-milestone="czi-science-launches"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/CZI-Science-Launches.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2016</div> </div> <h3 class="t-h5--semibold">CZI Science Launches</h3> <p>We launch our <a href="https://chanzuckerberg.com/science/" target="_blank" rel="noopener">science work</a>, focusing on building comprehensive datasets and computational tools to quickly access and analyze data, while spurring collaboration across interdisciplinary fields to share insights. We <span class="al-2023-milestone__highlight turqiose">build tools</span>, <span class="al-2023-milestone__highlight green">fund research</span> worldwide, and <span class="al-2023-milestone__highlight navy">do science</span> at our institutes through multidisciplinary collaboration to make discoveries about health and disease.</p> </div> </div> <div class="al-2023-milestone" data-milestone="biohub-san-francisco"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Biohub-San-Francisco.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2016</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">Chan Zuckerberg Biohub San Francisco</h3> <p>We launch the <a href="https://www.czbiohub.org/sf/" target="_blank" rel="noopener">San Francisco Biohub</a>, where the Bay Area's leading academic institutions (UC San Francisco, Stanford University, and UC Berkeley) join forces to pursue the toughest, riskiest scientific challenges in cell biology and infectious disease.</p> </div> </div> <div class="al-2023-milestone" data-milestone="single-cell-biology"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/scb.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2016</div> <div class="al-2023-milestone__label t-uppercase green">Fund Research</div> </div> <h3 class="t-h5--semibold">Single-Cell Biology</h3> <p>One of the first single-cell research efforts we support is the <a href="https://www.humancellatlas.org/" target="_blank" rel="noopener">Human Cell Atlas</a> — a global, scientist-led collaboration to map and characterize all cell types in the healthy human body. Additionally, the generation of cell atlases becomes a major focus of our partnership with the new San Francisco Biohub. As it evolves, the Human Cell Atlas continues to be an essential and foundational resource helping scientists better understand how healthy cells work. Data from the Human Cell Atlas will feed into one of the large-scale datasets that we use in building our AI model to predict cell types and states.</p> </div> </div> <div class="al-2023-milestone" data-milestone="pilot-projects-for-a-human-cell-atlas"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Pilot-Projects-for-a-Human-Cell-Atlas.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2017</div> <div class="al-2023-milestone__label t-uppercase green">Fund Research</div> </div> <h3 class="t-h5--semibold">Pilot Projects for a Human Cell Atlas</h3> <p>We fund our first grants to help <a href="https://chanzuckerberg.com/human-cell-atlas-pilot-projects/" target="_blank" rel="noopener">researchers</a> evaluate protocols and best practices for the collection of single-cell molecular data, which are then compiled for the Human Cell Atlas. One important result of this work: it lays the foundation for generating more data to support the <a href="https://www.nature.com/articles/s41586-020-2797-4" target="_blank" rel="noopener">Heart Cell Atlas</a> by increasing the number of known cells in the heart by an order of magnitude and identifying hundreds of marker genes for cardiac cell types in states.</p> </div> </div> <div class="al-2023-milestone" data-milestone="collaborative-computational-tools-for-a-human-cell-atlas"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Human-Cell-Atlas.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2017</div> <div class="al-2023-milestone__label t-uppercase green">Fund Research</div> </div> <h3 class="t-h5--semibold">Collaborative Computational Tools for a Human Cell Atlas</h3> <p>We make <a href="https://chanzuckerberg.com/human-cell-atlas-collab/" target="_blank" rel="noopener">investments to develop more interoperable data and advanced computational methods</a> necessary to integrate and build models. Bringing cutting-edge machine learning, AI, statistics and other modeling to single-cell data is critical to extracting insights from complex biological data, like single-cell datasets.</p> </div> </div> <div class="al-2023-milestone" data-milestone="cellxgene-annotate"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/cellxgene-annotate.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2017</div> <div class="al-2023-milestone__label t-uppercase turqiose">Build Tools</div> </div> <h3 class="t-h5--semibold">CELLxGENE Annotate</h3> <p>We build <a href="https://cellxgene.cziscience.com/docs/05__Annotate%20and%20Analyze%20Your%20Data/5_0__Get%20Started" target="_blank" rel="noopener">CELLxGENE Annotate</a>, an open source tool that allows scientists to collaborate to analyze and annotate large single-cell datasets.</p> </div> </div> <div class="al-2023-milestone" data-milestone="seed-networks-for-a-human-cell-atlas"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Seed-Networks-for-the-Human-Cell-Atlas.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2018</div> <div class="al-2023-milestone__label t-uppercase green">Fund Research</div> </div> <h3 class="t-h5--semibold">Seed Networks for the Human Cell Atlas</h3> <p>We launch the <a href="https://chanzuckerberg.com/science/programs-resources/single-cell-biology/seednetworks/" target="_blank" rel="noopener">Seed Networks for the Human Cell Atlas</a> grant to bring together experimental scientists, computational biologists, software engineers, and physicians to create a high volume of standardized datasets across different tissues and organs. This project funds 38 collaborative science teams — representing 20 countries and over 200 labs — and has supported the delivery of foundational data from more than 15 human organs.</p> </div> </div> <div class="al-2023-milestone" data-milestone="cellxgene-discover"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/cellxgene-discover-w.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2020</div> <div class="al-2023-milestone__label t-uppercase turqiose">Build Tools</div> </div> <h3 class="t-h5--semibold">CELLxGENE Discover</h3> <p>We roll out <a href="https://cellxgene.cziscience.com/" target="_blank" rel="noopener">CELLxGENE Discover</a>, a data platform that democratizes access and enables easy exploration of the growing amounts of single-cell data being generated by researchers worldwide, as well as data from the Human Cell Atlas. Many of the datasets from grants we've funded and the San Francisco Biohub — including Tabula Sapiens and the COVID-19 Tissue Atlas — are available in Discover.</p> </div> </div> <div class="al-2023-milestone" data-milestone="covid-19-tissue-atlas"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/COVID-19-Response.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2020</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">COVID-19 Response</h3> <p>We leverage our infectious disease expertise to focus on supporting efforts to curb the pandemic, from <a href="https://chanzuckerberg.com/blog/a-model-for-the-nation-building-a-covid-19-testing-lab-in-only-eight-days/" target="_blank" rel="noopener">standing up a testing facility in just eight days</a> to working with 22 California Departments of Public Health to <a href="https://chanzuckerberg.com/newsroom/chan-zuckerberg-initiative-chan-zuckerberg-biohub-the-state-of-california-partner-to-track-covid-19-spread-statewide/" target="_blank" rel="noopener">track the spread of COVID statewide</a> and building data around SARS-CoV-2 through the <a href="https://covid-tissue-atlas.ds.czbiohub.org/" target="_blank" rel="noopener">COVID-19 Tissue Atlas</a>. This dataset employs single-cell techniques to document the human body's response to SARS-CoV-2 infection in six different organs.</p> </div> </div> <div class="al-2023-milestone" data-milestone="single-cell-biology-data-insights"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/scb.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2021</div> <div class="al-2023-milestone__label t-uppercase green">Fund Research</div> </div> <h3 class="t-h5--semibold">Single-Cell Biology Data Insights</h3> <p>Our work to build and support single-cell tools continues with the launch of the first cycle of Data Insights grants, which support <a href="https://chanzuckerberg.com/science/programs-resources/single-cell-biology/data-insights/?cycle=1,2" target="_blank" rel="noopener">researchers and computational experts</a> who are advancing tools and resources to process large volumes of single-cell data using machine learning methods. These projects use large collections of data and employ advanced modeling to make sense of multiple datasets.</p> </div> </div> <div class="al-2023-milestone" data-milestone="pediatric-and-ancestry-networks-for-a-human-cell-atlas"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Pediatric-and-Ancestry-Networks.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2021</div> <div class="al-2023-milestone__label t-uppercase green">Fund Research</div> </div> <h3 class="t-h5--semibold">Pediatric and Ancestry Networks</h3> <p>Our <a href="https://chanzuckerberg.com/science/programs-resources/single-cell-biology/pediatric-networks/" target="_blank" rel="noopener">Pediatric Networks</a> and <a href="https://chanzuckerberg.com/science/programs-resources/single-cell-biology/ancestry-networks/" target="_blank" rel="noopener">Ancestry Networks</a> grants aim to make data for the Human Cell Atlas more representative of different ancestries and age groups — which addresses knowledge gaps and helps ensure the data being used to train large language models is more inclusive of the diversity of human biology.</p> </div> </div> <div class="al-2023-milestone" data-milestone="chan-zuckerberg-biohub-network"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Chan-Zuckerberg-Biohub-Network.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2021</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">Chan Zuckerberg Biohub Network</h3> <p>Building on the success of the San Francisco Biohub's unique collaborative model, we announce the creation of the <a href="https://www.czbiohub.org/" target="_blank" rel="noopener">Biohub Network</a> — a group of nonprofit research institutes bringing together scientists, engineers and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons.</p> </div> </div> <div class="al-2023-milestone" data-milestone="chan-zuckerberg-institute-for-advanced-biological-imaging"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/czi-cryoet-data-portal.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2022</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">Chan Zuckerberg Institute for Advanced Biomedical Imaging</h3> <p>We bring together a range of diverse disciplines at the <a href="https://www.czimaginginstitute.org/about/" target="_blank" rel="noopener">Imaging Institute</a> to develop revolutionary new imaging hardware and software tools that will help researchers see and understand cellular dynamics in living systems in a broader biological context.</p> </div> </div> <div class="al-2023-milestone" data-milestone="opencell"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Open-Cell.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2022</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">OpenCell</h3> <p>The San Francisco Biohub develops <a href="https://opencell.czbiohub.org/" target="_blank" rel="noopener">OpenCell</a>, which provides protein localization data for more than 1,300 functionally critical human proteins, along with a map of more than 30,000 interactions among proteins within cells.</p> </div> </div> <div class="al-2023-milestone" data-milestone="tabula-sapiens"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Tabula-Sapiens.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2022</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">Tabula Sapiens</h3> <p>Stemming from early collaboration with our Seed Networks research, scientists at the San Francisco Biohub generate data about the cells within our organs and tissues and publish <a href="https://www.science.org/doi/10.1126/science.abl4896" target="_blank" rel="noopener">The Tabula Sapiens</a>. The team uses unique methods to map human cell types by measuring gene expression in nearly 500,000 cells from 24 different tissues and organs, most obtained from the same donor.</p> </div> </div> <div class="al-2023-milestone" data-milestone="biohub-new-york-chicago"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/CZ-Biohub-Network-Expands.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2023</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">Biohub Network Expands</h3> <p>We welcome two new institutes to our Biohub Network: </p> <p><a href="https://www.czbiohub.org/chi/" target="_blank" rel="noopener">Chicago Biohub</a>, which is embarking on work to embed miniaturized sensors into tissues that will allow us to monitor molecular and cellular signals with the goal of understanding and treating the inflammatory states underlying many diseases.</p> <p><a href="https://www.czbiohub.org/ny/" target="_blank" rel="noopener">New York Biohub</a>, which focuses on bioengineering immune cells — the only cells in our bodies that come in contact with virtually all of our organs — so scientists can identify diseases early and potentially treat them. Initial disease targets include cancers such as ovarian and pancreatic cancer and neurodegenerative diseases like Parkinson's and Alzheimer's.</p> </div> </div> <div class="al-2023-milestone" data-milestone="cryoet-data-portal"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/czi-cryoet-data-portal.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2023</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">CryoET Data Portal</h3> <p>The <a href="https://www.czimaginginstitute.org/tools/" target="_blank" rel="noopener">Imaging Institute</a> uses cryo-electron tomography (cryoET) to generate 3D images of cell structures and biomolecules, like proteins, in cells. Along with researchers worldwide, they are compiling imaging datasets into the cryoET data portal — a cloud-based <a href="https://cryoetdataportal.czscience.com/" target="_blank" rel="noopener">community database</a> that aims to provide machine learning experts access to training data, helping researchers find insights faster. By creating an easy-to-use portal, more researchers will be able to deposit data, develop new, quicker processing methods, and interpret biological significance. </p> </div> </div> <div class="al-2023-milestone" data-milestone="zebrahub"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Zebrahub.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2023</div> <div class="al-2023-milestone__label t-uppercase navy">Do Science</div> </div> <h3 class="t-h5--semibold">Zebrahub</h3> <p>San Francisco Biohub publishes the <a href="https://zebrahub.ds.czbiohub.org/" target="_blank" rel="noopener">Zebrahub</a> project, a dynamic, open source atlas of zebrafish development integrating advanced microscopy and single-cell biology. Zebrahub provides scientists a detailed understanding of how tissues, organs and whole organisms develop from a single cell.</p> </div> </div> <div class="al-2023-milestone" data-milestone="human-breast-cell-atlas"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/Human-Breast-Cell-Atlas.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2023</div> <div class="al-2023-milestone__label t-uppercase green">Fund Research</div> </div> <h3 class="t-h5--semibold">Human Breast Cell Atlas</h3> <p>A team of researchers from The University of Texas MD Anderson Cancer Center; UC, Irvine; and Baylor College of Medicine publish the <a href="https://chanzuckerberg.com/blog/human-breast-cell-atlas-nicholas-navin/" target="_blank" rel="noopener">Human Breast Cell Atlas</a>. Through work we helped fund from the Seed Network grants, researchers now have a stronger understanding of immune involvement in breast biology, which will help inform how scientists approach the development of more targeted treatments. <a href="https://cellxgene.cziscience.com/collections/48259aa8-f168-4bf5-b797-af8e88da6637" target="_blank" rel="noopener">All the data from this research</a> and <a href="https://cellxgene.cziscience.com/collections" target="_blank" rel="noopener">several key atlas efforts</a> are available on CELLxGENE Discover, which other scientists can use to help accelerate their own research.</p> </div> </div> <div class="al-2023-milestone" data-milestone="svg-cellxgene-census"> <div class="al-2023-milestone__img"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/annual-letter/2023/milestones/CELLxGENE-Census.png" alt=""> </div> <div class="al-2023-milestone__copy"> <div class="al-2023-milestone__year"> <div class="t-body--small">2023</div> <div class="al-2023-milestone__label t-uppercase turqiose">Build Tools</div> </div> <h3 class="t-h5--semibold">CELLxGENE Census</h3> <p>We announce <a href="https://chanzuckerberg.github.io/cellxgene-census/" target="_blank" rel="noopener">Census</a>, which provides scalable access to the largest collection of single-cell data from more than 500 individual datasets and over 33 million unique cells, giving researchers easy access for their own analysis needs such as developing AI models. Census' scalable infrastructure is critical to accelerate the work of researchers in the modern era of big data. Today, nearly 1000 researchers access it weekly, including a lab that's developing large foundation models like scGPT.</p> </div> </div> </div> </div> </section> <section class="al-2023-letter bottom"> <div class="content-story__text "> <div class="content-block__body t-body--large"> <h2 class="t-h4--semibold text-center">The Path Forward With AI</h2> <p>Looking back, it's easy to see how each step in our journey was a building block that laid the groundwork for CZI to take advantage of recent AI advancements, so we can make progress faster. And these milestones are just a part of the work happening across our science teams that have led us to where we are today.</p> <p>Right now, <a href="https://chanzuckerberg.com/newsroom/czscience-builds-ai-gpu-cluster-predictive-cell-models/" target="_blank" rel="noopener">we are building an AI computing system</a> that will be used to train models that describe cell systems based on datasets CZI and the scientific community have been assembling since some of our earliest grants. Once it's up and running, it will be one of the world's largest AI clusters for nonprofit scientific research — and, eventually, it will power predictive virtual models of our cells. As we move deeper into understanding our cells and their interactions, the data will be increasingly complex. Combining these predictive virtual cells with the power and promise of large language models will enable our teams and collaborators to continue to work toward our north star of supporting the science to end disease. Scientists will be able to use these models to see how cells may respond to specific conditions — for example, how an immune cell responds to an infection, what happens at the cellular level when a child is born with a rare disease, or even how a patient's body will respond to a new medication. By showing us what happens to cells when a change is introduced, these virtual models of cells will allow researchers to quickly answer questions and choose the highest-yield research and clinical trials.</p> <h2 class="t-h4--semibold">Co-Building Tech Tools With Teachers</h2> <p>Beyond science, we've also focused on the CZI-shaped problems that we are uniquely positioned to take on in the education field to help unlock the potential of every child, no matter who they are or where they live. Our work is now at an important inflection point as we <a href="https://chanzuckerberg.com/education/impact" target="_blank" rel="noopener">reflect on the impact of eight years</a> of grantmaking and building technology to advance research on student learning and human development — and its translation into classroom practice.</p> <p>Despite important progress, many research-backed resources and tools still aren't reaching students and teachers. That's why we're exploring new ways to leverage our grantmaking and technology capabilities to co-build tools with teachers and students grounded in underutilized research and support whole child approaches to education.</p> <p>This work will expand on what we've learned from developing technology — such as <a href="https://chanzuckerberg.com/education/impact/along/" target="_blank" rel="noopener">Along</a> and <a href="https://chanzuckerberg.com/education/impact/summit-learning/" target="_blank" rel="noopener">Summit Learning</a> — so we can equip educators with <a href="https://chanzuckerberg.com/blog/future-education-work/" target="_blank" rel="noopener">tools that address key education challenges</a>. As we continue to build, we will thoughtfully consider opportunities to accelerate research-backed practices by using AI. As always, our approach will be informed by feedback from researchers, experts and educators.</p> <h2 class="t-h4--semibold">Our Collective Impact</h2> <p>When we started CZI, we couldn't have predicted exactly where we are now. But at every turn, our goal has been to leverage and advance technology to accelerate impact across science and education.</p> <p>So, thank you to our team and our family of partners. We are proud to have done <a href="https://chanzuckerberg.com/blog/2023-look-back/" target="_blank" rel="noopener">important work in 2023</a> — and we are ready for the opportunities 2024 has to offer.</p> <div class="signature signature--annual-letter"> <img class="signature__image" src="https://chanzuckerberg.com/wp-content/themes/czi/img/signature.svg" alt="Priscilla Chan & Mark Zuckerberg signature"> <div>Priscilla Chan & Mark Zuckerberg</div> <div>Co-Founders and Co-CEOs</div> </div> </div> </div> </section> </div> <footer class="footer"> <div class="footer__header"> <div class="footer__logo t-h6--semibold"> <img src="https://chanzuckerberg.com/wp-content/themes/czi/img/logo-minified.svg" alt="Chan Zuckerberg Initiative logo"> <span>Building A Better Future for Everyone</span> </div> <div class="footer__socials desktop-only"> <p class="t-nav">Follow Us</p> <div> <a href="https://www.facebook.com/chanzuckerberginitiative/" target="_blank" class="button-social button-social-- button-social--facebook" title="View our facebook page (Opens in new window)" aria-label="View our facebook page (Opens in new window)"></a> <a href="https://www.instagram.com/chanzuckerberginitiative/" target="_blank" class="button-social button-social-- button-social--instagram" title="View our instagram page (Opens in new window)" aria-label="View our instagram page (Opens in new window)"></a> <a href="https://www.threads.net/@chanzuckerberginitiative/" target="_blank" class="button-social button-social-- button-social--threads" title="View our threads page (Opens in new window)" aria-label="View our threads page (Opens in new window)"></a> <a href="https://www.linkedin.com/company/chan-zuckerberg-initiative/" target="_blank" class="button-social button-social-- button-social--linkedin" title="View our linkedin page (Opens in new window)" aria-label="View our linkedin page (Opens in new window)"></a> <a href="https://twitter.com/ChanZuckerberg" target="_blank" class="button-social button-social-- button-social--twitter" title="View our twitter page (Opens in new window)" aria-label="View our twitter page (Opens in new window)"></a> <a href="https://www.youtube.com/channel/UCZioJ6fb9SuRdLIO7DlE09w" target="_blank" class="button-social button-social-- button-social--youtube" title="View our youtube page (Opens in new window)" aria-label="View our youtube page (Opens in new window)"></a> </div> </div> </div> <div class="footer__body"> <nav class="footer__nav desktop-only"> <ul class="footer__nav-list"> <li class="footer__nav-list-item footer__nav-list-item--heading t-nav">About Us</li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/about/our-approach/">Our Approach</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/about/leaders/">Our Leadership</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/about/annual-letter/year-2023/">Annual Letter</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/about/investing-our-endowment/">Investing our Endowment</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/ethics-policies/">Ethics Policies and Guidelines</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/careers/">Careers</a></li> </ul> <ul class="footer__nav-list"> <li class="footer__nav-list-item footer__nav-list-item--heading t-nav">What We Do</li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/science/">Science</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/education/">Education</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/community/">Community</a></li> </ul> <ul class="footer__nav-list"> <li class="footer__nav-list-item footer__nav-list-item--heading t-nav">How We Work</li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://tech.chanzuckerberg.com/">Technology</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/grants-ventures/">Grants & Ventures</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/dei/">Diversity, Equity, Inclusion & Accessibility</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/movement-capacity-building/">Capabilities & Resources</a></li> </ul> <ul class="footer__nav-list"> <li class="footer__nav-list-item footer__nav-list-item--heading t-nav">News & Stories</li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/newsroom/">Newsroom</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/blog/">Stories</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/videos/">Videos</a></li> <li class="footer__nav-list-item t-h7--semibold"><a href="https://chanzuckerberg.com/newsroom/media-gallery/">Media Gallery</a></li> </ul> </nav> <div class="footer__socials mobile-only"> <p class="t-nav">Follow Us</p> <div> <a href="https://www.facebook.com/chanzuckerberginitiative/" target="_blank" class="button-social button-social-- button-social--facebook" title="View our facebook page (Opens in new window)" aria-label="View our facebook page (Opens in new window)"></a> <a href="https://www.instagram.com/chanzuckerberginitiative/" target="_blank" class="button-social button-social-- button-social--instagram" title="View our instagram page (Opens in new window)" aria-label="View our instagram page (Opens in new window)"></a> <a href="https://www.threads.net/@chanzuckerberginitiative/" target="_blank" class="button-social button-social-- button-social--threads" title="View our threads page (Opens in new window)" aria-label="View our threads page (Opens in new window)"></a> <a href="https://www.linkedin.com/company/chan-zuckerberg-initiative/" target="_blank" class="button-social button-social-- button-social--linkedin" title="View our linkedin page (Opens in new window)" aria-label="View our linkedin page (Opens in new window)"></a> <a href="https://twitter.com/ChanZuckerberg" target="_blank" class="button-social button-social-- button-social--twitter" title="View our twitter page (Opens in new window)" aria-label="View our twitter page (Opens in new window)"></a> <a href="https://www.youtube.com/channel/UCZioJ6fb9SuRdLIO7DlE09w" target="_blank" class="button-social button-social-- button-social--youtube" title="View our youtube page (Opens in new window)" aria-label="View our youtube page (Opens in new window)"></a> </div> </div> </div> <div class="footer__copyright t-body--medium"> © 2024 The Chan Zuckerberg Initiative | <a href="https://chanzuckerberg.com/privacy/"> Privacy </a> | <a class="optanon-show-settings">Do Not Sell or Share My Personal Information</a> | <a href="https://chanzuckerberg.com/sitemap/"> Sitemap </a> </div> </footer> <div class="cookie-banner" cookie-banner> <p>We use cookies to help us improve the site and to inform our marketing and digital content efforts. If you choose ‘Don’t Enable,’ sites you’re logged into – like Facebook and Twitter – may still be able to identify you as a visitor to this site. <a href="https://chanzuckerberg.com/cookies-and-other-information/">Learn more</a>. </p> <button class="cookie-banner-cta cookie-banner-cta__button cta-square" data-action="deny">Don't Enable</button> <button class="cookie-banner-cta cookie-banner-cta__button cta--red" data-action="accept">Accept</button> </div> </main> <div id="breakpoints"></div> </div> <script type="text/javascript" id="chan-zuckerberg-navigation-js-extra"> /* <![CDATA[ */ var tagEn = {"current":"production","ajaxurl":"https:\/\/chanzuckerberg.com\/wp-admin\/admin-ajax.php","nonce":"a61eb428f6"}; /* ]]> */ </script> <script type="text/javascript" src="https://chanzuckerberg.com/wp-content/themes/czi/js/app.js?m=1732665746g" ></script><script type="text/javascript" src="//fast.wistia.com/assets/external/E-v1.js?ver=1.0.0" id="chan-zuckerberg-wistia-js"></script> <script type="text/javascript" src="//cdn.split.io/sdk/split-10.25.2.min.js?ver=10.25.2" id="split-js-js"></script> <script type="text/javascript" src="https://chanzuckerberg.com/wp-includes/js/jquery/ui/core.min.js?m=1732206023g" ></script><script type="text/javascript" src="https://chanzuckerberg.com/wp-includes/js/jquery/ui/datepicker.min.js?ver=1.13.3" id="jquery-ui-datepicker-js"></script> <script type="text/javascript" id="jquery-ui-datepicker-js-after"> /* <![CDATA[ */ jQuery(function(jQuery){jQuery.datepicker.setDefaults({"closeText":"Close","currentText":"Today","monthNames":["January","February","March","April","May","June","July","August","September","October","November","December"],"monthNamesShort":["Jan","Feb","Mar","Apr","May","Jun","Jul","Aug","Sep","Oct","Nov","Dec"],"nextText":"Next","prevText":"Previous","dayNames":["Sunday","Monday","Tuesday","Wednesday","Thursday","Friday","Saturday"],"dayNamesShort":["Sun","Mon","Tue","Wed","Thu","Fri","Sat"],"dayNamesMin":["S","M","T","W","T","F","S"],"dateFormat":"M d, yy","firstDay":1,"isRTL":false});}); /* ]]> */ </script> <script type="text/javascript" id="wpsbc-script-js-extra"> /* <![CDATA[ */ var wpsbc = {"ajax_url":"https:\/\/chanzuckerberg.com\/wp-admin\/admin-ajax.php","search_form_nonce":"c6f2d5a278","search_date_format":"M d, yy","calendar_months_to_jump":""}; /* ]]> */ </script> <script type="text/javascript" src="https://chanzuckerberg.com/wp-content/plugins/wp-simple-booking-calendar-premium/assets/js/script-front-end.min.js?m=1693938840g" ></script><script type="text/javascript" src="https://stats.wp.com/e-202448.js" id="jetpack-stats-js" data-wp-strategy="defer"></script> <script type="text/javascript" id="jetpack-stats-js-after"> /* <![CDATA[ */ _stq = window._stq || []; _stq.push([ "view", JSON.parse("{\"v\":\"ext\",\"blog\":\"153223128\",\"post\":\"29947\",\"tz\":\"-8\",\"srv\":\"chanzuckerberg.com\",\"hp\":\"vip\",\"j\":\"1:14.0\"}") ]); _stq.push([ "clickTrackerInit", "153223128", "29947" ]); /* ]]> */ </script> </body> </html>